Synthetic Chemist – Peptide Synthesis Specialist
hace 7 días
Murcia
Role Overview: We are seeking a talented and detail-oriented Synthetic Chemist with demonstrated hands-on experience and expertise in peptide synthesis o support our expanding drug discovery programs. The successful candidate will contribute to the design, synthesis, purification, and characterization of peptides and peptidomimetics, working closely with multidisciplinary teams in a dynamic and collaborative environment. Key Responsibilities: • Design and execute solid-phase peptide synthesis (SPPS) using automated synthesizers and manual techniques., • Develop and optimize synthetic routes for linear and cyclic peptides, including complex modifications and conjugations., • Perform purification using preparative HPLC, SFC, MPLC chromatography, and other relevant techniques., • Characterize compounds using HRMS, NMR, and other analytical tools., • Collaborate with medicinal chemists and biologists to support SAR studies and lead optimization., • Document experimental procedures and results in electronic lab notebooks (ELNs) and contribute to internal reports and publications., • Ensure compliance with Eurofins’ quality standards and safety protocols. Qualifications: • Ph.D. or M.Sc. in Organic Chemistry, Medicinal Chemistry, or related discipline., • Minimum 2–5 years of hands-on experience in peptide synthesis, preferably in a CRO or pharmaceutical setting., • Proficiency with automated peptide synthesizers (e.g., Biotage, CEM Liberty Blue)., • Strong understanding of protecting group strategies, coupling reagents, and resin selection., • Experience with peptidomimetics, macrocyclization, or conjugation chemistry is highly desirable., • Experience in parallelization using automated platforms is also highly desirable, • Excellent problem-solving skills and attention to detail., • Strong communication skills and ability to work effectively in a team-oriented environment. Why Join Us: • Work in a cutting-edge research environment with access to state-of-the-art facilities., • Be part of a global scientific network with opportunities for growth and collaboration., • Contribute to impactful drug discovery projects that advance human health.
