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If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit ___ for more information. Brief Description: This role is responsible for providing strategic and operational leadership for global PV and REMS to execute the quality framework of controls and oversight necessary to achieve compliance, inspection readiness, and continuous improvement. Essential Functions/Responsibilities • Provide overall GRADS Compliance support in line with the execution of PV and REMS processes and compliance requirements, while ensuring data and scientific integrity practices are followed and consistent with global policies and procedures., • Work collaboratively with GRADS Compliance Operations to support the build and optimization of the GRADS Compliance organization. Activities include providing management analysis and advice on situations (existing or future state) for PV and REMS organizations. Offer recommendations on quality reports, performance metrics, and act as a key advisor on methodologies and tools used to achieve continuous improvement., • Sit on the extended leadership team of organizations supported to identify and mitigate risks, provide oversight to maintain a compliant state, monitor and influence key contributing metrics. Assist to improve and simplify processes (via BPO network) and introduce best practices for quality and compliance and identifies process gaps and facilitates resolutions congruent with industry best practices., • Participate in GRADS Compliance Council and support business to report on KPIs and escalated topics, • Stay current with health authority actions and emerging regulations in global PV and REMS and share insights and advice with functional area leadership team and review impacts on compliance., • Conduct after action reviews jointly with GRADS Compliance Operations with PV and REMS functional areas to learn and improve after any compliance incident., • Collaborate with GRADS Compliance Process and Training to design a strategy to pre-empt compliance issues., • Partner with GRADS Compliance Operations and GRADS Alliance Management to review metrics of vendors for compliance concerns and opportunities., • Participate along with GRADS Compliance Operations in Vendor Governance meetings led by GRADS Alliance Management and provide the functional area compliance lens in assessing data presented., • Participate in GRADS Alliance Management due diligence teams GRADS-wide Compliance as requested., • Partner with key stakeholders to resolve any global compliance or quality issues resulting from executed partnerships., • Partner with GRADS Compliance Operations to participate in the compliance analysis in complex situations and provides recommendations to management and senior leaders in support of CAPAs, commitments, and inspections., • Partner with PV and REMS to assist in the development of those area’s business continuity plans and provide guidance and leadership with future testing and execution of BCP as needed., • As a member of the GRADS Compliance Leadership team, responsible and accountable to make the quality and compliance of PV and REMS services such that these processes become enablers to the business and become a partner of choice., • Apply business and management expertise to drive operational performance across the organization., • Present complex processes, anticipate potential objections, and persuade others to adopt a different point of view if appropriate., • Act as an anchor to the commitment to data and scientific integrity, the efficient and effective use of systems, and driving quality & compliance proactively., • In conjunction with global PV and REMS Leaders, foster compliance leadership across procedures and processes, employing compliance oversight with reference to regulations as required., • Effectively engage Quality teams and support GRADS Compliance partner-aligned risk management strategies, plans, and processes., • Support Compliance Operations in inspection efforts and developing responses to regulator questions as required., • Responsible for PV and REMS knowledge transfer to GRADS Compliance and maintaining a current knowledge of industry compliance and quality trends., • 8 years R&D quality or compliance experience or relevant experience in global PV or REMS, • 5 + years’ experience in working with and directly communicating with senior leaders with proven accountability, and demonstrated excellent interpersonal, communication, negotiation, influencing, and problem-solving capabilities., • Proven ability to function autonomously at a senior level in a matrix model and in a team environment., • Travel Required: up to 30%, • Goes beyond the obvious and seeks novel approaches to complex issues., • Able to communicate complex information and analyses to a variety of scientific and non- scientific audiences in both verbal and written formats., • Works seamlessly with all levels of personnel and other R&D departments as well as quality, commercial, and manufacturing organizations., • Driver of innovative and creative solutions for achieving GRADS goals and objectives in a high quality and cost-effective manner., • Must be able to support highly complex multiple activities simultaneously., • Must have proven track record to be able to think critically, strategically, independently and problem solve., • Must have high level of motivation, drive, and demonstration of Jazz leadership values., • Top notch interpersonal skills in difficult situations, • Demonstrated sensitivity and knowledge of cultural differences with experience in multi-country, multi-cultural environments and demonstrated success with cross-geographically based cultural collaborations. FOR US BASED CANDIDATES ONLY Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $151,200.00 - $226,800.00 Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis. At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: ___.

