HOCCO.DOG

Ofertas sugeridas de otras empresas

• Tusclasesparticulares

  

  Teletrabajo - Profesor/a Particular - Sin Experiencia

  hace 5 meses

  Badalona

  No se requiere experiencia previa como profesor.

• Carrerasresearch

  

  VAC_55_2026 - POSTDOCTORAL RESEARCHER (Blood Stem Cell Identity group)

  hace 5 días

  Badalona

  ppWe are looking for a Junior Postdoctoral Researcher for the Blood Stem Cell Identity group, led by Dr. Vincenzo Calvanese. /p h3Research Description /h3 pHematopoietic stem cells (HSC) are a life‑saving therapy for leukemia and have expanded applications in gene and cell therapy against other cancers, genetic, autoimmune, and infectious diseases. Practical limitations such as donor‑matching or insufficient cell number render these therapies unfeasible or unsuccessful for many patients. This postdoctoral researcher will work on a project aimed at understanding the transcriptional and developmental mechanisms that govern the emergence, self‑renewal and maturation of human HSC, and their relevance for the establishment and maintenance of the leukemia stem cell population in the context of blood cancer. The research will combine directed differentiation of human pluripotent stem cells, in‑vitro and in‑vivo models of human normal and leukemic development, and state‑of‑the‑art epigenomic and transcriptomic profiling of cell lines and human primary tissues. /p h3Main Responsibilities /h3 ul liDesign and perform cell culture assays and directed differentiation assays of hematopoietic stem cell sources including primary HSC (cord blood / bone marrow) /li liDifferentiate human pluripotent stem cells toward hematopoietic and endothelial fates, organoid assays and generate iHSC or other hematopoietic lineages. /li liGenerate and characterize CRISPR‑Cas9 genome‑edited and fluorescent reporter pluripotent stem cell lines to track and interrogate developmental transitions. /li liPerform cell surface marker analysis, cell enrichment and isolation by flow cytometry, MACS and FACS, and confocal/immunofluorescence imaging of normal and leukemic hematopoietic cells and tissues. /li liPrepare samples and libraries for single‑cell RNA‑seq, spatial transcriptomics, and ATAC‑seq, and carry out downstream molecular biology (RNA/gDNA/cDNA, PCR, qPCR, Sanger sequencing). /li liPerform in‑vivo assays of hematopoietic potential, including transplantation and analysis of immunodeficient mouse models. /li liCoordinate with team members, bioinformaticians and collaborators to extract the maximum biological information from experiments and datasets, ensuring smooth communication and integration of expertise. /li liContribute to data interpretation and the preparation of clear, publication‑ready figures and presentation materials. /li liSupport and guide junior team members and students, fostering standardized and rigorous experimental approaches within the group. /li liMaintain well‑organized records of protocols, samples and data, ready for internal and external use. /li liPresent research data within the team, across the institute and in collaborative settings, and disseminate project findings through talks and posters at national and international meetings; lead and contribute to the preparation of manuscripts for peer‑reviewed publication. /li liPrepare and submit applications for competitive postdoctoral fellowships and complementary funding aligned with the scope of the project, in coordination with the group leader. /li /ul h3Qualifications /h3 ul liPhD in Cell Biology, Developmental Biology, Stem Cell Biology or a related discipline. /li liStrong hands‑on expertise in human hematopoietic and pluripotent stem cell culture and in‑vitro directed differentiation. /li liExperience in genetic engineering (CRISPR‑Cas9, reporter line generation and characterization). /li liExpertise in flow cytometry, FACS/MACS cell isolation, immunofluorescence and confocal imaging. /li liExperience with functional hematopoietic assays (e.g. EHT, CFU) is highly desirable. /li liExperience with sample and library preparation for single‑cell transcriptomics, spatial transcriptomics and/or ATAC‑seq. /li liSolid molecular biology skills (RNA/DNA work, PCR, qPCR, sequencing). /li liA background in hematopoiesis, stem cells, or tissue/cancer biology is highly desirable. /li liFamiliarity with basic bioinformatic analysis (e.g. R, Seurat for single‑cell RNA‑seq) is a plus, together with willingness to develop these skills further. /li liA proven track record of peer‑reviewed publications, conference presentations, and collaborations. /li liStrong motivation, excellent organizational skills, and the ability to work collaboratively and support team members. /li liExcellent spoken and written English. /li liIndependent thinking, enthusiasm, pro‑activity, impeccable work ethics and professionalism. Commitment to an equity, diversity, and inclusion‑based, international working environment. /li /ul h3Benefits and Contract /h3 ul liPostdoctoral contract linked to the project "Overcoming the Epigenetic Drift in Culture‑Expanded Blood Adult Stem Cells", ATR2023‑ , funded by MICIU/AEI. /li liFull‑time contract (39 hours/week). /li liHighly competitive salary. /li liJoin a dynamic, international, multidisciplinary and forward‑thinking lab, recently established with the support of the EU (ERC‑CoG), Wellcome, FJC, and Spanish government funding. /li liWork alongside a diverse and inclusive team of scientists at various training and experience levels, fostering mutual support, constructive feedback, and productive collaboration. /li liThe stimulating environment of the Barcelona metropolitan area. /li liContribute to pioneering research within the inspiring setting of the Josep Carreras Leukaemia Research Institute. /li /ul h3Deadline /h3 pApply by July . /p h3Equal Opportunity Statement /h3 pThe IJC is an equal‑opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, or other legally protected characteristics. /p /p #J-18808-Ljbffr

