Trabajos scientific en MacclesfieldCrear alertas

Providing analytical and statistical methodological insight to studies using secondary sources of real world data. You will work collaboratively with an enthusiastic and friendly team, leading various research projects from conception and study design through to reporting and publication. Adelphi Account Management and Growth Account Management Providing analytical and statistical methodological insight to studies using secondary sources of real world data. You will work collaboratively with an enthusiastic and friendly team, leading various research projects from conception and study design through to reporting and publication. Ø Drive methodological expertise within the team: o Advising study teams and clients on the suitability of proposed methods to address the research questions and recommending optimal approaches. • Critically reviewing and providing feedback on study protocols (e.g. study design and statistical methods) for review by clients and other review committees., • Critically reviewing and providing feedback of robust, transparent and coherent Statistical Analysis Plans (SAPs), incorporating comprehensive operational definitions and/or code lists, statistical methods, objective‑specific analyses and table shells, for implementation by others with limited scope for interpretation., • Critically reviewing study findings, and supporting project teams in the interpretation of complex analyses., • Translate client evidence needs into tangible analytical approaches and study design options., • As a biostatistics technical leader within the team, contribute innovative epidemiological and statistical methods for addressing client evidence needs. Ø Involvement in client delivery o To represent and communicate to clients the biostatistics expertise within the team. Ø Analysis and reporting of results: o Work with Statistical Programmers (SPs) on completing statistically complex analyses, including contributing to programming work when necessary • Supporting the interpretation and completion of the final research report and the presentation of the study results., • Authorship of publications, including development and/or critical review of abstracts/posters for presentation at scientific congresses or manuscripts for submission to peer‑reviewed journals. Ø Development of a team and co‑ordination of resources: o Help team members (both SPs and non‑SPs) to learn and develop new skills in epidemiology and biostatistics. • Motivating individuals within the SP team i.e. play an active role in developing an environment of continued learning., • Seek and advise new training opportunities to develop junior team members on the analysis of secondary data., • Inform the development of, and provide final sign‑off for, training and development materials., • Demonstrate agility and flexibility to support teams and clients in the face of competing priorities., • Line Management responsibilities. Adelphi Real World is a global consultancy in healthcare. We collect and interrogate real world data to aid the pharmaceutical industry in understanding the management and treatment of specific diseases. This understanding informs the successful development of pipeline assets and the positioning of products in market. Real world data can also be used to leverage Health Outcomes / Economic argumentation through statistically validated publications. Omnicom’s policy requires employees to work in the office for a minimum of three days a week, unless additional in‑office days are directed by their agency or manager. Our objective is to increase this requirement over time, and many of our agencies as well as Omnicom’s corporate group already require five days of in‑office attendance. Omnicom is committed to hiring and developing exceptional talent. We agree that talent is uniquely distributed, and we’re focused on developing inclusive teams that can bring the best solutions to everything we do. We strongly believe that celebrating what makes us different makes us better together. Join us—we look forward to getting to know you. We will process your personal data in accordance with our Recruitment Privacy Notice. Link to Recruitment Privacy Notice: privacy-notice/ #J-18808-Ljbffr

The Business Development Manager is a pivotal role for Jodrell Bank Centre for Engagement (JBCE), responsible for driving and maximising earned income across the centre from venue hire, groups, filming and other revenue generating initiatives at a unique, UNESCO world heritage site. The role is responsible for leading and driving all sales activity, together with the development and delivery of the centre’s business strategy which proactively generates new business and income across corporate meetings, events and private dining, together with weddings, group bookings and filming opportunities. Commercial activity will be successfully converted, planned and delivered through building strong relationships with corporate clients, agencies, private bookers and key partners, together with colleagues across JBCE. In this role, you