Primary Graduate Teaching Assistant - Permanent Role - Brent Location: Brent, North London Start Date: September 2025 Contract: Permanent, Full-Time Salary: £25,000 - £27,000 (DOE) Are you a graduate with a passion for supporting children's learning and development? A thriving primary school in Brent is looking for a motivated Graduate Teaching Assistant to join their team from September 2025. This is a fantastic opportunity for graduates considering a future in teaching to gain paid, practical classroom experience in a supportive environment. The Role • Support pupils across EYFS, Key Stage 1 and/or Key Stage 2, • Deliver small group and 1:1 intervention's to boost progress in core subjects, • Provide classroom support, helping to create an engaging and inclusive learning environment, • Assist teachers with planning, preparation, and classroom management, • Support pupils with additional needs (including SEN and EAL), • Contribute to wider school life, including clubs, enrichment, and events What We're Looking For • A 2:1 or above degree (education, English, maths, science or related fields preferred), • Strong interest in primary teaching and child development, • Excellent communication and organisational skills, • A proactive, flexible and positive approach, • Previous experience working with children (school, tutoring, volunteering, mentoring) is desirable What the School Offers • A welcoming and inclusive primary school community, • Ongoing training and professional development (CPD), • Mentoring from experienced teachers and senior leaders, • Clear career progression into teacher training routes, • Excellent transport links across Brent This is a brilliant opportunity to gain invaluable experience as a Primary Graduate Teaching Assistant while making a real difference in pupils' learning and wellbeing. #aspirepeoplelondon Aspire People Limited provides services as an Education Agency and an Education Employment Business. Aspire People is committed to safeguarding and promoting the welfare of pupils and expects every candidate to share this commitment. Placements are subject, to appropriate Child Protection screening, including checks with former employers and the Disclosure and Barring Checks.

Secondary Science Graduate Teaching Assistant - Permanent Positions - Barnet Are you a recent Science graduate with a passion for inspiring young minds? Do you want to take your first steps towards a rewarding career in education? Aspire People are looking for enthusiastic Science Graduates to join our team and work within secondary schools across Barnet. One of our partner schools is a vibrant, diverse secondary school with a strong commitment to raising achievement in Science. You'll be joining a supportive team of staff who value creativity, innovation, and professional development. What We Offer: • Permanent positions available within Barnet secondary schools, • Paid opportunities to work as a Science Graduate Teaching Assistant or begin your journey towards teacher training, • Hands-on classroom experience supporting pupils aged 11-16, • Flexible options also available - daily supply and long-term placements, • Ongoing support from Aspire People's experienced education consultants What We're Looking For: • A recent Science graduate (Biology, Chemistry, Physics or related discipline), • A genuine passion for education and inspiring young people, • Strong communication and interpersonal skills, • A proactive, enthusiastic attitude towards learning and development The Role: • Supporting students in Science lessons to raise attainment and enthusiasm for the subject, • Working 1:1 or with small groups to boost confidence and understanding, • Assisting teachers in planning, preparation, and classroom management, • Taking on a long-term, permanent role within a dynamic Barnet secondary school, • Contributing to a positive, inclusive, and aspirational learning culture Whether you're considering a career in teaching or simply want to put your scientific expertise to good use, Aspire People can help you kickstart your journey. Apply today and start your journey as a Secondary Science Graduate Teaching Assistant in Barnet! #aspirepeoplelondon Aspire People Limited provides services as an Education Agency and an Education Employment Business. Aspire People is committed to safeguarding and promoting the welfare of pupils and expects every candidate to share this commitment. Placements are subject, to appropriate Child Protection screening, including checks with former employers and the Disclosure and Barring Checks.

