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The Department of Chemistry at Columbia University is looking to fill the position of Associate Research Scientist or Research Scientist in the Gonzalez research group. The successful candidate will have extensive experience in molecular biology, biochemistry, molecular biophysics, single-molecule biophysics, and/or fluorescence microscopy, with preference given to applicants with experience working with ribosomes, RNA, and/or membrane proteins and/or using single-molecule biophysics and/or fluorescence microscopy. Moreover, the successful candidate will be passionate about the communication of complex scientific concepts and have strong writing skills. In addition, the successful candidate will have a strong interest in the training and mentoring of junior scientists. Responsibilities will include assisting in the design, direction, performance, and oversight of independent projects aimed at characterizing the structural dynamics of biomolecules and investigating the contributions such dynamics make to biomolecular function; drafting and editing grant proposals, progress reports, and manuscripts; mentoring postdoctoral-, graduate-, and undergraduate researchers. Minimum Degree Required: Ph.D. Minimum Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biophysics, Biological Sciences, Molecular Biology, or similar; minimum of completion of Ph.D. studies and expertise in the purification and labeling of proteins, biochemistry, molecular biophysics, single-molecule biophysics, and/or fluorescence microscopy. The qualified candidate will have a foundation in thermodynamics and its application to nucleic acids and proteins, as well as, a foundation in chemical kinetics and its application to biomolecular binding and folding Preferred Qualifications: 2-5 years of research experience after completing a Ph.D. for Associate Research Scientist candidates. 6-8 years of research experience after completing a Ph.D. for Research Scientist candidates Experience working with ribosomes, RNA, and/or membrane proteins; expertise in single-molecule biophysics and/or fluorescence microscopy; proficiency at building, optimizing, and/or maintaining laboratory-built fluorescence microscopes, particularly total internal reflection fluorescence (TIRF) microscopes; excellent analytical skills; experience using/writing data analysis scripts in common programs such as Python or MATLAB; strong writing skills; experience in writing grants and scientific research articles; the ability to work independently as well as collaboratively. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

PhD degree in Computational Biology, Computer Science, Chemistry, Physics or related disciplines, with up to 2 years of industry research experience (Scientist) or 2+ years of industry research experience (Senior Scientist). We are looking for exceptional machine learning scientists who want to perf

The Lamont-Doherty Earth Observatory of Columbia University invites applications for an Open-Rank Associate Research Scientist (ARS) or Research Scientist (RS) to provide support to the Science Program Officer for the United States Scientific Ocean Drilling Coordination Office (SODCO). The ARS or RS will serve as the SODCO Science Program Officer by providing scientific and programmatic input in establishing the SODCO at LDEO. Works with other Principal Investigators (PIs) at LDEO and externally in developing and implementing research projects, collecting and analyzing data, and engaging in outreach initiatives. Will function independently and exercise a high level of expertise. Will receive guidance and direction from, and reports to, the Research Scientist at LDEO serving as the SODCO Director of Science Services and/or the Associate Director of Marine and Large Programs, if needed. Characteristics and Responsibilities: • Assists the Research Scientist serving as the SODCO Director of Science Services in establishing the SODCO at LDEO by providing scientific and programmatic support, particularly regarding science planning activities and science communications., • Prepares reports, writes documentation, and makes presentations concerned with SODCO and U.S. scientific ocean drilling and related programs, as requested by SODCO or other LDEO Principal Investigators., • Coordinates with Research Scientist serving as SODCO Director of Science Services and the Science Communications Manager on development and implementation of SODCO communications strategies and activities, including SODCO's public-facing website and social media platforms., • Supports PIs in special projects to acquire, analyze, and interpret scientific and engineering data. Provides documentation of analysis and project results., • Pursues and carries out independent research efforts within overarching goals set by PIs., • Other activities, as requested by SODCO Directors., • Received guidance and direction from, and reports to, the Research Scientist serving as SODCO Director of Science Services and/or the Associate Director, MLP, if needed. Functions independently within general guidelines and assumes project management responsibilities, as requested. Provides assistance/training for proposal PIs, seagoing scientists/staff, and visiting via online and in-person