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About Us GeneEase discovers novel gene therapies for subclinical conditions overlooked by traditional medicine - genetic disorders affecting millions (alcohol intolerance, lactose intolerance, mild autoimmunity) where existing treatments are inadequate or nonexistent. We use computational biology to identify promising therapeutic targets, design gene therapy approaches (AAV, base editing, other modalities), validate mechanisms in silico, and partner with wet labs for experimental confirmation. We file patents and license IP to gene therapy companies for clinical development. Role Overview Lead computational gene therapy development: design therapeutics that can be manufactured, delivered, and clinically translated - not just theoretically promising targets. You'll evaluate targets, design vectors with practical constraints in mind (manufacturability, delivery, immunogenicity), validate in silico, and coordinate academic partnerships for experimental validation. 80% computational work, 20% wet lab coordination. You design experiments—partners execute them. Critical: You must understand what makes gene therapies succeed or fail in practice, not just in silico. Key Responsibilities Therapeutic Design with Translational Focus (40%) • Evaluate genetic targets (genetic clarity, deliverability, market size), • Design gene therapy approaches considering practical constraints:Manufacturability: AAV titer requirements, production scalability, purification, • Deliverability: Tissue accessibility, dose requirements, injection volumes, immunogenicity, • Regulatory feasibility: IND pathway, safety assessment, clinical endpoint definition, • Select modality (AAV, base editing, other), vector/delivery system, regulatory elements, • Protein modeling: Structure prediction (AlphaFold), molecular dynamics (GROMACS), enzyme kinetics, • Safety assessment: Biodistribution (PBPK), immunogenicity, off-target prediction, • Translational risk assessment: Therapeutic window, dose-response, durability predictions, • Identify labs with relevant capabilities (animal models, assays, AAV production), • Design experimental protocols considering practical feasibility (realistic timelines, achievable titers, appropriate controls), • Draft manuscripts, patent applications, pharma partner dossiers emphasizing clinical translatability Requirements Education: PhD in Computational Biology, Bioinformatics, Bioengineering, Systems Biology, or related fields (or MS with 3-5 years experience) Wet Lab Experience: 1-3 years hands-on experience (cloning, cell culture, transfection, assays). Gene therapy experience strongly preferred (AAV/lentivirus production, transduction, functional validation, titer quantification). Gene Therapy Technical: Vector design (AAV serotypes, promoter selection, cargo optimization, CRISPR guide RNAs), tools (Benchling, SnapGene) Gene Therapy Development Mindset: • Understand what makes vectors succeed vs. fail in practice (not just in silico), • Consider manufacturability, deliverability, and immunogenicity upfront Programming: Python (BioPython, pandas, PyTorch), R (Bioconductor), SQL, Git, Linux/HPC Nice-to-Haves • Gene therapy industry experience: Worked at gene therapy biotech in vector development, process development, or CMC roles, • IND-enabling study experience: Familiarity with GLP tox, biodistribution studies, dose escalation strategy, • AAV manufacturing knowledge: Production optimization, titer improvement, purification troubleshooting, • Academic/CRO partnership management: Protocol transfer, feasibility assessment, troubleshooting, • Regulatory awareness: IND/CTA filings, FDA feedback meetings, clinical endpoint selection Essential Traits • Autonomous problem-solver with mechanistic thinking, • Bridges computational predictions with biological reality, • Builds tools, not just uses them, • Communicates complex work to non-technical stakeholders Why Join Us • Shape the foundation of a product that bridges biology and computation., • Collaborate with a global, interdisciplinary team., • Flexible, remote-first engagement., • Opportunity to see your expertise directly influence product development. How to Apply Please submit your application at: We look forward to hearing from you!

About the role Our experimentation programme goes beyond CRO. We are an experienced Experimentation Team running a mature programme of testing within a large-scale Product Organisation, influencing millions of customers and delivering multi-million pound revenue and profit gains. As part of the broader Analytics function, the Experimentation Team plays a central role in shaping customer experiences across Tesco’s websites, apps, and digital platforms. We use data-driven experimentation to uncover insights, validate ideas, and drive continuous improvement across all touchpoints. This role sits within the Analytics & Optimisation team in Tesco Retail Media, a fast-growing area partnered closely with our Technology teams. The team supports a wide range of digital products—from online and app experiences to Marketplace and in-store digital entities. Our mission is to deliver innovative, customer-first propositions that also drive advertiser value. As Senior Optimisation Manager, you’ll lead experimentation efforts that improve user experience and media performance. You’ll collaborate with Product, UX, Engineering, and Analytics teams to identify opportunities, design robust tests, and communicate results that influence strategic decisions. You’ll also help evolve our optimisation practices, leading to the development of new strategies, frameworks, and processes that embed experimentation into the heart of our digital roadmap. You will be responsible for • Champion the customer across all projects and initiatives, • Lead end-to-end optimisation and experimentation, using Adobe Analytics and other insights to design, run, and analyse MV/A/B tests, • Drive recommendations to enhance Media performance and customer experience, • Collaborate with UX, Product, and cross-functional teams to build strong hypotheses and shape the product roadmap, • Partner with Analysts to present test results in a clear, engaging format with actionable recommendations, • Contribute and lead on experimentation strategy, roadmaps, and maturity by exploring new processes and expanding into new business areas, • Uphold Tesco’s Business Code of Conduct with integrity and due diligence, • Proven success in managing experimentation to drive commercial performance and customer insight, • Strong customer focus and passion for delivering excellent user experiences, • Experience in innovation and challenging the status quo, • Proficiency in testing platforms (e.g., Optimizely, Leanplum) and data analysis across multiple sources, • Advanced understanding of experimental design and statistics, • Effective communicator with strong presentation and stakeholder management skills, • Relevant experience or a degree (2:1 or higher) in a quantitative discipline We’re all about the little helps. That’s why we make sure our Tesco colleague benefits package takes care of you – both in and out of work. Click Here to find out more! • Annual bonus scheme of up to 20% of base salary, • Holiday starting at 25 days plus a personal day (plus Bank holidays), • Private medical insurance, • 26 weeks maternity and adoption leave (after 1 years’ service) at full pay, followed by 13 weeks of Statutory Maternity Pay or Statutory Adoption Pay, we also offer 6 weeks fully paid paternity leave You might know us as a supermarket, technology company or even for our award-winning mobile network. Truth is, we’re all of those things, and much more. Our colleagues work with one goal in mind, helping to make every day a little better for our customers, colleagues and communities all over the world. No two customers are the same, neither are our colleagues. At Tesco, we champion a balance that lets you thrive both in and out of work. Spend 60% of your week collaborating with colleagues at our office locations or local sites and the rest remotely. Whether you're just kicking off your career, juggling passions, or navigating big life events, we're here to support you. We always welcome a conversation about flexible working, so talk to us throughout your application about how we can support. We're proud to be an accredited Disability Confident Leader, where everyone’s welcome. That’s why we commit to providing a fully inclusive and accessible recruitment process. If you need support with your application, click here for more information. And if you're interested in joining our team but don't tick every box, don't let that hold you back from applying.

