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Manager, Strategic R&D Business Operations Contract Length: 12 months Start Date: January Location: London (Hybrid or Remote) We are supporting a leading global biopharmaceutical organization dedicated to developing transformative therapies for patients with serious and rare genetic conditions. The organisation is seeking an experienced and highly capable Manager, Strategic R&D Business Operations to join its global Research & Development Operations function. This position plays a critical role within the Strategic R&D Business Operations group, serving as a Business Programs Site Manager (BPSM) for assigned clinical programs. The successful individual will be responsible for providing operational leadership across the full lifecycle of clinical site budgets and contracts, ensuring financial accuracy, compliance, and timely execution in support of global clinical trial delivery. Key Responsibilities: • Lead the execution of global site budget and contracting strategies for assigned programs., • Serve as the primary point of contact for site budgets and Clinical Trial Agreement (CTA) management., • Oversee the full lifecycle of site contracts, including drafting, negotiation, amendments, and execution., • Develop clinical trial budget assumptions, financial drivers, and deliver accurate budget analyses., • Create site and country budget templates derived from protocol schedules of assessments, ensuring alignment with fair market value and internal parameters., • Collaborate with Global Study Operations to ensure contracting and budget activities align with overall clinical trial strategy., • Engage proactively with sites, CROs, and vendors to facilitate timely budget negotiations and approvals., • Maintain oversight of CRO/vendor performance related to contracting activities., • Ensure contract version control, documentation accuracy, and compliance with internal systems., • Support site payment reconciliation throughout study maintenance and close-out., • Monitor global regulatory and country-specific requirements related to site budgets, payments, stipends, and contract processes. Minimum Qualifications: • Bachelor’s degree in finance, accounting, health sciences, or a related discipline; advanced degree preferred (experience may substitute for education)., • 8+ years of relevant experience in the pharmaceutical or CRO industry., • 5+ years of direct experience in clinical site contracting and/or clinical budgets within Clinical Operations or Business Operations., • Strong understanding of U.S. and Rest-of-World site contracting practices., • Demonstrated ability to independently manage end-to-end site contracting processes., • Excellent communication skills with the ability to influence stakeholders at all levels., • Proven ability to organize, prioritize, and manage multiple timelines and deliverables., • Strong analytical and problem-solving capabilities, with attention to detail and adherence to ethical standards., • Demonstrated resilience in dynamic environments and ability to propose solutions to complex challenges. How to Apply: Qualified candidates with relevant experience in clinical contracting, budgeting, and R&D business operations are encouraged to apply. Please submit your CV or contact us directly!

