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At GSK we are looking for a highly capable senior technical builder who can design and govern the data-flows that GSK’s Research & Development (R&D) division runs on. If you believe data should move on its own and still arrive trusted, then this role could be for you.The Data Flow Lead role reports directly into the Senior Director for Data Governance, Innovation & Automated Compliance, and sits within the Data Value Office (DVO) for the Chief Medical Officer (CMO) organization of GSK’s Research & Development (R&D) function.This role is focused on delivering data-flows-as-product, compliance-as-code, and governance built into the pipeline (instead of bolted-on). Take the next step in your career now, scroll down to read the full role description and make your application. You will turn scattered systems and sources into modular, reusable, end-to-end flows in one consistent format that can be used to its full potential throughout GSK’s R&D divisions. Your mission is to make R&D data visible, trusted and automation-ready (by default) so teams can decide faster and scale agentic solutions with confidence (whilst keeping the human expert in the loop).Key Responsibilities (include..):Manage the development of business requirements for data-flow (through collaboration with R&D business/functional leads and data platform colleagues) to translate business needs into technical data requirements and processes to ensure seamless data-flow integration and usage across the R&D ecosystem.Design, develop and maintain modular, end-to-end data-flows (spanning roles, interfaces, data and metadata, triggers and access) to integrate systems and data sources into trusted, reusable assets across R&D (including writing clean, readable code where required).Ensure data-flows support compliance-by-design; integrating, contextualising and orchestrating data and systems in line with compliance principles.Deliver pre-packaged, curated data-flows aligned to business requirements, which include documented data specifications describing processing steps required to generate each flow.Integrate diverse data-flows (eg; protocol development, Development Safety Update Report (DSUR) and clinical trial Individual Human Data (IHD)) into a unified machine readable format for consistent implementation and an end-to-end data ecosystem.Ensure deliverables are appropriately quality controlled, documented and, where required, able to be handed over to function leads and the R&D Tech team for scale implementation. This extends to quantifying and providing insights into business impact and value creation arising from data-flow activities.Coaching and peer review to ensure the team's work reflects industry best practice for data-flow creation activities, including data standards.Location: GSK HQ London, Stevenage, or Ware R&D.Please Note: If the successful applicant is based at Stevenage site: This role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge UK, in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.About You:Please note that this role is not a documentation role. We are looking for a capable technical subject matter expert with experience of delivering sophisticated date-flow solutions. You will be confident with metadata ecosystems and agentic workforces (and related agentic decision-making processes). We are currently operating with Azure (but applicants with experience of similar systems are encouraged to apply, including GCP). As this role is multi-faceted and includes collaborating / liaising with a wide variety of stakeholders and matrix teams you must have strong experience of working in complex matrix-environment, with demonstrable clear problem-solving approach to your work.About GSK:At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together. Find out more • our approach to R&D: APPLICATION CLOSING DATE – Monday 9th of November 2026 (COB).Basic Qualifications:Relevant degree-level education (eg; BS/MSc/PhD (or equivalent) in Computer Science, Mathematics, Statistics or a related subject).Relevant experience / knowledge of translating business needs into technical data requirements and processes, ability to quantify and provide insights into business impact and value creation from data-flow activities, and handling complex data-flow processes efficiently.Knowledge / experience of metadata ecosystems and agentic solutions.Relevant hands-on experience with policy engines, including translating governance requirements into practical, executable Policy as Code.Relevant experience in integrating multiple data sources and systems into unified reusable data-flows ( whilst ensuring data privacy and compliance-by-design).Proficiency with a range of digital tools (eg; Auzure, GCP) and experience leveraging AI or digital technologies to improve efficiency or insights.SkillsArtificial Intelligence (AI), Computational Sciences, Computer Programming, Data Analysis, Data Management, Data Modeling, Data Science, Predictive Modeling, Statistical ModelsWhy GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receiveImportant notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: UK – London – New Oxford Street; UK • Hertfordshire, • Stevenage; UK, • Hertfordshire, • Ware RDType: Full time

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage, UK. Please make an application promptly if you are a good match for this role due to high levels of interest. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.Director, Oncology Translational Medicine, Clinical BiomarkersJob Purpose:The Director, Oncology Translational Medicine, Clinical Biomarkers is responsible for the development and effective implementation of biomarker and translational medicine strategies to support the clinical development of late-stage oncology assets.As a key member of a Clinical Matrix Team (CMT), the Clinical Biomarker Director will collaborate with the Clinical Biomarker Executive Director to establish clear decision-making criteria, define patient segmentation strategies, and integrate these into clinical development plans.You will leverage cutting-edge technologies and methodologies to discover and clinically validate biomarkers, ensuring the biomarker strategy is fully aligned with the clinical plan. This integration will optimise decision-making in drug development and enable the identification of the right patient populations for our medicines.Key responsibilities:Collaborating closely with the Clinical Biomarker Executive Director to drive the design, alignment, and execution of clinical biomarker and translational medicine strategies focused on identifying predictive biomarkers that enable clinical success.Validating and implementing biomarker strategies, including target engagement, pharmacodynamic, and proof-of-mechanism biomarkers, for clinical-phase programs to support patient stratification, dose selection, and enable clinical go/no-go decisions.Participating in tumor-specific Biomarker Matrix teams, with responsibility for executing clinical biomarker strategies for late-stage oncology programs, while working closely with internal and external stakeholders, as well as disease area strategy teams.Representing Translational Medicine at Clinical Development Matrix Teams (CMT) to establish biomarker-driven decision-making criteria and their seamless integration into clinical study designs, aligning with clinical study objectivesSupporting disease area strategies and translational objectives by defining biomarker priorities, areas of interest, and generating decision-enabling evidence packages informed by real-world datasets, internal and external data and partnerships (For e.g., research collaborations, KEE consultations).Identifying cutting-edge science and technological advances to incorporate into biomarker strategies for guiding indication selection, patient enrichment, and combination strategies.Overseeing and/or developing sample testing plans and delivering high-quality biomarker data packages to inform clinical development and regulatory strategies.Managing effective relationships with clinical and scientific operations, diagnostics, medical science, medical affairs, regulatory, portfolio management, and commercial functions.Supporting the expansion of mechanism and disease understanding to generate insights for indication expansion and scientific exchange as needed.Defining and studying mechanisms of resistance to enable reverse translation, inform next-line strategies, support patient enrichment, and influence life cycle management of assets.Contributing to the company’s scientific credibility through publications and presentations.Why You?Basic Qualifications:We are looking for professionals with the following required skills and experience:Ph.D. or equivalent with 7+ years or M.Sc. with 10+ years of drug development experience in the pharmaceutical industry, with a solid background in Oncology clinical biomarkers, expertise in late-phase oncology studies, and translational research within clinical development.Strong expertise in cancer biology, and clinical development, including the therapeutic landscape, approved and investigational agents, and diagnostic approaches in solid tumor and haematological malignancies.Experience in leading cross-functional teams and designing and executing strategic biomarker plans including development of regulated biomarker assays.Experience conducting clinical trials and working as part of clinical study teams.Experience designing and executing translational biomarker plans for clinical trials. Explores and onboards innovative technologies to advance translational research and new biomarker developmentExperience collaborating effectively with Data Sciences to analyze high-dimensional preclinical and clinical data to guide clinical decisions and inform asset strategy.Hands-on experience implementing a broad range of biomarker platforms such as flow cytometry, molecular diagnostics including NGS, FISH and PCR, IHC/IF, liquid biopsy / ctDNA approaches, and multi-omic biomarker analyses.undefinedDirect successful translation of pre-clinical research to human clinical trials, leveraging learnings from genomic, transcriptomic, and proteomic analyses of both preclinical models and patient samples.Experience influencing teams and key leaders, with a track record of success.Preferred Qualifications:The following qualifications would be advantageous:M.D., Ph.D. or equivalent doctoral degree in a relevant scientific discipline.Experience with high-dimensional dataset analysis.Prior experience with diagnostic development and regulatory interactions.Experience with digital pathology, AI/ML-enabled biomarker analyses, external scientific partnerships, and mentoring or developing scientific colleagues.Strong sense of urgency and excellent skills in prioritization, planning as well as timely execution in a very fast-paced environmentStrong interpersonal skills and ability to thrive in a matrixed environment. Dependable and trustworthy, willing to take ownership and responsibilityExcellent communication, problem-solving, matrix project-management, and presentation skills.LI-GSK *LI-Hybrid *SkillsAnalytical Thinking, Clinical Data Interpretation, Clinical Data Review, Clinical Development, Clinical Trial Designs, Clinical Trials Monitoring, Digital Fluency, Drug Regulatory Affairs, Executive Presence, Hematology and Oncology, Learning Agility, Matrix Leadership, Real World Evidence (RWE), Scientific Presentations• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $189,750 to $316,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: USA • Pennsylvania, • Upper Providence; GSK HQ; UK, • Hertfordshire, • Stevenage; WalthamType: Full time

