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Role Overview In this project, you will leverage your expertise in internal medicine to help fine-tune large language models (like ChatGPT). Your deep understanding of diagnostic reasoning, chronic disease management, and patient care will help ensure AI systems deliver accurate, empathetic, and safe medical reasoning. What You’ll Do • Design and solve advanced clinical scenarios reflecting internal medicine practice, from complex differential diagnoses to chronic care management., • Evaluate AI-generated responses for diagnostic accuracy, clinical judgment, and evidence-based reasoning., • Identify gaps in AI understanding across internal medicine subspecialties., • Collaborate with AI researchers and medical peers to improve model quality and reliability., • Provide structured, expert feedback that informs next-generation AI development for clinical and educational applications. Candidate Requirements • MD or equivalent; active practice within the last 3+ years., • Board certification or equivalent qualification in Internal Medicine., • Strong grasp of internal medicine’s full spectrum — acute care, chronic disease, and preventive medicine., • Skilled in articulating complex medical reasoning in clear, patient-friendly language., • Excellent written and spoken English; familiarity with digital medical tools is a plus., • Education from a top-tier institution (e.g., Harvard, Stanford, UCSF, Oxford, etc.). Offer Details • Commitment: 20–40 hours/week (minimum 4 hours/day, with overlap in PST), • Engagement: Contractor/freelancer (no medical or paid leave), • Duration: 1 month, with possible extension, • Remote: Fully remote, collaborative environment About Turing Based in San Francisco, California, Turing is the world’s leading research accelerator for frontier AI labs and a trusted partner for global enterprises deploying advanced AI systems. Turing supports customers in two ways: first, by accelerating frontier research with high-quality data, advanced training pipelines, plus top AI researchers who specialize in coding, reasoning, STEM, multilinguality, multimodality, and agents; and second, by applying that expertise to help enterprises transform AI from proof of concept into proprietary intelligence with systems that perform reliably, deliver measurable impact, and drive lasting results on the P&L. After applying, you will receive an email with a login link. Please use that link to access the portal and complete your profile. Know amazing talent? Refer them at ___, and earn money from your network.

Clinical Trial Consultant The Scientific Team at Russell Tobin / Pride Health is hiring an Pharmacovigilance Specialist for a top pharmaceutical organization near Cambridge, MA. Responsibilities • Triage, Intake, case entry and QC of ICSRs originating from Biogen sponsored studies or other assigned cases, • Includes narrative writing, MedDRA coding, drafting of follow-up queries and event notifications to internal stakeholders, • Perform retrospective quality checks on processed cases, • Independently manage assigned cases, accounting for weekends and holidays, to deliver cases to internal stakeholders on time and ensure case completion allowing for on-time regulatory reporting, • Review and resolution of reconciliation issues between the clinical and safety databases per in collaboration with Data Management, • Provide investigation details into late regulatory reporting of CT cases Requirements • Bachelor’s degree in science or healthcare related field, • 4+ years expeirence in pharmacovigilance, • Knowledge of Global and local safety regulations, • Excellent written and verbal communication skills, • Experience in ICSR processing in safety database systems such as ArisG, Argus and Veeva, • Understanding of global safety reporting regulations and guidelines including the FDA, ICH, and EU Regulations and Requirements for Pharmacovigilance, • Strong computer skills within Microsoft suite of programs (Word, Excel, PowerPoint, and Outlook), • Knowledge of medical and clinical practices and a strong understanding of medical concepts and terminology required Additional Details: • Onsite position, • Position Type: contract position through the end of the year with potential for extension, • Salary range approved: $50-60/hr depending on experience Must be authorized to work in the United States. APPLY NOW! Pride Global and its affiliates, including Russell Tobin, Pride Health, Pride Now, and Pride One, offers eligible employee’s comprehensive healthcare coverage (medical, dental, and vision plans), supplemental coverage (accident insurance, critical illness insurance and hospital indemnity), 401(k)-retirement savings, life & disability insurance, an employee assistance program, legal support, auto, home insurance, pet insurance and employee discounts with preferred vendors. Equal Employment Opportunity Pride Global and its affiliates are an equal opportunity employer. We do not discriminate on the basis of the race, religious creed, color, national origin, ancestry, physical disability, mental disability, reproductive health decision making, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, age, sexual orientation, veteran or military status, or any other characteristic protected by applicable federal, state, or local law. Fair Chance Employment Pride Global and its affiliates are a Fair Chance employer. We consider all qualified applicants, including those with criminal histories, in a manner consistent with applicable state and local Fair Chance laws and ordinances, including, the California Fair Chance Act and all applicable local Fair Chance ordinances. Accommodations We are committed to providing reasonable accommodations to applicants and employees with disabilities. If you require reasonable accommodation to participate in the application or interview process, or to perform the essential functions of this role, please contact us. Only applicable for San Francisco Candidates: Under the San Francisco Lactation in the Workplace Ordinance, we will provide written notice of lactation accommodation rights, and this notice will automatically be given upon hiring, any inquiry of parental leave or lactation accommodation. #PHC #LI-LG1 #phc-zr #JD-SCIENCE