AVEVA is creating software trusted by over 90% of leading industrial companies. Job Title: VP - R&D – AI Core Services Development Location: Cambridge, London, UK (Hybrid) Type: Full-Time About The Role We are searching for an accomplished Software Development Leader to build and lead the development of core AI Services for our Industrial Intelligence Software Platform. In this role, you will be responsible for delivering secure, reliable, highly available, and scalable platform services that will serve as foundational building blocks for AI capabilities across AVEVA’s product portfolio and partner ecosystem. These services will power intelligent industrial solutions at global scale. You will lead a talented team of engineers to architect, build, and evolve distributed cloud-native services and public APIs that enable democratized access to AI capabilities, accelerating innovation and adoption across domains, technology teams, and external partners. We are specifically keen on individuals who have experience within start-up type environments. Key Responsibilities: Platform Services Development • Drive the Execution, Design, and Build of Core AI services that are scalable, reusable, secure, reliable, and highly available., • Ensure the Core AI Services (Orchestration, SDKs, etc.) are extensible and allows contribution on a federated model to accelerate scalability within AVEVA., • Ensure Core AI services are sustainable and follow best practices for validation, continuous, delivery, disaster recovery, etc. Democratization & Adoption • Drive adoption and reuse of core AI services by AVEVA product and capability teams, • Enable self-service access, reference implementations, and integration toolkits to lower the barrier to entry., • Engage with other execution leaders and collaborate with enablement teams to support Core AI adoption. Security, Compliance & Regulations • Embed security and privacy-by-design practices into all services and APIs., • Ensure compliance with global AI regulations and emerging governance frameworks., • Establish processes for responsible AI, model explainability, observability, and auditability. AI & Cloud Expertise • Provide strong execution leadership in AI and cloud-native software development, • Guide the use of modern AI frameworks, data pipelines, inference engines, and orchestration platforms., • Collaborate with Product Managers and Architects and to translate industrial AI use cases into services capabilities. Team Leadership & Execution • Build and lead a high-performing, cross-functional development team with a strong culture of engineering excellence., • Foster a builder mindset within the team — encouraging rapid prototyping and continuous improvement with agility of a start-up, • Foster a collaborative environment across geographies, time zones, and technical disciplines. Core Skills and Qualifications: • 20+ years of experience in software product development, with 10+ years in leadership roles focused on development of cloud-native platforms or AI services, • Proven experience building distributed, secure, and scalable cloud/AI services (ideally on Microsoft Azure) which accelerate value delivery to customers, • Solid background in AI/ML technologies, including experience in AI models and tools, • Strong knowledge of public API design and service lifecycle management., • Familiarity with the latest AI standards including Model Context Protocol (MCP) and Agent2Agent (A2A), • Familiarity with AI regulations (EU AI Act, NIST AI RMF) and responsible AI principles., • Excellent stakeholder engagement, collaboration, and communication skills. What Success Looks Like: • Scalability, Reliability, Availability, and Security of core AI services in production., • Adoption of services by internal product/capability teams and external partners., • Developer experience and ease-of-use of AI Services APIs., • Compliance with applicable AI governance and regulatory requirements., • Engagement and growth of the core AI services team. R&D at AVEVA Our global team of 2000+ developers work on an incredibly diverse portfolio of over 75 industrial automation and engineering products, which cover everything from data management to 3D design. AI and cloud are at the centre of our strategy, and we have over 150 patents to our name. Our track record of innovation is no fluke – it’s the result of a structured and deliberate focus on learning, collaboration and inclusivity. If you want to build applications that solve big problems, join us. UK Benefits include: Flexible benefits fund, emergency leave days, adoption leave, 28 days annual leave (plus bank holidays), pension, life cover, private medical insurance, parental leave, education assistance program. It’s possible we’re hiring for this position in multiple countries, in which case the above benefits apply to the primary location. Specific benefits vary by country, but our packages are similarly comprehensive. Find out more: aveva.com/en/about/careers/benefits/ Hybrid working By default, employees are expected to be in their local AVEVA office three days a week, but some positions are fully office-based. Roles supporting particular customers or markets are sometimes remote. Hiring process Interested? Great! Get started by submitting your cover letter and CV through our application portal. AVEVA is committed to recruiting and retaining people with disabilities. Please let us know in advance if you need reasonable support during your application process. Find out more: aveva.com/en/about/careers/hiring-process About AVEVA AVEVA is a global leader in industrial software with more than 6,500 employees in over 40 countries. Our cutting-edge solutions are used by thousands of enterprises to deliver the essentials of life – such as energy, infrastructure, chemicals, and minerals – safely, efficiently, and more sustainably. We are committed to embedding sustainability and inclusion into our operations, our culture, and our core business strategy. Learn more about how we are progressing against our ambitious 2030 targets: sustainability-report.aveva.com/ Find out more: aveva.com/en/about/careers/ AVEVA requires all successful applicants to undergo and pass a drug screening and comprehensive background check before they start employment. Background checks will be conducted in accordance with local laws and may, subject to those laws, include proof of educational attainment, employment history verification, proof of work authorization, criminal records, identity verification, credit check. Certain positions dealing with sensitive and/or third-party personal data may involve additional background check criteria. AVEVA is an Equal Opportunity Employer. We are committed to being an exemplary employer with an inclusive culture, developing a workplace environment where all our employees are treated with dignity and respect. We value diversity and the expertise that people from different backgrounds bring to our business. AVEVA provides reasonable accommodation to applicants with disabilities where appropriate. If you need reasonable accommodation for any part of the application and hiring process, please notify your recruiter. Determinations on requests for reasonable accommodation will be made on a case-by-case basis.

About The Role UNLOCK YOUR BEST WORK LIFE • MAKE A DIFFERENCE FOR EVERY PATIENT We’re looking for an enthusiastic and clinically driven Specialist Clinical Pharmacist to join our Pharmacy team at Practice Plus Group Hospital, Ilford on a fixed-term contract, up to 12 months. Working 22.5 hours per week, you’ll play a key part in delivering safe, patient-focused pharmacy services across a range of elective specialities including Orthopaedics, ENT, Urology, Gynaecology, Ophthalmology and Endoscopy. This is a brilliant opportunity to work within a friendly, supportive hospital environment with excellent facilities, a strong governance focus, and a reputation for outstanding patient outcomes. Whether you are an experienced hospital pharmacist or looking to grow into advanced clinical practice, you’ll be joining a team committed to continuous improvement, professional development, and collaborative working. What you'll be doing As our Specialist Clinical Pharmacist, you will be involved in delivering high-quality clinical pharmacy and medicines management services, including: • Providing clinical ward cover, dispensary support and expert advice to consultants, nursing teams and patients., • Screening prescriptions, reconciling medicines, reviewing drug charts and ensuring safe, effective and evidence-based use of medicines., • Supporting the development of enhanced recovery pathways, antimicrobial stewardship, VTE prevention and perioperative medicines optimisation., • Participating in MDT meetings, ward rounds and outpatient services., • Contributing to governance activities such as audits, formulary reviews, incident learning and protocol development., • Working closely with the Site Lead Pharmacist to maintain high standards of clinical quality, patient safety and medicines legislation compliance., • Providing training, guidance and medicines management education to clinical colleagues., • Supporting the design of new processes and digital approaches to improve workflow, safety and patient experience. What we'll look for in you We’re seeking a motivated, knowledgeable pharmacist who can bring a patient-centred and solutions-focused approach. You’ll ideally have: • Master’s degree in Pharmacy (MPharm or equivalent) and GPhC registration, • Postgraduate Clinical Pharmacy Certificate or willingness to work toward this, • Experience as a clinical pharmacist with a good understanding of hospital or multidisciplinary care, • Strong clinical reasoning skills and the ability to apply evidence-based practice, • Sound knowledge of therapeutics, NICE guidance and current hospital pharmacy practices, • Excellent communication skills, able to influence and collaborate effectively across teams, • A positive, proactive mindset with a commitment to continuous improvement and safe patient care In return we offer; • A salary up to £54,000 per annum pro rata based on skills and experience, • A wide range of wellbeing and lifestyle benefits, • Work 22.5 hours a week, • 25 days annual leave plus bank holidays pro rata, • A fixed-term contract up to 12 months To apply for the role, click on the link below. If you have any questions, contact Our employment offers are subject to receipt of satisfactory pre-employment checks. At Practice Plus Group, we actively promote diversity and equal opportunities. Applicants must have the right to work in the UK.

