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< Overview The Associate Director, Talent Acquisition Programs & Operations is responsible for designing, owning and evolving the core programs and infrastructure that shape hiring across Alnylam. This includes end-to-end ownership of global TA programs, spanning candidate experience, interview and assessment practices, hiring team enablement, emerging talent, and extended workforce. This hands-on leadership role ensures programs are not only well-designed but consistently executed and continuously improved and a tremendous opportunity for someone who can operate at both a detailed and systems level-keeping things moving while identifying practical ways to simplify and scale. They will ensure the recruiting infrastructure is highly performing, tech-enabled, and scalable. This is a hybrid role based in Cambridge, MA with 2 days/week onsite. Key Responsibilities TA Program Strategy & Execution • Own and evolve Alnylam's core TA programs, including candidate experience, structured interviewing and assessment, hiring manager and hiring team enablement, and emerging talent., • Translate hiring strategy into scalable and repeatable programs that drive consistency and quality across regions and functions., • Partner with TA, HRBPs and business leaders to identify gaps and continuously refine programs based on feedback and outcomes., • Drive adoption and accountability for programs across TA Partners, coordinators and hiring teams. Candidate Experience & Team Leadership • Lead and develop a team of Candidate Experience Coordinators responsible for interview scheduling and candidate logistics., • Set clear service expectations, SLAs, and quality standards) to ensure efficient, consistent, and accountable delivery., • Ensure a high-quality, consistent candidate experience across all touchpoints., • Partner with TA leadership and HR Ops to identify friction points in the candidate journey and build scalable, tech-enabled solutions. TA Systems & Process Ownership (Global) • Enable TA programs through effective systems and workflows; own end-to-end TA operations: requisition creation through to onboarding., • Own day-to-day administration and optimization of the ATS (Greenhouse)., • Maintain workflows, templates, interview stages, and system configurations., • Serve as primary point of contact for system support and enhancements., • Partner with HRIS/Itto ensure integrations, updates, and data flows support program insights and execution., • Identify and implement practical process improvements to drive efficiency and consistency., • Stay ahead of industry advancements in recruiting and translate innovations into practical deployments that reduce recruiter load and increase quality of hire. Training & Enablement • Design and deliver enablement programs for recruiters, coordinators, hiring managers and interview teams focused on tools, best practices, structured interviewing, and AI-enhanced workflows., • Maintain and evolve TA playbooks, toolkits, and resources to support consistent program adoption., • Embed new tools, technologies , and AI capabilities into enablement programs to drive adoption., • Evolve onboarding and training materials for new TA team members. Vendor & Program Management • Manage key TA vendor relationships (e.g., background checks, tools, agencies)., • Oversee background check process and ensure timely, compliant execution., • Lead Emerging Talent Programs, guiding Program Manager to continuously elevate and strategically evolve our program offerings and process., • Lead oversight of global non-employee (contractor) hiring processes and partnerships, optimize as compliant, talent-driven programs. Employer Brand • Drive design and execution of employer branding efforts in partnership with Corporate Communications team., • Ensure consistency in candidate-facing materials and communication. Qualifications • 8-10+ years of experience in Talent Acquisition, TA Operations, or HR Operations, • Strong hands-on experience with ATS administration (Greenhouse preferred), • Ability to manage multiple priorities and operate in a fast-paced environment; exceptionally organized and detailed orientated, • Passion for continuous improvement, emerging tech, and operational integrity, • Experience leading recruiting operations teams, preferably in public, regulated environments, • Exceptional cross-functional project leadership and systems thinking ability, • Proven ability to improve processes and drive operational consistency, • Exposure to AI ethics, explainability, and fairness in automated decision systems, • Experience working with data and reporting #LI-MH1 #LI-Hybrid U.S. Pay Range $157,300.00 - $212,700.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

At Zelis, we Get Stuff Done. So, let's get to it! A Little About Us Zelis is modernizing the healthcare financial experience across payers, providers, and healthcare consumers. We serve more than 750 payers, including the top five national health plans, regional health plans, TPAs and millions of healthcare providers and consumers across our platform of solutions. Zelis sees across the system to identify, optimize, and solve problems holistically with technology built by healthcare experts - driving real, measurable results for clients. A Little About You You bring a unique blend of personality and professional expertise to your work, inspiring others with your passion and dedication. Your career is a testament to your diverse experiences, community involvement, and the valuable lessons you've learned along the way. You are more than just your resume; you are a reflection of your achievements, the knowledge you've gained, and the personal interests that shape who you are. Position Overview The Strategic Client Executive (SCE) role will serve as the primary point of contact for Zelis clients for their assigned book of business, which consists of large complex payers with many Zelis solutions. The SCE will manage a strategic book of business comprised of vertically aligned clients and will drive growth for Zelis by achieving annual revenue targets, ensuring client retention, fostering growth with additional products and services, and ensure Zelis is always meeting and/or exceeding client expectations while driving a superior OneZelis customer experience. The SCE will develop and maintain critical internal and external relationships to sustain and build upon Zelis' value proposition and work collaboratively across the enterprise to achieve their clients' goals and objectives. RESPONSIBILITIES: Single point of contact for the management and orchestration of Zelis services overseeing relationships, operations, financial plans and strategy. Owns the client relationship, including all short- and long-term strategies and key client relationships. * Client Relationship Building: Maximize the breadth and depth of relationships by working closely with clients to intimately understand their business strategies, needs, and challenges as well as how Zelis supports the achievement of those goals * Revenue Management: Manage and oversee revenue targets, including budgets, forecasts, and product utilization review for the assigned book of business * Client Renewals & Retention: Responsible for client renewals and retention. Successfully lead contract negotiations and manage the complete life cycle to renew client agreements while looking for ways to expand the partnership. * Risk Identification and Mitigation: Proactively identify and mitigate risks such as volume decreases, service gaps, and changes in client relationships * Product Knowledge & Optimization: Drive revenue growth through existing product optimization, understand and communicate key differentiators, product strategy, features, and functionality * Client Growth: Successfully uncover and qualify opportunities for growth to deliver great client value. Collaborate with sales to present innovative solutions and grow existing client base. Identify up and cross-sell opportunities to flag for Sales. * Client Value: Effectively illustrate and validate client outcomes consistently, leveraging client reporting and knowledge of client's business goals and measures * Conduct Client Business Reviews: Conduct and lead all client business reviews and account plans to optimize value with the client's book of business * Client Advocacy: Ensure industry leading quality service delivery and client satisfaction; measurements include, proactive client management, timely escalation and resolution of issues, and nurture clients into loyal promoters. Secure client references and permission in support of key Zelis initiatives and case studies as needed. Attributes to be successful in role: * Deep Understanding of the Client's Business: Understand the client in terms of markets they operate in, competitors, objectives, and challenges. Successfully build strategic account plans to fully understand client's pain and business drivers. * Develop Trusting Relationships: Cultivates deep relationships with clients and team. * Executive Communicator: Proactively communicates. Can effectively prepare and present communications to clients and executive leadership teams. * Problem Solver: The ability to offer and communicate compelling solutions to client challenges is invaluable * Industry Knowledge: Keeping an ear to the ground in terms of market intelligence and relevant industry news * Financial Acumen: Strong financial acumen and ability to interpret client financials. Commission-driven and motivated to achieve growth targets. * Innovative Thinking: Brings creative insight to client's businesses to help them deliver a competitive advantage * Collaborator: Actively partners across BUs to communicate client needs & issues, shares and provides awareness of external trends and competitor landscape * Troubleshooting: Forward looking, keeps an eye out for potential internal/external problems and managing potential concerns Skills/BACKGROUND: * Bachelor's degree in business or health care administration or related field. * 10+ years in client management role * Extremely knowledgeable in the Payer and Regional Health Plan space. Experience in working in healthcare a plus including insurance companies, or working with cost management, electronic payments, and/or healthcare communications solutions * Demonstrated success in revenue management and increased utilization within an assigned book of businessof enterprise and strategic clients * Excellent written and verbal communication skills. Excellent presentation, public speaking, and meeting management capabilities. Ability to tailor messages to audiences * Proven collaboration with key business partners: Sales, Operations, Product, Services, and Marketing * Ability to anticipate future trends and incorporate them into business review planning * Synthesizes complex issues and communicates clearly to both clients and internal stakeholders * Ability to communicate and interact formally and informally with VPs and Executive Leadership; demonstrates Enterprise thinking with ability to influence; proven ability to influence across a matrix as well as with leadership * Experience leveraging data and reporting to accurately identify client and industry trends; able to synthesize data into compelling narratives * Demonstrates sense of urgency and ability to multi-task and prioritize * Strong listening and comprehension skills, ability to understand and address client concerns, feedback, and appropriately manage discussions with clients * Travel: estimated 30-40% domestic [internal and external meetings]; Location: Remote Please note at this time we are unable to proceed with candidates who require visa sponsorship now or in the future. Location and Workplace Flexibility We have offices in Atlanta GA, Boston MA, Morristown NJ, Plano TX, St. Louis MO, St. Petersburg FL, and Hyderabad, India. We foster a hybrid and remote friendly culture, and all our employee's work locations are based on the needs of the position and determined by the Leadership team. In-office work and activities, if applicable, vary based on the work and team objectives in accordance with Company policies. Base Salary Range $127,000.00 - $160,550.00 At Zelis we are committed to providing fair and equitable compensation packages. The base salary range allows us to make an offer that considers multiple individualized factors, including experience, education, qualifications, as well as job-related and industry-related knowledge and skills, etc. Base pay is just one part of our Total Rewards package, which may also include discretionary bonus plans, commissions, or other incentives depending on the role. Zelis' full-time associates are eligible for a highly competitive benefits package as well, which demonstrates our commitment to our employees' health, well-being, and financial protection. The US-based benefits include a 401k plan with employer match, flexible paid time off, holidays, parental leaves, life and disability insurance, and health benefits including medical, dental, vision, and prescription drug coverage. Equal Employment Opportunity Zelis is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. We welcome applicants from all backgrounds and encourage you to apply even if you don't meet 100% of the qualifications for the role. We believe in the value of diverse perspectives and experiences and are committed to building an inclusive workplace for all. Accessibility Support We are dedicated to ensuring our application process is accessible to all candidates. If you are a qualified individual with a disability or a disabled veteran and require a reasonable accommodation with any part of the application and/or interview process, please email ___. Disclaimer The above statements are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not to be construed as an exhaustive list of all responsibilities, duties, and skills required of personnel so classified. All personnel may be required to perform duties outside of their normal responsibilities, duties, and skills from time to time.

Description This is an Institutional Account Manager position in a startup Pharma organization being built to launch a cardiovascular product in the critical care space. Reporting to the Syneos Health Area Business Director, the Account Manager will be responsible for engaging key stakeholders within complex hospital accounts, institutional systems and integrated delivery networks (IDNs). Responsibilities: • Maximize relationships with key academic institutions, IDNs and GPOs and leverage these relationships to generate increased demand and access for the product by targeting appropriate prescribers and decision influencers within the hospital., • Partner with health systems to influence heads of departments, service line leaders, RNs, floor directors, and hospital pharmacy to secure formulary access and pull through of product utilization in the Hospital., • Increase adoption and pull through of institutional/GPO contracts., • Partner with administrators within health systems to remove barriers to appropriate use of product., • Achieve and/or exceed targeted sales goals in an assigned territory by developing, implementing and executing an integrated territory business plan encompassing key accounts with the goal of maximizing sales., • Establish and maintain professional relationships with targeted physicians to maximize new business opportunities., • Achieve success in a complex, matrixed selling environment in which the need for collaboration and cross-functional discipline is critical. Cross-functional partners may consist of Market Access, Medical, Marketing and Operations colleagues., • Use data tools and insights, and other informational sources to determine strategies and tactics for business decision-making., • Demonstrate account-based selling skills (including group presentations, etc.). Build relationships in institutions aligned with customer segmentation., • Plan and organize activities to ensure regular and consistent coverage of the territory according to a plan of action., • Develop a complete understanding of the health care delivery system within each assigned customer, including the physician hierarchy, key pharmacy personnel, clinical nursing staff, etc., • Collaboratively build account plans with field colleagues and leadership, that will increase demand and patient care., • Develop deep product and competitor knowledge and understanding of local and regional market trends., • Manage territory budget to support sales and marketing activities., • Complete all administrative tasks in a timely manner., • Execute the company brand strategy and tactics within their assigned geographic area., • Participation in required training and development programs., • BA/BS degree required., • 5+ years pharmaceutical/biotech sales experience., • 2+ years cardiovascular sales experience in the Hospital setting is required., • Hospital/Institutional experience highly preferred., • Knowledge of formulary approval process and driving formulary approvals is preferred., • Must live within territory or within territory boundaries., • Proven track record of success in a high science competitive selling environment., • Ability to identify key decision makers, develop positive relationships and strong customer dedication., • Self-starter, highly motivated to succeed., • Strong communication, business analytics and account management skills. Why Syneos Health? Here, the work is challenging, and the pace is exhilarating. By joining one of our commercial teams, you're empowered to succeed with the support, resources, and autonomy that you need. The diversification and breadth of our new and existing partnerships create a multitude of career paths and employment opportunities. Syneos Health has launched more sales teams in the last 5 years across all major therapeutic areas than the top 25 pharma companies combined. Join our game-changing, global company dedicated to creating better, smarter, faster ways to get biopharmaceutical therapies to patients. Experience the thrill of knowing that your everyday efforts are contributing to improving patients' lives around the world. Work Here Matters Everywhere | How are you inspired to change lives? Syneos Health companies are affirmative action/equal opportunity employers (Minorities/Females/Veterans/Disabled) Syneos Health has a voluntary COVID-19 vaccination policy. We strongly encourage all employees to be fully vaccinated. Additionally, certain local governments or Syneos Health customers may have vaccine requirements that apply to some of our employees. These employees are required to submit proof of vaccination to Syneos Health and maintain compliance with these requirements. At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position will include a competitive compensation package, Health benefits to include Medical, Dental and Vision, Company match 401k, flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos Health complies with all applicable federal, state, and municipal paid sick time requirements. 400003347

