Trabajos protocol en BusheyCrear alertas

About Us: Endpoint is an interactive response technology (IRT®) systems and solutions provider that supports the life sciences industry. Since 2009, we have been working with a single vision in mind, to help sponsors and pharmaceutical companies achieve clinical trial success. Our solutions, realized through the proprietary PULSE® platform, have proven to maximize the supply chain, minimize operational costs, and ensure timely and accurate patient dosing. Endpoint is headquartered in Raleigh-Durham, North Carolina with offices across the United States, Europe, and Asia. Position Overview: The Project Manager is the primary client interface for client implementations, from initial engagement to study closedown. Project Managers are responsible for managing projects through the software development lifecycle and through study maintenance while working collaboratively with teammates and maintaining exceptional client satisfaction. This position can be based remotely within UK • Independently lead projects of moderate to high complexity., • Act as primary point of contact for clients, keeping them apprised of all project developments while maintaining stellar client satisfaction., • Build effective partnerships with other internal teams to move project through all phases of the development process., • Develop and maintain project schedule, identify, and track milestones and identify and manage cross-functional dependencies and risks., • Act as subject matter expert on client clinical study protocol., • Manage ongoing reporting of project health and profitability to internal and external stakeholders., • Conduct end-user training., • Manage issue resolution for studies in maintenance, including troubleshooting and root cause analysis, where necessary., • Bachelor's degree or equivalent preferred, or appropriate work experience., • 2-4 years’ experience in a software Project Management role, with a proven ability to understand technical concepts and learn very quickly., • 2-4 years’ experience in the life science industry, • Previous experience working in a fast-paced, entrepreneurial environment preferred., • Prior experience delivering voice (IVR) web (IWR) and mobile (IMR) platforms a big plus., • Familiarity using SQL a plus, • Strong attention to detail and quality-focus, • Strong customer service orientation, • Excellent organizational and time management skills, • Good communication skills, • Excellent organizational skills, • Strong interpersonal skills with the ability to work effectively with a wide variety of professionals, • Able to work on multiple assignments with moderate supervision £45,000 - £50,000 a year Benefits: All job offers will be based on a candidate’s location, skills and prior relevant experience, applicable degrees/certifications, as well as internal equity and market data. Regular, full-time or part-time employees working 30 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(K), Paid time off (PTO) or Flexible time off (FTO), and Company bonus where applicable. Endpoint Clinical does not accept unsolicited resumes from search firms or any other third parties. Any unsolicited resume sent to Endpoint Clinical will be considered Endpoint Clinical property, and Endpoint Clinical will not pay a fee should it hire the subject of any unsolicited resume. #LI-MT #LI-RemoteWe may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

We are seeking a skilled Python Developer with experience in the trading domain and FIX protocol to join our dynamic team. Python Developer in the trading domain. Develop, maintain, and enhance trading applications using Python.

Remote (UK-based) | Full-Time Reactive Markets is the 2026 OTC Trading Platform of the Year (_). Our network handles over $50 billion in daily trading volumes across FX, Equities, and Cryptocurrency, connecting 40+ of the world's leading liquidity providers. We build trading systems that operate at the edge of what's technically possible — where nanoseconds matter and a dropped message costs real money. Our engineering team is small, senior, and deeply invested in the craft of building cutting edge, reliable, high-performance systems. We're looking for a C++ Software Engineer who wants to build low-latency trading infrastructure on Linux. You'll work on the core components of our Switchboard trading platform — pricing engines, connectivity gateways, market-data systems, and the messaging layer that ties them together. This is not a role where you write code and throw it over a wall. You build it, you test it, you deploy it, you support it in production, and you improve it. Our engineers own the full lifecycle — from design through to operational excellence. When something breaks at 4pm on a Friday, you're part of the team that investigates and fixes it. Occasional hours outside the normal working day are required for production releases, scheduled maintenance windows, and Level 3 support during critical incidents. We keep this to a minimum and recognise the commitment — but owning a production trading platform means being there when it matters. Modern C++20 and Go on Linux — a modern software stack based on open source Cloud-native infrastructure on AWS with colocation in key data centres Microsecond-level latency optimisation and high-throughput messaging Market-data