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Principal Computational Biologist (Systems Biologist) (Under the leadership of Alex Kalinka) Internally this is known as Principal Bioinformatician (Systems Biologist) £57,000 - £70,900 plus benefits (includes up to 12% pension contribution and income protection) Reports to: Group Leader - Quantitative Biology Directorate: Research & Innovation Contract: Permanent Hours: Full time 35 hours per week Location: Cambridge, Babraham Research Campus, Biomedical Campus (Limited flexibility 3-4 days per week on site) Closing date: 25 January 2026 23:55 This vacancy may close earlier if a high volume of applications is received or once a suitable candidate is found, therefore we strongly recommend that you apply early to avoid disappointment. Please let us know if there is anything about the recruitment process that you would like to discuss, in particular if there are any changes or adjustments that would make it easier for you to apply. Please contact or 020 3469 8400 as soon as possible. Visa sponsorship: Cancer Research UK can consider visa sponsorship for this vacancy. If this applies to you, please ensure that this is clearly marked on your application. Recruitment process: 1st stage interview via Microsoft Teams, 2nd stage will include a presentation followed by competency-based questions on-site Interview date: We will be booking in 1st stage interviews on an ongoing basis, 2nd stage in planned for 3 and 6 of February At Cancer Research UK, we exist to beat cancer. Cancer Research Horizons are looking to recruit a passionate scientific professional to set and drive our computational strategy for integrating cancer systems biology methodologies into our drug discovery pipeline to motivate key decisions arising in the target ID, target validation, and disease positioning spaces. About Cancer Research Horizons As the world's biggest medical research charity, we've helped bring eleven new cancer drugs to market. However, there is still an urgent need to bring more effective treatments to patients faster. We have recently developed a new approach to driving therapeutic innovation through the creation of Cancer Research Horizons (CRH). We have brought together Cancer Research UK's established drug discovery teams under one organisation and leadership team, combining our unique pipeline of cancer biology expertise and access to CRUK's world-class academic network, cutting edge technology platforms and clinical expertise to 1) bring new treatments to patients faster and 2) tackle the biggest challenges in discovering cancer drugs by seeking out more radical ideas and embracing risk in our bid to achieve success. Based at sites in Cambridge, the CRUK Scotland Institute in Glasgow, and Newcastle University, Cancer Research Horizons employs ~200 staff from both industrial and academic backgrounds This is a new role for the team and real chance to make a tangible impact from day one. Utilise your expertise to support CRH in taking take a bigger, more holistic view of cancer. Build robust evidence packages and leverage cutting-edge systems-level predictive modelling to uncover the molecular pathways driving cancer development. You will become an integral part of the Cancer Research Horizon Drug Discovery team helping to progress novel cancer targets towards patient benefit. Furthermore, we actively encourage our colleagues to celebrate our science, by attending conferences, presenting posters, giving talks at events and publishing papers. What will I be doing? Our new strategy sets out to bring deeper mechanistic understanding at the molecular and cellular level to all stages of projects, from idea to pre-clinical Candidate. Reporting directly to the Leader of our Quantitative Biology team, we are looking for an experienced computational biologist to develop a systems level approach to understanding cancer molecular networks to underpin predictive modelling of patient response that moves beyond single-gene biomarkers. In this role you will take a mechanistic, causative approach to understanding how patient somatic mutations drive the development of cancer and work closely with functional genomics scientists to test novel hypotheses. In this role you will: • Set and drive our computational strategy for integrating cancer systems biology approaches to support key decisions relating to target ID, target validation, and disease positioning., • Develop a patient-data focused biomarker strategy underpinned by a systems level understanding of cancer molecular pathways., • Analyse patient genomic data to uncover key somatic driver mutations and integrate this information with molecular pathways to build a mechanistic understanding of cancer development., • Provide deep expertise in computational biology and its role in oncology drug discovery., • Foster a culture of continuous improvement for our computational and analytical approaches., • Provide scientific and strategic leadership in computational biology across CRH., • Communicate effectively to influence multiple stakeholders and collaborate across projects and sites, including externally., • PhD in bioinformatics, data science, or equivalent, • Experience within a drug discovery environment (i.e pharma, biotech or academic institute), • A strategic thinker with proven scientific leadership, including through matrix management, • Experienced in the use and development of cancer systems level predictive modelling to uncover the molecular pathways underpinning cancer development, • Experience of working with oncology patient datasets and using them to test and generate novel hypotheses, • Experience of integrating multi-omics datasets (genomic, transcriptomic, proteomic, metabolomic) to infer molecular pathways involved in driving cancer, • Experience of using machine learning and AI tools to support a systems level understanding of cancer, • Programming experience with tools such as Python, • Experience adhering to good coding hygiene practices such as documentation, testing, and code review, • Excellent communication skills, ability to describe complex science in an engaging and inclusive manner., • Ability to build open and honest relationships and influence multiple stakeholders. Bold: Act with ambition, courage and determination Credible: Act with rigour and professionalism Human: Act to have a positive impact on people Together: Act inclusively and collaboratively We're looking for people who can believe in and embody these organisation values and can use them to drive forward progress against our mission to beat cancer. If you're interested in applying and excited about working with us but are unsure if you have the right skills and experience we'd still love to hear from you. What will I gain? We create a working environment that supports your wellbeing and provide a generous benefits package, a wide range of career and personal development opportunities and high-quality tools. Our policies and processes enable you to improve your work-life balance, take positive steps in your career and achieve your personal wellbeing goals. You can explore our benefits by visiting our careers web page. How do I apply? We operate an anonymised shortlisting process in our commitment to equality, diversity and inclusion. CVs are required for all applications; but we won't be able to view them until we invite you for an interview. Instead, we ask you to complete the work history section of the online application form for us to be able to assess you fairly and objectively. For more information on this career opportunity please visit our website or contact us. For more updates on our work and careers, follow us on: Linked In, Facebook, Instagram, X and YouTube.