• IGTP Retreat

  

  Lab Manager — Neuroimmunology Research Team

  hace 2 días

  Badalona

  pIGTP invites applications for a Lab Manager to support the Neuroimmunology Team with organizational, technical, and administrative duties. The role focuses on day-to-day lab operations, safety and security, staff training, and cross-disciplinary collaboration. /ppIdeal candidates hold a Master in cellular, molecular biology or immunology, with proven project management experience, excellent planning skills, and fluent English. /p #J-18808-Ljbffr

• Euraxess

  

  Laboratory Technician — Stem Cell & Immunotherapy Research

  hace 4 días

  Badalona

  pJosep Carreras Leukaemia Research Institute (IJC) invites applications for a Laboratory Technician in the Stem cell biology, developmental leukemia and immunotherapy group led by Dr. Pablo Menéndez. /ppThe role focuses on supporting mouse colonies and in vivo experiments within a translational cancer research environment. The candidate should hold a biology-related degree, have experience with laboratory animals, and demonstrate teamwork, organization, and willingness to learn. /p #J-18808-Ljbffr

• Carrerasresearch

  

  VAC_57_2026 - RESEARCH ASSISTANT IN TRAINING

  hace 2 días

  Badalona

  ppThe Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive bcancer research center /b dedicated to research and innovation in leukaemia. /p pWe are looking for a bResearch Assistant in Training /b in the Nuclear architecture in leukemia group led by Dr. Gregoire Stik. /p h3RESEARCH DESCRIPTION /h3 pThe main goal of our lab is to uncover novel biomolecular mechanisms driving the development of B-cell acute lymphoblastic leukemia. We are focusing on understanding the role of oncogenic fusion proteins induced by chromosomal translocations on chromatin organization, gene expression and how they ultimately participate in disease progression. /p pThe project aims to unravel the molecular mechanisms that regulate the function of fusion oncoproteins by integrating multiple experimental and computational approaches, including genome editing, optogenetics, high-resolution microscopy, and chromatin conformation capture. /p pUnderstanding how translocations can affect biochemical properties of protein will offer potential new biomedical applications for the treatment of haematological malignancies. /p h3MAIN RESPONSIBILITIES /h3 ul liDesign and construct various mutant forms of a target oncogene using molecular cloning techniques. /li liConduct functional assays to evaluate the biological activity of oncogene mutants in appropriate cellular models. /li liMaintain accurate experimental records and analyze data to assess the impact of specific mutations. /li liCollaborate with other lab members to optimize experimental protocols and interpret results. /li /ul h3WHAT WE NEED /h3 ul liMaster’s degree in biomedical sciences or similar. /li liPrevious experience in a research laboratory. /li liAn excellent academic record. /li liHigh level of communication skills and teamwork abilities. /li liStrong background in cellular and molecular biology, with additional expertise in epigenetics considered an advantage. /li liProficiency in English (spoken and written). /li liOrganized, independent, proactive, self‑motivated, and enthusiastic. /li /ul h3WHAT WE OFFER /h3 ul liTemporary position: 1 year (Training contract) with possibility to continue as PhD candidate. /li liFull time contract of 39 hours per week. /li li“Este contrato está vinculado al proyecto PID OA-I00 financiado por MCIN/AEI/ / / FEDER, UE.” /li liMeasures to reconcile work and family life (flexible work schedule, working days of vacation and days for personal matters). /li liFlexible remuneration program (kindergarten and other measures). /li liAn exciting and innovative research project. /li liWorking in the mixed basic and clinical research environment of the Josep Carreras Leukaemia Research Institute. /li liIncorporation in a multinational and highly collaborative team. /li liThe stimulating environment of the Barcelona metropolitan area. /li /ul h3DEADLINE /h3 pPlease submit your application by July 30th, 2027. /p pThe IJC is an equal‑opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, or other legally protected characteristics. /p /p #J-18808-Ljbffr