Strive have partnered with a leading vendor in the DevOps Infrastructure space and have been tasked with bringing in a London-based Enterprise Account Executive The Company: • Series B; $60m in total funding, • $15m ARR, • 4.5/5 rating on Glassdoor, • Strong focus on culture & organisational health, • 120% YoY Growth The Leadership: • Co-founders second venture - they also worked in the software team @ one of the world's largest stock exchanges, • Company CEO exited last venture for $600m, • Investor Leadership team invested in likes of GitLab, Twilio, Wiz etc.., • CRO has previously scaled towards 2x exits The Role • Enterprise Account Executive, • London based - hybrid, • Up to £240k OTE + equity, • Massive opportunity for long term progression Interview Process: · CV Deep dive · Hiring Manager Interview · Roleplay · Final call with CEO · Offer How to apply: Apply, send me an email, message me on LinkedIn or even just pick up the phone. If you don’t have an up-to-date CV, don’t worry that’s my job to help you with that. Just get in touch.

• Job Title: Senior CRA / Senior CRA II, • Location: Remote in UK, • Salary: £53,000 - £59,000 (DOE), • Additional Benefits: Car allowance (or company car) and bonus, • Sign-on Bonus: Potential sign-on bonus for qualified candidates, • Company: Global CRO RBW Consulting is thrilled to present an exciting opportunity on behalf of one of our esteemed clients. As one of the few rapidly growing Contract Research Organizations (CROs) for UK studies, our client is expanding their site management team with multiple hires this year. They are involved in a diverse range of studies, including cutting-edge research in advanced therapies such as CAR-T. Join a highly experienced team dedicated to excellence in clinical research. In this role, you will benefit from a supportive management team committed to your professional growth. They provide clear guidance on the skills needed for advancement and offer fluid career development opportunities across various departments. This company prioritizes quality over metrics and is currently generating significant excitement within their UK team. Key accountabilities • Autonomy of investigator sites with full responsibility for the successful management of sites through study life cycle (start-up to close-out);, • Conduct feasibility, pre-study, initiation, monitoring, and closeout visits for research sites, mainly phase 1 to 3 and within all available therapeutic areas;, • Prepare accordingly and attend investigator meetings, coordinating timely delivery and subsequent proper storage and accountability of clinical supplies and following-up of drug safety issues;, • Perform source document verification and case report form review;, • Perform regulatory document review;, • Conduct study drug inventory;, • Perform adverse event and serious adverse event reporting and follow-up; and, • Assess patient recruitment and retention. Qualifications • Bachelor of Science in health-related field (or equivalent), • Proven CRA experience; 3 years minimum Why Join? • Supportive Environment: Build strong relationships with a transparent management team focused on your development., • Innovative Approach: Work with a company that embraces a 360 monitoring approach and leverages AI to enhance efficiency and save time., • Results-Driven KPIs: Our client's key performance indicators are centered around tangible study outcomes, such as patient recruitment, visit reports, and resolving site issues., • Administrative Support: Dedicated admin staff to help with site management tasks, helping to maintain a balanced workload., • Training: Extensive training and buddy system in place., • Career Growth: promotion opportunities up to 4 times a year., • Therapy Areas: Access to mixed therapy areas, including advanced therapies like CAR-T. To apply Please click ‘apply’ or contact Joe Pearce for any further information About RBW Consulting RBW Consulting is a life sciences talent & strategic consultancy with purpose, delivered through what we call Human Intelligence. We help life sciences businesses change the world by giving them the people, insight & networks to innovate and scale. We are proud of our role in helping companies deliver better health and wellbeing outcomes for patients We give back by playing an active role in funding initiatives that change lives We’ve created a culture rooted in support, transparency and mutual commitment. We lead with our values from the inside; empowering and investing in our people is more important than short-term commercial gain. We are an equal opportunities Recruitment Business and Agency RBW Consulting is an equal opportunity workplace. We prioritize talent (both current and potential) over resumes, challenge the status quo, and value people as our most important asset. We do not discriminate on the basis of race, ethnicity, colour, sex, gender identity or expression, sexual orientation, religion, age, marital status, visible or invisible disability, medical condition, national origin, veteran status, or any other protected status. We strive to be a diverse workforce that is representative at all levels and are committed to building a team that represents a variety of backgrounds, perspectives, and skills.