Join Childbase Partnership and be part of something extraordinary Are you passionate about working with children and ready to build a meaningful career in early years? Our Early Years Apprenticeship offers the perfect opportunity to earn while you learn, gain a recognised qualification, and start a long-term career with one of the UKs leading childcare providers. The role Early Years Apprentice Youll work alongside experienced early years professionals, supporting babies and young children under the age of five in a safe, nurturing and inspiring learning environment. Location: West Cambridge Day Nursery, Cambridge,CB3 0FZ Contract: 37.5 hours per week, 52 weeks per year Working pattern: Varied shifts, Monday to Friday between 07:3018:30 Start date window: 12 March 17 April 2026 Salary: £7.57 per hour to start, rising to £10.00 per hour after six months in post Why join Childbase Partnership? Weve been delivering childcare excellence since 1989. Across our day nurseries, Head Office and Training Academy (EduBase), our ethos is simple: we all belong, we all matter, and we all contribute . We believe in careers, not jobs , and were proud to invest in the next generation of early years professionals. What youll receive Generous annual leave: 23 days paid leave per year (pro rata), rising to 28 days with length of service, plus paid bank holidays Outstanding childcare discount: 75% off nursery fees (or 40% grandparent discount) from day one Exclusive partner benefits: Long-service awards, qualification bonuses and retail discounts Wellbeing support: Free meals, mental health and occupational health support, flu jabs, eye care vouchers and a free will-writing service Career progression: A permanent role as a Qualified Nursery Practitioner on successful completion of your apprenticeship About us Employee-owned: Every colleague is a partner with a voice and when we do well, you receive an annual tax-free dividend Number one: Ranked top of the Nursery World league tables for Ofsted outcomes Community focused: Proud to have raised over £3.5 million for charity Environmentally responsible: All nurseries hold Green Flag awards and operate using 100% renewable energy Committed to learning: Our in-house academy, EduBase, is a trusted provider of high-quality early years training About you Youll thrive in this role if you are: Passionate about working with children: Youre interested in child development and excited to build a long-term career in early years Eager to learn: You enjoy hands-on learning and are motivated to develop skills in planning and delivering engaging activities linked to the early years curriculum Nurturing and safety-focused: You ensure every child feels safe, valued and happy, following policies, procedures and guidance from your management team and Trainer/Assessor Organised and self-motivated: You can manage your time effectively, making good use of off-the-job learning time and completing coursework to deadlines A team player: You communicate confidently and enjoy building positive relationships with children, parents and colleagues What does our apprenticeship offer you? A blend of practical experience and theory: Youll be based in the nursery, with regular visits from a Trainer/Assessor and group training sessions (every 68 weeks) at our academy in Newport Pagnell A recognised qualification: Study towards a Level 2 Early Years Practitioner or Level 3 Early Years Educator qualification, determined through an online initial assessment Functional Skills support: If required, youll complete English and/or maths Functional Skills qualifications in line with government and EYFS requirements Paediatric First Aid: Training delivered at our academy, with certification valid for three years Eligibility criteria To be considered, you must: Have the Right to Work in the UK and a National Insurance number Ideally hold photographic ID (passport or driving licence full or provisional) Have access to a laptop or PC for online assessments and coursework Have been resident in the UK for at least the last three years Be able to travel to group training sessions in Newport Pagnell (MK16 8NJ) travel costs will be covered Inclusion & next steps Were proud to be an inclusive employer and welcome applications from all backgrounds. Applicants must be 16+ , in line with government apprenticeship rules. Were committed to FREDIE fairness, respect, equality, diversity, inclusion and engagement and will consider any reasonable adjustments. If you meet the essential criteria, your application will be automatically shortlisted for review by our Recruitment Team. Applicants must live within a commutable distance of the nursery. Visa sponsorship is not available. Safer recruitment checks apply, including an Enhanced DBS check . We reserve the right to close this vacancy early. TPBN1_UKTJ

