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Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law. To characterise the companies biotherapeutic recombinant T-cell receptor based and related molecules using a wide variety of protein characterisation and mass spectrometry methods. To contribute to the development of characterisation methods for the company's biopharmaceutical products, including peptide mapping (LC-MS/MS) and intact mass spectrometry analysis. KEY RESPONSIBILITIES • Supporting drug substance and drug product impurity characterisation and identification, • Performing protein sequence and post translational modification identification, including glycosylation analysis., • Supporting drug substance and drug product process development by performing characterisation of process intermediates, • Contribute to the Development of characterisation methods of ImmTAX and other products, including peptide mapping (LC-MS/MS) and intact mass analysis, • Designing and carrying out biochemical characterisation, chemical stability and comparability studies of biologics/drug products., • Contribute to writing study protocols and reports., • Independently testing and, increasingly, leading lines of investigation. Proposing new experiments based on emerging data and other related information. Providing support on technical aspects to others., • Priorities: establishing priorities for own work and team-based projects; making decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance., • Technical Knowledge: sharing knowledge with the wider team and, across departments representing the department. May also act as a mentor to other colleagues, sharing scientific knowledge. Providing analysis of new techniques and theories from outside the Company to advance the way the company works; sharing these with leaders across the department., • Laboratory records: ensuring that all records and information are up to date, on time and recorded to the correct standard. Supporting and encouraging others to achieve this., • Laboratory equipment: providing technical guidance to others within the team on how to use equipment most effectively., • Reporting: communicating and presenting research findings at meetings with colleagues, senior management and partners., • Adhere to safe working practices in laboratories according to Immunocore EHS policies. PERSON SPECIFICATION Experience & knowledge Essential • Experience in development of HPLC based peptide mapping methods and mass spectrometric characterisation of recombinant proteins or antibodies., • Experience of glycosylation analysis of recombinant proteins or antibodies., • Independently coordinated extensive testing of protein biomolecules., • Experienced in the characterisation of proteins expressed in both microbial and mammalian systems., • Understanding of expected post-translational modifications in biological systems., • Worked in a bench-based biopharmaceutical laboratory environment., • Experienced in assay development, • Familiar with biopharmaceutical stability study principles and interpretation thereof, • Worked and contributed actively in a diverse team environment, • Proposed and driven changes in working practices that have improved efficiency, supported teams through adoption and change, • Presented detailed scientific findings and papers to internal and external audiences Desirable • Experience of glycosylation analysis of recombinant proteins or antibodies, • Experience with late stage/commercial biopharmaceutical assay development and characterisation, • Familiar with the principles of Good Manufacturing Practise (GMP), • Presented at external conferences, • Led a small project team, formally or informally, through a change in practice including project management, • Understanding of analytical requirements to support materials for use in clinical trials Education & qualifications • Essential: BSc. Or MSc. in biochemistry, biotechnology or related discipline, • Desirable: PhD in related discipline

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law. The primary purpose of this role is to contribute to cross functional efforts focused on applying the ImmTAX® platform or other modalities to the development of novel treatments for chronic infections, including HIV and HBV and EBV-associated diseases. The team is involved in multiple stages of the drug discovery and development process, from target discovery all the way to clinical trials. Examples of key preclinical research are published in Yang H et al., Mol Ther. 2016; 24,11; Fergusson J et al., Hepatology 2020; 72,5; Wallace Z et al., Mol Ther 2024; 32, 678. The postholder will plan, design and execute experimental investigations to support the advancement of the Company pipeline, processes and technology capabilities, with guidance from their manager, ensuring that project goals are met within time and budget constraints. They will be expected to demonstrate technical proficiency, rigour in assessing their own data and that of others, scientific creativity and independent thought. This position requires participation and presentation of results at internal meetings, sharing information learned at external scientific meetings and establishing productive relationships with colleagues across Research and other departments. Key Responsibilities: • With instruction and guidance from manager - plan, design, and execute assignments to meet project goals within defined timeframes, • Execute experiments to address key scientific questions and enable project progression, utilizing range of molecular and cellular techniques including some of the following: NextGen sequencing, DD-PCR, qPCR, cell culture, flow cytometry, ELISpots, ELISAs,, • Some work will be conducted in a containment level 3 (CL3 facility) and will require handling of human viruses, • Analyse data, interpret results, and make recommendations, • Proactively expand scientific/technical knowledge in relevant fields including HIV/HBV/EBV related disease biology and drug development through review of scientific literature/ conference updates, peer to peer mentoring, and attendance at seminars/conferences in line with company strategy, • Work effectively in a matrixed team structure and as part of cross functional teams, • Participate and present results at internal meetings, • Establish relationships and possible collaborations within and outside of the company Education, Experience and Knowledge: Essential Qualifications: • PhD in molecular biology, cell biology, genomics, virology, immunology, or related discipline and 0-2 years related experience, • Alternatively, a BSc or MSc with significant work experience in relevant scientific areas Preferred Qualifications: • Knowledge/expertise of Immunology/HIV/HBV/EBV, • Flow cytometry, ELISAs, ELISpots, • Viral integration site analysis