Novogene is a leading global provider of genomic services and solutions. Leveraging the latest next-generation sequencing (NGS), bioinformatics expertise, and the largest sequencing capacity in the world, Novogene provides unsurpassed data quality and fast turnaround time to all our customers. We are seeking a proactive and data-driven Bioinformatics Specialist to join our Cambridge Team. This role is highly collaborative and requires drive, organisation, and foundational analysis skills. You will work closely with different business sectors and deliver project data analysis to support business growth. You are expected to support pipeline optimisation and support the team achieve higher goals. The successful candidate must be willing to commute to our Cambridge office when required. Job description: • Responsible for data analysis and result delivery for projects related to research and clinical services in Novogene's European laboratories, ensuring accurate, efficient project execution and delivery., • Responsible for the maintenance, continuous optimization, and upgrading of data analysis pipelines and processes for clinical services, ensuring stable and efficient workflows that meet diverse requirements., • Responsible for ensuring project operations comply with all relevant regulatory and compliance requirements, while continuously improving and supporting related quality assurance activities., • Lead the resolution of BI-related pre-sale and after-sale issues. Attend customer meetings for BI troubleshooting to ensure customer satisfaction., • Prepare marketing materials for specific products and conduct technical training and market promotion activities (e.g., seminars, webinars). Skills required: • PhD in Biology, Medicine, or a related field with background in next-generation sequencing., • Minimum 1+ years of experience in an academic or industrial applied research environment involving biomedical data analysis., • Experience in a clinical or biopharmaceutical environment is preferred., • Proficient in using Linux/UNIX, Perl, R, Python, etc., • Strong logical thinking, problem analysis, and problem simplification abilities., • Excellent presentation, communication, and teamwork skills. Fluent in written and spoken English and Mandarin., • Strong pressure management skills; comfortable with short-term business travel. All employment decisions at Novogene are based on business requirements on its positions and skill sets on applicants. The business is committed to providing an inclusive and accessible recruiting experience for candidates with disabilities, or other physical or mental conditions. Our privacy policy:

I am seeking Occupational Health Technicians to join my client's expanding peripatetic team. In this role, you will be required to travel across the UK, driving a Mobile Medical Unit (MMU) to client sites to deliver high-quality health surveillance services. This is a varied and rewarding role that plays a vital part in ensuring the health and well-being of employees across a range of industries. This is a great opportunity for an enthusiastic and reliable individual to expand their skills and experience in a supportive environment, where you’ll be given a 3-week Training and Induction Programme with ongoing mentoring and support from the team. Key Responsibilities * Conduct health surveillance screenings, including audiometry, lung function testing, and baseline measurements such as height, weight, blood pressure, and urinalysis. * Accurately record all medical information in occupational health records and ensure it is passed to the relevant clinical staff. * Maintain and ensure all equipment is clean, serviceable, and fit for purpose. * Support health promotion activities and other additional tasks as required. * Assist the wider occupational health team by gathering and recording accurate information to support clinical decision-making. * Provide biometric data through screening procedures to enable nursing and physician staff to make informed clinical decisions regarding patient management. What ...

This job is with AstraZeneca, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly. Associate Director Integrated Bioanalysis -Biopharma Bioanalytical Program Lead Location: Cambridge Salary: Competitive Introduction to role: Are you ready to lead bioanalytical strategy that accelerates safe, transformative medicines to patients worldwide? As Associate Director based in Gothenburg, Sweden, you will shape the design and implementation of end-to-end bioanalysis across diverse modalities, translating complex data into clear program decisions that guide dose selection and clinical advancement. You will work at the heart of a collaborative, matrixed environment-partnering closely with lab-based scientists and global project teams to build robust, compliant assays and deliver decisive PK/CK, PD, immunogenicity, and target engagement insights. Can you see yourself aligning innovative assays with program milestones to increase confidence and speed through development? You will also engage with leaders across discovery, safety, clinical pharmacology, translational science, toxicology, and regulatory, with opportunities to represent our science externally. This role is highly visible and ideal for a scientist who thrives on impact, rigor, and cross-functional influence. Accountabilities: Bioanalytical Strategy Leadership: Define and drive integrated bioanalytical strategies for multiple therapeutic modalities, aligning assay plans with program milestones, dose selection, and decision endpoints to strengthen portfolio progression. Experimental Design Partnership: Collaborate with lab-based scientists to shape experimental design, controls, and assay selection that deliver reliable PK/CK, PD, immunogenicity, and target engagement readouts. Assay Development and Tech Transfer: Oversee assay development, qualification/validation, and transfer to internal and external labs to ensure reproducibility, scalability, and compliance. Regulatory Interface: Prepare and review regulatory documentation; interact with global Health Authorities to address questions, mitigate risks, and enable clinical progress. Cross-Functional Influence: Lead within a matrix environment to integrate bioanalysis across safety, clinical pharmacology, toxicology, translational science, and project teams for cohesive program strategy. Risk Management and Quality: Anticipate analytical pitfalls, set data quality standards, and implement controls consistent with regulated bioanalysis to secure decision-ready data. External Representation: Present scientific findings internally and externally, contribute to publications, and represent AstraZeneca in scientific forums and consortia. Portfolio Impact: Convert bioanalytical insights into dose decisions