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Downstream Process Development Scientist 12-month maternity cover | Darlington | £32,500 – £40,500 per annum + attractive benefits About the Role: We are seeking a hands-on Downstream Process Development Scientist to join a bioprocessing team in Darlington on a 12-month maternity cover. This is a practical, lab-based role focused on the design, development, and optimisation of downstream purification processes for advanced biologics. You will play a key role in delivering DSP activities across a range of modalities, including viral vectors and nucleic acid-based products, in a fast-moving and highly experimental environment. Reporting into the DSP leadership team, you will be expected to hit the ground running in the lab — running experiments, solving problems, and adapting processes, as projects evolve. This role suits someone who enjoys flexibility and scientific creativity rather than rigid, highly constrained environments. The role is based on-site in Darlington, working as part of an established DSP team of approximately 11 scientists. What You’ll Be Responsible For: Downstream Process Development • Design, develop, and optimise downstream purification processes for biopharmaceutical products, • Carry out hands-on laboratory experimentation and pilot-scale DSP runs, • Apply chromatography and filtration techniques to improve yield, purity, and robustness Chromatography & Filtration • Operate and develop chromatography methods using ÄKTA systems, • Design and optimise chromatographic purification strategies, • Apply tangential flow filtration (TFF) and related DSP technologies Analytical & Data Interpretation • Analyse and interpret experimental data using appropriate techniques, • Maintain high-quality experimental records using ELN and document management systems, • Present experimental conclusions clearly for internal and external stakeholders Collaboration & Laboratory Operations • Work closely with upstream, analytical, and project teams to deliver customer programmes, • Contribute to the efficient operation of the DSP laboratory, including equipment care and maintenance, • Support scale-up, knowledge transfer, and process troubleshooting activities About You: You are a practical downstream processing scientist who enjoys being in the lab and is comfortable working in an evolving, sometimes ambiguous research and development environment. You bring curiosity, adaptability, and a willingness to try different approaches — and you’re not phased by processes that aren’t fully defined from day one. You’ll bring: • Hands-on experience in downstream processing gained in industry or academia, • Strong, practical experience using ÄKTA chromatography systems, • Experience designing and optimising chromatography-based purification processes, • Familiarity with purification techniques including primary separation, clarification and TFF, • Flexibility to adjust working hours around experimental needs Desirable (but not essential): • Experience working with a variety of recombinant proteins, viral vectors, DNA/RNA-based products, • Experience in early-stage, development-focused or non-rigid GMP environments Applicants from academia are welcome, provided you have strong hands-on ÄKTA and purification experience. Why Join? • A genuinely hands-on laboratory role with real scientific ownership, • Exposure to emerging modalities and advanced bioprocessing technologies, • A collaborative team that values experimentation and problem-solving, • Opportunity for the role to convert to permanent, • Competitive salary (£32.5k–£40.5k) Location & Working Pattern • Based on-site in Darlington, • Flexible working hours aligned to experimental requirements

We are recruiting for companies who are looking to employ our Network Engineer Traineeship graduates to keep up with their growth. Whether you are working full time, part time or unemployed, this package has the flexibility to be completed at a pace that suits you. The first step is completing a sel

A leading design and manufacturing company is seeking an Embedded Software Engineer to enhance their IoT solutions.This full-time, onsite role requires excellent programming skills in C and C++, alongside strong analytical and problem-solving abilities.You will be responsible for integrating APIs, c

NECSWS in Tees Valley seeks a 1st Line Support role, providing crucial IT service support from our Hartlepool office. Responsibilities include managing customer requests, resolving issues, and maintaining documentation. The ideal candidate has excellent customer service skills and experience in a si

Darlington Borough Council is seeking a Residential Child Care Worker to act as a corporate parent for children looked after by the local authority. Applicants must hold or be willing to pursue a Level 3 Diploma for Residential Child Care. The role includes caring for children with complex needs, su

National Highways currently have an exciting opportunity for a Programme Delivery Manager to join our team based in our Yorkshire, North East region. Recognised qualification in relevant engineering discipline or extensive experience in delivery of civil engineering projects and programmes. Extensiv

Your base location will be any Environment Agency office.