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. Be one of the first applicants, read the complete overview of the role below, then send your application for consideration. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.The Senior Medical Director, Oncology Clinical Development – Sarcoma, is a senior physician leader within the clinical programme team, providing medical oversight, strategic clinical insight, and a patient-centred perspective across the design, conduct, and interpretation of clinical studies. This role ensures that medical considerations, patient safety, and clinical integrity are consistently applied across studies within a programme.Operating within the clinical strategy defined by the Clinical Development Lead (CDL), the Senior Medical Director partners closely with the Senior Scientist and cross-functional teams to guide the integration of physician expertise into study execution and programme-level decision-making. The role serves as a senior member of the Clinical Matrix Team (CMT), contributing to complex clinical decisions, regulatory interactions, and external scientific engagement.The Senior Medical Director provides matrixed oversight to the clinical team within the programme, supporting consistency of clinical judgement, safety evaluation, and medical interpretation across studies.PLEASE NOTE: This career opportunity requires an on-site office presence (minimum of two days a week) at one of GSK’s Switzerland (Zug), UK (Stevenage or London HQ) or US (PA or MA) sites.In This Role You Will:Serve as a senior physician leader within the clinical programme, providing medical oversight and clinical insight across study design, conduct, and data interpretationProvide guidance on medical monitoring and safety oversight across studies, ensuring consistent application of clinical judgement and patient safety standardsInterpret complex clinical and safety data, generating insights that inform programme-level decisions led by the CDLPartner with the Senior Scientist and cross-functional teams to ensure medical considerations are integrated across study execution and programme deliveryProvide senior medical input into protocol development and study design, ensuring clinical relevance and patient-centred design within the clinical strategy defined by the CDLServe as a senior member of the CMT, influencing study-level and programme-level decision-makingEngage with investigators, Key External Experts (KEEs), and scientific leaders to support external engagement and represent the programme at advisory boards, steering committees, and scientific forumsProvide medical guidance and mentorship to Medical Directors within the programme, supporting consistency and development of clinical capabilityDetailed Responsibilities:Medical Monitoring and Safety Oversightconsistency in approach, patient safety, and protocol adherenceGuide interpretation of safety data in collaboration with pharmacovigilance, supporting signal detection, escalation, and benefit–risk evaluation across the programmeParticipate in and contribute to safety review forums (e.g., SRT, IDMC), providing senior physician perspective on complex safety questionsEnsure medical monitoring approaches are aligned across studies and consistent with regulatory and organisational standardsStudy Design and ExecutionProvide senior medical input into protocol development across studies, ensuring clinical relevance, feasibility, and alignment with the clinical strategy defined by the CDLGuide clinical aspects of study design and protocol implementation, particularly for complex, high-risk, or multi-study programmesSupport resolution of complex medical questions arising during study conduct, applying clinical judgement to inform programme-level decision-makingEnsure consistency of medical considerations across multiple studies within the programmeData Interpretation and Scientific ContributionInterpret complex clinical data across studies, integrating findings to inform programme-level insights on safety, efficacy, and patient impactContribute to programme-level data interpretation and support CDL-led benefit–risk assessment and clinical positioningGuide development of scientific communications, including publications, congress materials, and clinical summariesMaintain deep understanding of disease biology, evolving treatment paradigms, and competitive landscape to inform clinical interpretation and programme strategyRegulatory and External EngagementContribute senior medical expertise to regulatory interactions and Health Authority discussions, including responses to complex clinical and safety queriesRepresent the programme at advisory boards, steering committees, and external scientific forums, providing senior physician perspective on clinical data and programme directionEngage with KEEs and scientific collaborators to support programme development, scientific exchange, and external credibilityLead or contribute to the clinical and technical diligence assessment of business development opportunitiesCross-Functional Collaboration and Clinical Matrix TeamServe as a senior member of the Clinical Matrix Team (CMT), influencing cross-functional alignment and programme-level decision-makingContribute medical expertise to disease area strategy, integrated evidence planning, and Medical Affairs discussionsCollaborate across functions to ensure alignment on safety, data interpretation, and clinical positioning across the programmeLead or contribute to Oncology Clinical Development-wide initiatives and workstreamsPeople Leadership & Capability DevelopmentProvide oversight, guidance, and mentorship to clinical scientists within the programme, supporting consistency and quality of medical input across studiesSupport development of clinical capability within the medical team, including coaching on medical monitoring, data interpretation, and external engagementContribute to talent development, performance discussions, and capability building within Oncology Clinical DevelopmentBasic Qualifications:Medical degree and completion of advanced specialty training, fellowship or country-equivalent higher-level qualification in medical oncology, pediatric oncology or hematology.Experience in sarcoma oncology, including leading drug development.Clinical and pharmaceutical experience in oncology clinical development, with depth across multiple studies or programmesExperience in medical monitoring, safety evaluation, and clinical data interpretation across clinical studiesUnderstanding of clinical development processes, GCP, ICH guidelines, and global regulatory frameworksExperience operating within cross-functional matrix teams and contributing to complex clinical and programme-level decisionsPreferred Qualifications:Deep expertise in soft tissue sarcoma and osteosarcoma, including experience leading or supporting clinical development programs across early and/or late-stage clinical studies.Strong scientific communication and stakeholder engagement skills, with the ability to influence internal and external audiencesDeep experience in oncology clinical development across multiple studies or programmes, including Phase I–IIIExperience contributing to or leading aspects of regulatory interactions (e.g., IND, scientific advice, NDA/MAA)Demonstrated experience engaging with KEEs, advisory boards, and scientific communities in oncologyTrack record of scientific publications and congress presentationsDeep understanding of oncology disease biology and the evolving treatment landscape across solid tumours and/or haematological malignanciesExperience contributing to clinical and technical diligence for business development opportunities#ESMO2026SkillsClinical Data Interpretation, Clinical Pharmacology, Clinical Trial Designs, Clinical Trials Monitoring, Digital Fluency, Drug Development, Drug Regulatory Affairs, Evidence Based Decision Making, Executive Presence, Hematology and Oncology, Learning Agility, Matrix Leadership, Real World Evidence (RWE), Scientific Presentations, Strategic Direction• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $284,250 to $473,750. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receiveImportant notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: UK – London – New Oxford Street; USA • Massachusetts, • Waltham; UK, • Hertfordshire, • Stevenage; Switzerland, • Zug; USA, • Pennsylvania, • Upper ProvidenceType: Full time

