Project Manager
3 days ago
City of London
Project Manager \n Clinical-Stage Gene Therapy \n \n\n • Permanent position within a fast growing Biotech\n, • Hybrid working in London (2 days per week on site)\n, • £70,000-£80,000 per annum\n, • Company bonus and benefits in line with new funding round\n\n \n As Project Manager, you will play a key role in driving the delivery of the company’s clinical-stage gene therapy programme. You will oversee the integrated project plan and coordinate activity across clinical development, regulatory, CMC/manufacturing, quality, finance, commercial planning, and broader company operations. \n \n Working closely with leadership, internal experts, external partners, advisers, and vendors, you will turn strategic priorities into clear plans and deliverables. \n \n Key Responsibilities \n\n • Lead the integrated programme plan, including milestones, timelines, dependencies, owners, risks, and critical activities.\n, • Establish and maintain an effective cross-functional planning and review cadence.\n, • Coordinate clinical development activities, including CROs, sites, data, vendors, regulatory requirements, and Phase 3 preparation.\n, • Bring together CMC, manufacturing, testing, release, technology transfer, stability, and clinical supply activities.\n, • Monitor budgets, forecasts, purchase orders, invoices, and programme-related changes.\n, • Coordinate external partners and vendors, supporting selection, onboarding, delivery, and performance management.\n, • Prepare clear dashboards, programme updates, governance materials, and leadership/board reporting.\n, • Develop practical project-management processes, tools, reporting structures, and documentation as the company grows.\n, • Support financing, partnering, diligence, and other company-building activities.\n, • Proactively identify gaps, challenge assumptions, clarify accountability, and drive actions through to completion.\n\n \n Required Experience & Skills \n\n • Experienced project or programme management within biotech or pharma\n, • Phase 2/3 or global clinical trial experience.\n, • Experience supporting a clinical-stage programme or complex cross-functional development project.\n, • Broad understanding of clinical operations, regulatory, CMC/manufacturing, quality, safety, data, and financial processes.\n, • Experience working with CROs, CDMOs, laboratories, consultants, and other external partners.\n, • Strong skills in programme planning, budgeting, forecasting, governance, risk management, and reporting.\n, • Excellent communication skills and the ability to work confidently with senior leaders and external stakeholders.\n, • Highly organised, proactive, pragmatic, and comfortable working in a fast-moving environment with ambiguity.\n\n \n Additional Desirable expertise: \n\n • Gene therapy, AAV, ATMP, or complex biologics experience.\n, • Experience in Parkinson’s disease, CNS, neurosurgical delivery, or movement disorders.\n\n