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The Staff Scientist will prepare grant applications and other scientific communication materials on a wide range of genomic research topics. This role is deeply immersed in the science of NYGC and supports our research team in building and expanding a successful, independently-funded research base. They collaborate with diverse teams of students, postdoctoral fellows, and principal investigators, and relates scientific and strategic goals to individual grant opportunities and other research communications vehicles. Typical grants include individual investigator, multi-PI and research center grants. Key Responsibilities • Takes a lead role in preparation and project management of individual and multi-investigator proposals;, • Provides advice on grantsmanship, editorial support and standardized language for administrative sections;, • Identifies opportunities for funding, • Manages the scientific writing process, including proposal management, team-building and coordination; establishing timelines and deliverables;, • Provides draft preparation, review and revision of grants and scientific writing., • Coordinates with and supports Sponsored Research staff to ensure timely, accurate application submission., • Edits manuscripts, fellowship applications, research progress reports, clinical research protocols and other research communications materials., • Interacts with lab members to independently develop new grant proposals., • Organizes small group meetings with lab members to review project progress, plan experiments, and integrate team data., • Assists in the design and planning of functional genomics and genetic perturbation experiments; and,, • Assists in analysis and figure preparation of diverse types of data, including high-throughput sequencing, microscopy images, gel images, and schematic diagrams. Key Responsibilities include (but are not limited to): • PhD in genetics, genomics, cancer biology, neuroscience or related discipline required;, • 5+ years research experience, including contributing to grant writing, required. NIH experience strongly desirable;, • Exceptional written communication skills required to prepare and edit competitive grant applications, publications, administrative materials, and other research communications;, • Ability to grasp complicated technical subjects, synthesize diverse lines of evidence and apply these abilities to technical writing required;, • Experience handling the scientific writing and project management process for multi-investigator and institutional grant applications strongly preferred;, • Experience with standard grant development concepts, practices, and procedures in a research environment preferred;, • Applied statistics background required, to perform power calculations and develop quantitative metrics for genomic assays;, • Ability to collaborate with diverse teams of investigators and administrative personnel required; and,, • Strong project management skills and experience required. Competencies • Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations, and delivers on commitments., • Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so., • Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity. Salary The salary range for this position is $62,000-78,000 per year. Base pay offered may vary depending on job-related knowledge, skills, and experience. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. About the New York Genome Center The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Equal Opportunity We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive. We believe that bringing together individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery. Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success. We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are protected veterans and individuals with disabilities. FLSA Status – Exempt This position is eligible for visa sponsorship and relocation assistance.

The Sanjana Lab at the New York Genome Center (NYGC) and New York University (NYU) is looking for a motivated individual to work as a Postdoctoral Research Associate within a highly creative and dynamic research team of scientists, bioengineers, human geneticists and computational biologists. The successful candidate will be mentored by Dr. Neville Sanjana on a project related to functional genomics and gene editing. Potential projects include Cas13-based profiling of noncoding RNAs in human neurons, in vivo CRISPR screens for immune and cancer phenotypes, protein design of new gene editors and cell therapies, and massively-parallel perturbations of enhancers and other functional noncoding genome elements. About the lab The Sanjana lab works at the intersection of genomics, synthetic biology and bioengineering. We are curious about many things and are passionate about what we do. We primarily develop new technologies for hacking and understanding biological systems. We try to learn from nature and to re-purpose what we learn to gain deeper insights into how genomes and neural systems function. In the lab, we modify genomes, perform high-throughput screens, differentiate human neurons from stem cells, find vulnerabilities in cancer cells using patient-derived organoids and have a lot of fun in the process. We aim to have a tangible impact on improving human health by creating new biological tools and fundamental biological discovery. About the position We are looking for a postdoctoral scientist eager to understand the impact of human genetic variation on gene expression and phenotypes at the cellular, tissue and physiological levels. Potential projects will combine cutting-edge human genetics and genome technology development. In addition, we envision that the postdoctoral scientist will play a major role in developing new projects in a supportive team science environment. To be considered for this role, please provide: 1) CV with a list of publications; 2) a short summary of your present and future research interests; 3) a list of three references and their contact information with your application. Required Skills The ideal candidate will hold a PhD or MD-PhD, have prior research experience in any of the following: molecular biology, biochemistry, computational biology and/or functional genomics and will have first-author publications. The candidate will be expected to plan and carry out research tasks independently and write-up/present findings on a regular basis. This position can be tailored to a candidate with strong molecular biology skills who are looking to improve their computational skills, or to a candidate with a stronger background in computational genetics or genomics looking to develop expertise in cutting-edge experimental methods. About NYGC: A cutting-edge environment for genomics NYGC is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer's, Parkinson's, Huntington's), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Salary The pay for this position is $88,000; this includes $70,000 base pay and an $18,000 per year taxable housing allowance. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. This includes Medical/Dental/Vision for employees & dependent(s); Vacation, Holidays, Sick, and Other Leave, including a paid winter break; a 401(k) match; Life Insurance; Flexible Spending Accounts; employee Tuition Reimbursement; flexible schedules and telework options for some positions; an Employee Assistance Program; and much more. Equal Opportunity We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive. We believe that bringing together individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery. Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success. We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are, protected veterans, and individuals with disabilities. FLSA Status - Exempt This position is eligible for visa sponsorship and relocation assistance.

The Lappalainen & Sanjana Labs at the New York Genome Center (NYGC) are looking for a motivated individual to work as a Postdoctoral Research Associate within a highly creative and dynamic research team of scientists, computational biologists, bioengineers, and human geneticists. The successful candidate will be jointly mentored by Drs. Tuuli Lappalainen and Neville Sanjana at the intersection of statistical genetics and functional genomics analyses and tech development and have the opportunity to also be affiliated with New York University. About the labs The Sanjana lab works at the intersection of genomics and bioengineering. We are curious about many things and are passionate about what we do. We primarily develop new technologies for hacking and understanding biological systems. We try to learn from nature and to re-purpose what we learn to gain deeper insights into how genomes and neural systems function. In the lab, we modify genomes, perform high-throughput screens, differentiate human neurons from stem cells, watch synapses rewire, find vulnerabilities in cancer cells and have a lot of fun in the process. We aim to have a tangible impact on improving human health by creating new biological tools and fundamental biological discovery. The Lappalainen lab studies functional genetic variation in the human populations by analyzing how genetic variants affect molecular and cellular traits, and how these cellular changes contribute to genetic risk for both common and rare diseases and traits. We analyze these questions both by computational analysis of large genomic, transcriptomic and multi-omic data sets, and by experimental approaches. Our lab includes experts across the field of systems genetics, from statistical genetics and genomics to molecular genomics. About the position We are looking for a postdoctoral scientist eager to understand the impact of human genetic variation on gene expression and phenotypes at the cellular, tissue and physiological levels. This position will be at the intersection of computational and wet-lab work, with co-mentorship by both PIs and membership in both labs. The projects for the postdoctoral scientist combines cutting-edge human genetics and genome technology development, with possible projects in CRISPR and single-cell multi-omics, and its integration with GWAS and eQTL data, including novel data from projects such as Developmental GTEx. Recently, the Sanjana and Lappalainen labs developed STING-seq (Systematic Targeted Inhibition of Noncoding GWAS loci with sequencing): ___. We seek to extend STING-seq to new cell types (including primary cells) and develop next-generation genome editing approaches to answer fundamental questions in human genetics, GWAS and disease biology. In addition, we envision that the postdoctoral scientist will play a major role in developing new projects in a supportive team science environment. To be considered for this role, please provide: 1) CV with a list of publications; 2) a short summary of your present and future research interests; 3) a list of three references and their contact information with your application. The ideal candidate will hold a PhD or MD-PhD, have prior research experience in any of the following: molecular biology, statistical genetics, biochemistry, computational biology and/or functional genomics and will have prior peer-reviewed publications. The candidate will be expected to plan and carry out research tasks independently and write-up/present findings on a regular basis. This position can be tailored to a candidate with strong molecular biology skills who are looking to improve their computational skills, or to a candidate with a stronger background in computational genetics or genomics looking to develop expertise in cutting-edge experimental methods. About NYGC: A cutting-edge environment for genomics NYGC is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer's, Parkinson's, Huntington's), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Salary The pay for this position is $88,000; this includes $70,000 base pay and an $18,000 per year taxable housing allowance. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. This includes Medical/Dental/Vision for employees & dependent(s); Vacation, Holidays, Sick, and Other Leave, including a paid winter break; a 401(k) match; Life Insurance; Flexible Spending Accounts; employee Tuition Reimbursement; flexible schedules and telework options for some positions; an Employee Assistance Program; and much more. Equal Opportunity We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive. We believe that bringing together individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery. Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success. We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are protected veterans and individuals with disabilities. FLSA Status - Exempt This position is eligible for visa sponsorship and relocation assistance.

WHO ARE WE Parse Biosciences is a global life sciences company whose mission is to accelerate progress in human health and scientific research. Empowering researchers to perform single cell sequencing with unprecedented scale and ease, our pioneering approach has enabled groundbreaking discoveries in cancer treatment, tissue repair, stem cell therapy, kidney and liver disease, brain development, and the immune system. With technology developed at The University of Washington, Parse has raised over $100 million in capital and is now used by over 3.000 customers across the world. Our growing portfolio of products includes Evercode Whole Transcriptome, Evercode TCR, BCR, Gene Capture, and Trailmaker, our data analysis solution. Parse Biosciences is based in Seattle, Washington's vibrant South Lake Union district, where we recently opened a 34,000 square foot headquarters and state-of-the-art laboratory. THE POSITION As a Technical Sales (Account) Manager, you will be responsible for achieving sales objectives for our single cell RNA sequencing products through the development of new business and management of current customer accounts. You will be expected to create and execute a sales strategy across academic, biotech, and pharmaceutical accounts while working closely with Field Application Scientists and other Parse team members. Candidates should have strong technical skills, sales skills, the ability to develop and manage customer relationships, and a drive to overachieve. Gaining a deep understanding of the single cell market and Parse's products will be critical to success. TERRITORY AND TRAVEL You will ideally be based in New York or Connecticut, and you will covering the following states: New York, Connecticut, Vermont, Maine, Rhode Island, and New Hampshire. The position will require travel approximately 50% of the time. IN THIS POSITION, YOU WILL • Generate and manage both high volume and large complex sales, • Ensure customers are satisfied and making rapid experimental progress, • Develop, maintain, and grow repeat business while maintaining strong relationships, • Prospect effectively to generate an immediate, medium, and long-term sales pipelines to ensure consistent quota obtainment, • Negotiate and close deals while minimizing discounting, • Effectively communicate technical advantages to customers, • Develop a quarterly and yearly business plan that incorporates both strategic and tactical activities, • Prioritize and qualify inbound leads, • Provide management with insight on competition, market trends, and customer feedback, • Manage your sales funnel with a high degree of accuracy, • Leverage expertise of Field Application Scientists to support customers and drive sales, • Leverage expertise of prospecting specialists to maximize customer meetings and drive new sales, • Use CRM to manage and track deals, • Continue to develop technical knowledge related to new, emerging, and related single cell research, • Forecast projected sales in your territory, • Bachelors in biology/genomics or a related field. A Masters or PhD is a plus, • Minimum of 3 years of relevant sales experience (preferably in either Next Generation Sequencing, genomics, or single cell analysis), • Previous molecular biology lab experience is preferred, • Excellent communication skills - written and verbal, • Ability and willingness to travel up to 50% of the time (locally, nationally, and internationally as needed), • Base salary + uncapped commission (commission paid quarterly), • 1st quarter commission guarantee for new hires, • Salary is based on a number of factors and may vary depending on job-related knowledge, skills, and experience, • Discretionary time off policy and Winter holiday break, • Monthly car allowance and internet and/cell phone stipend, • This position is home office based and will require a reliable internet connection and suitable workspace to fulfill job duties effectively., • Regular communication and collaboration with team members will occur virtually through zoom meetings, instant messaging, and email. As part of our commitment to fairness and inclusion, we do not use artificial intelligence or automated systems to screen job applications. Every application is reviewed by a member of our hiring team to ensure that hiring decisions are made thoughtfully and equitably. #LI-Remote To meet the health and wellness needs of our team, Parse offers a comprehensive benefits package for all full time employees, including: • Medical, dental, vision, and Rx (prescription) coverage beginning on the 1st day of the month following your start date. Parse covers 90% of the monthly premiums for employees, and 60% for dependents., • A 401(k) program with no waiting period to participate, • Basic life insurance and short and long-term disability coverage. Monthly premiums for both are covered at 100% by Parse., • Flexible spending account (FSA) options for medical, dependent care, and commuter expenses, • A transportation program (Seattle only), • 12 paid holidays annually and a winter holiday break $205,000 - $250,000 USD