• IGTP Retreat

  

  Cancer Immunology Research Technician

  hace 2 días

  Badalona

  pIGTP Retreat on the Can Ruti Campus near Barcelona seeks a motivated researcher for a temporary position in the Innate Immunity Unit. The project focuses on CD5L's role in modulating tumor-associated macrophage responses and immunotherapy opportunities. /ppThe role involves in vitro analyses of macrophages, biomarker studies, and data analysis with R, alongside manuscript preparation and participation in seminars and conferences. /p #J-18808-Ljbffr

• Carrerasresearch

  

  Predoctoral Researcher: Leukemia Transcriptional Dynamics

  hace 2 días

  Badalona

  pPredoctoral Researcher – Transcriptional Dynamics in Leukemia Group at Carrerasresearch in the Barcelona metropolitan area is seeking a motivated predoctoral researcher. You will apply genome‑wide sequencing, CRISPR editing, and molecular biology methods to study epigenetic modifiers and transcription factors in leukemia development. /ppYou will handle human samples, perform library preparation, ChIP, and RNA-seq analyses, and contribute to in vitro experiments with primary cells and established /p #J-18808-Ljbffr

• Euraxess

  

  VAC_55_2026 - POSTDOCTORAL RESEARCHER

  hace 4 días

  Badalona

  ppOrganisation/Company Josep Carreras Leukaemia Research Institute (IJC) Research Field Medical sciences » Cancer research Researcher Profile Recognised Researcher (R2) Positions PhD Positions Application Deadline 28 Jul 2026 - 00:59 (Europe/Madrid) Country Spain Type of Contract Temporary Job Status Full-time Hours Per Week 39 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No /p h3Offer Description /h3 pThe Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive bcancer research center /b dedicated to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases. It was created in 2010, and since then has experienced an exponential growth. /p pThe IJC is also part of the network of Excellence Research Centers of Catalonia b(CERCA) /b and was accredited as a bSevero Ochoa Center of Excellence /b by the Ministry of Science, Innovation, and Universities in 2024. Since 2018, the Institute has also been accredited by the Scientific Foundation of the Spanish Association Against Cancer b(FCAECC) /b Additionally, IJC is one of the centers integrated into the Institut de Recerca Germans Trias i Pujol (IGTP) accreditation as Accredited Health Research Institute (IIS) by the Carlos III Health Institute b(ISCIII) /b. /p pThe IJC's main headquarters is located within the Can Ruti Biomedical Campus, alongside other leading biomedical institutions, providing direct access to cutting‑edge scientific and technological facilities, as well as complementary community services. The IJC has bsix locations integrated into reference hospitals /b: Hospital Germans Trias i Pujol, Hospital Clínic, Hospital Sant Pau, Hospital Josep Trueta, Hospital del Mar and Hospital San Joan de Déu. This facilitates close collaboration between basic and clinical researchers, fostering translational research that integrates basic science with clinical practice in clinical settings. /p pWe are looking for a bJunior Postdoctoral Researcher /bfor the Blood Stem Cell Identity group, led by bDr. Vincenzo Calvanese. /b /p h3Research Description /h3 pHematopoietic stem cells (HSC) are a life‑saving therapy for leukemia, and have found broadened applications in gene and cell therapy against other cancers, genetic, autoimmune, and infectious diseases. Yet practical limitations, such as donor‑matching or insufficient cell number, render these therapies unfeasible or unsuccessful for many patients. Attempts to overcome these limitations have been unable to create a reliable source of HSC for patients: while we can generate human HSC from pluripotent stem cells, they resemble early developmental stages, lacking many of the functional maturation hallmarks. /p pThe Postdoctoral Researcher will join the team to work on a project aimed at understanding the transcriptional and developmental mechanisms that govern the emergence, self‑renewal and maturation of human HSC, and their relevance for the establishment and maintenance of the leukemia stem cell population in the context of blood cancer. To dissect the nature and function of these cells, we combine directed differentiation of human pluripotent stem cells, in vitro and in vivo models of human normal and leukemic development, and state‑of‑the‑art epigenomic and transcriptomic profiling of cell lines and human primary tissues. This work will provide important advances in our understanding