Work Schedule Standard (Mon-Fri) Environmental Conditions Office At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future. Our global Clinical Operations colleagues within our PPD® clinical research services provide end-to-end support for clinical trials from study start up to monitoring through to study close out, across commercial and government contracts. Together, we help clients define and develop clinical programs, minimize delays, and execute high-quality, cost-efficient clinical studies. The PPD FSP Solution: PPD's Functional Service Provider division partner with and serve as an extension of our PPD team, supporting our customers key functions. We cover customer needs on every level, allowing them to do more with less, with an uncompromising commitment to quality. We deploy the same top-tier talent in ALL engagement models. Exceptionally trained, rigorously supported and technologically empowered to help customers manage capacity and set programs up for success. Joining within our PPD FSP functional area, allows you to join the renowned PPD CRO and still gain invaluable client dedicated experience. Discover Impactful Work: Take responsibility for coordinating the clinical monitoring activities, overseeing the CRO clinical /site management activities and co-monitoring the assigned international Ph 2/3 clinical studies in accordance with regulatory requirements, Good Clinical Practice (GCP) guidelines and SOPs to the most rigorous standards of quality, timely delivery and within budget, in order to assist in the delivery of Clinical Development objectives and achieve clinical excellence. Coordinate the achievement of assigned clinical study deliverables within a matrix organization under the leadership of the Clinical Project Managers (CPM). Be a client representative at site and build relationship with our investigators.. A day in the Life: • Ensure clinical activities coordination & oversight, • Ensure efficient and thorough study start-up by overseeing the Clinical team of the CROs and working closely with other relevant team members involved in the study set-up (DM, reg, CMC, etc); ensure feasibility report are exhaustive, Review site feasibility reports as per oversight plan , support the CPM in site selection, verify timely collection of essential study documents, such as regulatory and ethics committee documents for submission, and by controlling that all set up activities are performed prior to each site initiation, as per the oversight plan., • Support and ensure that all specific Client/CRO EDC system tasks under the clinical responsibility are completed and achieved according to the defined timelines without jeopardising the start of a trial. Support the Clinical CRO in the training of the CRAs on all study specific operational activities and participate in the organisation and preparation of the monitor and investigator meetings in collaboration with the other study team members (Corporate and/or affiliates, CROs as appropriate) Assist the CPM/ study team in the evaluation of detailed timelines and establishment of clinical studies milestones for assigned projects, ensuring that they are performed to the most rigorous standards of quality and timely delivery., • Prepare and/or assist in the production of all documents necessary to oversee the clinical activity implementation, monitoring and reporting in a professional, high quality and timely manner (such as monitoring oversight plan and clin, • Customize site Key Risk/Performance Indicator template and follow these KRIs/KPIs at frequency agreed in the oversight plan, • Validate the final clinical study documents (such as study manual, monitoring plan, prepared by the Clinical CRO., • Review all/a sample of site visit reports as per the Oversight Monitoring Plan, ensuring timely and appropriate follow up of issues raised by monitors (Corporate & affiliates and/or CROs as appropriate)., • If applicable, provide support and guidance to Internal CRAs (Client Corporate & Affiliates with provision of some supervision in specific cases)., • Coordinate and manage the CRO relationship, assisting CRO CRAs/CTLs when and where necessary. Collaboration with the CPM in the RFP process and participation to BID defense meeting, • If applicable to set up regular meeting with MSL (Medical Science Liaison) at LMA (Local Medical Affairs) who can support Clinical Operations at various steps (site qualification, site recruit, • Contribute to the efficient operation of the TA Group and to transversal project cross- TAs and other departments within client (e.g. systems implementation, change management initiatives, continuous improvement initiatives, • Ensure the monitoring oversight of different activities entrusted, • Co-monitor clinical studies according to the oversight plan, ensuring adequate contact with investigator sites, identifying and solving issues in study progress, verifying data in-house or by conducting co- monitoring visits, in collaboration with other study team members, and following up as required with CROs/CRAs/investigator., • Participate in the ongoing clinical study data reviews in collaboration with the other study team members., • Make appropriate and timely reporting in CTMS, with regular checks for quality and accuracy., • Ensure the agreed timelines for data collection (CRF/eCRF) and data clarifications/queries are met, sending information to data-management and monitoring CROs as appropriate., • Ensure that study samples/assessments flow as required per protocol is well coordinated between the various stakeholders (CROs/Vendors/client departments) from site to the central facility/specialized lab. Participate in TMF quality check review regularly to ensure adequate completion during the study course with a final thorough review at the end of the trial prior to study archiving, • Participate in the preparation and follow-up of any other study systems (such as IWRS/IMP forecasting/flow etc, as required, • Maintain and review key clinical documents required for Clinical Study Report (CSR), to ensure adequate quality (e.g. for CSR appendices publishing), • As appropriate, participate in the preparation of study documents and perform site visits prior to audits /inspection and assist in audit follow-up /findings resolution., • Be a client ambassador at site and create relationship with our Investigators, • Clinical activities (out of studies), • Contribute/participate on SOP update and review training material created by Process Training Management, • Contribute to the efficient operation of the TA Group and to transversal project cross- TAs and other departments within client (e.g. systems implementation, change management initiatives, continuous improvement initiatives, • EHS Responsibilities, • Comply with applicable EHS regulations and procedures., • Participate in the site's EHS performance by reporting risks, malfunctions or improvements, • Life science or medical graduate or other relevant qualifications., • Experience of minimum 1 year (ideally 2 years) of Lead CRA e.g. coordination of clinical activities/site management activities for the set up and running of international registrational studies (multiple sites/countries)., • Experience as a Field CRA monitor for at least 3 years (CROs or Pharma Industry), • Excellent Knowledge of Good Clinical Practice (GCP), ICH regulations., • Experience in preparing clinical study documentation for study set up, maintenance and closing, • Experience in managing and developing relationships with Contract Research Organizations (CROs). Global studies (multiple countries/sites) experience, • Good leadership skills, effective at mentoring and training, and capable of motivating and integrating teams, • Good planning and organizational skills to enable effective prioritization of workload, • Solid interpersonal and problem solving skills to enable working in a multicultural matrix organization, • Capable of working effectively in a changing environment with complex/ambiguous situations, • Familiarity with the practices, processes, and requirements of clinical monitoring, • Good judgment and decision making skills, • Effective oral and written communication skills, including English language proficiency, • Capable of evaluating workload against project budget and adjusting resources accordingly, • Sound financial acumen and knowledge of budgeting, forecasting and fiscal management, • Strong attention to detail, • Solid understanding of relevant regulations e.g. ICH/GCP, FDA guidelines, etc., • Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner., • Able to work upright and stationary for typical working hours., • Ability to use and learn standard office equipment and technology with proficiency., • Able to perform successfully under pressure while prioritizing and handling multiple projects or activities., • This telephone line is reserved solely for job seekers with disabilities requiring accessibility assistance or an accommodation in the job application process. Messages left for other purposes, such as not being able to get into the career website, following up on an application, or other non-disability related technical issues will not receive a response.

