Technical Writer
hace 7 días
High Point
Job DescriptionPay Rate Range: $20.00 - $36.00/hr. on W2Summary: • The Quality Control (QC) Investigation Writer is responsible for leading, authoring, and coordinating laboratory investigations within the Quality Control department in support of GMP-regulated pharmaceutical manufacturing operations. This role serves as a subject matter expert in the investigation process and is responsible for ensuring laboratory investigations are scientifically sound, thoroughly documented, compliant with regulatory requirements, and completed within established timelines., • The QC Investigation Writer partners closely with QC analysts, laboratory management, Quality Assurance, Microbiology, Manufacturing, and other cross-functional teams to investigate atypical laboratory events, identify root causes, assess product impact, and develop effective corrective and preventive actions. The position requires extensive experience with laboratory investigations including Out-of-Specification (OOS), Out-of-Trend (OOT), Environmental Monitoring (EM), and laboratory deviation investigations in an FDA-regulated GMP environment.Essential Duties and Responsibilities:, • Lead and author Quality Control laboratory investigations related to:, • Out-of-Specification (OOS) results, • Out-of-Trend (OOT) results, • Environmental Monitoring (EM) excursions, • Laboratory deviations, • Atypical laboratory events, • Invalid assay and microbiological test results, • Data integrity and documentation discrepancies, • Collect, review, and analyze laboratory data, test methods, chromatograms, worksheets, instrument records, environmental monitoring data, and supporting documentation to determine probable root cause and product impact., • Facilitate investigation meetings with laboratory personnel and cross-functional stakeholders to gather facts, evaluate evidence, and develop scientifically justified conclusions., • Perform and document root cause analyses using established investigation tools and methodologies., • Prepare clear, concise, and comprehensive investigation reports that meet internal procedures, FDA expectations, and current GMP requirements., • Develop scientifically justified impact assessments to determine potential effects on product quality, patient safety, regulatory compliance, and laboratory operations.Author and support associated quality records including:, • Deviations, • Corrective and Preventive Actions (CAPAs), • Change Controls, • Ensure investigations include appropriate corrective actions, preventive actions, effectiveness measures, and follow-up activities where required., • Review investigation records for completeness, technical accuracy, regulatory compliance, and adherence to established timelines., • Support Quality Assurance during investigation reviews and approvals., • Participate in regulatory inspections, internal audits, and customer audits by providing investigation documentation and supporting responses to investigator inquiries., • Identify recurring laboratory issues and recommend process improvements to reduce repeat events and improve laboratory compliance.Qualifications: Education: • Bachelor's degree in Chemistry, Microbiology, Biology, Biochemistry, Pharmaceutical Sciences, or a related scientific discipline required.Required Experience:, • Minimum 2 years of experience in a GMP-regulated pharmaceutical, biotechnology, or biologics environment., • Minimum 1 years of direct experience authoring and leading laboratory investigations within a Quality Control department (preferred)Demonstrated experience writing:, • OOS investigations, • OOT investigations, • Environmental Monitoring (EM) investigations, • Laboratory deviations, • CAPAs, • Change Controls, • Strong working knowledge of FDA regulations, cGMP requirements, and industry guidance related to laboratory investigations., • Experience conducting scientific evaluations and root cause analyses for laboratory events., • Experience reviewing analytical chemistry and/or microbiological testing data.Preferred Experience:, • Experience using electronic Quality Management Systems such as TrackWise., • Familiarity with FDA Guidance for Industry: Investigating Out-of-Specification (OOS) Test Results for Pharmaceutical Production and Current Good Manufacturing Practice regulations., • Knowledge, Skills, and Abilities:, • Advanced technical writing and documentation skills., • Strong understanding of laboratory operations, analytical testing, microbiological testing, and GMP documentation practices., • Ability to critically evaluate complex laboratory data and identify scientifically defensible conclusions., • Strong knowledge of investigation methodologies, root cause analysis tools, and quality risk management principles., • Ability to communicate effectively with laboratory personnel, Quality Assurance, Manufacturing, and senior leadership., • Excellent organizational skills with the ability to manage multiple investigations simultaneously., • Strong attention to detail and commitment to data integrity and regulatory compliance.Key Competencies:, • Technical Writing, • Laboratory Investigation Expertise, • Root Cause Analysis, • GMP Compliance, • FDA Regulatory Knowledge, • Quality Systems, • Analytical Problem Solving, • Cross-Functional Collaboration, • Risk Assessment, • Continuous Improvement