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Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply. The Opportunity The Executive Assistant will provide executive, operational, and administrative support to the CHRO and CTOO. Responsibilities include managing complex schedules, coordinating meetings and travel, supporting department budgets and vendor activities, facilitating employee engagement initiatives, and partnering across the organization to ensure smooth day-to-day operations. Responsibilities Executive Support Provide high-level administrative support to the CHRO and CTOO. Manage complex calendars, schedules, and meeting logistics across multiple stakeholders and time zones. Coordinate domestic and international travel arrangements, itineraries, and expense reporting. Prepare meeting materials, presentations, agendas, and executive communications. Anticipate executive needs, proactively manage priorities, and ensure timely follow-up on key actions. Handle highly confidential information with professionalism and discretion. Human Resources, Technical Operations & Employee Experience Support employee engagement and culture-building initiatives across the organization. Coordinate logistics and execution for Exchange Meetings, Anchor Weeks, employee recognition activities, leadership meetings, and company-wide events. Maintain HR-related communications, resources, and administrative processes. Coordinate vendor and contract administration activities for both Human Resources and Technical Operations, including purchase order management, invoice processing, contract routing, and maintaining related documentation within company systems. Support department budget administration and vendor relationships. Collaboration & Office Support Partner closely with the Executive Administration team to ensure seamless support across the organization. Collaborate on company events, leadership meetings, and special projects. Participate in regular onsite activities in the Cambridge office, including team meetings, employee engagement events, onboarding activities, and other key business initiatives, helping to foster a connected and collaborative workplace culture. Help foster a welcoming, professional, and collaborative workplace environment. Required Qualifications 10+ years of Executive Assistant or senior administrative support experience, preferably supporting senior leaders. Exceptional organizational, planning, and prioritization skills. Strong written and verbal communication skills. Demonstrated ability to manage multiple priorities in a fast-paced environment. Advanced proficiency in Microsoft Office Suite. Proven ability to manage confidential and sensitive information with discretion. Preferred Requirements Experience in biotechnology, pharmaceutical, healthcare, or other highly regulated industries. Experience with purchase order processing, invoice management, vendor administration, and systems such as LinkSquared, Workday, Concur, NetSuite, or similar business applications. Bachelor's degree or equivalent combination of education and experience. Work Location and Conditions • At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee., • You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested., • You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location. Compensation The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity. Estimated Pay Range $120,000 - $135,000 USD To stay connected with us, follow Amylyx Pharmaceuticals on _. To return to our website please _. Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Executive Assistant to the Founder & CEO Location: UK – Hybrid / Flexible Working Contract: Permanent | Full-time Thomas & Co International is a growing, multi-award-winning tax and advisory firm supporting entrepreneurs, privately owned businesses, high-net-worth individuals and internationally mobile clients across the UK and overseas. The firm has doubled revenue for four consecutive years and now operates with a team of 35+ high performers. As the firm continues to scale, we are looking for an exceptional Executive Assistant to provide direct, high-trust support to our Founder & CEO. This is a senior support role for someone exceptional at managing complexity, anticipating needs and operating with absolute discretion. The successful candidate will work as the Founder’s right hand across the full spread of his commercial, content and personal commitments. Our Founder & CEO Josh Thomas was recently named in the Forbes 30 Under 30 Europe list in the Finance category. He has built one of the largest personal brands in the tax advisory space, reaching millions of views each month and landing him in entrepreneurial circles out of reach to most. You can explore his thought leadership and insights via his _. The Role This role provides direct, comprehensive support to the Founder across the full spread of his commercial and personal commitments. You will own his diary, travel and communications, coordinate across the firm’s commercial workstreams and content production, and act as a trusted gatekeeper for his time and standards. On any given week, you may be coordinating complex international travel, preparing briefing notes for a high-net-worth client meeting, supporting a podcast or speaking engagement, liaising with editors on content campaigns, and managing inbound requests from media, partners and prospective clients. The work spans operational, strategic and personal, and requires someone who can hold all of it with discretion, polish and pace. Key Responsibilities: • Own and manage the Founder’s diary, ensuring time is allocated effectively across commercial, content, partnership and personal commitments., • Coordinate complex domestic and international travel, including flights, accommodation, ground transport and full itineraries., • Manage inbound communications, prioritising correspondence and acting as a first-line filter for the Founder’s time., • Prepare for meetings, including agendas, briefing notes and supporting documents, and ensure agreed actions are tracked through to completion., • Coordinate across internal team members and external partners to keep commercial workstreams progressing on the Founder’s behalf., • Act as a key point of contact for high-profile clients, partners and brand collaborators, representing the Founder’s standards in every interaction., • Support the Founder’s content and personal brand operation, coordinating with editors, podcast hosts, event organisers and partnership brands., • Manage personal commitments, lifestyle administration, restaurant and event bookings, and ad-hoc personal tasks., • Maintain absolute discretion across all confidential business and personal information at all times. Experience and Qualifications: • Significant experience as an Executive Assistant or Chief of Staff to a Founder, CEO or senior public-facing executive., • Track record supporting a Founder or principal who attracts inbound media, podcast, public speaking and investment opportunities is highly advantageous., • Highly commercially aware, with the capability to act and operate on the Founder’s behalf in commercial conversations and inbound opportunity discussions., • Demonstrated ability to manage complex domestic and international diary and travel logistics with precision., • Experience operating within high-net-worth, professional services or comparable environments such as luxury, finance or talent management is highly advantageous., • Confident handling sensitive and confidential information with absolute discretion., • Excellent written communication, with strong drafting and proofreading skills., • Highly proficient with diary, productivity and project management tools (Google Workspace, Slack, Asana or equivalent)., • Comfortable coordinating with content production teams (editors, videographers, podcast hosts) is advantageous., • Willingness to travel domestically and internationally as required, including to the Founder’s overseas base., • Willingness to flex working hours where required to support the Founder’s schedule, with appropriate boundaries respected. Personal Qualities: • Highly polished, professional and well-presented, with the ability to represent the Founder and the firm to an exceptional standard., • Anticipatory by nature, with a strong instinct for what the Founder needs before being asked., • Calm and composed under pressure, with the resilience to manage competing priorities and last-minute changes., • Discreet, trustworthy and committed to absolute confidentiality., • Strong judgement, comfortable making decisions on the Founder’s behalf where appropriate., • Excellent communicator, both written and verbal., • Genuinely committed to enabling the Founder to operate at his highest level. What We Offer A highly competitive remuneration package designed to recognise both individual contribution and collective team success. Our approach combines financial reward, career progression and personal wellbeing to support our people in continued growth and development. Joining us means working directly alongside one of the most recognisable founders in UK tax advisory, with full visibility of the commercial, content and brand operation that has built Thomas & Co International into the firm it is today. We measure contribution, not just length of service. If you are looking for a role with genuine pace, real proximity to decision-making and the chance to enable a high-profile founder to operate at his absolute peak, then Thomas & Co International is your calling. Benefits Package: • Highly competitive base salary., • Wellness subscription., • Life assurance cover., • An additional day’s leave for your birthday, plus a holiday buy-back scheme., • Hybrid and flexible working arrangements., • Direct daily proximity to senior leadership and decision-making., • Clear opportunity for career progression in a fast-growing firm. We are an equal opportunities employer and welcome applications from all backgrounds. Applicants must have the right to work in the UK, as visa sponsorship is not available for this role.