meetings. Non-routine physical activities limited to field assignments., • Assists in monitoring and prioritizing research-related expenditures within a budget of approximately $1,000,000 per year. The successful candidate should have a Ph.D. in Earth science. Rank will be commensurate with experience (at least two years for ARS; at least four years for RS). Excellent communication, organizational, and writing skills in English are needed. Seagoing experience and a solid record of scientific publications are preferred. Familiarity with scientific ocean drilling and/or large scientific programs is desirable but not required. The appointment is renewable annually upon successful performance evalution and availability of funding. Promotion in the Research Scientist track will be possible, based on experience and performance. The search will remain open for at least 30 days after the ad appears and will continue until the position is filled. Columbia University benefits accompany this Officer of Research appointment. This candidate should have a Ph.D. in Earth science. Rank will be commensurate with experience (at least two years for ARS; at least four years for RS). Excellent communication, organizational, and writing skills in English are needed. Seagoing experience and a solid record of scientific publication are preferred. Familiarity with scientific ocean drilling and/or large scientific programs is desirable but not required. Appointment renewable annually upon successful performance evaluation and availability of funding. Promotion in the research scientist track will be possible, based on experience and performance. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Opportunity This opportunity to join the Department of Pediatrics at the Vagelos College of Physicians and Surgeons at the rank of Associate Research Scientist with the Division of Cardiology is an exciting one. Columbia University Irving Medical Center, one of the nation's foremost academic health science centers. The Department of Pediatrics at Columbia University Irving Medical Center is the top in comparison with other pediatrics department in the NY region in NIH research funding. The primary focus of the Targoff Lab is to investigate the molecular and cellular mechanisms underlying cardiovascular development and regeneration. We accomplish these goals through the use of zebrafish as a model system and expand our studies into the fields of transcriptional regulation, cardiac mechanobiology, and stem cell biology. We utilize an innovative combination of genetic, live-imaging, single cell genomic, and transgenic approaches. We seek an energetic and inquisitive scientist who will work in a highly collaborative environment and who demonstrates critical thinking and academic rigor. Outstanding and exceedingly motivated candidates with backgrounds in developmental biology, genetics, and molecular biology. Key Responsibilities • Perform molecular biological experiments., • Perform confocal imaging., • Perform transcripomic anaylsis., • Carry out fully planned experiments., • Manage animal colonies (zebrafish husbandry) and performing animal work., • Interpretation of data and keeping records of results., • Contribute to the preparation of reports and publications., • Participation in seminars, conferences, lab meetings, and grant writing. Columbia University is an Equal Opportunity/Affirmative Action Employer and Educator. The University is dedicated to the goal of building a culturally diverse and pluralistic faculty and staff committed to teaching and working in a diverse environment, and strongly encourages applications from women, minorities, individuals with disabilities, and veterans. Columbia University welcomes applications from individuals who may have had nontraditional career paths, or who may have taken time off for family reasons (e.g. children, caring for disabled or elderly family), or who have achieved excellence in careers outside of academia (e.g., in professional or industry service). The University is responsive to the needs of dual career couples and is committed to supporting the work-life balance of its faculty. We are interested in candidates who have a record of success advising and mentoring individuals from groups underrepresented in higher education and is particularly interested in candidates who have research interests in subjects that will contribute to the understanding of diversity and equal opportunity. • PhD in Epidemiology or Biostatistics or relevant area, • 2-3 years of postdoctoral training required (applicable only for rank of Associate Research Scientist), • Consistently strong interpersonal skills and the ability to build and sustain effective working relationships with professionals in other disciplines., • The ability to create a high-energy results-oriented work environment that encourages colleagues and staff to value each other's contributions. Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The College of Dental Medicine invites candidates to apply for a position as Postdoctoral Research Scientist in the Regenerative Engineering Laboratory under the direction of Dr. Chang H. Lee. The Regenerative Engineering Laboratory, directed by Dr. Chang H. Lee, is a part of the Center for Dental and Craniofacial Research (CDCR) in the College of Dental Medicine. CDCR contains over 4000-sq feet of space, including state-of-art research facilities, and serves as an inter-campus hub for interdisciplinary collaboration. The Lee Lab has a long-lasting, active collaboration with the Department of Orthopedic Surgery and the Department of Biomedical Engineering. The candidate will have an opportunity to investigate multi-tissue crosstalk and the effect of patient specific pathophysiological factors in joint tissue disease, injury and regeneration. Self-motivated individuals with PhD in Mechanical Engineering or Biomedical Engineering with Organ-On-a-Chip expertise are encouraged to apply. PhD with at least five years of wet lab research experience in a related field. Candidates should demonstrate excellent scientific vigor, critical thinking, written and oral communication skills, and the ability to work independently and collaboratively in a multidisciplinary team. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Lamont-Doherty Earth Observatory of Columbia University is seeking a Senior Staff Associate II to contrive, design, develop, optimize, and enhance complex data systems operated by the Lamont Goeinformatics Research Group (GRG). The SSAII will conduct research in a collaborative research environments to deliver innovative solutions for functions, capacity, interoperability, performance, and efficient maintenance of adademic Earth Sciences data systems and services; operate and improve existing software and database solutions. Provide formal guidance to junior team members. Collaborate with other team members and with external peers to build consensus. Must exercise creativity and/or expertise in the normal performance of duties. Present at conferences and seminars; participate in development of funding proposals, manuscripts, and other research-oriented documentation. Duties and Responsibilities include: • Contrive, design, develop, and optimize complex cloud-based architecture for data infrastructure and web applications that manage and provide access to research data. Work from product requirements developed by GRG project and product managers based on user scenarios and as approved by PI., • Plan and execute development, deployment, and administration of back-end infrastructure and front-end applications in a DevOps environment, working as part of the GRG Technical Team. Provide formal guidance to junior team members., • Participate in the development of funding proposals and manuscripts; present at conferences and seminars., • Maintain documentation of development and operational procedures and frameworks as part of the GRG DevOps environment., • Will exercise independent judgement and initiative. Receives general supervision from the Doherty Senior Research Scientist. Bachelor's degree in Earth Sciences or Engineering and 10 years of relevant experience in the development of scientific geoscience data systems. Proven track record of working with cloud-based architecture, particularly AWS (Amazon Web Services). Advanced knowledge of data modeling semantic web and database design, proficiency with SQL and NoSQL databases technologies. Knowledge and experience of programming languages such as Java, JaveScript, Python, PHP, etc. Knowledge and experience with web frameworks such as Angular, Next.js, Node.js, Django, Express.js, Spring. Knowledge and experience with API development skills. Knowledge and experience with container technologies, DevOps and CI/CD, Git/Version control. Familiarity with current trends in geoscience research and data system development. Strong analytical and problem-solving skills. Highly organized and efficient, excellent oral and written communication skills. Knowledge and experience with GIS system such as GeoServer, ArcGis. The search will remain open for at least 30 days after the ad appears and will remain open until the position is filled. Appointments are made on a fiscal year basis and are eligible for renewal each July 1, contingent upon performance and funding. Columbia University benefits accompany this Officer of Research appointment. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Opportunity This opportunity to join the Department of Pediatrics at the Vagelos College of Physicians and Surgeons at the rank of Associate Research Scientist is an exciting one. Columbia University Irving Medical Center, one of the nation's foremost academic health science centers. The Department of Pediatrics at Columbia University Irving Medical Center is the top in comparison with other pediatrics department in the NY region in NIH research funding. The Division of Molecular Genetics at Columbia University Irving Medical Center in New York City is seeking a highly motivated Associate Research Scientist to immediately participate in the conduct of studies on the molecular and cellular mechanisms of Prader-Willi syndrome, using stem cell models of human disease. The applicant will be using various techniques including the genetic modification of stem cells, directed differentiation, flow cytometry, immunocytochemistry, single molecule analysis of replicating DNA, and whole genome copy number analysis. Key Responsibilities The successful candidate will be working on studies using both cells from patients with