and reference-data pipelines across multiple asset classes FIX protocol integrations with global banks and liquidity providers Observability and monitoring — dashboards, alerting, and metrics that make system behaviour visible Production systems that handle real money — reliability is not optional Technical: Strong C++ with Linux systems programming (3+ years) Comfortable working close to the metal — you understand what's underneath your code Experience with performance-sensitive systems (profiling, optimisation, deterministic behaviour) Familiarity with networking fundamentals (TCP/UDP, socket programming) Go experience is a strong bonus — we use Go extensively for microservices and command-line tooling, and you'll be expected to work with it internally. If you don't know it yet, strong C++ engineers pick it up quickly Python for scripting, automation, testing, and data analysis — used across the platform for tooling and operational workflows Git and shell scripting Experience in financial services or trading technology is a plus but not essential How you work: You ship. You're delivery-focused — you iterate, you improve, you get things into production You own it. When you build something, you take responsibility for its behaviour in production. You respond to incidents (15-minute acknowledgement SLA during working hours), investigate issues, and close the loop You write things down. Documentation is not an afterthought — it's how we scale knowledge across a distributed team. If it's not written down, it doesn't exist You communicate. We're a distributed team across multiple time zones. Clear, proactive communication — especially when things go wrong — is essential You care about quality. You write clean, testable code. You review your peers' work thoughtfully. You push for continuous improvement without gold-plating You embrace AI tooling. We use AI tools (Claude, Gemini) to amplify our engineering capability — from code review and debugging to incident investigation and documentation. You don't need to be an expert, but you should be curious and willing to learn Real problems — trading systems where performance is measured in microseconds, not user clicks An excellent team — senior engineers who care about craft, collaborate openly, and hold each other to high standards Ownership — small teams, clear accountability, direct impact on the platform and our clients Competitive package — up to 30 days leave + bank holidays, private health insurance, pension, life insurance, dental/optical cashback, cycle to work, socials and offsites Remote-friendly — work from home with flexibility. We trust our people to deliver Sustainable pace — we work hard, but we don't burn people out. Balance is how we stay sharp Growth — career progression to senior roles, performance specialisation, or technical leadership. We invest in people who invest in us We believe in transparency, honest feedback, and writing things down. We celebrate delivery, not activity. We frame AI as empowering people — removing toil, amplifying capability, enabling higher-value work. We aim to build systems that don't depend on the heroics of individuals to maintain and support — systems and processes that are resilient, documented, and sustainable. We keep our process focused and respectful of your time. Our process follows three stages. Stage 1: Initial Conversation with Talent Acquisition Format: Video call, ~30-45 minutes Stage 2: Hiring Manager Conversation with the relevant team lead or hiring manager Format: Video call, ~60 minutes Stage 3: Technical Interview with two members of the relevant engineering team Format: Video call, interactive session, ~60 minutes What to expect in each stage will be explained by Talent Acquisition if you're invited to interview. Throughout the process, we aim to keep momentum with no unnecessary delays between stages, and feedback typically comes within a few business days. *Please note that depending on availability, Stage 2 and 3 may swap around. Please apply directly via this job posting — all applications, including those submitted via LinkedIn, are managed through our applicant tracking system, so you'll always land in the same place regardless of where you found this role. Right to Work: Candidates must have the existing right to work in the UK. We are not currently able to offer visa sponsorship for this role. Equal Opportunities: Reactive Markets is an equal opportunities employer. We welcome applications from all qualified candidates regardless of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. Reasonable Adjustments: If you need any adjustments or support during the application or interview process, please let us know — we're happy to accommodate. Data Protection: By applying, you consent to Reactive Markets processing your personal data for recruitment purposes, in line with our . #Hiring #SoftwareEngineering #CPlusPlus #FinTech #TradingTechnology #RemoteWork #LowLatency

