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Job Title: Vice President, Clinical Affairs Location: London, UK (Hybrid – 2 days per week onsite) Job Type: Permanent About the Role We are seeking a seasoned and strategically minded Vice President of Clinical Affairs to lead the global clinical development function for an innovative Class III cardiovascular medical device portfolio. This is a critical executive role, operating at both board and operational levels, responsible for shaping clinical strategy, advising senior leadership, and ensuring the successful design and execution of complex clinical programs—from first-in-human through pivotal trials. This position requires a highly experienced clinical leader who can confidently navigate the nuances of early feasibility studies, first-in-human trials, and pivotal study design, particularly within cardiovascular and implantable device environments. Key Responsibilities • Define and lead global clinical strategy aligned with regulatory and commercial objectives, • Act as a trusted advisor to the Board and Executive Leadership Team on clinical development pathways, risk, and opportunity, • Design innovative and efficient clinical development plans, including feasibility, first-in-human, and pivotal trials, • Assess and advise on optimal geographies for early-stage trials (e.g., Netherlands, Australia), including regulatory, ethical, and operational considerations, • Evaluate opportunities to streamline development timelines, including combining or sequencing early-phase studies where appropriate, • Provide expert guidance on study design, endpoints, patient selection, and statistical methodologies for Class III cardiovascular devices, • Oversee clinical trial execution, ensuring quality, compliance, and timely delivery, • Collaborate closely with Regulatory Affairs to align clinical evidence generation with MDR, FDA, and global requirements, • Engage with investigators, key opinion leaders (KOLs), and clinical partners to build strong study networks, • Lead interactions with regulatory bodies and ethics committees as needed, • Build and lead a high-performing clinical affairs team and external partnerships (CROs, consultants), • Extensive experience in Clinical Affairs within the medical device industry, with a focus on Class III cardiovascular or implantable devices, • Proven track record designing and executing first-in-human, early feasibility, and pivotal clinical trials, • Deep understanding of global clinical and regulatory frameworks, including EU MDR and US FDA requirements, • Demonstrated experience advising executive leadership and Boards on clinical strategy and development pathways, • Strong expertise in trial design, including adaptive designs and efficient study sequencing, • Experience working with international trial sites, particularly in Europe and Australia, • Ability to critically assess and optimise clinical development order, timelines, and evidence generation strategies, • Experience in start-up or scale-up environments, • Familiarity with combining early-phase studies or innovative trial methodologies, • Strong network of cardiovascular investigators and clinical experts, • Competitive executive compensation and benefits package, • Opportunity to lead clinical strategy for groundbreaking cardiovascular technologies, • Direct influence at Board level and across global development strategy, • Collaborative, innovation-driven environment, • Hybrid working model with London office presence (2 days per week) If you are a visionary clinical leader with deep expertise in cardiovascular medical devices and a passion for bringing transformative therapies to patients efficiently and safely, we would love to hear from you.

Our client specialises in property, office investments, hospitality, and construction. They have assets valued up to £3billion. Now seeking an experienced Senior Design Manager on a permanent basis. The position will be based out of their head office in Uxbridge, West London. You will design lead a few projects ranging from £20m - £80m. You will have a Design Coordinator reporting into you for support and the position will report into the MD. This position is also offering career progression to Head of Design / Design Director within 12 - 18 months. They require this individual to be up to date with all the new building regulations. Ideally experienced on all RIBA work stages and specialist in stages 3-5. It is essential you have previous experience with a tier one developer or main contractor, CIAT registered and degree qualified ideally. In return, our client is offering a basic salary between £90k - £110k + full package and bonus system on top.