About ev.energy We are on a mission to decarbonise the grid by making EV charging greener, cheaper, and smarter. We are building the world’s largest Virtual Power Plant (VPP). By connecting to vehicles, chargers, we turn EVs into flexible grid assets that balance supply and demand, preventing blackouts and reducing reliance on fossil fuels. We are scaling rapidly across North America and Europe. We are moving fast, we are AI-first, and we are looking for builders who want to power the grid of the future. The Opportunity We are looking for a Senior Manager, Demand Generation who acts less like a "marketer" and more like a "Chief Revenue Officer" for their accounts. We have moved beyond the "lead volume" game. Our focus is on our Top 100 Accounts—large utilities, energy retailers, fleets. You will be the architect of our Account-Based Marketing (ABM) strategy, the "Ying" to our Content Manager’s "Yang," and the primary commercial partner to our Sales team. You will join a lean, high-ambition team where AI isn't a buzzword—it's how we outpace competitors. Core Responsibilities 1. ABM Strategy & Execution • From "Contacts" to "Accounts": Own the implementation of the ABM model. You will distinguish between:, • 1-to-1: Bespoke campaigns for our "Must-Win" utilities., • 1-to-Few: Cluster campaigns for specific segments (e.g., Energy Retailers in the Netherlands)., • CRM & Attribution (HubSpot): Own and manage HS for all demand generation activities, including campaign set-up, attribution models, reporting dashboards, lead scoring, and workflow optimisation. Ensure data accuracy across the funnel and deliver insights that strengthen marketing’s revenue contribution., • Campaign Orchestration: You don't just "run ads." You orchestrate the entire buyer journey—from the first LinkedIn impression or building nurture flows in HubSpot.to the personalized landing page, ensuring our message lands with the right stakeholders at the right time., • Field Marketing - Events with Purpose: You set the strategy for commercial events. You don't just book a booth; you build a business case. You manage the pre-event outreach with the Sales Reps, submit abstracts and secure speaking slots for our execs, and ensure we squeeze every drop of ROI from our trade association memberships., • Performance Measurement: Define KPIs for demand generation campaigns. Track, analyse, and report on the performance of campaigns, including ROI, deal quality, and pipeline impact, building and utilising HubSpot dashboards and attribution reporting. Provide insights and recommendations to optimise future campaigns. 2. Commercial Leadership & Account Squads • The "Account Squad" Lead: You will lead the bi-weekly Account Squad meetings (Sales + Demand Gen + Policy). Your role is to align these three pillars to unblock deals, accelerate pipeline velocity, and ensure every strategic account feels the weight of our brand., • Revenue Accountability: You are not measured by "MQLs." You are measured by influence, meetings booked, and deal progression. You must understand the complex commercial environment of large enterprise energy deals and how to navigate them., • Sales Enablement: Create practical marketing toolkits including messaging frameworks, sales enablement materials, demos and activation assets., • Sales Partnership: You will work lock-step with the Sales Director and the Sales Reps. If they have a target list, you have a campaign strategy. You provide the air cover, the intelligence, and the ammunition they need to close. 3. Marketing Operations & The AI Engine • AI-Native Builder: You will be our champion for the AI transition. You will use tools like Lusha, GammaAI, Lovable, and other LLMs to build assets, automate workflows, and create content at scale., • The Stack: You are the master of our tech stack. You excel at HubSpot and know how to integrate it with Webflow, GA4, and other tools to create a seamless data flow. You ensure we have a clean, actionable view of every account's engagement., • Website Ownership: You own the B2B website as a conversion engine. You will be hands-on with Webflow (or other AI builders), optimizing CRO, managing the roadmap, and liaising with Product/Design to ensure our digital face matches our enterprise ambition., • Budget & Reporting Precision: Manage the Demand Gen budget (Spendesk alignment) with a focus on high-impact, measurable spend and own our monthly reporting. The Profile: Who You Are • Commercial First: You speak the language of Sales. You understand deal cycles, buying committees, and the difference between a "user" and a "buyer.", • A "Doer-Strategist": You can present a quarterly ABM strategy to the VP in the morning and be fixing a HubSpot workflow or building a landing page in the afternoon., • AI-Native: You are excited by the speed of AI. You don't wait for permission (except from legal) to try a new tool that could save the team 10 hours a week., • Comfortable with Ambiguity: We are a startup in a complex, global, regulated industry. Things change fast. You don't need a map; you need a compass. You proactively come up with solutions when you see gaps., • Global Experience: You have experience marketing to B2B audiences in the UK/Europe and North America. Requirements • Experience: 5+ years in B2B Marketing, ideally in SaaS, Energy, Mobility, or a complex enterprise environment., • Hands-on experience driving demand in a B2B environment., • Key Skills:, • Deep expertise in HubSpot and Account-Based Marketing (ABM) is essential:, • Deep proficiency in HubSpot (CRM, reporting, campaigns, attribution), including hands-on experience building dashboards, running reports, structuring campaigns, managing data workflows, lead nurturing, scoring, and automated journeys., • Proven ability to manage and optimise paid media channels, including Google Ads and LinkedIn Campaign Manager., • Solid AEO/SEO knowledge and understanding of how organic and paid channels work together to drive demand., • Experience using tools such as Google Analytics, Tag Manager and Looker Studio to analyse, optimise and report on digital channels., • Strong understanding of CMS platforms, such as Webflow for managing and maintaining website content and conversion pathways., • Experience with data enrichment and hygiene tools, such as Lusha, to ensure CRM data quality and segmentation accuracy., • Understanding of the full customer journey and how we can capture/generate demand at various stages of the funnel, and help influence accounts through it (e.g.via retargeting, nurturing etc.)., • Ability to work well across teams, particularly with Sales., • Proven ability to analyse data, interpret trends, and use insights to improve campaign effectiveness and demand generation performance., • Mindset: High autonomy, commercial drive, and a passion for sustainability. Salary & Benefits The salary range for this role is: £70,300 - £86,100 (offer dependent on experience) Key benefits include: • EV allowance: 10% of your salary each month, towards purchasing or leasing an EV, • Equity, in the form of share options (granted as a % of your salary), • PMI and cash plan medical cover (via Bupa & Medicash), • Life assurance of 3x your salary, • Co-working access via WeWork (on-demand or subscription), • Annual 'Team Week' whole company offsite How we work The majority of people at ev.energy works on a fully remote basis, with a small number of roles based on-site in our testing sites. This role is fully remote. This means that most of our people work from home, but we're happy to provide co-working subscriptions if you'd like to spend time at a WeWork (or other co-working space close to you). We balance our remote set up by getting everyone together once a year for an offsite, as we know that spending time together IRL is super important. The assessment process For this role, you can expect the following assessment process: • Application review, • 1st stage interview with the hiring manager, • 2nd stage case study / task with some of the wider team, • 3rd stage interview with our of our senior leadership team, • Offer