Interested in exploring the role of adipose tissues in mucosal inflammation in a supportive, creative, and inclusive environment? The Grasset lab Our lab’s long-term objective is to uncover novel mechanisms underlying the pathology of Crohn’s disease (CD), a progressive incurable disease characterized by transmural intestinal inflammation leading to complications often requiring bowel resection surgery. The goal is to identify novel therapeutic targets by focusing on two previously disconnected hallmarks of CD: expanded mesenteric adipose tissue wrapping around the intestine – or creeping fat – and anti-microbial antibodies, both correlating with disease complications. Studying these hallmarks will further reveal unexplored relationships between adipocytes, stromal cells, and immune cells driving B cell responses in gut homeostasis and inflammation. Understanding these relationships will impact how we perceive immune responses at other mucosal sites and systemically. Ongoing projects include: the study of the impact of CD-specific microbiota on stromal cell-supported lymphoid structures embedded in mesenteric adipose tissue; specific mechanisms by which stromal cells and adipocytes communicate with B cells; and the subsequent impact on B cell activation and their differentiation to anti-microbial antibody-producing plasma cells. Future projects will investigate how these relationships are established in early life and evolve over time. Location The unique multidisciplinary and collaborative environment within the Drukier Institute for Children’s Health, the Department of Pediatrics, Division of Gastroenterology and Nutrition, and the Jill Roberts Institute for Inflammatory Bowel Disease provides an ideal setting to drive projects in our lab! You will join our lab on the Weill Cornell Medical College campus on the Upper East Side of Manhattan, at the heart of a research hub which includes Memorial Sloan Kettering Cancer Center and The Rockefeller University. This provides additional opportunities for collaboration and networking across multiple scientific disciplines. PI statement I believe the best way to foster a creative scientific environment is to reward teamwork while encouraging individuals to take on new challenges aligned with their individual development and project needs. Your career development matters and will be supported, including through seminar and conference presentations and grant-writing opportunities. Position Responsibilities We are seeking a team-oriented, collaborative, and proactive postdoc to play a key role in growing our research program. You would lead your own project focused on adipocyte–stromal–immune interactions in the context of Crohn’s disease and mucosal immunology, and collaborate with other lab members to maximize the use of our samples from gnotobiotic models and human tissues. Responsibilities include: · Conducting independent and collaborative research following lab, departmental, and institutional policies. · Designing, organizing, and executing experiments using established and new protocols. · Collecting, preparing, and analyzing research data; maintaining detailed experimental records. · Preparing datasets, figures, and statistical analyses for presentations and publications. · Participating in manuscript and abstract preparation, publishing research findings, and presenting at conferences. · Assisting the Principal Investigator with fellowship, grant, and scholarship applications. · Contributing to lab operations, including training or supervising students, interns, and other personnel. Minimum Qualifications · PhD, MD, or equivalent doctoral degree · Ability to work collaboratively, proactively, and effectively within a team · Strong written and verbal communication skills · Wet lab experience (e.g. molecular, cellular, and/or immunological techniques) · Mouse handling experience (e.g. colony work, bleeding, and/or in vivo experiments) Preferred Qualifications Experience in any of the following areas is highly valuable: • Adipocyte biology, • Fatty acid metabolism, • Adipose-derived stromal cells, • Stromal–immune crosstalk, • Immunology, • Microbiology Preferred technical experience includes: • Single-cell RNA sequencing analysis, • Spectral flow cytometry, • Confocal imaging (whole-mount clearing a plus), • B cell repertoire analysis, • Mass spectrometry, • Cell culture, • Anaerobic bacterial culture Application Process Interested applicants should email the following materials to Emilie Grasset at , using “Postdoc position” in the subject line: • CV, • Cover letter describing past and future research interests and motivation for applying to the Grasset Lab, • Following interviews, candidates will be asked to share the contact information of three references Weill Cornell Medical College offers subsidized housing, excellent benefits, and assistance with visa requirements. Commitment to Diversity Weill Cornell Medicine is committed to fostering a culture of diversity and inclusion among our faculty, staff, and students. We seek out individuals with a diverse range of backgrounds and experiences, and we work to create programs that support both our current employees and our recruitment efforts. EEO Statement Weill Cornell Medicine welcomes students, faculty, and staff with diverse backgrounds from across the globe to pursue world-class education and career opportunities, to further the founding principle of “any person, any study.” No person shall be denied employment on the basis of any legally protected status or subjected to prohibited discrimination involving, but not limited to, such factors as race, ethnic or national origin, citizenship and immigration status, color, sex, pregnancy or pregnancy-related conditions, age, creed, religion, actual or perceived disability (including persons associated with such a person), arrest and/or conviction record, military or veteran status, sexual orientation, gender expression and/or identity, an individual’s genetic information, domestic violence victim status, familial status, marital status, or any other characteristic protected by applicable federal, state, or local law. Appointment Term: One-year appointment, with potential for renewal based on performance and funding. Starting Date: Available immediately. The exact start date is flexible, with consideration for potential visa processing timelines. Lab and Department Websites: Lab: Drukier Institute: Department of Pediatrics: Salary: Salary is based on years of experience, starting at $74,692, and will comply with the Postdoctoral Union’s Collective Bargaining Agreement. Benefits: A summary of employee benefits can be found on the WCM Human Resources website. Visa Options: Candidates applying for this position could be eligible for a J-1 Exchange visitor visa and the H-1B temporary worker visa. Union Membership: This position is covered under a Collective Bargaining Agreement (CBA) between Weill Cornell Medicine and the International Union, United Automobile, Aerospace, and Agricultural Implement Workers of America (“UAW”), and its Local Union, Weill Cornell Medicine Postdocs United-UAW Local 4100.

The Genomics AI Program Manager will support a Center-wide Initiative at the New York Genome Center (NYGC) focused on advancing the development and application of artificial intelligence and machine learning approaches to genomic interpretation and human disease. The Initiative brings together NYGC faculty, technologists, computational scientists, and external collaborators to develop and apply large-scale AI models that link genomic sequence to cell-type-specific regulation, disease phenotypes, and biological function. The mission of the Genomics AI Initiative is to address key bottlenecks in genomic interpretation by integrating high-throughput sequencing, single-cell and spatial multiomics, perturbation and functional genomics, and modern machine learning approaches. This effort is inherently interdisciplinary and collaborative, requiring close coordination across scientific domains, data production and infrastructure, and external collaborative partners. Position Description The Program Manager will provide coordination and operational leadership across the full range of activities undertaken by the Genomics AI Initiative. This includes day-to-day management of complex, multi-investigator scientific collaborations; coordination of Consortium-wide activities such as working groups, journal clubs, and symposia; development of scientific and programmatic materials; and support for grant and philanthropic proposal development. The Program Manager will play a central role in enabling collaboration across NYGC leadership, faculty, Genomics AI fellows, external collaborators, and commercial partners by tracking scientific progress, facilitating data access and sharing, supporting computational infrastructure planning, and ensuring alignment across teams. This position will report to the Scientific Director & CEO, or an individual designated by the Scientific Director & CEO, and will work closely with the Genomics AI Initiative participants. This role sits at the intersection of genomics, data science, and program coordination and is well-suited for an incumbent adept at working across scientific disciplines and operational functions. Key Responsibilities Genomics AI Program Management * Manage and coordinate the scientific projects and collaborative activities of the Genomics AI Initiative in alignment with the goals and timelines; * Support Genomics AI Initiative leadership in organizing and running working groups, steering committee meetings, journal clubs, workshops, and symposia; * Track scientific objectives, milestones, action items, and dependencies across participating labs and teams, and regularly communicate progress to the Genomics AI Initiative leadership; * Coordinate the development, review, and dissemination of relevant materials, including presentations, reports, white papers, and scientific summaries; * Support development of grant applications, philanthropic proposals, and progress reports in collaboration with faculty, Research Administration, and Development; * Facilitate communication across Genomics AI Initiative participants to ensure alignment, transparency, and efficient collaboration; and * Organize meetings, prepare agendas and briefing materials, record meeting notes, and track follow-up actions. Data, Infrastructure, and Computational Coordination * Coordinate data sharing, access, and staging across NYGC teams and external collaborators, in partnership with Informatics, IT, and Data Engineering groups; * Work with NYGC's compliance officers and DARB to ensure that data usage is compliant and maintain a list of approved datasets as they relate to AI model development; * Serve as a liaison between scientific teams and operational groups to support troubleshooting related to data availability, compute usage, workflows, and analysis pipelines; and * Track dataset access and usage, benchmarking activities, and model development milestones across projects. Genomics AI Initiative Operations and Engagement * Support onboarding and coordination of Genomics AI Fellows and participating researchers; * Support development of inter-institutional workflows and agreements, including data access and use, collaboration, etc.; * Develop and manage annual budgets for Genomics AI Initiative activities and related grant proposals, and monitor expenditures throughout the year to ensure fiscal responsibility and alignment with program priorities; * Assist with planning and execution of scientific events and external engagement activities; * Help maintain strong working relationships among NYGC faculty, fellows, staff, and external partners; and * Contribute to long-term planning for the growth, sustainability, and evaluation of Genomics AI Initiative. Please note that this job description is not designed to cover or contain a comprehensive listing of activities, duties, or responsibilities required of the employee for this job. Duties, responsibilities, and activities may change. Position Requirements * Advanced degree (PhD, MS, or equivalent) in genomics, computational biology, data science, bioinformatics, or a closely related field; * 2+ years of project or program management experience in a scientific or research environment; * Demonstrated ability to understand and communicate complex scientific concepts across disciplines; * Experience working with large datasets, computational workflows, or data-intensive research programs preferred; * Strong organizational and time management skills, with the ability to manage multiple projects and priorities simultaneously; * Excellent written and verbal communication skills, including experience preparing scientific or technical materials; * Ability to work effectively cross-functionally at all levels, including with faculty, trainees, engineers, administrators and institutional partners; * Comfort operating in a fast-paced, evolving research environment with shifting priorities; * High degree of Initiative, judgment, and attention to detail; and, * Ability to work both independently and collaboratively as part of a team. Don't meet every single requirement? At NYGC, we are dedicated to building a diverse, inclusive, and authentic workplace, so if you're excited about this role but your past experience doesn't align perfectly with every qualification in the job description, we encourage you to apply anyway. You may be just the right candidate for this or other roles. Competencies * Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments. * Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so. * Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes Initiative and is solution-oriented; engages in work with passion and curiosity. * Leader and Manager: Attracts, develops and retains diverse talent to achieve outstanding results; encourages professional development, coaches and regularly communicates expectations and feedback; aligns and inspires efforts toward our mission; translates organizational vision into action; responsibly utilizes NYGC's human and financial resources to ensure organizational and financial health; uses good judgment when making decisions; pushes boundaries and generates new ideas. Work Location This position is based onsite at NYGC on a full time basis. Salary The pay range for this position is $110,000 - 130,000 per year; base pay offered may vary depending on job-related knowledge, skills, and experience. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. About the New York Genome Center The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the-art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer's, Parkinson's, Huntington's), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Equal Opportunity We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive. We believe that bringing together individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery. Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success. We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are protected veterans and individuals with disabilities. FLSA Status - Exempt This position is not eligible for visa sponsorship This position is not eligible for relocation assistance