Prader-Willi syndrome and from healthy controls to study the molecular mechanisms of the differential progression of DNA replication on maternal and paternal alleles at the Prader-Willi locus. S/He will be working on project: "Causes and Consequences of DNA Replication Stress in the Mammalian Preimplantation Embryo" and preparation, submission and revision of the manuscripts for publication. S/He will be using various techniques including the genetic modification of stem cells, directed differentiation, flow cytometry, immunocytochemistry, single molecule analysis of replicating DNA, Atac-seq and whole genome copy number analysis. S/He will participate in team collaborative research team meeting and conferences, seek input actively and develop strong communication skills, and other activities related to the research program of the PI's lab. Commintment of Diversity Columbia University is an Equal Opportunity/Affirmative Action Employer and Educator. The University is dedicated to the goal of building a culturally diverse and pluralistic faculty and staff committed to teaching and working in a diverse environment, and strongly encourages applications from women, minorities, individuals with disabilities, and veterans. Columbia University welcomes applications from individuals who may have had nontraditional career paths, or who may have taken time off for family reasons (e.g. children, caring for disabled or elderly family), or who have achieved excellence in careers outside of academia (e.g., in professional or industry service). The University is responsive to the needs of dual career couples and is committed to supporting the work-life balance of its faculty. We are interested in candidates who have a record of success advising and mentoring individuals from groups underrepresented in higher education and is particularly interested in candidates who have research interests in subjects that will contribute to the understanding of diversity and equal opportunity. Professional Experience/Qualifications • Must have a doctorate degree (M.D. or Ph.D.) in Physiology with animal and stem cell experience., • Excellent oral and written communication skills, advanced organizational skills, a strong work ethic, and the motivation to identify scientific problems and solve them. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Department of Applied Physics and Applied Mathematics at Columbia University invites applications for an Associate Research Scientist position in theoretical condensed matter and materials physics, with an emphasis on the development of computational and analytical methods for strongly correlated electron systems. This position is part of a research program dedicated to advancing the Variational Discrete Action Theory (VDAT) - a novel variational approach to the quantum many-body problem. Candidates should have a strong background in theoretical/computational condensed matter and or materials physics, or related field. Experience with computational many-body physics is desired, including techniques such as the dynamical mean-field theory, quantum Monte-Carlo approaches, diagonalization approaches, etc. Strong candidates with related, but different, expertise will be considered. Programming experience is desirable. Strong communication skills (oral and written) are essential, and the ability to mentor students in a team environment is desirable. The position is initially for six months, possibly extending to four years. The position is available immediately and will remain open until it is filled. T Candidates must have a PhD in physics, materials science, applied math, chemistry, or a related field with a minimum of 2 years of relevant post-PhD experience. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Oppurtunity This opportunity to join the Department of Pediatrics at the Vagelos College of Physicians and Surgeons at the rank of Postdoctoral Research Scientist is an exciting one. Columbia University Irving Medical Center, one of the nation's foremost academic health science centers. The Department of Pediatrics at Columbia University Irving Medical Center is the top in comparison with other pediatrics department in the NY region in NIH research funding. The primary responsibility of this role is the characterization and validation of chemical compounds identified from throughput screens ongoing for a group of genetic disorders known as lysosomal storage diseases affecting the central nervous system (e.g. metachromatic leukodystrophy and Krabbe disease). The Postdoctoral Research Scientist will work on examining analogs synthesized from "hits" from two innovative cell-based and biochemical assays, using imaging and tandem mass spectrometry approaches. The successful candidate will have completed a PhD and/or MD and have experience in the following areas: Key Responsibilities • Basic molecular biology techniques include but are not limited to, molecular cloning, transfection, infection, RNA isolation, and Northern blotting., • Perform and develop lipids and sphingolipids extraction methods from diverse matrices, with the goal of identifying novel surrogate disease markers through tandem mass spectrometry., • Perform animal (mouse) experimentation, including general husbandry care, organization of murine