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. Submit your CV and any additional required information after you have read this description by clicking on the application button. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.Find out more:Our approach to R&DWe are seeking an experienced Medical Director Clinical Development- Respiratory to join GSK’s Respiratory, Immunology & Inflammation Research Unit. In addition to providing clinical and scientific leadership to clinical and translational studies or programs for asset-level projects, you will contribute to the assessment of potential mechanisms and targets, target validation programs, life-cycle expansion, and innovative clinical development opportunities. You will work cross-functionally to develop and execute clinical development plans (CDPs) and contribute to above-project development of foundational and real-world data, and translational and biomarker capabilities, within a department that prioritizes understanding mechanism and unmet need alongside innovative clinical development, helping us deliver differentiated medicines that change the course of disease and improve patients’ lives.In the Respiratory, Immunology, and Inflammation Research Unit (RIIRU), our enduring purpose is to leverage immune science to address underlying organ dysfunction and disease. We are trailblazing a pipeline of medicines to dramatically improve how we cure and care for patients. We are a diverse team of industry-leading experts who channel our passion for scientific exploration into true value for patients and GSK. We drive the end-to-end R&D journey, fueling early discovery and our mid-stage pipeline while also advancing our late-stage medicines to launch. We are combining field-leading data sets, capabilities, and methods with decades of knowledge, to transform our success in how we innovate new medicines.Working model:This role is hybrid. You will be on-site at one of the posted locations at least two days per week. Remote work is available on other days.Position Summary:This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:Support alignment of translational and clinical plans and study designs with project strategies to ensure quality design and execution of the CDP. Develop sections of core regulatory documents.Generate the data and evidence required to determine a target’s potential efficacy, safety profile, key areas of differentiation and route to becoming a medicine with value to patients in the shortest possible timeframe.Define and deliver the clinical pillars of the translational table.Deliver clinical development and study timelines and endpoints, including pharmacology, mechanism, and clinical efficacy endpoints, enabling key decision points and Go/No Go criteria for the CDPEstablish and maintain relationships with program counterparts in Biology, Translational Sciences, Commercial, Regulatory, Clinical Operations, Market Access, Medical Affairs and Statistics.Contribute to the implementation and embedding of strategic initiatives and various organizational initiatives in Clinical Development.Clinical Development Strategy and Study & Program Design Provide effective support and oversight of R&D evidence generation strategy, plan, and activities to ensure patient safety and on-time, in-full study delivery. Contribute to the study team discussions on indication planning and incorporate input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc.) to contribute to vital deliverables including early medicine profile, target validation, translational plans, candidate selection.Design clinical development plans, study protocols, and associated documents across all phases of development, reflecting internal and external stakeholder input (e.g., patients, evidence generation, regulators, payors, pharmacovigilance).Bring clinical expertise to regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.Provide medical monitoring and oversight of the safety of study participants on behalf of the Sponsor during the study, together with Pharmacovigilance Physician.Accountable for medical governance across the project to ensure scientific integrity and overall safety of the study subjects across the study.Clinical Leadership Accountable for leading the Clinical Matrix Team (CMT) for a program. Serves as a clinical point of contact both internally and externally for an indication of an asset or for a clinical study. Represents the CMT at Early/Medicine Development Teams or clinical study at CMT.Actively leads the end-to-end clinical development strategy for an early program and may contribute to later stages.Serve as the primary Clinical point of contact for an investigational agent (early development) or clinical study for internal and external stakeholders, including regulatory agencies, key opinion leaders, and clinical investigators and with the relevant internal review boards (e.g., Technical Review or Governance) and/or Protocol Review Board.Assist with clinical evaluation of business development opportunitiesStay abreast of advancements in research, clinical trial methodologies, competitive environment, and regulatory space in the relevant disease area to maintain GSK’s competitive edge.Identify and highlight transformational opportunities, where projects can offer highly significant benefit to patients in ways not possible with existing approaches.Gather and supports the integration of inputs from across disciplines (scientific, clinical commercial, regulatory) to contribute to clinical components of the Medicine Profile (MP).Consistently contribute to solving study and overall clinical development challenges.Demonstrate ability to influence others at project, departmental and inter-departmental levels, as appropriateCreating Innovative Scientific and Technical SolutionsEmbrace challenge as an opportunity for creativity and use new learning and digital tools to create innovative approaches to science and technical solutions.Promote an environment for others to generate ideas for improvement and proactively drives innovation, beyond taking advantage of opportunities that arise.Influencing and Inspiring Others and Managing Conflict Consistently achieves desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support.Able to consistently inspire others by setting a positive example, communicating a compelling vision, and creating an environment where team members feel valued and motivated.Manage conflicts effectively and independently, negotiating mutually acceptable solutions.Enterprise Mindset, Strategic Thinking and Navigating Ambiguity Demonstrate enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.Analyzes, interprets and critically evaluates data, information, and digital content to interpret complex information, anticipate obstacles and identify potential solutions.Demonstrate flexibility and adaptability in changing environments, able to analyze incomplete information, identify potential risks and implications, and make informed decisions.Why You? Basic Qualifications:We are looking for professionals with these required skills to achieve our goalsMedical DegreeCompletion of a formal postgraduate clinical training, clinical residency or specialty training in Internal Medicine, Pathology, etcDemonstrated experience in clinical trial conduct, including medical monitoring, safety review, and clinical data interpretationStrong working knowledge of clinical development processes, including GCP, ICH guidelines, and global regulatory frameworks Ability to apply clinical judgement to support study design, patient safety, and real-time medical decision-making within a structured clinical development framework Experience operating effectively within cross-functional matrix teams in a pharmaceutical, biotechnology, or academic clinical trial environment Strong scientific communication skills, with the ability to translate clinical data into clear insights for internal and external audiencesPreferred Qualifications: In addition to the above, you will stand out if you bring the followingCompletion of advanced specialty training, fellowship or country-equivalent higher-level qualification leading to recognition as a medical specialist through formal certification, board certification, or country specific professional designationRobust knowledge of pulmonary hypertension research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution highly preferredExperience in pharmaceutical or biotechnology clinical development across early phase studiesClinical experience in relevant specialty and/or relevant therapeutic areas, with direct exposure to clinical research or drug development in industry or postgraduate workKnowledge of and experience in the execution of clinical and/or translational studies including generation and analysis of human translational data and conduct of preclinical biological experiments in relevant model systems.Experience working with global regulatory agencies and managing global clinical trials in relevant disease areaPrior experience contributing to regulatory interactions (e.g., IND submissions, scientific advice, NDA/MAA filings)Demonstrated experience engaging with Key External Experts (KEEs), investigators, and scientific collaborators in aging disease areasDemonstrated ability to work collaboratively in cross-functional teams and a matrix environment to design and execute trials to regulatory standards.Experience in contributing to IND/CTA, NDA, BLA, or MAA submissionsSkillsClinical Development, Communication, Drug Regulatory Affairs, Evidence Based Decision Making, Good Clinical Practice (GCP), Influencing Without Authority, Learning Agility, People Management, Project Management, Scientific Presentations, Strategic Thinking• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $222,750 to $371,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receiveImportant notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: UK • London; USA, • Massachusetts, • Waltham; UK, • Hertfordshire, • Stevenage; Stevenage; USA, • Pennsylvania, • Upper ProvidenceType: Full time

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. Want to apply Read all the information about this position below, then hit the apply button. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.Cancer is unrelenting, but so are we. At GSK, we are committed to transforming outcomes for people with cancer through innovative science, bold ambition, and strong partnerships across the healthcare ecosystem. We focus our science where it can matter most — advancing care in cancers with high unmet need, grounded in a deep understanding of disease biology and deliberate scientific choices that connect discovery to meaningful impact in the real world.The Senior Medical Director, Oncology Clinical Development • Lung is a senior physician leader within the clinical programme team, providing medical oversight, strategic clinical insight, and a patient-centred perspective across the design, conduct, and interpretation of clinical studies. This role ensures that medical considerations, patient safety, and clinical integrity are consistently applied across studies within a programme.Operating within the clinical strategy defined by the Clinical Development Lead (CDL), the Senior Medical Director partners closely with the Senior Scientist and cross-functional teams to guide the integration of physician expertise into study execution and programme-level decision-making. The role serves as a senior member of the Clinical Matrix Team (CMT), contributing to complex clinical decisions, regulatory interactions, and external scientific engagement.The Senior Medical Director provides oversight and guidance to Medical Directors within the programme, supporting consistency of clinical judgement, safety evaluation, and medical interpretation across studies.PLEASE NOTE: This career opportunity requires an on-site office presence (minimum of two days a week) at one of GSK’s Switzerland (Zug), UK (Stevenage or London HQ) or US (PA or MA) sites.In This Role You Will:Serve as a senior physician leader within the clinical programme, providing medical oversight and clinical insight across study design, conduct, and data interpretationProvide guidance on medical monitoring and safety oversight across studies, ensuring consistent application of clinical judgement and patient safety standardsInterpret complex clinical and safety data, generating insights that inform programme-level decisions led by the CDLPartner with the Senior Scientist and cross-functional teams to ensure medical considerations are integrated across study execution and programme deliveryProvide senior medical input into protocol development and study design, ensuring clinical relevance and patient-centred design within the clinical strategy defined by the CDLServe as a senior member of the CMT, influencing study-level and programme-level decision-makingEngage with investigators, Key External Experts (KEEs), and scientific leaders to support external engagement and represent the programme at advisory boards, steering committees, and scientific forumsProvide medical guidance and mentorship to Medical Directors within the programme, supporting consistency and development of clinical capabilityDetailed Responsibilities:Medical Monitoring and Safety Oversightconsistency in approach, patient safety, and protocol adherenceGuide interpretation of safety data in collaboration with pharmacovigilance, supporting signal detection, escalation, and benefit–risk evaluation across the programmeParticipate in and contribute to safety review forums (e.g., SRT, IDMC), providing senior physician perspective on complex safety questionsEnsure medical monitoring approaches are aligned across studies and consistent with regulatory and organisational standardsStudy Design and ExecutionProvide senior medical input into protocol development across studies, ensuring clinical relevance, feasibility, and alignment with the clinical strategy defined by the CDLGuide clinical aspects of study design and protocol implementation, particularly for complex, high-risk, or multi-study programmesSupport resolution of complex medical questions arising during study conduct, applying clinical judgement to inform programme-level decision-makingEnsure consistency of medical considerations across multiple studies within the programmeData Interpretation and Scientific ContributionInterpret complex clinical data across studies, integrating findings to inform programme-level insights on safety, efficacy, and patient impactContribute to programme-level data interpretation and support CDL-led benefit–risk assessment and clinical positioningGuide development of scientific communications, including publications, congress materials, and clinical summariesMaintain deep understanding of disease biology, evolving treatment paradigms, and competitive landscape to inform clinical interpretation and programme strategyRegulatory and External EngagementContribute senior medical expertise to regulatory interactions and Health Authority discussions, including responses to complex clinical and safety queriesRepresent the programme at advisory boards, steering committees, and external scientific forums, providing senior physician perspective on clinical data and programme directionEngage with KEEs and scientific collaborators to support programme development, scientific exchange, and external credibilityLead or contribute to the clinical and technical diligence assessment of business development opportunitiesCross-Functional Collaboration and Clinical Matrix TeamServe as a senior member of the Clinical Matrix Team (CMT), influencing cross-functional alignment and programme-level decision-makingContribute medical expertise to disease area strategy, integrated evidence planning, and Medical Affairs discussionsCollaborate across functions to ensure alignment on safety, data interpretation, and clinical positioning across the programmeLead or contribute to Oncology Clinical Development-wide initiatives and workstreamsPeople Leadership & Capability DevelopmentProvide oversight, guidance, and mentorship to Medical Directors within the programme, supporting consistency and quality of medical input across studiesSupport development of clinical capability within the medical team, including coaching on medical monitoring, data interpretation, and external engagementContribute to talent development, performance discussions, and capability building within Oncology Clinical DevelopmentBasic Qualifications:Medical degree and completion of advanced specialty training, fellowship or country-equivalent higher-level qualification in oncology or haematology.Experience leading lung cancer drug development, including early phase trials.Clinical and pharmaceutical experience in oncology clinical development, with depth across multiple studies or programmesExperience in medical monitoring, safety evaluation, and clinical data interpretation across clinical studiesUnderstanding of clinical development processes, GCP, ICH guidelines, and global regulatory frameworksExperience operating within cross-functional matrix teams and contributing to complex clinical and programme-level decisionsPreferred Qualifications:Deep expertise in lung cancer, including experience leading or supporting clinical development programs across early and/or late-stage clinical studies.Strong scientific communication and stakeholder engagement skills, with the ability to influence internal and external audiencesDeep experience in oncology clinical development across multiple studies or programmes, including Phase I–IIIExperience contributing to or leading aspects of regulatory interactions (e.g., IND, scientific advice, NDA/MAA)Demonstrated experience engaging with KEEs, advisory boards, and scientific communities in oncologyTrack record of scientific publications and congress presentationsDeep understanding of oncology disease biology and the evolving treatment landscape across solid tumours and/or haematological malignanciesExperience mentoring or providing oversight to other physicians within a clinical development organisationExperience contributing to clinical and technical diligence for business development opportunities#ESMO2026SkillsAnalytical Thinking, Change Management, Clinical Research, Clinical Trial Designs, Communication, Decision Making, Fostering Collaboration, Influencing Without Authority, Leadership, Matrix Leadership, People Management, Risk Management, Strategic Thinking, Strategy Development, Teamwork• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $242,550 to $404,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the Link where you will find answers to multiple questions we receiveImportant notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: UK – London – New Oxford Street; USA • Massachusetts, • Waltham; UK, • Hertfordshire, • Stevenage; Switzerland, • Zug; USA, • Pennsylvania, • Upper ProvidenceType: Full time