will: Curate a "unique" commercial offer & experience:develop premium packages and offers which reflect Jodrell’s location and unique facilities for corporate and group bookings. Lead an inspired team:Motivate and empower our Events Coordinator and team of Casual Event Assistants to deliver professional client liaison and exceptional customer service when attending site for their booking/event. Commercial focus: Have a keen focus on commercial success, driving revenue and maximising profitability, whilst being mindful of other activity across a busy visitor and educational site. Partner for success:Collaborate with the Head of Marketing & Communications, together with the Catering & Hospitality Manager to help plan marketing and sales initiatives to showcase the facilities and catering across Jodrell Bank for bookings and events. Contribute to our strategic vision:Set and track key performance indicators for commercial business,check costs,analyse budgets,and contribute to the annual business plans for Venue Hire, group bookings and other income streams. Jodrell Bank is a vibrant centre for scientific discovery, education and inspiration. You will join a passionate team and play a key role in shaping an outstanding visitor experience. Our Values Jodrell Bank Centre for Engagement (JBCE) is a Cultural Institution of the University of Manchester. We value: Inclusivity: we support participation for diverse audiences, communities and staff, seeking to connect people with Jodrell Bank and with each other. Furthermore, we strive to create an inclusive culture by recognising each other’s differences and strengths. Integrity: we care deeply about the impact of our work, and we hold ourselves to high standards. We value honesty and integrity, ensuring that our practices are always responsible, ethical and sustainable. Empowerment: we empower our audiences, communities, our staff and our volunteers to enable confidence. Support: Our success rests on the achievements of others, and in turn we aim to provide the tools and the support needed to inspire others. All colleagues are expected to share this vision and help create a rewarding and fulfilling working environment. What you will get in return: • Fantastic market leading Pension scheme, • Excellent employee health and wellbeing services including an Employee Assistance Programme, • Exceptional starting annual leave entitlement, plus bank holidays, • Additional paid closure over the Christmas period, • Local and national discounts at a range of major retailers As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit. Our University is positive about flexible working – you can find out more here Hybrid working arrangements may be considered. Please be aware that due to the number of applications we unfortunately may not able to provide individual feedback on your application. Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies. Enquiries about the vacancy, shortlisting and interviews: Name: Adam Woof Email: General enquiries: Email: Technical support: support/home This vacancy will close for applications at midnight on the closing date. Please see the link below for the Further Particulars document which contains the person specification criteria. #J-18808-Ljbffr

Unfortunately, we are unable to offer visa sponsorship for this role. This is a full time, permanent position, working a flexible 36.5 hour week, Monday - Friday. We are recruiting for an enthusiastic and innovative Analytical Scientist for Eurofins at a client facility, a world-class pharmaceutical company based in Macclesfield. We have an opportunity for experienced Analytical Scientists with experience in drug substance development in the pharmaceutical industry. • You will act as the key point of contact for Eurofins clients, providing analytical testing expertise and subject matter knowledge across designated product areas., • You will use your analytical chemistry expertise to support global laboratories and external partners, ensuring the robustness, performance and compliance of analytical methods for drug substances., • You will coordinate analytical activities and support major change programmes and market access projects, working closely with cross-functional teams including Quality, Regulatory Affairs, Manufacturing and External Sourcing., • You will lead the transfer of commercial analytical methods to multiple laboratory locations, ensuring successful implementation and consistent operational standards., • You will collaborate with internal and external stakeholders to resolve technical challenges, drive continuous improvement and maintain regulatory compliance across analytical operations., • You will lead and develop a small team of analytical scientists, providing technical guidance, mentoring and support while contributing to international projects that may involve travel., • You will hold a degree, Master's degree or PhD in Chemistry, Pharmacy, Pharmaceutical Sciences or a related scientific discipline, with relevant post-graduate industry experience., • You will have proven experience in