Description This role will be mainly remote but require flexibility to travel to client sites, and our offices based in London, Sheffield, and Bristol. About the role As a Senior Microsoft Power Platform and AI Developer, you will work with users, product teams, engineers, architects, security and operational colleagues to turn complex needs into reliable services. You will take technical ownership of significant components and end-to-end solutions and guide decisions across low-code, pro-code, integration and AI patterns. A major part of the role is engineering AI agents and agentic workflows. You will design how agents use trusted knowledge, approved tools, Model Context Protocol (MCP) services, approvals, human hand-offs and safe failure paths. You will ensure that evaluation, observability, identity, permissions and data boundaries are built into delivery rather than added later. You will review code and designs, mentor developers, improve engineering practices and support live services. You should be able to challenge inappropriate use of low-code or AI and select a simpler or more supportable approach where evidence supports it. Key responsibilities • Lead the design, build, test, deployment and support of solutions using Power Apps, Power Automate, Dataverse, Copilot Studio and appropriate pro-code extensions., • Engineer AI agents and agentic workflows using trusted knowledge, tools, actions, approvals, human hand-offs, evaluation and safe failure paths., • Design and implement integrations with approved MCP servers and lead development of MCP tools or services using secure, reusable patterns., • Integrate Power Platform and AI solutions with Microsoft 365, SharePoint, Microsoft Graph, Azure services and enterprise systems using connectors, APIs and event-based patterns., • Apply grounding, retrieval-augmented generation, structured outputs, tool calling and model-selection patterns with appropriate evaluation and operational controls., • Create custom connectors, plug-ins and Azure-hosted components where low-code capability is insufficient, choosing technologies based on need, risk and supportability., • Set and apply engineering standards for source control, solution packaging, environment strategy, automated testing, CI/CD, monitoring and release management., • Lead technical investigation of complex live-service faults and improve resilience, performance, accessibility, security and observability., • Review designs and code, mentor developers and contribute reusable components, patterns and learning to the wider engineering community. Requirements • Substantial hands-on experience designing, building and releasing production solutions with Power Apps, Power Automate, Dataverse and Copilot Studio., • Experience leading development of AI agents or agentic workflows that use knowledge, tools and actions to complete meaningful tasks safely., • Experience integrating or developing MCP servers and tools, or equivalent tool-based agent integration patterns, including troubleshooting identity, permissions and data flow., • Strong API and integration skills, including REST/JSON, custom connectors, OAuth 2.0, Microsoft Entra ID and secure secrets management., • Pro-code engineering capability in one or more languages such as TypeScript/JavaScript, C# or Python, with experience extending low-code services appropriately., • Strong software engineering practice, including testing, version control, code review, documentation, CI/CD, observability and supporting live services., • Ability to lead technical decisions for medium-to-high complexity work, communicate trade-offs and escalate architecture or security risks appropriately., • Practical understanding of security, data protection, accessibility and responsible AI controls for enterprise applications and agents. Desirable criteria • Experience with Azure Functions, Logic Apps, API Management, Key Vault, Application Insights, Azure AI services or comparable cloud components., • Experience with retrieval-augmented generation, vector search, embeddings, enterprise search and evaluation of grounded responses., • Experience with agent observability, tracing, prompt and version management, red teaming or automated quality and safety testing., • Experience integrating Microsoft Graph, SharePoint, Power BI, Fabric or other Microsoft enterprise services., • Experience defining Power Platform environment, solution, data-loss-prevention and application lifecycle management patterns., • Relevant Microsoft certifications, or experience delivering technology in government, justice, regulated or security-conscious environments. This role will require you to have or be willing to go through Security Clearance. As part of the onboarding process candidates will be asked to complete a Baseline Personnel Security Standard; details of the evidence required to apply may be found on the government website Gov.UK. If you are unable to meet this and any associated criteria, then your employment may be delayed, or rejected. Details of this will be discussed with you at interview. Benefits By joining us you can expect • Autonomy to develop and grow your skills and experience, • Be part of exciting project work that is making a difference in society, • Strong, inspiring and thought-provoking leadership, • A supportive and collaborative environment As well as this, we offer: • Development access to LinkedIn Learning, a management development programme and training, • Wellness 24/7 Confidential employee assistance programme, • Social - Breakfast Tuesdays, Thirsty Thursdays and Pizza on the last Thursday of each month as well as commitment to charitable causes, • Time off 25 days a year, • Pension Salary Exchange Scheme with 4% employer contribution and 5% employee contribution, • Life Assurance of 4 times base salary, • Private Medical Insurance which is non-contributory (spouse and dependants included), • Worldwide Travel Insurance which is non-contributory (spouse and dependants included)