Are you interested in working directly for a single sponsor while having the security and additional career opportunities that working for a global CRO can bring? Our team says it’s the best of both worlds…. ClinChoice is currently recruiting for a Director of Statistical programming to join our client’s team in a permanent position at UK—an exciting opportunity to lead impactful statistical strategy in a dynamic environment. ClinChoice is a global full-service CRO with a strong focus on quality, professional development, and supportive culture. As a client-facing role, we are looking for confident candidates with the ability to work independently whilst establishing a high-trust environment with the client’s counterparts. Key Responsibilities: * • Work alongside with Head of Statistical Programming to implement a comprehensive strategy to maximize efficiency in statistical analysis and reporting that encompasses vendor management, technological innovation, process automation, and adherence to industry standards, • Oversee a team of FSP programmers or vendor CROs to ensure timely, high-quality delivery of analysis datasets, tables, listings, and figures (TLFs) across multiple clinical trials, • Align programming strategies with compound/platform objectives and regulatory requirements (e.g., CDISC standards, FDA/EMA guidelines), • Drive the creation, review, and validation of SAS/R programs for clinical data analysis, including SDTM/ADaM datasets, efficacy/safety outputs, and integrated summaries, • Ensure adherence to SOPs, regulatory standards, and reproducibility, • Partner with Biostatistics, Clinical Development, Data Management, and Regulatory Affairs to shape clinical study designs, statistical analysis plans (SAPs), and submission strategies to meet project deliverables and timelines for statistical data analysis and reporting, • Represent programming in clinical study team and other key meetings (e.g., protocol reviews, submission readiness), • Lead the programming contribution to global regulatory submissions (e.g., NDAs, BLAs, MAAs), ensuring compliance with eCTD requirements, • Manage the production of submission-ready datasets, TLFs, and documentation (e.g., define.xml, reviewers’ guides), • Champion the adoption of advanced analytics, automation tools (e.g., SAS macros, Python), and new technologies (e.g., AI/ML) to enhance programming efficiency, • Develop standardized processes and mentor teams on emerging industry trends (e.g., RWE, decentralized trials), • Develop and establish efficient processes, innovative solutions, and standards to enhance the delivery of statistical analysis and reporting; t his may include optimizing work flow and infrastructure of the statistical programming environment, and also author relevant Standard Operating Procedures (SOP) to document and communicate these processes, • Bachelor’s degree in Statistics, Mathematics, Computer Science or related discipline, advanced degree preferred, • 15+ years (10+ years for advanced degree) experience in a pharmaceutical industry, CRO or another clinical research setting, with a focus on oncology, • Excellent knowledge of statistical programming in SAS including Base, macro, STAT, GRAPH, SQL, • Solid understanding of FDA, EMA, ICH, and global regulations and guidelines, • Solid understanding of industry standards applicable to clinical study data and reporting on clinical trials, including CDISC standards, • Solid understanding of the drug development process from early to late-stage development and submission, • Expertise in the requirements and technology to support electronic submissions, • Strong interpersonal skills in addition to exceptional written and oral communication skills commensurate with the need to work closely with CROs, investigators, consultants, and team members across functions, • Strong analytical, project management, and problem-solving skills #Director#Permanent

An exciting opportunity has come up for a Risk Officer to join a rapidly expanding, global hedge fund. The firm are highly prestigious and have established themselves as a leading name within the global equities space. London, their centre of European operations, is going through a strong period of expansion, creating multiple new roles within the business – the ‘Risk Officer’ hire is newly created. Joining a team of two, reporting directly to the CRO, the new hire will assist in overseeing risk management for EMEA. The role will cover all aspects of market risk, for all equities strategies, and it is highly quantitative / tech focused. The hire will sit with the front office team, working directly with market-leading PMs and traders daily and having a genuine involvement in trade ideas. The hire will be given significant autonomy and he/she will be responsible for overseeing the more junior member of the team. This is a fantastic opportunity to join an established, highly reputable hedge fund that is going through a very exciting growth phase. We are looking for an experienced Risk professional, ideally with 5-10 years of experience covering equities market risk at a buy-side firm, prop trading house or tier 1 bank. The role is highly quantitative – candidates should be proficient in Python or SQL and have experience in automation projects. My client pride themselves on paying some of the most attractive compensation packages in the industry. The successful candidate will receive a substantial uplift on his/her base salary and will be part of the firm’s front office bonus pool, meaning total comp will extremely lucrative.