A regional community development organization in Tees Valley is seeking a Community Development Officer to support Refugee-Led Community Organisations throughout the region. Ideal candidates will have a strong background in community engagement and development, with a focus on refugee support. This

The Regional Refugee Forum North East are recruiting for a Community Development Officer to support Refugee‑Led Organisations and Community Mobilisers across the North East Region, to work together to bring change in policy and practice which affects refugees and people seeking sanctuary. Assess t

Baked Product Development Manager. We’re looking for a Baked Product Development Manager to join us at KP Snacks. You’ll ensure product designs are factory‑ready and transitioned smoothly into production using our P2M and MoPD stage gate processes.

A leading debt collection company in Tees Valley is seeking a skilled IT Support Engineer to provide second line technical support. Enjoy benefits like gym contributions, flexible hours, and career development opportunities. The role requires excellent Microsoft 365 skills and ITSM experience.

We’re excited to offer an incredible opportunity for a Development Chef to join our dedicated and professional New Product Development team in Middlesbrough!. Work collaboratively with development technologists and chefs, including travel to other sites as required. Promote a strong health and saf

The Programme Lead, together with a Senior Speech and Language Therapist and seven speech and language support workers, will create the model of early intervention support. The programme funds innovative workforce models to identify and support children with speech and language challenges at an earl

A local government authority in Tees Valley seeks a passionate part-time Early Years Development Adviser to promote inclusive learning for children aged 0-7. You will work with schools to enhance early education outcomes and deliver professional development sessions.

We’re looking for a Learning and Development Specialist (Design & Delivery) to join our expanding team and play a key role in creating and delivering high-quality learning experiences across the Group. You’ll design and deliver training across key areas including contact centre operations, induc

A proactive, “get up and go” attitude and the confidence to think ahead and take initiative. Drive compliance and capability by tracking mandatory training and supporting our competency framework (Comaea). Help power our learning culture by overseeing our LMS (iLearn / Caladas) and maintaining a

The Grants and Programme Officer will play a vital role in ensuring the smooth and efficient delivery of our new small grant funding programme and will also lead researching and developing approaches to support new entrants to the VCSE sector, emerging and current leaders, community leaders and yout

A leading fashion retailer in Tees Valley is seeking an Assistant Store Manager to support daily operations and enhance customer experiences. You will lead a team, manage responsibilities in the Store Manager's absence, and contribute to a dynamic retail environment. Ideal candidates have a passion

A governmental environmental organization in the UK is hiring for a position focused on data quality auditing.

Resolve basic hardware / software problems. We are proud of the benefits we offer employees of NEC Software Solutions. NEC Software Solutions is an equal opportunities employer, welcoming applications from all communities.

Tees Esk and Wear Valleys NHS Foundation Trust is seeking an experienced Programme Manager to lead significant transformation programmes in Durham and Tees Valley. Candidates should have substantial experience in health services management, particularly in managing complex programmes, and strong com

Ensure all digital initiatives adhere to corporate IT standards, Information Security, and a relentless focus on Zero Harm. Lead training initiatives to ensure the project team and supply chain are proficient in the selected digital toolsets. As the Digital Lead, you will own the project's digital r

The Compleat Food Group is seeking a Development Chef to join their New Product Development team in Middlesbrough. The ideal candidate will have experience in a development kitchen or food manufacturing, a professional cookery qualification, and strong communication skills.

As an IT Services Assistant, you will be the first point of contact for all IT-related queries within the firm. We are currently looking to recruit a IT Services Assistant to join our internal IT Team. This is a full-time role which is 35 hours per week, however at EMG Solicitor we work flexibly, it

NEC Software Solutions seeks a First-Line IT Support professional to join their Hartlepool office. Candidates should possess excellent customer service skills, be proficient in Microsoft Office, and have experience in a first-line IT support position. The role involves managing customer mailboxes, l

If you are a CNC Programmer/Engineer seeking a secure role with strong benefits, career progression, and cutting‑edge CNC technology, this is an outstanding next step for an experienced CNC Programmer/Engineer. The successful CNC Programmer/Engineer will manufacture tooling, fixtures, jigs, and be

A game development studio seeks an Associate Generalist Programmer to work remotely within the UK.