and development acceleration, improving the probability of clinical success for patients. Essential Skills/Experience: * BSc/MSc in relevant subject with extensive experience in Bioanalysis or PhD in relevant subject with strong experience in Bioanalysis required * Proven experience as a Subject matter Expert in regulated bioanalysis across a range of modalities PK/CK, PD and immunogenicity assessments (humoral and cellular) * Experienced as a bioanalytical lead in diverse project teams, defining, leading and implementing robust bioanalytical strategy to advance the portfolio including Biomarker & Target Engagement strategy for dose decision endpoints. * Skilled scientist able to discern the advantages and pitfalls of a range of analytical techniques such as molecular assays (ddPCR, qPCR, RT-qPCR), flow cytometry, ELISpot, viral assays, cytokine assays, ligand binding assays and Mass Spectrometry. * Deep understanding of small & large molecule Bioanalysis * Experienced in regulated bioanalysis for multiple drug modalities. * Demonstrable experience in PD Biomarker & Target Engagement assays * Proven publication and presentation record * Exceptional verbal and written communication skills Desirable Skills/Experience: * Experience of working in a matrix environment * Knowledge of Immunology and or metabolic diseases Why AstraZeneca: This is where curious minds are empowered to follow the science and push boundaries with courage and care. We bring unexpected combinations of experts together face to face several days a week to ignite bold ideas and move fast. By blending cutting-edge biology with data, technology and AI, we pioneer new approaches that better predict clinical success and advance therapies across complex diseases. You will join a collaborative culture that values kindness alongside ambition, where your contribution directly shapes the future of healthcare and the speed at which life-changing medicines reach patients. What is next ? Bring your bioanalytical leadership to a place where it will matter, submit your combined CV and cover letter by 17th May 2026 to help deliver decisive science that reaches patients faster! Salary: Negotiable

This job is with Gilead Sciences Inc., an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly. At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Associate Director, Patient Safety provides strategic pharmacovigilance leadership for one or more products, compounds, or indications across the development and/or post marketing lifecycle. This role contributes safety expertise to ensure continuous evaluation of benefit-risk profiles, regulatory compliance, and patient safety, while serving as a key Patient Safety representative on cross functional teams. The Associate Director operates with a high level of autonomy, partnering across functions to support product development, lifecycle management, and post authorization safety activities. Key Responsibilities * Provide scientific input into pharmacovigilance activities, including safety surveillance, signal detection and evaluation, and benefit-risk assessments for assigned products and assisting with pharmacovigilance activities for other products when needed. * Contribute to the development and execution of safety strategies across the product lifecycle, from clinical development through post‑marketing. * Provide input into aggregate safety reports (e.g., PSURs/PBRERs, DSURs), regulatory submissions, and responses to health authority inquiries. * Support risk management activities, including Risk Management Plans, risk minimization measures, and safety‑related labeling updates. * Provide safety leadership and review of clinical study protocols, amendments, and study‑related documents. * Serve, where applicable, as a medical monitor for post‑authorization, Phase 4, or observational studies, including investigator‑initiated and collaborative research. * Represent Patient Safety on cross‑functional teams, collaborating with Clinical Development, Regulatory Affairs, Medical Affairs, RWE/HEOR, and other functions. * Ensure pharmacovigilance activities are conducted in compliance with global regulations, internal SOPs, and quality standards. * Contribute to inspection readiness, process improvement initiatives, and the ongoing enhancement of Patient Safety operating models. * Build effective working relationships and provide thoughtful safety input to internal stakeholders to support patient‑centric decision‑making. Basic Qualifications * Advanced degree in a scientific or medical discipline (e.g., MD, PharmD, PhD, or equivalent). * Relevant experience in pharmacovigilance / patient safety within the pharmaceutical or biotechnology industry. * Working knowledge of global pharmacovigilance regulations and aggregate safety reporting requirements. * Demonstrated ability to evaluate safety data, apply clinical judgment, and communicate benefit-risk considerations. * Experience working effectively in cross‑functional, matrix environments. Preferred Qualifications * Experience supporting safety oversight for products across multiple stages of the development or post‑marketing lifecycle. * Prior involvement in safety signal evaluation, risk management activities, and regulatory interactions. * Strong written and verbal communication skills, with the ability to present complex safety information to diverse stakeholders. * Ability to manage multiple priorities and products concurrently in a fast‑paced environment. It is the policy of Gilead Sciences, Inc. and its subsidiaries and affiliates (collectively "Gilead" or the "Company") to recruit select and employ the most qualified persons available for positions throughout the Company. Except if otherwise provided by applicable law, all employment actions relating to issues such as compensation, benefits, transfers, layoffs, returns from layoffs, company-sponsored training, education assistance, social and recreational programs are administered on a non-discriminatory basis (i.e. without regard to protected characteristics or prohibited grounds, which may include an individual's gender, race, color, national origin, ancestry, religion, creed, physical or mental disability, marital status, sexual orientation, medical condition, veteran status, and age, unless such protection is prohibited by federal, state, municipal, provincial, local or other applicable laws). Gilead also prohibits discrimination based on any other characteristics protected by applicable laws. Please apply via the Internal Career Opportunities portal in Workday.