colonies, breeding, neurobehavioral assessments with specific instrumentation, surgeries, periodic small molecule administration at different routes, general health assessments, postmortem perfusion, organ/tissue dissection, and other animal procedures., • Perform tissue cryosection and immunofluorescence staining procedures for confocal microscopy and MALDI-TOF and electron microscopy studies., • Familiar with concepts of parametric and non-parametric statistics, GraphPad, Excel, PubChem, PDB, ImageJ, AxoSeg, Volocity, and ZEN 2009 edition., • Present and write peer-review articles and progress reports and prepare presentations as oral or poster in scientific meetings. Columbia University is an Equal Opportunity/Affirmative Action Employer and Educator. The University is dedicated to the goal of building a culturally diverse and pluralistic faculty and staff committed to teaching and working in a diverse environment, and strongly encourages applications from women, minorities, individuals with disabilities, and veterans. Columbia University welcomes applications from individuals who may have had nontraditional career paths, or who may have taken time off for family reasons (e.g. children, caring for disabled or elderly family), or who have achieved excellence in careers outside of academia (e.g., in professional or industry service). The University is responsive to the needs of dual career couples and is committed to supporting the work-life balance of its faculty. We are interested in candidates who have a record of success advising and mentoring individuals from groups underrepresented in higher education and is particularly interested in candidates who have research interests in subjects that will contribute to the understanding of diversity and equal opportunity. • Must have a doctorate degree (M.D. or Ph.D.), • Consistently strong interpersonal skills and the ability to build and sustain effective working relationships with professionals in other disciplines., • The ability to create a high-energy results-oriented work environment that encourages colleagues and staff to value each other's contributions. Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Department of Applied Physics and Applied Mathematics (APAM) at Columbia University in the City of New York invites applications for Associate Research Scientist positions in the area of magnetically confined plasma research. There are up to 4 positions under consideration. The successful candidate will advance research in magnetically confined plasmas and support the broader goals of the Columbia Fusion Research Center. In the tokamak area, the candidate may conduct research on experimental tokamak facilities in the public sector. Examples include the DIII-D tokamak located at General Atomics or the National Spherical Torus Experiment Upgrade located at Princeton Plasma Physics Laboratory, or tokamaks located abroad. In the stellarator area, the candidate may conduct research in coil optimization, energetic particle physics, and other related activities. Activities may also be conducted in support of industrially sponsored research contracts originating from a wide array of sponsors, including concepts beyond tokamaks and stellarators. The successful candidate will also be expected to assist in the mentorship of more junior scientists, post-doctoral researchers, and students. In addition, the candidate is expected to conduct both supporting and independent research towards the execution of the Columbia Fusion Research Center research program, likely supporting multiple research awards. Candidates for professional officer of research positions are expected to have established their ability to conduct original, independent scientist research. To the rank of an associate research scientist, candidate's qualifications and contributions to their fields of research must be equivalent to those of an assistant professor. All candidates for all officer of research positions are expected to be able to work well in a team and to communicate effectively the results of their research or research activities both orally and in writing. The level of appointment is commensurate with experience. The earliest position is expected to begin on approximately Jan 1st 2026 or sooner if possible, with possible additional positions being filled later in 2026. The search will close no sooner than December 1st 2025 and will remain open until the positions are filled. Columbia University is an Affirmative Action/Equal Opportunity Employer. Minimum Qualifications: Ph.D. (or equivalent professional degree) in plasma physics or a related field, and experience with different computer environments and languages especially Python, Matlab, IDL, FORTRAN and UNIX/LINX. Candidates for professional officer of research positions are expected to have established their ability to conduct original, independent scientist research. To the rank of an associate research scientist, candidate's qualifications and contributions to their fields of research must be equivalent to those of an assistant professor. All candidates for all officer of research positions are expected to be able to work well in a team and to communicate effectively the results of their research or research activities both orally and in writing. Preferred Qualifications: Familiarity of working with magnetically confined plasma computational modeling tools and their application to interpret experimental or simulated data. Familiarity with magnetically confined plasma experimental data and measurement methods. Demonstrated track record of mentorship of junior scientists, post-doctoral fellows, or students. Publications in top-rated journals in the field and presentations at national and international conferences. Candidates should be open to relocation to the New York City area. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Irving Institute for Cancer Dynamics invites applications for a postdoctoral researcher position to join the theoretical immunology group led by Dr. Rane. The postdoctoral fellow will work directly with Dr. Rane on investigating the dynamics of the immune system in both health and disease. Funds are available for conference travel and professional development. The initial appointment will be for one year and is full-time and benefitted, with potential for renewal for a second year, pending annual review of performance and continued availability of funding. Duties & Responsibilities: • Successful candidates will develop and refine computational, mathematical, and statistical models to understand and explain biological phenomena., • Create algorithms to integrate large and diverse datasets into theoretical frameworks for modeling complex biological systems., • Collaborate closely with leading experts in the fields of experimental immunology and computational biology., • Contribute to the generation of impactful research findings in applied math, statistics, and immunology, with potential applications to areas such as cancer research, cell biology, and ecology., • Present research at meetings and write manuscripts and grants., • Ph.D. in applied mathematics, data science, statistics, computational biology, or a related field., • Proficiency in one or more programming languages, including but not limited to Python, R, C++, Stan, etc., • Excellent written and oral communication skills., • A demonstrated interest in immunology, cancer research, cell biology, or ecology is advantageous, though not mandatory. Minimum Requirements: • Ph.D. in a relevant field., • Programming proficiency., • Ph.D. in applied mathematics, bioinformatics, or computer science, plus prior experience applying these skills to biology or related fields., • Publications that demonstrate expertise in areas related to this project., • Immunology knowledge or the willingness to learn it quickly. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Columbia Nano Initiative (CNI) seeks an outstanding candidate to fill one opening for the position of Senior Director of the CNI Labs at the rank of Research Scientist. Reporting to the Scientific Director of the Columbia Nano Initiative (CNI), the Research Scientist will actively participate in multidisciplinary CNI research programs in close collaboration with CNI-affiliated faculty and researchers. The Director of CNI Shared Laboratory Facilities, which include the cleanroom, electron microscopy facilities, the shared materials characterization facilities, and any newly developed facilities as needed will assist principal investigators (PIs) in their research and utilization of shared facilities and equipment, serving as a key strategic partner and subject-matter expert in equipment operation, configuration, capabilities, and maintenance to ensure high-quality research outcomes. The Research Scientist will provide guidance and expertise in various aspects of laboratories operation. Additionally, they will be responsible for the operational and financial management of the laboratories, collaborating closely with the Shared Facilities Committee and the CNI Executive Committee to ensure safe and effective operations, maintain necessary IT systems, and comply with all university and government regulations. The Research Scientist will also oversee modifications to available space as needed for new equipment, working with Columbia Facilities staff and contractors. They will ensure a safe laboratory environment and foster collaboration with Columbia University's Environmental Health & Safety (EH&S) office. Additionally, the Research Scientist will continue to develop and lead external user programs, oversee lab budgets, and facilitate lab operation costs through user fees in collaboration with the CNI finance office. They will also maintain long-term plans for equipment, maintenance, and staffing and contribute to grant applications for new equipment and large center grant proposals. The Research Scientist may also collaborate on research activities within the Columbia Nano Initiative, particularly those requiring specialized expertise in the Shared Laboratory Facilities. She/he may also lead proposal development efforts and serve as PI or Co-PI on proposals as needed. Key Responsibilities Research Collaboration • Actively collaborates on multidisciplinary research programs involving CNI-affiliated faculty and researchers from the Departments of Chemistry, Physics, Applied Physics, Electrical Engineering, Chemical Engineering, and Mechanical Engineering, as well as faculty and researchers at affiliated institutions. She/he should also possess the ability