< Overview Alnylam is pioneering RNA interference (RNAi) therapeutics and scaling for global impact across research, clinical development, manufacturing, and commercialization. Our Cybersecurity organization is evolving to match that ambition, and we're seeking a Senior Director of Identity & Access Management to define and drive our approach to a global digital identity strategy and implementation. The Senior Director, Identity & Access Management (IAM) is responsible for defining, delivering, and operating a comprehensive program that protects the organization, enables the business, and supports regulatory compliance. This role owns the IAM strategy and roadmap across workforce, non-employee, as well as application identities. This role reports to the VP/CISO and is accountable for defining a crossfunctional, technologyforward approach that enables innovation while managing complexity at scale. This is a hybrid role primarily based in our Cambridge, MA office. Responsibilities • Define and execute the enterprise IAM strategy and multi-year roadmap aligned to Zero Trust principles and business risk priorities., • Own identity lifecycle management for employees, contractors, and partners, including joiner/mover/leaver processes., • Lead identity governance, access certifications, segregation of duties, and policy enforcement across critical systems., • Oversee privileged access management (PAM) and service account governance to reduce systemic and insider risk., • Partner with HR, IT, Digital, Compliance, and Legal to ensure IAM controls support business operations and regulatory requirements., • Ensure IAM platforms are resilient, well-architected, and operationally mature, with clear SLAs and metrics., • Drive adoption of modern authentication, MFA, conditional access, and identity threat detection capabilities., • Build, lead, and develop a high-performing IAM team with strong technical and program management skills., • Serve as a trusted advisor to the CISO and leadership on identity-related risk and investment decisions., • Establish clear accountability, operating rhythms, and reporting for IAM initiatives and outcomes., • Influence without authority and effectively manage cross-functional dependencies. Qualifications • Bachelor's degree in computer science, information security, engineering, or related field. Master's degree or MBA preferred., • 15+ years of progressive experience in identity and access management, with 10+ years in a leadership role., • Industry-recognized certifications strongly preferred (e.g., CISSP, CCSP, SABSA, TOGAF, or equivalent)., • Deep knowledge of IAM concepts including IGA, PAM, MFA, CIAM, and directory services., • Experience operating IAM programs in regulated environments (pharma, biotech, healthcare, or similar)., • Strong understanding of frameworks such as NIST CSF, Zero Trust, SOX, HIPAA, and privacy regulations., • Proven ability to translate technical risk into business-relevant terms for executives. U.S. Pay Range $229,500.00 - $310,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview: At Alnylam Pharmaceuticals, we are leading the RNAi Revolution, developing innovative therapies that transform the lives of patients with rare and prevalent diseases. As a Federal Account Director, you will play a key role in executing our U.S. federal market access strategy, with a primary focus on assigned Department of Veterans Affairs (VA) VISN and VA Hospital accounts, as well as supporting Department of Defense (DoD) ecosystems where applicable. This position requires expertise in the federal healthcare landscape, including VA/DoD reimbursement dynamics, formulary processes, Criteria for Use (CFU), utilization management, and stakeholder engagement, particularly for therapies requiring administration by healthcare professionals under the medical benefit. You will focus on optimizing access and appropriate utilization of Alnylam's HCP-administered products by ensuring compliant application of the VA National Formulary and CFU at your assigned accounts. In collaboration with cross-functional partners, you will educate site administrators, department chairs, and clinical influencers on the value proposition of Alnylam products for Veterans and service members. You will also support cross-functional pull-through efforts, contribute to federal access strategies, and provide insights to inform broader team initiatives. This role demands agility to navigate evolving policies, market conditions, and federal requirements while identifying opportunities to enhance product utilization. You will collaborate with internal teams, including sales, medical affairs, health economics, and strategic accounts, to align with Alnylam's commercial objectives and mission to deliver groundbreaking RNAi therapeutics to patients in federal systems. This is a field-based remote position requiring up to 50-70% travel and reports to the Senior Director, Federal Accounts. Key Responsibilities: • Execute federal access strategies within assigned VISN and VA Hospital accounts to optimize patient access and appropriate utilization of Alnylam's portfolio., • Ensure compliant application of the VA National Formulary and Criteria for Use (CFU) for Alnylam products at the site level., • Partner with the cross-functional team to ensure that critical education is delivered to key stakeholders including site administrators, department chairs, and healthcare professionals. This education includes: disease-state education, clinical information, as well as administration requirements of Alnylam's therapies., • Analyze account-specific data, trends, and utilization metrics to identify opportunities for enhanced pull-through and appropriate use., • Collaborate with field sales, Regional Business Directors, and cross-functional partners to implement pull-through tactics and support sales performance in federal accounts., • Contribute to the development and execution of account plans, sharing insights and best practices with the federal team., • Support federal market development initiatives, including engagement with organizations such as the Association of Military Surgeons of the United States (AMSUS)., • Provide federal payer and account insights to market access, HEOR, patient services, and leadership teams to inform strategies and address gaps. Accountabilities: • Build and maintain multi-level relationships within assigned federal accounts (VISNs, VA Hospitals, and related DoD entities), positioning Alnylam as a trusted partner for HCP-administered innovations benefiting Veterans and service members., • Navigate federal provider structures to engage key decision-makers, influencers, and clinical stakeholders, fostering long-term partnerships that support Alnylam's current products and pipeline., • Prioritize account activities to ensure consistent, compliant implementation of national formulary and CFU, addressing site-specific needs for medical benefit therapies., • Collaborate with internal experts (e.g., Medical Affairs, national contracting, and policy teams) to support access positioning and medical policy alignment., • Deliver tailored education on the value proposition of Alnylam products, emphasizing benefits for patient populations served in federal settings., • Review sales, utilization, and trend data to uncover pull-through opportunities, developing tactics aligned with team KPIs., • Work with field sales teams to execute pull-through plans, providing training on federal payer dynamics, formulary processes, CFU requirements, and reimbursement for HCP-administered therapies., • Maintain compliance with all legal, regulatory, and company policies in stakeholder interactions and program execution., • Contribute to team knowledge sharing by documenting best practices, participating in training, and supporting pilot programs or initiatives. Qualifications: • Bachelor's degree required (business or science preferred); advanced degree (e.g., MBA, PharmD) a plus., • Minimum 7+ years of pharmaceutical/biotech experience, with at least 3 years in account management, payer access, or related roles; direct experience in VA/DoD or federal channels preferred., • Proven track record in managing complex accounts, influencing stakeholders, and driving results in healthcare environments., • In-depth knowledge of federal healthcare systems, including VA National Formulary, Criteria for Use (CFU), VISN dynamics, aprocurement process for HCP-administered therapies, medical benefit coverage, utilization management, site-of-care strategies, and reimbursement pathways., • Strong analytical skills to interpret data, identify opportunities, and develop actionable account plans., • Consultative approach to stakeholder engagement, with expertise in value communication and educational program delivery., • Understanding of payer economics, utilization management, and evolving U.S. policies impacting federal systems., • Comprehensive knowledge of pharmaceutical operations, including prescribing, regulations, supply chain, managed care, sales, and compliance., • Excellent communication, presentation, and relationship-building skills; ability to collaborate effectively in cross-functional teams. #LI-ST1 #LI-Remote U.S. Pay Range $211,500.00 - $286,100.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Senior Clinical Data Manager The Sr. CDM will lead and contribute to data management activities in support of Alnylam studies across all stages of clinical drug development. This position reports to the Director, Clinical Data Management. Summary of Key Responsibilities • Contribute to data management activities as a lead study data manager in support of Alnylam clinical studies, • Lead database build activities including leading cross-functional review of eCRF content, review of edit check specifications, and perform user acceptance testing, • Monitor data collection, coding, and cleaning by vendors through tracking of study metrics and targeted data reviews, • Oversight of database lock activities and ultimate archiving of study data, • Collaborate with internal and external partners, including Biostatistics, Statistical Programming, Clinical Operations, Medical, Quality Assurance, Global Patient Safety and Risk Management, and Regulatory Affairs; CROs, central and local laboratories, and other vendors, • Establish cross-functional, internal data review plans, coordinate data cuts/transfers, and conduct data reviews, • Review CRO data management plans, CRF completion guidelines, external data transfer specifications and other study documentation, • Contribute to development and implementation of department workflows and infrastructure strategy (such as preferred provider interactions, SOPs, and templates) that reflects data collection standards, consistent with industry best practice and regulation, • Represent data management and effectively communicate requirements, strategy, timelines and deliverables at internal cross-functional team meetings and meetings with external vendors, • Participate in the training of external vendors and site staff, • Participate in the drafting and/or review of timelines consistent with company goals and ensure all deliverables and milestones are met, • Review clinical protocols/amendments, clinical study reports, statistical analysis plans, etc., • Support GCP inspection readiness, • BS/BA in scientific discipline,, • At least 5 years related experience in a pharmaceutical/biologics/biotechnology company, • Experience working in clinical drug development through Phase 3 in an outsourced CRO model; experience with drug development in rare genetic diseases preferred, • Expert knowledge of eClinical processes, efficient design/build of an EDC data management system and other Clinical Trial/Data Management Systems, • Knowledge and understanding of regulations and industry/adopted data standards such as CDISC, SDTM, and CDASH, • Experience working with Oracle InForm and Medidata Rave, • Experience using standardized medical terminology, including MedDRA and WHODrug, • Experience working with MSOffice Suite (Excel, Word, PowerPoint) and familiarity with MS Project, • Excellent written and oral communications skills, • Highly motivated and flexible, with excellent organizational and time management skills, • Ability to work independently and as part of a multi-disciplinary team, • Understanding ofICH GCP as well as general knowledge of industry practices and standards, • Knowledge and understanding of regulatory requirements and expectations for clinical data systems including 21 CFR Part 11, • NDA/MAA experience #LI-AB1 #LI-Hybrid U.S. Pay Range $131,800.00 - $178,300.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview: We are seeking a strategic, results-driven IT leader to own the technology vision and execution for Finance. This leader will serve as a crucial bridge between technical capabilities and strategic business needs, partnering directly with the CFO and Finance Leadership Team as both a strategic business partner and the architect of our financial technology ecosystem. The Sr. Director of Finance Technology will oversee the systems and data infrastructure that power core financial functions, ensuring operations are efficient, secure, compliant, and insight-driven. This role will drive a multi-year digital finance transformation leveraging SAP S/4HANA and Ariba, through our SAP Center of Excellence, while also establishing a modern financial data architecture that enables real-time analytics, predictive insights, and data-driven decision making across the enterprise. Responsibilities: Key Financial Functions: Responsibilities span the entire financial lifecycle of a company: • Accounting:They manage the systems that support fundamental accounting activities like the general ledger, accounts payable, and accounts receivable. This includes ensuring data integrity, automating processes for month-end and year-end close, and implementing systems for managing fixed assets. Their role is to ensure these systems provide accurate and auditable financial data., • Financial Planning & Analysis (FP&A):They are responsible for the technology that enables budgeting, forecasting, and financial modeling. This includes implementing and maintaining systems that allow for scenario planning, variance analysis (comparing actuals to budget), and generating strategic reports for senior leadership. They ensure the FP&A team has the right tools to provide actionable insights., • Procurement and Treasury:They oversee the technology for managing the entire procure-to-pay process, from purchasing and invoicing to payments. For treasury, they manage systems for cash management, foreign exchange, and debt management, ensuring financial liquidity and minimizing risk., • Compliance and Reporting:This is a critical function. They are accountable for the systems that ensure financial operations comply with regulatory requirements (e.g., SOX, GAAP). This includes implementing robust controls within the systems, managing audit trails, and ensuring the timely and accurate generation of financial statements and regulatory reports. Key Financial Systems Include: • Enterprise Resource Planning (ERP) Systems (S4 Hana):This is the backbone of most financial operations. They are responsible for the full lifecycle of the ERP, from selection and implementation to upgrades and ongoing maintenance. This includes managing modules for finance, supply chain, human resources, and more. A key aspect is integrating the ERP with other business applications to ensure a single source of truth for financial data., • Project Portfolio Management (PPM) Systems:They manage PPM systems to provide visibility into project spending and capital allocation. This allows for real-time tracking of project budgets, resource utilization, and ROI, ensuring that technology investments align with the company's strategic goals and are on track to deliver value., • Reporting and Business Intelligence (BI) Tools:They select and manage BI and data visualization tools in alignment with the IT strategy that transform raw financial data into meaningful dashboards and reports. This enables financial and business leaders to make data-driven decisions. They ensure data is clean, secure, and easily accessible to those who need it., • Specialized Financial Applications:This leader will also be responsible for systems outside of ERP e.g. Meridian Tax, Adaptive Financial planning, Process Unity Third Party Risk Management Strategic Business Partnership & Technology Leadership: • Partner with Finance executives to translate business strategy into technology and data solutions, • Drive the roadmap and execution for Finance systems modernization, • Lead the SAP Center of Excellence, ensuring optimal value from our SAP investment Financial Data Management & Governance: • Own the strategy and architecture for financial data platforms, ensuring data quality, integrity, and accessibility across source systems, • Establish master data governance frameworks for financial data domains, • Design and implement data integration strategies that enable seamless flow between SAP, reporting platforms, and downstream systems, • Build financial data models that support both operational reporting and advanced analytics, • Strategic Planning & Execution:develop and execute the company's financial technology (FinTech) strategy, aligning it with business objectives. This includes evaluating and implementing new technologies to improve efficiency, reduce costs, and gain a competitive edge. They are responsible for the overall budget for financial technology and must demonstrate a strong return on investment (ROI)., • System Management:This includes overseeing the entire lifecycle of financial systems, from planning and design to deployment and ongoing maintenance. They ensure that systems are secure, compliant with regulations, and scalable to support future growth. This also involves managing vendor relationships and negotiating contracts for technology services., • Leadership & Team Management:lead and mentor a team of technology professionals, including developers, analysts, and project managers. Foster a culture of innovation and excellence, providing guidance, and ensuring their team has the necessary skills and resources to succeed. This also involves project management for large-scale financial system implementations., • Collaboration & Communication:act as a crucial link between the finance, accounting, and IT departments. They must be able to translate complex technical concepts to non-technical stakeholders and clearly articulate how technology solutions will meet business needs. They collaborate with cross-functional teams to identify and address technology needs, solve problems, and streamline processes., • Risk & Compliance:responsible for ensuring the security and integrity of all financial data. They implement and enforce internal controls, manage data security, and ensure all systems comply with relevant industry standards and regulations. They also develop disaster recovery and business continuity plans to protect financial operations from disruptions. Requirements: • 15+ years of progressive IT leadership, with aminimum of 10 years in Finance systems and ERP strategy., • Deep expertise inSAP S/4HANA Finance, including GL, AP, AR, Fixed Assets, Controlling, and integration with Procurement and Supply Chain., • Proven experience inlarge-scale ERP implementations, global rollouts, and process re-engineering., • Strong command offinancial operations- accounting, FP&A, treasury, procurement, compliance, and audit support., • Demonstrated ability to leverageadvanced analytics, BI tools, and data visualizationto drive insights., • Exceptionalexecutive presenceand ability to influence at the C-suite and Board level., • Bachelor's degree in IT, Finance, or related field; MBA or relevant professional certifications (e.g., SAP Certified Application Professional, PMP, ITIL) strongly preferred. #LI-Hybrid #LI-LN1 U.S. Pay Range $226,800.00 - $306,800.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< TheDirector, Web Platform Engineering will serve as the strategic and technical owner of Alnylam's global web ecosystem. This leader will evaluate currentstate capabilities, define and drive a unified, scalable futurestate web platform strategy, and ensure our platforms meet the highest standards of performance, compliance, and user experience. This role will partner across Customer Experience & Innovation, IT Data Management and Security, Marketing, Medical Affairs, Legal, Privacy, and external agencies to build a worldclass ecosystem that supports corporate, brand, and regional web experiences. Key Responsibilities Web Platform Strategy & Architecture • Conduct a comprehensive currentstate assessment of Alnylam's global web technology stack (CMS, hosting, analytics, consent management, DAM, personalization, integrations, and related tools)., • Define and maintain a futurestate web platform strategy aligned to global scale, localization needs, performance expectations, and compliance requirements., • Establish reference architectures, standards, and technical frameworks for corporate and brand sites across regions., • Design and operationalize, in partnership with Customer Experience & Innovation, a scalable global operating model for web technology- balancing central governance with regional agility., • Define roles, responsibilities, and working models across relevant cross-functional teams and agency partners., • Ensure all web platforms adhere to regulatory, privacy, and security standards (e.g., GxP, GDPR, HIPAA, cookie/consent frameworks)., • Lead governance for web change management, release planning, validation approaches, documentation standards, and operational controls., • Oversee enterprise web platform operations, including uptime, availability, site performance, incident response, and SLA adherence., • Build and manage KPIs for platform health, delivery velocity, quality, cost efficiency, and business value realization., • Manage relationships with CMS providers, hosting platforms, system integrators, and digital agencies., • Oversee RFPs, vendor selection, contract negotiations, and performance management., • Serve as a trusted advisor to senior leaders across Technology, Commercial, Corporate Communications, and regional teams., • Communicate complex technical concepts in a clear, accessible manner tailored to nontechnical audiences., • Provide leadership to matrixed teams supporting web platforms. Qualifications Required • 10+ years of experience in web technology, digital platforms, or enterprise digital solutions, with increasing leadership responsibility., • Demonstrated success leading global web platforms within regulated industries (pharma/biotech, healthcare, medical devices, or similarly regulated)., • Deep expertise with modern CMS platforms (e.g., Acquia/Drupal, Sitecore, AEM)., • Experience with:, • Cloud hosting (AWS, Azure), CDN, security, and web infrastructure, • Web analytics, tag management, and performance measurement, • Consent/privacy management tools, • DAM integrations and content workflows, • Strong understanding of GxP, validation methodologies, security frameworks, and privacy regulations for web ecosystems., • Experience scaling web platforms in a midsize or highgrowth organization., • Familiarity with headless, composable, or APIdriven architectures., • Handson experience integrating web platforms with CRM, CDP, marketing automation, and personalization systems., • Background in agile or productoriented delivery models., • Bachelor's degree required; advanced degree preferred. Key Competencies • Strategic thinking & enterprise architecture leadership, • Global operating model design & execution, • Regulatory, compliance, and risk management fluency, • Vendor, budget, and performance management, • Executiveready communication and influence, • Pragmatic, handson problem solving and ability to roll up your sleeves, • Ability to operate in a fastpaced, growing, patientfocused organization, • Location: Cambridge, MA (Hybrid role; 3 days/week onsite) #LI-Hybrid #LI-LN1 U.S. Pay Range $187,400.00 - $253,600.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview We're transforming our data organization from a traditional portfolio and service delivery model to a technical, engineering-led approach where leaders architect solutions, write code, and drive business value through hands-on contribution. This role is at the epicenter of that transformation. As Senior Director of Enterprise Architecture, you'll own the architecture capability across the enterprise, leading a small team of elite architects while personally contributing to the most challenging technical problems. You'll be accountable for designing and implementing the data platform, integration patterns, and software engineering standards that enable AI/ML capabilities, operational excellence, and pharmaceutical innovation from drug discovery through commercial operations. You'll work in a matrix organization where you own your architecture capabilities and are directly accountable for delivering scalable, reliable, and secure systems that drive measurable business value. This means partnering deeply with R&D, Clinical Operations, Manufacturing, Commercial, and IT to translate complex enterprise requirements into modern technical architectures. Reporting to the VP, Data & AI, this is a Hybrid role based in Cambridge, MA, with a target of 2-3 days onsite. Responsibilities • Own Enterprise Architecture Strategy and Execution: Define and execute enterprise architecture strategy spanning data platforms, integration architecture, cloud infrastructure, and software engineering standards. Architect end-to-end data solutions from ingestion through analytics and AI/ML consumption while establishing architecture standards, design patterns, and governance frameworks for a regulated pharmaceutical environment. Build and drive the technical roadmap aligned with business needs and 2030 transformation goals., • Architect and Build Production Data Platforms: Design and implement production-quality data platforms using modern DataOps and DevOps practices. Write production code (Python, SQL, Infrastructure as Code) for data pipelines, integration services, and platform automation. Design cloud infrastructure on AWS using Terraform/CloudFormation/CDK, build robust data pipelines using Airflow/dbt/Spark/Glue, and implement CI/CD pipelines with automated testing. Personally tackle complex technical challenges in data modeling, performance optimization, and system integration., • Lead and Develop World-Class Architecture Team: Build, mentor, and scale a team of 3-5 highly skilled enterprise architects and technical leads. Balance hands-on technical contribution (20-30% of time) with team leadership and strategic architecture. Provide technical mentorship on architecture patterns, data engineering practices, cloud infrastructure, and pharmaceutical domain knowledge. Foster a culture of engineering excellence and continuous improvement while leading from the front on the hardest technical problems., • Drive Strategic Business Partnership and Value Delivery: Partner with business and technology leaders across R&D, Clinical Operations, Manufacturing, Commercial, and IT totranslate complex requirements into scalable technical architectures. Identify architectural patterns that create the most value, communicate complex technical trade-offs to executive stakeholders, and drive data democratization and engineering best practices across the organization. Build credibility through demonstrated delivery of high-impact architectural solutions., • Establish Modern Data Architecture and Technology Standards: Lead evaluation and adoption of modern data technologies (Snowflake, Databricks, AWS services, modern data stack tools). Design reference architectures for common patterns including data ingestion, transformation, API integration, and event-driven systems. Implement APIs and integration patterns using REST, GraphQL, and event streaming (Kafka/Kinesis). Stay current with architecture trends and translate them into practical implementations that maximize organizational time-to-value., • Ensure Operational Excellence and Architecture Governance: Design for observability, monitoring, and operational resilience. Create architecture governance processes including design reviews, technical standards, and architecture decision records (ADRs). Manage technical debt while rapidly delivering new capabilities. Balance innovation with operational stability, security, and regulatory compliance in a GxP-regulated pharmaceutical environment., • Deliver in Matrix Organization with Collaborative Accountability: Work within the Data, AI and Enterprise Architecture team structure while maintaining accountability for architecture outcomes. Partner with AI/Analytics colleagues to ensure data platforms enable ML/AI capabilities. Collaborate with Data Platform teams on implementation of architecture standards. Coordinate with IT, Security, and Compliance on enterprise-wide initiatives while owning architecture delivery commitments. Qualifications • Bachelor's degree in Computer Science, Engineering, or related technical field; Master's degree preferred, • 10+ years of experience building enterprise data platforms and architectures, with 5+ years in leadership roles, • Expert-level experience with Snowflake (lakehouse implementation, data sharing, governance) and strong experience with Databricks (Delta Lake, Unity Catalog, workflows, ML integration), • Hands-on experience designing and implementing cloud data platforms on AWS (S3, Glue, EMR, Redshift, Kinesis, Lake Formation); AWS Solutions Architect Professional level or equivalent experience, • Highly skilled in Python and SQL with production-quality code standards; strong Infrastructure as Code expertise (Terraform, CloudFormation, or AWS CDK), • Experience implementing CI/CD pipelines (GitHub Actions, CircleCI, Jenkins, GitLab CI) and hands-on experience with containerization (Docker) and orchestration (Kubernetes, ECS), • Experience with data pipeline tools (Airflow, Prefect, dbt, or similar), API design patterns, microservices architecture, and event-driven systems, • Experience designing integration architectures for enterprise systems (SAP, Oracle, Workday, Salesforce, Veeva, or similar), • 5+ years leading architecture and engineering teams, including hands-on technical mentorship; proven ability to build and develop high-performing teams of 3-10 people, • Experience working in matrix organizations with cross-functional collaboration across AI/ML, data engineering, security, and IT infrastructure teams, • Demonstrated ability to translate complex business requirements into scalable technical solutions and communicate architecture decisions to executive audiences, • Experience operating in regulated environments (FDA, EMA, GxP requirements) Preferred: • Biotech, pharmaceutical, or life sciences industry experience, • Deep knowledge of architecture patterns in Clinical Development (EDC systems, CTMS, eTMF), Manufacturing (MES, LIMS, batch systems), Research (lab systems, genomic data platforms), or Commercial (CRM, marketing analytics, supply chain), • Understanding of pharmaceutical data types and systems including clinical trials, genomics, manufacturing, quality, and supply chain, • Expertise in modern data architecture concepts: data lakes, lakehouses, data mesh, streaming architectures, semantic layers, data virtualization, • Knowledge of data modeling approaches including dimensional modeling, Data Vault, normalized designs, and graph databases, • Experience with monitoring and observability tools (CloudWatch, Datadog, New Relic) and understanding of distributed systems and performance optimization #LI-Hybrid #LI-LN1 U.S. Pay Range $255,000.00 - $345,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview The Associate Director, GxP Audits and Inspection Excellence, serves as the lead for Alnylam's enterprise audit and inspection program, providing direction, governance, and oversight across all GxP domains. This role is responsible for establishing a unified, risk-based and inspection-ready framework that ensures consistent audit execution, proactive readiness, and transparent Quality oversight aligned with global regulatory expectations. The Associate Director, reporting to the Head of Audits, Inspection Excellence and QMS (AIQ), leads and directly manages the GxP Audit and Inspection Excellence team. They partner closely with R&D QA, PV QA, Quality Operations, Manufacturing and Technical Operations, Supply Chain, and Quality Technology & Analytics. This role drives standardization, improves inspection transparency, develops advanced audit capabilities, and ensures the organization is prepared for evolving global regulatory scrutiny. This is a hybrid position and will primarily be located in Cambridge, MA Key Responsibilities • Serve as the lead for GxP Audits & Inspection Excellence, providing strategic direction, governance, and oversight across all audit and inspection activities., • Lead development and execution of the enterprise risk-based audit strategy, consolidating the GxP audit universe and ensuring consistency across internal and external audits., • Oversee global inspection readiness programs, including readiness strategies, cross-functional preparation, and standardized inspection management processes., • Ensure consistent global management of regulatory inspections, including documentation readiness, backroom operations, evidence management, and communication pathways., • Govern post inspection activities, including response quality, commitment tracking, timeliness, and systemic issue identification., • Provide leadership and oversight of audit and inspection tools, systems, and dashboards, ensuring data integrity, transparency, and strategic insight., • Partner cross functionally to integrate audit and inspection findings into QMS processes, Quality Risk Management, and enterprise reporting., • Champion continuous improvement of audit and inspection procedures, templates, guidance, and training materials., • Oversee operational delivery of audits and inspections through management of the GxP Inspection Oversight & Audit Management team., • Ensure robust CAPA tracking and effectiveness evaluation following audits and inspections., • Provide senior level reporting, insights, and trend analysis to Quality leadership and governance forums., • Drive organizational alignment, competency development, and a culture of proactive inspection readiness across all GxP areas. Qualifications • Bachelor's degree in Life Sciences, Pharmacy, Engineering, or related field; advanced degree preferred., • 10 years of experience in pharmaceutical/biotechnology Quality Assurance with significant focus on GxP audits, regulatory inspections, and quality systems., • Demonstrated leadership of enterprise or multi-GxP audit programs, including risk based planning, supplier oversight, and global audit execution., • Strong understanding of global regulatory frameworks and inspection expectations (e.g., FDA, EMA, MHRA, ICH, PIC/S)., • Proven experience developing and maturing inspection readiness programs and leading cross functional teams through inspections., • Proficiency with electronic audit and inspection management systems and QMS platforms (e.g., Veeva, ReadyRoom, eQMS)., • Strong communication, facilitation, and stakeholder management skills with the ability to influence without direct authority., • Demonstrated ability to lead, mentor, and develop team members, promoting high performance and continuous improvement., • Ability to operate effectively in a dynamic, fast paced, and highly cross functional environment., • Ability to travel domestically and internationally up to approximately 20%. #LI-LJ1 #LI-Hybrid U.S. Pay Range $164,500.00 - $222,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview Alnylam is the world's leading RNA interference (RNAi) company, dedicated to transforming the lives of patients through innovative medicines. As Alnylam continues to expand its global development and regulatory footprint, Regulatory Sciences supports increasing portfolio complexity, global regulatory engagement, and heightened expectations for data quality, compliance, and operational efficiency. The Director, Regulatory Sciences Technology will play a critical role in shaping and executing the technology strategy supporting Regulatory Affairs, Safety, and Medical Writing. This role serves as the primary technology leader and business partner for Regulatory Sciences, ensuring that systems, data, and digital capabilities enable compliant, efficient, and insightdriven regulatory operations across the product lifecycle. Success in this role requires a combination of strong Regulatory Sciences business acumen and deep technical fluency across regulated platforms, data integration, and documentcentric workflows, enabling the organization to operate at global scale while meeting evolving regulatory expectations. Key Responsibilities • Serve as the primary technology leader and business partner for Regulatory Sciences, building strong relationships with leadership across Regulatory Affairs, Safety, and Medical Writing to understand objectives, priorities, and technology needs., • Develop deep expertise in Regulatory Sciences business processes, proactively identifying opportunities where technology, data, and automation can improve compliance, efficiency, and submission quality., • Lead the delivery, support, and continuous improvement of Regulatory Sciences technology platforms (e.g., regulatory information management, safety systems, document and submission platforms), providing hands-on technical leadership and architectural guidance to ensure solutions are scalable, compliant, and audit-ready., • Drive adoption of the technology operating model within Regulatory Sciences, emphasizing centralized governance, in-house leadership, and close alignment with enterprise Technology, Data, and Quality teams., • Oversee the lifecycle of Regulatory Sciences technology solutions, including requirements gathering, vendor management, implementation, and ongoing support, with a focus on architecture integrity, data consistency, and inspection readiness., • Establish and enforce technology governance, standards, and best practices, including data privacy, security, validation, and compliance with global regulatory requirements. Regulatory Data, Content & Architecture Leadership • Provide technical leadership in the design and evolution of Regulatory Sciences data and content architectures, including structured regulatory data, submission metadata, safety case data, and document management workflows., • Partner with Data and Analytics teams to enable cross-system linkage and reporting across regulatory, safety, and clinical domains, while maintaining clear data ownership and compliance boundaries., • Enable technology capabilities that support regulatory intelligence, submission planning, inspection readiness, and lifecycle management., • Translate complex technical and compliance considerations into clear guidance for Regulatory Sciences leadership and operational teams. Cross-Functional & Lifecycle Collaboration • Collaborate closely with Clinical, Medical Affairs, Quality, and Commercial Technology teams to ensure Regulatory Sciences systems integrate effectively across the product lifecycle., • Support global regulatory operations by enabling technology solutions that scale across regions, health authorities, and submission types., • Partner with Quality, Security, and Validation teams to ensure technology solutions meet internal and external compliance expectations. Vendor, Platform & Operational Leadership • Collaborate with external vendors and internal technology teams to deliver Regulatory Sciences platform integrations and enhancements., • Support and guide Application Support teams and external partners, bringing sufficient technical depth to challenge solution designs, assess architectural and data tradeoffs, and ensure vendor-delivered capabilities meet Alnylam's compliance, scalability, and integration standards., • Proactively identify functional and technical gaps in Regulatory Sciences systems and recommend improvements., • Use root cause analysis and troubleshooting skills to resolve complex functional and technical issues., • Act as an escalation point for critical technology issues impacting Regulatory Sciences operations. Qualifications • Degree in Information Technology, Computer Science, Data Science, or related field, with experience in regulated life sciences environments., • Proven business analysis skills with strong analytical and problem-solving abilities., • Effective prioritization and project management skills., • Significant experience delivering and supporting GxP-regulated technology platforms in healthcare or biopharma., • Demonstrated ability to operate at both strategic and technical depth, including evaluating architecture options, validation approaches, and data integration strategies., • Experience supporting Regulatory Affairs, Safety, Medical Writing, or adjacent development functions preferred., • Familiarity with regulatory systems (e.g., RIM, safety databases, document/submission platforms) and enterprise data ecosystems., • Strong team player with the ability to maintain effective relationships at all levels., • Ability to anticipate, understand, and address changing regulatory and business needs., • Excellent communication skills, both oral and written., • Leadership and/or supervisory experience. #LI-LN1 U.S. Pay Range $187,400.00 - $253,600.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Associate Director, Medical Insights and Analytics Position Summary The Associate Director, Medical Insights and Analytics is an accomplished individual contributor within the Global Medical Excellence team. This role is accountable for executing and scaling Medical Affairs business analytics in alignment with the Medical Excellence roadmap and governance model. Operating within established Medical Excellence frameworks, this role leads high-quality analytics execution and partners across Field Excellence, Medical Operations, regional Medical teams, and cross-functional stakeholders to enable effective Medical strategy and execution across regions and therapeutic areas. The Associate Director independently designs and delivers complex analyses to ensure analytical rigor, methodological consistency, and decision-relevant insights aligned with Medical Affairs priorities. Key Responsibilities Medical Affairs Analytics Operationalization • Operationalize and scale established Medical Affairs analytics standards, frameworks, and methodologies across regions and business units., • Ensure adherence to defined analytics standards, methodological consistency, and quality control across Medical Excellence-led initiatives., • Partner with Field Excellence and other Medical stakeholders to translate agreed business priorities into aligned analytical workplans within the Medical Excellence governance framework., • Design and execute complex medical analytics using real-world data, Medical engagement data, digital data, and operational data to identify trends, patterns, and relationships relevant to Medical Affairs strategy and execution., • Apply established Medical Excellence frameworks to translate defined business questions into structured, fit-for-purpose analytical plans, oversee delivery, and distill actionable insights to inform Medical leadership discussions., • Apply rigorous statistical and analytical methodologies to address Medical questions related to field engagement, scientific communications, launch support, care gap analysis, KPI tracking, and impact evaluation., • Lead structured aggregation and analytical synthesis of medical insights data, ensuring insights are systematically analyzed and translated into actionable themes., • Serve as the dedicated analytics execution partner to Medical Excellence initiatives, embedding analytics throughout initiative design and execution., • Support the Director, Medical Excellence in strategy and planning discussions with regional and therapeutic-area leadership by providing analytics expertise., • Collaborate with the Associate Director, Field Excellence and other stakeholders to translate field priorities into analytical plans., • Provide analytical expertise and vendor oversight to support field prioritization analyses, impact summaries, rapid-turnaround analyses, and initiative evaluations., • Manage and oversee external analytics vendors, including review of analytical approaches, validation of outputs, and quality assurance., • Approve vendor deliverables to ensure analytical accuracy, methodological rigor, and alignment with defined Medical Excellence objectives and timelines., • Partner with Data Management, Strategic Technologies, and CX&I to ensure Medical datasets are appropriately governed and structured to support defined analytics use cases., • Partner with Advanced Analytics and Data Science (AADS) to align on shared data infrastructure and technical capabilities where appropriate, while maintaining accountability for Medical-specific analytical design, interpretation, and application across Medical data sources., • Contribute Medical Affairs analytical expertise to enterprise AI and advanced analytics initiatives in alignment with enterprise governance and Medical Excellence priorities., • Support the evolution of scalable analytical tools and impact measurement approaches within Medical Excellence., • Bachelor's degree in data science, biostatistics, business analytics, life sciences, public health, or a related field required; advanced degree strongly preferred., • Minimum 6-8 years of experience in analytics or medically focused data science roles within the life sciences industry or academia; consulting experience in life sciences, healthcare, or strategy-focused analytics preferred., • Prior experience supporting Medical Affairs or related healthcare functions through analytics, with understanding of Medical Affairs objectives, engagement models, and compliance considerations., • Demonstrated expertise in analytics methodologies, real-world data, medical insights analysis, and impact measurement., • Strong hands-on analytical capability, including independent execution of complex analyses and experience working directly with large healthcare datasets (e.g., claims, CRM, digital engagement data)., • Proficiency in data and analytics tools (e.g., Python, SQL, Power BI), with demonstrated experience independently applying predictive modeling, descriptive and inferential statistics, time series analysis, and advanced data mining techniques., • Experience reviewing and validating vendor-generated analytical outputs for methodological rigor and accuracy., • Advanced ability to synthesize complex analyses into clear, compelling narratives for senior stakeholders., • Strong understanding of pharmaceutical compliance considerations and data governance standards., • Ability to operate effectively in a matrixed, cross-functional environment and influence without formal authority. #LI-AB1 #LI-Hybrid U.S. Pay Range $165,800.00 - $224,200.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview Alnylam is seeking an experienced labeling professional to join our labeling strategy team. This team is responsible for developing initial product label content and strategy through the Target Label Process (TLP). The ideal candidate will possess expertise in drafting label content and leading cross-functional teams within a larger development framework. In this role, you will work closely with labeling operations, compliance teams, and various internal stakeholders. Key Responsibilities • Represent Global Labeling on product-specific Global Regulatory Teams and other cross-functional product, development, and product safety teams as appropriate., • In collaboration with Global Regulatory Leads and Core Labeling Teams (CLTs): create, revise, and maintain Company Core Data Sheets (CCDS) for Alnylam's products., • Develop labeling strategies and Target Label Profiles., • Provide strategic guidance to Core Labeling Teams regarding new and revised labeling regulations, competitor labeling, and labeling trends., • Review and communicate impact of changes in health authority labelling legislation or guidelines on Alnylam's products[KM1.1]., • Lead with development and maintenance of regional labeling that aligns with the CCDS and meets the requirements of health authorities., • Lead with preparation of responses to labeling-related queries from health authorities., • Coordinate labeling activities (e.g., labeling supplements, new labeling development) with internal and external alliance partners as required., • Partner with Regulatory Technology and Operations and Supply Chain to ensure submission-ready labeling components comply with regulatory requirements. Assist with preparation of submissions to health authorities, as needed., • Track data sources supporting labeling claims, history of labeling negotiations and changes, and reasons for differences in local labeling., • Support the growth of the Global Labeling function and help design/build systems and processes. Qualifications • BS/BA degree (science or related discipline preferred), graduate degree desirable., • Professional experience in biopharmaceutical industry in fields of Regulatory Affairs, Pharmacovigilance, and/or Medical Writing/Communications., • Experience in Regulatory Affairs, including at least 2 years' experience in a Labeling role[KM1.1] responsible for developing and drafting prescribing information content., • Familiarity with US, EU and Global regulations, standards and guidance documents related to labeling of pharmaceutical products., • Keep up to date on emerging clinical and other data, product safety, changes in manufacturing, and completion of post-marketing commitments and requirements for Alnylam products that may trigger changes to the CCDS and regional or local labeling.[KM2.1], • Must be detail-oriented and able to multi-task and manage multiple projects. $170,900.00 - $231,300.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview: The Associate Director, Emerging Modalities CMC Operations will lead cross-functional planning and operational execution for emerging modalities and other non-platform programs. This role is responsible for driving development readiness by coordinating activities across Research, CMC sub-functions, Bio(Analytical), Regulatory, and external partners, including selection and management of CDMOs. This role serves as the operational backbone for emerging modality programs, ensuring cross-functional activities are aligned to program strategy, development milestones, and external execution needs. The individual will build and manage integrated development plans, support development readiness packages, help shape external partner and CDMO strategy for early-phase programs, and ensure programs have a credible, phase-appropriate path into early development and Phase I execution. This role is intended to reduce late-stage CMC surprises, strengthen planning for emerging modalities, and enable more structured and repeatable pathways for programs beyond core RNAi. Responsibilities: • Drive cross-functional operational planning for emerging modalities through early development, including external execution at CDMOs and coordination of internal stakeholders., • Build, maintain, and track integrated timelines across Research, CMC, Manufacturing, Bio(Analytical), Regulatory, and external partners., • Partner closely with the CMC lead, Program Management, and technical subject matter experts to develop development readiness packages and aligned execution plans, • Work in close collaboration with CMC sub-functions to ensure clear and phase-appropriate readiness for analytical methods, raw materials, process development, and manufacturing activities., • Help define and execute external partner and CDMO strategy for novel modalities, including partner evaluation, onboarding, and oversight., • Coordinate phase-appropriate activities to reduce program risk and support efficient progression into early clinical development and Phase I., • Identify key risks, dependencies, and operational gaps, and elevate clear recommendations to leadership., • Support governance, meeting structure, milestone tracking, and cross-functional follow-through for modality-focused programs., • Develop new tools, templates, and playbooks that improve consistency, repeatability, and decision-making across emerging modality programs., • Facilitate stakeholder alignment to support timely advance, redesign, or stop decisions before formal development entry. Qualifications: • Bachelor's Degree in life sciences, pharmaceutical sciences, chemical engineering, bioengineering, or related field with a minimum of 8 years of relevant industry experience. Master's Degree is preferred., • Technical knowledge of new modalities and ability to have seamless conversation with internal and external stakeholders., • Relevant industry experience in CMC, pharmaceutical development, technical operations, program leadership, or external development., • Excellent communication skills and solid experience working on cross-functional drug development teams., • Experience managing complex timelines, dependencies, and external partners (CDMOs)., • Strong understanding of early-phase CMC development and modality-related development risk., • Ability to evaluate CDMOs for early phase work and onboard partners rapidly., • Experience in working with emerging modalities such as Antibody Oligo Conjugates (AOCs), Peptide Oligo Conjugates (POCs), peptide, biologics or related platforms., • Ability to translate technical complexity into clear plans, risks & decisions for leadership., • Excellent communication, organizational, and influencing skills. #LI-KB1 #LI-Hybrid U.S. Pay Range $161,500.00 - $218,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview The Director, Head of Global Trade Compliance and Strategy is a key supply chain leader responsible for designing, implementing, and overseeing the company's global trade compliance program while shaping trade-related strategy to support growth, resilience, and innovation. This role ensures full compliance with international trade regulations while enabling efficient, ethical, and scalable global operations across R&D, manufacturing, and commercial activities. This role will set the global trade policy and strategy direction, drive proactive regulatory engagement, and partner with senior and executive leadership across Supply Chain, Commercial, Legal, Finance, Tax, Regulatory, and Quality to align trade compliance strategies with business growth. The Director will lead a team of Trade Compliance professionals who represent Alnylam with relevant regulatory authorities, ensuring the company's operations meet all applicable import, export, customs, and sanctions regulations. Key Responsibilities Global Trade Compliance Program Leadership • Own and continuously enhance Alnylam's global trade compliance framework, including import/export policies, standards, and procedures aligned with U.S. CBP, OFAC, DEA, FDA, and relevant international agencies and programs (EU, UK, JP, etc)., • Maintain the governance model for global trade compliance, including oversight of risk assessment, monitoring, and executive-level reporting., • Ensure robust internal controls for classification, valuation, licensing, and documentation are in place across R&D, clinical, and commercial supply chains., • Partner with senior leaders across Global Supply Chain, Manufacturing, Tax, and Finance to embed compliance strategy into network design, sourcing, and product launch plans., • Collaborate with Legal, Policy, and Compliance teams to influence Alnylam's positions on global trade and regulatory policy., • Analyze and implement tariff mitigation and duty optimization strategies, including First Sale for Export, duty drawback, and Foreign Trade Zones (FTZs), to enhance supply chain efficiency and reduce costs., • Monitor international regulatory and geopolitical developments; Advise senior leadership regularly, providing strategic insights, business impacts, risk assessments, and recommendations that shape enterprise-level decision-making., • Establish KPIs to measure compliance performance, identify emerging risk, and drive continuous improvement across the team., • Support due diligence, onboarding, and qualification requirements for Logistics Service Providers (LSPs) as it relates to Trade Compliance, including compliance certifications, internal controls, and screening capabilities., • Lead and develop a global team of trade compliance professionals and regional specialists., • Build organizational capability through targeted training, knowledge sharing, and cross-functional engagement., • Partner with IT and Logistics to enable process deployment for global trade compliance operations, including supporting systems (i.e. SAP)., • Lead global process harmonization, technology enablement such as global trade management systems, and benchmarking initiatives to enhance program efficiency and scalability. Qualifications • Bachelor's degree with extensive related experience required; Master's or law degree is desirable., • Minimum 10 years of experience in international trade compliance, including 5+ years leading global operations in a regulated industry (pharmaceutical, biotech, or life sciences preferred)., • Deep expertise in U.S. import/export regulations (CBP, EAR, OFAC, FDA, DEA) and global trade frameworks (EU, UK, APAC)., • Experience in customs valuation planning, especially in supply and value chains involving IP, intercompany transactions, and other complex commercial arrangements like license and royalty agreements., • Previous collaboration with Tax, Legal, and accounting, finance groups to manage customs valuation planning is a plus, as is experience managing customs valuation for non-commercial goods (ex. clinical trial materials, research samples, unsold WIP)., • Proven success engaging with regulators and government agencies to shape or influence trade compliance policy outcomes., • Demonstrated ability to brief, influence, and align senior leaders on complex regulatory and risk management topics., • Licensed Customs Broker (LCB) certification is desirable. $192,400.00 - $260,400.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview Alnylam is seeking a strategic and pragmatic technology leader to serve as Senior Director, Lab-to-Product Platform & Operations Technology, a role that owns the core digital platforms, services, lab computing environment, and operational technologies that power laboratory operations across Research, CMC, and Quality Control, as well as digital enablement of plant-floor (shopfloor) operational technologies (OT). This scope extends beyond internal operations to include operational technology enablement, secure data exchange, workflow interoperability, and validated system readiness that support external execution partners-including CROs, external research labs, development collaborators, contract testing labs, and external manufacturing partners. This role is focused on operational platforms-the systems, integrations, partner connectivity, validated interfaces, computing environments, and services that ensure labs, plants, and external partners run reliably, compliantly, and efficiently. Scientific research platforms and enterprise manufacturing systems (e.g., MES and supply chain planning) are owned by their respective teams. This role ensures seamless interoperability, operational data flow, OT enablement, and validated integration frameworks across internal and external environments while maintaining clear ownership boundaries. This role is responsible for building and operating a modern Lab-to-Product operational platform that connects experiment execution, sample and materials workflows, QC testing, and plant operations - regardless of whether those activities occur internally or through external partners. This hybrid role is based primarily in Cambridge, MA, with regular engagement at our Cambridge labs and Norton/Alewife manufacturing sites, and direct interaction with external execution partners. Key Responsibilities • Lead the digital capabilities that support lab operations across Research, CMC, and QC, including LIMS, ELN/LES, sample & inventory management, registration, lab automation enablement, instrument integration, lab computing, lab system validation, and operational data capture., • Oversee plant-floor operational technologies (OT) such as equipment/instrument connectivity, environmental and facility monitoring interfaces, materials tracking, barcode/RFID data capture, and automated data collection (excluding MES and supply chain systems)., • Enable operational technology connectivity, workflow interoperability, and validated data exchange with CROs, external research labs, development partners, contract testing labs, and external manufacturers., • Support validated data handoffs, sample/material traceability, workflow tracking, and operational interfaces across hybrid (internal + external) execution models., • Ensure reliability, compliance, validated state, lifecycle management, and service continuity across internal systems and partner-connected operational interfaces., • Oversee lab/operational system validation activities in partnership with Quality to maintain GxP compliance and data integrity across all execution environments., • Architect and deliver the operational platform that connects experiment execution sample workflows QC testing plant operational activities external execution and release workflows., • Provide reusable platform components including metadata standards, workflow modules, instrument connectors, validated integration frameworks, and operational data pipelines that external partners can adopt or interface with., • Ensure seamless interoperability with:, • Scientific platforms owned by ReDev Technology, • Manufacturing/enterprise systems owned by Manufacturing/CMC/Supply Chain Technology, • External research, development, QC, and manufacturing partner systems, • Establish secure, scalable, validated patterns for partner connectivity (e.g., APIs, secure file exchange, partner portals, event/data streams)., • Build and develop talent and capabilities across product management, engineering/architecture, lab computing support, instrument connectivity, and operational platform engineering., • Define support, governance, onboarding, and escalation models for external partners, including SLAs and service continuity plans in collaboration with ReDev and TOQ., • Drive a culture centered on operational excellence, validation rigor, compliance, accountability, and pragmatic problem-solving., • Establish standards, governance, and best practices for lab/plant operational technology, including lab system validation frameworks., • Work closely with the Data & AI organization to ensure operational data - including external partner-generated data - is structured, contextualized, and AI-ready., • Implement consistent metadata, data capture, and validated interface practices across internal and external operations., • Enable cross-system visibility into workflows, materials, samples, and processes across internal labs, plants, and external partner networks., • Collaborate with ReDev Technology, Manufacturing/CMC/Supply Chain Technology, Quality, Tech Operations, Data/AI, Infrastructure, and Security to ensure cohesive integration and operational excellence., • Partner with ReDev and TOQ to define and support the digital operating model for CROs, external labs, contract testing labs, and external manufacturers., • Maintain clear ownership boundaries while ensuring the operational platform enables distributed execution., • Serve as a trusted partner to scientific, operational, and quality stakeholders - internally and externally. Qualifications Required • Bachelor's degree in Computer Science, Engineering, Life Sciences, or related field (or equivalent experience)., • 15+ years of progressive leadership experience in laboratory informatics, scientific operations, OT/plant-floor (shop floor) automation enablement, or manufacturing operational technology in biotech/pharma., • Deep expertise with lab operations systems (e.g., LIMS, ELN/LES, sample/inventory management, workflow orchestration), lab computing environments, instrument integration, and validated interfaces., • Experience supporting operational workflows across internal and external networks, including CROs, external research labs, contract testing labs, and/or external manufacturers., • Strong understanding of GxP, Computer System Validation (CSV), data integrity, interoperability, and operational data management., • Experience leading product management and engineering/architecture teams in regulated and non-regulated environments., • Proven track record delivering enterprise-scale operational platforms with measurable impact., • Exceptional communication, influence, and stakeholder-management skills., • Ability to balance long-term strategy with pragmatic execution. Preferred • Advanced degree in Computer Science, Engineering, or Life Sciences., • Experience supporting RNAi, oligonucleotide, or other advanced modality development or manufacturing., • Familiarity with modern integration architectures (APIs, event-driven patterns), lab automation frameworks, OT/plant-floor technologies, and emerging AI-driven automation., • Experience in environments where R&D, CMC, QC, Manufacturing, and external partners depend on shared operational platforms and validated systems. #LI-Hybrid #LI-LN1 U.S. Pay Range $226,800.00 - $306,800.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview Reporting to the Senior Director, U.S. Channel Distribution, Alnylam seeks an experienced and focused individual to manage processes and procedures, and act with a strategic mind-set in all aspects of optimizing the distribution strategies to provide optimal access for all patients. This individual is crucial in developing and executing integrated, evidence-based strategies and initiatives for assigned channel and distribution projects, ensuring consistency and compliance. This Associate Director will also lead strategic initiatives and projects, including vendor oversight, prioritization, and delivery of solutions that support business and future product launch objectives. This strategic contributor will have the opportunity to drive channel specific strategies, collaborating with internal partners and external vendors to support successful product launches and ongoing projects. The Associate Director must be effective in enhancing internal resources, including onboarding and training of new team members, and development of tools, processes, and best practices. The successful candidate must be passionate about science and deeply motivated by the quest of delivering value to patients and their families with the long-term success of the company in mind. Key Responsibilities • Ensure the effective operations of the US distribution network so that product flows from 3PL to customer, safely and reliably, • Ensure effective communication between Alnylam and external supply chain partners, • Troubleshoot issues, optimize daily operations, and support day-to-day business needs, • Develop, govern, and maintain SOPs, Working Instructions, and Channel Policies to leverage efficiencies and drive collaboration, while ensuring clarity, consistency, and compliance, • Develop and oversee new processes and workflow mappings, • Serve as the primary escalation point for field-identified channel and distribution issues, coordinating crossfunctional resolution strategies and driving timely and successful outcomes, • Support contractual and operational performance of our Specialty Distribution and Specialty Pharmacy partners, including Days on Hand targets, KPI monitoring, and continuous optimization of channel execution, • Partner closely with crossfunctional teams, including Payer, Field Reimbursement, Patient Services, Analytics, Legal, Supply Chain, Compliance, Field Sales, and Strategic Accounts, to align strategy, manage escalations, and deliver solutions, • Assess and track market and operational trends to inform proactive decision making, continuous improvement, and strategic and tactical planning, • Manage RFP process, as appropriate, • Liaise with Serialization Team to resolve DSCSA exceptions, • Lead Product Training / Global Safety Training / Disease State Training for channel partners, • Ensure compliance with all corporate policies and industry codes, in collaboration with Alnylam Legal, Regulatory and Compliance, • Enhance knowledge of current industry trends and anticipate future changes Required Qualifications • Pharmaceutical/biotech experience required, • Minimum of 10 years industry experience, including SOP development, process mapping, contract analysis, pharma trending analytics, KPI management, • Expertise in supply chain management including 3PLs, Specialty Distributors, Specialty Pharmacies and other customers, • Undergraduate degree required, • Strong leader with proven abilities to influence and create cross-functional alignment, • Demonstrated ability to assimilate and present complex information to higher level management and contribute to high-level discussions, • Ability to thrive in a fast-paced, high-profile environment, • Strong collaboration skills with the demonstrated ability to gather key stakeholder feedback and gain leadership alignment, • Ability to lead without authority, • Exceptional communication skills, both verbal and written, • Ability to produce board-ready presentation material, • Demonstrates strategic-thinking, problem-solving and decision-making skillsets, • Ability to travel up to 30% Preferred Qualifications: • Industry experience in Specialty Products, • Experience with supply chain management for rare disease medicines preferred, • Buy and Bill experience preferred Expectations • Clear Alignment with Alnylam Core Values:, • Commitment to People, • Innovation and Discovery, • Purposeful Urgency, • Open Culture, • Passion for Excellence, • The Associate Director, Channel Strategy and Operations will demonstrate effective self-starter and strategic planning skillsets, • Demonstrates ability to build relationships and influence colleagues across multiple functions and divisions Key Skills, Abilities and Competencies • Distribution Channel Dynamics:Knowledge of US pharmaceutical channel dynamics, data analytics and reimbursement environment, • Influence and Leadership:Influences without formal authority, able to integrate resources to achieve strategic objectives, and build/maintain strong relationships. Ability to establish close collaboration with strategic partners; able to inspire and align a diverse organization., • Business Acumen:Understanding of business analytics, possession of effective communication skills, and strong leadership skills, • Work Style:Works collaboratively across expertise areas and functions; seeks to advance higher goals; highly regarded across stakeholders both at senior and junior levels; inspires trust at all levels About Alnylam Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by "interfering" with mRNA that cause or contribute to disease. Since our founding in 2002,Alnylamhas led theRNAi Revolutionand continues to turn scientific possibility into reality. Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we have been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine's Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK - among others. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients. Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer. #LI-KB2 #LI-Remote U.S. Pay Range $168,300.00 - $227,700.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< The Senior Manager, CRM & Lifecycle Marketing is responsible for executing and optimizing lifecycle marketing programs across owned channels (email, SMS, direct mail), with a focus on building and delivering scalable, data-driven customer engagement. This role is a core operator within the Global Omnichannel model, partnering with business unit marketing teams and Omnichannel leads to translate defined journey strategies into activated, compliant, and measurable campaigns within enterprise CRM platforms. This is a hands-on campaign execution role with high visibility, focused on building and deploying lifecycle programs within IT-managed platforms, operating within defined strategy, platform architecture, and data models. • Execute and optimize multi-channel lifecycle programs aligned to defined brand strategies and omnichannel priorities, • Translate approved journey designs into activated campaigns, ensuring sequencing, timing, and audience alignment, • Support the scaling of lifecycle programs across acquisition, onboarding, engagement, retention, and reactivation, • Partner with U.S. and International teams to execute lifecycle programs that are globally consistent and locally adaptable within regulatory requirements, • Continuously optimize lifecycle programs based on performance insights, business priorities, and customer behavior, • Execute lifecycle campaigns within Salesforce Marketing Cloud (SFMC), including audience creation, journey configuration, QA, and deployment, leveraging IT-defined data models and platform frameworks, • Apply approved segmentation and personalization logic using available first- and third-party data sources, • Build and manage campaign setup, scheduling, and execution in a timely, detail-oriented manner; troubleshoot campaign issues, driving continuous improvement in CRM capabilities, • This role operates within established platform configurations and does not own system administration, data engineering, or platform infrastructure., • Partner closely with Omnichannel Operations Leads to execute against defined journey strategies and campaign sequencing, • Collaborate with Advanced Analytics and Data Strategy to apply segmentation, targeting, and personalization approaches, • Partner with IT and Data teams to ensure campaign readiness, data availability, and platform reliability, • Serve as a key liaison with external agencies and vendors supporting CRM execution, • Troubleshoot campaign-level issues (e.g., audience logic, journey behavior, delivery performance) and partner with IT on system-level root cause resolution, • Execute test-and-learn plans, including A/B and multivariate testing, • Optimize channel performance, including cadence, frequency, and engagement, • Execute campaigns in alignment with compliance, consent, and regulatory requirements (e.g., HIPAA, GDPR, OneTrust frameworks), • Maintain campaign documentation, QA processes, and audit readiness, • Leverage and contribute to standardized templates, modular assets, and reusable lifecycle frameworks, • Ensure campaigns align with omnichannel plans and cross-channel coordination Performance, Measurement & Enablement • Track and report on lifecycle performance metrics (engagement, conversion, retention, deliverability), • Partner with Advanced Analytics & Data Strategy to connect campaign performance to business outcomes, • Provide insights and recommendations to improve lifecycle execution and effectiveness, • Execute foundational lifecycle journeys (onboarding, engagement, reactivation) across priority brands, • Establish consistent, high-quality campaign execution processes within SFMC aligned to IT governance, • Implement structured testing and optimization roadmap, • Enable standardized lifecycle templates and workflows across teams, • Demonstrate measurable improvements in engagement, conversion, and retention, • 5+ years in CRM, lifecycle marketing, or digital marketing in a complex or regulated environment, • Hands-on experience executing campaigns in Salesforce Marketing Cloud or similar platforms, • Experience translating journey strategies into activated campaigns, • Strong understanding of customer lifecycle and multi-channel orchestration, • Experience working cross-functionally with marketing, analytics, and technology teams, • Experience in biopharma, healthcare, or regulated industries, • Familiarity with Salesforce Data Cloud, Marketing Cloud Personalization, • Working knowledge of SQL, AMPscript, or similar tools (for campaign execution, not engineering), • Experience supporting global lifecycle programs, • Exposure to consent, preference management, and privacy frameworks #LI-SS1 #LI-Hybrid U.S. Pay Range $142,800.00 - $193,200.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview Alnylam isseekinga deeply technical and strategic leader to serve as Senior Director, Research & Early Development (ReDev) Technology. This role owns the domain-specific scientific systems architecture, computational platforms, and AI-enabled digital capabilities supporting Target/BiomarkerDiscovery, RNAi Platform & Delivery, Screening, Lead Optimization, DMPK,Bioanalytics, Investigative Sciences, and Non-Clinical Safety. This is a strategic technology leadership role that also requires meaningful architectural depth. The Senior Director must partner closely with Research & Early Development leaders at all levels while actively guiding domain system architecture, integration patterns, modern data design, AI-enabled workflow modernization, secure scientific computing environments, and multi-omics/imagingdata integration. The role requires familiarity with large-scale human genetics and cohort datasets (e.g., UK Biobank,FinnGen,NASHBio) and the ability to design systems that enable their effectiveutilizationfor target discovery, validation, and translational research. The Senior Director will serve as the IT representative to the Research & Early Development Leadership Team, contributing to strategic discussions and ensuring digital priorities are tightly alignedwith scientific and portfolioobjectives. The role also requires close collaboration with Clinical Development and CMC organizations to ensure discovery and preclinical digital capabilities are aligned with downstream clinical, manufacturing, and regulatory requirements - enabling seamless lifecycle data continuity from target discovery through clinical development and CMC readiness. Shared lab execution platforms (e.g., ELN, LIMS) are owned by the Lab-to-Product Platform & Operations organization. Enterprise data engineering and centralized AI platforms are owned by the Enterprise Data & AI organization. This role partners closely with both to ensureReDevdomain systems are integrated, AI-ready, and aligned with enterprise standards. This hybrid role is based in Cambridge, MA with regular engagement at our Cambridge headquarters. Key Responsibilities Own theReDevDomain Architecture & Application Strategy • Define and govern the technical architecture across discovery and preclinical domain systems, • Lead lifecycle management of applications supporting:Molecular design and modeling; RNAi delivery and screening platforms;Digital pathology and imaging systems;DMPK, bioanalytics, and nonclinical safety;Omics, spatial omics, proteomics, and high-throughput platforms, • Enable effective integration and analysis of large-scale human genetics and cohort datasets (e.g., UK Biobank,FinnGen,NASHBio), • Partner with Enterprise Data & AI to design domain data flows into Alnylam's Snowflake-based enterprise data platform, • Define domain data requirements for genomics, proteomics, spatial omics, and imaging datasets, • Enable structured data products for human genetics and translational research, • Collaborate on metadata alignment, ontology mapping, and cross-cohort harmonization, • Partner with Enterprise Data & AI to design and operationalize AI-enabled workflows across discovery and preclinical domains, • Apply generative AI to support hypothesis generation, target identification, and multi-omics interpretation, • Architect agentic AI systems capable of orchestrating cross-dataset analyses (e.g., cohort genetics + proteomics + imaging), • Ensure AI capabilities are embedded into production scientific workflows, • Design andoperateTrusted Research Environments (TREs) to support secure analysis of sensitive human genetics and cohort data, • Enable controlled-access environments for datasets such as UK Biobank,FinnGen, andNASHBio, • Ensure compliance with privacy, governance, and regulatory standards, • Act as primary IT representative to the Research & Early Development Leadership Team, • Contribute to portfolio and target strategy discussions with a technology and data perspective, • Translate scientific strategy into scalable digital and AI-enabled architecture, • Represent IT in cross-functional and executive leadership forums, • Partner with Clinical and CMC technology leaders to ensure discovery and preclinical systems enable translational continuity, biomarker integration, clinical readiness, and downstream manufacturing alignment, • Contribute to cross-functional lifecycle architecture discussions spanningReDev, Clinical, and CMC Qualifications • 15+ years of progressive IT leadership supporting drug discovery and preclinical development, • Demonstrated architectural depth across complex scientific systems, • Proven ability to partner effectively with senior scientific stakeholders, • Experienceoperatingwithin senior leadership forums (e.g., R&D Leadership Teams) withdemonstratedexecutive presence, • Familiarity with large-scale population and cohort datasets such as:UK Biobank, FinnGen, NASHBio, • Demonstrated understanding of how these datasets areutilizedfor Target discovery and validation, Rare variant association, Translational research, • Experience supporting or integrating:Genomics and variant datasets, Spatial omics platforms, Proteomics datasets, Imaging-genomics analyses, • Deepexpertisein modern data engineering concepts:ELT/ETL patterns, Lake/lakehousearchitectures, API-first integration, Cloud-native data platforms, • Experience integrating domain scientific systems with enterprise data platforms (e.g., Snowflake) in partnership with centralized teams, • Advanced SQL and Pythonproficiencywith production-quality engineering standards, • Demonstrated practical experience applying both generative AI and agentic AI in scientific or R&D environments, • Experience operationalizing AI within production discovery workflows, • Hands-on experience designing and implementing Trusted Research Environments (TREs), • Strong understanding of responsible AI and secure scientific computing PreferredQualifications • Experience with: Digital Pathology & Imaging: HALO, HALO Link, Patholytix, Visiopharm;Non-Clinical Safety & DMPK: SEND environments, Phoenix (WinNonlin);Bioanalytics Platforms: Benchling, Sapio;Omics & Workflow Engines: Paradigm4, DNAnexus, AWS HealthOmics, Nextflow;High-Content Imaging: Signals Image Artist, • Experience in RNAi, oligonucleotide, or gene-modality platforms strongly preferred #LI-Hybrid #LI-LN1 U.S. Pay Range $226,800.00 - $306,800.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Senior Manager, Medical Research - Value & Evidence Strategy, Medical Affairs Overview Medical Research designs and drives the operational strategy of medical affairs studies in order to generate robust real-world evidence that provides further insight on disease diagnosis and utilization, safety and clinical effectiveness of approved treatments. The Senior Manager, Medical Research plays a key role in driving the generation of highquality realworld evidence to support the clinical and scientific value of Alnylam's therapies. This role provides strategic and operational leadership for global, regional and local medical affairs research initiatives, including observational studies, collaborative research, Phase IV studies, and registries. The Senior Manager serves as a central point of coordination across crossfunctional teams and external partners, ensuring rigorous execution, inspection readiness, and compliance with global regulatory and quality standards. The role collaborates closely with Medical Affairs, HEOR, Regulatory, Safety, Legal, QA, and external investigators, vendors, and CROs to deliver impactful evidence aligned with business and scientific objectives. Key Responsibilities • Lead operational planning, execution, and oversight of medical affairs research initiatives including Alnylamsponsored studies and collaborative research initiatives, • Provide oversight and strategic direction to CROs and vendors, to ensure performance, quality, and budget adherence, • Work, either directly with the CRO, or as part of the internal team to contribute to the development of program-specific plans and study documents, e.g. protocol, informed consent forms, training materials, CRFs, manuals., • Review and maintain study specific plans generated by CRO, • Ensure inspection readiness and compliance with applicable ICH/GPP standards, internal SOPs, and global regulatory requirements, • Partner closely with QA, GPSRM, Legal, and Compliance to support audits, inspections, and continuous process improvement, • Provide organizational and project support by working directly with cross-functional individuals and teams to coordinate and execute activities related to key medical affairs studies, • Coordinate development of agendas and maintain oversight of action items from program team (internal) and vendor meetings to drive execution of key initiatives and facilitate decision-making, • Management of study budgets, including annual budget planning Qualifications • BA/BS in life sciences or related field required; advanced degree preferred., • Proven experience in pharmaceutical/biotech industry, prior experience in Clinical Operations and/or Medical Affairs managing GCP/GPP studies., • Strong knowledge of ICH/GCP, regulatory guidelines/directives, and drug development and clinical research processes, • Experience managing CROs and vendors across multiple studies and geographies, • Must be able to actively manage and track many complex projects in parallel, managing the actions of many people toward shared outcomes, • Excellent communication skills and relationship building capabilities, • Strong team player that has a customer service approach and is solution oriented, • Attention to detail and the ability to work independently, within a multi-disciplinary team, as well as with external partners and vendors, • Clear alignment with Alnylam Core Values #LI-AB1 #LI-Hybrid U.S. Pay Range $144,500.00 - $195,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview: Reporting to the Senior Director, Access and Reimbursement, the National Director, Site of Care will optimize access to Alnylam products through the development of strategic engagement tactics and opportunities with key Alternate Site of Care accounts. This role leads a team of Strategic Account Leads who are assigned account management initiatives and strategies. This position requires a professional who can leverage their technical expertise and experience to meet Alnylam's site of care strategy goals that builds the capacity to support patient access to our therapies and supports an enhanced experience for patients and health care providers. A key component of this role is the ability to establish the strategy, build the processes and identify opportunities that allow the site of care team to deepen customer relationships and manage the agreed upon deliverables at targeted strategic accounts. As such, extensive knowledge of 'buy and bill' products and prior experience with high-touch, specialty products is essential. The successful candidate must be passionate about science and deeply motivated by the quest of delivering seamless patient access to our therapies with the long-term success of the company in mind. They will work collaboratively with both internal and external stakeholders to execute strategic imperatives. Key Responsibilities: • Work with the Senior Director and Market Access Leadership to establish the comprehensive account strategy for key accounts, informed by insights from internal and external stakeholders, to bring the best of Alnylam to the customer, • Strong partnership with internal legal and contracting partners to evaluate strategies and opportunities and in supporting the execution of individual agreements., • Collaborate with Commercial Leadership (Sales, Marketing, Market Access, Distribution and Operations) colleagues to ensure adequate Voice of the Customer in addition to own insights to influence strategic planning across stakeholders that encourages innovation and improves service delivery, • Work with the Senior Director to identify program objectives, identify future targets and KPIs for target accounts that are aligned with organizational and customer priorities, • Analyze and synthesize information from multiple sources to identify and prioritize business opportunities and potential risk across the accounts by applying relevant frameworks and analytical methods, • Lead the execution of the comprehensive account strategy across the Strategic Account Lead team with Key Accounts, • Works closely with internal Alnylam partners to identify enhancements for engagement with key accounts (Ways of Working) across Alnylam, key conference identification, updated language in RFPs and MSAs and resource gaps to fulfill for the team to effectively engage and execute on strategic initiatives., • Anticipate and communicate likely or transpiring market and customer developments, identify third party influence factors and shape the account engagement strategy accordingly, • Coach the team in creating and fostering strong relationships and perception of Alnylam as a strategic partner with senior business stakeholders (C- and D-Suite) in target accounts, including PE-backed groups, to deliver on strategic goals for Alnylam's products across the company portfolio, • Ensure consistent, best-in-class site of care strategic account management practices across all customer engagements, • Negotiate, manage and pull-through agreements that incorporate solutions to strengthen partnerships between Alnylam and strategic accounts, • Manage the individual responsibility for and oversee the team's ongoing contractual agreements and relationships with strategic accounts to strengthen partnerships and unlock new business opportunities, • Lead the team in the Development, execution and oversee quarterly business reviews, strategic planning sessions, and long-term roadmap development with key accounts Qualifications: • Bachelor's degree required, emphasis in business management; Master's degree preferred, • Minimum 10 years' of experience in the life sciences environment, • Minimum 5 years' previous account management experience with health systems or alternate sites of care C- and D-Suite or payors, • Experience leading a team of account managers, • High level of confidence, exceptional written and oral communication skills and executive presence required to engage with a C-Suite audience, • Strong knowledge of the US payer landscape, value-based care and outcome-based models, • Demonstrated ability to successfully mobilize cross-functional partners, including interpersonal skills to foster collaboration and succeed by leading without direct authority, • Deep understanding of both medical benefit and pharmacy benefit, • Strong analytical skills, able to synthesize multi-source information for strategic planning and ability to think critically, challenge conclusions and underlying assumptions, • Self-starter who is enthusiastic about rare disease and Alnylam's core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, • Highly proficient in Microsoft Office Suite, • Ability to travel up to 50%, • Should live near a mid-sized to major airport #LI-ST1 #LI-Remote U.S. Pay Range $210,000.00 - $284,100.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview The Associate Director, Patient Advocacy and Engagement, Pipeline Programs will play a critical role in driving patient-centric strategies and strengthening relationships with patient advocacy organizations. Reporting to theSr. Director, Global Patient Advocacy Rare and Pipeline. The role will ensure alignment of patient advocacy effortswith selected clinical development programs to enable patient centred trial development and delivery. The role will require a dynamic leader with strong experience in patient advocacy and interpersonal skills. This position is hybrid onsite 2 days a week, primarily located Alnylam's Head Office in Cambridge Massachussets. Key Responsibilities • Develop and execute the patient advocacy strategy for programs within the pipeline portfolio, ensuring alignment with the medical and clinical program strategy., • Partner with internal stakeholders, including Development, Medical Affairs, Commercial, Market Access, and Public Affairs teams, to ensure a unified approach to patient advocacy efforts., • Develop strategic collaborations between internal and external stakeholders in line with mutual goals to enhance care for patients., • Enable patient input and engagement into regulatory and market access submissions., • Lead the implementation of advocacy programs that are culturally and regionally appropriate, ensuring a positive impact at the national and local levels., • Support Alnylam's patient-focused culture collaborating closely with legal, compliance, and data privacy colleagues to ensure strict adherence to local codes and company policies., • Serve as the primary point of contact for international, national, regional and local patient advocacy groups, fostering trusted relationships that support mutual goals., • Identify and address unmet patient needs by facilitating programs, initiatives, and collaborations that enhance disease awareness, patient education, and access to treatment., • Enable patient and caregiver understanding of clinical research by developing and delivering education initiatives that improve awareness of Alnylam-sponsored clinical trials and build knowledge of RNA interference (RNAi), supporting informed and meaningful engagement in research., • Champion diversity, equity, and inclusion in clinical research by collaborating with patient advocacy groups to increase awareness, build trust, and support participation of underrepresented patient populations in clinical studies.Develop initiatives to enhance disease awareness and improve time to diagnosis, as well as educate the patient community so that they are empowered to actively engage with their healthcare provider in the management of their disease., • Represent the organization at patient advocacy events, including conferences, meetings, and community forums, to strengthen external relationships., • Partner closely with development functions, including Clinical Operations, Clinical Research, VEST, and related R&D teams, to ensure patient perspectives and advocacy insights are incorporated across the clinical development lifecycle., • Collaborate with clinical and research stakeholders to inform trial design, feasibility, and execution by integrating patient and caregiver insights, with a focus on patient experience, access, and equitable participation., • Work cross-functionally with Market Access, HEOR, and evidence-generation teams to ensure patient needs and community perspectives are reflected in value frameworks, evidence strategies, and access considerations., • Facilitate bidirectional engagement between patient advocacy organizations and internal development stakeholders to support shared understanding, education, and alignment on disease burden, unmet needs, and research priorities., • Enhance internal understanding of patients, caregivers, and affected communities across R&D and enterprise stakeholders to support strategic decision-making that reflects lived experience and patient-centered outcomes., • Provide patient advocacy input and support for cross-functional initiatives and programs as required, including disease education, research enablement, and strategic planning efforts., • Lead the development of patient education materials, advocacy resources, and engagement plans in partnership with internal and external stakeholders., • Monitor and evaluate the impact of patient advocacy initiatives, ensuring continuous improvement and alignment with organizational goals., • Ensure all patient advocacy activities comply with regulatory, legal, and ethical standards. Qualifications Education • Advanced degree in life sciences, public health, or a related field preferred (PhD, PharmD, MD, or MBA a plus)., • Ability to travel approximately 30% of the time. Experience: • Solid experience in biotech and pharmaceutical industry., • 3+ years of experience in patient advocacy, preferably in the biopharmaceutical industry., • Proven expertise in rare diseases or conditions relevant to primary hyperoxaluria and acute hepatic porphyria is strongly preferred. Renal and cardiac experience would be welcomed., • Experience leading high-impact patient engagement programs at the national or regional level. Skills and Competencies: • Exceptional relationship-building skills with the ability to influence and collaborate across internal and external stakeholders., • Strong understanding of the patient advocacy landscape, particularly in rare diseases., • Strategic mindset with the ability to translate complex strategies into actionable plans., • Proven ability to manage budgets and thrive within compliance operations frame works., • Excellent communication, presentation, and organizational skills. Key Success Factors: • Passionate advocate for patients and caregivers, demonstrating empathy and a commitment to improving the patient experience., • Collaborative team player with a proactive, solutions-oriented mindset., • Strong business acumen, with the ability to balance patient needs with organizational goals., • Ability to thrive in a fast-paced, network operating or matrix environment; able to prioritize high-impact projects; works with a sense of purpose and able to roll up their sleeves and execute. U.S. Pay Range $179,200.00 - $242,400.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview: At Alnylam Pharmaceuticals, we are leading the RNAi Revolution, developing innovative therapies that transform the lives of patients with rare and prevalent diseases. As a Federal Account Director, you will play a key role in executing our U.S. federal market access strategy, with a primary focus on assigned Department of Veterans Affairs (VA) VISN and VA Hospital accounts, as well as supporting Department of Defense (DoD) ecosystems where applicable. This position requires expertise in the federal healthcare landscape, including VA/DoD reimbursement dynamics, formulary processes, Criteria for Use (CFU), utilization management, and stakeholder engagement, particularly for therapies requiring administration by healthcare professionals under the medical benefit. You will focus on optimizing access and appropriate utilization of Alnylam's HCP-administered products by ensuring compliant application of the VA National Formulary and CFU at your assigned accounts. In collaboration with cross-functional partners, you will educate site administrators, department chairs, and clinical influencers on the value proposition of Alnylam products for Veterans and service members. You will also support cross-functional pull-through efforts, contribute to federal access strategies, and provide insights to inform broader team initiatives. This role demands agility to navigate evolving policies, market conditions, and federal requirements while identifying opportunities to enhance product utilization. You will collaborate with internal teams, including sales, medical affairs, health economics, and strategic accounts, to align with Alnylam's commercial objectives and mission to deliver groundbreaking RNAi therapeutics to patients in federal systems. This is a field-based remote position requiring up to 50-70% travel and reports to the Senior Director, Federal Accounts. Key Responsibilities: • Execute federal access strategies within assigned VISN and VA Hospital accounts to optimize patient access and appropriate utilization of Alnylam's portfolio., • Ensure compliant application of the VA National Formulary and Criteria for Use (CFU) for Alnylam products at the site level., • Partner with the cross-functional team to ensure that critical education is delivered to key stakeholders including site administrators, department chairs, and healthcare professionals. This education includes: disease-state education, clinical information, as well as administration requirements of Alnylam's therapies., • Analyze account-specific data, trends, and utilization metrics to identify opportunities for enhanced pull-through and appropriate use., • Collaborate with field sales, Regional Business Directors, and cross-functional partners to implement pull-through tactics and support sales performance in federal accounts., • Contribute to the development and execution of account plans, sharing insights and best practices with the federal team., • Support federal market development initiatives, including engagement with organizations such as the Association of Military Surgeons of the United States (AMSUS)., • Provide federal payer and account insights to market access, HEOR, patient services, and leadership teams to inform strategies and address gaps. Accountabilities: • Build and maintain multi-level relationships within assigned federal accounts (VISNs, VA Hospitals, and related DoD entities), positioning Alnylam as a trusted partner for HCP-administered innovations benefiting Veterans and service members., • Navigate federal provider structures to engage key decision-makers, influencers, and clinical stakeholders, fostering long-term partnerships that support Alnylam's current products and pipeline., • Prioritize account activities to ensure consistent, compliant implementation of national formulary and CFU, addressing site-specific needs for medical benefit therapies., • Collaborate with internal experts (e.g., Medical Affairs, national contracting, and policy teams) to support access positioning and medical policy alignment., • Deliver tailored education on the value proposition of Alnylam products, emphasizing benefits for patient populations served in federal settings., • Review sales, utilization, and trend data to uncover pull-through opportunities, developing tactics aligned with team KPIs., • Work with field sales teams to execute pull-through plans, providing training on federal payer dynamics, formulary processes, CFU requirements, and reimbursement for HCP-administered therapies., • Maintain compliance with all legal, regulatory, and company policies in stakeholder interactions and program execution., • Contribute to team knowledge sharing by documenting best practices, participating in training, and supporting pilot programs or initiatives. Qualifications: • Bachelor's degree required (business or science preferred); advanced degree (e.g., MBA, PharmD) a plus., • Minimum 7+ years of pharmaceutical/biotech experience, with at least 3 years in account management, payer access, or related roles; direct experience in VA/DoD or federal channels preferred., • Proven track record in managing complex accounts, influencing stakeholders, and driving results in healthcare environments., • In-depth knowledge of federal healthcare systems, including VA National Formulary, Criteria for Use (CFU), VISN dynamics, aprocurement process for HCP-administered therapies, medical benefit coverage, utilization management, site-of-care strategies, and reimbursement pathways., • Strong analytical skills to interpret data, identify opportunities, and develop actionable account plans., • Consultative approach to stakeholder engagement, with expertise in value communication and educational program delivery., • Understanding of payer economics, utilization management, and evolving U.S. policies impacting federal systems., • Comprehensive knowledge of pharmaceutical operations, including prescribing, regulations, supply chain, managed care, sales, and compliance., • Excellent communication, presentation, and relationship-building skills; ability to collaborate effectively in cross-functional teams. #LI-ST1 #LI-Remote U.S. Pay Range $211,500.00 - $286,100.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