Sector: ConstructionReference: BBBH282033_1793893859Commercial Manager80,000 - 100,000LetchworthAre you a Commercial Manager or a Senior Quantity Surveyor looking for a role where you can take real ownership and shape how a growing main contractor operates? Do you want a long-term position with clear progression, including the opportunity to step into a director-level role as the business expands?On offer is a key position within a close-knit, family-run construction contractor, where you will take responsibility for the commercial function and play a central part in the company's next stage of growth. You will have the autonomy to improve processes, support the team, and make a visible impact on project delivery and profitability.The business delivers a mix of new build and refurbishment projects across sectors including commercial fit out, education, healthcare, industrial and heritage works. With ambitious plans to grow turnover over the next two years, they are looking to bring in an experienced commercial lead to support continued success.In this role you will be predominantly office-based in Letchworth, with regular site visits. You will lead and develop a small commercial team, manage contracts and commercial reporting, and support wider operational decision making across projects in London and beyond.This role would suit a Commercial Manager or Senior QS from a main contractor background, looking for long-term progression, genuine responsibility and the chance to help drive a growing business forward.The Role:Leading the commercial function for a growing main contractorManaging and supporting a small team including QS, junior QS and estimatorContract management, commercial reporting and supporting project deliveryThe Person:Commercial Manager / Senior Quantity Surveyor with main contractor experienceStrong contract knowledge (claims experience beneficial)Able to lead, develop people and take ownership within a small, close-knit businessReference Number: BBBH282033To apply for this role or to be considered for further roles, please click "Apply Now" or contact Reece Mitchell at Rise Technical Recruitment.Rise Technical Recruitment Ltd acts an employment agency for permanent roles and an employment business for temporary roles.The salary advertised is the bracket available for this position. The actual salary paid will be dependent on your level of experience, qualifications and skill set. We are an equal opportunities employer and welcome applications from all suitable candidates.Rise Technical Recruitment Ltd acts an employment agency for permanent roles and an employment business for temporary roles.The salary advertised is the bracket available for this position. The actual salary paid will be dependent on your level of experience, qualifications and skill set and will be decided by our client, the employer. Rise are not responsible or liable for any hiring decisions made by the end client.We are an equal opportunities company and welcome applications from all suitable candidates.

This role sits within the Data, Automation and Predictive Sciences (DAPS) division of GSK’s Research & Development (R&D) function and reports into the Senior Director for Cheminformatics. The Data, Automation, and Predictive Sciences (DAPS) function of GSK Research Technologies focuses on large-scale data generation, curation, analysis, and prediction to increase the Probability of Technical and Regulatory Success (PTRS) of assets.Job purpose:The Principal Scientist role (within the Cheminformatics group) uses large proprietary internal datasets to develop, integrate and embed advanced computational methods and predictive in-silico models to accelerate the discovery of medicines. With a focus on machine learning, cheminformatics and computational chemistry methodologies, you will help drive the development and delivery of key new capabilities for our internal automated small molecule design platform coupled directly to lab automation.At GSK we currently have a major R&D initiative focused on transforming small-molecule drug discovery.Responsibilities (include..,):Build, validate and deploy cheminformatics and machine learning methods and models to inform go/no-go across drug-discovery programmes.Integrate with drug discovery programme teams (including DMPK, Toxicology and Safety Pharmacology) to embed predictive models directly into decision-making and translate computational outputs into guidance that is accessible to non-experts.Prototype exploratory, agent-driven workflows that combine LLM-based reasoning with cheminformatics tools, predictive models and experimental data to accelerate hypothesis generation, literature and data triage, and iterative design / make / test / analyse cycles.Contribute to and validate production-quality code implementing state-of-the-art cheminformatics, computational chemistry and quantum chemistry methods that accelerate and improve decision-making on drug discovery programmes.Prepare and present results of key validation experiments, details of capability builds, and developments on drug discovery projects to internal and external groups in a way that is both informative and accessible to the non-subject matter expert.Work with others within a multidisciplinary matrix team that spans different organizations and geographies to execute on joint aims.Please Note If you think you are the right match for the following opportunity, apply after reading the complete description. • Location: This role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge UK, in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.About You:This role is a great opportunity to be instrumental in developing and delivering subject matter expertise across GSK. As this role is multi-faceted and includes collaborating / liaising with a wide variety of stakeholders and matrix teams you must have strong experience of working in complex technical situations, with demonstrable clear problem-solving approach to your work. Strong people skills and a proven ability to influence people to achieve and drive performance are also pre-requisites for this role.About GSK:GSK remains committed to achieving bold commercial ambitions for the future. By 2031, we aim to deliver 40 billion in annual sales, leveraging our existing strong performance momentum to significantly increase our positive impact on the health of billions of patients globally. Our Ahead Together strategy is centered on early intervention to prevent and alter the course of disease, thereby protecting people and supporting healthcare systems. Our diverse portfolio consists of vaccines, specialty medicines, and general medicines. Through continuous innovation and a dedicated focus on scientific and technical excellence, we strive to develop and launch new, groundbreaking treatments that address critical health challenges.APPLICATION CLOSING DATE – Friday 20th of November 2026 (COB).Basic Qualifications:Relevant degree-level education (eg; PhD or MSc in Cheminformatics, Computational Chemistry, Informatics, Life Sciences) or equivalent with a strong Chemistry foundation.Knowledge / Experience of programmatically collecting, combining, mining and analysing complex biological and chemical data to build predictive models.Broad knowledge of computational sciences including machine learning, computational chemistry and cheminformatics methods.Knowledge / Experience of computer programming and scripting languages (eg; Python, Java, C/C++, R).Preferred Qualifications:Knowledge of related disciplines (medicinal chemistry, HT screening, analytical chemistry, systems biology, DMPK, Tox) to enable multidisciplinary approaches to be identified and integrated into a cohesive project plan is preferred.Expertise with chemical toolkits such as ChemAxon, RDkit and scientific pipelining tools such as Pipeline Pilot, KNIMESkillsArtificial Intelligence (AI), Computational Sciences, Computer Programming, Data Analysis, Data Management, Data Modeling, Data Science, Predictive Modeling, Statistical ModelsWhy GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receiveImportant notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: UK • Hertfordshire, • StevenageType: Full time

