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We are seeking a highly skilled Senior Machine Learning Engineer to advance our personalised recommendation systems by developing efficient, low-latency solutions that serve millions of users globally. The successful candidate will collaborate closely with data scientists, engineers, and product managers to design intelligent content recommendation mechanisms and drive the ongoing advancement of our Machine Learning Platform. • Model Development: Design, train, and optimise machine learning models focused on user personalisation, encompassing recommendation engines, ranking algorithms, user segmentation, and content analysis., • Data Pipeline Engineering: Construct and maintain robust and scalable data pipelines for feature engineering and model training utilising both structured and unstructured large-scale datasets., • Production Deployment: Deploy and supervise ML models in production environments, ensuring high availability, optimal performance, and continued relevance., • Experimentation: Design and analysis of A/B tests and offline experiments to evaluate model efficacy and support continuous improvement., • Cross-Functional Collaboration: Engage with multidisciplinary teams to align machine learning initiatives with business objectives and user needs., • Research & Innovation: Evaluate emerging research in machine learning, deep learning, and personalisation for potential integration within existing systems., • Demonstrated expertise in the full lifecycle of machine learning, from model development, deployment and serving to monitoring and maintenance., • Strong proficiency in Python and knowledge of ML libraries/frameworks (e.g., TensorFlow, PyTorch)., • Experience using ML Training frameworks (e.g., TFX, Kubeflow Pipelines SDK) and Model Serving technologies (e.g., Tensorflow Serving, Triton, TorchServe)., • Experience with high-volume data processing and real-time streaming architectures., • Strong understanding of recommendation system design and personalisation algorithms., • Familiarity with Generative AI and its applications in production settings., • Exceptional communication and analytical problem-solving skills., • Proven successful experience in mentoring less experienced engineers to improve their technical skills. At the start of the day, you will join the team stand‑up and then choose a task to work on. Throughout the day, you’ll collaborate with team members and work on your current feature. You’ll also have opportunities for coffee breaks and team retrospectives. • Sky Q for the TV you love all in one place, • The magic of Sky Glass at an exclusive rate, • A generous pension package, • Private healthcare, • Discounted mobile and broadband, • A wide range of Sky VIP rewards and experiences We are a Disability Confident Employer, and welcome and encourage applications from all candidates. We will look to ensure a fair and consistent experience for all, and will make reasonable adjustments to support you where appropriate. We've embraced hybrid working and split our time between unique office spaces and the convenience of working from home. If your application is successful, we will ask you to complete a criminal record check and, depending on the nature of any convictions you may have, we might have to withdraw the offer. #J-18808-Ljbffr