___ Job Type Full-time Description The Opportunity Fenway Health seeks an exceptional Chief Development Officer (CDO) to drive a bold, modern advancement strategy for one of the nation's most influential LGBTQIA+ healthcare and equity. As Fenway enters a new era after more than fifty years of national leadership in LGBTQIA+ primary care, HIV services, research, and advocacy, this role offers a rare opportunity to lead transformational growth at a defining moment. As a key member of the executive team, the CDO will architect and execute a comprehensive fundraising strategy-advancing major gifts, individual giving, corporate and foundation partnerships, and government support. The ideal candidate is a sophisticated fundraiser who understands donor motivations, emerging giving vehicles, and how to convert organizational impact into compelling philanthropic investments. Reporting directly to the CEO and partnering closely with the EVP of External Affairs, this leader will inspire a committed team, mobilize an engaged Board, and deepen relationships across a passionate donor community. They will strengthen Fenway's visibility, credibility, and philanthropic momentum to expand high-quality, affirming care for LGBTQIA+ people and underserved populations. Candidates should bring a strong track record in major gifts, board partnership, and preparing organizations for transformational fundraising initiatives-including campaign readiness and case development. The ideal executive is an equity-centered, LGBTQIA+ culturally fluent leader with exceptional relationship-building, communication, and management skills. They will embed racial equity and social justice across all development practices, ensuring fundraising both advances and reflects Fenway's mission and values. Representative Duties Strategy & Leadership • Strategic Fundraising Leadership: Lead a comprehensive, multi-year fundraising strategy aligned with the organization's mission, growth trajectory, and capital ambitions. Set clear annual and long-term revenue targets across all funding streams and identify new philanthropic opportunities and innovative funding models. Apply an intersectional equity lens across all development strategies, donor engagement, and stewardship practices., • Strategy Execution & Accountability: Translate strategy into actionable development plans, timelines, and accountability structures that drive consistent progress toward revenue goals., • Strategic Visioning: Build and grow an individual giving program from design through execution, including donor cultivation, solicitation, and stewardship. Re-envision special events and engagement strategies to inspire sustained donor commitment in a shifting philanthropic and market environment., • Major Donor Portfolio: Bring and actively cultivate a portfolio of high-capacity philanthropic relationships while expanding the pipeline and advancing major prospects capable of seven to nine-figure investments., • Donor Relationship Management: Serve as a primary relationship manager for key donors and partners, building trusted relationships that deepen long-term engagement, philanthropic investment, and stewardship. Design inclusive donor engagement strategies that authentically cultivate and steward supporters across racial and ethnic identities, sexual orientations, gender identities, and generations, including younger and emerging donors., • CEO Partnership: Work closely with the CEO to advance high-level fundraising priorities, major gift opportunities, and key donor engagements., • Board Engagement & Activation: Equip and activate the Board of Directors as philanthropic donors themselves as well as ambassadors by identifying opportunities within their networks, preparing them for donor conversations, and supporting their meaningful participation in fundraising efforts., • Development Infrastructure: Build and strengthen the systems, processes, and tools that improve donor engagement, increase philanthropic conversion, and support sustained fundraising growth., • Analytics & Performance Measurement: Leverage data to inform strategy, forecast revenue, and monitor pipeline performance through clearly defined key performance indicators (KPIs)., • Cross-Functional Collaboration: Partner across executive leadership, communications/marketing, clinical, programming, finance, and operations to ensure fundraising strategies align with organizational priorities and programmatic opportunities., • Adheres to all agency and departmental policies and procedures, • Participates in quality assessment and improvement activities as requested, • Adheres to the highest principles of patient, client, and donor confidentiality, • Adheres to established safety policies, procedures and precautions; identifies potential or actual unsafe situations in the environment and takes measures to rectify the situation, • Attends all required meetings, in-services and professional trainings, • Maintains professional competence necessary to perform job responsibilities; maintains and provides agency with records of continuing education activities, • 10+ years of progressive nonprofit fundraising leadership experience, including at least 5-7 years at the executive-level, • Minimum 5 years in healthcare and/or, nonprofit organizations (including FQHCs), • Demonstrated success securing seven- and eight-figure philanthropic investments., • Proven success in senior development roles, including supervising and leading midsized teams., • Demonstrated ability to engage individuals and communities around a shared mission and build a strong culture of philanthropy., • Strong track record designing and executing diverse fundraising strategies, including major gifts, planned giving, peer-to-peer giving, events, and donor cultivation., • Demonstrated success securing principal and transformational gifts., • Experience successfully engaging a diverse donor base, including communities historically underrepresented in philanthropy., • Demonstrated commitment to fostering inclusive, equitable, and supportive workplace environments., • Experience with corporate and foundation fundraising with an established network of corporate relationships., • Ability to set ambitious yet achievable goals, develop clear plans and metrics, and adapt strategies as needed., • Strong project management skills, with the ability to prioritize and lead complex initiatives to completion., • Excellent written, verbal, and interpersonal communication skills., • Solid understanding of event strategy, execution, and cost management., • Experience in healthcare, research, and/or LGBTQIA+- serving organizations preferred., • Enthusiasm and passion for Fenway Health's mission, • Impeccable integrity with a strong commitment to professionalism and promoting well-being of staff, • Strong interpersonal skills; an effective relationship builder, • LGBTQIA+ identified persons, people of color, and others from historically underrepresented communities are strongly encouraged to apply Physical Requirements: • Ability to meet the following physical requirements with or without reasonable accommodations:, • Sit at a computer station for extended periods of time, • Ability to keyboard for extended periods of time Supervisory Responsibilities Supervises Development and Fundraising Team We offer competitive salaries, and for those who qualify, an excellent benefits package; including comprehensive medical and dental insurance plans, and a retirement plan with employer match. We also provide 12 paid holidays, paid vacation, and more. LGBTQIA+ identified persons, Black, Indigenous, and other people of color (BIPOC), and individuals from other historically underrepresented communities are strongly encouraged to apply. Salary Description $190,000 - $305,000 /year