to foster interdisciplinary research, manage internal and external research relationships, and to participate in the mentorship of junior scientists., • Serves as a subject-matter expert in the operation, configuration, capabilities, and maintenance of CNI Shared Laboratory equipment and assists in interpreting experimental results., • Ensures high-quality scientific outcomes for research activities in the Shared Facilities., • Ensures safe operation and full compliance with university and regulatory policies for all CNI facilities., • Trains laboratory users in safe and effective equipment operation., • Serves as a key strategic partner for PIs and researchers in designing and implementing experiments utilizing Shared Laboratory equipment., • Proactively collaborates with faculty to develop proposals for facility development and expansion., • Assists colleagues in preparing grant proposals for new and continuing research programs., • Provides operational leadership for the Shared Laboratory Facilities, ensuring the proper functioning of all equipment through routine maintenance and necessary repairs., • Manages and optimizes space utilization in collaboration with the CNI Director of Finance and Administration., • Develops and maintains laboratory management programs for logging and controlling instrument access while ensuring accurate charge-back and billing information., • Maintains laboratory communications, including website updates., • Ensures the creation and ongoing updates of standard operating procedures (SOPs) for all facilities., • Monitors overall budgets and manages expenses for the Shared Laboratory Facilities., • Oversees charge-back accounts and provides annual and interim reports to CNI leadership., • Negotiates and monitors service contracts for CNI facilities., • Reports directly to the CNI Scientific Director. Qualifications A Ph.D. or its professional equivalent is required. Experience of at least five years of working in a cleanroom lab, and familiarity with materials characterization techniques and electron microscopy are also required. A minimum of three years of people management experience is necessary. For the rank of Research Scientist, the equivalency is with the qualifications and contributions of an Associate Professor Preferred Qualifications Ten or more years of extensive professional experience in laboratory management, including supervising interdisciplinary teams of scientists and engineers. We seek applicants with a strong background and leadership skills. Additional desired qualifications include: • Strong technical experience in conventional cleanroom processes used for electronic and mechanical device fabrication., • Understanding of new and modern laboratory-scale fabrication processes required for state-of-the-art fabrication, including thin film deposition, electron microscopy, electron beam lithography, nanoimprint lithography, and reactive ion etching., • Excellent interpersonal, managerial, and communication skills., • Excellent analytical reasoning and problem-solving skills., • Strong organizational skills., • Ability to work with frequent interruptions and minimal supervision., • Knowledge of safety and hazardous waste protocols., • Ability to exercise mature judgment and initiative., • Understanding of the operations and characteristics of physical plants and facilities. Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

Pos Position Summary The Division of Surgical Science at Columbia University Vagelos College of Physicians and Surgeons is accepting applications for an Associate Research Scientist. The individual will be responsible for performing basic and translational research in the area of gastroesophageal cancer research. The individual will work alongside the principal investigator in developing and performing scientific protocols, organizing and discussing results, as well as submitting scientific manuscripts and grants. The position involves conducting independent research, collaborating on multidisciplinary projects, and contributing to the development of innovative therapeutic strategies. Responsiblities • Design and execute experimental studies in gastroesophageal cancer focusing on the role of the tumor immune microenvironment, • Conduct in vivo experiments with genetically modified murine models and preclinical models of gastroesophageal cancer including mouse surgery and the generation of orthotopic models of gastroesophageal cancer, • Analyze and interpret data, ensuring the rigor and reproducibility of research findings., • Collaborate with interdisciplinary teams, including clinicians, translational scientists and basic scientists, • Contribute to the preparation of manuscripts, grant applications, and progress reports., • Supervise and mentor junior researchers, including postdoctoral fellows, graduate students, surgical residents, technicians and undergraduate studetns., • Present research findings at internal meetings, national and international conferences, and in peer-reviewed publications., • Maintain detailed and organized records of experimental procedures and data analysis in an Electronic Lab Notebook., • Stay current with advancements in gastroesophageal cancer translational research, incorporating new techniques and knowledge into ongoing projects., • Ensure compliance with all regulatory and safety protocols in the laboratory., • Assist in the development and optimization of in vivo and in vitro models of gastroesophageal cancer research MD o MD or PhD Preferred experience in: Experience in gastroesophageal cancer in vivo and in vitro models and assays Experience with mouse surgeries and generation of pre-clinical models of gastroesophageal cancer research Pre Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