The position involves providing first-line IT support, managing customer mailboxes, and ensuring adherence to service level agreements. The role offers benefits such as private medical cover, 25 days paid holiday, and a pension plan. Flexibility in approach and self-motivation are key attributes req

Populus Select Ltd is looking for multiple Software Developers in Tees Valley, England. NET to design and maintain scalable software solutions.

A leading electrical equipment supplier in Tees Valley seeks a recent graduate eager to join their dynamic graduate program. This role focuses on developing sales skills and business operations knowledge, leading to a diverse B2B sales management position.

This is a varied and rewarding second line IT Support Engineer role at the heart of the CDER Group IT function. We celebrate diversity and equal opportunities and are committed to creating an inclusive environment for all employees that represents a variety of backgrounds, perspectives and skills. W

Be among the first 25 applicants.From CNN to The Huffington Post, the world is talking about the innovative movement that is downsizing global poverty.The Borgen Project believes that leaders of the most powerful nations on earth should be doing more to address global poverty.The national campaign i

We aim to hire talents globally with.Are you willing to proactively take part in the.Digitalization of our communities.Our Graduate Program provides an immersive experience in our company from day 1.Milan with trainings and activities led by the Prysmian Academy in collaboration with a Top‑Ranking

You’ll design and deliver training across key areas including contact centre operations, induction and onboarding, management development, and practical and behavioural skills. We understand that everyone is different and, with our unique approach to fairness, we ensure that clients, customers, an

A well-regarded medical practice in Tees Valley is looking for a motivated Salaried GP to join a supportive team.

Responsibilities include delivering play activities and ensuring play areas are safe and child-friendly. Candidates must have experience working with children, understand safeguarding, and be flexible with availability, including evenings and weekends. In this role, you will create a safe and welcom

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Advise C-suite and senior leadership on unlocking value from technology investments, specifically embedding AI and Agentic AI into IT operating models. Proven background in management consulting, with significant experience delivering strategic digital technology advisory engagements. The role focus

This role sits at the heart of delivery—bridging technology and operations to implement a key integration between a.

UK Sales Hunters – This Role is NOT for Everyone.If you can walk into the UK market, open doors, and close IT services deals, keep reading.If not, this might not be for you.Green Start is Hiring: IT Services Sales Manager – UK / Europe.What Makes This Role Exciting?.This is a pure hunting role �

Accountable for end-to-end IT operations, outsourced service providers, and technology risk, with a strong focus on performance, governance, and commercial value.

Collaborate asynchronously with research teams to refine evaluation frameworks for technology-domain AI. IT services firm, systems integrator, or technology consultancy. For details about the interview process and platform information, please check: .

Director of Information Technology. The successful candidate will be responsible for ensuring the firm’s technology infrastructure delivers exceptional service, security, and reliability, while working closely with stakeholders across the business and managing external technology partners. Proven

Burton (Hybrid – 2/3 days on site).Directorship / close alignment with Infrastructure.We’re hiring a Lead EUC Engineer to take ownership of our end‑user computing environment and drive our modern workplace strategy forward.This isn’t a basic “build engineer” role — we’re looking for

Work closely with Information Architect to ensure data curation remains line with Enterprise Data Model Standards.

This is a hands‑on role focused on IT support, user onboarding/offboarding, access management, endpoint support, and office technology.

Local IT service coordination and operational delivery, ensuring that all in–country technology services meet business standards, key performance indicators, and business needs. Liaise with Information governance team (IGRM) and relevant governance bodies to ensure compliance with policies and sta

Ability to synthesize information and maintain clarity under pressure. Bachelor’s degree in business, Information Systems, or equivalent experience.