< Overview The Director, Development Strategy & Operations role will be focused on delivering the near- and long-term objectives of the R&D Leadership Team as Alnylam delivers the next wave of transformational medicines. Reporting to the Executive Director, Development Strategy, Operations, & Portfolio, this role will have broad responsibility for strategic planning and operational delivery within Clinical Development. This individual will drive high-priority projects for the Development organization, facilitate effective prioritization and decision-making, and serve as a thought-partner and executor for senior leaders in the Clinical Development organization (e.g., Pipeline Delivery & Clinical Operations, Clinical Research, Quantitative Sciences). As a partner to senior leaders Clinical Development, this role requires a highly resourceful person with strong emotional intelligence, self-motivation, proven cross-functional collaboration abilities, and the ability to manage ambiguity and thrive in a fast-paced environment. Key Responsibilities • Enable a strong connection between the week-to-week operations of the Development and the long-term enterprise strategic roadmap, • Support R&D senior leaders in identifying, scoping, organizing, leading execution, and monitoring progress on priority initiatives (e.g., accelerating cycle times and speed to market), • Contribute to above-asset and portfolio-wide analyses and initiatives such as disease area strategies, portfolio scenario planning and portfolio prioritization, strategic resource planning and management, etc., • Drive corporate planning deliverables (annual goal setting, annual investment planning, long-range planning) via thought-partnership with senior leaders, delivering analyses, and running a tight process in coordination with other expertise areas (e.g., Finance), • Facilitate effective decision-making and follow-through on actions, e.g., for pipeline Governance meetings and priority initiatives steering committees, • Be a trusted thought-partner and problem-solving partner with senior R&D Leaders and the Executive Director, R&D Strategy, Operations, & Portfolio, • Prepare analyses, gather and structure data, structure ambiguous problems, and distill into executive-level communications Qualifications • Bachelor's degree in scientific or business discipline; MBA or PhD preferred, • 10+ years of experience, 7 of which in the biotechnology, pharmaceutical, and/or management consulting or professional services, with experience in Clinical Development and R&D, • Experience working on high-visibility projects with frequent engagement with senior stakeholders, • Excellent problem solving and execution skills, • Ability to manage ambiguity and multitask, • Strong project management and matrix working skills, • Ability to build trust and effective working relationships with colleagues across functional groups and levels of seniority (including senior executives), • Strong written and oral communication skills, • Ability to influence without authority, • Energized by working in a highly entrepreneurial biotech environment, • Intellectual curiosity, adaptability, and desire to learn and continually build skills U.S. Pay Range $208,300.00 - $281,800.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

