Bioinformatics Developer Ensembl Compara
hace 16 horas
Manchester
We are seeking a highly motivated and experienced bioinformatics developer to help expand the Comparative Genomics resources in ___, a world-leading provider of genomics data, infrastructure, and tools. There are a growing number of global biodiversity initiatives, such as Darwin Tree of Life, the Vertebrate Genomes Project, the European Reference Genome Atlas and the Human pangenome reference graph consortium, providing high-quality reference genomes and pangenomes for eukaryotic species. Ensembl provides a platform for the annotation and comparison of these genomes, from the single-species pangenome level right up to annotating and modelling the evolutionary relationships across all eukaryotes. You will join the Ensembl Comparative Genomics team, whose work spans computational biology, software development, large-scale computing, big data, workflow management and automation. The Comparative Genomics team provides resources to help researchers understand the relationships between species. The team generates data on orthologues, gene trees, large scale syntenies, whole genome alignments and a variety of other analyses. A primary objective is to ensure these analyses remain scalable with the growing influx of high-quality genomes being added each year. As part of the Comparative Genomics team you will work with the Eukaryotic Annotation team and several other teams in the Ensembl project, as well as research consortia and communities from across the globe. On joining the team, you will play a key role in developing software and workflows to compare thousands of genomes, directly contributing to making Ensembl a world leading resource for the comparative analysis of genomic diversity. Ensembl Compara is part of the Genome Analysis Team, led by Emily Clark, and the team operates within the broader Ensembl infrastructure. You will report directly to Jitender Cheema, Comparative Genomics Project Lead. Your primary tasks will be to maintain, run and develop our Comparative Genomics pipelines. This will include working closely with collaborators and gaining in-depth knowledge of gene and species tree inference, multiple genome alignment, workflow managers and Python-based technologies. Your Key Responsibilities Will Include • Maintaining, running, and developing the Ensembl Comparative Genomics pipelines, databases and API., • Assisting the project leader in making technical decisions for the project., • Helping with the coordination of the Ensembl comparative genomics release process., • Supporting external users in their use of the comparative genomics pipelines., • Applying scientific expertise to advance resource development., • Participation in collaborations between Ensembl and other research groups and scientific consortia and representing the project and the institute at conferences. You have • Master/PhD in bioinformatics or molecular biology, bioinformatics, data sciences or a related field (or equivalent practical experience)., • Strong knowledge of comparative genomics, including whole-genome alignment, gene and species-tree reconstruction, sources of bias/error and associated software and tools., • Excellent understanding of algorithm development and performance optimisation for large scale data., • Experience in bioinformatics and the management of genomics data., • Proficiency in at least one programming language (e.g., Python), • Excellent proficiency working on a UNIX/Linux environment, using command-line tools and version control., • Proficiency with relational databases and SQL., • Hands-on experience with Workflow systems Nextflow/Snakemake, or similar., • Experience with Singularity/Docker to run containers on a shared compute environment and workflow optimisation., • Excellent organisational and communication skills. You may also have • Experience working on high-performance clusters and cloud computing or GPU-based acceleration., • Working within a release cycle for software or data., • Experience with MongoDB and building GraphQL APIs., • Experience in driving and leading software development projects., • Working knowledge of machine learning concepts., • Experience working on scientific projects in the field of comparative genome analysis. Other Helpful Information Contract length: 3 years (grant based) Salary: 5 or 6 depending on qualifications and experience, monthly salary at £3,303 or £3,695 after tax but excluding pension and insurance contributions. Plus generous benefits Why join us Do something meaningful At ___ you can apply your talent and passion to accelerate science and tackle some of humankind's greatest challenges. EMBL-EBI, part of the European Molecular Biology Laboratory, is a worldwide leader in the storage, analysis and dissemination of large biological datasets. We provide the global research community with access to publicly available databases and tools which are crucial for the advancement of healthcare, food security, and biodiversity. Join a culture of innovation We are located on the Wellcome Genome Campus, alongside other prominent research and biotech organisations, and surrounded by beautiful Cambridgeshire countryside. This is a highly collaborative and inclusive community where our employees enjoy a relaxed atmosphere. We are committed to ensuring our employees feel valued, supported and empowered to reach their professional potential. Watch this ___ to see how EMBL-EBI makes an impact. Enjoy Lots Of Benefits • Financial incentives: Monthly family, child and non-resident allowances, annual salary review, pension scheme, death benefit, long-term care, accident-at-work and unemployment insurances, • Flexible working arrangements - including hybrid working patterns, • Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover), • Generous time off: 30 days annual leave per year, in addition public holidays, • Relocation package including installation grant (if required), • Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely), • Family benefits: On-site nursery, 10 days of child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances, • Benefits for non-UK residents: Visa exemption, education grant for private schooling, financial support to travel back to your home country every second year and a monthly non-resident allowance. For detailed information please visit our employee benefits page ___. What else you need to know • International applicants: We recruit internationally and successful candidates are offered visa exemptions. Please take a look at our ___ page for further information., • EMBL is a signatory of DORA. Find out how we apply DORA principles to our recruitment and performance assessment processes ___., • Diversity and inclusion: At EMBL, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ+ & individuals from all nationalities., • How to apply: To apply please submit a cover letter and a CV through our online system. Applications will close at 23:59 CET on the date shown below. We aim to provide a response within two weeks after the closing date. Closing Date 12/01/2026