Computational Biologist - Pharma Delivery
il y a 2 jours
Paris
Computational Biologist - Pharma Delivery Paris, France Position overview Orakl Oncology is pioneering a new paradigm in cancer drug development by building the world’s largest cohort of patient-derived organoid (PDO) avatars. Through our unique platform, we generate extensive multi-modal data from these avatars to discover and validate new oncology therapeutics with real-world patient relevance. We are seeking a Computational Biologist to play a central role in delivering the partnership projects. As part of the Product Team, you will work on a daily basis with the Computational Biology and Data Science teams to deliver in-depth analysis and studies for our partners. You will interpret results in their biological and clinical context and translate them into clear, actionable insights for both internal teams and pharma collaborators. You’ll work in a fast-paced, project-driven environment where timelines are often set by our pharma partners; so comfort with short turnaround cycles and the ability to prioritize effectively are key. What you’ll do • Deliver project analyses - Run established analysis workflows on omics and clinical datasets in line with project timelines and partner milestones. Apply and contribute to analysis plans while ensuring reproducibility, traceability, and adherence to quality standards., • Interpret and contextualize results - Go beyond descriptive outputs: build biological narratives that connect analytical results to known pathways, mechanisms, and relevant literature. Summarize findings into clear, structured reports and presentations for scientific and non-scientific audiences., • Collaborate across teams - Work closely with the Senior Project Manager to translate project scope into concrete computational tasks and timelines. Coordinate day-to-day with the Computational Biology and Data Science teams to align on pipeline usage, data requirements, and output quality. Present results in internal and external meetings. Anticipate risks and flag them early., • Support business development with ad-hoc analyses - Respond to prospect or partner requests that require quick biological or computational input: feasibility checks (e.g., “how many CRC PDOs do we have with KRAS G12D and what are the variants?”), literature-backed PoC analyses (e.g., isoform prevalence across a PDO cohort, pathway enrichment on a specific target), or data extractions to support incoming scope-of-work discussions. Who you are • A rigorous computational biologist who understands disease biology deeply enough to interpret results in their clinical context - and translate them into actionable deliverables., • Pragmatic and results-oriented - you'd rather deliver a defensible answer on time than a perfect one late., • Comfortable taking ownership of deliverables end-to-end and working under tight timelines without compromising quality., • A clear, structured scientific communicator - written and oral - who adapts naturally to both technical and non-technical audiences. Required qualifications • Master’s degree in Engineering, Computational Biology, Bioinformatics, or a related quantitative field. A PhD in Computational Biology, Systems Biology, Cancer Biology, or a related discipline is a strong plus., • Hands-on experience analysing omics data with a strong attention to detail and quality — ideally gained in industry or in collaborative translational research projects with external stakeholders., • Strong computational skills: proficient in Python and/or R, able to run, adapt, and troubleshoot existing analysis pipelines and workflow managers., • Fluency in English. Preferred qualifications • Prior experience in pharma, biotech, or CRO environments with client-facing delivery expectations., • Familiarity with AI-assisted analysis or coding workflows (e.g., LLM-based coding assistants, automated literature search)., • Previous exposure to oncology data or projects (e.g., drug response profiling, biomarker discovery, patient-derived models, translational oncology workflows)., • A track record of delivering quality work in time-constrained, multi-stakeholder settings. Interested? Apply and we will be in touch!