JOB TITLE: Medical Director, Oncology REPORTS TO: Senior Vice President, Head of Clinical Development DATE PREPARED: March 12, 2026 JOB SUMMARY: AVEO Oncology is seeking a highly skilled and experienced Medical Director to join our dynamic team. The successful candidate will have a strong background in oncology, specifically renal cancer, previous experience in early phase development strongly preferred; and a proven track record in managing global clinical trials. This role is pivotal in driving the clinical development of our oncology pipeline and ensuring the successful execution of our clinical programs. PRINCIPAL DUTIES: 1. Leadership skills: • Provide medical and scientific leadership in the design, execution, and interpretation of Phase I clinical studies., • Collaborate with cross-functional teams, including clinical operations, regulatory affairs, and biostatistics, to ensure alignment on clinical strategy and study design., • Ensure clinical trials are conducted in compliance with applicable regulations, guidelines, and company policies., • Oversee clinical aspects of global clinical studies, ensuring consistency and quality across all regions., • Lead interactions with key opinion leaders to align clinical development plans. 2. Medical Monitoring and Safety Oversight: • Serve as the medical monitor for assigned clinical trials, providing ongoing medical oversight and guidance, addressing any issues that arise to ensure timely completion and high-quality data., • Assess and interpret clinical trial data, ensuring accuracy and completeness of safety and efficacy information., • Collaborate with pharmacovigilance teams to monitor and manage adverse events and other safety concerns. 3. Data Analysis and Reporting: • Participate in data analysis, interpretation, and presentation of clinical study results to internal and external stakeholders., • Contribute to the preparation of clinical study reports, regulatory submissions, and scientific publications., • Present clinical data at scientific conferences and advisory boards. 4. Stakeholder Engagement: • Develop and maintain strong relationships with key opinion leaders, investigators, and clinical trial sites., • Represent AVEO Oncology at scientific meetings, conferences, and industry events. REQUIRED QUALIFICATIONS/EXPERIENCE (BASIC QUALIFICATIONS): Education: • Medical Doctor (MD) degree is required. Experience: • Minimum of 3-5 years of experience in oncology clinical development, familiarity with Phase I and phase II clinical studies is required., • Demonstrated experience in managing global clinical trials and navigating international regulatory environments. Skills: • Strong clinical and scientific acumen in oncology., • Excellent leadership, communication, and interpersonal skills., • Proven ability to work effectively in a cross-functional, global team environment., • Strong analytical and problem-solving skills with keen attention to detail. Preferred Qualifications: • Experience working within a biotechnology or pharmaceutical company., • Demonstrated ability to drive clinical development strategies and make data-driven decisions., • Prior experience interacting with global regulatory agencies and key opinion leaders., • Experience in renal oncology clinical trials. About AVEO AVEO is a commercial-stage, oncology-focused biopharmaceutical company committed to delivering medicines that provide a better life for patients with cancer. AVEO currently markets FOTIVDA (tivozanib) in the U.S. for the treatment of adult patients with relapsed or refractory renal cell carcinoma (RCC) following two or more prior systemic therapies. AVEO continues to develop FOTIVDA in immuno-oncology combinations in RCC and other indications and has several other investigational programs in clinical development. AVEO is committed to creating an environment of diversity, equity and inclusion to diversify representation within the Company. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

< Overview We are seeking an experienced professional for the role of Senior Manager, Clinical Supply Chain In this position you will play a critical role in ensuring seamless execution of clinical supply operations across multiple programs. You will hold program-level ownership and trial-level leadership for clinical supply delivery, ensuring reliable, compliant, and uninterrupted supply of clinical trial material to sites worldwide, in support of Alnylam's growing pipeline and patient needs. This role provides both leadership and hands-on execution. You will support CSC team members in operational delivery while also serving as a senior individual contributor for complex or large scale studies when needed. The Senior Manager will collaborate closely with senior CSC leaders to maintain robust, compliant and effective operational processes. You will partner crossfunctionally with Quality Assurance, Clinical Operations, Program Management, and Regulatory Affairs, and external CMOs, to drive successful trial execution in a dynamic environment. Strong, proactive communication is essential, as the role interfaces regularly with internal stakeholders and external partners. Overall, you will be responsible for supporting CSC team members, overseeing supply execution, identifying and mitigating risks, and ensuring clinical supply program objectives are met efficiently throughout the lifecycle of assigned studies and programs. This position is well-suited for professionals with experience supporting large, global clinical studies or multiple concurrent trials in a fast-paced, cross-functional setting. You will focus on overseeing programs, protocols, and CSC team members as you manage the global supply of essential clinical materials, prioritize needs, and maintain operational excellence. Your ability to communicate clearly, collaborate effectively, and navigate complex operational challenges will be key to success. This position is hybrid and will be primarily located in the Alnylam Cambridge office. Key Responsibilities • Accountable and/or responsible for clinical supply related activities for assigned program(s) and/or protocol(s) including, but not limited to execution of supply strategy, IRT setup & management, packaging, labeling, distribution, returns, destruction, and study closeout., • Drive issue resolution across vendors and internal teams, balancing speed, quality, and compliance, • Identify, assess, and manage execution-related risks at the program and trial levels, • Provide program-specific insights, emerging risks, and execution details to Clinical Supply Chain Strategic Planners to ensure effective supply plan, • Support and mentor CSC team members as needed on operational execution of clinical supply activities, • Ensure all program goals and objectives are met on time & monitored across the course of the study, from a clinical supplies perspective (e.g. FSA, FPI, enrollment progress), • Support inspection readiness for assigned program(s) and/or protocol(s) and department processes., • Ensure current systems & procedures are aligned with current regulations & industry standards., • Responsible for program budget and long range budget planning for assigned programs., • Engage with CMO, CRO, & key suppliers that support systems, production & distribution., • People Management - direct and indirect Qualifications • B.Sc. in a scientific field or Supply Chain Management. Pharmacy degrees are encouraged to apply., • 6-8 years of direct Clinical Supply Chain experience globally, • Knowledge of end to end clinical supply chain with a focus on operational execution, • Proficient knowledge of various project management and process tools MS Office (e.g. Excel, Smartsheet, PowerPoint, Visio, Project), • Experienced working with & managing third-party CMO clinical supply operations., • Strong experience of - IRT/RTSM including development of specifications, , & understanding areas of limitations, risks, or gaps to mitigate, • Excellent communication, attention to detail, collaboration, ability to manage complex challenges, and influencing skills #LI-LJ1 #LI-Hybrid U.S. Pay Range $136,900.00 - $185,200.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Opportunity awaits those up to the challenge of developing transformative therapies across a broad range of debilitating diseases. Summary: Apellis is seeking a passionate and talented marketer for the role of Product Manager, US Professional Education (Prof Ed) on our Geographic Atrophy (GA) Marketing Team. It is an outstanding opportunity to make a significant impact for Eyecare Professionals (ECPs) and the company, supporting US marketing activities for the first therapy to be approved in advanced atrophic, age-related macular degeneration, or GA. This position will be a vital member of the GA brand team and will be supporting the highly compliant marketing activities that involve Key Opinion Leaders (KOLs) in promotional peer-to-peer (P2P) education. These channels will be a mix of live/virtual events but could also be via non-personal promotion (NPP) to drive disease state education and support the branded campaign. They will be deeply engaged with internal cross-functional partners, and external agencies and vendors, fostering collaboration and accountability. The Product Manager, US Professional Education will report to the Associate Director, US Marketing - Professional Education Lead. This role is hybrid and based in Waltham, MA, with an expectation of being in the office a minimum of two days per week. Roles and Responsibilities: Key Responsibilities Include: • Execute the vision for US Professional Education, in alignment with overall brand strategy, • Lead the development of Professional Education materials end-to-end, through the brief creation, content design, submission, review, and deployment process. Key assets include educational content creation, event promotional drivers, supplements, discussion guides, pre/post program surveys, etc., • Collaborate with internal and external partners in the creation of professional education content for speaker training, speaker programs and symposia use, • Execute operations for speaker programs and symposia including project management, speaker contracting, budget management, sunshine reporting, and program analysis, • Assist in the development and execution of trainings for KOL speakers including event management team, medical team and thought leader liaisons, • Liaise with cross-functional partners on the selection and use of KOL speakers, • Execution of advisory boards or other methods to better understand key business barriers facing the Ophthalmic Franchise, • Build and nurture strong, positive relationships with key partners across field teams, congress marketing, patient marketing, medical affairs, market access, business intelligence, commercial operations, IT, and compliance in order to ensure cross-functional integration, • Manage agency partners and other vendors to ensure seamless execution, • Ensure that all Professional Education processes, documents, and tactics are developed and implemented in accordance with Apellis corporate legal, regulatory, and compliance guidelines, • Draft needs assessment forms and track contracts, scopes of works, and master service agreements through the system for those events or meetings, collecting relevant information to close them out in the system once complete and ensuring correct honorarium is paid, • Efficiently and thoughtfully administer and manage the Professional Education budget Education, Registration & Certification: • BS/BA degree required Experience: • 3+ years of biotech/pharma experience, predominantly in marketing/professional education roles of increasing scope and responsibility, • Marketing background and experience in HCP marketing including peer-to-peer education, non-personal programming, advisory boards, speaker training, speaker programs, KOL management and agency management, • Ophthalmology experience preferred, • Experience launching new products or indications preferred Skills, Knowledge & Abilities: • Passion for understanding and championing the needs of people treating serious diseases, translating them into market-moving insights, • Ability to navigate and be successful in a fast-paced, results-driven environment, managing through ambiguity, • Strong understanding of clinical decision-making process, drivers and barriers of HCP behavior, and approach to educating to distinct segments and different customer types, • Ability to quickly digest scientific and clinical updates and translate into marketing tactics, • Commitment to collaboration and engagement, with a history of success leading in a matrix environment and with agency partners, • An entrepreneurial spirit coupled with the drive to embrace innovation and develop creative but well-reasoned solutions to business challenges, • Motivation to be a part of envisioning and building the infrastructure, systems, and tactics to ensure launch success, • Demonstrated integrity on the job, including an understanding of relevant rules and regulations, • Exceptional planning and project management skills, • Excellent written and verbal communication skills with the ability to influence across functions and varying levels of the organization, • Willing to travel domestically up to 30% of the time and attend events outside of business hours (e.g., occasional weekends and evenings) Travel Requirements: up to 30% travel Education: Bachelor's Degree Pay Information: Base salary for this role will consider multiple factors, including but not limited to, candidate qualifications, relevant expertise, specialized skills, and industry experience in complement-targeted therapies. The targeted base salary range for this position is $142,000-$213,000. This range represents the base salary only and reflects Apellis' commitment to competitive compensation within the biopharmaceutical industry. The final salary offered may vary based on individual qualifications, business needs, and current market conditions. Work Arrangement: Benefits and Perks: Apellis offers a comprehensive benefits package, including a 401(k) plan with company match, inclusive family building benefits, flexible time off, summer and winter shutdowns, paid family leave, disability and life insurance, and more! Visit ___ to learn more. Company Background: Apellis Pharmaceuticals, Inc. is a global biopharmaceutical company leading the way in complement science to develop life-changing therapies for some of the most challenging diseases patients face. We ushered in the first new class of complement medicine in 15 years and now have two C3-targeting medicines approved to treat four serious diseases. Breakthroughs for patients include the first-ever therapy for geographic atrophy, a leading cause of blindness, and the first treatment for patients 12 and older with C3G or primary IC-MPGN, two severe, rare kidney diseases. We believe we have only begun to unlock the potential of targeting C3 across many serious diseases. For more information, please visit . EEO Statement: Apellis is an equal opportunity employer and complies with all applicable federal, state and local fair employment practices laws. Apellis strictly prohibits and does not tolerate discrimination against employees, applicants or any other covered persons because of race, color, religion, creed, national origin or ancestry, ethnicity, sex (including pregnancy), gender (including gender nonconformity and status as a transgender or transsexual individual), age, physical or mental disability, citizenship, past, current or prospective service in the uniformed services, genetic information, marital status, AIDS/HIV status, smoker/nonsmoker, and occupational pneumoconiosis or any other characteristic protected under applicable federal, state or local law. For San Francisco postings: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Other Duties: Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.