Career CategoryMedical AffairsJob DescriptionIf you feel like you’re part of something bigger, it’s because you are. At Amgen our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of. Join us.SENIOR MEDICAL ADVISOR – CARDIOVASCULARLIVEWhat you will doIn this senior role, you will provide medical leadership across Amgen’s Cardiovascular portfolio, acting as the local medical expert and co-leading brand strategy with cross-functional partners.You will adapt global and regional strategy to local priorities, shape evidence generation and stakeholder engagement plans, and support high-quality execution across both inline and pipeline assets. Co-lead cross-functional brand strategy for designated products across the Cardiovascular portfolio. Provide medical leadership to ensure global and regional strategy is translated effectively into local priorities and plans. Engage external experts, professional organisations, and other key stakeholders to inform strategy and strengthen scientific partnership. Partner with marketing, value and access, and other internal stakeholders to support lifecycle planning and patient access initiatives. Contribute to UK and Ireland affiliate strategy and tactical planning in close collaboration with regional and global colleagues. Support evidence generation planning, including collaboration on company-sponsored studies and review of investigator-sponsored study proposals. Work with clinical operations to identify appropriate sites and investigators for future company-sponsored research. Lead and develop assigned team members through effective line management, including coaching, performance development, capability building, and oversight of resource planning. Deliver therapy area and product-specific medical training to internal stakeholders as required. Provide medical review and approval support for promotional and non-promotional materials in line with applicable standards and governance. Be part of our teamYou will be part of the UK and Ireland affiliate, working in a matrix environment with local Marketing and Value & Access teams, and regional and global partners.WINWhat we expect of youWe are all different, yet we all use our unique contributions to serve patients. What we seek in you as an experienced Pharmaceutical Physician, are these qualifications and skills: Degree educated. Medical affairs experience, gained within pharmaceutical or biotechnology company. Previous people management and/or leadership experience leading teams, projects, programmes, or resources is desirable but not essential. A genuine interest in people leadership is essential. Proven experience as a final ABPI signatory Demonstrated ability to work independently while building strong cross-functional partnerships, leveraging strategic thinking, commercial acumen, agility, and effective communication to adapt quickly and deliver business objectives in a dynamic environment. Product/therapeutic area knowledge within cardiovascular experience is preferred.THRIVEWhat you can expect of usAs we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.Vast opportunities to learn and move up and across our global organizationDiverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and actGenerous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefitsLOCATION: Ability to work flexibly from home with regular office work either from our Cambridge or Uxbridge next generation workspace.APPLY NOWObjects in your future are closer than they appear. Join us. careers.amgen.comEqual Opportunity StatementAmgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation..SummaryLocation: United Kingdom - Cambridge; United Kingdom - London; United Kingdom - UxbridgeType: Full time

Clinical If you feel like you’re part of something bigger, it’s because you are. At Amgen our shared mission, to serve patients, drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together, researching, manufacturing and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of. Join us. LIVE In this vital role you will lead the operational delivery of complex clinical programs, enabling execution with quality and speed at the forefront, bringing innovative medicines to patients who need them most. • Lead the operational planning and delivery of multiple clinical studies or programs, ensuring timelines, budget, quality, and strategy are met., • Proactively identify delivery risks and guide course-correction to keep studies on track., • Drive consistent, high-quality operational practices across all assigned studies and programs., • Line-manage and develop Study Delivery Leads, setting clear objectives and fostering high performance., • Oversee program-level issues, risks, and escalation, ensuring timely and effective resolution., • Partner cross-functionally and with local execution teams to align priorities, resources, and delivery plans., • Provide strategic input on study design, country selection, enrolment, diversity, and patient-centric approaches., • Manage program-level budgets, vendors, and forecasting while embedding lessons learned and continuous improvement., • Degree educated., • Experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation of resources. Your managerial experience may run concurrently with the required technical experience referenced above., • Previous experience in life sciences or medically related field, including biopharmaceutical clinical research experience obtained working on clinical trials at a biotech, pharmaceutical or CRO company., • Strong experience managing multiple teams / direct reports across multiple geographies., • Experience at or oversight of outside clinical research vendors (CRO’s, central labs, imaging vendors, etc.)., • Vast opportunities to learn and move up and across our global organization, • Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act, • Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits LOCATION: Ability to work flexibly from home with regular office work either from our Cambridge or Uxbridge next generation workspace. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation. #J-18808-Ljbffr