This job is with AstraZeneca, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly. Job Title Senior Scientist - Genetic Toxicology Location: Cambridge Salary: competitive Introduction to role Based in our Discovery Centre on the Cambridge Addenbrookes campus, this Senior Scientist role sits at the heart of Genetic Toxicology, working alongside colleagues in Clinical Pharmacology and Safety Sciences to advance the genotoxicity assessment of new medicines. The position focuses on high-throughput imaging and screening methodologies to generate robust, decision-enabling data that informs safety assessment across drug discovery and development. Operating in a highly collaborative environment, this role combines hands-on scientific delivery, strategic assay optimisation, and data-driven insight to help shape the next generation of therapeutics. Ready to ask bold questions and follow the science? Accountabilities: * Lead the design, execution, and interpretation of high-content imaging and other genotoxicity assays to support projects from early discovery through development. * Drive optimisation and innovation in imaging-based and complementary genetic toxicology methodologies, enhancing throughput, robustness, and biological relevance. * Apply advanced data analysis and visualisation approaches to integrate complex datasets and communicate clear conclusions to multidisciplinary teams. * Interpret and apply ICH S2(R1), OECD, and pharmaceutical regulatory expectations to ensure studies are designed and delivered to support regulatory submissions. * Oversee non-GLP genotoxicity studies with CROs and external partners, ensuring scientific quality, compliance with internal standards, and timely delivery of milestones. * Prepare high-quality study reports and technical documentation, maintaining rigorous data integrity and documentation practices. * Provide scientific leadership within the Genetic Toxicology Group, contributing to strategy, mentoring colleagues, and supporting training and SOP development. * Engage with internal teams, consortia, CROs, and academic collaborators to bring emerging science into practice and strengthen our genetic toxicology capabilities. * Troubleshoot assay and study challenges using sound scientific judgement, keeping programmes on track under tight timelines. Influence project decision-making by translating genetic toxicology findings into clear risk assessments and recommendations. Essential Skills/Experience * PhD in Toxicology or a related life science discipline, or equivalent industry experience, with hands-on expertise in genetic toxicology across drug discovery and development within the pharmaceutical industry. * Proven experience working to ICH S2(R1) and OECD guidelines for in vitro and in vivo genotoxicity studies, and assays including the micronucleus assays, with the ability to contribute to regulatory-ready submission packages. * Experience monitoring non-GLP genotoxicity studies, including protocol design, CRO/vendor oversight, milestone tracking, data review, deviation management, and inspection/audit readiness, while ensuring alignment with internal standards, external regulations, and compliance requirements. * Strong expertise in High Content Imaging assay development, data quality control, and analysis, with experience applying automation and digital workflows to improve throughput, robustness, and reproducibility. * Demonstrated ability to integrate data from multiple assays and translate findings into clear scientific conclusions and actionable genetic toxicology risk assessments for project teams. * Excellent written and verbal communication skills, with experience authoring study reports, contributing to technical documentation, and maintaining high data quality and documentation standards. * Demonstrated ability to challenge conventional approaches and apply fit-for-purpose scientific methods, while operating within internal governance, external compliance frameworks, and global regulatory requirements in the pharmaceutical industry. * Proven ability to deliver high-quality work to tight timelines, with strong skills in prioritisation, adaptability, and working across multiple projects. * Maintains current knowledge of advances in genetic toxicology and applies emerging science appropriately through collaboration with internal teams, CROs, consortia, and academic partners. * Strong problem-solving skills and resilience, using scientific judgement, logical analysis, and pragmatic solutions to address assay or study challenges and keep programmes on track. * Demonstrated teamworking and leadership capabilities, acting as a collaborative and inclusive colleague who supports mentoring, SOP development, training, and a high-performing team culture. Desirable Skills/Experience: * Experience working within a laboratory environment, preferably with a primary focus on toxicology science and with knowledge and experience of drug development. * Experience in providing design and interpretation of regulatory toxicology data. * Experience in Genetic Toxicology and its application in relation to Safety Assessment At AstraZeneca, science sits at the core of every decision: teams are empowered to explore complex disease biology in depth, fuse data science and technology with experimental innovation, and work across disciplines to move ideas from concept to clinic at pace. Colleagues collaborate closely with academia, biotechs and global partners, learning from both success and failure while tackling uncertainty with resilience and curiosity; this environment supports continuous development, open dialogue and bold thinking as we strive to transform treatment options for patients worldwide. SO, WHAT'S NEXT? We welcome your application no later than 10th May 2026 Where can I find out more? Follow AstraZeneca on LinkedIn Follow AstraZeneca on Facebook Follow AstraZeneca on Instagram Ready to make a difference? Apply now to join our team! Salary: Negotiable