About GSK Enterprise AI Enterprise AI is GSK’s centre of gravity for applied artificial intelligence. We pair forward deployed engineers and full-stack engineers with scientific, clinical, and business teams to build AI products that get used — not pilots that get archived. We work fast, ship in production, and measure ourselves on outcomes that matter to patients. GSK is a global biopharma company with a purpose to unite science, technology, and talent to get ahead of disease together. We are committed to building a diverse and inclusive team — we welcome candidates from all backgrounds and underrepresented groups in technology, science, and pharma. GSK’s Enterprise AI team translates the promise of AI into measurable impact across drug discovery, development, manufacturing, and commercial. Forward deployed teams embed directly with scientific and business teams to build AI products that change outcomes. This specific role sites in the Chemical Manufacturing & Control (CMC) area. This is the GSK function that turns a validated molecule into a reliably manufactured, quality-assured medicine; its mission is to get safe, effective, consistently manufactured medicines to patients, faster. Its current mission is to double New Product Introductions (NPIs). As a Senior AI Product Manager, you’ll help shape how AI transforms GSK’s manufacturing sites around the world: identifying where it will deliver the greatest value and keeping our teams always focused on the highest-impact opportunities. You’ll partner closely with business stakeholders to prioritize opportunities based on feasibility and value. You’ll take a complex business problem, structure it, size the value, prototype hands‑on, and turn it into something a forward deployed engineer (FDE) can build against. You will run the day‑to‑day tech transfer engagement with sites and Contract Manufacturing Organizations (CMOs), and redesign processes at a detailed level. You will shape the strategy to optimize NPI launches, covering site impact assessment, capacity management, digital twins, scenario planning and virtual commissioning of lines, with the goal of one-click deployment of a new line and product. You will define the target architecture, own the tech transfer package, and drive the AI-native end‑to‑end process redesign. • Surface and size AI opportunities across your assigned engagements and adjacent business units; produce one-page opportunity briefs that are easy to compare and prioritize., • Build credible value cases with finance‑grade reasoning behind cycle time saved, decisions accelerated, revenue uplift, or cost avoided., • Develop hands‑on domain knowledge in your engagement areas — workflows, data, decisions, and the people who own them., • Recommend what to start, continue, and stop across your engagements based on evidence, not enthusiasm., • Sequence work for impact., • Help engineering leads decide what is in scope this sprint, what is next, and what is out., • Define and drive the New Product Introduction (NPI) launch strategy optimization — identify the bottlenecks and levers that shorten time from late-stage development to commercial supply, and quantify the impact on launch timelines., • Lead the architecture definition for AI-enabled tech transfer — the target process, data and agent architecture connecting development, sites, Manufacturing Science and Technology (MSAT) and supply chain, in partnership with FDE pods and enterprise architecture., • Own the definition of the tech transfer package — the content, structure, data and knowledge it must carry — and how it is generated, validated and kept current in an AI native way., • Drive agentification across the end-to-end tech transfer process — decide which steps are automated by agents, which keep humans in the loop, and how agents integrate with site systems (Manufacturing Execution System (MES) and others)., • Lead recipe building for new products — translate process knowledge and the tech transfer package into structured, executable manufacturing recipes (e.g. master and control recipes, ISA-88 style) ready for MES, using agents to draft, check and adapt recipes to each site's equipment and constraints., • Be the day-to-day strategic partner to FDE pods., • Convert business ambiguity into crisp problem statements, success metrics, and decision frameworks engineers can act on., • Run engagement structure end-to-end., • Scope, success criteria, exit conditions, scaling pathways — drafted, agreed, and revisited., • Spot reusable patterns that should become platform capability instead of point solutions., • Operate fluently with Director-level business and scientific stakeholders., • Run working sessions that move things forward and produce decisions, not just notes., • Maintain sponsor confidence with concise updates, honest risk calls, and clear asks., • Track value realization on each engagement against the case you wrote up front., • Capture lessons rigorously and feed them back into how the team scopes the next engagement., • Strong progressive experience in some combination of pharma/life sciences, AI/ML product, product management, or strategy roles in technology-led organisations., • A track record of taking complex, ambiguous business problems and turning them into structured, sized opportunities with defensible business cases., • Working knowledge of GSC and technology transfer processes (sites, MSAT, supply chain), including how decisions actually get made on the ground., • Proven experience engaging sites and operational teams day to day, building trusted relationships and turning their pain points into AI-shaped opportunities., • Comfortable technical fluency in modern AI/ML — enough to design realistic engagements with engineers and avoid hype-driven choices., • Proven experience redesigning business processes at a detailed, step-by-step level in an AI native way, reaching 10x transformation., • Strong individual contributor instincts — you produce quality artefacts, not status updates., • Foundations in product management discovery and value framing., • Experience working with site MSAT, technology transfer leads, or manufacturing operations teams., • Experience with Manufacturing Execution Systems (MES) and adjacent site systems (e.g. Laboratory Information Management System (LIMS), Enterprise Resource Planning (ERP), Quality Management System (QMS), historians, electronic batch records), and an understanding of how their data feeds tech transfer and launch readiness., • Experience building and authoring manufacturing recipes in MES and automation platforms (e.g. PAS-X, Syncade, DeltaV), and in managing recipe changes across sites., • Familiarity with DTLS and similar technologies — digital twin, process modeling and simulation tools — and how they inform recipe design, scale-up and tech transfer decisions., • Experience working with data analytics, data science, or process science teams to bring a 10x change in modeling, optimization, and simulation., • Experience in regulated industries (pharma, healthcare, financial services) and familiarity with good practice regulations (GxP) and data-governance constraints., • Prior experience as an AI product manager at an AI-native company (Anthropic, Palantir, OpenAI, or similar) or at a hyperscaler., • Bachelor’s degree in Computer Science, Software Engineering, or equivalent practical experience., • Master’s degree in Computer Science or related field is advantageous. This is a UK based hybrid role, with a min of 2/3 days a week onsite. Fully remote working is not available. Locations: 1) HQ Central London or 2) Stevenage - This role can be temporarily be based at Stevenage location. However, the Company plans to relocate its offices to Ware, UK. The location of this role will therefore subsequently change to Ware, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029. You are practical, inclusive and open to feedback. You bring technical understanding and strong empathy for users. You work in active voice and keep communication simple. You support colleagues and help teams make confident, evidence-based decisions. You want to grow your product and security skills while delivering outcomes that matter. You will join a supportive team that values clear communication and practical problem solving. You will have access to learning and development to grow both technical and leadership skills. Your work will support technology that enables critical work across the company and helps improve healthcare outcomes. • AI Platforms, • Change Management, • Data Analysis, • Feature Prioritization, • Machine Learning Model Management, • ML Platforms, • Model Evaluation, • Performance Analysis, • Product Delivery, • Product Design, • Product Lifecycle Management (PLM), • Product Roadmapping, • Roadmap Development, • Statistical Analysis, • User Needs Analysis Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at . We are a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years. Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Find out more on our career site. Closing Date: 13th November 2026 #J-18808-Ljbffr

We are currently looking to recruit a Construction Manager to work in our Offices based in Bournemouth or Welwyn Garden City on a full-time basis. • To ensure that Safe System of Work Packs (SWP) have been prepared for activities as required by our Safe Work Planner, • Liaising with the client regarding technical queries prior to start of works on site, • Liaising with the Resourcing Staff regarding resource availability, • Liaising with the Head of Estimating to develop scopes and quotations for submission to clients – ditto for V.O. changes on existing projects, • Develop work package scopes as required by the client, • Verifying that the specified levels of protection are appropriate to location and nature of work, • Deal with issues arising from each project, • Generate project & possessions programme. Assess plant and material requirements, • Liaising with purchasing department to ensure all project supply chain requirements are delivered on time, • Ensure that all CPPs, WPPs, Section 61, Traffic Management orders, Ecology Surveys Risk Assessments and Safe Systems of Work as appropriate are in place prior to start on site, • Attend pre start meetings with client, • Keep accurate records of all work carried out, • Ensure client receives communications on progress and problems include General Manager in on communications, • Manage day to day issues as the project progresses, • Monitor progress of the works, keeping to programme, • Inspect quality of work and signed off at stages, • Record information for hand over documentation, • Double check arrangements by others that you are reliant on, • Inspect works and snag with client, • Sign off each job as completeComplete hand over documentation, • Report on operatives/subcontractors’ performance, workmanship and quality of finished job on each completed job, • Shift reports, • CCTV Survey Reports (where appropriate), • Develop improvement plans for future works based on “lessons learned”, • Deliver projects to the agreed budget, • Do not start works without a client PO, • Ensure VOWD is applied for each period, • Liaison with NR customers, • Liaison with the Operations Director, • Liaison with HSQE Director on specific issues outside of competency, • Liaison with the Training Manager, • Liaison with the Commercial Director, • NR Life Saving Rules Compliance, • Engineering / Construction – Degree or HND, • Current full driving license, • Safety Awareness, • CSCS Card, • 3 years post qualification experience in construction industry, • 7 years’ experience in the Railway Industry, • CPP, Works Package Plan and Risk Assessment Preparation, • MS project / knowledge of Prima Vera P6, • CDM, • Temporary Works, • NR Standards, • Quality completed works, • Control of labour/man management, • Accuracy of shift reports, • Works completed to time and budget, • Motivation, • Safe systems of work. As a Pro Rail team member we will provide the successful applicant with: • Free on-site parking, • Office hours 9am – 5pm, • A clear opportunity to develop and grow your career through training and further qualifications, • An environment where your health and personal well-being comes first and to be part of a close working, fast paced team, • A laptop, • To be enthusiastic, • To work well within a diverse team, • To be honest Pro Rail Services is a national railway civil engineering contractor delivering specialist innovative and effective solutions to the UK rail infrastructure industry. We are a family run business leading the way in innovation for railway engineering, infrastructure and plant. Our commitment to self-delivery ensures the highest levels of safety and delivery performance. Our management team has over 25 years’ experience in delivering complex multi-million-pound programmes, providing dynamic solutions to complex organisational, technical and commercial problems. We are a Network Rail POS licence holder with our own fleet of specialised road rail vehicles and drainage plant and attachments, we retain our own skilled labour and safety critical staff, and can provide a full survey, design and build solution. We are also a Network Rail Principal Contractor and hold our own PCL licence. We are a Zero RIDDOR business since our inception in 2012 and have never handed back a possession late. It is the policy of Pro Rail Services to provide equal employment opportunities to all persons. We do not discriminate on the basis of race, religion, creed, gender, sex, age, disability, national origin, ancestry, sexual orientation, gender identity and/or information or any other characteristic protected by law. We will take additional measures to support anyone who may need assistance throughout our recruitment process. We are not an immigration sponsored company and so are unable to accept applications from anyone who does not hold the correct documentation allowing them to legally work in the UK. #J-18808-Ljbffr

