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Large Scale Chemist 📍 Onyx Scientific | Pharmaceutical CDMO | Location: Sunderland |Full-time | Permanent Are you a chemist looking for a hands-on role where you can apply your technical expertise at scale and make a tangible impact? At Onyx Scientific, we partner with academic, biotech, and pharmaceutical organisations worldwide, providing high-quality scientific support from early discovery through to commercial manufacture. Due to continued growth, we're looking for GMP Chemists to join our commercial manufacturing team. The Role As a Large Scale Chemist, you will play a central role in scale-up activities, operating reactors in the 50L–100L range while working in line with company safety standards and SOPs. You will support the delivery of reliable, high-quality outputs and collaborate closely with colleagues across the business. Key Responsibilities • Perform kilo-scale chemistry with minimal supervision, • Operate large-scale reactor processes safely and effectively, • Maintain a high standard of cleanliness and housekeeping, • Write weekly reports with support and guidance, • Review completed documentation for accuracy and compliance, • Identify and report issues relating to paperwork or documentation, • Comply fully with company SOPs and training requirements, • Communicate delays, challenges, or issues clearly and constructively The role may involve shift work at a future date. About You We're looking for an enthusiastic and detail-oriented chemist who enjoys practical laboratory and manufacturing work within a structured, regulated environment. You'll be committed to working safely, maintaining high-quality standards, and ensuring documentation is completed accurately and on time. You'll be comfortable working both independently and collaboratively while contributing positively to team objectives. Essential Skills and Experience • Degree in Chemistry or a related scientific discipline., • Strong understanding of chemical techniques and laboratory practices., • Experience working safely in laboratory or manufacturing environments., • Excellent attention to detail, particularly relating to documentation and compliance., • Strong organisational and time-management skills., • Effective communication and interpersonal skills., • Commitment to Health, Safety and Environmental requirements., • Ability to follow procedures accurately and work within regulated systems. Desirable Experience • Experience of kilo-scale or large-scale chemical processing, • Exposure to GMP-regulated environments, • Experience working within manufacturing, scale-up, or pilot plant operations, • Experience with advanced chemical processes such as gas reactions or air-sensitive chemistry, • Familiarity with SOP-driven quality systems and documentation requirements What You'll Bring • A proactive and self-motivated approach, • Strong organisational and prioritisation skills, • Exceptional attention to detail, • Problem-solving ability and a continuous improvement mindset, • Flexibility and adaptability to meet operational requirements, • A collaborative attitude and willingness to support colleagues across teams, • A positive and enthusiastic approach to contributing to team success What We Offer 🧪 The opportunity to work on meaningful manufacturing and scale-up projects 🤝 A supportive and collaborative scientific environment 📈 Career development within a growing pharmaceutical CDMO Benefits ✨ Company events 🚲 Cycle to work scheme 🧠 Health & wellbeing programme 🛡 Life insurance 🏥 Private medical insurance 🚗 Free on-site parking 👉 If you're passionate about chemistry and keen to make a meaningful contribution within a collaborative GMP commercial manufacturing environment, we'd love to hear from you. Apply today to join the Onyx Scientific team.

Mechanical Technician – Chemical Manufacturing (Sunderland) A leading chemical manufacturing site in Sunderland is seeking an experienced Mechanical Technician to join its engineering team. This is a hands-on role suited to someone with strong mechanical expertise, experience in hazardous environments, and a commitment to high safety and operational standards. The Role Reporting to the Engineering Manager, you will be responsible for maintaining, repairing, and installing a wide range of mechanical equipment across the site. You’ll play a key role in ensuring plant reliability, safety, and efficiency, working both independently and alongside the wider engineering team. Key Responsibilities Carry out maintenance, repair, installation, and commissioning of mechanical plant equipment Ensure all work complies with health, safety, environmental, and statutory requirements Use CMMS systems to manage, record, and complete maintenance tasks Diagnose faults, perform root cause analysis, and implement effective solutions Support planned shutdowns, projects, and continuous improvement initiatives Work within permit-to-work systems, ensuring proper risk assessments and isolations are in place Assist with project work, including installation, commissioning, and handover of new equipment Maintain high housekeeping standards and promote a positive safety culture Report defects, near misses, and unsafe conditions promptly Support and mentor colleagues where required About You Proven experience in a mechanical maintenance role within a chemical, process, or heavy industrial environment Knowledge of hazardous area working practices (CompEx Mechanical preferred) Experience working under COMAH regulations or similar high-hazard industries Strong understanding of health, safety, and environmental legislation Experience using CMMS systems for maintenance planning and reporting Ability to read and interpret technical drawings and documentation Proactive, flexible, and able to respond to breakdowns and operational needs What’s on Offer Competitive salary and benefits package Opportunity to work in a high-performing, safety-focused environment Ongoing training and development Exposure to complex plant systems and engineering projects Additional Information Flexibility required for overtime, call-outs, and shutdown periods * Involvement in emergency response and incident support as needed If you’re a skilled Mechanical Fitter looking to work in a dynamic and safety-critical environment, we’d like to hear from you