< Overview The Associate Director is responsible for leading a team of Global Trial Leaders and Trial Managers within the Study Management Organization. The position is responsible for staff development and study oversight, and will work closely with the Director for input on project assignments, workload distribution, resourcing, and prioritization. The Associate Director directly influences trial objectives and ensures common operational issues/challenges are identified within and potentially across trials and programs and are addressed through operational risk mitigation, including proposals for alternative solutions. The Associate Director is also accountable for the operational execution of all trials within a program. Summary of Key Responsibilities Accountable for the delivery of the operational strategy in alignment with the Clinical Development Plan, ensuring alignment with the business goals and trial delivery objectives (including resourcing, budget, and change control) by partnering with CTWG and CDST on timeline creation. May Chair and/or support the Trial Leader in leading the CTWGfor the successful execution of assigned trial/s. • Define (for early development), or work with the Director to align on, the Operational Strategy for each trial in the program and gain governance endorsement on proposed plans, • Lead operational scenario planning and mitigate trial level risks that may impact timelines / budget., • Ensure appropriate timely and quality oversight, and appropriately escalate issues to the Director, Quality and functional leadership., • Ability to effectively communicate the operational strategy, and defend the operational plan and costs associated to CTWG, CDST, Director, leadership and at governance meetings as appropriate., • Lead and ensure inspection readiness for the trial/s, • Build knowledgeable and skilled team with competencies and capabilities to successfully set up and deliver clinical trials, • Promote strong collaboration across cross-functional teams, • Setting goals in alignment with company, program, and departmental goals, • Ensure staff training on procedures and systems associated with their roles, • Develop a team that consistently achieves strong results through nurturing individual growth, effectively managing performance, and providing guidance, • For early development programs, AD may represent Clinical Operations at CDST, • Interface with internal key stakeholders including, but not limited to; Finance, Program Management, Vendor Management, Safety, Accounting, Supply, Quality Assurance, Data Management, Statistics, Clinical Research, Commercial, Regulatory, Bio Analytical, Medical Affairs; which may include acting as a liaison between groups., • Lead or participate in process improvement activities at a trial and department level as needed, • Participate in preparation for, and conduct of, Health Authority Inspections and internal QA audits, • Ability to travel (expected annual average of 10% but flexibility to go over or below this as required). Qualifications • BS/ BA degree is required., • Minimum 8+ years of clinical research experience gained with a CRO, Biotech or Pharmaceutical Company working on Phase 1-4 global clinical trials., • 3-5 years leading end to end global clinical trials with experience in conducting Phase 3 registrational trials, • Experience in and knowledge of the pharmaceutical development process, • Excellent decision-making, analytical and strong financial management skills are essential to this position, • Ability to manage all aspects of execution of a clinical trial, • Must possess excellent leadership skills, proven ability to foster team productivity and cohesiveness and the ability to operate and execute with limited supervision, • Experience in leading without authority and in multifunctional matrixed and global environments, • Strong project planning/ management, communication (written and verbal) and presentation skills, • Minimum 2+ years prior line management experience or 3+ years matrixed leadership experience required, • Exceptional organizational skills and ability to deal with competing priorities, also strong reasoning and problem-solving ability., • Apply project management best practices to programs. Experience in novel clinical drug development., • Proficient with MS Office Suite (Excel, Word and PowerPoint) and MS Project. U.S. Pay Range $172,600.00 - $233,400.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Description: The Senior Manager, Business Operations serves as a strong cross-functional partner for financial and resourcing planning needs for Clinical Operations, as well direct support for CRO work order and contract modification processes. This role is responsible for reporting, analytics, project management, and coordination required to drive the business to efficient and effective financial and resource management processes. Summary of Key Responsibilities • Create accurate, transparent, and timely financial analyses to support Clinical Operations accruals; clearly articulate financial implications from variances between forecast and actuals and provide retrospective analysis as well as drive forward actions for key business stakeholders. Supports Clinical Development Expertise Areas as needed, • Support Clinical Operations budget, forecast and long term planning, decisions, and trade-offs providing expertise and oversight to ensure efficient business outcomes. Supports Clinical Development Expertise Areas as needed, • Complete all required variance analyses for projects. Identify risks in the project forecast and opportunities to improve revenue outlook. Communicate, document and manage these on an ongoing basis., • Responsible for review of transparency reporting provided by CRO to ensure alignment with operation plan for study, • Review CRO-related contract modifications and change orders in partnership with Clinical Operations, Procurement and Finance. Identify project and budget risks and opportunities to key stakeholders., • Develop and deliver training to support effective financial management processes throughout the Clinical Operations organization. Supports Clinical Development Expertise Areas as needed, • FMV-process improvement and management of the approval process within Clinical Operations, • Financial Disclosure process improvement and end of study financial recognition, • Produces resource demand forecasting for Clinical Operations; produces demand trends for ongoing studies and supports the resource planning for new studies, • Implement continuous improvement and maintain a focus on value-add services relating to resource planning and financial planning Key Skills: • Knowledge of clinical operations process, understand concept of clinical trials Phase I-III, • Strong ability to manage and motivate colleagues in a matrix organization, • Comfort around senior management; effectively represents capabilities of team, • Ability to direct others; provide coaching and guidance to staff, • Ability to understand strategy; business acumen, • Strong problem solving and analytical skills, • Sound interpersonal, verbal and written communication skills; ability to present effectively in a variety of settings, • Ability to successfully work in a ('virtual`) team environment, • Shows commitment to and performs consistently high quality work, • Ability to identify and address issues proactively in a timely manner, • Ability to take initiative and work independently Qualifications • BA/ BS in Science, Finance or Accounting required, MBA preferred, • Relevant and progressive Finance/Resourcing roles with strong analytical and partnering track record, • Strong experience in Pharma/CRO/Biotech U.S. Pay Range $136,000.00 - $184,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Description Director, Business Development The Director, Regional BD is responsible for driving sales growth across an assigned geographic territory. This role blends strategic account farming with targeted hunting activities- balancing proactive expansion of existing accounts with the pursuit of new opportunities. By developing tailored engagement plans, building trusted relationships, and orchestrating multi-functional solution development, the Director, Regional BD drives both immediate impact and develops long-term value. Leveraging data-driven insights, this leader prioritizes time and resources to maximize territory performance and elevate Syneos Health's presence within the biopharmaceutical industry. Core Responsibilities • Develops and executes a comprehensive sales strategy for a defined book of business and geographic territory, balancing new client acquisition with growth of existing accounts., • Manages an optimized territory through data-informed prioritization of time, client opportunity, and market potential., • Identifies, engages, and nurtures key client relationships with decision-makers, influencers, and stakeholders at all levels., • Leads the orchestration of tailored, multi-touchpoint sales strategies based on client needs, pipeline dynamics, and strategic goals., • Drives expansion playbooks, including therapeutically aligned strategies, renewal opportunities and next-phase conversions, to deepen account value., • Collaborates closely with cross-functional teams-including operations, therapeutic strategy, deal strategy, and delivery -to co-develop solutions that address client-specific challenges., • Acts as a client champion internally by sharing insights on client culture, preferences, and strategic priorities to enable effective team alignment and proposal development., • Educates clients on Syneos Health's differentiated value proposition, clinical and commercial capabilities, and evolving service offerings., • Conducts regular territory performance reviews, forecasts pipeline progression, and adjusts plans based on shifting client and market needs., • Maintains up-to-date records of client activity, pipeline, and sales progress within CRM platforms such as Salesforce., • Stays current on industry trends, competitor developments, and emerging client needs to continuously refine engagement strategies., • Bachelor's Degree required, advanced degree preferred, • Experience in healthcare, life sciences, or biopharma in a business development, commercial, or strategic sales role., • Proven success managing complex B2B sales cycles and navigating mid- to executive-level client relationships., • Strong consultative selling skills with a demonstrated ability to uncover client needs and co-create impactful solutions., • Excellent interpersonal, influencing, and negotiation abilities with a collaborative leadership style., • Highly organized with the ability to prioritize effectively in a fast-paced, dynamic environment., • Data-driven decision maker with strong business acumen and strategic thinking capability., • Proficient in Salesforce or similar CRM platforms; Microsoft Office Suite experience required., • Ability to travel up to 40% for client meetings, conferences, and internal events. At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements. Salary Range:121,634 - 309,733 The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role. TSP Talent Solutions and our customers are affirmative action/equal opportunity employers (Minorities/Females/Veterans/Disabled). Syneos Health Clinical BD

Job Description Who are we? A strategic and trusted insurance partner, Berkshire Hathaway Specialty Insurance (BHSI), provides a broad range of commercial property, casualty and specialty insurance coverages and outstanding service to customers and brokers around the world. Part of Berkshire Hathaway’s insurance operations, we bring our solutions to market with our stellar brand name, top-rated balance sheet, and the expertise of our global team of professionals, who exude excellent capabilities and strong character. We are a values-based organization where respect, integrity, excellence, collaboration, and passion define who we are and how we do business. We value diversity of backgrounds, experience, and perspectives and strive to foster an inclusive environment that enables all our team members to bring their best selves to work. We are one team committed to building a culture where every teammate has the opportunity to contribute and be recognized. Want to be part of the team building the finest property, casualty and specialty lines insurance company in the world? Learn more about our unique culture and history. Job Opportunity: BHSI is seeking a Finance Technology Leader to join our Enterprise Solutions team. This role is critical to driving the digital transformation of our global finance function. Reporting to the Head of Enterprise Solutions, you will partner closely with the Global Head of Finance and other key stakeholders (e.g., NICO, BHEI) to design and execute a comprehensive digital finance strategy that enhances operational efficiency, enables faster insights, and improves job satisfaction across the organization. You will lead large-scale finance technology initiatives, manage our existing suite of finance applications, and deliver scalable solutions for General Ledger & Reporting, Credit Control & Receivables, and Finance & Accounting systems. This role requires a strategic thinker with deep expertise in finance processes and technologies, strong leadership skills, and the ability to navigate the complexities of a global insurance organization. Duties and Responsibilities: • Develop and execute a digital finance transformation strategy, focusing on automation, process reengineering, and enhanced reporting capabilities., • Design and maintain a scalable, resilient finance technology ecosystem that integrates multiple financial systems and ensures accurate, efficient data flow., • Oversee the portfolio of finance-centric applications, ensuring strategic alignment, lifecycle management, and optimization to support global business needs., • Build strong business cases for finance technology initiatives and present to executive leadership for approval., • Develop and manage budgets for finance technology programs, ensuring cost efficiency and alignment with business priorities., • Lead RFP processes, vendor evaluations, and contract negotiations for finance technology solutions., • Provide regular updates to senior leadership, translating complex technical information into actionable insights., • Gain deep knowledge of BHSI’s finance technology landscape, including international requirements, multi-currency, and regulatory complexities., • Lead and motivate cross-functional, multi-disciplinary, globally distributed teams, including vendor partners, with a focus on achieving outcomes., • Drive change management and adoption strategies to ensure successful implementation of new technologies., • Collaborate with all key stakeholders to align technology initiatives with BHSI’s long-term goals, assume positive intent, and exhibit a growth mindset., • Identify and remediate technical debt and vulnerabilities to reduce risk and maintain system reliability., • Monitor and report on key performance indicators for finance technology initiatives, ensuring continuous improvement and measurable impact., • Drive application portfolio rationalization and lifecycle planning to maximize value and reduce complexity., • Maintain and optimize existing finance applications, tools, and platforms to ensure security, reliability, and availability. Qualifications, Skills, and Experience: • 15+ years of progressive experience in Information Technology, including leadership roles in finance technology, application management, program management, or enterprise transformation., • Proven track record of delivering large-scale, mission-critical finance technology initiatives from strategy through execution, ideally in global or highly regulated environments., • Deep understanding of finance processes and systems, including General Ledger, Reporting, Credit Control, Receivables, Accounting, and reconciliation workflows., • Strong data-driven mindset, leveraging analytics for decision-making, performance measurement, and continuous improvement., • Strategic thinking with the ability to construct and articulate a long-term vision for finance technology and application portfolio management., • Strong decision-making and problem-solving capability, with a focus on risk mitigation and operational excellence., • Executive presence and ability to influence at all organizational levels, including senior leadership and cross-functional teams., • High ownership mindset, demonstrating accountability, delivery focus, and a commitment to continuous improvement., • Experience collaborating with business leaders, enterprise architects, and technical teams to align technology solutions with business objectives., • Technical background or hands-on experience in enterprise applications, cloud platforms (Azure/AWS), integrations, and architecture is desirable., • Advanced analytical and portfolio management skills, with ability to evaluate application value, cost, risk, and performance to inform strategic decisions., • Experience with global finance operations, including multi-currency and regulatory compliance requirements., • Good understanding of financial reporting standards and audit processes., • Proven ability to manage vendors and contracts for finance technology solutions., • Knowledge of data governance, security, and compliance frameworks for financial systems., • Prior experience in insurance or financial services industry is a plus., • Demonstrated success in change management and stakeholder adoption for large-scale technology initiatives., • Strong technical expertise in finance technology platforms and digital finance tools., • Experience integrating multiple finance applications to create a seamless ecosystem. BHSI Offers: • A competitive package and exciting growth opportunities for career-oriented teammates., • A dynamic, action oriented, and thoughtful environment centered on always doing the right thing for our customers, teammates, and our other stakeholders., • A purposely non-bureaucratic organization that embraces simplicity over complexity and emphasizes individual excellence in a team framework., • Benefits that support your life and well-being, which include:, • Comprehensive Health, Dental and Vision benefits, • Disability Insurance (both short-term and long-term), • Life Insurance (for you and your family), • Accidental Death & Dismemberment Insurance (for you and your family), • Flexible Spending Accounts, • Health Reimbursement Account, • Employee Assistance Program, • Retirement Savings 401(k) Plan with Company Match, • Generous holiday and Paid Time Off, • Tuition Reimbursement, • Paid Parental Leave The base salary range for this position in Boston is $200,000 to $250,000, along with annual bonus eligibility. Total compensation for a candidate is determined by their relevant skills, location, and experience. We value our teammates – both their capabilities and character – as demonstrated by our amazing culture. NOTE: Compensation will be commensurate with experience. This job description is not intended to be all-inclusive. Team Member may perform other related duties as negotiated to meet the ongoing needs of the organization.

Job DescriptionAbout Eyebot Eyebot is an outcome-focused technology company on a mission to make vision care accessible to everyone, equally. Headquartered in Boston’s North End and backed by top investors and the National Science Foundation, our vision test kiosk is reshaping how vision care is delivered. If you are passionate about solving big problems and building the future of vision care, we would love to hear from you. About The Role We are looking for a Head of Quality to build and lead Eyebot’s quality and regulatory function as we scale our medical device operations across the United States and prepare for expansion into the European Union. You'll work closely with the engineering team to establish and maintain design controls, risk management, and verification and validation processes that meet FDA and international regulatory requirements. Note: This is a full-time, onsite role based in Boston’s North End. We work together five days a week to support rapid prototyping and cross-functional collaboration. What You’ll Do: * Drive regulatory strategy and submissions for U.S. and international markets, including EU MDR, UKCA, and other global certifications, while maintaining ongoing compliance and reporting. * Develop and lead Eyebot’s quality management system (QMS) to ensure compliance with FDA, ISO 13485, and international regulations. What We're Looking For:Required Qualifications: * Deep experience with medical device quality systems. * Strong understanding of FDA requirements, including 510k exempt pathways. * Knowledge of EU MDR and international regulatory frameworks. * Experience with QMS implementation and ISO 13485. * Experience with risk management, design controls, CAPA, document control. * Ability to collaborate with engineering and operations in a fast moving environment. Required Regulatory Experience: * Hands-on experience leading medical device certifications in one or more of the following regions: EU (MDR), UK (UKCA), Canada (Health Canada / MDSAP), Mexico (COFEPRIS). * Demonstrated experience working directly with Notified Bodies and regulatory authorities. * Strong working knowledge of EU MDR, including PRRC (Article 15) responsibilities. * Experience owning PMS, vigilance, and regulatory reporting processes. Preferred Qualifications: * Previous experience formally acting as a PRRC or equivalent regulatory accountability role. * Experience supporting EU MDR Class IIa medical device certifications. * Experience scaling quality and regulatory systems in a high-growth startup environment. * Experience supporting or fulfilling MDR PRRC accountability requirements, including preparation and maintenance of MDR technical documentation and hands-on support of MDR CE certification activities with Notified Bodies. Personality: * You are energized by fast-paced environments and excited to grow with a startup that is scaling quickly. * You take ownership of your work and care deeply about quality. * You hold yourself and your teammates to a high bar. * You follow through on commitments and take responsibility for outcomes. * You bring a low ego, collaborative mindset. You are easy to work with, open to feedback, and able to keep perspective even when things don't go according to plan. What We Offer: * Starting target salary in the range of 150k-220k, along with meaningful equity. * Flexible work schedule with unlimited PTO. * A culture where every idea is welcome, no matter how out there it sounds — that’s how Eyebot got started. * Full health, dental, and vision insurance. * Commuter support and wellness benefits. * A collaborative office environment in Boston’s North End, with regular team lunches and a great waterfront location. * The chance to build products that improve lives and redefine how vision care is delivered.

We Are Looking for a Builder The Rasner Group is seeking a Director of Operations to serve as the operational leader of our real estate team. This role is for someone who thrives on building systems, leading people, and scaling organizations. You will work directly with the CEO to design and implement the operational infrastructure required to support the next stage of our growth. This is not an administrative role. This is a leadership role responsible for building the operational engine of the business. About The Rasner Group The Rasner Group is a high-performing real estate team serving the Greater Boston area. Our focus is delivering exceptional client service while building a scalable and sustainable business. We are now entering the next phase of growth and are looking for a leader who can build the systems, accountability structures, and operational processes that allow our agents to perform at their highest level. Your Mission Your mission is to build and lead the operational infrastructure that supports the growth of the business. You will design systems, lead the operations team, track performance metrics, and ensure the business runs with clarity, structure, and accountability. You will function as the integrator of the organization, turning strategy into execution. What You Will Own Operations & Systems • Design and implement scalable operational systems, • Optimize workflows for listings, buyers, and transaction management, • Recruit, hire, and develop operations staff, • Lead team meetings and accountability systems, • Manage budgeting, payroll, and commission tracking, • Monitor financial performance and operational costs, • Track KPIs and team performance metrics, • Implement accountability structures, • Translate company vision into executable systems, • Support recruiting and onboarding of agents, • Help scale the organization through operational excellence Who You Are You are a systems thinker who enjoys building organizations. You thrive in fast-moving environments and take ownership of problems. You have the ability to see the big picture while also executing the details. You are comfortable making decisions, holding people accountable, and implementing systems that improve performance. What We’re Looking For • 3–7+ years of operations leadership experience, • Experience building business systems and processes, • Strong organizational and project management skills, • Financial literacy and budgeting experience, • Strong communication and leadership ability, • Experience in real estate or a similar service-based business preferred Compensation Base Salary: $80,000 – $120,000 Performance Bonus: $20,000 – $40,000 potential Profit Share Opportunity Total Target Compensation: $110,000 – $160,000+ Why This Role Is Unique This is an opportunity to help build and scale a high-performing real estate organization. The right person will have the ability to shape the future structure of the company and grow alongside the business. If you are an operator who enjoys building systems, leading people, and scaling organizations, we would love to connect.

Founded in 1882, the Harvard & MIT Cooperative Society—known as The COOP—is one of the most iconic collegiate retail institutions in the country. Today, the COOP is in the midst of an exciting transformation—reimagining its role not just as a retailer, but as a platform for connection, community, and engagement across Harvard, MIT, and the neighborhoods they call home. About the Role We are seeking a highly motivated and experienced E-Commerce Manager to lead the performance and day-to-day operations of our online business. This role is responsible for driving revenue growth, optimizing the customer experience, and ensuring seamless execution across our digital storefront. This is a critical leadership position that will own the digital P&L and play a key role in scaling our online business to the next level. Key Responsibilities Digital Store Operations & Experience • Oversee the day-to-day management of our e-commerce platform (Shopify), ensuring site functionality, uptime, and performance, • Continuously optimize the customer journey, navigation, and overall user experience, • Manage product assortment, categorization, and on-site merchandising strategy, • Oversee product launches, ensuring accurate setup, pricing, imagery, and descriptions, • Execute promotional campaigns, seasonal updates, and homepage refreshes, • Monitor and report on key performance indicators including conversion rate, average order value (AOV), traffic, and revenue, • Identify opportunities to improve conversion and drive incremental sales, • Develop forecasts and track performance against business goals, • Collaborate closely with marketing to align on campaigns, traffic-driving initiatives, and promotional calendars, • Partner with fulfillment and operations teams to ensure accurate inventory, timely shipping, and strong customer experience, • Continuously test and optimize site performance (CRO), including landing pages, product pages, and checkout flow, • Identify opportunities to expand product offerings and improve pricing strategies, • Support SEO and on-site search optimization efforts Qualifications • 4–7+ years of experience in e-commerce, digital retail, or direct-to-consumer (DTC) businesses, • Hands-on experience managing platforms such as Shopify, Klaviyo, SKUlab, • Strong understanding of digital merchandising, customer experience, and online retail operations, • Proven ability to analyze data and translate insights into actionable strategies, • Experience managing product catalogs, promotions, and site content, • Familiarity with analytics tools (Google Analytics, Shopify analytics, etc.), • Excellent organizational and project management skills, • Strong communication skills with the ability to work cross-functionally Preferred Qualifications • Background in retail merchandising or consumer products, • Experience scaling an e-commerce business in the $1M–$5M revenue range, • Familiarity with SEO, email marketing, and performance marketing concepts What We’re Looking For • A strategic thinker who can also execute at a detailed level, • A strong operator who thrives in a fast-paced, growing environment, • Someone who understands both the art and science of digital retail, • A results-driven leader focused on growth, efficiency, and customer experience Why Join Us This is an opportunity to take ownership of a growing digital business and play a key role in shaping its future. You’ll have the ability to make a meaningful impact on revenue growth, customer experience, and brand development.

Job Description We are a healthcare technology company that provides platforms and solutions to improve the management and access of cost-effective pharmacy benefits. Our technology helps enterprise and partnership clients simplify their businesses and helps consumers save on prescriptions. As a leader in SaaS technology for healthcare, we offer innovative solutions with integrated intelligence on a single enterprise platform that connects the pharmacy ecosystem. With our expertise and modern, modular platform, our partners use real-time data to transform their business performance and optimize their innovative models in the marketplace. Position Summary: The Product Manager – Clinical & Authorization Platforms owns the strategy, roadmap, and execution of RxSense's clinical rules infrastructure and prior authorization capabilities. This role is responsible for the platform functionality that enables clients to configure, operationalize, and scale their clinical policies and utilization management programs. RxSense serves enterprise PBMs and healthcare organizations that define their own clinical criteria. The Product Manager ensures those client-defined rules—such as prior authorization requirements, step therapy protocols, quantity limits, refill-too-soon controls, and specialty restrictions—are accurately translated into configurable system logic and efficient workflows within the RxSense platform. This role balances flexibility and standardization, ensuring the platform supports complex client configurations while maintaining performance, scalability, automation, and a high-quality provider and member experience. To Be Successful in This Role, the Ideal Candidate Will • Develop deep expertise in prior authorization, utilization management, and clinical edit frameworks., • Understand how PBM-defined clinical criteria must be operationalized within configurable systems., • Think holistically across adjudication engines, accumulators, benefit design, network configurations, and hierarchy-based (OCAG) inheritance models., • Translate client requirements into scalable product capabilities rather than one-off custom solutions., • Balance automation and human review workflows to optimize efficiency without compromising clinical controls., • Use performance data to continuously refine rule precision, reduce false positives, and minimize provider/member friction., • Demonstrate strong systems thinking, recognizing how clinical rules interact across the broader RxSense platform architecture. Expectations Clinical Rules Infrastructure Ownership • Own the end-to-end clinical rules framework within the platform., • Ensure accurate implementation of client-defined clinical criteria into configurable system logic., • Design scalable configuration models that support multiple enterprise clients without degrading performance., • Lead the evolution of electronic PA submission, review, approval/denial, exception, and appeals processes., • Improve authorization turnaround times and automation rates., • Maintain traceability between client requirements, system configuration, and adjudication outcomes., • Partner with internal clinical SMEs and client stakeholders to implement updates tied to drug launches, safety changes, and rule adjustments., • Own and prioritize the clinical platform backlog based on enterprise scalability, client impact, and operational value., • Develop detailed feature specifications with measurable outcomes and acceptance criteria., • Collaborate closely with engineering, architecture, clinical SMEs, operations, and commercial teams., • 4+ years of experience in a PBM, health plan, or healthcare technology environment with direct exposure to prior authorization and utilization management workflows., • 4+ years working within agile product teams, healthcare operations, or related environments., • Experience working with clinical rules engines, decision support systems, or authorization platforms., • Strong understanding of how clinical criteria are operationalized within adjudication and workflow systems., • Familiarity with ePA standards and healthcare interoperability (e.g., NCPDP SCRIPT, FHIR)., • Experience operating within agile product environments and managing roadmaps/backlogs in JIRA (or similar tools)., • Proven ability to communicate effectively across engineering, clinical, operational, and executive stakeholders. RxSense believes that a diverse workforce is a more talented and productive workforce. As such, we are an Equal Opportunity and Affirmative Action employer. Our recruitment process is free from discriminatory hiring practices and all qualified applicants are considered for employment without regard to race, color, religion, sex, gender, sexual orientation, gender identity, ancestry, age, or national origin. Neither will qualified applicants be discriminated against on the basis of disability or protected veteran status. We believe in the strength of the collaboration, creativity and sense of community a diverse workforce brings.