Clearline Recruitment Ltd is assisting a global pharmaceutical client to appoint an Associate Director of Pharmacovigilance in Welwyn Garden City. This senior role provides scientific leadership across pharmacovigilance and safety science, supporting clinical development and post-marketing products within a global safety framework. The role offers hybrid working (2 days in the office), a 12-month contract outside IR35, and exposure to strategic safety initiatives within a collaborative global #J-18808-Ljbffr

Technical Manager (NPD / Electronics) £70,000 - £80,000 + Progression + Yearly Bonus + 27 Days Holiday + Bank Holiday + On - Site Parking Hertfordshire Are you an Technical Manager from the electronics industry who is looking for an exciting opportunity within a specialist company that will allow you to make the department your own whilst also providing fantastic benefits? The company are a leading specialist in lighting control systems; they provide solutions for most industries some of their most notable projects have been Porsche Mayfair, the O2 Arena London and the F1 Arcade in London. Since launching the company, has created sustainable growth by always breaching into new markets and never allowing themselves to settle, striving for new business and prioritising employee satisfaction. The successful candidate will be responsible for overseeing the entire research and development process, you will be reporting directly to the Managing Director. This role would suit an Technical Manager from an electronics background who is looking to join a growing company that can offer fantastic benefits whilst also providing the opportunity to make a team your own. The Role : Define and execute the R&D strategy aligned with business objectives, technology roadmaps, and market requirements. Identify and manage sub-contractors as required. Maintain technical authority across all R&D activities, ensuring robust engineering practices, documentation, and design reviews. Work closely with the Sales and Engineering Departments to translate market needs into clear technical product specifications. The Person: NPD or R&D experience within the Electronics Sector Previous senior management experience If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV. Keywords: R&D Manager, Management, Electrical, Leadership, Hertford, Industrial, Analogue, Lighting, Lighting Controls, Manufacturing, Electronics, On-Site Parking, Bank Holiday, Monday-Friday, London. Job Reference: BBBH27483c We are an equal opportunities employer and welcome applications from all suitable candidates. The salary advertised is a guideline for this position. The remuneration offered will be dependent on the extent of your experience, qualifications, and skillset. Ernest Gordon Recruitment Limited acts as an employment agency for permanent recruitment and employment business for the supply of temporary workers. By applying for this job, you accept the T&C's, Privacy Policy and Disclaimers which can be found on our website. TPBN1_UKTJ

Commercial Property Lawyer / Legal Director - Ready for your next move in commercial property Find out exactly what skills, experience, and qualifications you will need to succeed in this role before applying below. Spider is advertising on behalf of Ellisons , who are looking for talented commercial property professionals to join their established team. Whether you're a Commercial Property Lawyer with 2-4 years' PQE or an experienced lawyer ready for a Legal Director position, there's an opportunity to make your mark. This is a full-time, permanent role , based in either their Ipswich, Colchester, Bury St Edmunds or Chelmsford office. Fantastic company benefits include: Salary: Competitive + discretionary performance bonus Benefits: Generous leave entitlement, enhanced family policies, mental health and wellbeing support, and professional development About the role Interesting work, genuine responsibility and room to grow. You'll advise a diverse client base, including investors, developers, landlords, tenants and businesses, on a broad range of commercial property matters. Your work could include: Managing freehold and leasehold acquisitions and disposals Drafting and negotiating commercial leases and advising on landlord and tenant matters Handling property development, investment and finance transactions Building strong client relationships and delivering practical, commercially focused advice Identifying business development opportunities and supporting departmental growth Collaborating with colleagues across the firm For more senior candidates , the role will also offer opportunities to lead complex transactions, develop your own practice, mentor colleagues and influence the department's strategic direction. About you You'll be a qualified solicitor or suitably qualified lawyer with strong commercial property experience, excellent communication skills and sound commercial judgement. If you have 2-4 years' PQE , you'll be confident managing your own caseload with appropriate support and keen to develop your expertise. If you're an established senior lawyer , you'll bring substantial experience, strong client relationships and the ambition to drive business development and help shape the team. Whatever your level, you'll be proactive, collaborative and committed to delivering excellent client service. About Ellisons Ellisons is an established regional law firm with a strong commercial property practice across East Anglia. You'll join a supportive team offering the opportunity to develop your career, build lasting client relationships and contribute to the firm's continued success. Ready to see where your career could go Apply through Spider with your up-to-date CV. Spider is committed to equal opportunities and welcomes applications from suitably qualified candidates. Please advise us of any reasonable adjustments required during recruitment. Please check your inbox and spam/junk folder for correspondence. Additional keywords: Commercial Property Lawyer, Legal Director, Commercial Property Solicitor, Real Estate Solicitor, Property Lawyer, Commercial Leases, Property Development, Property Finance, Business Development, Ipswich, Colchester, Bury St Edmunds, Chelmsford. This vacancy is advertised and managed on our behalf by Spider. Your details will be processed for this vacancy, and you may be contacted by email, text or telephone. xrnqpay Full Privacy Policy details will be provided by email upon application.

Director, Cardiovascular and metabolic diseases, Clinical Pharmacology Modeling and SimulationFor candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. Do you have the right skills and experience for this role Read on to find out, and make your application. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.The Department of Clinical Pharmacology Modelling & Simulation in Respiratory and Inflammation (CPMS R&I) at GSK is recruiting for a Director–level Clinical Pharmacologist with cardiovascular and metabolic disease expertise.This role sits within the newly established Clinical Pharmacology and Quantitative Medicine (CPQM) organisation, which aims to be a centre of excellence in Model‑Informed Drug Development (MIDD) by integrating clinical pharmacology, digital medicine, translational imaging and mechanistic/systems modelling.You will lead the end‑to‑end application of MIDD across the drug development lifecycle • from first‑in‑human studies through filing and lifecycle management, • and provide clinical pharmacology strategy and evidence‑generation input. This is an opportunity to join a highly regarded, high‑impact team with a strong publication track record, reporting directly to the Respiratory, Immunology & Inflammation Research Unit (RIIRU).Main responsibilities and accountabilities include, but are not limited to:• Design & Execute Model Informed and Clinical Pharmacology strategiesDevelop and implement robust MIDD & ClinPharm evidence strategies to de risk and accelerate RIIRU programs. Aim for faster development, optimal dosing and stronger regulatory positioning across respiratory, inflammation, neurodegeneration and emerging areas — and support business development opportunities.• Ensure robust ways of working and regulatory ready evidenceDraft and review clinical pharmacology regulatory content to support timely approvals and optimal labelling. Maintain up to date knowledge of FDA, EMA, CDE, PMDA and ICH expectations and embed regulatory considerations and best practices into study design and MIDD strategies.• Build cross functional partnershipsWork closely with CPQM peers (digital medicine, translational imaging, MIDD specialists, mechanistic/systems modelling) and cross functional partners (biology, data science, computational biology, clinical, etc.). Maintain strong networks and share best practices in the CPMS community of practice. Build strong network key functions such as AI/ML, biomarkers, biostatistics, clinical operations, data science, computational biology and RWE to embed quantitative approaches into decision making at asset level.• External engagement & scientific leadershipRaise GSK’s profile in MIDD, clinical pharmacology, QSP and AI/ML integration through publications, conference presentations and active participation in scientific and regulatory fora to influence method adoption and regulatory dialogueWhy you?Basic Qualifications:We are looking for a professional with these required skills to achieve our goals:• PhD, MD, or PharmD• 5+ years of industry experience in clinical pharmacology, modelling/simulation and drug development to solve practical problems in pharmaceutical industry.• Experience in pharmacometrics and its application to clinical questions in drug development.Preferred Qualifications:• Experience in Cardiovascular and metabolic diseases.• Demonstrated experience of collaboration in a multi-disciplinary team, using effective communication and taking personal accountability for timely delivery of results.• Evidenced experience making sound judgement in complex situations and adapting to changing business needs by prioritizing multiple tasks.• Experience working with senior stakeholders in a cross functional environment.• Track record of implementation of Model-Informed Drug Discovery and Development (MIDD) approaches to accelerate patient access to novel therapies and to expand therapeutic indications of marketed drugs.• Drive and learning agility to build knowledge on a drug-disease system, symptom progression, standard of care, and trial design.SkillsDrug Design, Drug Development, Drug Discovery Process, Drug Discovery Research, Medication Safety, Molecular Modeling, Pharmaceutical Regulatory Compliance, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacology, Pharmacometrics, Pharmacovigilance, Study Design, Target Validation• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $188,100 to $313,500. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: USA • Massachusetts, • Waltham; GSK HQ; UK, • Hertfordshire, • Stevenage; Baar Onyx; USA, • North Carolina, • Durham; USA, • Pennsylvania, • Upper ProvidenceType: Full time