pharmaceutical analysis within a development laboratory environment, including leadership experience and the ability to guide technical teams., • You will have a strong understanding of chemical substance lifecycle management, from late-stage development through to commercial manufacture and ongoing product support., • You will have excellent project management, stakeholder engagement and influencing skills, with the ability to communicate effectively and collaborate across multiple functions., • You will have experience in data analysis and statistical interpretation, alongside extensive knowledge of analytical method development, optimisation, validation and transfer for release and stability testing., • You will have a thorough understanding of analytical techniques, root cause investigation, change assessment, SHE and cGMP requirements, with exposure to wider CMC disciplines, Quality, Regulatory Affairs and Manufacturing considered advantageous., • At Eurofins we are growing, innovating and always learning. We celebrate the achievements of our employees through annual long service awards, recognise our colleagues special life events, and we are committed to charitable causes through global fundraising activities., • Reward and Recognition Scheme recognizing great work across our teams., • Holiday entitlement increases with service., • Option to opt into Health Cash Plan to help look after everyday health and wellbeing (claims for routine healthcare expenses)., • Life Assurance from day one (four times annual salary)., • Automatic enrolment into Company Pension Plan after three months (flexible to opt out)., • Access to Employee Assistance Programme (24/7 confidential support)., • Volunteering days program to support community involvement during working hours., • Free on-site car parking., • Opportunity to explore worldwide opportunities and access to Perkbox for savings and benefits. Our people are the backbone of what we do, so it's important we find the right individuals to join us. As a potential new recruit you may be invited to meet the team in an assessment centre or staged interview process depending on the role and its requirements. This will give you the opportunity to see what working for Eurofins is like and to showcase your key skills and strengths. #J-18808-Ljbffr

We are seeking a Scientist (LBA) to perform bioanalytical and Ligand Binding Assay (LBA) activities in a regulated CRO environment. In this role, you will execute routine sample analysis, method validation, and laboratory activities in compliance with GxP requirements, SOPs, and applicable regulatory guidelines, while ensuring the generation of high-quality and reliable data. As a study-specific analyst, you will operate and maintain laboratory equipment, prepare and review study documentation, manage laboratory consumables and LIMS records, and support assay troubleshooting and continuous improvement initiatives. You will also contribute to SOP authoring and review, maintain accurate task and time records, support the training of new staff, and ensure adherence to quality, health and safety, and regulatory requirements at all times. • Perform bioanalytical methods in line with GLP, GCP, GMP, and SOPs., • Perform routine analyses and document all work according to GxP and SOP standards., • Operate and maintain laboratory instruments & environment as per SOPs., • Prepare project-related documentation, including lab manuals and reports., • Write and review SOPs and support method documentation., • Manage consumables, monitor stock levels, and maintain LIMS records., • Ensure compliance with health & safety guidelines and regulatory standards., • Act as Study specific analyst on assigned projects., • Train new personnel within area of responsibility when needed., • Record tasks and time accurately in time logging application., • Observe appropriate regulatory guidelines, SOPs, policies and study documentation., • Working in accordance with standard operating procedures (SOPs) by authoring, reviewing, and maintaining SOPs, guidance documents, and policies, as well as providing training and support to staff., • Master’s degree (MSc) in a scientific field, or 2-3 years of equivalent industry experience., • Skilled in analytical techniques and routine lab practices, including pipette handling, protocol adherence, and use of basic lab equipment (centrifuges, biosafety cabinets, plate washers, incubators etc.)., • Familiarity with advanced analytical instruments (e.g., LC/MS, microplate readers, flow cytometers, electrochemiluminescence analysers)., • Proficient in written and spoken English, with strong teamwork and negotiation skills., • Practical experience in GxP/GCLP-accredited environments. #J-18808-Ljbffr