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Site Name: USA - Massachusetts - Waltham, Switzerland - Zug, UK - London, USA - Pennsylvania - Pennsylvania Central, Warsaw Posted Date: Dec 11 2025 At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together. Find out more: ___The Medical Director Oncology Clinical Development, Breast and Gynecologic Cancers will report to the Executive Medical Director, Clinical Development Lead (CDL), Oncology Clinical Development. The Medical Director will be responsible for clinical research activities pertaining to advancing the development of GSK’s clinical portfolio and will also have responsibility for engaging in medical dialogues with relevant scientific and medical leaders so as to lead clinical data generation activities. This individual will also have a leading role in managing effective relationships with Key External Experts. This position will support our growing oncology antibody drug conjugate (ADC) portfolio for the treatment of solid tumors. The incumbent will have the opportunity to work across early to late-stage development and in partnership with a multi-disciplinary team of oncology drug developers. An on-site office presence for a minimum of two days a week is required in one of GSK’s UK (London or Stevenage), US (PA or MA), Switzerland (Zug) or Poland (Warsaw) campuses. Key Responsibilities • Collaborate with physicians, scientists, regulatory professionals, biostatisticians, regulatory, executive staff and others in a complex matrix environment to develop and execute phase 1-3 interventional clinical trials, • Ensure high quality protocol development aligned with the Clinical Development Plan to effectively determine a medicine’s potential efficacy, safety profile, key areas of product differentiation and value to patient in the shortest possible timeframe., • Use medical expertise to contribute to the end to end (protocol concept to final study report) to ensure scientific integrity and timely delivery of clinical trials which ensure consistency with the clinical development strategy for regulatory approvals, reimbursable medicines, and successful lifecycle management; demonstrate ability to incorporate global considerations into decision making, • Interpret and summarize study results consistent with objectives to define safety, efficacy, pharmacokinetic/pharmacodynamic, and patient reported outcomes, and applicability of data to the targeted patient population., • Assume medical responsibility for clinical trials with active participation in real-time medical monitoring of studies, including patient eligibility assessment, study design questions, and addressing urgent safety questions (with inclusion of Safety/ PV as relevant)., • Assume responsibility for medical review of clinical trial data, both directly as needed and/or via oversight of delegated medical review. Oversee blinded review of data packages intended for IDMCs., • Review/monitor safety data in collaboration with pharmacovigilance group for active clinical studies., • Participate in the authoring of clinical study reports and regulatory documents and collaborate with colleagues in Regulatory Affairs, CMC, Toxicology, Research, Pharmacology to respond to health authority and ethics committee queries., • Collaborate with Principal Investigators in the evaluation and assessment of publications (abstracts, posters, manuscripts) associated with clinical data., • Network extensively to develop long-term strategic partnerships with thought leaders both internally and externally, in support of GSK’s vision., • Understand biological mechanisms, clinical strategy, scientific interpretation of disease and target-based literature., • Serve as a core member of the Clinical Matrix Team for one or more assets in development., • Represent Clinical Development on disease area strategy, integrated evidence and medical affairs strategy teams., • Participate in Oncology Clinical Development-wide initiatives and workstreams as appropriate. Why You? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: • Medical degree from accredited medical school, • Completion of a clinical residency program, • Clinical experience in medical oncology, hematology, or gyn oncology, • Experience in clinical research and development Preferred Qualifications: If you have the following characteristics, it would be a plus: • Oncology clinical research and drug development experience focused on Gynecologic Cancer or Breast cancer, • Experience in the pharmaceutical/biotechnology industry; clinical academic medicine or clinical medical practice settings in the field of oncology or gynecologic oncology., • Oncology clinical drug development process experience in the conduct/participation of clinical trials (investigator initiated, company sponsored or cooperative group trials) and their subsequent publications., • Regulatory experience to support registration and GCP principle, • Robust knowledge of disease-specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution, • If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $222,750 to $371,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process. Please visit ___ to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call. Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the ___ where you will find answers to multiple questions we receive GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at ___