Release Engineer page is loaded## Release Engineerlocations: Cambridge Officetime type: Full timeposted on: Posted Todayjob requisition id: JR100813Darktrace is a global leader in AI for cybersecurity that keeps organizations ahead of the changing threat landscape every day. Job Descript

Keywords: Systems Engineering, Software Engineering, Hardware Engineering, Internet of Things (IoT), Embedded Systems, Firmware Development, System Integration, Network Protocols, Cyber-Physical Systems, Real-time Operating Systems (RTOS), Sensor Networks, Microcontroller/Microprocessor Systems, Clo

A technology consulting firm in Greater London is seeking an individual to develop and enhance identity and authentication solutions. The role involves managing Microsoft Entra ID services, enhancing Active Directory environments, and troubleshooting IAM issues. Candidates should possess expertise i

This role offers a mix of autonomy, influence, and hands-on technical engagement — ideal for someone looking to step into a strategic role without losing touch with the detail. A solid grasp of EU MDR (and legacy MDD), FDA requirements, and international submission processes. Confidence working ac

The successful candidate will manage tasks across multiple content management systems, collaborate with teams to optimize content distribution, and identify improvements to operations. A global entertainment company in London is seeking a YouTube Content ID Manager. This full-time role requires 3+ y

Hybrid (3 days office, 2 days home). Hybrid working with three days per week onsite in Oxfordshire and two days remote. Apply now with your CV or get in touch for a confidential conversation.

The ideal candidate will possess strong project management skills and a passion for ID&B initiatives. A leading online convenience marketplace is seeking a Senior Specialist to drive strategic advancements within their Inclusion, Diversity, and Belonging (ID&B) strategy.

Do you enjoy building experimental systems that bridge physical and digital engineering?. This is a rare opportunity to join a forward-thinking engineering company where your ideas and technical skills will help shape the future of complex hardware testing. This role sits within their experimental t

A healthcare provider in London is seeking a Consultant Forensic Intellectual Disability Psychiatrist to lead a multidisciplinary team at the Turner LDA ward.

You’ll need a strong background in engineering, computer science, or physics, experience in computer vision or robotics, and the confidence to take ownership of your own projects in a fast-paced environment. If you’re ready to lead real innovation in a company where ideas turn into products quic

A leading healthcare provider is seeking an experienced Infectious Diseases/Microbiology Consultant for a locum role in the Midlands. Candidates should have relevant outpatient therapy experience and at least six months in NHS or private hospitals. Accommodation options are available, and there is a

You are a confident full stack engineer who enjoys understanding how systems fit together and takes pride in the quality of what you build. Hybrid working with a collaborative Oxfordshire based team. Apply now or get in touch for a confidential chat.

Ideal candidates must hold relevant medical qualifications, exhibit strong leadership skills, and possess a commitment to continuous professional development. The role involves medical leadership in a multidisciplinary team and the delivery of care to patients with intellectual disabilities.

You’ll get hands-on with a wide range of modern technologies, including:. Fully remote (UK-based), or flexible hybrid if preferred. We welcome applicants of all backgrounds, identities, and lived experiences.

The ideal candidate will have strong project management skills, narrative building expertise, and a collaborative spirit. This 12-month fixed-term contract provides an opportunity to influence ID&B practices globally within a dynamic environment that values diversity and inclusion.

The ideal candidate will have a desire to become a specialist in robotics and embedded systems. A desire to pick up skills for data mining and uncovering hidden insights. Strong problem-solving skills and the ability to identify anomalies.

Ideal candidates should possess a primary medical degree, GMC registration, and experience with intellectual disabilities. A leading mental health service in London is seeking a Consultant Forensic Intellectual Disability Psychiatrist to join their innovative multidisciplinary team. Responsibilities

They are now seeking a Test Manager to lead software testing and validation with precision and confidence. Didcot, England, United Kingdom 1 week ago. Collaborate with multidisciplinary teams working across cloud software, embedded systems and smart devices.

This opportunity could be ideal if you are:. Looking for temporary work to build your skills and confidence in a business environment.