If you are a current Jazz employee please apply via the Internal Career site. \n Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to \ntransform the lives of patients and their families. We are dedicated to developing \nlife-changing medicines for people with serious diseases — often with limited or no \ntherapeutic options. We have a diverse portfolio of marketed medicines, including leading \ntherapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. \nOur patient-focused and science-driven approach powers pioneering research and development \nadvancements across our robust pipeline of innovative therapeutics in oncology and \nneuroscience. Jazz is headquartered in Dublin, Ireland with research and development \nlaboratories, manufacturing facilities and employees in multiple countries committed to \nserving patients worldwide. Please visit\n more information. \n Brief Description: The Senior Analyst of Medical Affairs (Medical Education Grants) will be an integral member of the Medical Affairs, Medical Education Grant team. This role is essential for enhancing efficiency and effectiveness of the department’s operational and management of Independent Medical Education grant requests from external organizations. Essential Functions • Monitor the Educational Grant Management System and perform initial review of grant requests for completeness and alignment to industry and company guidelines, • Partner with Grants Manager to track routed requests against the budget to ensure approvals do not exceed the target forecast, • Process grant requests, to include communication of grant decisions to internal and external parties and issuing of payment to requestors, • Maintain a schedule of supported educational events across all Neuroscience molecules, • Track outcomes from supported programs, • Gather and assist analyze performance metrics under Grant Managers’ oversight and communicate the results to stakeholders within the organization as needed., • Prepare presentations for use by Grants Manager and other internal departments as needed, • Respond to reported problems and work with a diverse team of internal and external stakeholders to identify resolutions, • Schedule monthly EGRC meetings, distribute review materials to the team prior to the meeting, and prepare presentation materials, • Identify potential process improvements related to the grant workflow, • Update documentation related to IME grant processes and workflow diagrams to ensure business continuity and aid in continuous improvement efforts, • Communicate regularly with grant requestors regarding status, payment, program materials and outcomes of supported activities, • Analyze operational processes and systems and establish best practices, • Participate in professional meetings to evaluate the impact that regulatory and policy decisions have on IME grants, • Pharmaceutical industry and/or agency/medical education company experience is required, • Experience working with Microsoft Office, including Excel, PowerPoint, Outlook and Word is required, • Experience working with Pivot Tables, Macros and/or Visual Basic for Applications is preferred, • Experience working with publication software (e.g., Microsoft Publisher, Adobe InDesign) is desired, • Knowledge/understanding of FDA and regulatory guidelines for industry support of medical education events (e.g., PhRMA guidelines, OIG, AMA, ACCME, Sunshine Act) is desired, • Knowledge of CME/CE outcomes assessments (e.g., MOOREs, TELMs) is desired, • Experience working with reporting solutions (e.g., Izenda, SmartSheets) is desired FOR US BASED CANDIDATES ONLY Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $102,400.00 - $153,600.00 Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis. At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .

If you are a current Jazz employee please apply via the Internal Career site. \n Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to \ntransform the lives of patients and their families. We are dedicated to developing \nlife-changing medicines for people with serious diseases — often with limited or no \ntherapeutic options. We have a diverse portfolio of marketed medicines, including leading \ntherapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. \nOur patient-focused and science-driven approach powers pioneering research and development \nadvancements across our robust pipeline of innovative therapeutics in oncology and \nneuroscience. Jazz is headquartered in Dublin, Ireland with research and development \nlaboratories, manufacturing facilities and employees in multiple countries committed to \nserving patients worldwide. Please visit\n more information. \n The Principal will be responsible for supporting complex or leading singular projects related to data engineering requirements and initiatives across Jazz Research and Development. The Principal will support data projects from across the business including Clinical, Pre-Clinical, Non-Clinical, Chemistry, RWD and Omics. Essential Functions • Support the design, development and maintenance of data pipelines for processing Research and Development data from diverse sources (Clinical Trials, Medical Devices, Pre-Clinical, Omics, Real World Data) utilizing the AWS technology platform., • Create and optimize ETL/ELT processes for structured and unstructured data using Python, R, SQL, AWS services and other tools., • Build and maintain data repositories using AWS S3 and FSx technologies. Establish data warehousing solutions using Amazon Redshift., • Build and maintain standard data models., • Develop data quality frameworks, validation processes and KPIs to ensure accuracy and consistency of data pipelines., • Implement data versioning and lineage tracking to support data traceability, regulatory compliance and audit requirements., • Create and maintain documentation for data processes, architectures, and workflows., • Implement modern software development best practices (e.g. Code Versioning, DevOps, CD/CI)., • Support collaboration with RnD Researchers, Data scientists and Stakeholders to understand data requirements and deliver appropriate solutions in a global working model., • Maintain compliance with data privacy regulations such as HIPAA, GDPR, • Strong knowledge of data engineering tools such as Python, R and SQL for data processing., • Strong proficiency with AWS services particularly S3, Redshift, FSx, Glue, Lambda., • Strong proficiency with relational databases., • Strong background in data modeling and database design., • Familiarity with unstructured database technologies (e.g. NoSQL) and other database types (e.g. Graph)., • Familiarity with Containerization such as Docker and EKS/Kubernetes., • Familiarity with one or more RnD research process and associated regulatory requirements., • Exposure to healthcare data standards (CDISC, HL7, FHIR, SNOMED CT, OMOP, DICOM)., • Exposure to big data technologies and handling., • Knowledge of machine learning operations (MLOps) and model deployment., • Strong problem-solving and analytical abilities., • Excellent communication skills for collaborating with stakeholders., • Bachelor’s Degree in Computer Science, Statistics, Mathematics, Life Sciences, or other relevant scientific fields; Master’s Degree preferred, • Occasional mobility within office environment, • Routinely sitting for extended periods of time

If you are a current Jazz employee please apply via the Internal Career site. \n Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to \ntransform the lives of patients and their families. We are dedicated to developing \nlife-changing medicines for people with serious diseases — often with limited or no \ntherapeutic options. We have a diverse portfolio of marketed medicines, including leading \ntherapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. \nOur patient-focused and science-driven approach powers pioneering research and development \nadvancements across our robust pipeline of innovative therapeutics in oncology and \nneuroscience. Jazz is headquartered in Dublin, Ireland with research and development \nlaboratories, manufacturing facilities and employees in multiple countries committed to \nserving patients worldwide. Please visit\n more information. \n Brief Description: This position is responsible for leading efficient, innovative, clinical pharmacology and/or PK/PD studies from phase 1 to phase 4 through working with cross-functional team members. Essential Job Functions: Job Responsibilities • Development of the clinical pharmacology strategy of multiple programs spanning from candidate nomination for GLP toxicity studies through phase 4, • Support clinical study protocol (phase 1-4) development, PKPD data analysis/interpretation, and study report, • Serve as the clinical pharmacology Lead at cross function teams, and responsible for the dose selection and rationale in phase 1 studies and contribute to dose selections in clinical studies beyond phase 1, • Work with the pharmacometrics lead and relevant cross-function teams to plan and support PKPD modeling for internal or regulatory decision makings, • Contribute to the preparation of relevant sections of regulatory submissions including IND, and NDA/BLA documents, • Address queries from regulatory agencies during reviews and inspections, • Identify and manage consultants and vendors supporting clinical pharmacology studies, • PhD or MD with significant years of experience in clinical pharmacokinetic and pharmacokinetic-pharmacodynamic studies and data analysis/interpretations, • Strong understanding of clinical pharmacology and pharmacometrics principles and the drug development process, • Good working knowledge of software for PK/PD analysis (e.g. Phoenix WinNonlin, R, ADAPT and NONMEM), • Ability to work both independently and on strong cross functional teams, • Experience in regulatory submissions and agency interactions related to INDs, CTDs, NDAs or BLAs, • Excellent written and oral communication skills including good presentation skills Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .

Primary Graduate Teaching Assistant - Permanent Role Location: Barnet, North London Start Date: September 2025 Contract: Permanent, Full-Time Salary: £25,000 - £27,000 (dependent on experience) Are you a Russell Group graduate with a 2:1 or above in a core subject and a passion for education? A forward-thinking primary school in Barnet is offering a permanent opportunity for an ambitious graduate to join their team as a Graduate Teaching Assistant from September 2025. This is an ideal role for anyone considering a future in teaching or education. The Role: • Support learning across Key Stage 1 and/or 2, • Deliver targeted one-to-one and small group interventions, • Assist in planning and delivering engaging lessons, • Support pupils with diverse learning needs, including SEN, • Contribute to wider school life, including clubs and events What We're Looking For: • A 2:1 or higher degree from a Russell Group university (education, English, maths, science or related fields preferred), • A strong interest in teaching and child development, • Excellent communication, organisation, and teamwork skills, • A proactive, professional, and flexible attitude, • Experience with children (e.g. tutoring, mentoring, volunteering) is a plus What the School Offers: • A supportive, inclusive learning environment, • Mentoring from experienced educators, • Clear progression into teaching or educational careers, • Excellent CPD and training opportunities, • Strong transport links in Barnet This is a fantastic chance to gain paid, practical classroom experience while making a real impact. Apply now to take the first step in your teaching career #aspirepeoplelondon Aspire People Limited provides services as an Education Agency and an Education Employment Business. Aspire People is committed to safeguarding and promoting the welfare of pupils and expects every candidate to share this commitment. Placements are subject, to appropriate Child Protection screening, including checks with former employers and the Disclosure and Barring Checks.

🍩 Product Developer 📍 Watford & London (Hybrid – 3 days office / 2 days home) 🕒 Full-time | Permanent Got a taste for innovation? You could be the creative mind behind our next iconic doughnut. We’re looking for a curious, imaginative and hands-on Product Developer to join our team at Krispy Kreme UK. Based out of our Watford Factory (2 days) & London Office (1 day), you’ll help bring new flavours, formats, and ideas to life, working just one floor above where the magic happens. What you’ll be doing: • Develop mouth watering new doughnuts and baked treats, from everyday favourites to show stopping seasonal creations., • Own the journey from idea to launch: concepts, kitchen testing, specs, artwork, allergens. You name it., • Spot trends and turn them into tasty opportunities., • Collaborate closely with Marketing, Operations, and Supply Chain to roll out products successfully. What we’re looking for: • 3 years’ + experience in food product development. Especially in bakery or sweet treats? Even better., • A degree in Food Science, Culinary Arts or similar (or equivalent practical experience)., • Creative flair, commercial thinking, and a deep love of food., • Solid technical knowledge of ingredients and baking processes., • A collaborative mindset and great communication skills. Why Krispy Kreme? We’re a joyful brand with a purpose, to make people smile. At our Watford Innovation Kitchen, creativity meets craftsmanship, and you’ll be surrounded by a team that loves what they do (plus, the doughnut smell’s not bad either). Perks include: • 25 days’ holiday + bank hols (with the option to buy 5 more), • Hybrid working (3 office / 2 home), • Bupa private healthcare & wellbeing support, • 5% pension contribution (with 3% employer match), • 50% off doughnuts + 30% off drinks in-store, • Free Doughnut & Hot Drinks when you’re in the office!, • Treatbox Reward discounts & free parking 📣 Sound like your kind of role? Apply now and help shape the future of sweet innovation at Krispy Kreme UK. Let’s make the next big flavour together.