Summary LOCATION: London or Dublin or Basel ROLE TYPE: Hybrid Working, The Clinical Development Director (CDD) is the clinical/scientific and clinical development expert and provides leadership and support to clinical development deliverables and activities within a defined global clinical development program and/or global clinical trial (e.g. clinical development plan, clinical trial protocol), under the leadership of the GPCH. About The Role Major accountabilities: • Supports and if assigned leads delivery of all assigned clinical deliverables in the assigned section of a clinical program. Clinical deliverables may include the clinical development strategy for assigned program section(s), clinical sections of individual protocols consistent with the Integrated Development Plans (IDP), clinical data review and program specific standards, clinical components of regulatory documents/registration dossiers, and publications, • Provides input into final analyses and interpretation including the development of the Clinical Study Report(s) (CSRs), publications and internal/external presentations., • Leads development of clinical sections of trial and program level regulatory documents (e.g., Investigator’s Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities), • Oversees/conducts ongoing clinical and scientific review of clinical trial data with medical monitor, Clinical Scientific Expert(s) with appropriate oversight from Medical Lead. Work in close collaboration with the data management and statistics teams to ensure proper data quality and analysis of clinical trial results., • Inspection Readiness and interaction with QA - risk assessments, audit preparation, mock interviews, storyboard and presentation prep; Author and/or review abstracts, presentations and manuscripts for accuracy of clinical data and content, • May be the Program Manager of other associates (e.g., CSE), • Provides support to Sr CDMD and/or GPCH in monitoring and safety data and signals the molecule for the assigned section of the clinical trial, may be a member of the Safety Management Team (SMT), and supports overall program safety reporting (e.g., Periodic Safety Update Reports (PSURs), Drug Safety Update Reports (DSURs), and other safety related documents) in collaboration with the medical monitor, CDMD and Patient Safety, • As a clinical development expert, may support the GPCH or CDH in interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring boards, advisory boards, patient advocacy groups), internal stakeholders (e.g., CTT, Research, Translational Medicine, Global Medical Affairs, Marketing, HE&OR), and internal decision boards, • May work with Biomedical Research/Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as assigned, • Ensures career development of Program reports and other clinical colleagues through active participation in the performance management and talent planning processes. Provides on-boarding, training, & mentoring support, • Contributes to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise medical/scientific training, • May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives), • May be assigned to lead clinical trial(s) as Clinical Scientific Lead and provide leadership and guidance for all clinical aspects of a clinical trial in close collaboration with the assigned medical monitor and/or CDMD. Education (minimum/desirable) • Advanced degree in life sciences/healthcare (or clinically relevant degree) is required. PharmD, or PhD strongly preferred, • Background or experience in Neuroscience, Neurodegeneration, Neuromuscular, Gene Therapy, Rare diseases, Neuroinflammation or similar required., • Languages: Fluent oral and written English Experience/Professional Requirement • ≥ 7 years of involvement in clinical research or drug development in an academic or industry environment spanning clinical activities in Phases I through IV. ≥ 3 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry, • Advanced knowledge of assigned therapeutic area, • Demonstrated ability to establish strong scientific partnership with key stakeholders, • Thorough knowledge of GCP, clinical trial design and methodology, statistical analysis methodology, and regulatory/clinical development process, • Excellent communication skills, written and oral, • Excellent interpersonal skills, • Excellent negotiation and conflict resolution skills Commitment To Diversity And Inclusion Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? ___Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: ___