The Director of Molecular Diagnostics serves as the CLIA Laboratory Director for NYGC's clinical molecular diagnostics laboratory. This role provides clinical and scientific leadership for a CLIA-certified, CAP-accredited laboratory performing next-generation sequencing (NGS)-based genetic and oncology testing. The Director is responsible for the clinical validity, regulatory compliance, and operational excellence of all laboratory testing activities. This includes oversight of assay development and validation, quality management systems, regulatory compliance, personnel competency, and clinical interpretation and reporting of molecular diagnostic tests. The Director ensures compliance with CLIA, New York State Department of Health (NYS CLEP), CAP, and other applicable federal and state regulations, including licensure requirements for laboratories providing testing services across multiple U.S. states. Job Responsibilities: Laboratory Leadership and Oversight * Provide scientific, clinical, and regulatory oversight for all molecular diagnostic testing operations at NYGC. * Ensure the laboratory operates in full compliance with CLIA, NYS CLEP, CAP, and other applicable regulatory standards. * Maintain active oversight of laboratory operations through regular presence and engagement with laboratory staff. Assay Development and Validation * Lead the development, validation, and implementation of next-generation sequencing (NGS)-based diagnostic assays for constitutional genetics and oncology. * Review and approve validation protocols, validation summaries, and performance characteristics for all new and modified assays. * Ensure validation of both FDA-approved/cleared platforms and laboratory-developed tests (LDTs) in accordance with regulatory standards. Quality Management and Compliance * Oversee the laboratory Quality Management System (QMS) including QA/QC programs, instrument maintenance records, and performance monitoring. * Direct implementation and management of proficiency testing programs for genetic and oncology assays. * Ensure ongoing compliance to maintain: * New York State certification (Genetic Testing; Molecular Oncology - Tumor and Cellular Markers) * CAP accreditation * CLIA certification * Lead continuous quality improvement initiatives and participate in monthly quality assurance meetings. * Oversee applications and maintenance of state laboratory licenses for laboratories providing testing services across multiple U.S. states. * Participate in CLIA, CAP, and institutional working groups or committees as appropriate. Clinical Interpretation and Reporting * Provide professional interpretation, review, and sign-out of molecular diagnostic test results. * Ensure test reports meet clinical, regulatory, and laboratory standards. * Serve as a resource for clinical consultation with ordering physicians and healthcare providers. Personnel Oversight * Supervise laboratory personnel and ensure appropriate training, competency assessments, and continuing education. * Ensure laboratory staffing and qualifications meet regulatory requirements. This person must maintain sufficient on-site presence to provide effective oversight of laboratory operations. They must also be available for personal, telephone, or electronic consultation with laboratory personnel and clients. Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities, and activities may change. Position Requirements: * MD or PhD in molecular biology, genetics, or a related field. * Board certification in an appropriate specialty (e.g., Clinical Molecular Genetics and Genomics or Molecular Genetic Pathology). * Possession of New York State Certificate of Qualification (CQ) in Genetic Testing required. Additional NYS Certificates of Qualification (e.g., oncology, infectious disease) preferred. * Minimum 5 years of leadership experience in a molecular diagnostics laboratory, including oversight of clinical NGS testing and laboratory personnel. * Demonstrated expertise in molecular diagnostics assay validation, regulatory compliance, and quality systems. * Experience directing laboratories performing constitutional genetic testing and molecular oncology testing preferred. * Experience managing laboratories licensed in multiple U.S. states preferred. Don't meet every single requirement? At NYGC we are dedicated to building a diverse, inclusive and authentic workplace, so if you're excited about this role but your past experience doesn't align perfectly with every qualification in the job description, we encourage you to apply anyway. You may be just the right candidate for this or other roles. Competencies * Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments. * Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so. * Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity. * Leader and Manager: Attracts, develops and retains diverse talent to achieve outstanding results; encourages professional development, coaches and regularly communicates expectations and feedback; aligns and inspires efforts toward our mission; translates organizational vision into action; responsibly utilizes NYGC's human and financial resources to ensure organizational and financial health; uses good judgment when making decisions; pushes boundaries and generates new ideas. Work Flexibility NYGC has established a flexible work policy to give employees and other staff more ability to balance their work, personal commitments, and commuting challenges. The incumbent in this position is eligible for a flexible work schedule or hybrid remote work arrangement with supervisory approval. It requires a minimum of two days per week onsite. Occasional evening and weekend work may be required. Salary & Benefits The pay range for this position is $300,000-320,000 per year; the base pay offered may vary depending on job-related knowledge, skills, and experience. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. This includes Medical/Dental/Vision for employees & dependent(s); Vacation, Holidays, Sick, and Other Leave, including a paid winter break; a 401(k) match; Life Insurance; Flexible Spending Accounts; employee Tuition Reimbursement; flexible schedules and telework options for some positions; an Employee Assistance Program; and much more. About the New York Genome Center The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer's, Parkinson's, Huntington's), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Equal Opportunity We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive. We believe that bringing together individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery. Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success. We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are protected veterans and individuals with disabilities. FLSA Status - Exempt This position is eligible for visa sponsorship and relocation assistance

The Satija lab at the New York Genome Center is looking for an enthusiastic and highly motivated senior computational biologist. We encourage applications from talented scientists who are interested in gaining experience in a multidisciplinary, international, and dynamic research environment. The successful candidate will supervise and work closely to PhD students, postdoctoral fellows, and computational biologists in the lab to develop new statistical methods and software for the analysis of single cell datasets. This is an exciting opportunity to learn about the latest developments in the growing space of single cell genomics while contributing to new research in cancer immunology and developmental neuroscience. Job duties will include: • Develop computational methods to analyze single-cell genomics datasets;, • Contribute to the codebase, development, and support of open-source software packages;, • Assist in data analysis and interpretation for diverse research projects;, • Help to manage lab servers and computational infrastructure; and,, • Document and present results in written or oral reports to other lab members., • PhD or MS degree in bioinformatics, computer science, biology, biochemistry or similar;, • Excellent programming skills, for example, in R, Python, and BASH;, • Experience working in a Linux environment;, • Team oriented with excellent written and verbal communication skills;, • Training in statistics or machine learning preferred;, • Exposure or training in NGS data analysis, functional genomics and/or human genetics preferred. Salary The salary range for this position is $100,000-120,000 per year. Base pay offered may vary depending on job-related knowledge, skills, and experience. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. Competencies • Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments., • Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so., • Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity. About the New York Genome Center The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer's, Parkinson's, Huntington's), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with twelve leading academic medical centers and research universities in the New York region and beyond, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Equal Opportunity We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive. We believe that bringing together individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery. Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success. We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are, protected veterans, and individuals with disabilities. FLSA Status - Exempt This position is eligible for visa sponsorship and relocation assistance.

Job details About Us: The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursueour missionat MSK and around the globe. Lab or Department & Position Overview The Chan Lab in the Human Oncogenesis & Pathogenesis Program at Memorial Sloan Kettering Cancer Center is seeking a highly motivated and successful computational postdoctoral fellow to study the mechanisms and therapeutic implications of tumor cell plasticity. Our lab in translational computational oncology integrates single-cell and spatial genomics, cell-free DNA profiling, and machine learning to understand how tumors evolve under therapeutic and microenvironmental pressures. We leverage large, deeply annotated patient cohorts with longitudinal sampling, tightly coupled with functional preclinical models, to enable discovery and validation of mechanisms of tumor evolution. A central focus is lineage plasticity, the ability of cancer cells to transition between phenotypic states, which underlies metastasis, immune evasion, and drug resistance. Current research directions include: * Defining transcriptional and epigenetic programs that drive lineage plasticity across adenocarcinoma, squamous, and neuroendocrine states in solid tumors * Investigating analogous mechanisms of lineage switching in hematologic malignancies, including Richter's transformation and myelofibrosis. * Mapping immune and treatment-induced pressures that shape cell fate decisions across space and time * Building predictive computational models of lineage transformation and therapeutic resistance through multi-modal data integration (scRNA-seq, ATAC-seq, spatial imaging, lineage tracing, cfDNA) This position offers the opportunity to work with deeply annotated patient cohorts, longitudinal samples, and cutting-edge experimental systems in a highly collaborative environment. We are seeking individuals who bring creativity, intellectual curiosity, and a strong drive to uncover underlying mechanisms, with a clear motivation to translate discoveries into improved patient care. Responsibilities include developing and applying computational methods, biological interpretation, assisting or leading in manuscript writing, engaging in a vibrant scientific community through regular work-in-progress and lab meetings, and other academic activities. For more information, please visit the lab website at ___. Candidate Requirements The ideal candidate should have: * A PhD in Computational Biology, Bioinformatics, Computer Science, Statistics, or a related field * Proficiency in Python and R * Prior experience in computational biology * Ability to engage in independent thinking * Excellent skills in written and verbal communication * Collegiality as a team member and a willingness to mentor other trainees * At least 1 published first-author manuscript Required: Application Submission Details If you have any questions about this job opportunity, please contact: Dr. Joseph M. Chan, MD, PhD Please include a cover letter, brief statement of prior research experience and research interests, CV, and contact information for three references in your application submission. Salary Range Salary: $72,000-$87,000 (depending on postgraduate experience) Pay Range: $0.00 - $10,000,000.00 FSLA Status: Exempt Closing: At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills. MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

Job details About Us: The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursueour missionat MSK and around the globe. The Chandarlapaty lab is comprised of a multidisciplinary team investigating the basis for therapeutic response and resistance in breast cancer. *A postdoctoral research position is opening to specifically study the mechanisms underlying the response of homologous recombination deficient (HRD) breast cancers to endocrine therapies • The project will involve development and validation of high-fidelity models of endocrine-responsive HRD breast cancer using advanced genome engineering approaches of both 2D and 3D culture systems, as well as molecular and functional assays related to DNA damage and repair and endocrine therapy response and resistance., • The successful candidate will be required to work in collaboration with other members of the laboratory as well as several clinical and translational teams with shared interests., • Position is supported by funding from the National Cancer Institute and the Breast Cancer Research Foundation Key Requirements: * PhD in cancer biology, genetics, cell biology, or pharmacology. * Track record of publication in areas of cancer biology, genetics, cell biology, or pharmacology. * Demonstrated ability to design, execute and interpret experiments independently. * Ability to work collaboratively in a multidisciplinary team environment. Application Requirements Core Skills: * Strong expertise with mammalian cell culture and genetic manipulation * Demonstrated expertise in CRISPR/Cas9 genome editing * Solid background in molecular biology techniques (PCR, western blot, sequencing based validation) * Experience with organoid culture or other 3D model systems preferred * Bioinformatics experience for analysis of sequencing or functional genomics data preferred * Interest in translational research and collaboration with clinical teams Application Instructions Submit C.V., letter of interest, and references in your application submission to:Sarat Chandarlapaty, MD, PhD Pay Range: $72,000 - $96,405 Helpful links: Pay Range: $0.00 - $10,000,000.00 FSLA Status: Exempt Closing: At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills. MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