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic, and labelling is accurate. Eurofins is dedicated to delivering testing services that contribute to the health and safety of society and the planet, and to its corporate responsibility to protect the environment and ensure diversity, equity, and inclusion across the entire network of Eurofins companies. Eurofins PSS Insourcing Solutions® is a global, award-winning insourcing solution. We place our skilled team directly at the client site, managing operations seamlessly and eliminating complexities. We ensure a strategic, long-term service commitment that delivers value directly at the client’ site, utilising their facilities, equipment, and methodologies, while maintaining the same service, expertise, and cGMP compliance available at the Eurofins facility. If you're an employee seeking an exceptional career journey, Eurofins PSS Insourcing Solutions® is your gateway to a future where innovation, collaboration, and success converge. Join us in a world where excellence knows no boundaries! We’re proud to be an armed forces-friendly place to work and welcome applications from reservists, armed forces veterans (including the wounded, injured and sick), as well as cadet instructors, and military spouses and partners. If you want to continue to help make our world a safer and healthier place, then apply for the role below and become a part of the extraordinary Eurofins network Unfortunately, we are unable to offer visa sponsorship for this role. This is a full time, permanent position, working a flexible 36.5 hour week, Monday – Friday. We are currently recruiting for an experienced, enthusiastic and innovative PAT Scientist. This is an exciting opportunity based at our client’s facility, a world class Pharmaceutical company based in Macclesfield. You will have a proven track record of delivering in-line and at-line analytical technology to pharmaceutical development projects and collaborating with project scientists to help support key Client projects. • You will provide real-time laboratory data analytics to support process chemistry activities, delivering high-density insights that enable accelerated process understanding and decision-making., • You can expect to collaborate closely with chemists and engineers to develop and implement Process Analytical Technology (PAT) solutions for complex drug substance projects, ensuring delivery against project milestones across early to late-stage development with reaction monitoring as well as continuous manufacturing., • You will utilise reaction monitoring and continuous manufacturing strategies to generate meaningful scientific insights that support client project requirements and drive successful outcomes., • The successful applicant will provide scientific and technical leadership within PAT, solving complex challenges, identifying key learnings, and sharing best practices across the wider department., • You can expect to demonstrate ownership of PAT strategy and development on drug substance projects, representing Chemical Development as required and providing expert challenge to enhance project delivery and innovation., • You will contribute to the ongoing development of Chemical Development capabilities by supporting current and future client portfolios, driving continuous improvement initiatives, and promoting new ways of working and scientific advancement., • You will hold a BSc, MSc or PhD in a relevant scientific discipline, with experience gained within Research & Development, manufacturing, academia, or the chemical and pharmaceutical industries., • You will have significant experience working within chemical or analytical laboratory environments, supporting analytical development for Active Pharmaceutical Ingredients (APIs) using techniques such as UPLC, GC and Karl Fischer analysis., • You will be expected to have practical expertise in Process Analytical Technology (PAT) and one or more key spectroscopic or analytical techniques, including NIR, Raman, IR, UV or LC, enabling you to provide specialist guidance to project teams., • You will have experience working with PAT applications in drug substance development, with exposure to quantitative model development, real-time process monitoring, and ideally scale-up activities within clinical or commercial manufacturing environments., • You will hold coding experience in Matlab, Python or similar programming languages, alongside a strong data-centric mindset and a willingness to further develop expertise in chemometrics and advanced data analysis., • You will have experience operating within GMP-regulated environments and a sound understanding of Safety, Health and Environmental (SHE) principles, demonstrating a commitment to maintaining the highest standards of compliance and safety. At Eurofins we are growing, innovating and always learning. We celebrate the achievements of our employees through annual long service awards, recognise our colleagues special life events, and we are committed to charitable causes through global fundraising activities. • Being part of a Reward and Recognition Scheme, recognising great work across our teams., • Holiday entitlement increases with service., • The option to opt into our Health Cash Plan, designed to help look after your everyday health and wellbeing. This allows you to claim back the cost of routine healthcare expenses such as dental check-ups, eye tests, glasses or