Affirm is reinventing credit to make it more honest and friendly, giving consumers the flexibility to buy now and pay later without any hidden fees or compounding interest. Do you love being in the middle of it all? Are you as excited to tackle technical problems as you are to build critical client relationships? As a Staff Technical Account Manager, you will be integral to the technical success of our largest merchants in a new geographical market, guiding their developers, product teams, and key business partners throughout the entire customer lifecycle. Your responsibilities will include solution selling and implementing our products into merchants' existing architectures, as well as providing ongoing support as they scale. You will not only help them mitigate potential issues but also empower them to leverage the full spectrum of Affirm’s offerings, translating business objectives into technical strategies and product optimizations. Technical Account Managers are part of the Engineering Team and collaborate closely with Affirm’s Product, Operations, Customer Success, and Frontline Technical Support teams. What You’ll Do • Be the primary technical lead over a set of key merchants in a new geography. Be responsible for building the trust of your technical counterparts while also fostering long term relationships with all merchant partners, • Project Manage and provide world class technical guidance and solutions for new merchants’ integrations and post launch expansion initiatives; utilize and build on implementation guides, best practice playbooks, troubleshooting, and UAT certification plans, • Work closely with Commercial team counterpart(s) on establishing overall account strategy based on business goals and opportunities, and selling solutions to new prospects., • Support clients through their lifetime as Affirm partners; quickly resolve critical technical issues for your accounts; quarterback multi-departmental efforts to resolve complicated issues in a timely manner, • Provide early feedback to engineering and product teams while iterating on new products What We Look For • Experience: 7+ years in a client-facing technical role, such as a Technical Account Manager, Solutions Engineer, Sales Engineer, or Integration Engineer, preferably within a SaaS or FinTech environment., • API Expertise: Deep understanding of RESTful APIs, webhooks, and the HTTP protocol. Hands-on experience using API testing tools like Postman to debug and validate integrations is essential., • Coding Literacy: Proficiency in reading and understanding production-level code. You should be comfortable with HTML, JavaScript and SQL and ideally one server-side language (e.g. Python)., • Web & Mobile Architecture: A solid grasp of modern web and mobile application architecture, including client-server models, front-end frameworks, and the role of SDKs., • Troubleshooting Acumen: Proven ability to diagnose and solve complex technical problems using a standard toolkit, including browser developer consoles, log analysis platforms (e.g., Snowflake, Chronosphere), and ticketing systems (e.g., Jira, Notion)., • Communication: Exceptional communication skills, with a deep command of the written word (please submit a cover letter when applying - we actually read them!), • Education: Bachelor’s degree with a record of pushing yourself academically or equivalent practical experience Nice To Have • Degree in a technical major (Computer Science, Mathematics, Engineering, etc.) or bootcamp grad, • Familiarity with the payments ecosystem, • Familiarity with web/mobile application architecture, • Comfortable writing code in at least one language Pay Grade - N Equity Grade - 5 Employees new to Affirm typically come in at the start of the pay range. Affirm focuses on providing a simple and transparent pay structure which is based on a variety of factors, including location, experience and job-related skills. Base pay is part of a total compensation package that may include monthly stipends for health, wellness and tech spending, and benefits (including 100% subsidized medical coverage, dental and vision for you and your dependents). In addition, the employees may be eligible for equity rewards offered by Affirm Holdings, Inc. (parent company). GBR base pay range per year: £117,000 - £157,000 Please note that visa sponsorship is not available for this position. Affirm is proud to be a remote-first company! The majority of our roles are remote and you can work almost anywhere within the country of employment. Affirmers in proximal roles have the flexibility to work remotely, but will occasionally be required to work out of their assigned Affirm office. A limited number of roles remain office-based due to the nature of their job responsibilities. Benefits We’re extremely proud to offer competitive benefits that are anchored to our core value of people come first. Some key highlights of our benefits package include: • Health care coverage - Affirm covers all premiums for all levels of coverage for you and your dependents, • Flexible Spending Wallets - generous stipends for spending on Technology, Food, various Lifestyle needs, and family forming expenses, • Time off - competitive vacation and holiday schedules allowing you to take time off to rest and recharge, • ESPP - An employee stock purchase plan enabling you to buy shares of Affirm at a discount We believe It’s On Us to provide an inclusive interview experience for all, including people with disabilities. We are happy to provide reasonable accommodations to candidates in need of individualized support during the hiring process. [For U.S. positions that could be performed in Los Angeles or San Francisco] Pursuant to the San Francisco Fair Chance Ordinance and Los Angeles Fair Chance Initiative for Hiring Ordinance, Affirm will consider for employment qualified applicants with arrest and conviction records. By clicking "Submit Application," you acknowledge that you have read Affirm's ___ and hereby freely and unambiguously give informed consent to the collection, processing, use, and storage of your personal information as described therein.

Location: Fully Remote (Dubai, UK, Europe time zones (GMT+4 focus)) About the Company Our client is a leading global liquidity and technology provider with over 10 years of experience, specializing in B2B solutions for the FX and Crypto industries. We deliver cutting-edge technology solutions that enable brokers, exchanges, and financial institutions to scale faster while minimizing infrastructure costs. Overview of the Role We are seeking a highly skilled and technically proficient FX Liquidity Platform Engineer with deep hands-on experience in the retail and institutional FX brokerage infrastructure. This is a hybrid, hands-on role combining advanced technical diagnostics (FIX, Network) with critical operational and financial responsibilities (Reconciliation, Onboarding). You will be responsible for the configuration, rapid diagnosis, and seamless operation of our core Liquidity Hubs. 🔑 Key Responsibilities (Hands-on Focus) • Full Onboarding Lifecycle: End-to-end configuration and deployment of new institutional client connections, including Direct FIX Connectors, MT4/MT5 Bridge Connectors, and Giveup (Dropcopy) Connections for reporting., • Hub Administration: Daily monitoring, maintenance, and assurance of 99.9% uptime for critical Liquidity Hubs., • Conformance Testing (Critical): Execution of the full Conformance Testing cycle for both Taker API and Maker API across OneZero (OZ) and PrimeXM (PXM) to ensure new partner readiness., • FIX Protocol Expertise: In-depth knowledge of FIX Protocol (message structure, tags, sessions) and advanced troubleshooting of FIX connectivity issues., • Network & Latency Diagnostics: Rapid identification and resolution of network latency issues, utilizing tools like traceroute and telnet tests to diagnose TCP/IP connectivity., • API Systems: Troubleshooting and performing connectivity tests for integrations based on REST API and messaging queues (RabbitMQ or Kafka)., • Emergency Management: Execution of escalation procedures, quick reaction, and effective troubleshooting during critical system outages., • Reconciliation: Conducting critical daily reconciliation of the Coverage Account against the Margin Account within the Hubs., • Process Ownership: Full handling of Compensation Cases from initial analysis through to final settlement (A-Z)., • Hubs Expertise (Critical): Direct, hands-on experience with any of the key Liquidity Hubs: OneZero (OZ), PrimeXM (PXM), Centroid, or FXCubic., • Connectivity & Protocol: Expert level knowledge of FIX Protocol and practical experience with REST API / RabbitMQ (or Kafka)., • Trading Systems: Proven experience with MT4/MT5 Connector/Bridge technology and administration., • Diagnostics: Proven network troubleshooting skills (e.g., using traceroute, telnet) and Latency monitoring., • Experience in the FinTech sector – Must have., • Advanced knowledge of MySQL for complex querying, custom reporting, and Reconciliation tasks., • Certification or extensive experience in MetaTrader Administration., • Competitive salary based on knowledge and experience., • 24 days of annual leave (as per group policy)., • Fully remote position with flexible working arrangements., • Support for continuing education, blockchain certifications, and regulatory training (after one year of service).