Operations Manager / Contracts Manager RC Frame & Groundwork Subcontractor - £30m turnover £120,000 - £130,000 + Bonuses + Benefits West London office with projects in London and around the South of England. About the Employer: With a head office based around West London, this RC frame & groundwork specialist currently turns over around £30 million per annum, with individual packages ranging from £1m up to £10m each. This company is privately owned with an MD who remains hands-on, making sure standards are maintained and the business continues to grow. The company has a strong team, with every member of the management structure working together towards common goals. The senior team quite often refer to the business as a well-oiled machine, where each cog has a vital part to play. They are proud of their ability to secure a lot of their work through repeat business, as clients prefer to come back to them to negotiate future projects rather than the business just having to win work at open tender stages with aggressive pricing strategies. This business has plans in place to grow to £50m turnover over the next 3 years, and they have the bank balance, client list, and capability to meet that target. About the Opportunity: As an Operations Manager within this team, your role will support the MD with running the construction side of all of the projects. You’ll be involved from preconstruction through to delivery. Good man management and operational skills need to be shown, along with building knowledge with regard to RC frames and groundworks. Each project will have a project manager on it, but your role will support these managers. You’ll need to problem solve, look ahead, manage labour and costs across multiple sites, all while maintaining client relationships and the company's brand. The MD of this business is looking for someone from a trades background who understands how to build RC frames and groundworks, and has the operational skills to manage multiple sites and multiple teams. You will be his right-hand person. The opportunity to progress into an Operations Director's role exists. About the Salary / Benefits: Packages are always based on individuals’ backgrounds and experience, but as a rough guide, I have been told to target people earning anywhere from £120,000 to £130,000 per annum. This can be broken down in a number of ways, and this business is open to people on a PAYE or self-employed basis (including limited companies). Bonuses are available, as well as the usual fringe benefits. About the Requirements: I am looking for an individual who started life on site in a trades position (i.e. in groundworks or formwork). Having progressed through management, you will be operating as a Contracts Manager or Operations Manager now and will be used to covering multiple live projects. You must come from this sector background and have gained this management experience while working in the subcontract concrete frame and groundwork market. About Me, Your Consultant: My name is Andrew Jackson, and I am one of the founding directors of Cityscape Recruitment Ltd. I have over 20 years of experience in civil engineering & construction recruitment, during which time, I have specialised in the niche sectors of concrete frames, groundworks, basement construction and demolition. So, what does that mean for you? It means I work with the vast majority of the groundwork & concrete frame businesses in the UK, and I can help not only introduce you, but I can give you up-to-date information on each of them, helping you make an informed decision so you can take your career forward. I’ve been doing this for a while now, and I’ve maintained a positive reputation because I don’t tell people lies. I tell them everything I know and then let them choose. My job is simply to get you the options, give you the information and then let you decide what feels right for you. How to Apply: I am more than happy to discuss these opportunities with you over the phone or face to face in a fully confidential manner (you can get to know me while I get to know you). And I know this is an incestuous sector, and I fully understand the importance of keeping things discrete. It would be ideal to see a copy of your CV to understand your previous experience and employment. In line with GDPR laws, nothing will be done with your CV/details until we have discussed the role in detail anyway, but having gained an understanding of your formal past, this may help when we come to discuss options. My contact details are listed below: Email (remove all spaces): Andrew @ cityscape ltd . com

BOOKKEEPER - LOVLEY FAMILY RUN BUSINESS MAPLE CROSS SALARY CIRCA £40K DEPENDING ON EXPERIENCE Our client is a small family run construction company. They now require a Bookkeeper to join their team based in Maple Cross. Job Purpose Full time Book keeper office-based role. Construction industry knowledge and previous experience in a similar role essential. Role & Responsibilities • Manage all aspects of the purchase & sales ledger through Xero software, • Manage purchase orders and goods received, • Receive and process purchase invoices, • Monthly supplier payments, • Manage invoice queries with suppliers, • Weekly labour time sheet preparation & CIS management, • Weekly wages payments, • Liaison with external company accountants, • Monitor company email inbox, • General office admin, scanning and filing duties, • General admin assistance to site teams & MD Experience / Skills • Good IT skills, • Working within a similar role within the construction/industrial industry would be highly advantageous, • Confident communicator with staff and external bodies, • Excellent organisation skills with understanding of discretion and responsibility for important documents If this position is of interest and you possess the skills and experience outlined above, please attach your cv for the attention of Anna Maguire. Whilst we will endeavour to contact you following your response, occasionally due to the high volume of applications this cannot always be possible and we are only able to contact shortlisted candidates. We will keep your details on file and may contact you with future opportunities

Salary: £30,000 - £38,000 depending on experience and qualificationsLocation: AylesburyContract: Full time, PermanentWe are seeking a skilled and motivated automotive technician/mechanic to join our established team at M D Auto Care Ltd, Rabans Close, Aylesbury, HP19 8RS.A normal day will involve

A leading recruitment agency is seeking an experienced Air Conditioning Engineer to install, service, and maintain a wide range of air conditioning systems.The role requires NVQ Level 2 or 3 in Refrigeration & Air Conditioning and F-Gas Certification.Strong fault-finding skills and the ability to wo

A leading investment bank is seeking a proactive Executive Assistant to support its Senior Managing Director.Key responsibilities include managing diaries, organising high-level client events, and assisting in meetings.The ideal candidate should have experience in financial services, advanced skills

A forward thinking large format digital print & signage specialist is on the search for a Sales Director who could grow into a Managing Director’s role.A truly exceptional opportunity to join an organisation that has gone from strength to strength.Its ever‑expanding client base comprises local &

A recruitment agency is seeking an experienced Personal Assistant to support the Managing Director in a fast-paced FMCG environment.You will manage a complex diary, prepare quality documents, and coordinate travel logistics across two Midlands locations.This full-time role requires 3+ years of PA ex

Job Title: Sales Director – Managing Director Designate.This position has now been filled, but has been left on our website as we have other similar vacancies to this on an ongoing basis that might interest you.More importantly, we have vacancies that are not advertised due to their confidential n

A leading executive search firm is seeking a Managing Director to lead a global in-house agency.This role requires a transformative leader with senior leadership experience in creative and media sectors.Responsibilities include defining agency strategy, overseeing a high-performance culture, and dri

A leading professional services firm in the UK is looking for a Senior Leadership role to build and scale the Microsoft Application Evolution Services (AES) offering.The successful candidate will lead complex opportunities, embed services into transformation programs, and influence senior stakeholde

PA to MD and Team for City Investment Bank £30 per hour.