About the role Our experimentation programme goes beyond CRO. We are an experienced Experimentation Team running a mature programme of testing within a large-scale Product Organisation, influencing millions of customers and delivering multi-million pound revenue and profit gains. As part of the broader Analytics function, the Experimentation Team plays a central role in shaping customer experiences across Tesco’s websites, apps, and digital platforms. We use data-driven experimentation to uncover insights, validate ideas, and drive continuous improvement across all touchpoints. This role sits within the Analytics & Optimisation team in Tesco Retail Media, a fast-growing area partnered closely with our Technology teams. The team supports a wide range of digital products—from online and app experiences to Marketplace and in-store digital entities. Our mission is to deliver innovative, customer-first propositions that also drive advertiser value. As Optimisation Manager, you’ll drive experimentation efforts that improve user experience and media performance. You’ll collaborate with Product, UX, Engineering, and Analytics teams to identify opportunities, design robust tests, and communicate results that influence strategic decisions. You’ll also help evolve our optimisation practices, contributing to the development of new strategies, frameworks, and processes that embed experimentation into the heart of our digital roadmap. You will be responsible for • Work with stakeholders to identify opportunities to improve customer experience and deliver business impact, • Manage and run testing activity from planning to implementation to analysis, • Build and test strong hypotheses through AB and MVT testing, • Analyse and share results in an engaging way with actionable recommendations, • Utilise Adobe Analytics and other insights tools to segment and evaluate test results, • Contribute towards the prioritisation process and help shape the product roadmap, • Proven success in managing experimentation to drive commercial performance and customer insight, • Strong customer focus and passion for delivering excellent user experiences, • Experience in innovation and challenging the status quo, • Proficiency in testing platforms (e.g., Optimizely, Leanplum) and data analysis across multiple sources, • Solid understanding of experimental design and statistics We’re all about the little helps. That’s why we make sure our Tesco colleague benefits package takes care of you – both in and out of work. Click Here to find out more! • Annual bonus scheme of up to 20% of base salary, • Holiday starting at 25 days plus a personal day (plus Bank holidays), • Private medical insurance, • 26 weeks maternity and adoption leave (after 1 years’ service) at full pay, followed by 13 weeks of Statutory Maternity Pay or Statutory Adoption Pay, we also offer 6 weeks fully paid paternity leave You might know us as a supermarket, technology company or even for our award-winning mobile network. Truth is, we’re all of those things, and much more. Our colleagues work with one goal in mind, helping to make every day a little better for our customers, colleagues and communities all over the world. No two customers are the same, neither are our colleagues. At Tesco, we champion a balance that lets you thrive both in and out of work. Spend 60% of your week collaborating with colleagues at our office locations or local sites and the rest remotely. Whether you're just kicking off your career, juggling passions, or navigating big life events, we're here to support you. We always welcome a conversation about flexible working, so talk to us throughout your application about how we can support. We're proud to be an accredited Disability Confident Leader, where everyone’s welcome. That’s why we commit to providing a fully inclusive and accessible recruitment process. If you need support with your application, click here for more information. And if you're interested in joining our team but don't tick every box, don't let that hold you back from applying.

• The VP Medicinal Chemistry will be accountable for developing a long-term vision and strategy for Chemistry and molecule discovery broadly, and will be expected to contribute to disease area strategies within these therapy areas. Working as part of a global leadership team the role holder will be accountable for developing the future of the Medicinal Chemistry capability, while building trusting relationships with senior scientific colleagues internally and externally to AstraZeneca. In addition to having a strong track record for successful delivery of clinical candidates, the role holder will be a leader in the creation and adoption of Artificial Intelligence methods within chemistry design and synthesis, with experience of the discovery of novel small molecule modalities including PROTACs and Molecular Glues. They will be a recognised leader in the field of Medicinal Chemistry with an extensive external network and scientific presence and will be expected to initiate and lead external collaborations and partnerships to create new capability and to deliver new science into the AstraZeneca portfolio., • The role will lead a department of Medicinal, Synthetic, Analytical and Computational chemists delivering deep technical and scientific expertise for the optimisation of novel small molecule leads and candidates for a diverse portfolio of projects within Cardiovascular, Renal, Metabolic, Respiratory and Immune Disease portfolio’s at AstraZeneca. The role holder will have a track record of the successful application of Artificial Intelligence and Machine Learning methods in molecule discovery, design and optimisation and will lead a high performing department with a passion for scientific delivery and innovation., • Key Accountabilities, • Delivery of a portfolio of small molecule, PROTAC, molecular glue and drug-conjugate projects to candidate selection, • The scientific and people leadership of a department of >120 scientists across AstraZenca sites in the disciplines of Medicinal, Synthetic, Analytical and Computational chemistry, • The management of >100 synthetic chemistry roles at CRO partners, together with the development of a future resourcing strategy for the department., • The identification and implementation of novel Medicinal, Synthetic and Computational Chemstry technologies, including the use of Artifical Intelligence methods, to advance the capability, • Represent department on cross organisational teams accountable for the delivery of the AstraZeneca portfolio; this will include membership of therapy area leadership teams and matrix governance committees, • Drive innovation, scientific excellence and external visibility of the Chemistry capability through internal scientific/technological development, external collaborations, publications and conference presentations, • Build and maintain a high performing team environment, with full engagement of staff and a commitment to continuous improvement., • PhD/Post-doc in Chemistry discipline with >20 years’ experience in a drug discovery environment, • Track record of leading large groups in highly matrixed science and technology based organisations and evidence of ability to shape groups to the needs of the business., • Track record of successfully delivering small molecule candidate drugs into the clinic, • A proven scientific track record of innovation and application of Artificial Intelligence methods in molecule discovery, • Proven ability to create new research strategies to drive organisational success, • Significant experience in the leadership of drug discovery projects, • Demonstrated ability to build and sustain collaborative relationships with scientific and leadership teams at local and remote research sites, and to initiate and successfully deliver value from external collaborations, • Experience in project management, change management and/or implementation of process optimization approaches, • Proven ability to recruit, retain and develop people to build a world-class organisation, • Experience of the development of informatics tools to enable integrated analysis of chemistry data