Job Description Summary The role of a Clinical Education Specialist is primarily to deliver and co-ordinate training on GE Healthcare’s products. This training is mainly delivered at a hospital site but also remotely using digital methods. The Clinical Education Specialist owns support within the IGT install base. GE Healthcare is a leading global medical technology and digital solutions innovator. Our mission is to improve lives in the moments that matter. Unlock your ambition, turn ideas into world-changing realities, and join an organization where every voice makes a difference, and every difference builds a healthier world. GE HealthCare is a leading global medical technology and digital solutions innovator. Our purpose is to create a world where healthcare has no limits. Unlock your ambition, turn ideas into world-changing realities, and join an organization where every voice makes a difference, and every difference builds a healthier world Responsibilities Job Description • You will provide onsite clinical applications training to user’s equipment in given modality area, • You co-ordinate installations and initial clinical applications alongside sales, service and the Clinical Education Manager, • You will be the technical liaison to the sales organization with the goal of strengthening technical capabilities of the team and customer relationships, while also driving business opportunities forward, • You conduct high quality application trainings at customer sites to ensure customer's safe and effective use of GE equipment’s, maximizing image quality and productivity, • You will maintain satisfactory after-sale relationships and development of long-term customer relationships coupled with the ability to identify and capitalize on opportunities that immediately satisfy customer needs, • You promote unique differentiators based on customer's clinical needs, competition, values and benefits sought, • You continuously develop and improve a network of key opinion leaders within the assigned territory, • You support Trade show/Workshops/show sites/Customer visits, • You support the deployment of digital tools and embrace the digital transformation of clinical education, • You document trainings, site visits and Customer interactions as per the local protocol., • Deliver customer presentations at Classroom Education days and user event Qualifications • You bring a Degree as a certified Radiographer, • You have proven technical/clinical industry experience with Surgery/C-arms, • You have proven experience in theatre procedures and C-arms usage, • You bring excellent interpersonal skills including, team working skills and good communication skills, • You are self-motivated and have the willingness to take the initiative to identify opportunities for improvement and take actions to improve, • You are team oriented and have a strong customer satisfaction mindset, • You are not afraid of being flexible/adapt to changing work environments, • You are able to travel and be at customer sites 70 to 80% of the working time (annual average) Desired Skills • You have already worked with GE products, • You are experienced in conducting training, • You bring a first knowledge of GE’s or competitor’s Interventional products Inclusion and Diversity GE HealthCare is an Equal Opportunity Employer where inclusion matters. Employment decisions are made without regard to race, color, religion, national or ethnic origin, sex, sexual orientation, gender identity or expression, age, disability, protected veteran status or other characteristics protected by law. Behaviors We expect all employees to live and breathe our behaviors: to act with humility and build trust; lead with transparency; deliver with focus, and drive ownership – always with unyielding integrity. Total Rewards Our total rewards are designed to unlock your ambition by giving you the boost and flexibility you need to turn your ideas into world-changing realities. Our salary and benefits are everything you’d expect from an organization with global strength and scale, and you’ll be surrounded by career opportunities in a culture that fosters care, collaboration and support. Additional Information Relocation Assistance Provided: No

About Us GeneEase discovers novel gene therapies for subclinical conditions overlooked by traditional medicine - genetic disorders affecting millions (alcohol intolerance, lactose intolerance, mild autoimmunity) where existing treatments are inadequate or nonexistent. We use computational biology to identify promising therapeutic targets, design gene therapy approaches (AAV, base editing, other modalities), validate mechanisms in silico, and partner with wet labs for experimental confirmation. We file patents and license IP to gene therapy companies for clinical development. Role Overview Lead computational gene therapy development: design therapeutics that can be manufactured, delivered, and clinically translated - not just theoretically promising targets. You'll evaluate targets, design vectors with practical constraints in mind (manufacturability, delivery, immunogenicity), validate in silico, and coordinate academic partnerships for experimental validation. 80% computational work, 20% wet lab coordination. You design experiments—partners execute them. Critical: You must understand what makes gene therapies succeed or fail in practice, not just in silico. Key Responsibilities Therapeutic Design with Translational Focus (40%) • Evaluate genetic targets (genetic clarity, deliverability, market size), • Design gene therapy approaches considering practical constraints:Manufacturability: AAV titer requirements, production scalability, purification, • Deliverability: Tissue accessibility, dose requirements, injection volumes, immunogenicity, • Regulatory feasibility: IND pathway, safety assessment, clinical endpoint definition, • Select modality (AAV, base editing, other), vector/delivery system, regulatory elements, • Protein modeling: Structure prediction (AlphaFold), molecular dynamics (GROMACS), enzyme kinetics, • Safety assessment: Biodistribution (PBPK), immunogenicity, off-target prediction, • Translational risk assessment: Therapeutic window, dose-response, durability predictions, • Identify labs with relevant capabilities (animal models, assays, AAV production), • Design experimental protocols considering practical feasibility (realistic timelines, achievable titers, appropriate controls), • Draft manuscripts, patent applications, pharma partner dossiers emphasizing clinical translatability Requirements Education: PhD in Computational Biology, Bioinformatics, Bioengineering, Systems Biology, or related fields (or MS with 3-5 years experience) Wet Lab Experience: 1-3 years hands-on experience (cloning, cell culture, transfection, assays). Gene therapy experience strongly preferred (AAV/lentivirus production, transduction, functional validation, titer quantification). Gene Therapy Technical: Vector design (AAV serotypes, promoter selection, cargo optimization, CRISPR guide RNAs), tools (Benchling, SnapGene) Gene Therapy Development Mindset: • Understand what makes vectors succeed vs. fail in practice (not just in silico), • Consider manufacturability, deliverability, and immunogenicity upfront Programming: Python (BioPython, pandas, PyTorch), R (Bioconductor), SQL, Git, Linux/HPC Nice-to-Haves • Gene therapy industry experience: Worked at gene therapy biotech in vector development, process development, or CMC roles, • IND-enabling study experience: Familiarity with GLP tox, biodistribution studies, dose escalation strategy, • AAV manufacturing knowledge: Production optimization, titer improvement, purification troubleshooting, • Academic/CRO partnership management: Protocol transfer, feasibility assessment, troubleshooting, • Regulatory awareness: IND/CTA filings, FDA feedback meetings, clinical endpoint selection Essential Traits • Autonomous problem-solver with mechanistic thinking, • Bridges computational predictions with biological reality, • Builds tools, not just uses them, • Communicates complex work to non-technical stakeholders Why Join Us • Shape the foundation of a product that bridges biology and computation., • Collaborate with a global, interdisciplinary team., • Flexible, remote-first engagement., • Opportunity to see your expertise directly influence product development. How to Apply Please submit your application at: We look forward to hearing from you!