Position Summary: Our client, a global, multi-site retail and consumer services organization, is seeking a Benefits Director to lead the day-to-day operations of their employee benefits function. This role reports directly to the VP of Total Rewards and is based on-site at the company’s office in the greater Boston area. This is a high-impact leadership role focused on overseeing the administration, compliance, and continuous improvement of benefits programs across a large, multi-state workforce, supporting both retail and corporate populations. Absolute Minimum Must-Have’s / Experience / Requirements: • Bachelor’s degree required (HR, Business, or related field), • 5–7+ years of progressive experience in benefits administration or total rewards, • Strong knowledge of benefits regulations including ERISA, HIPAA, ACA, and COBRA, • Comprehensive experience with health & welfare and retirement plan administration, • Experience with leave of absence programs, • Experience managing a team and direct reports, • Vendor management experience (brokers, TPAs, and related partners), • Advanced Excel skills (pivot tables, lookups, data analysis), • Experience administering benefits across a multi-state workforce, • Experience managing open enrollment for a large, distributed employee population, • Strong analytical and problem-solving capabilities with ability to diagnose issues and implement solutions, • Ability to translate complex benefits data into actionable insights and recommendations, • Strong understanding of internal controls, risk management, and benefits governance, • Demonstrated ability to manage multiple priorities in a fast-paced, high-volume environment, • High level of discretion, confidentiality, and sound judgment, • Strong program and process management skills Key Responsibilities: What You’ll Do • Oversee administration of all health, welfare, and retirement benefit programs, ensuring accuracy, efficiency, and strong internal controls, • Partner with HRIS, Payroll, and Finance to ensure seamless benefits operations including enrollment, billing, and data integrity, • Lead end-to-end open enrollment strategy and execution, including communications and employee education across corporate and field populations, • Manage vendor relationships including brokers, third-party administrators, and other partners, ensuring accountability and service delivery, • Ensure full compliance with all federal, state, and local regulations and maintain all required plan documentation and communications, • Analyze benefits utilization, market trends, and cost data to support plan renewals and program effectiveness, • Support ongoing efforts to enhance the competitiveness and cost-effectiveness of benefit offerings, • Serve as escalation point for complex benefits issues, ensuring a strong employee experience, • Lead, develop, and coach the benefits team, fostering a high-performing and service-oriented culture, • Partner cross-functionally to improve data quality, reporting, and system capabilities Key Desired Business Outcomes What Success Looks Like First 6 Months: • Build strong relationships with Total Rewards, HR, Finance, Payroll, and key vendor partners, • Assess current benefits programs, processes, and systems to identify gaps and improvement opportunities, • Gain full understanding of existing plans, costs, and employee utilization, • Identify and address any immediate compliance or operational risks, • Establish clear priorities, workflows, and expectations for the benefits team, • Successfully execute a full open enrollment cycle across a large, distributed workforce, • Support improvements to benefits programs to enhance competitiveness and cost efficiency, • Establish reliable benefits data, reporting, and operational processes, • Ensure full compliance with all regulatory requirements, • Build a high-performing, process-driven benefits team with strong vendor management, • Be recognized as a trusted resource for benefits across the organization

Position Summary: Our client, a global, multi-site retail and consumer services organization, is seeking a Director of Training to lead and modernize their enterprise learning function. This role reports to the VP of Talent Management and is based on-site at the company’s office in the greater Boston area. This is a high-impact leadership role focused on building and scaling training programs across a large, multi-state retail footprint, supporting both field operations and corporate populations. Absolute Minimum Must-Have’s / Experience / Requirements: • Bachelor’s degree required; advanced degree in L&D, Organizational Development, I/O Psychology, HR, or related field preferred, • 10+ years of experience in learning & development, with at least 5+ years in leadership roles, • Deep experience supporting retail or high-volume frontline workforce training environments, • Strong expertise in adult learning principles, instructional design, and diverse learning methodologies, • Proven track record of modernizing learning programs through technology and innovative delivery methods, • Experience with LMS/LXP platforms and learning technologies, • Demonstrated ability to scale training programs across large, distributed organizations, • Strategic mindset with the ability to translate business priorities into scalable training initiatives, • Strong analytical and problem-solving capabilities with experience measuring training effectiveness, • Knowledge of performance management, talent development, and organizational dynamics, • Experience leading through change and operating in complex, fast-paced environments, • Strong program and project management skills with the ability to manage multiple initiatives, • Ability to build structure and processes in ambiguous or evolving environments Key Responsibilities: What You’ll Do • Serve as the subject matter expert for training and development across retail field operations and corporate functions, • Develop and execute a comprehensive training strategy aligned with operational priorities and business goals, • Oversee training programs for frontline associates and field leadership, including onboarding, compliance, and leadership development, • Partner closely with Operations leadership to identify performance gaps and translate them into effective training solutions, • Drive consistency across a large, multi-site footprint through standardized, scalable learning programs, • Design and implement leadership development programs to build a strong internal talent pipeline, • Modernize the training function by transitioning to more engaging, technology-enabled learning experiences, • Lead the evaluation, selection, and implementation of learning platforms and tools, • Ensure training supports key operational initiatives and evolving business needs, • Enhance leadership capability in areas such as performance management, coaching, and employee engagement, • Support corporate training initiatives, including onboarding and professional development programs, • Partner with HR and business leaders to address capability gaps and support organizational effectiveness, • Foster a culture of continuous learning across both field and corporate populations Key Desired Business Outcomes What Success Looks Like First 6 Months: • Build strong relationships with training team, Operations leadership, and key stakeholders, • Assess current training programs, content, and systems to identify gaps and opportunities, • Gain a clear understanding of ongoing initiatives and immediate priorities, • Identify quick wins to improve consistency and effectiveness across the field, • Begin developing a modernized training roadmap aligned with business goals First 12 Months: • Successfully modernize core training programs to more scalable, technology-enabled formats, • Establish structured leadership development programs to support internal talent pipelines, • Implement or significantly enhance learning systems and platforms, • Develop clear training metrics and demonstrate impact on business performance, • Build a high-performing, structured training team with clear priorities and expectations, • Be recognized as a trusted partner in driving performance through training and development

Job Description Who are we? A strategic and trusted insurance partner, Berkshire Hathaway Specialty Insurance (BHSI), provides a broad range of commercial property, casualty and specialty insurance coverages and outstanding service to customers and brokers around the world. Part of Berkshire Hathaway’s insurance operations, we bring our solutions to market with our stellar brand name, top-rated balance sheet, and the expertise of our global team of professionals, who exude excellent capabilities and strong character. We are a values-based organization where respect, integrity, excellence, collaboration, and passion define who we are and how we do business. We value diversity of backgrounds, experience, and perspectives and strive to foster an inclusive environment that enables all our team members to bring their best selves to work. We are one team committed to building a culture where every teammate has the opportunity to contribute and be recognized. Want to be part of the team building the finest property, casualty, and specialty lines insurance company in the world? Learn more about our unique culture and history. Job Opportunity: Berkshire Hathaway Specialty Insurance (BHSI) has an exciting opportunity for an experienced technology portfolio leader to join our Boston-based Technology team as AVP, Portfolio Management (EPMO). This is a unique opportunity to join a global organization and drive meaningful change in how we work. This critical role sits within our Technology Strategy & Planning team and will bring transparency and discipline into how initiatives are received, evaluated, prioritized, tracked, and measured for our global technology portfolio. This role will partner closely with executive and senior leaders (technology and business) across regions (North America, Europe, Asia Middle East, and Australasia) and global functions to ensure strategic priorities translate into executable plans and measurable outcomes. A key focus of this role is building the foundational capabilities to enable enterprise portfolio excellence in both process and tooling. You will facilitate governance forums, define ownership and decision rights, establish clear prioritization criteria, and introduce consistent success metrics. You will facilitate planning for the annual budget cycle. You will collaborate closely with agile delivery leaders and other departments to select and implement a portfolio management tool and governance process that integrates with existing systems and processes, reducing manual status reporting for key initiatives. The ideal candidate is passionate about evolving portfolio and delivery practices, strengthening cross-functional partnerships, and maintaining a strong focus on business outcomes. Success in this role requires executive-level communication and facilitation skills, a data-driven mindset, strong change leadership aptitude, and a high degree of self-awareness and emotional intelligence. If you are looking for a career defining leadership opportunity that can transform how we work, this is the job for you. Duties & Responsibilities: • Lean Portfolio Management (LPM): Establish and operationalize Lean Portfolio Management practices, driving better organization and governance around how we gather, prioritize, deliver, and measure initiatives globally, • Portfolio Governance: Establish and facilitate enterprise portfolio governance forums to review demand, sequence work, manage in‑flight reprioritization, and resolve cross‑portfolio dependencies and conflicts; Define roles, responsibilities, and decision rights to ensure clear ownership, accountability, and timely escalation, • Intake and Prioritization Process: Implement a standardized intake process and clear prioritization criteria to enable transparent trade-off discussions and improve funding decisions, • Portfolio Strategy and Alignment: Oversee all aspects of the technology portfolio to ensure alignment with corporate strategy, business priorities, technical roadmaps, and financial objectives while balancing innovation, operational stability, and risk, • Benefits Realization and ROI Analysis: Establish best practices and consistency around delivery metrics (predictability, quality, and business value delivery) and partner with key stakeholders (such as the CFO and global business leaders) to measure ROI and report on benefits realization, • Business Process Mapping: Lead the effort to document and analyze business and technical processes to identify opportunities to simplify, reduce handoffs, and ultimately improve efficiency., • Tooling and Integration: Lead the evaluation, selection, and implementation of a technology portfolio management tool, ensuring seamless integration with Agile backlog management tools and collaborating with other departments to align on a shared enterprise platform, • Stakeholder engagement: Partner with executive and senior leaders across business and technology gather input, communicate status and risks, and drive alignment cross-functionally, • Change Management and Adoption: Drive change management to embed a Lean/Agile mindset and drive adoption of new ways of working across the organization, • 15+ years of progressive leadership experience in technology portfolio management, strategy, planning, or operations, • Proven experience establishing and maturing enterprise portfolio management practices (e.g., intake, prioritization, governance, and transparency) and driving adoption across global stakeholders, • Deep understanding of Lean Portfolio Management and portfolio governance, including capacity-based prioritization and sequencing of work, • Demonstrated success designing and implementing standardized intake, prioritization, and evaluation processes, • Strong analytical skills and ability to deliver executive-level dashboards/insights on portfolio health, performance, and risk to inform decisions, • Excellent communication and stakeholder management skills, with the ability to influence and align senior leaders across business, technology and finance, • Experience with Enterprise Portfolio Management (EPM/PPM) platforms (such as Jira Align, Planview, Planisware) to support portfolio planning, prioritization, financial transparency, and executive decision making., • Experience integrating EPM/PPM tools with agile backlog management tools for automated status tracking and timeline projections, • Experience with business process mapping (documenting and analyzing) to optimize processes, • Demonstrated success leading organizational change and modernizing portfolio and delivery practices to improve transparency and outcomes, • Proven ability to lead with self-awareness and emotional intelligence, adapting style based on context and feedback while maintaining accountability, • Experience in insurance, financial services, or a similarly complex, regulated industry, • Program Management Certification such as PMP, PMI-ACP, CAPM, PgMP, PRINCE2 or similar, • A competitive package and exciting growth opportunities for career-oriented teammates., • A dynamic, action oriented, and thoughtful environment centered on always doing the right thing for our customers, teammates, and our other stakeholders., • A purposely non-bureaucratic organization that embraces simplicity over complexity and emphasizes individual excellence in a team framework., • Benefits that support your life and well-being, which include:, • Comprehensive Health, Dental and Vision benefits, • Disability Insurance (both short-term and long-term), • Life Insurance (for you and your family), • Accidental Death & Dismemberment Insurance (for you and your family), • Flexible Spending Accounts, • Health Reimbursement Account, • Employee Assistance Program, • Retirement Savings 401(k) Plan with Company Match, • Generous holiday and Paid Time Off, • Tuition Reimbursement NOTE: Compensation will be commensurate with experience. This job description is not intended to be all-inclusive. Team Member may perform other related duties as negotiated to meet the ongoing needs of the organization.

Discover What's Possible at BetMGM Ready to make your career legendary? Join us as we bring the magic of Vegas to our players. The BetMGM team has over 1,400 talented members, revolutionizing sports betting and online gaming in the United States and Canada. We're a brand with technology at our hearts and the most driven and focused talent in the business. As a valued team member, we're committed to giving you the resources and support you need to thrive. Our benefits and perks include: * Medical, Dental, Vision, Life, and Disability Insurance * 401(k) with company match * Pre-tax spending accounts including health care FSA and commuter savings * Flexible paid time off * Professional development reimbursement and ongoing skills training opportunities * Employee resource groups * Swag, ticket giveaways, and more! At BetMGM, we recognize that every individual plays a meaningful role in our success. That's why we're committed to building a respectful, inclusive workplace. It's the strategy behind every win. By meeting people where they are, we create a culture of belonging where everyone can thrive and a workplace that reflects our values, our people, and our drive to win. About the Role Legal Counsel will advise the business on legal and commercial matters relating to new and existing partnerships and agreements. The position is responsible for negotiating, drafting, and reviewing new and existing commercial agreements and assisting in advancing the Company's commercial initiatives in compliance with all laws and regulations. Legal Counsel, working under the direction and supervision of Associate General Counsel, will have specific responsibilities in the areas of commercial contracts and legal operations; however, this individual will be expected to operate independently and maintain accountability over the individual's area of responsibility. This individual will be responsible for actively managing relationships with both internal and external stakeholders, while serving as a reliable and knowledgeable liaison between the business and Legal department. This role may be based in Jersey City, New Jersey, or can be done remotely. Responsibilities * Review, draft and negotiate commercial contracts (examples below) and provide strategic and proactive legal advice to business clients. * Examples of agreement types: Payment processing agreements, vendor agreements (MSAs/SOWs for marketing, technology, data, and intellectual property contracts), use license agreements, market access agreements, partnership agreements, sponsorship agreements, affiliate agreements, and promotions (sweepstakes, contests). * Ability to draft and synthesize key clauses and create bespoke agreements in connection with unique business transactions. * Leverage AI enabled tools to efficiently review and draft commercial agreements and support timely, data informed legal guidance to business partners. * Adopt a collaborative approach with business partners to lead negotiations with partners, suppliers, and affiliates across different business functions. * Manage multiple assignments simultaneously and possess the ability to correctly prioritize and triage the same. * Maintain an effective and organized executed contract repository utilizing the company's contract management system. * Assess risks and use sound business and legal judgment to respond to questions, make decisions, and negotiate deals to meet deadlines in a fast-paced environment. * Inspire confidence in business partners by consistently providing well-reasoned legal advice and practical and creative solutions to complex issues. * Demonstrate confidence in risk-managed decision making and judgment. * Proactively identify and advise on legal issues arising from potential and existing commercial relationships. * Collaborate with, support, and advise business partners on a wide array of contractual and commercial matters requiring legal advice (examples include product, technology, sports betting and gaming operations, marketing, finance, and human resources. * Assist in various team projects and initiatives, including making continuous improvements to commercial legal processes, liaising with business partners to assist in creating or improving relevant policies, revising and updating contract templates, driving adoption of company's contract management tool. * Exhibit a strong work ethic and take ownership of complex projects and contract reviews with minimal supervision while demonstrating sound judgment and superior decision-making, multi-tasking, and problem-solving skills. * Demonstrate leadership and teamworking skills in support of a collaborative environment. * Exhibit utmost professionalism in all settings; be capable of deploying strong advocacy skills in a tactful and effective manner while maintaining complete credibility with all stakeholders. * Consistently produce excellent work product. * Establish and maintain positive and effective working relationships with co-workers, internal clients, and external business partners. * Maintain confidentiality of sensitive information and demonstrates the highest integrity in all settings. * Coordinate cross-functional legal input by working closely with other attorneys in the legal department. * Perform other job-related duties as assigned by Associate General Counsel. Qualifications * Juris Doctor Degree required. * Minimum of three years of being a licensed attorney with progressive responsibility in reviewing and negotiating contracts. * Experience practicing law in a top-tier law firm and/or equivalent in-house experience. * Experience working in an in-house legal department, regulated industry, and/or negotiating technology services, software, SaaS transactions preferred. * Gaming license registration as required by applicable jurisdictions. * Substantive knowledge and understanding of legal strategies and principles related to contract drafting and negotiating; ability to analyze and apply legal principles and precedents to legal issues; ability to perform legal research, evaluate alternatives and make sound recommendations. * Basic proficiency in MS Word, Excel, PowerPoint and MS Outlook. * Experience working with a contract management tool preferred. Applicants must possess legal authorization to work for our company in the U.S. without the need for immigration sponsorship. At this time, this role is not eligible for immigration-related employment authorization sponsorship including H-1B, O-1, E-3, TN, OPT, etc. Gaming Compliance & Licensing Requirements As an online gaming company, BetMGM is required to comply with state gaming regulations which includes licensing obligations. Applicable employees must be licensed by at least one jurisdictional agency, although certain positions require licensing by multiple agencies. Failure to become licensed or maintain licensure with each agency as required for the role may result in termination of employment. Please note that the licensing process includes comprehensive background checks which may include a review of criminal records, financial history, and personal background verification. In addition, candidates must comply with and support BetMGM's responsible gambling policies, procedures, and initiatives. About BetMGM BetMGM is revolutionizing sports betting and online gaming in the United States and Canada. We are a partnership between two powerhouse organizations-MGM Resorts International and Entain Group. You know our name through our exciting portfolio of brands including BetMGM Casino, BetMGM Sportsbook, Borgata Online, Party Casino and Party Poker. We aim to bring our ideas into action and find ways to deliver the best quality in gaming platforms. BetMGM LLC is an Equal Opportunity Employer. We provide equal employment opportunities to all qualified individuals, regardless of race, religion, gender, gender identity, age, marital status, national origin, sexual orientation, citizenship status, veteran status, disability, or any other legally protected status. As an organization, we are unwavering in our commitment to maintaining a discrimination-free work environment, and fostering a culture of inclusivity, belonging and equal opportunity for all employees and applicants. If you need assistance or accommodation with your application due to a disability, you may contact us at . This job description is not an exclusive or exhaustive list of duties a person in this position may be asked to perform from time to time. #LI-REMOTE #LI-IK1

About Us Based in Parma, Italy, Chiesi is an international research-focused biopharmaceutical group with 90 years' experience, operating in 31 countries. More than 8,000 employees across the group are united by a singular purpose: promoting a healthier world for our people, patients, and the planet. This is what drives us as we research, develop, and market innovative drugs across our main therapeutic areas. ___ At Chiesi we are thinking generations ahead, driving sustainable innovation with purpose. This fosters a culture of reliability, transparency, and ethical behaviour at every level. As a Benefit Corporation and a certified B Corp, we have embedded sustainability in our bylaws and continuously measure our impact. Diversity, inclusion, and equal opportunity are at the heart of who we are. We believe our differences make us stronger. We are a vibrant ecosystem of passionate, talented individuals united by strong values, each bringing unique perspectives that help us to continuously challenge the status quo for the better. Chiesi Global Rare Diseases Chiesi Global Rare Diseases is a Chiesi Group's business unit established in February 2020 and focused on research, development and commercialization of treatments and patient support services for rare and ultra-rare disorders, many of whom have limited or no treatments available. This unit is based in Boston, Massachusetts, with a strong synergy with the headquarters in Parma. Rare unit has a focus on research and product development for lysosomal storage diseases, rare hematology, ophthalmology disorders and rare immunodeficiencies. The unit is also a dedicated partner with global leaders in scientific research, patient advocacy and care. ___. Who we are looking for About this position: The position of Medical Affairs Manager reports to the Associate Director, Medical Strategy - Cardio-Metabolic, North America. This position is a member of the Global Medical Affairs team supporting the development and implementation of the products' Global Medical strategy and acting as an internal subject matter expert within the therapeutic area. • Demonstrate scientific and business expertise, including products, disease state and management, emerging therapies, and the competitive landscape, • Contribute to medical affairs strategy development and execute short to medium-term medical projects and initiatives under the leadership of the Associate Director, Medical Strategy- Cardio-Metabolic, • Execute specific medical affairs activities within the cardio-metabolic portfolio in US and Canada, including support to data generation, conference planning and medical education events, • Help plan and conduct advisory boards and round table meetings, • Provide input and support to publication planning to ensure that data generated by company or (investigator) sponsored trials is publicly presented in an appropriate and timely fashion and in a fair and balanced manner, • Coordinate scientific review and approval of medical materials in compliance with corporate standards and government/industry regulations, • Manage medical materials preparation and review, facilitate meetings, gather and address comments from Medical Review Board members, • Perform medical review on promotional materials, • Support meetings with external key opinion leaders to obtain insights and guidance on clearly defined scientific/medical activities or plans, • Represent Chiesi at meetings and conferences, and in other interactions with key opinion leaders in collaboration with other functions, • Liaise with field medical team on key external relationships for ongoing project and engagement between the KOLs and medical affairs, • Manage project plans, assess resource needs and assist in other medical affairs responsibilities as needed, • Scientific degree: MSc in life sciences, MD, PhD, PharmD or a nursing degree with relevant experience, • Able to work and align with multiple Chiesi-internal and external stakeholders and build and navigate within cross-functional Chiesi teams, • Transfer and articulate scientific and clinical data into clear conceptual frameworks, disease management approaches and a pathway to continuously strengthen this concept by new medical evidence, • Effective at giving presentations to internal and external audiences on the medical and clinical aspects of a given disease, product, or program, • Ability to thrive in a dynamic and fast-paced team environment, • Well-organized, operationally effective, and able to both develop project strategies and ensure reliable implementation of projects with a flexible and solution-focused mindset, • Proven planning and organizational skills with experience managing multiple priorities in combination with attention to detail and the ability to prioritize in a changing environment with a sense of urgency, • Strong interpersonal skills in developing and maintaining successful stakeholder relationships (internal and external), • Proven ability to collaborate across organizational boundaries, • Entrepreneurial mindset and problem solving skills, • This position may be filled as a Scientist or a Senior Scientist, depending on skills, education and experience, • Experience in endocrinology, lipidology, cardiology, and/or rare disease The annual base pay for this position ranges from $142,110 to $173,690. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. If hired, the employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. What we offer No matter where your path starts at Chiesi, it leads to inspiring possibilities. Your future is our focus, and we are committed to nurturing your development in our dynamic, friendly environment with access to resources and training every step of the way. We provide top-class benefits, including comprehensive healthcare programs, work-life balance initiatives, and robust relocation support. Our salary package is competitive, comprising a basic salary, performance bonuses, and benefits benchmarked against the external market. Additionally, we offer flexible working arrangements, remote work options, and tax assistance services for foreign colleagues, all designed to help you thrive. Chiesi USA is an equal opportunity employer committed to hiring a diverse work force at all levels of our business. All qualified applicants receive consideration for employment without regard to race, national origin, age, sex, religion, disability, marital status, veteran status, or any other basis protected by local, state or federal law. This policy applies with regard to all aspects of one's employment, including hiring, transfer, promotion, compensation, eligibility for benefits and termination.

Job Title: Clinical Oncology Specialist Location: Boston, MA We are seeking a mission-driven field professional to spearhead strategic growth for a specialized diagnostic solution across key markets. This role focuses on building strong provider partnerships, driving the adoption of evidence-based tools, and integrating services into multidisciplinary care pathways to maximize clinical impact. Key Responsibilities: • Build and manage a healthy pipeline of healthcare clients across the assigned territory, • Drive service utilization by securing new accounts and expanding within existing high-value groups, • Facilitate integration of service offerings into clinical decision-making and digital systems, • Partner with multidisciplinary care teams to align complex services with evidence-based protocols, • Collaborate with internal teams (medical, technical, client support, and operations) to ensure a seamless experience for providers, • Serve as a subject matter resource for clients, delivering presentations, training, and in-services as needed, • Attend key regional and national industry events to engage stakeholders and stay current on market dynamics, • Own account strategy and depth across a mix of institutional and group-based practices, • Deliver on key performance metrics, proposals, and territory growth targets, • 5+ years of experience in strategic account development within health systems or multi-specialty medical groups, • 3+ years in consultative sales, clinical diagnostics, or medical technology solutions, • Proven track record of launching and scaling new offerings in regulated, clinical settings, • Experience with provider adoption processes, including committee approvals or formulary review, • Highly adept at navigating complex decision-making environments involving clinicians, administrators, and health system stakeholders, • Strong presentation, communication, and consultative selling skills, • Hunter mindset with the ability to work independently in a fast-paced, field-based environment, • Bachelor’s degree required; background in healthcare, life sciences, or related field preferred This role provides a unique opportunity to make a meaningful impact in oncology, delivering clarity and hope to patients and healthcare providers through innovative precision oncology solutions.