Are you interested in working directly for a single sponsor while having the security and additional career opportunities that working for a global CRO can bring? Our team says it’s the best of both worlds…. ClinChoice is searching for a Benefit Risk and Risk Management Lead Consultant for 12 months Contract with possibility of extension to join one of our clients. ClinChoice is a global full-service CRO with a strong focus on quality, professional development, and supportive culture. As a client-facing role, we are looking for confident candidates with the ability to work independently whilst establishing a high-trust environment with the client’s counterparts. Job Description Job Title: Benefit Risk and Risk Management Lead Employment Type: Contract About ClinChoice ClinChoice is a partner to the largest pharmaceutical, medical device, and consumer care innovators in the world. Established in 1995, we provide expertise in clinical operations, biometrics, regulatory affairs, pharmacovigilance, medical affairs, and toxicology to help our partners advance healthcare by accelerating clinical trials with data-driven insights, delivering the best strategies for product registration, and enhancing patient safety through real-world and clinical analysis. Our global delivery network has expanded to centers and satellite offices in the United States, Mexico, United Kingdom, Armenia, China, Japan, India, and the Philippines to help our customers maintain regulatory compliance locally and globally. We have forged future-defining partnerships with industry bodies and technology companies to develop cutting-edge solutions that deliver our expertise with quality and precision. Summary The Benefit Risk and Risk Management Lead is accountable for the global medical safety management of products and informs a robust understanding of the benefit-risk profile portfolio, assesses and reviews risk assessment/risk minimization activities, as well as additional pharmacovigilance activities, and if needed signal detection and evaluation to ensure products are safe for patients. Responsibilities: This leader will provide leadership and strategic insight and input into the following areas: • Lead, contribute to, and/or execute proactive safety surveillance and risk management activities, including product safety signal detection, evaluation, risk assessment, and risk minimization., • Contribute to benefit–risk assessments in partnership with other benefit–risk management functions., • Independently evaluate safety data from all sources, identify and analyze safety signals, and present medical assessments and benefit–risk evaluations to relevant committees and forums., • Develop independent action plans to address safety, risk, and benefit–risk issues, frequently coordinating cross-functionally to implement risk minimization strategies., • Review and approve safety documents, including those related to product benefit–risk profiles., • Ensure consistent safety and risk messaging for a product or product class across indications and business units., • Apply a strong understanding of aggregate safety data, signal detection methodologies, and benefit–risk assessment processes., • Conduct comprehensive safety data reviews, safety assessments, clinical safety signal identification, and risk identification and management., • Synthesize data to support informed benefit–risk decisions., • Demonstrate knowledge of global safety and regulatory issues relevant to clinical research and drug development., • Serve as the safety point of contact for Asset Teams and, when needed, chair appropriate Risk Management Committees., • Apply solid understanding of therapy mechanisms and drug-induced disease processes., • Lead cross-functional teams effectively, modeling commitment and enthusiasm in a matrixed environment with minimal oversight., • Exhibit strong scientific and medical expertise, including proficiency in interpreting medical literature., • Communicate clearly and effectively, both verbally and in writing., • Fulfill additional responsibilities as required by evolving project needs., • Medical Degree or equivalent, or a Healthcare professional, preferably with a postgraduate degree (Master’s, PhD or equivalent) in Pharmacy, Life Sciences, or a related discipline., • Minimum of 6 years of experience specifically in pharmacovigilance risk management., • Strong understanding of safety risk management principles and the relevant internal and external regulatory landscape, including applicable guidelines., • In-depth knowledge of pharmacovigilance regulations and requirements for the assigned geography., • Comprehensive understanding of the drug development process and post-marketing activities, with awareness of safety considerations throughout the product lifecycle., • Proven ability to influence and collaborate with internal and external stakeholders., • Ability to work independently while seeking guidance appropriately; recognizes and effectively leverages the expertise of colleagues to achieve team goals., • Demonstrated leadership, strong interpersonal skills, and experience working collaboratively in cross-functional environments., • High level of business ethics, integrity, and professionalism., • Strong communication skills with fluency in English., • Knowledge of good documentation practices, with strong attention to detail and accuracy., • Self-motivated, proactive, and able to work independently with a strong “can-do” attitude., • Global mindset, preferably with experience working in a multinational pharmaceutical organization.

As a pharmaceutical support industry leader, UBC is devoted to empowering health solutions for a better tomorrow. We take pride in improving patient outcomes and advancing healthcare. At UBC, we provide services to enhance the entire drug development process and commercialization lifecycle - from clinical trial support to real-world evidence generation. Embark on a rewarding career journey with UBC! Grow your career while making a meaningful impact on the world around you. UBC fosters a culture built on our Core Values of Respect, Accountability, Innovation, Quality, Integrity, and Collaboration. We believe in an inclusive workplace that fosters creativity. If you are seeking a career that will challenge, inspire, and reward you, join us at UBC! UBC are currently recruiting within our Project Management team, we are looking to recruit at CPM or a SR CPM Brief Description The EU PM is responsible for providing operational oversight of assigned UBC projects. The EU PM will have a leading role in planning, coordinating and completing project work. The EU PM will work closely with external clients/sponsors, internal project team members, vendors, and suppliers to ensure satisfactory delivery of contracted services and achievement of contracted milestones for assigned projects. The EU PM will ensure that projects are conducted in a timely manner to achieve project goals within defined budgets. Supervisory Responsibilities • Supervision of project team, • Supervise project management staff in execution of assigned studies, • Ensure that the PAds, PAs, APMs, PMs, project team members understand the client needs once a project is awarded, • Serve as a resource and mentor to the PA/APM in the execution of their daily activities, • Oversee the day-to-day management of European and/or multi-national global projects, • Manage project per the scope of work and within the contracted budget, • Oversee all aspects of project conduct from start-up through close-out, • Prepare project timelines and prepare or coordinate project development of deliverables, • Ensure project is conducted according to UBC and client SOPs, • Ensure conduct of project related training and record keeping, • Serve as the UBC primary contact with the sponsor for all project related items, • Coordinate project meetings including investigator meetings and client meetings, • Lead internal and external project meetings, • Ensure project budget is tracked against contract milestones, • Manage project budget and resource expenditures including invoicing, analyzing cost variances, out-of-scope management, and conducting revenue recognition., • Develop project plans to achieve contracted milestones (i.e. project plan, risk management plan, site management & monitoring plan, training plan, communication plan, etc.), • Monitor project progress against the established plans and ensure compliance with plans, • Supervise and provide direction to assigned project team members including PAs, APMs, Clinical Research Associates (CRAs), Clinical Site Specialists (CSS), Regulatory Associates (RA), • Focal point for resolving project team member questions, • Prepare and negotiate investigator/site/vendor budgets and assist with remediation of contract language, • Provide operational input and participate in the design and review of study protocols, case report forms (CRFs), study reports, and other functional documents and plans in collaboration with project team, • Coordinate development of patient/subject consent forms and site/patient materials, • Ensure Trial Master File (TMF/eTMF) is maintained and audit-ready on ongoing basis, • Monitor and ensure project team compliance with maintenance of Clinical Trial Management System (CTMS), • Completion of departmental oversight trackers for projects (e.g. functional resource forms, project review form, project execution checklist), • May be asked to perform Lead CRA or CRA duties on projects as needed, • Participate in internal UBC process improvement initiatives, • Prepare and participate in presentations to clients in defence of proposals, • Present project information at bid defences, client meetings and UBC internal project governance and review meetings, • Minimum a Bachelor’s degree or equivalent in a clinical, scientific, or related field, with an advanced degree desirable, or sufficient, relevant job experience, or another relevant education, • 2 to 3 years direct project management experience at a Contract Research Organisation (CRO) or 5 or more years of clinical trial experience, • Has proven working experience and understanding of working within clinical research, • Proficient in use of web based IT systems (e.g. CTMS or electronic Case Report Forms) and Microsoft (MS) Excel, MS PowerPoint, and MS Word, • Experience using project management software (e.g. MS Project), • Ability to effectively use automated systems and computerized applications, • Very good knowledge of regulatory requirements for research conduct (i.e. Good Clinical Practice, International Conference on Harmonization (ICH) guidelines, etc.), • Excellent working knowledge of clinical research/development, including medical and therapeutic areas, phases and medical terminology, • Knowledge of CRO/Pharmaceutical functional departments and responsibilities, • Good quantitative skills and working understanding of project budgets (solid financial acumen), • Excellent communication skills and ability to communicate effectively with all levels of an organization, • Excellent interpersonal, verbal and written communication skills, • Able to lead, motivate and coordinate teams, • Excellent planning and problem solving skills, • Able to delegate, effectively prioritizes own and workload of project team members, • Flexible and adaptable to changing situations, • Very good supervisory skills, • Very good presentation skills, • Excellent organisational and time management skills, • Proficient at multi-tasking with good attention to detail, • Has experience with leading, liaising and coordinating cross-functional project teams, • 10% travel