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law. The primary purpose of this role is to serve as a recognized technical leader in formulation development, leveraging extensive experience and expert knowledge to drive innovation and contribute to the company's scientific strategy. The incumbent is expected to advocate for process, platform, and technology improvements, and apply advanced knowledge of scientific principles and the drug development process to solve extremely complex problems. The individual will exercise independent judgment in developing methods and techniques, consistently making the right calls to achieve results. This position will be responsible for conducting and designing experimental investigations to support a low & high dose parenteral bio-pharmaceutical in the development and management of integrated formulation strategies supporting Immunocore's bio-pharmaceutical platforms. The formulation role will be a hands on role, primarily focussed on lab work designing and performing experimental work. It will also cover drug delivery approaches, investigate novel technologies such as LNP, Pegylation and other delivery systems applicable to biologicals. The role will also cover early stressing studies, formulation excipient screening, CMC process support, drug substance and drug product through to compatibility with final patient delivery systems. Support and direct IUS studies and progress the clinical programmes. Support and respond to main stake holders for example Clinical and Regulatory teams in the delivery of the clinical strategies. To work in close collaboration with the Head of Formulation, CMC teams and related functions to input into the formulation related sections for regulatory filings, development reports and other development related documents. Advanced people management skills are essential, including managing changing priorities while maintaining team motivation. They will create a safe environment for learning from mistakes, establish clear career paths, and hold career development conversations. The individual will engage in difficult conversations where appropriate, inspire action, and show employees how they contribute to higher goals. Key Responsibilities: • Conducting experiments, observing, interpreting and responding to results., • Maintaining and increasing technical knowledge in relevant fields through self-study, observation, attending relevant conferences and training courses., • Maintaining accurate records of all work by completing laboratory notebooks on time, following Company procedures, • Ensuring that laboratory equipment is operated in accordance with safety and risk guidelines; acting promptly to report any faults or problems to the relevant member of staff., • Priorities: establishing priorities for own work and team-based projects; making decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance., • Technical Knowledge: sharing knowledge with the wider team and, across departments representing the department both internally and externally. May also act as a mentor or manager to other colleagues, especially new hires, sharing scientific and company knowledge. Increasingly providing analysis of new techniques and theories from outside the Company to advance the way the company works; sharing these with leaders across the Company., • Laboratory records: ensuring that all records and information are up to date, on time and recorded to the correct standard. Supporting and encouraging others to achieve this., • Laboratory equipment: providing technical guidance to others within the team on how to use equipment most effectively; making recommendations regarding acquisition of new pieces of equipment., • Health & Safety: championing and helping others to understand H&S within the company, providing ad-hoc training as required., • Reporting: communicating and presenting research findings at meetings with colleagues, senior management and partners. Experience and Knowledge: Essential • Background in recombinant protein or antibody formulation, Drug delivery of biologics. analytical development or protein characterisation, with proven industry experience and exposure to formulation strategies., • Experience in design of formulation studies, including the utilisation of design of experiments principles., • Strong expertise in electrophoretic or chromatographic assays and general biochemical lab techniques. Desirable • Experience of process development for production of biologics and conjugation of biomolecules, • Experience with lyophilisation development of Biotherapeutics, • Familiar with biopharmaceutical stability study principles, • Familiarity with novel drug delivery formats, • proactive in ensuring high quality of their work and seeking additional responsibilities to help meeting the goals of the team, • Presented detailed scientific findings and papers to internal and external audiences Essential Qualifications: • Essential: PhD In bio-manufacturing, protein engineering, biochemistry, molecular biology or related discipline, • Industrial company experience delivering formulations through drug development phases, • Normally requires a PhD in a scientific discipline and a minimum of 8+ years related experience; may include post-doctoral experience.