Qumulo's cloud data platform manages exabytes of the world's most demanding data, unifying files, objects, and every workload across edge, core, and cloud. Customers are the lifeblood of our company and Qumulo is looking for strategic, customer-focused, and results-driven Customer Success Engineers (CSEs) with a strong background in cloud technologies. CSEs will engage and work with our customers to answer technical questions or resolve complex issues primarily focusing on cloud environments such as AWS and Azure. The CSE is ultimately responsible for the complete life cycle of a customer issue and ensuring proper communication and resolution. Troubleshoot issues on the Qumulo product in both On-Premises or Cloud file systems, including cloud infrastructure issues, permissions problems, performance issues, and general file system issues Prioritize and drive resolution for escalated customer issues in both cloud and on-premises environments Work cross-functionally with our sales, product, and engineering teams to ensure customer issues are quickly resolved Provide feedback to engineering and product teams on product gaps and areas of improvement, particularly related to cloud offerings Collaborate with peers and mentors on complex issues Consistently grow knowledge and expand skill sets in cloud technologies Multi-lingual with English as primary customer support delivery language Excellent written and verbal communication skills Strong problem-solving skills with a can-do attitude in a fast paced environment Demonstrated working knowledge of major cloud platforms, including compute, storage, networking, and identity management services Basic network troubleshooting skills and understanding of general network technologies Familiarity with Linux & Windows operating systems Familiarity with Windows Active Directory or LDAP Understanding of file permissions and access control in cloud environments 5 - 7 years experience in a customer-facing role, including 1-3 years of troubleshooting cloud environments Python Programming skills are a plus Relevant cloud certifications (e.g., AWS Certified SysOps Administrator, Microsoft Certified: Azure Administrator Associate) are a plus, but not required Must have the right to work in the UK without visa sponsorship. About Qumulo: Built for the most demanding enterprise workloads, from AI and HPC simulations to Splunk Observability, genomics and PACS medical imaging, geospatial datasets, media editing and rendering, and video surveillance, Qumulo unlocks the full power of an organization’s information. Our platform unifies file and object storage across data centers, edge, and public clouds, enabling efficient, accelerated computing and extending the reach of data unbound by protocol or transport limitations. With more than 1,100 customers and exabytes of data under management, Qumulo powers mission-critical workloads anywhere real-time access to massive file datasets is non-negotiable. Qumulo delivers radical simplicity, hardware freedom, exceptional customer support, and a true hybrid-cloud architecture. Our Values: At Qumulo, we are building an open and collaborative culture where people can do their best work with customers as our magnetic field. We act as owners, we share by default, we are data driven and experimental and as an inclusive workplace, we encourage and celebrate multiple points of view. As part of our culture we believe diversity drives innovation. Equal Opportunity Employer: Qumulo is an Equal Opportunity Employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, disability, military status, national origin, or any other characteristic protected under federal, state, or applicable local law. For more information on Qumulo's Applicant Privacy Policy, please visit: _

Are you interested in working directly for a single sponsor while having the security and additional career opportunities that working for a global CRO can bring? Our team says it’s the best of both worlds…. ClinChoice is searching for a Senior Statistical Programmer Consultant to join one of our clients. ClinChoice is a global full-service CRO with a strong focus on quality, professional development, and supportive culture. As a client-facing role, we are looking for confident candidates with the ability to work independently whilst establishing a high-trust environment with the client’s counterparts. Main Job Tasks and Responsibilities: The Senior Statistical Programmer Consultant is a delivery-focused role who works under the leadership, oversight, and direction of a Programming team leader to lead and/or support aspects of the programming effort to deliver technical programming and information components of a project. This position requires high technical skills and thorough industry knowledge to independently perform the Programming tasks Key Responsibilities: • Responsible for supporting the Programming deliveries of a clinical study or project., • Implements statistical programming aspects of the protocol and the clinical development program., • Ensures high quality is built into own deliverables and the quality delivered