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Downstream Process Development Scientist 12-month maternity cover | Darlington | £32,500 – £40,500 per annum + attractive benefits About the Role: We are seeking a hands-on Downstream Process Development Scientist to join a bioprocessing team in Darlington on a 12-month maternity cover. This is a practical, lab-based role focused on the design, development, and optimisation of downstream purification processes for advanced biologics. You will play a key role in delivering DSP activities across a range of modalities, including viral vectors and nucleic acid-based products, in a fast-moving and highly experimental environment. Reporting into the DSP leadership team, you will be expected to hit the ground running in the lab — running experiments, solving problems, and adapting processes, as projects evolve. This role suits someone who enjoys flexibility and scientific creativity rather than rigid, highly constrained environments. The role is based on-site in Darlington, working as part of an established DSP team of approximately 11 scientists. What You’ll Be Responsible For: Downstream Process Development • Design, develop, and optimise downstream purification processes for biopharmaceutical products, • Carry out hands-on laboratory experimentation and pilot-scale DSP runs, • Apply chromatography and filtration techniques to improve yield, purity, and robustness Chromatography & Filtration • Operate and develop chromatography methods using ÄKTA systems, • Design and optimise chromatographic purification strategies, • Apply tangential flow filtration (TFF) and related DSP technologies Analytical & Data Interpretation • Analyse and interpret experimental data using appropriate techniques, • Maintain high-quality experimental records using ELN and document management systems, • Present experimental conclusions clearly for internal and external stakeholders Collaboration & Laboratory Operations • Work closely with upstream, analytical, and project teams to deliver customer programmes, • Contribute to the efficient operation of the DSP laboratory, including equipment care and maintenance, • Support scale-up, knowledge transfer, and process troubleshooting activities About You: You are a practical downstream processing scientist who enjoys being in the lab and is comfortable working in an evolving, sometimes ambiguous research and development environment. You bring curiosity, adaptability, and a willingness to try different approaches — and you’re not phased by processes that aren’t fully defined from day one. You’ll bring: • Hands-on experience in downstream processing gained in industry or academia, • Strong, practical experience using ÄKTA chromatography systems, • Experience designing and optimising chromatography-based purification processes, • Familiarity with purification techniques including primary separation, clarification and TFF, • Flexibility to adjust working hours around experimental needs Desirable (but not essential): • Experience working with a variety of recombinant proteins, viral vectors, DNA/RNA-based products, • Experience in early-stage, development-focused or non-rigid GMP environments Applicants from academia are welcome, provided you have strong hands-on ÄKTA and purification experience. Why Join? • A genuinely hands-on laboratory role with real scientific ownership, • Exposure to emerging modalities and advanced bioprocessing technologies, • A collaborative team that values experimentation and problem-solving, • Opportunity for the role to convert to permanent, • Competitive salary (£32.5k–£40.5k) Location & Working Pattern • Based on-site in Darlington, • Flexible working hours aligned to experimental requirements

Join Riverdale-Healthcare as an Associate Dentist at Eston Dental Practice, located in Tees Valley. This role offers around 6,000 UDAs at £16 per UDA, a 50% split on private and lab fees, and a chance to work with a dedicated team. You will enjoy a range of perks including a dental academy, mentoring network, and opportunities to gain extra income through mentoring roles. The position is open to fully qualified dentists who are GDC registered and eligible to work in the UK. Riverdale-Healthcare values diversity and focuses on creating a supportive environment for both patients and staff. #J-18808-Ljbffr

Looking for a new challenge with a supportive, forward-thinking team? Join us in Eston and work with a practice that truly invests in you. • Monday - Friday (around 6,000 UDAs available depending on days worked), • £16 per UDA, • 50% private/lab fee split, • Hygiene and Therapists available onsite, • A highly engaged Regional Director and Clinical Lead who will guide you through the transition and champion your ongoing growth, • Established patient list to take on, • Working alongside a Qualified Dental Nurse, • Our very own Dental Academy – with courses, mentoring & big-name connections, • A mentoring network so you’re never on your own, • Chance to step into a mentoring role with extra income, • Proven potential to grow your private list (with in-house marketing magic), • Discounts galore: CPD, High Street, Blue Light, courses & more, • Free mortgage advice, • Charity match funding & a Refer a Friend bonus up to £7,500, • Visa sponsorship available (T&Cs apply), • Special interests are encouraged and enthusiastically supported so your clinic can be designed around you!, • Gain your NHS pension, Enhanced NHS Maternity and Paternity leave, Enhanced NHS Sick pay and build your private list Riverdale Healthcare is an exciting, growing dental group with practices right across England. From NHS to private and specialist care, we’re all about making every patient’s experience positive and stress-free. Our friendly, talented teams are passionate about delivering the kind of dentistry that makes a real difference. At Riverdale, we put people first. We believe in honesty, kindness, and always doing the right thing – for our patients and for each other. We celebrate diversity, welcome new ideas, and love finding better ways to do things. Most importantly, we work together, creating a supportive and inclusive place where both patients and colleagues feel valued. • GDC registration + performer number, • Indemnity cover, • Eligibility to work in the UK #J-18808-Ljbffr

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