About Us: A&B Smart Materials is an Oxford University–based materials science venture founded by Oxbridge graduates. We are pioneering the next generation of bio-based, biodegradable superabsorbent polymers (SAPs) to replace synthetic SAPs. SAPs are “magic-like” materials that absorb hundreds of times their weight in water. They are used primarily in hygiene (diapers, pads, cosmetics) and agriculture (soil enhancers), representing a $17.6B global market. With new EU regulations banning non-biodegradable SAPs in soils from 2028, there is an urgent demand for sustainable alternatives. We are backed by some of the most prestigious investors in the world, and are part of the Creative Destruction Lab — the leading accelerator for deep tech ventures. Our work has also been recognised globally, including being named a “DeepTech Pioneer” at Hello Tomorrow (2025) and Winner of the Cleantech StartUp Award (South East, 2024). Backed by world-class advisors and based at Oxford’s Begbroke Science Park with access to cutting-edge labs, our mission is to make sustainable SAPs the global standard. The Position: We are seeking an experienced Lead Research Scientist with a proven track record in sustainable superabsorbent polymer (SAP) development. This is not an entry-level research role — it is a chance to bring decades of expertise into a startup where your insights can directly shape the technology roadmap and help us accelerate progress while navigating the complexities of sustainable SAP development. You will work in close collaboration with our CTO to help define the company’s technology direction, ensuring alignment between breakthrough science and commercial growth. You will also play a pivotal role in mentoring our research team, developing IP, and translating scientific progress into scalable solutions. Key Responsibilities: • Lead SAP innovation: design and oversee R&D pathways for sustainable superabsorbent polymers., • Bring deep scientific and practical insights into SAP design, performance, and scalability., • Work closely with the CTO to shape technology direction and research strategy., • Plan, execute, and interpret lab experiments with scientific and commercial impact in mind., • Partner with the founding team to develop IP, refine technology pathways, and align R&D with commercial goals., • Mentor junior scientists and instil best practices in experimental design and polymer chemistry., • Represent A&B Smart Materials in publications, patents, and conferences. Qualifications: • PhD in Polymers, Biopolymers, or a closely related field., • 10+ years’ experience in polymers/biopolymers, with a strong preference for hands-on work in sustainable SAP development., • Industrial or postdoctoral track record in bringing polymer innovations from lab to scale., • Strong wet lab expertise, with ability to design and interpret complex experiments., • Proven leadership experience, ideally managing R&D teams or cross-functional research programmes., • A history of innovation — patents, publications, or commercialised technologies in SAPs. Desired Experience (Nice to Have): • Previous experience working at company/startup developing sustainable Super Absorbent Polymers., • Previous experience working at a major chemical manufacturer., • Background at a large hygiene company with exposure to SAP applications., • Experience bridging between corporate R&D and fast-moving startups, bringing structure, rigour, and adaptability., • Strong network within the SAP, polymer chemistry, or hygiene/agriscience communities. Benefits & Perks: • Competitive compensation package of up to £100,000 with generous equity package, so you share directly in the company’s success., • Significant long-term upside as the company scales in a rapidly growing global market., • Comprehensive health insurance and wellbeing package., • Over 28 days paid holiday annually., • Flexible working hours with hybrid (on-site + remote) options., • The chance to shape the global future of sustainable SAPs in a company building momentum with leading investors, accelerators, and awards., • A creative, fast-moving environment where your experience will have a direct impact on products, IP, and company growth. At A&B Smart Materials, we are looking for more than talent — we are looking for deep expertise. If you have spent years pushing the boundaries of sustainable SAPs and want your knowledge to directly influence a breakthrough technology, we want to hear from you. Application Form: Recruitment email:

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Any additional information you require for this job can be found in the below text Make sure to read thoroughly, then apply.OxfordImmunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transf

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Ensure all your application information is up to date and in order before applying for this opportunity.OxfordImmunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines w

We are seeking an experienced Lead Research Scientist with a proven track record in sustainable su.

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