by other programmers., • Programs independently with high efficiency and quality., • Writes and/or implements specifications and oversees completeness of relevant documentation., • Contribute to the development of best practices to improve quality, efficiency, and effectiveness within the function., • Ensures compliance with standards and automation usage., • Plans and support team activities and tasks., • Communicates and escalates risks within the assigned studies and/or projects., • Works proactively with study team members including but not limited to the Statistician, Lead Programmer, Data Manager and Study Leader. Education and Experience: • Bachelor’s degree in computer science (CS), statistics, or related scientific disciplines with 5 yrs. of clinical programming (CDISC) experience; Master’s degree in CS, statistics or related disciplines with 6 yrs. of clinical programming (CDISC) experience., • Need to have Oncology TA experience., • Working knowledge of ICH and Good Clinical Practices, Clinical research, Clinical trial process, and related regulatory requirements and terminology., • Good understanding of the clinical drug development process., • Strong communication skills and coordination skills., • Current knowledge of technical and regulatory requirements relevant for the role, • Ability to proactively manage concurrent activities within a project, • Proficient ability to influence relevant stakeholders on programming-related items The Application Process Once you have submitted your CV, you will receive an acknowledgement that we received it. If you have the requirements we need, you will be invited for phone interview as the first step. Unfortunately, due to the number of applications we receive, we cannot reply to everyone individually if you are not successful. Who will you be working for? About ClinChoice ClinChoice is a global full-service CRO specializing in clinical development and functional solutions for pharmaceutical, biotechnology, medical device, and consumer health companies. We have over 28 years of proven high-quality delivery and results across all our services, with over 4,000 professionals in more than 20 countries across the Americas, Europe, and Asia-Pacific. Our Company Ethos Our mission drives our culture: to contribute to a healthier and safer world by accelerating the development and commercialization of innovative drugs and devices. Our employees are the most valuable company asset and they are the fulcrum around which all ClinChoice activities are built and close management and training is the core instrument to develop and maintain highly-qualified personnel. The continuous training keeps the resources qualified in terms of competence and expertise and gives all personnel the clear tools needed to manage both internal and client processes with the same methodology. The success of these core values is evidenced by our below industry average turnover rates. ClinChoice is an equal opportunity employer. We have based our success on attracting, developing, and promoting talent guided by diversity and inclusivity. Our employees come from very diverse backgrounds: gender, race, beliefs, and ethnicities. We recognize this is our strength and celebrate it. #LI-DNP

Please see the FAQs on the Protocol Education website for further details. Protocol Education is committed to safeguarding and promoting the welfare of children. For details of our privacy policy, please see visit the Protocol Education website.

I’m currently supporting a CRO looking to bring an experienced Freelance CRA onto a part-time, sponsor-dedicated project. The CRA will be based in the UK and work closely with both the CRO and sponsor teams, supporting sites as part of a global clinical trial. We’re particularly interested in CRAs who have experience working across international studies and ideally have previously supported sites in France. • Managing monitoring activities across assigned clinical trial sites, • Conducting site initiation, routine monitoring and close-out visits, • Managing site relationships and acting as a key point of contact for investigators and site teams, • Monitoring recruitment, data quality, site performance and key study metrics, • Identifying and escalating site-level risks and supporting resolution of study issues, • Ensuring compliance with the protocol, ICH-GCP and applicable local regulations, • Reviewing source documentation, study documentation and site files, • Supporting study start-up and site activation activities where required, • Completing monitoring reports and study documentation within agreed timelines, • Strong independent CRA and site monitoring experience, • Fluent in French and English, • UK based with the ability to travel for site visits when required, • Experience working on global/multinational clinical trials, • Previous experience monitoring or supporting clinical trial sites in France would be ideal, • Comfortable working across international and cross-functional study teams, • Strong knowledge of ICH-GCP and clinical trial regulations, • Oncology, Rare Disease and/or Neurology experience preferred, • Freelance / contract, • Part-time, • UK based, • Global clinical trial, • Site travel required #J-18808-Ljbffr

Protocol Education Ltd is looking for a Level 3 Nursery Practitioner to join their nursery team in Watford.