If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description: The Global Safety Physician serves as the safety expert accountable for the global safety strategy and overall safety profile for Jazz Pharmaceuticals product/s (investigational and marketed) throughout their lifecycle. This includes supporting major pre- and post-marketing safety deliverables including signal, benefit-risk evaluation and risk management activities for specific products. This individual must effectively interface cross-functionally at all levels in the organization as well as with external Regulatory Authorities. This individual will work together with PV management to ensure the safety assessment of priority product/s, including review of aggregate safety analyses and scientific literature, preparing safety reports and communicating changes in the product risk profile to internal and external stakeholders. The ability to work in a dynamic, changing environment to meet corporate and patient needs is essential. Essential Functions Job Responsibilities and Requirements: Lead the preparation and review of safety-related section(s) for product/s. Documents include review of specific clinical, regulatory, and scientific documents including protocols, informed consent/assent forms, case report forms (CRFs), statistical plans, clinical study reports/synopses, integrated summaries of safety, New Drug or Biologic License Applications (NDA/BLA), Marketing Authorization Applications (MAA), Common Technical Document (CTD) submissions, Regulatory Agency responses, IRB/EC requests, briefing books, manuscripts/journal articles and other documents as needed, ensuring safety profile reflected for assigned product/s. Be a key member, as the safety representative, to a Global Regulatory Team and to a Core Development Team. Interface with Risk Evaluation and Mitigation Strategy (REMS) team to optimize risk management of assigned products from a PV perspective. Where relevant, support creation and maintenance of Company Core Safety Information (CCSI) and ensure implementation of CCSI in all Reference Safety Information (RSI) including Investigator Brochures (IBs), Company Core Data Sheet (CCDS), national labels and other associated product labeling. Support review of medical/scientific literature to identify literature relevant for signal detection activities and aggregate reporting for assigned product/s, as needed. Support signal detection activities to ensure signal identification, evaluation, validation, for assigned product including individual and aggregate data analyses; interpretation of safety signals and trends; documentation and communication of safety assessments (written and verbal) of safety risks in collaboration with CRSO and PV management. Participate in or Lead a Safety Management Team (SMT) for an assigned product. Contribute to the preparation and review of pre- and post- marketing aggregate safety reports IND Annual Reports, and 6-monthly Suspected Unexpected Serious Adverse Reactions (SUSARs) Line Listing Reports and ensure consistent communication of safety profile/topics across various regulatory safety documents for assigned product/s. Contribute to preparation of Risk Management Plans (RMPs) for assigned products ensuring identification of risks, appropriate risk minimization and effectiveness measures in accord with regulatory requirements. Provide guidance with adverse event (MedDRA) and drug (WHO Drug) coding for clinical and postmarketing safety data. Demonstrate or gain knowledge of current and applicable global PV regulations and guidelines (e.g., CIOMS, EMA, FDA, ICH, etc.), SOPs and quality standards. Provide safety expertise to due diligence activities, if/ as needed. Keeps abreast of new PV/safety regulations and guidance from the regulatory authorities. Required Knowledge, Skills, and Abilities Minimum Requirements Minimum 2-5 years of Clinical Development, Medical Affairs or Drug Safety/Pharmacovigilance experience; other relevant medical affairs experience may be considered. Excellent knowledge of drug development process. Requires a high level of initiative and independence. Must have excellent written and oral communication skills, resourcefulness and personal organization skills together with demonstrated cross-functional teamwork. Computer literacy with proficiency in external Regulatory Databases, Microsoft Excel, PowerPoint and Word. Some national/international travel may be required. Leadership Skills Enterprise and Proactive Mindset—demonstrate collaborative spirit, understanding the benefit of working with others cross functionally, in a dynamic environment. Set & Achieve Goals: Understand business objectives and effectively translate them into strategies, while skillfully navigating obstacles and resistance to change. Inspire & Mobilize Others: Serve as a positive role model – create followership and effectively mobilize and influence others, both on your teams and across the organization. Understanding of target product profile; clinical designs and/or global PV regulatory environment with working knowledge of international regulations, initiatives, standards and Good Clinical and Pharmacovigilance practices (GCP, GVP). Exposure to working relationship with the FDA, EMA and other regulatory authorities is preferred. Working knowledge of safety databases (ARISg, ARGUS, or other safety database applications) and electronic data capture systems a plus. MedDRA trained and working knowledge of MedDRA and WHO Drug coding dictionaries a plus. Ability to manage multiple tasks with deadlines in fast-pace environment. Required/Preferred Education and Licenses MD required; medical licensure in at least one region preferred; clinical research and/or fellowship training in internal medicine, oncology, neurology, or other relevant specialty is a plus. #LI-Remote Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. FOR US BASED CANDIDATES ONLY Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $(phone number removed) - $(phone number removed) Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis. At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here