At GSK we are looking for a highly capable senior technical builder who can design and govern the data-flows that GSK’s Research & Development (R&D) division runs on. If you believe data should move on its own and still arrive trusted, then this role could be for you. The Data Flow Lead role reports directly into the Senior Director for Data Governance, Innovation & Automated Compliance, and sits within the Data Value Office (DVO) for the Chief Medical Officer (CMO) organization of GSK’s Research & Development (R&D) function. This role is focused on delivering data-flows-as-product, compliance-as-code, and governance built into the pipeline (instead of bolted-on). You will turn scattered systems and sources into modular, reusable, end-to-end flows in one consistent format that can be used to its full potential throughout GSK’s R&D divisions. Your mission is to make R&D data visible, trusted and automation-ready (by default) so teams can decide faster and scale agentic solutions with confidence (whilst keeping the human expert in the loop). • Manage the development of business requirements for data-flow (through collaboration with R&D business/functional leads and data platform colleagues) to translate business needs into technical data requirements and processes to ensure seamless data-flow integration and usage across the R&D ecosystem., • Design, develop and maintain modular, end-to-end data-flows (spanning roles, interfaces, data and metadata, triggers and access) to integrate systems and data sources into trusted, reusable assets across R&D (including writing clean, readable code where required)., • Ensure data-flows support compliance-by-design; integrating, contextualising and orchestrating data and systems in line with compliance principles., • Deliver pre-packaged, curated data-flows aligned to business requirements, which include documented data specifications describing processing steps required to generate each flow., • Integrate diverse data-flows (eg; protocol development, Development Safety Update Report (DSUR) and clinical trial Individual Human Data (IHD)) into a unified machine readable format for consistent implementation and an end-to-end data ecosystem., • Ensure deliverables are appropriately quality controlled, documented and, where required, able to be handed over to function leads and the R&D Tech team for scale implementation. This extends to quantifying and providing insights into business impact and value creation arising from data-flow activities., • Coaching and peer review to ensure the team's work reflects industry best practice for data-flow creation activities, including data standards. GSK HQ London, Stevenage, or Ware R&D. If the successful applicant is based at Stevenage site: This role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge UK, in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029. Please note that this role is not a documentation role. We are looking for a capable technical subject matter expert with experience of delivering sophisticated date‑flow solutions. You will be confident with metadata ecosystems and agentic workforces (and related agentic decision‑making processes). We are currently operating with Azure (but applicants with experience of similar systems are encouraged to apply, including GCP). As this role is multi‑faced and includes collaborating / liaising with a wide variety of stakeholders and matrix teams you must have strong experience of working in complex matrix‑environment, with demonstrable clear problem‑solving approach to your work. At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together. Find out more - our approach to R&D: en-gb/innovation/ • Relevant degree‑level education (eg; BS/MSc/PhD (or equivalent) in Computer Science, Mathematics, Statistics or a related subject)., • Relevant experience / knowledge of translating business needs into technical data requirements and processes, ability to quantify and provide insights into business impact and value creation from data‑flow activities, and handling complex data‑flow processes efficiently., • Knowledge / experience of metadata ecosystems and agentic solutions., • Relevant hands‑on experience with policy engines, including translating governance requirements into practical, executable Policy as Code., • Relevant experience in integrating multiple data sources and systems into unified reusable data‑flows ( whilst ensuring data privacy and compliance‑by‑design)., • Proficiency with a range of digital tools (eg; Auzure, GCP) and experience leveraging AI or digital technologies to improve efficiency or insights. Artificial Intelligence (AI), Computational Sciences, Computer Programming, Data Analysis, Data Management, Data Modeling, Data Science, Predictive Modeling, Statistical Models Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state and local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at #J-18808-Ljbffr

Love the Numbers. Understand the Business. Help Shape What Comes Next. Welcome to Tewinbury Group, an entrepreneurial, family-run hospitality business growing at around 15% year on year. Rooted in farming, our Hertfordshire portfolio includes Tewinbury Farm Hotel, The View at Panshanger Golf Course, Hertford House Hotel and a 700-acre working farm, alongside events, wellness experiences and exciting new projects. We're looking for an experienced Head of Finance & Commercial to lead our finance function and become a trusted commercial partner to the family and leadership team. This is a broad, hands-on role in a close-knit, no-egos business where everyone mucks in. You'll ensure the numbers, controls, cash and compliance are right, while helping operational leaders improve performance and turning commercial opportunities into practical, measurable results. Rigorous about the fundamentals. Entrepreneurial in outlook. Commercially switched on. Head of Finance & Commercial Tewinbury Farm Hotel | Welwyn, Hertfordshire Site-Based | 5 Days per Week | Some Flexibility Salary DOE + c.15% Profit-Based Bonus Full-Time | Permanent | 40 Hours Reporting to: Director of Strategy Direct Reports: 2 Start Date: ASAP Preferred You'll lead finance across multiple Group entities, taking responsibility for the day-to-day financial operation, reporting, controls and compliance. • Period-end close across 13 four-weekly accounting periods, typically completed within a week, including reconciliations and management accounts, • Budgets, rolling forecasts, board reporting and financial analysis, • Multi-entity accounting, intercompany recharges, departmental cost centres and consolidated reporting, • VAT across mixed income streams, including accommodation, F&B, events, memberships, property and farming, • Supplier payments, banking, cash flow, working capital and debt facilities, • Multi-site payroll, pensions, PAYE, tips and service charge administration, • Maintaining robust financial controls, compliance and effective processes, • Overseeing year-end, statutory accounts and corporation tax alongside external accountants, • Leading and developing a small, established finance team We don't want someone who simply produces a report and hands it over. We want someone who spots the opportunity, builds the plan and helps make it happen. You'll work with everyone from restaurant managers and kitchen teams to the family board, helping non-finance colleagues understand their P&Ls, identify variances and improve performance. That means getting underneath labour costs, rotas, stock, gross profit, event profitability and operational efficiencies, then working with the teams to deliver improvements across the Group. You'll be the person who can quickly build a practical financial model, assess the potential return, highlight the risks and help determine whether it's worth pursuing. • Procurement, supplier negotiations and cost-saving initiatives, • Commercial agreements, insurance renewals and risk management, • Rental income, leases and partner arrangements, • Capital expenditure and building project costing, • Financial modelling for new opportunities, venues and business initiatives, • Supporting operational leaders to implement commercially sound decisions Technology and automation are important priorities for Tewinbury, with strong support from the board. You’ll oversee the Group's finance and operational systems, including Xero, Moss, Mews, Lightspeed, Event Temple and Microsoft 365, ensuring data flows accurately between platforms and identifying opportunities to improve integration. We’re particularly interested in someone who sees the potential of AI, automation and better reporting to reduce manual work, simplify processes and give managers faster access to useful financial information. The aim is to build a leaner, more effective finance function that spends less time assembling reports and more time helping the business perform. Strong hospitality finance experience is a priority. You’ll have proven finance leadership experience within hotels, multi-site restaurants or a comparable hospitality or leisure environment, ideally supporting a business with £10m–£20m turnover through growth. • Hands-on financial management across period-end, management accounts, budgets and forecasts, • Strong VAT knowledge, ideally involving multiple entities and varied income streams, • Experience managing cash flow, banking, payments, payroll and financial controls, • Commercial business partnering within an operational hospitality environment, • Confidence analysing profitability, identifying opportunities and implementing improvements, • The ability to produce practical financial models and business cases at pace, • Experience leading a finance team and working with external accountants, • Strong systems capability and an interest in AI, automation and process improvement, • Excellent stakeholder management, with the confidence to challenge senior leaders constructively, • The ability to manage competing priorities, work independently and adapt to a fast-moving business A professional accounting qualification is desirable, with CIMA preferred, although ACA, ACCA, part-qualified and strong qualified-by-experience candidates will also be considered. Relevant hospitality experience and proven delivery matter more to us than qualifications alone. Experience with hospitality PMS/POS systems, commercial insurance, banking facilities, capital projects, contracts or finance systems implementation would also be valuable. Nobody is above helping out. No egos. Just people who care about making the business work. You’ll ideally live within a 30–40 minute commute of Tewinbury. Welwyn North station offers connections from North London, although onward transport is needed to reach the hotel. You’ll have a genuine seat at the leadership table of a growing family business, with the autonomy to improve how finance operates and the opportunity to influence commercial decisions across a diverse hospitality portfolio. • Competitive salary DOE, • Profit-based bonus of circa 15% of salary, • Subsidised Farm Fitness gym membership, • Hotel stays at Tewinbury and partner hotels as part of R&D, • Employee discounts across Tewinbury Group venues If you're a hands-on hospitality finance leader who enjoys being close to the operation, bringing commercial ideas to life and making a tangible difference, we'd love to hear from you. Application notice... We take your privacy seriously. As you might expect you may be contacted by email, text or telephone. Your data is processed by our talent partner RR (Recruitment Revolution) on the basis of their legitimate interests in fulfilling the recruitment process. Please refer to their Data Privacy Policy & Notice on their website for further details. #J-18808-Ljbffr