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”, a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it. What if your expertise could protect the integrity of clinical trials and the patients depending on them? At Bristol Myers Squibb, we're on a mission to transform patients’ lives through science. And behind every successful clinical trial is a team of brilliant people making sure the work is done right, done safely, and done with integrity. That's where you come in. We're looking for an Associate Director, Business Risk Management Lead (EU) to join our Trial Risk and Integrity Management (TRIM) team in Uxbridge, UK- a role where your instinct for risk, your passion for quality and your ability to influence people at every level will directly shape the future of clinical research. This isn't just a compliance role. It's a leadership platform. You won't be ticking boxes or writing reports that gather dust. You'll be the person who sees risks before they become problems and who builds the culture, the tools, and the confidence across teams to stay ahead of them. You'll work at the intersection of science, strategy, and people, touching global clinical programmes that matter. You’ll lead quality risk management end-to-end – identifying, assessing, and mitigating the risks that could threaten GCP compliance, clinical trial delivery and inspection readiness. Your work will directly protect patient safety and trial integrity on a global scale. You’ll turn data into decisions – using clinical data analytics and performance monitoring systems to spot trends, surface insights, and equip senior leaders with the evidence they need to act with confidence. You’ll influence without authority – partnering across R&D Quality, Global Drug Development Operations, Regional Clinical Compliance, and beyond. Your ability to connect, align, and inspire cross-functional teams will be your greatest tool. You’ll think globally, act locally – managing risk across processes, programmes, studies, regions, countries, suppliers, sites, and investigators. You’ll ensure the right risks reach the right people at the right time. You’ll build a culture people feel proud of – championing Quality Excellence and Inspection Readiness not as a mandate, but as a mindset. You'll coach colleagues, mentor new team members, and make risk management feel like a business enabler, not a burden. Real impact, real visibility.You'll sit within BMS's broader Risk Governance structure, giving you direct exposure to senior leadership and strategic decision-making. Your recommendations won't disappear into a committee - they'll shape how clinical operations run globally. A seat at the table for innovation.You'll lead risk-based innovation and education efforts. If you have ideas about how clinical risk management should evolve, this is a place where those ideas are welcomed and acted upon. Career growth baked in.With 8+ years of experience, you're ready to lead and this role stretches you further. You'll manage complex, multi-layered projects, drive continuous improvement initiatives, and develop the skills that open doors at the highest levels of clinical development. A team that actually collaborates.Cross-functional, global, matrixed - yes, it sounds complex, but it means you'll never work in a silo. You'll build relationships across geographies and disciplines, growing a professional network that lasts a career. The BMS difference.We're a company that genuinely believes in putting patients first. When you're doing this work here, every risk you mitigate, every process you improve, and every team you empower connects back to a patient who needs a therapy to work. You're likely a great fit if… • You have8+ years in clinical trial operations and/or GCP complianceand you're known as a go-to expert in risk management within your organisation., • You’re comfortable in complexity - navigating global matrices, managing multiple priorities, and keeping your cool when stakes are high., • You can walk into a room of mixed audiences - from scientists to senior executives - and communicate risk in a way that lands and drives action., • You lead through influence, not hierarchy, and you take genuine pride in helping others grow., • You’re data-fluent: you love a good trend, know how to visualise insights, and can translate numbers into narratives that move people., • You hold aBachelor's degree (life sciences preferred) and an advanced degree? Even better. Occasional travel required - because some of the best conversations still happen in person. Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working . BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplaceaccommodations/adjustmentsand ongoing support in their roles. Applicants can request a reasonable workplaceaccommodation/adjustment prior to accepting a job offer. If you require reasonableaccommodations/adjustmentsin completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. Bristol Myers Squibb is Disability Confident – Employer A UK Government scheme BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/ We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection . Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. If this posting is missing required information required by local law or incorrect, contact BMS at TAEnablement@bms.com with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account. R1598680 : Associate Director, Business Risk Lead (EU) #J-18808-Ljbffr

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The position offers a hybrid working arrangement, with 3 days based at your allocated office and 2 days working from home. Working hours are Monday to Friday, 9:00am–5:00pm, providing a consistent working week and a strong work-life balance. If you're looking to take your clinical experience in a

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The work style for this post is Frontline worker. A healthy environment supportive of work-life balance and caring responsibilities. This post is considered to be Regulated Work with children and/or protected adults as specified in the Protection of Vulnerable Groups (Scotland) (PVG) Act 2007.

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We welcome applications from all backgrounds and particularly from groups currently under-represented, including people with disabilities, those from minority ethnic communities or from socio-economically disadvantaged backgrounds. This post is considered Regulated Work with Vulnerable Children and/

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