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Talent STEM is supporting an Energy-from-Waste operator with the appointment of a Production Shift Manager. This is a hands-on operational management position within a 24-hour process facility. You will be responsible for the safe, efficient and compliant operation of the plant during your shift, coordinating production, plant performance, maintenance support, safety systems and environmental compliance. The role You will take operational control of the facility during your shift, ensuring the plant remains within safe operating limits and delivers against agreed production and performance targets. Responsibilities will include: Managing the safe and efficient operation of the Energy-from-Waste facility Coordinating waste processing, combustion, boiler, steam and turbine operations Monitoring plant performance through the DCS and responding to abnormal operating conditions Managing plant start-ups, shutdowns and operational recovery activities Operating and managing permit-to-work and safe systems of work Coordinating maintenance activity to minimise disruption and operational losses Ensuring emissions and environmental permit requirements are met Managing shift resources, competence, training and succession planning Managing and developing the production shift team Supporting incident investigations, continuous improvement and operational projects Liaising with maintenance teams, contractors and external service providers Maintaining accurate operational records and effective shift handovers About you Direct Energy-from-Waste experience is essential. Due to the technical requirements of the position, applications can only be considered from candidates with direct operational experience within an Energy-from-Waste or waste-incineration facility. You should have: Proven shift-based operational experience within Energy from Waste Strong knowledge of waste combustion and incineration systems Experience operating boilers, steam systems and turbine generation equipment Experience managing plant through a DCS or control-room environment Previous people-management or operational supervisory responsibility Experience of permit-to-work systems and safe systems of work A strong understanding of emissions control and environmental compliance The ability to manage plant issues calmly and make sound operational decisions At least five years’ relevant operational experience At least two years’ people-management experience An HNC or HND in a technical, engineering or process-related discipline would be advantageous. Significant directly relevant experience will also be considered in place of formal qualifications. The opportunity This is an opportunity to take on a key operational management position within a complex Energy-from-Waste facility. You will join a business with a strong focus on safety, environmental compliance, plant performance and continuous improvement. The total package is £58,500–£63,700, inclusive of shift allowance. Applicants must have the unrestricted right to work in the UK. Unfortunately, this role is not eligible for visa sponsorship, and we are unable to consider applicants who require sponsorship now or in the future. To apply, submit your CV or contact Talent STEM for a confidential discussion. Talent STEM is a specialist recruitment consultancy supporting the scientific, engineering, chemical, pharmaceutical, manufacturing, environmental, biotechnology, FMCG and medical device sectors across the UK. Talent STEM Limited acts as an employment agency for permanent recruitment

QA Technician Location: Seaham Job Type: Full-timeWe are seeking a QA Technician to assist the Quality Assurance Supervisor in maintaining, verifying, and monitoring the Food Safety, Quality Systems, and Product Quality within our business. This role is crucial for meeting internal, customer, and third-party requirements and promoting a Quality Culture within the company. Day-to-day of the role: Carry out verification and monitoring of the production process according to the Quality and Food Safety Plan. Conduct sample collection, testing, and relevant corrective action for Shelf life monitoring, Microbiological and Chemical Testing, and Organoleptic Assessments, ensuring results are recorded appropriately. Act as a Quality and Food Safety Champion, maintaining high levels of GMP and GLP, communicating potential issues effectively, and working with the production team to reduce customer complaints. Ensure traceability throughout the production process and complete accurate, legible records. Investigate customer complaints thoroughly, identify Root Causes, and collaborate with the production team to implement preventive actions. Verify equipment according to the Calibration Plan, maintain neat legible records, and report equipment out of tolerance. Ensure that Production and QA records are verified and easily retrievable at all times.Required Skills & Qualifications: Education in Food Science or equivalent. Minimum Level 3 Hygiene certification. Basic Health and Safety knowledge. Understanding of HACCP principles. Experience in internal auditing and working with confidential information. Proficiency in Microsoft Word, Excel, PowerPoint, and Outlook. Strong command of English.Working Conditions: Fast-moving, highly automated environment based on the shop floor with some laboratory and administration tasks. Mainly a dry warm environment, but some areas can be cold. Awareness of noise pollution and various manufacturing hazards is necessary. The role requires long periods of work unsupervised and under own initiative.Challenges: Managing multiple tasks and maintaining quality standards even during frequent line issues, such as problems with metal detectors. Demonstrating versatility in handling a wide range of tasks including raw material testing, analytical testing, quality and food safety monitoring, and more. Implementing root cause and preventive actions effectively within time constraints.Working Relationships & Contacts: Internal: Production, NPD (New Product Development), Warehouse, Hygiene. External: Customers, external laboratories, Suppliers.Benefits: Competitive salary and benefits package. Opportunities for professional growth and development in a supportive environment