of human blood stem cell biology in the context of normal and neoplastic hematopoiesis. /p h3Main Responsibilities /h3 ul liDesign and perform cell culture assays and directed differentiation assays of hematopoietic stem cell sources including primary HSC (cord blood / bone marrow) /li liDifferentiation and culture of human pluripotent stem cells toward hematopoietic and endothelial fates, organoid assays and generation of iHSC or other hematopoietic lineages. /li liGenerate and characterize CRISPR‑Cas9 genome‑edited and fluorescent reporter pluripotent stem cell lines to track and interrogate developmental transitions. /li liPerform cell surface marker analysis, cell enrichment and isolation by flow cytometry, MACS and FACS, and confocal/immunofluorescence imaging of normal and leukemic hematopoietic cells and tissues. /li liPrepare samples and libraries for single‑cell RNA‑seq, spatial transcriptomics, and ATAC‑seq, and carry out downstream molecular biology (RNA/gDNA/cDNA, PCR, qPCR, Sanger sequencing). /li liPerform in vivo assays of hematopoietic potential, including transplantation and analysis of immunodeficient mouse models. /li liCoordinate with team members, bioinformaticians and collaborators to extract the maximum biological information from experiments and datasets, ensuring smooth communication and integration of expertise. /li liContribute to data interpretation and the preparation of clear, publication‑ready figures and presentation materials. /li liSupport and guide junior team members and students, fostering standardized and rigorous experimental approaches within the group. /li liMaintain well‑organized records of protocols, samples and data, ready for internal and external use. /li liPresent research data within the team, across the institute and in collaborative settings, and disseminate project findings through talks and posters at national and international meetings; lead and contribute to the preparation of manuscripts for peer‑reviewed publication. /li liPrepare and submit applications for competitive postdoctoral fellowships and complementary funding aligned with the scope of the project, in coordination with the group leader. /li /ul h3Qualifications /h3 ul liPhD in Cell Biology, Developmental Biology, Stem Cell Biology or a related discipline. /li liStrong hands‑on expertise in human hematopoietic and pluripotent stem cell culture and in vitro directed differentiation. /li liExperience in genetic engineering (CRISPR‑Cas9, reporter line generation and characterization). /li liExpertise in flow cytometry, FACS/MACS cell isolation, immunofluorescence and confocal imaging. /li liExperience in functional hematopoietic assays (e.g. EHT, CFU) is highly desirable. /li liExperience with sample and library preparation for single‑cell transcriptomics, spatial transcriptomics and/or ATAC‑seq. /li liSolid molecular biology skills (RNA/DNA work, PCR, qPCR, sequencing). /li liA background in hematopoiesis, stem cells, or tissue/cancer biology is highly desirable. /li liFamiliarity with basic bioinformatic analysis (e.g. R, Seurat for single‑cell RNA‑seq) is a plus, together with willingness to develop these skills further. /li liA proven track record of peer‑reviewed publications, conference presentations, and collaborations. /li liStrong motivation, excellent organizational skills, and the ability to work collaboratively and support team members. /li liExcellent spoken and written English (please submit all documentation in English). /li liIndependent thinking, enthusiasm, pro‑activity, impeccable work ethics and professionalism. Commitment to an equity, diversity, and inclusion‑based, international working environment. /li /ul h3Benefits /h3 ul liPostdoctoral contract linked to the project "Overcoming the Epigenetic Drift in Culture‑Expanded Blood Adult Stem Cells", ATR , funded by MICIU/AEI / ). /li liHighly competitive salary. /li liJoin a dynamic, international, multidisciplinary and forward‑thinking lab, recently established with the support of the EU (ERC‑CoG), Wellcome, FJC, and Spanish government funding. /li liWork alongside a diverse and inclusive team of scientists at various training and experience levels, fostering mutual support, constructive feedback, and productive collaboration. /li liThe stimulating environment of the Barcelona metropolitan area. /li liContribute to pioneering research within the inspiring setting of the Josep Carreras Leukaemia Research Institute. /li /ul h3Selection Process /h3 pTo apply for this opportunity, please submit your application by July 28, 2026. /p /p #J-18808-Ljbffr