Job details About Us: The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursueour missionat MSK and around the globe. The ___, a multi-R01 funded research program, in conjunction with the Druckenmiller Center for Lung Cancer Research, is searching for an outstanding post-doctoral candidate with a strong interest in translational research focused on the biology of lung cancer metastases. The Jones laboratory focuses on transcriptomic and genomic drivers of lung and esophageal cancer metastases. Other projects in the laboratory include leveraging a large, genomically annotated patient-derived organoid program (lung and esophageal cancer), and identification of new genomic predictors of lung cancer recurrence, among others. We are seeking candidates with a strong molecular and tumor biology background with experience in lung cancer tumor biology, immunology, xenograft and transgenic animal models of metastases, and the biology of metastases. The candidate will have the opportunity to interact with investigators with expertise in the biology of lung cancer, translational therapeutics, and molecular pathology. The ideal candidate should have: * PhD or equivalent in biological science * Proficient in major types of tumor mouse models * Experience with genomic or transcriptomic data analyses is desirable * Ability to work independently and collaboratively in a multidisciplinary environment Additionally Information Please send CV, bibliography, brief statement of research interests and names of 3 references via email (Including #JonesResearch in the subject line) to: Russell Holmes Surgery Research Lab Manager, SKI Salary: 72,000-100,000 Pay Range: $0.00 - $10,000,000.00 FSLA Status: Exempt Closing: At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills. MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

The Department of Pathology and Cell Biology at Columbia University is seeking a Director of Hematopathology at the Associate Professor or Professor level. Board certification in Anatomic Pathology and certification or eligibility in Hematopathology are requirements for this position. Teaching and communication skills are essential. Applicants must hold an MD, DO, or MD/PhD degree and be able to obtain a NYS medical license. At CUIMC, we stand together because diverse experiences, perspectives, and values enrich every dimension of our work. Join our team and see how your unique skills and experiences can create a real impact by changing lives. Key Responsibilities: * • Provide expert diagnostic services in hematopathology., • Oversee and manage hematopathology laboratory operations, ensuring compliance with regulatory standards., • Lead and mentor faculty, trainees while contributing to education through teaching of residents, and fellows., • Collaborate with clinical teams to support patient care and multidisciplinary initiatives. Qualifications: * • MD, DO or MD/PhD (or equivalent medical degree)., • Board certification in Anatomic and/or Clinical Pathology (AP/CP) with subspecialty certification in Hematopathology (American Board of Pathology), • Eligibility for medical licensure in the State of New York., • Excellent interpersonal and communication skills, and a collaborative approach to multidisciplinary care. Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Department of Pathology and Cell Biology at Columbia University is seeking a full-time hematopathologist at the Assistant or Associate Professor level. Board certification in Anatomic Pathology and certification or eligibility in Hematopathology are requirements for this position, and subspecialty training in molecular pathology is preferred. Teaching and communication skills are essential. At CUIMC, we stand together because diverse experiences, perspectives, and values enrich every dimension of our work. Join our team and see how your unique skills and experiences can create a real impact by changing lives. The compensation range does not include the generous benefits program, and there is significant potential for additional incentive payments based on productivity and quality measures. Minimum Degree Required: M.D., D.O., or M.D./Ph.D. Applicants must hold an MD, DO, or MD/PhD degree and be able to obtain a NYS medical license. Minimum Qualifications: Depending on the field of research and current needs for field and instructional coverage within the department, certain subspecialties may be preferred. Current research specialties: Cancer Biology, Neurodegenerative Diseases, Cellular and Molecular Neurobiology, Cell Motility, Cytoskeleton and Intracellular Trafficking, Virology, Neuronal Stem Cells, Precision Medicine, Clinical or Anatomic subspecialties. Preferred Qualifications: Depending on the field of research and current needs for field and instructional coverage within the department, certain subspecialties may be preferred. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Staff Scientist will prepare grant applications and other scientific communication materials on a wide range of genomic research topics. This role is deeply immersed in the science of NYGC and supports our research team in building and expanding a successful, independently-funded research base. They collaborate with diverse teams of students, postdoctoral fellows, and principal investigators, and relates scientific and strategic goals to individual grant opportunities and other research communications vehicles. Typical grants include individual investigator, multi-PI and research center grants. Key Responsibilities • Takes a lead role in preparation and project management of individual and multi-investigator proposals;, • Manages the scientific writing process, including proposal management, team-building and coordination; establishing timelines and deliverables;, • Provides draft preparation, review and revision of grants and scientific writing., • Coordinates with and supports Sponsored Research staff to ensure timely, accurate application submission., • Edits manuscripts, fellowship applications, research progress reports, clinical research protocols and other research communications materials., • Interacts with lab members to independently develop new grant proposals., • Organizes small group meetings with lab members to review project progress, plan experiments, and integrate team data., • Assists in the design and planning of functional genomics and genetic perturbation experiments; and,, • Exceptional written communication skills required to prepare and edit competitive grant applications, publications, administrative materials, and other research communications;, • Ability to grasp complicated technical subjects, synthesize diverse lines of evidence and apply these abilities to technical writing required;, • Experience handling the scientific writing and project management process for multi-investigator and institutional grant applications strongly preferred;, • Experience with standard grant development concepts, practices, and procedures in a research environment preferred;, • Applied statistics background required, to perform power calculations and develop quantitative metrics for genomic assays;, • Ability to collaborate with diverse teams of investigators and administrative personnel required; and,, • Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations, and delivers on commitments., • Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so. The salary range for this position is $62,000-78,000 per year. Base pay offered may vary depending on job-related knowledge, skills, and experience. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. About the New York Genome Center The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer's, Parkinson's, Huntington's), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Equal Opportunity We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive. We believe that bringing together individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery. Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success. We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are protected veterans and individuals with disabilities. FLSA Status - Exempt This position is eligible for visa sponsorship and relocation assistance.

The Satija lab at the New York Genome Center is looking for an enthusiastic and highly motivated computational biologist. We encourage applications from talented scientists, who are interested in gaining experience in a multidisciplinary, international, and dynamic research environment. The successful candidate will work closely to PhD students, postdoctoral fellows, and computational biologists in the lab to develop new statistical methods and software for the analysis of single cell datasets. This is an exciting opportunity to learn about the latest developments in the growing space of single cell genomics while contributing to new research in cancer immunology and developmental neuroscience. Job duties will include: • Develop computational methods to analyze single-cell genomics datasets, • Contribute to the codebase, development, and support of open-source software packages, • Assist in data analysis and interpretation for diverse research projects, • Help to manage lab servers and computational infrastructure, • Document and present results in written or oral reports to other lab members About the Satija Lab Dr. Satija's lab studies the causes and consequences of cellular heterogeneity in complex biological systems. His group is particularly interested in single cell genomics, with active development in both the dry and wet lab. The lab integrates novel statistical and machine learning-based methods with experimental analysis in order to better understand how cells work together to drive biological processes and behaviors. • BS or MS degree in bioinformatics, computer science, biology, biochemistry or similar;, • Excellent programming skill, for example, in R, Python, and BASH;, • Experience working in a Linux environment;, • Team oriented with excellent written and verbal communication skills;, • Training in statistics or machine learning preferred;, • Exposure or training in NGS data analysis, functional genomics and/or human genetics preferred. Competencies • Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments., • Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so., • Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity. Salary The salary range for this position is $65,000-85,000 per year. Base pay offered may vary depending on job-related knowledge, skills, and experience. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. About the New York Genome Center The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer's, Parkinson's, Huntington's), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with twelve leading academic medical centers and research universities in the New York region and beyond, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Equal Opportunity We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive. We believe that bringing together individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery. Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success. We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are, protected veterans, and individuals with disabilities. FLSA Status - Exempt This position is eligible for visa sponsorship and relocation assistance.

The Zeltser lab is looking for a motivated scientist to join their team as an Assistant Professor of Medical Sciences in Medicine at the Columbia University Medical Center (non-tenure track). The lab studies how the sympathetic nervous system regulates metabolism and how this is impacted by obesity and aging. We utilize a variety of genetically engineered mouse models, virus-based neural tracing and chemogenetic approaches, single nuclear transcriptomics, and in vivo physiological and metabolic measurements. The ultimate goal is to identify neural circuits that regulate distinct aspects of brown fat and function and systemic metabolism. The ideal applicant will be an experienced researcher with expertise in both neuroanatomy and the neurobiology of autonomic regulation of peripheral targets and/or central regulation of metabolic parameters. The procedures for this project require expertise in multiple advanced techniques. The experienced researcher must be able to master state-of-the-art techniques to map and manipulate sympathetic circuits regulating discrete targets in the periphery, including stereotaxic injections, viral tracing, chemogenetics and fiber photometry. In parallel, this project also involves the analysis of physiological phenotypes in vivo, including thermogenesis, glucose uptake and lipolysis. Experience with surgical techniques in mice is essential. The applicant will be expected to lead projects independently and to train and mentor others. The applicant is also expected to make substantive contributions to the formulation and writing of manuscripts and grant applications. Interest in developing new technologies is a plus. Responsibilities: • Perform daily lab activities to carry out research projects in the lab., • Perform basic neuroanatomical assays including mounting and immunohistochemical staining in sections, clearing and immunostaining in intact brains, and imaging using confocal and light sheet microscopy., • Perform physiological and metabolic assays in mice., • Perform surgeries in mice to inject compounds and to implant devices in the brain and the periphery., • Train and mentor others., • Contribute to the formulation of grant applications, primary research papers and review articles., • Minimum Qualifications: Applicants should have a PhD, MD or MD/PhD in Cellular Biology with at least 5 years of postdoctoral experience. Excellent oral and written communication skills, a strong work ethic, and the ability to work independently are essential. Well-versed with molecular biology and basic techniques to measure mRNA and protein. Proficient at performing complicated experiments in a timely manner. Ability to work independently and collaboratively. Willingness to work with mice. Technical accuracy, reliability, and attention to the details of procedural protocols, organizational skills, adherence to safety guidelines and the ability to work in a team. Excellent organizational skills and a strong interest in biological sciences. Preferred Qualifications: Experience in leading a group is preferred. Experience in mouse handling and colony maintenance highly preferred. Experience in basic histological procedures (i.e. immunohistochemistry and in situ hybridization) is preferred but not essential. Experience in mouse surgical procedures is preferred. Experience with R is preferred but not essential. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The College of Dental Medicine (CDM) at Columbia University is searching for a full-time tenure track open-rank research faculty in Data Science and one of the following fields: Bioengineering, Systems Biology, or Orally Related Diseases. Reporting to the Section Chair, the Data Science - CDM faculty are expected to develop, sustain, and lead an active, obvious, externally funded research program with outstanding scholarship and to demonstrate excellence in teaching and mentoring students at all levels including those in our DDS/PhD program. The candidate will collaborate closely with the Data Science Institute. A successful candidate will have demonstrated evidence of scholarly impact through publications and the potential to conduct pioneering research, obtain funding support, and collaborate, teach, and mentor effectively. In addition to technical and scientific knowledge, the candidate of choice will have excellent organizational and interpersonal skills, and thrive in a collaborative, fast-paced, and multi-disciplinary research setting. Our top-tier research institution provides extensive opportunities for collaborations across the university and medical center and collaborations with fellow researchers within CDM. Ph.D. in cancer biology, microbiology, immunology, systems biology, bioengineering, computational biology, computer science, applied math, or dental and medical degree with equivalent research experience. Academic rank and salary commensurate with qualifications and experience. Women and minorities are particularly encouraged to apply. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Institute of Human Nutrition (IHN) in collaboration with the Department of Physiology and Cellular Biophysics at Columbia University in the City of New York, seeks candidates for Assistant Professor in the tenure track. The IHN fosters a network of researchers at the cutting edge of their disciplines, all working together to advance the fields of nutritional and metabolic biology. Applicants must have a Ph.D. and/or M.D./Ph.D. or equivalent degree, an outstanding record of research accomplishments showing high level of productivity in their field and the potential to secure external funding and excellent teaching credentials. The successful candidate will use cutting edge technologies in the field of cellular, tissue and organismal metabolism in physiological and pathological conditions. Responsibilities include establishing a rigorous and independently funded research program in metabolic biology, supervising and mentoring students with diverse background. Successful candidates will be expected to participate in the teaching and mentoring of Masters students and PhD students within the IHN as well as other graduate training programs. All recruited IHN faculty will be fully supported by a structured mentoring and career committee. Successful candidates will be appointed to the Department of Physiology and Cellular Biophysics within the Vagelos College of Physicians & Surgeons (VP&S) of Columbia University Irving Medical Center (CUIMC) and Columbia University (CU). They will be an integral part of a highly collaborative group of faculty working in a broad range of areas related to metabolism. Faculty in IHN are associated with the Graduate School of Arts and Sciences, and may have membership in other Institutes and Centers, including the Herbert Irving Comprehensive Cancer Center, the Naomi Berrie Diabetes Center, Columbia Stem Cell Initiative, and the Taub Institute, and have the opportunity to interact with faculty at Columbia University's Morningside and Manhattanville Campuses. Minimum Degree Required: • Ph.D. and/or MD degree Minimum Qualifications: • Must demonstrate the ability to develop an internationally recognized extramural funded research program. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