If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. The Associate Director, Medical Safety (Scientist) is a key member of the Medical Safety team. This role is responsible for ensuring up to date processes / procedures for safety governance, signal management, clinical surveillance, periodic safety reporting, and risk management and/or driving innovation initiatives within Medical Safety organization. In close collaboration with Medical Safety Physician and/or Medical Safety Scientist line manager, this role is also responsible for contributing to regulatory submission safety strategy. Other responsibilities include but are not limited to: signal management activities, production of aggregate safety reports (e.g., DSURs, PADERs, PBRERs), provision of high-level scientific expertise in the safety evaluation and risk management strategies of assigned products (e.g, signal evaluation reports, health hazard evaluations, and RMPs), global leadership / representation of Medical Safety within the company (e.g., leading Safety Management Teams, presenting at Executive Safety Board meetings), and SME support for HA inspections. Essential Functions • Leads cross-functional safety management teams (SMTs) and drives safety strategy for responsible product/program., • Ensures that processes and procedures are up to date to meet regulatory requirements and inspection readiness, • Drives signal management process using available methodologies, including making recommendations for the assessment and prioritization of safety concerns., • Effectively communicates with members of the interdisciplinary team regarding ongoing signal evaluation., • Ensures that available safety information is evaluated in order to meet both internal and external requirements, including identifying the need for labeling updates. Produces accurate and fit for purpose evaluation documents with clear conclusions, as required., • Leads the coordination of aggregate safety reports (PBRERs, DSURs, PADERs) and authors relevant sections, as appropriate., • Authors or provides guidance for the production of risk management plans (RMPs)., • Provides strategic input into regulatory requests / responses., • Delivers clinical safety input into clinical development program., • Leads the medical safety contributions of global regulatory submissions for new products, formulations or indications., • Participates in and/or leads internal safety surveillance meetings as well as joint safety meetings with licensing partners, as needed., • Provides medical safety input into creation / review of Safety Data Exchange Agreements and/or other PV agreements., • Escalates issues / concerns to senior management in a timely and appropriate manner., • Mentors and trains junior members of the Medical Safety team. Required Knowledge, Skills, and Abilities Minimum Requirements • At least 6 years of experience in drug safety, including at least 4 years of experience in surveillance / risk management., • Ability to independently search clinical safety and literature databases for relevant information., • Expert knowledge of pharmacovigilance regulations regarding aggregate safety reports, risk management plans, and signal management., • Excellent medical writing skills, as well as proven ability to effectively lead interdisciplinary teams., • In-depth knowledge of medical and drug terminology, as well as the clinical development process., • Familiarity with MedDRA and safety databases; Proficient with Windows applications, and ability to learn new programs / databases. Required/Preferred Education and Licenses Requires a degree (e.g., BS, BA, MSc or PhD) or professional qualification in a life science field (e.g., nursing or pharmacy) or a relevant scientific/technical discipline and experience. #LI - Remote Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. FOR US BASED CANDIDATES ONLY Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $(phone number removed) - $(phone number removed) Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis. At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here

If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. 1 Essential Functions/Responsibilities The Associate Medical Director / Global Safety Physician is responsible for implementing the global safety strategy and monitoring the overall safety profile for Jazz Pharmaceuticals products (investigational and marketed) throughout its lifecycle. This includes generating all major pre- and post-marketing safety deliverables including signal, benefit-risk evaluation and risk management activities. This individual must effectively interface cross-functionally at all levels in the organization as well as with external Regulatory Authorities. This individual, under supervision from the Senior Medical Director in Medical Safety, will work together with PV staff in managing the safety assessment of products, including review of aggregate safety analyses and scientific literature, preparing safety reports and communicating changes in the product risk profile to internal and external stakeholders. The ability to work in a dynamic, changing environment to meet corporate and patient needs is essential. Provide Medical Safety/PV inputs to the assigned products at Jazz Pharmaceuticals, which may include Clinical Development program of all phases, Investigator Sponsored, Compassionate Use, and Disease Monitoring Programs; liaise with Clinical Sciences, Clinical Operations, Medical Affairs, Biometrics, Regulatory Affairs, Contract Research Organizations (CROs), Data Monitoring Committees (DMCs) and other entities to contribute to overall study execution while ensuring safety strategy and operational excellence Provide Medical safety/PV inputs to Jazz Pharmaceuticals Commercial organization to support global launch activities for assigned products Participate in the preparation and review of safety-related section(s) for clinical, regulatory, and scientific documents including protocols, informed consent/assent forms, case report forms (CRFs), statistical plans, clinical study reports/synopses, integrated summaries of safety, New Drug or Biologic License Applications (NDA/BLA), Marketing Authorization Applications (MAA), Common Technical Document (CTD) submissions, Regulatory Agency responses, IRB/EC requests, briefing books, manuscripts, journal articles and other documents as needed, ensuring safety profile reflected for assigned products Collaborate in the creation and maintenance of Company Core Safety Information (CCSI) and with the Jazz Labeling Committee ensure implementation of CCSI