Everest Clinical Research (“Everest”) is a full-service contract research organization (CRO) providing a broad range of expertise-based clinical research services to worldwide pharmaceutical, biotechnology, and medical device industries. We serve some of the best-known companies and work with many of the most advanced drugs, biologics, and medical devices in development today. Everest has been an independent CRO since 2004 with a strong foundation as a statistical and data management center of excellence. Building on this foundation, Everest has successfully developed and established itself as a full-service CRO. Everest’s Corporate headquarters are located in Ontario Canada and US headquarters in New Jersey USA, with additional physical offices in Asia and Europe. Everest is known in the industry for its high-quality deliverables, superior customer service, and flexibility in meeting clients’ needs. A dynamic organization with an entrepreneurial origin, Everest continues to experience exceptional growth and great success. Quality is our backbone, customer-focus is our tradition, flexibility is our strength…that’s us…that’s Everest. To drive continued success in this exciting clinical research field, we are seeking committed, skilled, and customer-focused individuals to join our winning team as Senior Biostatistician, working remotely in the United Kingdom. • Lead efforts in resolving day to day work related issues and problems, securing quality, improving efficiency and productivity of statistical and programming operations., • Lead assigned projects by applying project management skills, statistical and programming techniques; achieve quality and on time delivery of deliverables, earn client’s trust and repeat business., • Provide statistical expertise for design, analysis and reporting of clinical trials and research projects., • Contribute to the writing of statistical sections of study protocols, perform sample size calculation, develop randomization specifications, and generate randomization codes., • Write Statistical Analysis Plans (SAPs) and properly address Peer Statistician review comments., • Create and maintain Statistical and Programming Quality Control (QC) and QA Plans for assigned projects., • Provide input to unblinded data management plan when required., • Assist in research and development of statistical methodologies and processes., • Develop and/or review ADaM dataset specifications. Review and provide input to SDTM dataset specifications when required., • Perform QC validation of analysis datasets and TLGs., • Perform third level review of dry runs and final run., • Lead statistical dry runs and final run by actively participating or contributing to project and resources management, addressing statistical and programming questions and interacting with data management to follow up and resolve data issues., • Review and provide input to the Analysis Data Reviewer’s Guide, discuss and incorporate Data Standards Reviewer’s review comments to ensure quality of the document., • Perform statistical analysis as per SAP, and address peer/QC review comments and findings., • Perform statistical validation of core results, address additional QC validation comments and findings on the core results., • Plan and conduct or contribute to the trial results reporting/dissemination meetings., • Under supervision contribute to the contents describing any deviation from the planned analysis and deviation from study conduct for the Clinical Study Report (CSR). Review CSR to ensure accuracy, completeness and appropriateness of the interpretation of the statistical results., • Write statistical report or statistical sections of the CSR., • Perform statistical analyses for publications, including but not limited to abstracts, manuscripts, presentations and posters., • Provide statistical input to Case Report Forms (CRF) design and database/variable structure., • Provide statistical input to non-CRF data collection and acquisition methods and approaches., • Review Data Management Plan sections relating to critical data collection and cleaning. Provide statistical input to Data Validation Specification., • Specify and/or program database quality acceptance checks, assess and report data quality issues, and follow through until resolution., • Perform ongoing assessment and communication of data quality issues, including protocol deviations., • Assist data management and trial management team in preparing for database lock. A Ph.D. degree in statistical science, mathematical analysis or related fields plus 2 years highly relevant experience or a Master’s degree plus 4 years highly relevant experience, with demonstrated ability and sustained performance. Everest is committed to upholding the principles of dignity, independence, integration, and equal opportunity. We welcome and encourage applications from people with disabilities, and upon request we will provide accommodations for candidates participating in any part of our recruitment and selection process. #J-18808-Ljbffr