Senior Staff Associate I position available July 1, 2026 in a leading laboratory investigating host-pathogen interactions. Self-motivated individual with a strong background in one or more areas of microbiology, cell and molecular biology, and biochemistry are encouraged to apply. Master's degree is required. PhD or equivalent combination of education and experience preferred. At least five years of wet lab research experience preferred. Candidates should demonstrate excellent scientific vigor, critical thinking, written and oral communication skills, and ability to work independently and collaboratively in a multidisciplinary team. Experience with rodents is a plus, but not required. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Department of Surgery at Vagelos College of Physicians and Surgeons accepting applications for a Postdoctoral Research Scientist in the Department of Surgery, Division of Surgical Sciences. The individual will train under the supervision of Dr. Giovanni Ferrari in the development of Implantable Biomaterials in pediatric patients and participation in the Heart Perfusion Research Program. Responsibilites: • Train in cell culture, flow cytometry, fluorescence-activated cell sorting, polymer processing., • Train in the technical skills of data collection, statistical analysis and manuscript writing., • Present research results and prepare manuscripts for peer review and publication in professional journals., • Perform literature searches, manage data, analyze experimental results and published data., • Participate in the development of an extramurally funded research program by assisting PI with NIH grant by developing and generating data and figures., • Provide expertise and input on collaborative grant proposals., • Participate in clinical outcome research in the field of study., • Other activities as assigned related to the research program of Dr. Ferrari., • Species contact includes pigs, rodents , and mice including animal blood & bodily fluids., • Potential exposure to bloodborne pathogens, infectious agents and biological toxins., • Experience in research projects related to heart valves and/or aortic diseases, Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Department of Pathology and Cell Biology at Columbia University Irving Medical Center seeks a highly qualified Postdoctoral Research Fellow to develop, validate and run High Resolution Mass Spectrometry-based quantitative drug and exposomics assays in support of the care of patients with obesity and diabetes and in support of patients with psychiatric disorders. The ARPA-H funded project is part of a multi-institutional effort (IndiPHARM) led by Dr Gary Miller from Columbia University, Mailman School of Public Health. The project itself is led by Drs Serge Cremers, and Alex Lyashchenko who will be overseeing the activities of the fellow in the Clinical Pharmacology and Toxicology Laboratory of the Department of Pathology and Cell Biology at Columbia University Irving Medical Center. The work is to lead to several scientific publications and will provide a unique opportunity for clinical pathologists and clinical chemists to gain experience in the development of highly complex mass spectrometry assays and their application in patient care. For other MDs, PhDs, and/or PharmDs with experience in this area, the work not only provides a unique opportunity to develop highly complex mass spectrometry assays for patient care, but also an opportunity to be trained as clinical laboratory director and clinical pharmacologist. Job Function: Develop, validate and implement High Resolution Liquid Chromatography Mass Spectrometry (Exploris-120)- based panel assays to quantify drugs, metabolomic and exposomic markers in blood of patients in support of their care. The panel assays are to be approved for patient care by NY State Department of Health. The panels are focused on drugs, metabolomic, and exposomic markers relevant for treatment patients with diabetes and obesity and for the treatment of patients with psychiatric diseases. The development of the assays will take place in close collaboration with the other investigators involved in the IndiPHARM project, especially Drs Gary Miller and Randolph Singh's group from Columbia's Mailman School of Public Health and Dr Douglas Walker from Emory University. The fellow will be involved in the clinical pharmacological interpretation of these highly complex assays for individual patients and is expected to publish several papers from these activities. If eligible, the fellow is expected to apply for a Laboratory Director Certificate of Qualification in Therapeutic Substance Monitoring / Quantitative Toxicology from New York State Department of Health. Lab Mission/Purpose: The Clinical Pharmacology and Toxicology Laboratory of the Department of Pathology and Cell Biology is a state-of-the-art CLIA-, CAP, and New York State Department of Health-accredited academic clinical laboratory that develops and offers LC-MS- and HPLC-based assays for drugs in support of patient care. The laboratory's rapidly expanding test menu includes routine assays for drugs that are also offered by other clinical laboratories but its primary focus is on drugs for which therapeutic drug monitoring is not available anywhere else. In addition, the laboratory's unique position within one of the world's leading medical centers enables early translation of assays for drugs in development into patient care. Assays are developed and offered for patient care in close collaboration with academic research groups as well as pharmaceutical and diagnostic companies. In addition to reporting drug levels, the laboratory provides consults with respect to the interpretation of drug levels using pharmacokinetic software and integrating chemistry, clinical, and genetic data into the therapeutic drug monitoring process. Minimum Education Requirements: MD, PharmD, and/or PhD Minimum Skills Required: Experience in developing and validating assays with LCMS, preferably with an Orbitrap. Preferred Qualifications: Clinical Pathologist Clinical Chemist Clinical Pharmacologist (ABCP) Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Opportunity This opportunity to join the Department of Pediatrics at the Vagelos College of Physicians and Surgeons at the rank of Associate Research Scientist with the Division of Cardiology is an exciting one. Columbia University Irving Medical Center, one of the nation's foremost academic health science centers. The Department of Pediatrics at Columbia University Irving Medical Center is the top in comparison with other pediatrics department in the NY region in NIH research funding. The primary focus of the Targoff Lab is to investigate the molecular and cellular mechanisms underlying cardiovascular development and regeneration. We accomplish these goals through the use of zebrafish as a model system and expand our studies into the fields of transcriptional regulation, cardiac mechanobiology, and stem cell biology. We utilize an innovative combination of genetic, live-imaging, single cell genomic, and transgenic approaches. We seek an energetic and inquisitive scientist who will work in a highly collaborative environment and who demonstrates critical thinking and academic rigor. Outstanding and exceedingly motivated candidates with backgrounds in developmental biology, genetics, and molecular biology. Key Responsibilities • Perform molecular biological experiments., • Perform confocal imaging., • Perform transcripomic anaylsis., • Carry out fully planned experiments., • Manage animal colonies (zebrafish husbandry) and performing animal work., • Interpretation of data and keeping records of results., • Contribute to the preparation of reports and publications., • Participation in seminars, conferences, lab meetings, and grant writing. Columbia University is an Equal Opportunity/Affirmative Action Employer and Educator. The University is dedicated to the goal of building a culturally diverse and pluralistic faculty and staff committed to teaching and working in a diverse environment, and strongly encourages applications from women, minorities, individuals with disabilities, and veterans. Columbia University welcomes applications from individuals who may have had nontraditional career paths, or who may have taken time off for family reasons (e.g. children, caring for disabled or elderly family), or who have achieved excellence in careers outside of academia (e.g., in professional or industry service). The University is responsive to the needs of dual career couples and is committed to supporting the work-life balance of its faculty. We are interested in candidates who have a record of success advising and mentoring individuals from groups underrepresented in higher education and is particularly interested in candidates who have research interests in subjects that will contribute to the understanding of diversity and equal opportunity. • PhD in Epidemiology or Biostatistics or relevant area, • 2-3 years of postdoctoral training required (applicable only for rank of Associate Research Scientist), • Consistently strong interpersonal skills and the ability to build and sustain effective working relationships with professionals in other disciplines., • The ability to create a high-energy results-oriented work environment that encourages colleagues and staff to value each other's contributions. Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

THE OPPORTUNITY This opportunity to join the Department of Pediatrics at the Vagelos College of Physicians and Surgeons at the rank of Instructor is an exciting one. Columbia University Irving Medical Center, one of the nation's foremost academic health science center's working together with one of the nation's premier health systems, New York-Presbyterian Hospital. KEY RESPONSIBILITIES Columbia University College of Physicians and Surgeons and New York-Presbyterian Hospital are recruiting for a full-time academic pediatric faculty member in the Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation at the Instructor level on the non-tenure track. This position will be focused on laboratory-based research related to gene therapy for both malignant and non-malignant disorders. The successful candidate will have the opportunity to collaborate with the outstanding clinical and research faculty within the division and at the Columbia University Irving Medical Center, the NCI-designated Herbert Irving Comprehensive Cancer Center, the Mailman School of Public Health, and the Columbia Initiative in Cell Engineering and Therapy (CICET). Founded in 1959, The Division of Pediatric Hematology, Oncology, and Stem Cell Transplant at Columbia Children's Health, New York-Presbyterian Morgan Stanley Children's Hospital (MSCH) is one of the oldest and most comprehensive centers in the country focused on treating children with cancer and blood disorders. MSCH has 202 inpatient pediatric beds, including a 54-bed Pediatric Intensive Care Unit and 10 operating rooms. Our division is currently composed of 3 sections (Hematology, Oncology and Stem Cell Transplantation) with 21 full-time faculty, 4 research RN/NP's, 8 clinical research associates, and 3 regulatory specialists and includes an ACGME-accredited Fellowship Program and a FACT-accredited stem cell transplant program. The division is one of 21 institutions to serve as a core sire of the Children's Oncology Group Pediatric Early Phase Clinical Trials Network (PEP-CTN). It is also a member of the Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium. Research Responsibilities Laboratory-based research efforts will focus on the molecular biology of gene therapy for malignant and non-malignant diseases with the goal of include establishing a platform for tracking clonal expansion and monitoring transgene integration and expression in gene therapy trials, as well as participating in the development of novel strategies for the treatment of globin disorders. Research projects will be conducted under the mentorship of senior investigators at CUIMC and CICET, including Drs. Michel Sadelain (who will provide direct oversight and supervision of research projects), Max Mamonkin and Markus Mapara. It is expected that 80% effort will be devoted to laboratory-based research activities. Clinical Responsibilities Clinical responsibilities will include serving as attending physician on the inpatient stem cell transplantation service and providing outpatient care to children, adolescents and young adults who have undergone stem cell transplantation. In addition, the successful candidate will be expected to attend and participate in clinical stem cell transplantation meetings, as well as divisional and departmental clinical conferences. It is expected that 20% effort will be devoted to clinical activities. COMPENSATION Compensation arrangements are competitive and commensurate with both experience and achievement. COMMITMENT OF DIVERSITY Columbia University is an Equal Opportunity/Affirmative Action Employer and Educator. The University is dedicated to the goal of building a culturally diverse and pluralistic faculty and staff committed to teaching and working in a diverse environment, and strongly encourages applications from women, minorities, individuals with disabilities, and veterans. Columbia University welcomes applications from individuals who may have had nontraditional career paths, or who may have taken time off for family reasons (e.g. children, caring for disabled or elderly family), or who have achieved excellence in careers outside of academia (e.g., in professional or industry service). The University is responsive to the needs of dual career couples and is committed to supporting the work-life balance of its faculty. We are interested in candidates who have a record of success advising and mentoring individuals from groups underrepresented in higher education and is particularly interested in candidates who have research interests in subjects that will contribute to the understanding of diversity and equal opportunity. • Must have an MD, DO or PhD degree and an active NYS Medical License., • Must be Board certified/eligible in Pediatric Hematology/Oncology or an equivalent board certification with experience in the care of pediatric stem cell transplant patients, • Laboratory experience related to the field of gene therapy and/or cell therapy., • Consistently strong interpersonal skills and the ability to build and sustain effective working relationships with professionals in other disciplines. Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Department of Pathology and Cell Biology at Columbia University is seeking a Director of Surgical Pathology at the Associate Professor or Professor level. Board certification in Anatomic Pathology is a requirements for this position. Teaching and communication skills are essential. Applicants must hold an MD, DO, or MD/PhD degree and be able to obtain a NYS medical license. Key Responsibilities: • Provide expert diagnostic services in surgical pathology., • Oversee and manage laboratory operations, ensuring compliance with regulatory standards., • Lead and mentor faculty, trainees while contributing to education through teaching of residents, and fellows. Minimum Education Qualifications: • Board certification in Anatomic Pathology (AP) (American Board of Pathology)., • Eligibility for medical licensure in the State of New York., • Excellent interpersonal and communication skills, and a collaborative approach to multidisciplinary care. Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