The Senior Specialist, Global Inclusion, Diversity and Belonging will play a pivotal role in driving strategic advancements within our ID&B strategy. The role takes ownership of critical initiatives, including establishing robust governance for our Employee Resource Group (ERG) ecosystem and craftin

The incumbent will lead a team, providing legal support on crucial legislative reforms and guiding the organization's strategic priorities. Ideal candidates will have substantial expertise in data protection law, strong leadership abilities, and experience engaging with senior stakeholders. The role

The role involves designing and implementing global identity solutions across on-premises and cloud environments, requiring expertise in Active Directory and Microsoft Entra ID. A global financial services group in London is seeking an experienced Microsoft Active Directory / Entra ID Engineer for a

In a data-driven world, we provide advice, guidance, and support to organisations enabling compliance with their obligations, as well as protecting individuals and their personal data. Provide the Senior Information Risk Owner (SIRO) with assurance that information assets are appropriately managed i

Ideal candidates will have over 3 years of relevant experience, a deep understanding of YouTube's Content ID systems, and strong data analysis skills. A global entertainment company is seeking a YouTube Content ID Manager (Music) to manage its vast kids’ content portfolio. This role involves overs

This role is extremely varied and your daily duties will consist of:.Being responsible for the social media marketing & management.Coordinating events, public engagement & external relations.Purchasing orders & invoices, and monitoring payments.Being responsible for the insights, systems, coordinati

Thank you for considering the YouTube Content ID Manager (Music) role with Moonbug Entertainment, an award-winning global entertainment company inspiring kids everywhere to laugh, learn and grow. Moonbug believes every child should have access to our entertaining and enriching content, which is why

A leading UK university is offering a PhD position focusing on the impact of generative AI in facial identification. Candidates should have a strong academic record in relevant fields and are encouraged to apply, especially if they have coding or machine learning experience. This role provides the u

Thank you for considering the YouTube Content ID Manager (Music) role with Moonbug Entertainment, an award-winning global entertainment company inspiring kids everywhere to laugh, learn and grow. This is a mid-level, individual contributor role for a hands-on specialist who is obsessed with process,

Ideal experience and skills include (not all are mandatory):. Software Engineer (Python/Golang/DevOps) - Up to £60,000 - ID37652. This range is provided by Humand Talent.

A global technology group is seeking an experienced Security Engineer with expertise in Microsoft Identity and Access Management (IdAM), particularly Entra ID and Active Directory. Candidates should possess strong consultancy skills and a background in security frameworks.

Govern identity lifecycle management, PIM, and Identity Protection. This is a great opportunity to be part of a technically advanced team driving secure external collaboration and identity governance using. Azure identity and security implementation within one of the UK’s most important financial

Collaborating with a skilled, multidisciplinary team in a hybrid setup. We’re proud to support equal opportunity for all, and welcome applicants regardless of age, disability, gender identity, race, religion or belief, sex, sexual orientation, or background. ML Systems Engineer - Up to £75k ID424

The ideal candidate has over 3 years of hands-on experience with YouTube CMS, demonstrating strong analytical skills and a detail-oriented mindset. A global entertainment company is seeking a YouTube Content ID Manager (Music) to join their Platform Operations team in London. This role involves mana

Provide consultation on people matters including talent management, organizational design, compensation, and employee development. Deliver guidance on company policies, local employment practices, and HR programs. Audible is the leading producer and provider of audio storytelling.

Senior Software Architect (E-commerce) - to £120k - Relocate out the city - ID44371. This role is ideal for a current. Hybrid working, supportive leadership, and a down‑to‑earth company culture.

A very fast-paced and busy EA role with varied day-to-day duties including:.Communications and inbox management.Preparation of concise briefings ahead of meetings.Managing board, governance, and stakeholder coordination across the organisation.Supporting with personal travel arrangements and family-

The ideal candidate will possess strong project management skills, the ability to create compelling narratives in slide decks, and demonstrate a strong sense of ownership, initiative as a self‑starter, and a hard‑working, collaborative approach. The Senior Specialist, Global ID&B will play a piv

Design and implement global identity solutions for hybrid environments (on-premises and cloud). Subject-matter expert knowledge of Microsoft Entra ID and related cloud identity services. We are seeking an experienced Microsoft Active Directory / Entra ID Engineer to join our Core Infrastructure IAM

Subject-matter expert knowledge of Microsoft Entra ID and related cloud identity services. The successful candidate will work within the Core Infrastructure IAM team and must demonstrate proven expertise in identity and security solution implementation. Design and implement global identity solutions

Thank you for considering the YouTube Content ID Manager (Music) role with Moonbug Entertainment, an award-winning global entertainment company inspiring kids everywhere to laugh, learn and grow. Moonbug believes every child should have access to our entertaining and enriching content, which is why

Ideal candidates have strong technical expertise in Active Directory, proven leadership skills, and are adept in automation and security compliance. This role requires on-site presence for three days a week and offers substantial opportunity for impact across identity and access operations. A techno

Be part of a multidisciplinary environment where you will work alongside teams involved in electronics, software, and manufacturing. This opportunity is for a Mechatronics Product Designer - CAD Design - to £80k - ID42613. This range is provided by Humand Talent.

Lead Software Engineer - 95% Remote - £85k - ID41216. This range is provided by Humand Talent. Are you a technical leader ready to guide a high-performing engineering team?.