Torticity builds technology that powers complex, operations-heavy workflows connecting internal teams, partner law firms, and claimants. We operate at the intersection of legal, operations, and technology—designing systems that increase efficiency, accuracy, and scale. We’re in a 0→1 phase across multiple products, with a strong focus on AI-driven workflows and automation to transform how work gets done. We’re looking for a Senior Product Manager to own a high-impact product area end-to-end. This is a builder role—ideal for someone who thrives in ambiguity, moves quickly, and is excited to shape products from the ground up. You will define strategy, prioritize across competing inputs, and partner closely with Engineering and Design in a triad model to ship meaningful outcomes. You’ll also work cross-functionally with Operations and senior leadership to ensure alignment and execution. * Define the vision, strategy, and roadmap for your product area * Establish clear success metrics and track performance over time * Make high-quality prioritization decisions across multiple stakeholders * Synthesize insights from internal teams, law firms, and end users (claimants) * Identify high-impact problems and validate opportunities * Frame hypotheses, define KPIs, and run experiments to de-risk ideas * Partner with Engineering and Design to scope, build, and ship products quickly * Write clear product requirements (PRDs) and iterate based on feedback * Balance speed and quality in a fast-moving environment * Leverage AI tools to accelerate your workflow and improve product experiences * Rapidly prototype solutions to test ideas before full investment * Identify opportunities to embed AI into core product functionality * Analyze product performance and user behavior * Report on outcomes and continuously refine based on data and feedback * Contribute to product culture, processes, and scaling best practices * Help establish frameworks for decision-making and execution as the company grows * 5+ years of product management experience, with ownership of end-to-end product areas * Experience in 0→1 environments or complex operational domains (e.g., fintech, insurtech, marketplaces) * Proven ability to prioritize effectively in ambiguous, multi-stakeholder environments * Strong analytical skills with experience defining and tracking metrics/KPIs * Excellent communication and stakeholder management skills, including working with senior leadership * Hands-on experience with AI tools—either shipping AI-enabled products or deeply integrating AI into your workflow * Comfort with technical concepts such as APIs, system integrations, and data flows * Experience in B2B2C platforms or multi-sided marketplaces * Background working closely with operations-heavy workflows * Experience building or scaling AI-powered features or automation systems

Company Overview Flosum is a Salesforce-native DevOps and data protection platform trusted by enterprises across technology, financial services, healthcare, energy, and the federal government. We operate with a lean, high-performance culture where every team member has outsized impact. We are financially sustainable, AI-forward, and growing — and we need someone exceptional to help our CEO operate at peak effectiveness across both the business and his personal office. The Role The ideal candidate will reside in San Ramon California, or in the Bay Area. This is not a typical executive assistant position. You will serve as the operational right hand to Flosum's CEO, managing a blend of professional and personal operations that require intelligence, discretion, financial literacy, and legal awareness. Think of yourself as a one-person chief of staff for the CEO's entire life — investments, legal coordination, family logistics, office administration, and everything in between. You will be the single point of accountability for ensuring that nothing falls through the cracks across a complex, fast-moving set of responsibilities. If you thrive on variety, can context-switch between a tax filing and a college application in the same hour, and want a role where you learn how a CEO actually operates day to day — this is it. Who You Are • You are sharp, driven, and high-energy with an insatiable appetite for learning and getting things done, • You have a baseline understanding of personal finance, investments, and tax processes — enough to be dangerous and ask the right questions, • You have exposure to or genuine interest in legal processes — you do not need to be a lawyer, but you should be comfortable reading a contract, understanding a filing deadline, and coordinating with attorneys without hand-holding, • You are an exceptional organizer who builds systems, not just to-do lists, • You exercise impeccable judgment and discretion — you will have access to sensitive personal and financial information, • You communicate clearly, directly, and proactively — you do not wait to be asked, • You are comfortable operating independently with minimal supervision and can manage up effectively, • You are tech-savvy and embrace AI tools to maximize your productivity What You Will Own Investment & Financial Operations • Coordinate with financial advisors, accountants, and investment managers on behalf of the CEO, • Track and organize personal investment portfolios, statements, and financial correspondence, • Manage tax preparation workflows — gather documents, coordinate with CPAs, track deadlines, and ensure timely filings for both personal and business-related obligations, • Process, organize, and resolve incoming financial paperwork, invoices, and office mail efficiently, • Serve as the primary liaison with attorneys, legal agencies, and regulatory bodies for personal and light business legal matters, • Review, organize, and track contracts, agreements, and legal correspondence, • Manage timelines for legal filings, renewals, and compliance deadlines, • Conduct basic legal research and prepare summaries to support decision-making, • Manage logistics for family-related matters including college applications, enrollment, academic deadlines, and school communications, • Coordinate medical appointments, insurance paperwork, and health-related administration for the CEO's family, • Handle personal scheduling, travel, and logistics that intersect with professional commitments, • Own the CEO's incoming mail — physical and digital — with a system for triage, action, and follow-up, • Maintain organized records and filing systems across financial, legal, and personal domains, • Identify and implement tools and processes that increase efficiency across all areas of responsibility Bachelor's degree required; coursework or certification in business, finance, pre-law, paralegal studies, or a related field is a strong plus Demonstrated ability to manage complex, multi-track workstreams with competing deadlines Experience coordinating with external professionals (attorneys, accountants, financial advisors) Familiarity with personal tax filings, investment documentation, and basic legal agreements Proficiency with productivity and AI tools — Google Workspace, Microsoft Office, and a willingness to adopt new technology aggressively Must be trustworthy, discreet, and comfortable handling confidential information What Makes This Role Special This is a rare opportunity to work directly alongside a CEO and learn how decisions get made at the intersection of business, finance, and personal life. You will not be siloed. You will not be bored. You will build skills across legal, financial, and operational domains that most people do not get exposure to until much later in their careers. If you are ambitious and want a role with real responsibility from day one, we want to hear from you. • Opportunity to shape the digital strategy at a high-growth Salesforce ISV., • Collaborative, innovative, and mission-driven culture., • Competitive compensation and benefits., • Career growth in a fast-scaling company serving global enterprises., • Be part of a global, mission-driven team, • Learn from top leaders in Salesforce DevOps and SaaS sales, • Work on exciting challenges in a rapidly growing industry

TrueCar is a leading automotive digital marketplace, and we are on a mission to make car buying and selling easy, transparent, and efficient. We work to empower consumers with data and foster connections with our network of Certified Dealers who share our belief that truth, transparency, and fairness are the foundation of a great experience. We forge partnerships to power car-buying programs for some of America’s most trusted brands. And we continually innovate to provide useful tools, research, market context, and pricing transparency to help consumers feel empowered and confident throughout their journey. As consumers’ priorities and shopping habits shifted, so did we. We are building a modern-day marketplace and invite you to join the TrueCar Crew. You can have a real and direct impact on our journey as we continue to evolve and revolutionize the car-buying and selling experience. The Opportunity: TrueCar is seeking an ambitious sales professional with a passion for helping automotive dealers grow their business. The Business Development Manager is responsible for closing accounts for their assigned book of business to achieve revenue and profitability growth aligned with strategic goals. Reporting to the Director, Dealer Services, the Business Development Manager is responsible for identifying, developing, and managing relationships at all levels within assigned and new accounts, acting as a liaison between the dealer and TrueCar, understanding the needs of the dealer, and educating dealers on TrueCar products as solutions to their dealership needs. This position requires strong coordination with cross-functional teams, including dealer performance, dealer operations, and dealer training teams. The ideal candidate for this role will reside in the greater Boston, MA area. How you will contribute to TrueCar’s success: • Identify, develop, manage, and close new business opportunities at assigned and new accounts, ensuring cross-functional and organizational alignment., • Build a strong 90-day sales pipeline to ensure a long-term and sustainable sales roadmap within your book of business., • Establish and maintain strong relationships with senior leaders and key decision-makers at dealerships., • Meet or exceed sales goals within an assigned book of business. Independently grow an assigned book of business and actively collaborate with the Account Managers group to retain accounts., • Prepare and present proposals and negotiate terms and conditions with dealers., • Support in dealer escalations with all involved functional areas, including dealer performance and sales operations teams, to assure approval and success. Support resolution of challenges where required., • Serve as liaison between the dealer, dealer performance manager, and dealer implementation team with respect to product implementation and continuous product management., • In partnership with the dealer training team, learn about new or upcoming products and features, ensuring a high level of personal proficiency in knowledge and functionality of products. Serve as subject matter expert in TC products., • Support a team environment with strong morale and positive energy anchored on sales goals., • Report and record all sales activity notes within Salesforce and communicate properly with applicable team members., • Serve as a change agent, leading change and acting as a catalyst for continuous improvement., • Support in the management of accounts receivable for assigned accounts., • Demonstrate a high level of attentiveness toward customers and actively contribute to a culture that encourages high-quality service with a sense of urgency., • Develop trusting relationships and open communication, accepting feedback (up and down)., • Additional ad hoc responsibilities as determined by the needs of the business. Your Expertise: • Proven success in retail sales in an automotive dealership environment., • Experience in digital media advertising., • Excellent communication and presentation skills, with the ability to listen for understanding, influence outcomes, and negotiate with clients., • Proven ability to identify, initiate, negotiate, and close deals., • Proven track record of consistently meeting and/or exceeding sales goals., • Ability to formulate, implement, and execute sales strategy, plans, and tactics in a competitive environment., • Experience with Salesforce or other Customer Relationship Management tool utilization., • Experience interfacing with client contacts at various levels and demonstrated ability to effectively present information, including complex technical content, and respond to dealer requirements/requests., • Demonstrated understanding of client standards and requirements as they pertain to offered products, features, and capabilities., • Strong sales skills with the ability to create tangible interest for new ideas and product opportunities with clients., • Ability to communicate client requirements and methodologies to the internal organization to ensure alignment., • High integrity, self-starter, strong work ethic, with a high level of energy., • Tech-savvy with the ability to understand, interpret, and present data using a consultative approach., • Ability to grasp new concepts quickly with an open mind for change and a willingness to solve problems., • Strong understanding of auto dealerships, both larger dealer groups and family-owned., • Ability to travel domestically by airplane or car, including overnight trips up to 75% of the time Please note that final interviews may be conducted in-person at the Company's sole discretion. Base salary + target incentive: $155,000 - $165,000 Your TrueCar Experience At TrueCar, we champion remote work because we know great work can happen anywhere. This flexibility allows our TrueCar Crew to live and work from anywhere in the U.S. (with some role-based exceptions). To support our remote team, we provide a home office setup that suits their needs and offer monthly reimbursements for phone and internet connectivity. You will receive excellent benefits that include, but are not limited to, 100% employer-paid health, vision, and dental premiums; a 401(k) plan with company contributions; a wellness reimbursement account; and learning & development reimbursement opportunities. We also understand the importance of recharging, so we offer flexible PTO for exempt TrueCar Crew Members and a generous PTO accrual policy for non-exempt TrueCar Crew Members, in addition to 14 company-paid holidays and 2 floating holidays. In short, we care deeply about our Crew Members and have designed employee-centric programs that reflect this. At TrueCar, we believe in the power of diversity to create a deeper understanding of our consumers and partners, driving innovation in our products. We welcome a workforce that reflects the diversity of car-buying consumers and encourage everyone interested in our mission to apply. We do not discriminate on the basis of race, gender, religion, sexual orientation, age, or any other characteristic protected by applicable law. We will consider qualified applicants with arrest and conviction records in accordance with applicable law. Additionally, TrueCar will provide reasonable accommodations for qualified individuals with disabilities. TrueCar does not accept unsolicited agency submissions. If you are based in California, we encourage you to read this important information for California residents linked ___. #LI-Remote

Product Manager (Automotive Fluids/Chemicals; Business dev exp req) Location: Cicero, IL (Hybrid/Remote Flex Eligible) Salary: $125,000 - $150,000 + 10%-15% Bonus Benefits: Health, Dental, Life and AD&D, 401k w/ match, PTO, Mileage Allowance, Job Type: Full-Time Typical Hours: Monday – Friday Travel: Up to 60% including national travel for tradeshows and account meetings Start Date: ASAP Sponsorship is not available Relocation assistance is negotiable Product Manager (Automotive Fluids/Chemicals; Business dev exp req) Description Our client in the petroleum distribution sector is seeking a Hybrid Product Manager to lead the launch of a new line of lubricants and functional fluids products. Based in Cicero, IL, this high-impact role blends business development with product strategy and development. Ideal candidates will thrive on building new categories and taking new products to market. You’ll lead business planning, support product development, and analyze market trends to expand sales across industrial and consumer sectors. To succeed, you’ll need hands-on business development experience and a track record of successful product launches, as well as strong execution, strategic thinking, and a willingness to travel. Ideal candidates enjoy building and launching new product strategies from the ground up and thrive in a hands-on, operations-driven environment. This is an exciting opportunity to shape a new product division from the ground up in a nimble and fast-moving environment with strong growth potential. Product Manager (Automotive Fluids/Chemicals; Business dev exp req) Responsibilities • Lead market analysis to identify opportunities and product segments, • Analyze sales performance and market trends to refine go-to-market strategies, • Translate category insights into executable product launch plans, • Collaborate on new product development with internal teams, • Partner with procurement to assess raw material needs, • Develop and execute business development strategy across B2B and retail channels, • Build go-to-market plans aligned with margin and cost targets, • Collaborate across marketing and sales for product rollout, • Travel nationally for product launches, trade shows, and meetings, • Execute margin strategy and cost analysis for product lines, • Guide regulatory and compliance steps for product approval Product Manager (Automotive Fluids/Chemicals; Business dev exp req) Qualifications • 5+ years of business development or product management experience required, • Experience launching new consumer products required, • Automotive fluids or chemical product knowledge required, • P&L and cost analysis experience required

#TeamNextdoor Nextdoor (NYSE: NXDR) is the essential neighborhood network. Neighbors, public agencies, and businesses use Nextdoor to connect around local information that matters in more than 340,000 neighborhoods across 11 countries. Nextdoor builds innovative technology to foster local community, share important news, and create neighborhood connections at scale. Download the app and join the neighborhood at ___. Meet Your Future Neighbors The Local Business team at Nextdoor is building the neighborhood engine for business growth. We connect neighbors and the local businesses around them through a cohesive ecosystem that spans free and paid experiences. This ecosystem includes the full journey for local businesses: from joining Nextdoor and setting up a high quality page, to earning neighbor trust through Faves, Mentions, and Recommendations, to scaling their success with paid offerings like Ads and Opportunity Alerts. On the neighbor side, we own how neighbors discover, evaluate, and engage with local businesses across core surfaces like Search, Faving, Recommending, Business Pages, notifications, and feeds. At Nextdoor, we offer a warm and inclusive work environment that embraces a hybrid employment model, blending an in office presence and work from home experience for our valued employees. The hiring team will go over these expectations with you if you are being considered for a role near one of our offices in San Francisco, Los Angeles, Chicago, Dallas, New York, and London. The Impact You’ll Make As a Product Manager on Local Business, you will build and own key aspects of this ecosystem, across both neighbor and business experiences and our paid offerings. You will be a generalist PM who can move across surfaces and product stages based on where the opportunity is greatest. Potential areas of ownership include: • Faves and the broader organic reputation system between neighbors and local businesses, • Neighbor-side discovery experiences such as Search, directories, and recommendation flows, • Business Pages, onboarding, and the business admin experience, • Paid products for SMBs like Opportunity Alerts, a neighbor <> business marketplace We will finalize your exact scope based on your experience, strengths, and the highest priority needs of the business. You will partner closely with Engineering, Design, Data Science, Operations, Product Marketing, and Comms, and you will work across consumer and SMB experiences. This role is remote in the US. Your responsibilities will include: If you are a systems thinker who loves data, can zoom between 0 to 1 and scale, and are comfortable rolling up your sleeves to unblock teams, this is the opportunity for you. In this role, you will: • Lead as the Product Owner for one or more Local Business domains across neighbor and business surfaces, from free value to paid offerings, • Build a clear vision, strategy, and roadmap for your areas that connects neighbor value, SMB outcomes, and revenue growth into coherent flywheels, • Design and run experiments across the funnel, using data and user insights to shape hypotheses, validate ideas quickly, and scale what works, • Translate complex systems into simple product experiences, using systems based thinking to map loops, dependencies, and constraints across Local Business, Ads, and Opportunity Alerts, • Ship both 0 to 1 products and meaningful improvements to existing flows, balancing speed and quality and sequencing work to learn fast while building durable foundations, • Work deeply with Data partners to define the metrics hierarchy for your areas, build tracking specs, and instrument end to end journeys across neighbor and business surfaces, • Partner closely with Operations to make sure launches are operationally sound and that we have the right playbooks and guardrails for scaled programs and marketplaces, • Collaborate with Product Marketing and Comms on narratives and GTM, especially for SMB and local business audiences who are new to Nextdoor or to our paid products, • Connect the dots across teams so Local Business, Ads, Opportunity Alerts, and core consumer experiences reinforce one another instead of competing, • Communicate clearly with executives and cross functional partners, bringing structure and clarity to ambiguous spaces and driving alignment on priorities, tradeoffs, and outcomes, • Obsess over the operational health of your products, proactively monitoring key metrics, digging into issues, and partnering with Engineering, Data, and Ops to keep the system healthy, • Participate in in person Nextdoor events, trainings, offsites, volunteer days, and other team activities that build relationships and contribute to the culture we value What You’ll Bring To The Team • 5+ years of product management experience in consumer or growth focused roles, with a track record of shipping impact in ambiguous environments, • Demonstrated success owning both 0 to 1 product builds and scaling or optimizing existing products, ideally across marketplaces, lead generation, or multi sided systems, • Required experience working with SMBs or local businesses, such as marketplaces for services, local commerce, or tools that help small businesses grow, • Required experience with subscription or recurring revenue products, including designing for retention, churn reduction, and lifetime value, • Preferred experience building or operating consumer facing products, including understanding engagement loops, retention drivers, and how to build products people use every day, • Strong data and experimentation mindset: comfortable working with data scientists and running experiments, defining success metrics, reading experiment results, and making decisions based on data, • Systems based thinking: ability to model complex ecosystems, identify flywheels, map out dependencies and failure modes, and design products that compound over time instead of creating one off wins, • Experience with marketplaces, lead products, or other multi sided systems is a strong plus, especially where managing supply, demand, and pricing are important, • Proven ability to work cross functionally with Engineering, Design, Data, Operations, Product Marketing, and Comms, and to drive alignment across teams without heavy process, • Comfort moving between strategy and execution: you can set a long term vision, then write clear PRDs, tracking specs, and launch plans and see them through, • Excellent written and verbal communication skills, including the ability to communicate clearly with senior executives, frame tradeoffs, and tell a compelling story grounded in data, • Natural ability to make things happen around you: you manage project ambiguity, complexity, and interdependencies in an organized and structured way, and are willing to roll up your sleeves to unblock the team, • Eagerness to explore and apply AI and emerging technologies to reimagine how work gets done Rewards Compensation, benefits, perks, and recognition programs at Nextdoor come together to create our total rewards package. Compensation will vary depending on your relevant skills, experience, and qualifications. The starting salary for this role is expected to range from $175,000 to $230,000 on an annualized basis, or potentially greater in the event that your 'level' of proficiency exceeds the level expected for the role. The salary range will be determined by the candidate’s geographic location. We expect to award a meaningful equity grant for this role. With quarterly vesting, your first vest date will take place within 3 months of your start date. When it comes to benefits, we have you covered! Nextdoor employees can choose between a variety of health plans, including a 100% covered employee only plan option, and we also provide a OneMedical membership for concierge care. At Nextdoor, we empower our employees to build stronger local communities. To create a platform where all feel welcome, we want our workforce to reflect the diversity of the neighbors we serve. We encourage everyone interested in our mission to apply. We do not discriminate on the basis of race, gender, religion, sexual orientation, age, or any other trait that unfairly targets a group of people. In accordance with the San Francisco Fair Chance Ordinance, we always consider qualified applicants with arrest and conviction records. For information about our collection and use of applicants’ personal information, please see Nextdoor's Personnel Privacy Notice, found ___. #LI-Remote

Thumbtack is the one app you need to take care of and improve your home — from personalized guidance to AI tools and a best-in-class hiring experience. Every day in every county of the U.S., people turn to Thumbtack to complete urgent repairs, seasonal maintenance and bigger improvements. We help homeowners know which projects to do, when to do them and who to hire from our growing community of 300,000 local service businesses. If making an impact inspires you, join us. Imagine what we’ll build together. The Accounting team partners across the business to ensure the accuracy, integrity, and transparency of our financial reporting. We play a critical role in capturing and recording company activity in real time, while maintaining strong controls and high standards, and providing financial insights to inform strategic decisions. Beyond compliance, we enable innovation by building scalable processes that support growth and evolving business models. As Director, Accounting, you will lead a team of 10 across the United States and the Philippines, overseeing General Accounting, Revenue Accounting, and Accounts Payable. You will partner closely with Finance, Procurement, Payroll, Legal, Tax, Product, and Engineering to ensure accurate reporting and scalable financial operations across the business. You and your team will build deep expertise in our products and revenue models, serving as the company’s accounting authority and guiding teams through complex and evolving transactions. You will play a key role in strengthening our processes and controls as we prepare for public-company readiness, helping scale the accounting function to support continued growth. This is an opportunity to make a meaningful impact at a high-growth company while building and shaping a best-in-class accounting organization. • Set and lead the multi-year strategy for Accounting, building a scalable operating model that supports company growth and public-company readiness., • Build and lead a high-performing team, developing managers, evolving org design, and strengthening leadership bench strength. Set performance expectations and foster a culture of accountability and continuous improvement., • Own the accuracy and timeliness of close processes, and other recurring and non-recurring accounting and A/P processes, continuously improving quality and performance metrics., • Identify opportunities to drive efficiency through streamlining processes or automating via accounting systems and workflows, particularly through use of AI., • Drive public-company readiness, strengthening internal controls, SOX compliance, and audit preparedness., • Partner on strategic initiatives, ensuring new products, revenue models, and partnerships are structured and operationalized in a scalable, compliant way., • 10 to 15+ years of experience, preferably including public accounting firm and publicly traded-company experience., • Experience leading teams, and preferably distributed and international teams, with a track record of building scalable, high-performing organizations., • Strong operational accounting experience, and driving process improvements including systems selection and implementation, and preferably a passion for AI and experience with Netsuite., • Strong understanding of internal controls, and SOX requirements., • US GAAP technical accounting fluency, and preferably a CPA., • Excellent communication (written and verbal), and passion for cross functional influencing., • A balance of operational rigor and strategic thinking, with the ability to scale processes for long-term success., • For candidates living in San Francisco / Bay Area, San Jose, New York City, or Seattle metros, the expected salary range for the role is currently $221,000.00 - $286,000.00., • For candidates living in Austin, TX or Washington DC metros or in California, Massachusetts, New Jersey, or Washington states, the expected salary range for the role is currently $198,900.00 - $257,400.00., • For candidates living in all other US locations, the expected salary range for this role is currently $187,900.00 - $243,100.00. Actual offered salaries will vary and will be based on various factors, such as calibrated job level, qualifications, skills, competencies, and proficiency for the role #LI-Remote Thumbtack embraces diversity. We are proud to be an equal opportunity workplace and do not discriminate on the basis of sex, race, color, age, pregnancy, sexual orientation, gender identity or expression, religion, national origin, ancestry, citizenship, marital status, military or veteran status, genetic information, disability status, or any other characteristic protected by federal, provincial, state, or local law. We also will consider for employment qualified applicants with arrest and conviction records, consistent with applicable law. Thumbtack is committed to working with and providing reasonable accommodation to individuals with disabilities. If you would like to request a reasonable accommodation for a medical condition or disability during any part of the application process, please contact: ___. If you are a California resident, please review information regarding your rights under California privacy laws contained in Thumbtack’s Privacy policy available at ___. We put as much craftsmanship into candidate safety as we do into the hiring experience itself. While scammers may try to impersonate our team, we’ll never ask you for money, banking info, or SSNs during hiring. ___