Associate Research Scientist position available immediately in a leading laboratory investigating host-pathogen interactions. Self-motivated individuals with PhD degree or equivalent with a strong background in one or more areas of immunology, microbiology, cell and molecular biology, and cancer biology are encouraged to apply. PhD with at least five years of wet lab research experience. Candidates should have excellent publication records and demonstrate excellent scientific vigor and integrity, critical thinking, written and oral communication skills and ability to work independently as well as collaboratively in a multidisciplinary team. Experience with rodents is required. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

Job details About Us: The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursueour missionat MSK and around the globe. Join the Lee Lab: Cancer Genome History & Therapeutics at MSK. We study the mutational processes and genomic rearrangements that drive cancer evolution and therapy resistance using high-throughput sequencing as the main toolkit. We are seeking a highly motivated postdoctoral fellow with strong expertise in computational biology to lead projects at the interface of cancer biology, single-cell genomics, and clinical oncology. Project focus: You will analyze single-cell whole-genome sequencing data jointly with other multi-omic datasets from i) genetically engineered mouse models, ii) PDX/PDO systems, and iii) clinical tumor samples to define evolutionary trajectories of extrachromosomal circular DNA-mediated oncogene amplification. This position offers a unique opportunity to work in a highly collaborative and translational environment, closely partnering with experimental scientists and clinician investigators. The position is supported by a grant from the Burroughs Wellcome Fund. What you will do: * Lead computational analyses of high-throughput sequencing datasets, including scWGS and multi-omic datasets * Apply/adapt/develop novel computational approaches to study mutational processes, structural variation, and clonal evolution in cancer * Collaborate on experimental design and interpretation with wet-lab and clinical teams. * Integrate genomic data with rich clinical annotation to uncover biologically and clinically meaningful insights * Drive preparation of high-impact manuscripts and present findings at major conferences * Help shape new research directions at the intersection of cancer genomics and therapy resistance Who you are: * Deeply motivated to understand how cancer cells evolve, both intrinsically and under therapeutic pressure * Passionate about applying computational approaches to answer fundamental biological and clinically relevant questions * Actively follows and critically engages with both classic and recent studies in the scientific literature. * Experienced in working with large-scale sequencing datasets and developing reproducible, well-documented analytical workflows * Detail-oriented, able to identify systemic biases in data and quickly identify their source * Collaborative, with the ability to communicate effectively across computational, experimental, and clinical disciplines Who we are: * The Lee Lab is a newly established computational research group within MSK Computational Oncology focused on the mutational mechanisms and rearrangement processes that drive cancer genome evolution. We seek to uncover how and why cancer genomes acquire their complex architectures and how they continue to evolve in patients undergoing treatment. Ultimately, our goal is to identify strategies to intercept this maladaptive evolution and restore physiology. Our most recent story here: ___ * Our work leverages cutting-edge sequencing technologies, including single-cell whole-genome sequencing, long-read sequencing, and multi-omic approaches. Beyond applying state-of-the-art methods, we actively adapt and extend them to address fundamental questions in cancer biology. Many of our projects are in collaboration with experimental investigators. * We are committed to building a collaborative, supportive, and intellectually vibrant lab environment. Requirements: * One of the following academic qualifications: * PhD in Computational Biology, Bioinformatics, Genomics, Computer Science, or a related field * MD with substantial research training in quantitative biology and a strong publication record * Strong programming skills in Python and/or R * Experience in high-throughput sequencing data analysis * Familiarity with Unix/Linux environments and version control * Prior experience with single-cell genomics and/or cancer genomics is highly desirable How to Apply: Please email ___ and add [POSTDOC] in the subject line. Please include the following information in your email as your letter of interest: * A link to 1-2 papers that exemplify your contribution to science, along with a brief description of your specific contribution to each. * Examples of your code on Github that allow us to evaluate your computational skills * Your CV as an attachment Pay Range: $72,000 - $96,405 Pay Range: $0.00 - $10,000,000.00 FSLA Status: Exempt Closing: At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills. MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

Ideal Qualifications:** - PhD or Master's degree in bioinformatics, computational biology, genomics, or a closely related field.

Provides the scientific knowledge layer — understands what is biologically feasible, relevant pathogen biology, and laboratory protocols.Requirements** - PhD in biology, microbiology, virology, immunology, or closely related field - U.Five Eyes country Preferred qualifications - Familiarity wi

The Department of Biomedical Engineering - Prof. Elham Azizi's Lab, is looking for a Staff Associate III to: Functional Knowledge (35%) - Develop advanced probabilistic and causal generative frameworks linking molecular to clinical data; design interpretable representation spaces for tumor-immune dynamics and therapy response. Technical Expertise (25%) - Engineer LLM and diffusion/flow-matching pipelines; integrate multi-GPU distributed training, experiment tracking, and MLOps automation. Problem-Solving Skills (15%) - Innovate adaptive fine-tuning, multi-task learning, and agentic reasoning strategies to improve generalization and data efficiency. Decision Making/Autonomy (10%) - Lead architectural and data design decisions; prioritize experiments aligned with program milestones; evaluate trade-offs between model accuracy and interpretability. Communication Skills (10%) - Present findings at internal symposia and external conferences; co-author manuscripts; write high-quality documentation and technical reports. Mentorship/Leadership (5%) - Mentor junior engineers and research assistants; provide guidance on causal inference methods and AI-in-loop experimentation. B.S./B.E. (minimum) in Computer Science, Biomedical/Electrical Engineering, Statistics, Bioinformatics, Applied Math, or related field. MS or PhD degree is preferred but not required. Required qualifications • Substantial expertise in training deep learning models and tuning large foundation models., • Expertise with developing efficient data loaders for large datasets and optimizing training workflows., • Deep knowledge of probabilistic modelling, self-supervised learning and representation learning, diffusion/VAE/flow matching architectures, • Strong Python, PyTorch/JAX, containerization & MLOps skills; familiarity with distributed training and modern experiment-tracking stacks, • Experience with AI coding tools (e.g., Copilot, Cursor) Preferred extras • M.S. or graduate-level degree in relevant field, • Experience with single-cell and spatial genomic or imaging data, and multimodal integration, • Expertise in statistical causal discovery and inference, • Publications or open-source contributions in generative models, • Strong interest in applications and driving impact in cancer biology and immunology 6+ years of experience in software engineering including: 3+ yrs hands-on experience training generative AI or large-language models at scale 2+ years experience with statistical or generative modeling Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