Also known as: Media buyer, TV, radio or digital buyer, out of home buyer Media buyers book advertising space in newspapers and magazines, and on TV, radio and the internet. • identify the target audience and decide how to reach them through advertising, • keep up with industry research into people’s lifestyles, • build relationships with clients and media sales companies, • negotiate for the most suitable advertising spots at the best rates, • prepare costings for clients, • analyse sales data, to judge a campaign’s effectiveness You could work in an office or at a client’s business. You could work in an office or at a client’s business. You may need to wear smart business dress. 38 to 40 hours per week 9am to 5pm • knowledge of media production and communication, • the ability to use your initiative, • the ability to organise your time and workload, • patience and the ability to remain calm in stressful situations, • to be thorough and pay attention to detail, • to be flexible and open to change, • the ability to come up with new ways of doing things, • to be able to use a computer and the main software packages competently You can get into this job through: • a university course, • working towards this role, • specialist courses run by professional bodies You could do a related apprenticeship like an assistant buyer higher apprenticeship or an advertising media executive advanced apprenticeship. With experience these may give you some of the skills, knowledge and industry contacts you need to move into advertising media buying roles. You'll usually need: • 5 GCSEs at grades 9 to 4 (A* to C), or equivalent, including English and maths, for an advanced apprenticeship, • 4 or 5 GCSEs at grades 9 to 4 (A* to C) and A levels, or equivalent, for a higher or degree apprenticeship, • You'll find it useful to get experience to help you understand the industry and to meet people who may help you find paid work. You could try: work experience; internships; temporary employment, • You could contact agencies directly to ask about placements, and make industry contacts through social networking sites like Twitter or LinkedIn., • You could start in a junior position like office assistant in a small advertising agency and work your way up through training and promotion., • You could study the Foundation Certificate offered by the Institute of Practitioners in Advertising if you have less than a year’s experience in an advertising, marketing or communications role., • You might choose to specialise in buying radio, online or television advertising., • You could eventually become a media manager of an agency, or move into media planning, account planning or account management. #J-18808-Ljbffr

An award-winning global luxury brand is searching for an exceptional Executive Assistant to support its Founders. This is a pivotal, high-trust role for someone who is effortlessly organised, naturally proactive, and thrives in a fast-moving, creative environment where details matter and standards are high. Working at the very heart of a leading design studio, you’ll ensure the Founders’ time, focus, and energy are protected and prioritised. From managing complex schedules and international travel to acting as a central point of coordination across the studio, you’ll be a true right hand — enabling creativity, strategy, and client relationships to flourish. • Managing complex diaries, meetings, and international travel across multiple time zones., • Preparing research, briefings, and polished client-facing materials., • Acting as a gatekeeper for communications, always with discretion and professionalism., • Coordinating internal schedules, resources, and key project milestones., • Supporting proposals, presentations, and core studio documentation., • Assisting with events, logistics, and occasional personal administration when required., • 3–5+ years’ experience supporting senior leaders within creative, luxury, or fast-paced business environments., • Calm under pressure, intuitive, and emotionally intelligent — always thinking one step ahead., • An excellent communicator with outstanding organisational and multitasking skills., • Tech-savvy and confident using modern productivity and collaboration tools., • Discreet, dependable, and deeply aligned with values of creativity, excellence, and precision., • Work closely with visionary founders in a globally recognised luxury brand., • Be embedded in a world-class creative studio where your contribution truly matters., • A role built on trust, influence, and long-term impact., • Exposure to international clients, projects, and creative leadership. Mid-Senior level Full-time Administrative Marketing Services #J-18808-Ljbffr

The Shelburne Hospital in Great Missenden, part of Circle Health Group, is seeking an Executive Assistant to support the Senior Management Team.The role covers diary management, communications, governance support, and meeting administration across cross-site requirements.Chiltern Hospital when neede