Flexible supply/PPA teacher required for primary schools in Croydon Are you a primary school teacher looking for a good work life balance? We're looking for flexible Supply/PPA teachers in to do just that, while avoiding the responsibilities of being a full-time class teacher. Qualified Teacher

What we’re looking for Teachers who: Put children’s wellbeing at the centre of their day Build warm, trusting relationships with pupils and families Move between year groups with confidence and calm Bring consistent behaviour management Enjoy the variety and buzz of supply work Wh

What you’ll be doing: Championing pupils by providing calm and consistent 1:1 support Putting plans into action, helping teachers deliver tailored learning that really works Keeping students engaged and breaking tasks down so every child can succeed Managing tricky moments with positivity

You will receive excellent rates of pay and an designated Consultant who has worked for Protocol for over 10 years. Please see the FAQs on the Protocol Education website for further details.

About the Role: Provide high-quality teaching across primary and/or secondary settings Deliver engaging lessons and maintain a positive classroom environment Adapt quickly to different schools, year groups, and subjects Ensure continuity of learning in the absence of the class teacher What We&r

SEN Teaching Assistant – Croydon Location: Croydon Start Date: ASAP Contract Type: Full-time / Long-term Protocol Education is seeking a dedicated and compassionate SEN Teaching Assistant to join one of our partner schools in Croydon.

Please see the FAQs on the Protocol Education website for further details.

What the School Offers Supportive and collaborative Science faculty with modern labs Excellent behaviour policies and engaged students CPD opportunities and career progression routes OFSTED “Good” with outstanding leadership Your Role Deliver engaging Chemistry lessons across KS3&n

KS1 Class Teacher (Year 1 & 2) Job Title: KS1 Class Teacher Location: Wembley, NW, London Start Date: Immediate Job Type: Full Time, Long term, Term-to-Perm, Supply Teacher Salary: Pay to scale Key Responsibilities: * Deliver engaging and creative lessons in line with the KS1 curriculum * Create

Reception Teacher – Brent Full-Time | January 2026 Start | Let’s Make Learning Stick Looking for a new chapter in your teaching journey? A vibrant primary school in Brent is on the lookout for a passionate, organised, and inspiring Reception Teacher to join their te

A progressive school in Edmonton is looking to appoint a SEN Teaching Assistant to work with KS2 children with SEMH and ASD needs.This position starts January 2026 - July 2026.You will be working 121 and with small groups of children under the guidance of the Class Teacher.The school is rated &lsquo

Secondary Daily Supply Support Staff / Long-term roles– Flexible Work Location: London Pay: Dependant on Experience Contract: Flexible, Part-time / Minimum 2 days per week Want work that fits around you? Join our supply support staff team and choose when and where you work across London.

You must have recent experience working in a Primary School setting with KS1/KS2 children however all Primary School experience will be considered*** Monday-Friday 8:30-16:00 Start date - January 2026 We Offer: Excellent weekly pay, paid into your account every Friday Dedicated consultant who w

Nursery Teacher – Full Time – Haringey Start Date: January| Inner London MPS1 to MPS6 | ECTs Welcome Are you a passionate and nurturing Nursery Teacher looking to inspire the youngest learners? We are working with a supportive and welcoming primary school in the borough of Haringey who

EYFS Level 3 Teaching Assistant Location: Hampton Court/ Kingston/ Sunbury Contract Type: Full-Time Start Date: November 2025 About Us: Protocol Education are seeking a wonderful Level 3 Early Years qualified.