Associate Research Scientist - Digestive and Liver Diseases The Division of Digestive and Liver Diseases in the Department of Medicine at Columbia University Irving Medical Center invites applications for a research position available to begin at the rank of Associate Research Scientist. Positions include both laboratory and translational research. Work with a multidisciplinary team of scientists and physicians at all levels of training, who are devoted to the study of diseases of the alimentary tract. Many of our laboratories focus on the molecular mechanisms of carcinogenesis, and disease pathogenesis in gastrointestinal and hepatobiliary organs, utilizing advanced mouse models, stem cell research and some translational research involving human cell lines and 3D organoids. Projects include studies of the microbiome, neural signaling, tumor immunity and autoimmunity, Barrett's esophagus, chronic liver injury, inflammation and fibrosis leading to cancer, intestinal stem cell biology and tissue regeneration. As an Associate Research Scientist, this appointment will be covered by a collective bargaining agreement between the University and Columbia Postdoctoral Workers-UAW Local 4100. Minimum Qualifications: MD, PhD, or both. Candidate must have background in research specialty in the Department of Medicine. Preferred Qualifications: Relevant experience in research unit and the ability to supervise graduate students and postdoctoral fellows. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Vagelos College of Physicians and Surgeons (VP&S) at Columbia University Irving Medical Center seeks to fill a position for the Chair of the Department of Systems of Biology. Applicants should be eligible for award of tenure at Columbia University and will be nominated for an endowed professorship. We welcome applications from outstanding scientists with an international reputation in the fields of or related to systems biology and other related areas. VP&S has a storied history of basic science, translational medicine, clinical care, education/training and outreach for more than 250 years. It is part of a stellar university and comprises 30 basic and clinical departments, and more than 20 cross-disciplinary centers and institutes. The Department of Systems of Biology is nationally and internationally renowned with distinguished scientists and a tradition of key discoveries. The Department is committed to the tenets of discovery science and applications to other disciplines, training and education of graduate students and postdoctoral fellows, and nurturing of junior faculty as the next generation of scientific leaders. The candidate will be expected to develop innovative research programs for the Department of Systems of Biology. The candidate will also be expected to conduct vibrant, externally funded research, as well as participate in graduate and medical student teaching. The candidate is expected to provide strategic vision and direction for advancing the understanding of complex biological systems through interdisciplinary approaches and leverage interactions with the nine basic science departments at VP&S, the NYP Hospital, the New York Genome Center, the Chan Zuckerberg Biohub New York, and other scientific institutes, to develop and run a robust systems biology program. Responsibilities: • Leadership: Provide visionary leadership for the Department of Systems Biology, guiding its strategic development and fostering a culture of excellence in research, teaching, and service., • Research: Lead a dynamic research program focused on elucidating the principles underlying complex biological systems, integrating computational modeling, experimental biology, and data science approaches., • Collaboration: Facilitate interdisciplinary collaborations both within the department and across other departments, centers and initiatives, fostering a culture of collaboration and innovation., • Teaching and Mentorship: Contribute to graduate education through the development and delivery of courses in Systems Biology, as well as mentorship of students at all levels., • Grant Acquisition: Secure external funding to support research activities, including grant writing and sponsorship of research proposals., • Professional Service: Engage actively in professional societies, scientific committees, and outreach activities to promote Systems Biology research and education., • Promote career advancement and international visibility of junior and mid-career faculty in and outside the department., • Actively participate in providing long-term strategic vision for Columbia University Irving Medical Center to advance basic and translational research in coordination with other departments, centers and programs., • Applicants should have a PhD, MD, MD/PhD or equivalent degree, substantial national and international stature, and expertise in managing large-scale research programs. The candidate is expected to provide leadership for the Department of Systems of Biology, and articulate a vision for its continued growth, supported with a firm commitment to the recruitment of multiple new faculty members and facilities to match the recruitments., • Distinguished record of scholarly achievements, including a significant publication record in leading scientific journals and a demonstrated ability to secure external research funding., • Demonstrated international leadership in the field of systems biology, through organization of conferences and serving on funding and award committees., • Leadership experience in academic or research settings, with a proven track record of fostering collaboration and promoting excellence., • Strong commitment to graduate and/or medical education, including a record of effective teaching and mentorship. Experience in mentorship of junior scientists and mid-career scientists will be considered as a plus. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Oppurtunity This opportunity to join the Department of Pediatrics at the Vagelos College of Physicians and Surgeons at the rank of Postdoctoral Research Scientist is an exciting one. Columbia University Irving Medical Center, one of the nation's foremost academic health science centers. The Department of Pediatrics at Columbia University Irving Medical Center is the top in comparison with other pediatrics department in the NY region in NIH research funding. The primary responsibility of this role is the characterization and validation of chemical compounds identified from throughput screens ongoing for a group of genetic disorders known as lysosomal storage diseases affecting the central nervous system (e.g. metachromatic leukodystrophy and Krabbe disease). The Postdoctoral Research Scientist will work on examining analogs synthesized from "hits" from two innovative cell-based and biochemical assays, using imaging and tandem mass spectrometry approaches. The successful candidate will have completed a PhD and/or MD and have experience in the following areas: Key Responsibilities • Basic molecular biology techniques include but are not limited to, molecular cloning, transfection, infection, RNA isolation, and Northern blotting., • Perform and develop lipids and sphingolipids extraction methods from diverse matrices, with the goal of identifying novel surrogate disease markers through tandem mass spectrometry., • Perform animal (mouse) experimentation, including general husbandry care, organization of murine colonies, breeding, neurobehavioral assessments with specific instrumentation, surgeries, periodic small molecule administration at different routes, general health assessments, postmortem perfusion, organ/tissue dissection, and other animal procedures., • Perform tissue cryosection and immunofluorescence staining procedures for confocal microscopy and MALDI-TOF and electron microscopy studies., • Familiar with concepts of parametric and non-parametric statistics, GraphPad, Excel, PubChem, PDB, ImageJ, AxoSeg, Volocity, and ZEN 2009 edition., • Present and write peer-review articles and progress reports and prepare presentations as oral or poster in scientific meetings. Columbia University is an Equal Opportunity/Affirmative Action Employer and Educator. The University is dedicated to the goal of building a culturally diverse and pluralistic faculty and staff committed to teaching and working in a diverse environment, and strongly encourages applications from women, minorities, individuals with disabilities, and veterans. Columbia University welcomes applications from individuals who may have had nontraditional career paths, or who may have taken time off for family reasons (e.g. children, caring for disabled or elderly family), or who have achieved excellence in careers outside of academia (e.g., in professional or industry service). The University is responsive to the needs of dual career couples and is committed to supporting the work-life balance of its faculty. We are interested in candidates who have a record of success advising and mentoring individuals from groups underrepresented in higher education and is particularly interested in candidates who have research interests in subjects that will contribute to the understanding of diversity and equal opportunity. • Must have a doctorate degree (M.D. or Ph.D.), • Consistently strong interpersonal skills and the ability to build and sustain effective working relationships with professionals in other disciplines., • The ability to create a high-energy results-oriented work environment that encourages colleagues and staff to value each other's contributions. Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

Research Intern (PhD), Machine Learning. You will contribute to the development of novel machine learning approaches for biological data analysis and interpretation. You are currently pursuing a PhD in Machine Learning, Computer Science, Computational Biology, or a related field.

Associate Research Scientist position available immediately in a leading laboratory investigating host-pathogen interactions.Self-motivated individuals with PhD degree or equivalent with a strong background in one or more areas of immunology, microbiology, cell and molecular biology, and cancer biol

The Experience You’ll Need PhD in a relevant field (computational biology, bioinformatics, neuroscience, cell biology, etc. The Impact You’ll Make As the leader of Recursion’s neuroscience computational biology team, you will be at the forefront of reimagining neuroscience drug discovery usin

A leading research accelerator for AI is seeking remote experts with a PhD in Biology or related fields to fine-tune AI models. Candidates need strong biology skills and clear communication abilities, but no prior AI experience is required.

Remote contract for PhDs in Biology, Biotechnology, Biochemistry, or related fields. Work on cutting‑edge projects with top AI labs while earning up to $50+/hour, fully remote, with flexible weekly hours. You’ll design problems, check how well AI solves them, and work with researchers to build b

The Experience You’ll Need PhD in a relevant field (computational biology, bioinformatics, neuroscience, cell biology, etc. The Impact You’ll Make As the leader of Recursion’s neuroscience computational biology team, you will be at the forefront of reimagining neuroscience drug discovery using

The Experience You’ll Need PhD in a relevant field (computational biology, systems biology, bioinformatics, neuroscience, etc. OR MS in a relevant field Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate m

Collaborate with researchers to refine benchmarks across undergraduate to PhD-level biology topics. Requirements PhD (pursuing or completed) in Biology, Biotechnology, Biochemistry, or a related field. Strong biology reasoning and problem-solving skills across advanced domains.

Job Description Join our team and help build the world's first biological reasoning model. Work with us to build generative foundational models that decode biological systems across scales — from molecules to organisms — enabling us to predict, understand, and program living systems in ways never before possible. Output Biosciences is currently in stealth, operated by a team of repeat founders and biotech veterans with multiple exits in AI and biology, and backed by top VCs including Y Combinator. As a Generative AI Research Scientist, you'll work alongside our founders and team members to develop advanced generative models that can synthesize and design biological systems at multiple scales. Building upon our biological reasoning model, you'll focus on creating the generative capabilities that turn insights into innovations. * ⁠You will design and develop cutting-edge generative models specifically for biological data, creating AI systems that can generate novel molecular structures, protein designs, cellular components, and biological pathways. * You will design and implement state-of-the-art generative algorithms including diffusion models, language diffusion models, diffusion transformers, and flow matching approaches and tailor them to biological constraints and properties * You will train and scale innovative AI models using large, diverse biological multi-modal datasets across distributed GPU clusters. * You will solve challenging AI research problems at scale, tackling key aspects such as model architecture and scaling, pre-training and fine-tuning strategies, and rigorous evaluation methods. * Your work will span various advanced generative AI architectures, including transformers, diffusion models, and autoencoders, exploring and implementing these techniques to push the boundaries of biological AI. Who We're Looking For: * You have a Bachelor's degree in Computer Science, Computer Engineering, Mathematics, Physics, or a relevant technical field. * You have a PhD with 2 years of research experience, or a Bachelor's degree with 4+ years of research or industry experience in Deep Learning, Artificial Intelligence, or other relevant fields. * You have a strong publication record in top-tier AI conferences or journals (e.g., NeurIPS, ICML, ICLR). * You have extensive hands-on experience building and training generative models, such as diffusion models, GANs, VAEs, normalizing flows, or autoregressive models. * You are proficient in Python and have expertise in at least one major deep learning framework (PyTorch, TensorFlow, or JAX). Who You Are: * You have excellent problem-solving skills and the ability to quickly adapt to new challenges. * You exhibit a proactive approach to problem-solving, thinking beyond the specific task, taking ownership of challenges, and taking pride in solving them. * You have a mature mindset in ambiguous situations, helping to frame questions and seek clarity while making decisions in the face of uncertainty. * You have excellent communication skills and can clearly articulate complex technical concepts. * You are motivated by making a real impact and are committed to tackling problems of significant consequence with determination and creativity. Bonus points: * You have experience applying machine learning to biological or chemical problems. * You have knowledge of physics, molecular biology, chemistry, computational biology, bioinformatics, cheminformatics or related fields. * You have experience with multi-modal learning. * You have contributed to open-source machine learning projects. * You have experience in developing efficient code in C/C++. Our Values ❤️ Heart: We foster a culture of ownership. We are assembling a team of individuals who are passionate and take pride in their contributions. 🏆 Excellence: We have an unwavering commitment to excellence and continuously challenge ourselves to reach the highest standards. 🚀 Practicality: We value practicality and results-oriented thinking. We are committed to making a tangible impact on the lives of patients and the broader community. 📣 Honesty: We place a high value on honesty and directness. We firmly believe in addressing issues as they arise, in an open and transparent manner. 🎮 Fun: We believe that life is too short to not have fun. Our goal is to create a workplace that is fun, engaging, rewarding and fulfilling. What We Offer * We encourage new and different ideas, creativity and contrarian thinking * Healthy feedback focused environment to help you strive - leadership will have high expectations, regularly share constructive feedback, support you and help you grow, and welcome receiving feedback and ideas from you * You own your day-to-day management. What we care about is that we all hit our milestones * Competitive salary and equity in a growing, well-funded startup * Excellent medical, dental, and vision coverage Compensation Range: $120K - $250K

Job Description About the job Mercor connects elite creative and technical talent with leading AI research labs. Headquartered in San Francisco, our investors include Benchmark, General Catalyst, Peter Thiel, Adam D'Angelo, Larry Summers, and Jack Dorsey. Position: Mathematics, Biology, Chemistry, and Physics Professional Type: Freelance Compensation: $70–$90/hour Duration: 1–2 months Commitment: 15–25 hours/week, with flexibility up to 80 hours/week Role Responsibilities • Identify and analyze high-impact research papers in Physics, Chemistry, Math, or Science for novel, code-implementable methods., • Break down high-level scientific problems into logical, independently testable subproblems., • Develop "Gold Standard" Python solutions for subproblems and create corresponding unit tests., • Review peer prompts, golden solutions, and unit tests for accuracy and comprehensiveness., • Collaborate with AI research teams to improve model outputs and elevate training data quality. Must-Have • Bachelor's, Master's, or PhD in Physics, Chemistry, Mathematics, Biochemistry, or related Computational Sciences., • Strong experience in Python and scientific computing libraries (e.g., NumPy, SciPy, Matplotlib, JAX)., • Ability to translate academic research into structured problem statements., • Proficiency with Git and branch management., • Upload resume, • AI interview: 3 short, 15-minute conversational sessions