in all Reference Safety Information (RSI) including Investigator Brochures (IBs), Company Core Data Sheet (CCDS), national labels and other associated product labeling Perform review of medical/scientific literature to identify literature relevant for signal detection activities and aggregate reporting for assigned products, as needed Conduct signal detection activities to ensure signal identification, evaluation, validation, for assigned products including individual and aggregate data analyses; interpretation of safety signals and trends; documentation and communication of safety assessments (written and verbal) of safety risks in collaboration with key internal/external stakeholders Chair the Safety Management Team (SMT) of products under authority and participate in other executive forums for assigned products Serve as the signatory and overseer of the preparation and review of pre- and postmarketing aggregate safety reports including Periodic Safety Update Reports (PSURs)/Periodic Benefit Risk Evaluation Reports (PBRERs), Periodic Adverse Drug Experience Reports (PADERs), Development Safety Update Reports (DSURs), IND Annual Reports, and 6-month Suspected Unexpected Serious Adverse Reactions (SUSARs) Line Listing Reports and ensure consistent communication of safety profile/topics across various regulatory safety documents for assigned products Contribute to preparation of Risk Management Plans (RMPs) for assigned products ensuring identification of risks, appropriate risk minimization and effectiveness measures in accord with regulatory requirements Provide guidance with adverse event (MedDRA) and drug (WHODrug) coding for clinical and post-marketing safety data Demonstrate knowledge and ensure compliance with current and applicable global PV regulations and guidelines (e.g., CIOMS, EMA, FDA, ICH, etc.), SOPs and quality standards; active involvement in inspection readiness activities, internal audits and external inspections Represent PV in cross-functional forums and committees involving products under responsibility to achieve the Company’s goals Contribute to key performance indicators to ensure PV excellence Maintain knowledge of Jazz Pharmaceuticals indications for investigational and/or marketed products assigned Keeps abreast of new PV/safety regulations and guidance from the regulatory authorities 2 Required Knowledge, Skills, and Abilities Understanding of global PV regulatory environment with working knowledge of international regulations, initiatives, standards and Good Pharmacovigilance practices (GVP) including but not limited to Americas and European Union, territories including an understanding of case processing procedures and other pharmacovigilance processes Working knowledge of safety databases (ARISg, ARGUS, or other safety database applications) and electronic data capture systems MedDRA trained and working knowledge of MedDRA and WHO Drug coding dictionaries Working experience with PV audit process with active participation in Regulatory Authority Inspections is preferred Ability to manage multiple tasks with deadlines in fast-paced working environment Knowledge of drug development process Requires a high level of initiative and independence Must have excellent written and oral communication skills, resourcefulness and personal organization skills together with demonstrated cross-functional teamwork Computer literacy with proficiency in external Regulatory Databases, Microsoft Excel, PowerPoint and Word Some national/international travel may be required 3 Required/Preferred Education and Licenses MD required (or equivalent); medical licensure in at least one state preferred; clinical research and/or fellowship training in internal medicine or neuroscience, hematology/oncology or other relevant specialty is a plus Minimum 3 years of Drug Safety/Pharmacovigilance (PV) experience or 3 or more years clinical development experience. Other relevant experience may be considered #LI-Remote Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. FOR US BASED CANDIDATES ONLY Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $(phone number removed) - $(phone number removed) Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis. At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here

Company Description Genomics England is a global leader in enabling genomic medicine and research, focused on creating a world where everyone benefits from genomic healthcare. Building on the 100,000 Genomes Project, we support the NHS’s world-first national whole genome sequencing service and run the growing National Genomic Research Library, alongside delivering numerous major genomics initiatives. By connecting research and clinical care at national scale, we enable immediate healthcare benefits and advances for the future. Our mission is to provide the evidence and digital systems so that by 2035 genomics could play a role in up to half of all healthcare interactions, whilst securing the UK’s position as the best place to discover, prove and benefit from genomic innovations. We are accelerating our impact and working with patients, doctors, scientists, government and industry to improve genomic testing, and help researchers access the health data and technology they need to make new medical discoveries and create more effective, targeted medicines for everybody. Behind the Healthcare and Research outcomes, Genomics England delivers through designing, developing and operating complex healthcare software systems. We're on the cusp of big changes with the real prospect of genomics becoming the fabric of everyday healthcare through the lifetime – from birth to old age. Job Description We are seeking a Bioinformatics Engineer to help develop and scale knowledge platforms that underpin the NHS Whole Genome Sequencing (WGS) Genomic Medicine Service, including PanelApp and CellBase. These systems are key to clinical impact, by enabling management of the latest variant annotation data as well as curation, validation and delivery of gene–disease relationships into clinical pipelines across the NHS. You will work on big data production systems spanning Python-based services and Java-backed platforms , building APIs, data models, and pipelines that deliver