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Level 3 Qualified Personal Trainer - Thanet Westwood Cross - Thanet.

Start a career with one of the best beauty brands around?World famous beauty and cosmetics brand Avon is looking for full and part time representatives in the UK right now as business expands.See the TV Ad campaignThis is your chance to work with a premier international brand with 130 years of prove

The Senior CRO Manager oversees a team comprising a CRO Manager, two CRO Executives, and two Personalisation Managers, ensuring strategic alignment and operational excellence across all CRO initiatives. We'd love to hear from you! About the role The Senior CRO Manager at Hargreaves Lansdown (HL) is

Start a career with one of the best beauty brands around?World famous beauty and cosmetics brand Avon is looking for full and part time representatives in the UK right now as business expands.See the TV Ad campaignThis is your chance to work with a premier international brand with 130 years of prove

This is a fantastic opportunity to lead a team of surveyors and shape the way we deliver high-quality surveying services across our property portfolio.

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Were expanding our Asset teamand looking for a skilled and motivated Project Surveyorto help us deliver high-quality planned, cyclical, and service programmes of work.This is an exciting opportunity to be part of a dynamic and forward-thinking team thats committed to improving homes and communities.

Start a career with one of the best beauty brands around?World famous beauty and cosmetics brand Avon is looking for full and part time representatives in the UK right now as business expands.See the TV Ad campaignThis is your chance to work with a premier international brand with 130 years of prove

Were looking for a Senior CRO Manager to take the lead on conversion rate optimisation for a disruptive, market-leading brand in Financial Services.

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This role emphasizes driving growth through innovative acquisition strategies across product ecosystems.

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A global professional services firm is seeking an experienced Director to lead its Private Client team in Greater London.You will manage a diverse portfolio of clients with complex US and UK tax affairs, ensuring outstanding service delivery.Responsibilities include driving business growth, developi

Start a career with one of the best beauty brands around?World famous beauty and cosmetics brand Avon is looking for full and part time representatives in the UK right now as business expands.See the TV Ad campaignThis is your chance to work with a premier international brand with 130 years of prove

Candidates should have a minimum of 7 years of experience in business development within the CRO sector and a proven track record of securing multi-million-dollar contracts.

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A leading consulting firm is seeking a Chief Risk Officer to drive risk strategy, product innovation, and portfolio profitability across a growing network of MGAs.

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This role involves developing and executing a comprehensive product strategy, managing the product roadmap, and collaborating with cross-functional teams.

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Strong experience in government, the armed forces, or the Red Cross and Red Crescent Movement. At The British Red Cross, we pride ourselves on our diverse workforce, and ensuring we have an inclusive environment for all our staff and volunteers. As Head of Government Relations, you’ll play a vital

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A humanitarian organization based in London is seeking a Head of Government Relations to strengthen its role in humanitarian diplomacy.This position involves engaging with UK Government departments, leading strategic initiatives, and providing expert advice on humanitarian law and policies.Candidate

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Director - US/UK Cross Border Tax - London. You’ll play a key role in delivering outstanding client service across compliance and advisory matters, developing junior team members, and supporting business growth through effective portfolio management. Drive business development opportunities throug

Start a career with one of the best beauty brands around?World famous beauty and cosmetics brand Avon is looking for full and part time representatives in the UK right now as business expands.See the TV Ad campaignThis is your chance to work with a premier international brand with 130 years of prove

You’ll play a key role in delivering outstanding client service across compliance and advisory matters, developing junior team members, and supporting business growth through effective portfolio management. Drive business development opportunities through your network and collaboration with collea

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A leading global advisory firm is seeking a Vice-President for their Aerospace & Defence team within Investment Banking in Greater London.This role involves leading complex M&A and capital raising transactions, managing client relationships, and mentoring junior staff.Ideal candidates will have 6–

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A major NHS Trust in Bedfordshire is seeking a Lead Cardiology Specialist Nurse to oversee cardiology services across its two hospitals.

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A leading investment firm in the United Kingdom is seeking a Chief Risk Officer to drive its global risk management framework across various asset classes.

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