Job Description The Role Join our team and help build the world's first biological reasoning model. Work with us to build generative foundational models that decode biological systems across scales - from molecules to organisms - enabling us to predict, understand, and program living systems in ways never before possible. Output is currently in stealth, operated by a team of repeat founders and biotech veterans with multiple exits in AI x Bio, and backed by top-tier VCs including Y Combinator. As a Senior Computational Biologist, you'll work alongside members of our research team and our founders to develop AI systems capable of complex biological reasoning across multiple scales. * You will develop machine learning methods to extend our predictive and generative platform * You will design and execute computational pipelines to validate and prioritized de novo generated molecules using state of the art tools * You will use your deep understanding of biology to design novel therapeutics for hard-to-target proteins with our generative models * You will analyze and integrate large-scale biological datasets * Your work will directly impact the development of our biologically-aware AI platform, transforming the landscape of medicine Make a real tangible impact on millions of lives by pushing the boundaries of AI in biology. Who We're Looking For * You have a PhD in a biological field and strong programming skills in Python * You have experience with computational biology tools such as structure prediction, molecular docking and virtual screening * You have experience working with Protein or Chemical Language Models * You like to work collaboratively in a fast-paced startup environment * You are passionate about using data science to unlock the secrets of biology * You exhibit a proactive approach to problem-solving, thinking beyond the specific task, taking ownership of challenges, and pride in solving them * You have a mature mindset in ambiguous situations, helping to frame questions and seek clarity while making decisions in the face of uncertainty * You have excellent communication skills and can clearly articulate complex technical concepts Bonus Points * You have hands-on experience building AI/ML using PyTorch and Lightning * You have experience with cloud computing platforms like AWS * You have hands-on biology laboratory experience * You have contributed to peer-reviewed publications in computational biology * You have knowledge of machine learning techniques applied to biological data Our Values ❤️ Heart: We foster a culture of ownership. We are assembling a team of individuals who are passionate and take pride in their contributions. 🏆 Excellence: We have an unwavering commitment to excellence and continuously challenge ourselves to reach the highest standards. 🚀 Practicality: We value practicality and results-oriented thinking. We are committed to making a tangible impact on the lives of patients and the broader community. 📣 Honesty: We place a high value on honesty and directness. We firmly believe in addressing issues as they arise, in an open and transparent manner. 🎮 Fun: We believe that life is too short to not have fun. Our goal is to create a workplace that is fun, engaging, rewarding and fulfilling. What We Offer * We encourage new and different ideas, creativity and contrarian thinking * Healthy feedback focused environment to help you strive - leadership will have high expectations, regularly share constructive feedback, support you and help you grow, and welcome receiving feedback and ideas from you * You own your day-to-day management. What we care about is that we all hit our milestones * Competitive salary and equity in a growing, well-funded startup * Excellent medical, dental, and vision coverage Compensation Range: $150K - $250K

Job Description About the job Mercor connects elite creative and technical talent with leading AI research labs. Headquartered in San Francisco, our investors include Benchmark, General Catalyst, Peter Thiel, Adam D'Angelo, Larry Summers, and Jack Dorsey. Position: Mathematics, Biology, Chemistry, and Physics Professional Type: Freelance Compensation: $70–$90/hour Duration: 1–2 months Commitment: 15–25 hours/week, with flexibility up to 80 hours/week Role Responsibilities • Identify and analyze high-impact research papers in Physics, Chemistry, Math, or Science for novel, code-implementable methods., • Break down high-level scientific problems into logical, independently testable subproblems., • Develop "Gold Standard" Python solutions for subproblems and create corresponding unit tests., • Review peer prompts, golden solutions, and unit tests for accuracy and comprehensiveness., • Collaborate with AI research teams to improve model outputs and elevate training data quality. Must-Have • Bachelor's, Master's, or PhD in Physics, Chemistry, Mathematics, Biochemistry, or related Computational Sciences., • Strong experience in Python and scientific computing libraries (e.g., NumPy, SciPy, Matplotlib, JAX)., • Ability to translate academic research into structured problem statements., • Proficiency with Git and branch management., • Upload resume, • AI interview: 3 short, 15-minute conversational sessions

Job Description About the job Mercor connects elite creative and technical talent with leading AI research labs. Headquartered in San Francisco, our investors include Benchmark, General Catalyst, Peter Thiel, Adam D'Angelo, Larry Summers, and Jack Dorsey. Position: [Role Title] Type: [Contract Type] Compensation: $105/hour Location: [Location] Duration: [Duration if present] Commitment: [Hours/Week if present] Role Responsibilities • Evaluate the accuracy and depth of AI-generated content in Biology to strengthen reasoning and rigor in model outputs., • Review complex biological content for alignment with domain principles and methodologies., • Provide clear, structured feedback to AI research teams to improve training data quality and downstream performance., • Develop evaluation rubrics and benchmarks for assessing AI-generated biological tasks and solutions., • Collaborate with subject matter experts to ensure consistency, relevance, and coverage across datasets. Must-Have • PhD in Biology, Microbiology, Virology, Immunology, or closely related field., • Familiarity with molecular biology techniques (cloning, PCR, cell culture)., • Publication record in relevant subdomains., • Upload resume, • AI interview based on your resume

Job Description Join our team and help build the world's first biological reasoning model. Work with us to build generative foundational models that decode biological systems across scales — from molecules to organisms — enabling us to predict, understand, and program living systems in ways never before possible. Output Biosciences is currently in stealth, operated by a team of repeat founders and biotech veterans with multiple exits in AI and biology, and backed by top VCs including Y Combinator. As a Machine Learning Research Scientist, Interpretability, you'll work alongside our founders and team members to develop AI systems capable of processing and reasoning across multiple biological data modalities simultaneously. * You will develop specialized methods for understanding our biological reasoning models, reverse-engineering how they represent and process complex biological information. * You will design and conduct experiments to uncover interpretable features across biological scales. * You will address unique challenges in biological model interpretation, such as disentangling the multi-scale, hierarchical representations of biological systems * You will build biology-specific visualization tools that can map model activations to meaningful biological concepts. Who We're Looking For: * You have a Bachelor's degree in Computer Science, Computer Engineering, Mathematics, Physics, or a relevant technical field. * You have a PhD with 2 years of research experience, or a Bachelor's degree with 4+ years of research or industry experience in Deep Learning, Artificial Intelligence, or other relevant fields. * You have a strong publication record in top-tier AI conferences or journals (e.g., NeurIPS, ICML, ICLR). * You are proficient in Python and have expertise in at least one major deep learning framework (PyTorch, TensorFlow, or JAX). Who You Are: * You have excellent problem-solving skills and the ability to quickly adapt to new challenges. * You exhibit a proactive approach to problem-solving, thinking beyond the specific task, taking ownership of challenges, and taking pride in solving them. * You have a mature mindset in ambiguous situations, helping to frame questions and seek clarity while making decisions in the face of uncertainty. * You have excellent communication skills and can clearly articulate complex technical concepts. * You are motivated by making a real impact and are committed to tackling problems of significant consequence with determination and creativity. Bonus points: * You have experience applying machine learning to biological or chemical problems. * You have knowledge of physics, molecular biology, chemistry, computational biology, bioinformatics, cheminformatics, or related fields. * You have experience with multi-modal learning. * You have contributed to open-source machine learning projects/ * You have experience in developing efficient code in C/C++. Our Values ❤️ Heart: We foster a culture of ownership. We are assembling a team of individuals who are passionate and take pride in their contributions. 🏆 Excellence: We have an unwavering commitment to excellence and continuously challenge ourselves to reach the highest standards. 🚀 Practicality: We value practicality and results-oriented thinking. We are committed to making a tangible impact on the lives of patients and the broader community. 📣 Honesty: We place a high value on honesty and directness. We firmly believe in addressing issues as they arise, in an open and transparent manner. 🎮 Fun: We believe that life is too short to not have fun. Our goal is to create a workplace that is fun, engaging, rewarding and fulfilling. What We Offer * We encourage new and different ideas, creativity and contrarian thinking * Healthy feedback focused environment to help you strive - leadership will have high expectations, regularly share constructive feedback, support you and help you grow, and welcome receiving feedback and ideas from you * You own your day-to-day management. What we care about is that we all hit our milestones * Competitive salary and equity in a growing, well-funded startup * Excellent medical, dental, and vision coverage Compensation Range: $120K - $250K

Job DescriptionResearch Intern (PhD), Machine Learning Join our team and help build the world's first biological reasoning model. Work with us to build generative foundational models that decode biological systems across scales — from molecules to organisms — enabling us to predict, understand, and program living systems in ways never before possible. Output Biosciences is currently in stealth, operated by a team of repeat founders and biotech veterans with multiple exits in AI and biology, and backed by top VCs including Y Combinator. Our internships offer flexible commitment, with a minimum of 20 hours per week, ranging 12 to 24 weeks. We have various start dates available to accommodate your academic schedule. There may be opportunities for full-time employment upon successful completion of your PhD. * You will contribute to the development of novel machine learning approaches for biological data analysis and interpretation * You will design and implement experiments to evaluate and improve AI models using large-scale biological datasets * You will collaborate with our interdisciplinary team to tackle complex challenges in molecular biology and drug discovery * You will present your research findings and contribute to publications in top-tier conferences and journals * You will have the opportunity to work on projects that directly impact the future of medicine and biotechnology Who We're Looking For * You are currently pursuing a PhD in Machine Learning, Computer Science, Computational Biology, or a related field * You have a strong background in deep learning, with experience in frameworks such as PyTorch or TensorFlow * You have a proven track record of research, demonstrated by publications at conferences such as NeurIPS, ICML, ICLR, or relevant computational biology venues * You are proficient in Python and have experience with large-scale data processing and analysis * You have excellent problem-solving skills and the ability to work independently on complex research problems * You are passionate about applying AI to solve real-world challenges in biology and medicine * You have strong communication skills and can effectively present technical concepts to diverse audiences * You thrive in a fast-paced, startup environment and are excited about making a significant impact in a growing field Bonus Points * Experience with biological data analysis or computational biology projects * Familiarity with generative AI models, such as transformers or diffusion models * Contributions to open-source machine learning or bioinformatics projects Our Values ❤️ Heart: We foster a culture of ownership. We are assembling a team of individuals who are passionate and take pride in their contributions. 🏆 Excellence: We have an unwavering commitment to excellence and continuously challenge ourselves to reach the highest standards. 🚀 Practicality: We value practicality and results-oriented thinking. We are committed to making a tangible impact on the lives of patients and the broader community. 📣 Honesty: We place a high value on honesty and directness. We firmly believe in addressing issues as they arise, in an open and transparent manner. 🎮 Fun: We believe that life is too short to not have fun. Our goal is to create a workplace that is fun, engaging, rewarding and fulfilling. What We Offer * We encourage new and different ideas, creativity and contrarian thinking * Healthy feedback focused environment to help you strive - leadership will have high expectations, regularly share constructive feedback, support you and help you grow, and welcome receiving feedback and ideas from you * You own your day-to-day management. What we care about is that we all hit our milestones * Competitive salary and equity in a growing, well-funded startup * Excellent medical, dental, and vision coverage

Job Description About the job Mercor connects elite creative and technical talent with leading AI research labs. Headquartered in San Francisco, our investors include Benchmark, General Catalyst, Peter Thiel, Adam D'Angelo, Larry Summers, and Jack Dorsey. Position: Bioinformatician Type: Contract Compensation: $60–$85/hour Duration: 4 weeks Commitment: Remote Role Responsibilities • Solve complex bioinformatics problems in transcriptomics, genomics, and virology., • Analyze large biological datasets and submit analytical workflows as Jupyter notebooks., • Work independently under a blind protocol with no prior context., • Inform the evaluation of frontier AI models on scientific reasoning., • Utilize Python and/or R for bioinformatics pipelines. Must-Have • PhD or Master's degree in bioinformatics, computational biology, genomics, or related field., • Experience with at least 2 of: RNA-seq analysis, variant calling, metagenomic classification, epigenomic profiling, single-cell analysis, or population genetics., • Proficiency in Python and/or R., • Familiarity with command-line tools (e.g., samtools)., • Upload resume, • AI interview based on your resume