high-quality, clinically relevant genomic knowledge at scale. In this role, you will collaborate closely with genomic data scientists, curators, engineers and pipeline teams to translate evolving clinical requirements into robust, testable software suitable for use in a regulated environment. You will take ownership of system design, implementation, and data integrity, ensuring that our platforms remain reliable, performant, and clinically trustworthy. You will work within an agile team to deliver and continuously improve production systems, contributing to engineering standards and shaping how we build. As a bioinformatics specialist in the team, you will guide design decisions and ensure that clinical and biological context is accurately reflected in the software. Everyday responsibilities include: Produce high-quality code for high throughput sequencing data analysis, genome analysis, workflows and interpretation. Interact with domain experts during the lifecycle of projects to ensure the scientific validity of software products. Contribute to discovery tasks during the initial phase of new developments and achieve understanding of early-stage decisions to inform final software design. Produce automated tests to validate existing and new code. Contribute to all testing and deployment stages up to the production environment. Write documentation to achieve an exhaustive log of decisions, designs, tests, results etc. that enable full traceability of processes. Be a proactive member of a squad, adopting agile practices and offering subject matter expertise. Ensure adherence to the various standards and accreditations required for both clinical laboratory practice and software delivery. Skills and experience for success: Core engineering Strong Python development skills, including writing production code, tests, and working with modern libraries and tooling. Experience designing and maintaining production systems such as APIs, data pipelines, or data‑backed services. Experience with collaborative development workflows (Git, code review, branching strategies) and CI/CD pipelines. Bioinformatics / data‑wrangling Experience working with genomic or other biological datasets and the associated standards and data models (for example gene/transcript models, variants, ontologies). Experience integrating and validating heterogeneous biological datasets (e.g. Ensembl, ClinVar, gnomAD, in silico predictors), including ingestion, harmonisation, and checking that downstream query results are complete and biologically or clinically meaningful. Ability to assess and ensure data quality, including identifying inconsistencies, designing checks to confirm completeness of data ingestion, and validating that system outputs are accurate and clinically appropriate. Desirable Programming experience with Java services. Experience with genomic variant annotation, gene–disease curation systems, or clinical knowledgebases. Qualifications MSc equivalent or higher in Software Engineering, Computer Science, Bioinformatics or equivalent experience. Additional Information Salary from: £56,000 Closing date for applications - Friday 22nd May Being an integral part of such a meaningful mission is extremely rewarding in itself, but in order to support our people, we’re continually improving our benefits package. We pride ourselves on investing in our people and supporting them to achieve their career goals, as well as offering a benefits package including: Generous Leave: 30 days’ holiday plus bank holidays, additional leave for long service, and the option to apply for up to 30 days of remote working abroad annually (approval required). Family-Friendly: Blended working arrangements, flexible working, enhanced maternity, paternity and shared parental leave benefits. Pension & Financial: Defined contribution pension (Genomics England double-matches up to 10%, however you can contribute more if you wish), Life Assurance (3x salary), and a Give As You Earn scheme. Learning & Development: Individual learning budgets, support for training and certifications, and reimbursement for one annual professional subscription (approval required). Recognition & Rewards: Employee recognition programme and referral scheme. Health & Wellbeing: Subsidised gym membership, a free Headspace account, and access to an Employee Assistance Programme, eye tests, flu jabs.Equal opportunities and our commitment to a diverse and inclusive workplace Genomics England is actively committed to providing and supporting an inclusive environment that promotes equity, diversity and inclusion best practice both within our community and in any other area where we have influence. We are proud of our diverse community where everyone can come to work and feel welcomed and treated with respect regardless of any disability, ethnicity, gender, gender identity, religion, sexual orientation, or social background. Genomics England’s policies of non-discrimination and equity and will be applied fairly to all people, regardless of age, disability, gender identity or reassignment, marital or civil partnership status, being pregnant or recently becoming a parent, race, religion or beliefs, sex or sexual orientation, length of service, whether full or part-time or employed under a permanent or a fixed-term contract or any other relevant factor. Genomics England does not tolerate any form of discrimination, harassment, victimisation or bullying at work. Such behaviour undermines our mission and core values and diminishes the dignity, respect and integrity of all parties. Our People policies outline our commitment to inclusivity. We aim to remove barriers in our recruitment processes and to be flexible with our interview processes. Should you require any adjustments that may help you to fully participate in the recruitment process, we encourage you to discuss this with us. Culture We have four key behaviours that represent what we would like Genomics England to feel like and the culture we want to encourage, in order for us to achieve our mission. These behaviours help us all work well together, deliver on our outcomes, celebrate our successes and share feedback with each other. You can read about these and other aspects of our culture here