A global advisory firm in Greater London is seeking a Managing Director to lead its Forensic, Litigation & Valuation practice.The successful candidate will focus on expanding the firm's presence, providing expert guidance, and ensuring high client satisfaction.This role requires at least ten years o

A leading property management company in the UK seeks an experienced Senior Property Manager to oversee residential buildings, ensuring exceptional service delivery.The role involves managing day-to-day operations, supporting junior team members, and aligning with industry standards.Responsibilities

Director/MD in the Mergers & Acquisitions team.

Lead the International Side of the Digital Wealth Revolution!.Internationally, ETF adoption is accelerating through savings plans, neo brokers and mobile first platforms.State Street Investment Management is building a dedicated Direct Retail and Digital Wealth growth engine to embed our ETF capabil

A leading property management firm in the United Kingdom is seeking a Head of Freehold Property Management / Senior Property Manager to oversee their residential freehold portfolio.The role involves leading strategic and operational management, ensuring compliance, and providing exceptional customer

Candidates should have at least 5 years of experience in the AV MDU market and be proficient in AutoCAD.

A leading design and build specialist is looking for a Managing Director to launch and grow a new Higher Education division.This role includes full P&L responsibility, developing strategies, and building a strong market presence.The ideal candidate will have proven experience in the Higher Education

A premier global hospitality group based in London is seeking a Managing Director to oversee operations and lead new venue launches globally.This role requires proven experience in premium hospitality sectors and knowledge of both UK and US markets.Candidates should be financially savvy, have except

A leading financial services firm in London’s West End seeks a high-caliber Senior Executive Assistant to support a Managing Director and the senior team.This dynamic role requires over 7 years of EA experience in financial services, exceptional organizational skills, and a professional demeanor.R

A respected property consultancy in Central London is looking for a talented Personal Assistant to support the Chairman and Managing Director.This hybrid role emphasizes strong organizational and interpersonal skills to manage multiple responsibilities and provide high-quality administrative support

A leading recruitment firm is seeking an Executive Assistant to support a Managing Director and the wider team within a prestigious investment bank.This hybrid position offers a collaborative environment where you will manage complex diaries, coordinate international travel, and ensure seamless day-

Job Description: Cyber Consulting Director / MD.

A leading infrastructure consulting firm is seeking a Managing Director / EMEA Regional Leader to drive growth in its Infrastructure Advisory business across Europe and the Middle East.The role demands a visionary leader with over 10 years of experience in business development and client engagement,

A leading global financial services company is seeking a Managing Director for Sponsor Coverage in EMEA.This role involves strategic leadership and oversight for joint ventures and partnerships with sponsor clients, focusing on profitability and complex, cross-product structured solutions.Candidates

MD, EMEA Senior Sector Lead page is loaded## MD, EMEA Senior Sector Leadlocations: London, United Kingdomtime type: Full timeposted on: Posted Todayjob requisition id: R260041Position OverviewWe are seeking a highly experienced and dynamic Managing Director to lead a Sector Coverage Team

Une société de recrutement exécutif cherche un Directeur Général pour diriger les opérations de recrutement spécifique à ServiceNow.Le candidat idéal doit avoir plusieurs années d'expérience en recrutement exécutif, des compétences en direction d'équipe, et une expérience entrepreneur

A leading US Investment Bank is looking to strength its ECM team with additions at the Analyst, VP, D and/or MD level in Europe.

German Speaking Customer Representative (Remote) – Relocation to Greece.Exciting Remote Position! Are you a fluent German speaker ready for a new adventure?.German Speaking Customer Representative.Offer exceptional customer support to our German-speaking clients through phone, email, and chat.Deve

A leading signage and graphics company in Greater London is looking for a hands-on leader to guide their established business.The role requires strategic oversight across various departments, leveraging a multi-faceted background in sales, account management, and production.The ideal candidate will

AV Technical Design Consultant / Estimator - MDUs - This is a newly created position that is looking for someone that has a min of 5 years experience within the AV MDU market place. AV A-V A/V AUDIOVISUAL AUDIO-VISUAL AUDIOVISUAL CEDIA MDUS MDU COMMERCIAL DESIGN DOCUMENTATION COSTINGS SMARTOME AUTOM

A leading recruitment firm is looking for a Divisional MD for a multi-million turnover manufacturing business in Bedford, UK.