contact lenses and other everyday medical treatments., • Life Assurance from day one, providing cover of four times your annual salary., • Automatic enrolment into our Company Pension Plan after three months (with the flexibility to opt out if you choose), • Access to our Employee Assistance Programme, offering 24/7 confidential support for both personal and work-related matters., • Being able to register your interest in volunteering days, which are designed to support employees who wish to do voluntary work during working hours as part of a wider strategy to contribute positively to the local community., • Free on-site car parking., • The opportunity to explore worldwide opportunities., • Everyone who joins our team also gets access to Perkbox, allowing you to save money all year round. Whether its supermarket savings or days out, the daily coffee or a summer holiday – there’s something to suit everyone’s lifestyle. Our people are the backbone of what we do, so it's incredibly important we find the right individuals to join us. As a potential new recruit you'll be invited to meet the team in the form of an assessment centre or a staged interview process dependent on the role and it's requirements, this will give you the opportunity to see what working for Eurofins is really like and enable us to get you know your key skills and strengths. As part of any recruitment process, the company collects and processes personal data relating to job applicants. The company is committed to being transparent about how it collects and uses that data and to meeting its data protection obligations. Eurofins network of companies believe in strength and innovation through diversity, being an Equal Opportunity Employer. We prohibit discrimination against employees or applications based on gender identity and/or expression, race, nationality, age, religion, sexual orientation, disability, and everything else that makes employees of Eurofins companies unique. For more information about Eurofins PSS® please visit our website and watch a message below from our Global Head, Beth Di Paolo. #J-18808-Ljbffr

Senior Scientist I (Membrane Protein Biochemist) Evotec Macclesfield, United Kingdom Design and execution of agreed work plans for the production and characterization of membrane proteins; Responsible for supporting multiple projects and may be asked to direct internal resources to achieve agreed goals; Will be expected to provide oversight of results to ensure quality to project specifications; Accountable, together with project counterparts, for the design of experiments, review of documentation, and client presentations. Will conduct thorough data analysis ahead of product release to internal or external customers; Proposes experimental designs and novel approaches to identify/advance best strategies in addition to planning/executing project deliverables; Responsible for the implementation of standalone scientific services and deliverables to customers; Where responsible for reports, will lead colleagues to co-develop plans for personal growth, aligned to business needs; Represent the company at scientific and/or business conferences; Presents and publishes as appropriate peer-reviewed science, increasing own and Evotec’s scientific reputation. Comprehensive knowledge of membrane protein biochemistry & biophysics with a proven ability to design and deliver results within agreed timelines and budget, meeting agreed quality criteria; Experience in the design of membrane protein constructs to optimise functional expression in eukaryotic expression systems; Extensive hands-on experience with insect and mammalian cell expression systems and multi-step chromatography purification. Proficiency with FPLC/HPLC purification systems. Analytical UHPLC experience is a plus; Expert in the optimisation of protein expression and purification workflows to obtain pure and stable membrane protein samples; Demonstrated success working with challenging membrane protein targets e.g. G protein-coupled receptors (GPCRs), ion channels, solute carriers, and integral membrane enzymes. A good understanding of different modalities (e.g. agonist/ antagonist for GPCRs, blockers/ activators for ion channels) across multiple therapeutic areas would be desirable; Experience with biochemical and biophysical characterization of purified membrane proteins using a range of techniques such as fluorescence size-exclusion chromatography (fSEC), DLS, nanoDSF, mass spectrometry, SPR, GCI, and microcalorimetry; Extensive knowledge of what constitutes a good membrane protein sample for structural (X-ray crystallography and/or cryo-EM) and biophysical studies (SPR/GCI, HDX-MS); Experience in the solubilization and stabilization of membrane proteins into co-polymers (e.g. Amphipols, Cubipols); Experience in developing protein binders (Fabs, VHHs, synthetic binders) for complex targets would be advantageous; Experience in high-throughput methodologies with associated data capture and handling; Experience with using in silico-based tools for sequence and structural analysis is desired (e.g. PyMOL, AlphaFold); Experience in preparing and executing work plans and building trusted partnerships with internal and external customers; Requires a track record of leading scientists across specialist fields; A track record of facilitating employee growth through co-development of personal development plans would be appreciated; Track record of successful problem-solving, high-quality science and influencing stakeholders and colleagues; Experience of scientific development and research work, ideally with publications on membrane proteins; Presents and publishes as appropriate peer-reviewed science, increasing own and Evotec’s scientific reputation. PhD in Biochemistry, Biophysics, Structural Biology or similar, with proven experience in membrane protein expression and purification with relevant experience within industry. Alternatively, a relevant first degree and several years of additional experience in drug discovery. Candidates with strong academic background and an excellent publication record are also encouraged to apply. #J-18808-Ljbffr

As an Analytical Scientist, you will contribute to the development of Globachem Discovery’s analytical services within the field of Crop Protection Research & Development. You will combine hands-on laboratory analysis, method development and scientific problem-solving to provide practical support across the business. You perform hands‑on laboratory analyses and provide practical analytical support for Globachem’s R&D activities. You develop and implement new analytical methods and services to support evolving R&D needs. You are responsible for maintaining the analytical instrumentation at Globachem Discovery. You apply different analytical techniques, including UPLC-MS, HPLC, GC-FID and UPLC-TQMS. You carry out high-throughput log D and solubility assays. You analyse proteins using appropriate analytical techniques. You collaborate with colleagues from different scientific disciplines to solve analytical challenges and deliver high-quality results. You will report to the Operating Officer. You hold a BSc, MSc or PhD in a relevant scientific discipline. 4 years of experience in the industry is desirable. You are proficient in Microsoft Office and have experience troubleshooting Waters and Agilent instruments in an analytical laboratory environment. You are eager to learn and confidently put new knowledge into practice. You are a strong team player with a can-do attitude and excellent problem-solving skills. You are proactive, use your initiative and are willing to think outside the box. You are eligible to work in the UK. #J-18808-Ljbffr

The SKAO Data Operations group is looking to employ a talented and driven DevOps engineer to join our team based in the SKAO Global Headquarters located at Jodrell Bank in the UK. With the SKA now in construction, the development of the global network of data centres - the SKA Regional Centre Network (SRCNet) - to support the operations of the SKA has entered an exciting phase. SRCNet is crucial to the success of the SKA. The observatory’s output data products will be too large for astronomers to download and process locally; scientists will rely on the SRCNet to make new scientific discoveries. In addition to efficiently storing and managing the Exabyte-scale archive of data products globally, the SRCNet will provide tools and services for astronomers to discover, visualise and process the SKA telescope data products, promoting the principles of open science and reproducibility of results. In order to support our delivery of the SRCNet, we are looking for someone with experience in operating production web services in a cloud ecosystem. This includes a good understanding of programming languages and frameworks commonly used in web service development, as well as the containerisation and orchestration technologies that enable us to manage, maintain and further develop these services. Complementing these, a background in scientific research is desirable, but not required. Due to the global nature of the SRCNet development effort, with multiple stakeholders and developers distributed globally, the successful candidate will possess strong organisational and communication skills, with a drive to collaborate with partner organisations and people to excel in this role. SKAO is committed to providing an inclusive and flexible working environment, meeting the requests of our colleagues whilst also fulfilling the needs and objectives of the Observatory. There are expected to be occasions where this role requires the post holder to work across different time zones and travel nationally and internationally as required (e.g. ~2-4 times a year). In line with SKAO policy, flexible working hours will be supported in agreement with the line manager. #J-18808-Ljbffr

Coatings, Coating, Materials, Chemical, Lab tech, lab technician, chemistry, chemist, production, scientific, Macclesfield, Buxton, Stockport, Leek, Congleton. Are you a from a Production Chemistry or similar background and looking to join a market leading company that will invest in your technical