SEND Teaching Assistant – Ruislip (High Needs Support) £95–£105 per day | Immediate Start | Full Time Are you an experienced SEND Teaching Assistant with a strong background supporting high-needs pupils? I’m looking for someone confident, patient and skilled to join a

Design Technology Teacher (Engineering Focus) Location: Barnet, North London Salary: MPS/UPS (Outer London Weighting) Start Date: January 2026 Contract: Full-time, Long-term / Permanent Are you a forward-thinking Design Technology Teacher with a passion for Engineering? Do you want to teach

Sound like your kind of place? What the role involves: 1:1 support for a KS1 pupil with autism and ADHD Working closely with the class teacher and SENCO to adapt learning Using structure, patience and creativity to build engagement Helping the pupil regulate, access the curriculum and build confid

Primary Teachers – Full & Part Time Roles in Watford Location: Watford, Hertfordshire Start: ASAP or January 2026 Contract: Full-time or Part-time Salary: £140–£160 per day (PAYE – no umbrella faff) Love teaching but not the stress? Join Protocol Education and wo

Graduate Teaching Assistant – Start Your Education Career With Impact! Location: Kingston Salary: competitive Contract: Full-time/ Term-time Are you a recent graduate eager to kick-start a meaningful career? Do you want a role where every day you make a difference — while

As a Cover Supervisor you will need the ability to control a classroom, think on your feet and ultimately be able to quickly make an impression on the children and build rapport.As a Cover Supervisor you are a replacement for the teacher for that day and all the learning material is predetermined, y

Location: Islington, London Position: Early Years Teacher Contract Type: Full-time Start Date: January 2026 About the Role: A forward-thinking and inclusive Early Years setting in Islington are seeking a dynamic and enthusiastic Early Years Teacher to join their teaching team from January 2026. You

What you’ll be doing Providing flexible cover across EYFS, KS1 and KS2 Leading small group interventions and occasional whole-class teaching Helping to create a positive, inclusive learning environment rooted in the school’s Catholic values Working closely with teachers and support s

Experienced Special Needs Teaching Assistant Job Duties: * Provide support to students with special educational needs such as ASC, PMLD, SLD, and behaviours that challenge * Assist in the implementation of Education Health Care Plans (EHCP) for students * Help students with personal care and m

SEMH Teaching Assistant (Social, Emotional & Mental Health) Pay: £90–£110 per day (PAYE – absolutely no umbrella companies) Location: Barking & Dagenham Contract: Full-time / Long-term Do you have a natural instinct for supporting children who just need someone to truly s

Please see the FAQs on the Protocol Education website for further details. Protocol Education is committed to safeguarding and promoting the welfare of children. For details of our privacy policy, please see visit the Protocol Education website.

If you're ready to bring enthusiasm, expertise, and a growth mindset to an exciting teaching opportunity, apply today to become part of a forward-thinking and supportive team.

Qualified teacher with a Computer Science specialism. Proven experience teaching A Level Computer Science. We are seeking an exceptional Computer Science teacher to join our dynamic department, teaching across Key Stages 3, 4, and 5.

We undertake safeguarding checks on all workers in accordance with the DfE statutory guidance ‘Keeping Children Safe in Education’, this may also include an online search as part of our due diligence on shortlisted applicants. We offer FREE online safeguarding and Prevent Duty training to all ou

Want the joy of teaching—minus the long-term pressure?.We’re looking for adaptable, enthusiastic.Whether you’re in between roles, balancing other commitments, or just prefer flexibility, this is your chance to teach your way—with local schools and zero planning panic.You&rsqu

We offer FREE online safeguarding and Prevent Duty training to all our workers. The role involves working with students who need additional behavioural support, helping to implement strategies to encourage positive learning behaviours. We undertake safeguarding checks on all workers in accordance wi

Teacher of Religious Education.Are you a dynamic and passionate Teacher of RE? We have an exciting opportunity for an enthusiastic educator to join our vibrant and motivated RE department.This is a fantastic chance to contribute to the academic success and personal development of our students in a n

Qualified Teacher Status (QTS). If you are an MFL Teacher ready for a new challenge in. MFL Teacher – Outstanding School in Barnet – January Start.

Join this excellent, supportive, and well-resourced department with a remarkable track record in developing both students and staff.This School is committed to offering outstanding CPD programs, collaboration opportunities with other schools, personalized coaching, and a proven track record of caree

We are seeking a proactive and dedicated Attendance Officer to support and improve student attendance. Key Responsibilities:Attendance Officer.

We are pleased to offer a fantastic opportunity to join our vibrant and dynamic Art & Photography department. Teacher of Art & Photography. Whether you are an Early Career Teacher (ECT) looking to make your mark, or an experienced educator seeking a new challenge, we welcome your application

We are seeking a passionate and dedicated Teacher of English to join our vibrant and high-achieving secondary school in the heart of Camden. You will be joining a forward-thinking and collaborative English department that fosters a love of literature, creative writing and analytical thinking. A stro

The school is looking for a passionate and hardworking KS2 Teacher to join the school and support students with a range of special educational needs , ASC, ADHD and SLCN. A school committed to the learning and wellbeing of the students. We undertake safeguarding checks on all workers in ac