Job Description Below covers everything you need to know about what this opportunity entails, as well as what is expected from applicants. Join Our Award-Winning Team as a Registered Manager! Salary: From £43,000 per year + Bonus| Full-time, Permanent Location: CareYourWay Stevenage About Us: CareYourWay is a well-established and award-winning provider known for excellence in care and our commitment to supporting our staff. As part of the CareYourWay family, you will have the opportunity to play a pivotal role in shaping the growth and quality of our services, championing outstanding standards for people being cared for in their own homes. As part of CareYourWay's exciting expansion, we're launching a brand-new CareYourWay territory in Stevenage, Letchworth and Hitchin, and are looking for a Registered Manager to join us at this early stage. The Role: As a Registered Manager, you will be at the heart of our service, driving exceptional care delivery and inspiring a culture of inclusivity and excellence. This is a launch opportunity: you'll be joining at the start of a new territory, helping to build the team and client base alongside the Director. This role is perfect for someone who is passionate about person-centred care, motivated by high standards, and ready to lead a dedicated team. Key Responsibilities: • Lead and inspire the care and administration team, ensuring exceptional service delivery., • Develop strategic plans and oversee the implementation of policies and procedures., • Maintain effective working relationships with colleagues and stakeholders., • Drive quality control through regular audits, client visits, and evaluations., • Ensure all care planning and risk assessments are compliant and support clients in achieving their individual outcomes., • Support the business growth by converting new enquiries into efficient care services., • Actively manage incidents and complaints, driving continuous improvement., • Lead recruitment, staff inductions, appraisals, and professional development., • Coordinate with Directors to expand high-quality home care in the local area., • Participate in the on-call function, including weekends and bank holidays. About You: We are looking for someone who is: • Passionate about quality care: A deep commitment to delivering outstanding, person-centred care., • Experienced: Previous experience as a Registered Manager or Deputy Manager in domiciliary care or ready to step up., • Commercially aware: Effective resource management., • A strong leader: Able to motivate, manage, and develop staff., • Organised and proactive: Able to plan, prioritize, and work well under pressure., • Communicative: Excellent verbal and written communication skills., • Compliance-focused: Familiar with CQC regulations and quality assurance., • · Adaptable and solution-oriented: Agile in addressing challenges with a calm approach. Requirements: • CQC registration qualifications., • Extensive care experience with a proven track record., • Comfortable operating with the autonomy and hands-on pace required in the early stages of a new service, working closely alongside the Director., • Strong IT skills and familiarity with care management systems., • Full driving license and access to a reliable vehicle. What We Offer: • Competitive salary from £43,000 per year., • A chance to be part of an award-winning team committed to quality care., • The opportunity to be part of a new territory from its early stages, helping to build a strong local team and reputation as part of an established national franchise., • Ongoing professional development and training opportunities. xrnqpay, • A supportive and inclusive management culture that values your contributions. If you are ready to lead with compassion, inspire a team, and drive excellence in home care, we want to hear from you! Apply today and be part of a team that makes a real difference every day.

This is a unique opportunity to play a leading role in how software products are built within a leading global retailer with real impact across millions of customers and thousands of software engineers. Reporting to the Director of Engineering Effectiveness and Capability, you will lead teams that focus on overall developer experience, developer tooling and will lead our efforts to evolve how software engineering is done in the world of agentic AI. You’ll play a key role in shaping strategy as well as driving execution. You’ll provide thought leadership through keeping your knowledge and expertise in agentic coding up to date through continual evaluation of new technologies and practices and be able to balance pace of delivery with the need to be secure, resilient and prudent. The impact of your work will be felt by over 2,500 software engineers. You’ll manage and provide leadership to teams based in India and Hungary. • Budget ownership, partnership and commercial relationships with existing suppliers in the developer tooling and agentic coding space. Continual evaluation of new tools and build vs buy decisions., • The ongoing evolution and operational excellence of our key developer tools such as GitHub, SonarQube Nexus and others that support software development activities., • Key input into the definition and continual evolution of the strategy for how our SDLC evolves in the light of Agentic AI., • Accountability and leadership to execute how agentic AI is enabled for development teams., • Thought leadership across the whole Technology organisation around Agentic AI for coding and other aspects of the SDLC., • Overall ownership of developer experience including gathering quantitative and qualitative data, driving insight and identifying areas of opportunity., • Proven experience of leading geographically disparate teams and managing managers., • Ability to shape strategic direction; deal with ambiguity and operate autonomously in a fast-evolving space making timely decisions without perfect data and be able to operate in an intent-based way vs seeking approval., • Strong ability to make decisions that balance multiple, often conflicting factors., • Excellent communication and influencing skills downwards, across and upwards., • Proven experience in managing significant vendor relationships, evaluating offerings and working effectively with procurement and legal teams., • Strong understanding of budgets, forecasts and the economics of software development activity and agentic AI., • Experience of working in an organisation that values product-led and data-led problem definition and discovery., • A solid understanding of all aspects of a typical SDLC and opinions on where AI can have the biggest impact., • Prior experience as a hands-on software engineer which allows you to have a strong understanding and empathy of engineers’ needs and views., • Experience in leading teams who ‘run what they build’, managing effective operational support and on-call engineers., • Ideally: prior experience of working in a developer experience, platform engineering or similar role., • You are naturally curious and have built up expertise with agentic coding tools such as Claude Code, Codex, OpenCode or Cursor but you have a bias towards solving problems not dogmatic solutions., • Ability to keep knowledge up to date through effective building of networks, data sources and ability to identify and distil key trends and directions and then apply context to how you interpret them., • Strong system design and architecture skills and instincts., • Exceptional people management skills including how to manage talent and performance and grow the people around you. You might know us as a supermarket, technology company or even for our award-winning mobile network. Truth is, we’re all of those things, and much more. Our colleagues work with one goal in mind, helping to make every day a little better for our customers, colleagues and communities all over the world. No two customers are the same, neither are our colleagues. At Tesco, we champion a balance that lets you thrive both in and out of work. Spend 60% of your week collaborating with colleagues at our office locations or local sites and the rest remotely. Whether you're just kicking off your career, juggling passions, or navigating big life events, we're here to support you. We always welcome a conversation about flexible working, so talk to us throughout your application about how we can support. We're proud to be an accredited Disability Confident Leader, where everyone’s welcome. That’s why we commit to providing a fully inclusive and accessible recruitment process. #J-18808-Ljbffr

VolkerWessels UK is a market leading contracting group of five closely linked businesses. We provide integrated and ground-breaking solutions for the civil engineering and construction sectors, with specialisms in rail, highways, airports, marine, defence, energy, water, and environmental infrastructure. VolkerWessels UK is looking for a Head of Business Systems to take ownership of the applications that underpin our business operations, ensuring they are reliable, integrated, and aligned with our strategic goals. Reporting to the ICT Director, you'll lead our Application Development, Testing, Application Support and Application Support Specialist teams, driving innovation, continuous improvement, and operational excellence across our business systems landscape. A key part of this role will be acting as the recognised business authority for Microsoft Dynamics 365 Business Central (4PS), partnering with senior stakeholders across Finance and the wider business to maximise system capability and support future growth. About our role What you'll be doing: Leading the strategy, roadmap, governance and lifecycle management of our business applications portfolio. Acting as the business expert for Microsoft Dynamics 365 Business Central (4PS). Managing and developing high-performing teams across application development, testing and support. Overseeing application development and solutions built on Microsoft Power Platform. Driving system integrations, ensuring secure, resilient and scalable data flows. Supporting business transformation through technology and process improvement. Managing key supplier relationships, including Microsoft and 4PS. Working closely with senior leadership to align technology solutions with business objectives. Ensuring robust controls, compliance and governance across critical business systems. About you We're looking for a strategic technology leader who combines strong technical expertise with excellent business and stakeholder management skills. You'll bring: Significant experience leading business systems, application development and support functions. Strong expertise in ERP platforms, Microsoft Dynamics 365 Business Central is essential and 4PS advantageous. Experience managing technical teams within complex business environments. Knowledge of Microsoft Power Platform, integrations, APIs and application architecture. A strong understanding of finance, commercial and operational processes. A proven ability to influence and partner with Executive and senior leadership teams, translating complex business challenges into data-driven technology solutions that deliver strategic value, operational improvement, and competitive advantage. Experience within construction, engineering, infrastructure or project-led organisations would be highly advantageous. If your past experience doesn't match perfectly with every requirement of the job description, we still encourage you to apply. You may be just the right candidate for us. Why work with us? VolkerWessels UK operate through five separate, but complementary businesses, working in collaboration and using our specialist skills to deliver an integrated service for our clients. At any one time, our people are working on our sites or in our offices, for around 250 projects across the UK. Everyday we overcome challenges, fulfilling our commitments, no matter what. That's what our business is about, that's how our people find satisfaction in their jobs. We offer competitive rewards and benefits, recognising the value we place on our employees. We offer a range of benefits, including: Competitive salary Competitive annual leave and an additional day off on your birthday Option to buy additional annual leave Private medical care Pension Life Assurance Cycle to Work scheme Shopping and restaurants vouchers, rewards, and discounts Training and development opportunities-comprehensive skills-based training Family friendly polices including enhanced maternity benefits Flexible working opportunities Employee Assistance programme Mental health, physical health, and financial support 24/7 Virtual GP service Fairness, inclusion and respect We believe in pushing boundaries in the pursuit of fairness, inclusion and respect. So, our teams can be comfortable that, whatever their background, VolkerWessels UK is a place where they can be themselves and thrive. If you need support with your application, please contact us at Additional information Note for Recruitment Agencies: Our preference is to hire directly, and we will reach out to our Preferred Supplier List (PSL) agencies if this particular role qualifies for release. We kindly request that you refrain from sending speculative CVs. In the event of speculative CV submissions, no fees will be applicable, and we kindly ask that all inquiries to be directed VolkerWessels UK is committed to maintaining healthy, safe and productive working conditions for its entire staff and therefore a drugs & alcohol screening is mandatory for all. #LI-KP2 TPBN1_UKTJ

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