Stage manager jobs in Market HarboroughCreate job alerts

Scientist - Infectious Diseases - Oxford Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industrys most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.The primary purpose of this role is to contribute to cross functional efforts focused on applying the ImmTAX® platform or other modalities to the development of novel treatments for chronic infections, including HIV and HBV and EBV-associated diseases. The team is involved in multiple stages of the drug discovery and development process, from target discovery all the way to clinical trials. Examples of key preclinical research are published in Yang H et al., Mol Ther. 2016; 24,11; Fergusson J et al., Hepatology 2020; 72,5; Wallace Z et al., Mol Ther 2024; 32, 678.The postholder will plan, design and execute experimental investigations to support the advancement of the Company pipeline, processes and technology capabilities, with guidance from their manager, ensuring that project goals are met within time and budget constraints. They will be expected to demonstrate technical proficiency, rigour in assessing their own data and that of others, scientific creativity and independent thought. This position requires participation and presentation of results at internal meetings, sharing information learned at external scientific meetings and establishing productive relationships with colleagues across Research and other departments.Key Responsibilities: * With instruction and guidance from manager - plan, design, and execute assignments to meet project goals within defined timeframes* Execute experiments to address key scientific questions and enable project progression, utilizing range of molecular and cellular techniques including some of the following: NextGen sequencing, DD-PCR, qPCR, cell culture, flow cytometry, ELISpots, ELISAs,* Some work will be conducted in a containment level 3 (CL3 facility) and will require handling of human viruses* Analyse data, interpret results, and make recommendations* Proactively expand scientific/technical knowledge in relevant fields including HIV/HBV/EBV related disease biology and drug development through review of scientific literature/ conference updates, peer to peer mentoring, and attendance at seminars/conferences in line with company strategy* Work effectively in a matrixed team structure and as part of cross functional teams * Participate and present results at internal meetings* Establish relationships and possible collaborations within and outside of the companyEducation, Experience and Knowledge: Essential Qualifications: * PhD in molecular biology, cell biology, genomics, virology, immunology, or related discipline and 0-2 years related experience* Alternatively, a BSc or MSc with significant work experience in relevant scientific areas * Worked in a bench-based laboratory environment and proficient inthe following key techniques:o molecular techniques including some of the following: Droplet Digital PCR, NextGen sequencing, Genomics/Transcriptomics, PCR, Mutagenesis, qPCRo Culturing primary cells and/or cell linesPreferred Qualifications: * Knowledge/expertise of Immunology/HIV/HBV/EBV* Flow cytometry, ELISAs, ELISpots * Viral integration site analysis

Manager, External Financial Reporting - Oxford Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industrys most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.MAIN PURPOSE OF JOBTo work with the finance/accounting team on key specialised Group activities focusing on external reporting, technical accounting and SOX internal controls. A key position within the Finance organisation ensuring external deliverables are met for SEC reporting and UK Statutory accounting compliance, within a rapidly expanding and evolving business for a US-listed organisation. KEY RESPONSIBILITIES* External Reporting o Accountable for working with the Director, External Reporting for the Groups quarterly and annual financial reporting to the SEC, ensuring they are filed on a timely basis by co-ordinating across the various teams both within Finance and across the business to achieve this. o Responsibility for the consolidated plc accounts filed at Companies House and the subsidiary external financial reporting under IFRS.o Accountable for working with Director, External Reporting and the Business to understand the impact of new external financial reporting requirements that may arise as the Group expands its operations, using external support as required. o Accountable for forming the disclosures within all external financial reports ensuring the Groups activities are correctly and accurately presented in accordance with accounting standards and other appropriate regulations, in keeping with the Immunocore style.* Technical accountingo Responsibility for assessing and coordinating adoption of US GAAP and IFRS accounting updates and new accounting standards that may impact the Group, and ensuring all external financial reports are technically correct.o Accountable for working with process owners across Finance to review and understand how technical accounting matters (such as new transactions) will impact current processes and work with the wider Finance Team and business to ensure any accounting changes are successfully implemented.o Supporting the Senior Manager, External Reporting with finance review and data processing for share-based payment expenses, which are managed within an equity administration tool.* Sarbanes Oxleyo Support the External Reporting team and the third-party SOX internal control partner, as well as Finance, HR, IT and Legal, to ensure testing is completed and any observations or deficiencies are assessed for severity and identify any changes required in internal controls to ensure we maintain the level required for auditor certification, including a high level of understanding of the processes involved and identifying risks that require mitigating controls.o Working with the wider Finance Team and business, ensure all identified changes in processes or controls are implemented.o Support the External Reporting team with reviewing the overall internal control framework and identifying risk and control gaps or opportunities where we can simplify.Experience & KnowledgeEssential* Strong technical accounting experience in both IFRS and US GAAP * Experience of undertaking reporting to the SEC, including writing SEC-compliant disclosures * Experience of working in or closely with international companies, ideally with a US presence* Proven ability to drive change in a fast-moving environment * Evidence of credibility with management and external stakeholders* Experience of performing or testing internal controls in a SOX environment* ACA/ACCA/CIMA/CPA accounting qualification essential Desirable * Experience with Pharma/Biotech * Experience of UK statutory filings * Experience in public accountingKEY BEHAVIOURAL ATTRIBUTES* Openness and honestyReadily offering information pertaining to work in hand whether positive or negative. * Taking responsibilityBeing prepared to accept full responsibility for tasks entrusted to them; seeing tasks through to completion and dealing with the consequences of failure or success.* FlexibilityBeing flexible to new ideas and approaches; changes of plans, objectives and/or priorities. Handling disjointed tasks effectively. * Team spiritBeing able to work productively with others to achieve tasks. Showing consideration for the needs and feelings of others.Education & qualificationsProfessional accounting qualification