Bioinformatician (12-Month Fixed-Term Contract)
1 day ago
Southampton
Bioinformatician (12-Month Fixed-Term Contract) Start date: February 2026 Location: Remote (UK-based) with occasional travel to Cambridge Company: Mid-sized biotech focused on cancer neoantigen evolution and next-generation immunotherapies Role Overview We are seeking a skilled Bioinformatician to join our Computational Biology team on a 12-month fixed-term contract. This role will focus on bringing key external genomics and immuno-oncology analysis pipelines in-house, ensuring they are robust, well-validated, and scalable for ongoing research programmes. The ideal candidate will bring deep experience in genomics, NGS data analysis, and computational workflows, along with strong proficiency in Python and bash/Linux. Candidates may come from either an academic or industry background, with: • PhD + 1–2 years of industry experience, or Key Responsibilities • Internalise and adapt existing external NGS/genomics pipelines, ensuring compatibility with internal infrastructure and data standards., • Develop, optimise, and validate workflows for DNA/RNA sequencing datasets, neoantigen prediction, and related immunogenomics analyses., • Collaborate with computational biologists, immunologists and wet-lab teams to define requirements and integrate pipelines into research operations., • Manage and QC large-scale sequencing datasets, ensuring accuracy, reproducibility, and traceability., • Contribute to pipeline documentation, version control, and best practices for computational reproducibility., • Provide bioinformatics support across project teams, including exploratory analyses, data visualisation, and troubleshooting., • Participate in sprint planning, technical reviews, and collaborative problem solving across cross-functional teams. Required Qualifications & Experience Academic Background • PhD in Bioinformatics, Computational Biology, Genomics, or related discipline, plus 1–2 years industry experience, OR, • Strong expertise in NGS data processing and analysis, such as alignment, variant calling, transcriptomics, or tumour immunogenomics., • Proficiency in Python for bioinformatics tool development and data manipulation., • Competency with bash/Linux environments, HPC/Cloud computing, and workflow automation., • Experience working with common bioinformatics tools (e.g., BWA, STAR, GATK, Nextflow/Snakemake, bedtools, samtools) is highly desirable., • Clear communicator able to translate computational outputs into actionable biological insights., • Collaborative mindset, comfortable working with cross-functional scientific teams., • Strong organisational skills and ability to meet milestones within a defined contract window., • Self-driven, solution-oriented, and comfortable adapting external methodologies to internal needs. Contract Details • Type: 12-month fixed-term contract, • Start: February 2026, • Location: Remote (UK), with occasional travel to Cambridge, • Time commitment: Full-time, • Reporting to: Principal Scientist – Comp Bio About the Company They are a science-led biotech focused on understanding the dynamics of cancer neoantigen evolution to drive the discovery and design of new, well-tolerated medicines. Their mission is to develop next-generation immunotherapies that reshape how the immune system recognises and responds to cancer. For a confidential discussion or more information get in touch with Eugene or a member of the the team @ KEMIO.