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Ophthalmology Bioassay Senior Scientist Nottingham | On-site We are seeking an Ophthalmology Bioassay Senior Scientist to join a growing, innovative CRO environment focused on developing next-generation human-relevant disease models. This role sits at the forefront of moving drug discovery away from traditional animal models, with a strong emphasis on advanced in vitro systems, including iPSC-derived models and 3D organoids for ocular diseases. You will play a key role in building and developing capability in ophthalmology, contributing to both project delivery and the longer-term growth of this area of the business. This is an excellent opportunity for someone who enjoys combining hands-on lab work, scientific innovation, and commercial impact. Responsibilities: Ocular Model Development • Develop and optimise human-relevant ocular disease models, • Design and implement iPSC-derived systems, including retinal and epithelial models, • Contribute to the development of complex 3D organoid and co-culture systems Assay Development & Delivery • Design and execute bioassays relevant to ocular disease, including:, • Imaging and fluorescence-based assays, • Immunoassays, • Functional and translational assays, • Analyse and interpret experimental data and present findings clearly to stakeholders Molecular & Cell Biology • Apply molecular biology techniques including:, • Gene knockdown approaches (e.g. siRNA, shRNA), • Work with primary cells, cell lines, and stem-cell derived models, • Support development of increasingly complex and physiologically relevant systems Project Delivery & Growth • Support delivery of CRO projects across drug discovery programmes, • Troubleshoot experimental challenges and drive continuous improvement, • Contribute to building and scaling ophthalmology capability, including future team growth, • Engage with clients and support scientific discussions where required About You You are a scientist with strong hands-on experience in advanced cellular models, particularly within ophthalmology or closely related disease areas. You’ll bring: • Experience working with iPSC-derived systems and/or 3D organoid models (critical), • Strong laboratory experience across bioassays, imaging, and molecular biology techniques, • Experience working with ocular models or strong transferable cell biology experience, • A proactive, problem-solving mindset with the ability to work independently Desirable (but not essential): • PhD in Ophthalmology, Cell Biology, Stem Cell Biology, or a related discipline, • Experience in a CRO or fast-paced applied research environment, • Exposure to replacing or reducing animal models with human-relevant systems, • Interest in helping build or grow a new scientific capability or team If you’re excited by organoids, stem cell models, and reducing reliance on animal testing, this role will give you the platform to make a real impact. Apply now by attaching your CV in Word, or contact Paige Keenan for further information about this new role: paige.keenan@srgtalent.com

Skin Bioassay Senior Scientist Nottingham | On-site We are seeking a Skin Bioassay Senior Scientist to join a growing CRO environment developing advanced in vitro skin models and bioassays for both pharmaceutical and cosmetic applications. This role is part of a strategic expansion of in-house skin capabilities, supporting both ongoing projects and the development of new model systems. You will play a key role in generating high-quality datasets, developing human-relevant skin models, and delivering impactful assay results for clients. Working within a collaborative, fast-paced laboratory environment, you will contribute to the development of next-generation skin models, including reconstructed and full-thickness systems, while supporting a broad range of client-driven and internal projects. Responsibilities: Skin Model Development • Develop and optimise in vitro skin models, including:, • Reconstructed Human Epidermis (RHE) models, • Full-thickness or full-skin equivalent systems, • Contribute to the evolution of increasingly complex, physiologically relevant models Assay Development & Delivery • Design and execute cosmetic and skin-related bioassays, including:, • Cell proliferation and viability assays, • Cytokine release and inflammatory markers, • Barrier function and sensitivity assessments, • Analyse and interpret experimental data, ensuring generation of robust, client-ready datasets Molecular & Analytical Techniques • Apply a range of techniques including:, • ELISA and immunoassays, • qPCR and molecular biology workflows, • Plate-based assay readouts, • Use imaging and histology-based approaches to assess skin structure and function Applied Skin Science & Testing • Evaluate cosmetic formulations and active compounds, • Investigate:, • Ageing processes and protective effects, • UV response (using in-house UV systems), • Key skin proteins such as keratin and structural markers Project Delivery & Lab Operations • Deliver experimental work in line with project timelines and client expectations, • Prepare SOPs, reports, and technical documentation, • Troubleshoot experiments and contribute to continuous improvement initiatives, • Support a collaborative CRO environment including potential client interaction About You You are a hands-on scientist with experience in skin biology and in vitro model systems, comfortable working in a fast-paced, applied research or CRO environment. You’ll bring: • Experience working with in vitro skin models (essential), • Experience developing RHE (Reconstructed Human Epidermis) models, • Strong laboratory experience across cell-based assays and bioassays, • Knowledge of ELISA, immunoassays, qPCR, and cell culture techniques, • A practical, delivery-focused mindset with strong attention to detail Highly desirable: • Exposure to full-skin equivalent or 3D skin models, • Experience in cosmetic testing, skin ageing, or UV response studies, • Background in CROs or applied commercial research PhD candidates or those with 2–3 years of relevant industry experience are both encouraged to apply. This is a great opportunity to join a growing organisation at a key stage, where you will not only deliver projects but also help shape the future direction of skin model development within the business. Apply now by attaching your CV in Word, or contact Paige Keenan for further information about this new role: paige.keenan@srgtalent.com

Ophthalmology Bioassay Senior Scientist Nottingham | On-site We are seeking an Ophthalmology Bioassay Senior Scientist to join a growing, innovative CRO environment focused on developing next-generation human-relevant disease models. This role sits at the forefront of moving drug discovery away from traditional animal models, with a strong emphasis on advanced in vitro systems, including iPSC-derived models and 3D organoids for ocular diseases. You will play a key role in building and developing capability in ophthalmology, contributing to both project delivery and the longer-term growth of this area of the business. This is an excellent opportunity for someone who enjoys combining hands-on lab work, scientific innovation, and commercial impact. Responsibilities: Ocular Model Development Develop and optimise human-relevant ocular disease models Design and implement iPSC-derived systems, including retinal and epithelial models Contribute to the development of complex 3D organoid and co-culture systemsAssay Development & Delivery Design and execute bioassays relevant to ocular disease, including: Imaging and fluorescence-based assays Immunoassays Functional and translational assays Analyse and interpret experimental data and present findings clearly to stakeholdersMolecular & Cell Biology Apply molecular biology techniques including: Gene knockdown approaches (e.g. siRNA, shRNA) Work with primary cells, cell lines, a...

Skin Bioassay Senior Scientist Nottingham | On-site We are seeking a Skin Bioassay Senior Scientist to join a growing CRO environment developing advanced in vitro skin models and bioassays for both pharmaceutical and cosmetic applications. This role is part of a strategic expansion of in-house skin capabilities, supporting both ongoing projects and the development of new model systems. You will play a key role in generating high-quality datasets, developing human-relevant skin models, and delivering impactful assay results for clients. Working within a collaborative, fast-paced laboratory environment, you will contribute to the development of next-generation skin models, including reconstructed and full-thickness systems, while supporting a broad range of client-driven and internal projects. Responsibilities: Skin Model Development Develop and optimise in vitro skin models, including: Reconstructed Human Epidermis (RHE) models Full-thickness or full-skin equivalent systems Contribute to the evolution of increasingly complex, physiologically relevant modelsAssay Development & Delivery Design and execute cosmetic and skin-related bioassays, including: Cell proliferation and viability assays Cytokine release and inflammatory markers Barrier function and sensitivity assessments Analyse and interpret experimental data, ensuring generation of robust, client-ready datasetsMolecular & Analytical Techniques Apply a range of ...

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