We are inviting applications for a Postdoctoral Research Scientist position in applied mathematics and scientific computing, emphasizing inverse problems in seismology and Bayesian analysis. The position is associated with the Modeling Earth from Atomic to Global Scale (MINERALS) project funded by the Gordon and Betty Moore Foundation. The project aims to advance and integrate three branches of geophysics - mineral physics, seismology, and geodynamics - to analyze and interpret the seismological structure of the deep Earth. The successful candidate will work in a multidisciplinary team of senior and junior scientists to develop machine learning and Bayesian methods to interpret seismic tomographic models of the elastic structure of the deep Earth in terms of temperature and mineralogy. Using thermodynamic properties databases, these analytical methods will also be applied to predict equilibrium mineral assemblages in collaboration with an international team of geochemists and petrologists. The position is initially for one year, possibly extending to four years. The position is available immediately and will be open until the position is filled. Applicants should send a CV, three recommendation letters, and a cover letter containing a research statement summarizing the candidate's past experiences and future goals. Applications should be submitted through the Academic Search and Recruiting (ASR) system on the Columbia University portal. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Zeltser lab is looking for a motivated scientist to join their team as an Assistant Professor of Medical Sciences in Medicine at the Columbia University Medical Center (non-tenure track). The lab studies how the sympathetic nervous system regulates metabolism and how this is impacted by obesity and aging. We utilize a variety of genetically engineered mouse models, virus-based neural tracing and chemogenetic approaches, single nuclear transcriptomics, and in vivo physiological and metabolic measurements. The ultimate goal is to identify neural circuits that regulate distinct aspects of brown fat and function and systemic metabolism. The ideal applicant will be an experienced researcher with expertise in both neuroanatomy and the neurobiology of autonomic regulation of peripheral targets and/or central regulation of metabolic parameters. The procedures for this project require expertise in multiple advanced techniques. The experienced researcher must be able to master state-of-the-art techniques to map and manipulate sympathetic circuits regulating discrete targets in the periphery, including stereotaxic injections, viral tracing, chemogenetics and fiber photometry. In parallel, this project also involves the analysis of physiological phenotypes in vivo, including thermogenesis, glucose uptake and lipolysis. Experience with surgical techniques in mice is essential. The applicant will be expected to lead projects independently and to train and mentor others. The applicant is also expected to make substantive contributions to the formulation and writing of manuscripts and grant applications. Interest in developing new technologies is a plus. Responsibilities: • Perform daily lab activities to carry out research projects in the lab., • Perform basic neuroanatomical assays including mounting and immunohistochemical staining in sections, clearing and immunostaining in intact brains, and imaging using confocal and light sheet microscopy., • Perform physiological and metabolic assays in mice., • Perform surgeries in mice to inject compounds and to implant devices in the brain and the periphery., • Train and mentor others., • Contribute to the formulation of grant applications, primary research papers and review articles., • Minimum Qualifications: Applicants should have a PhD, MD or MD/PhD in Cellular Biology with at least 5 years of postdoctoral experience. Excellent oral and written communication skills, a strong work ethic, and the ability to work independently are essential. Well-versed with molecular biology and basic techniques to measure mRNA and protein. Proficient at performing complicated experiments in a timely manner. Ability to work independently and collaboratively. Willingness to work with mice. Technical accuracy, reliability, and attention to the details of procedural protocols, organizational skills, adherence to safety guidelines and the ability to work in a team. Excellent organizational skills and a strong interest in biological sciences. Preferred Qualifications: Experience in leading a group is preferred. Experience in mouse handling and colony maintenance highly preferred. Experience in basic histological procedures (i.e. immunohistochemistry and in situ hybridization) is preferred but not essential. Experience in mouse surgical procedures is preferred. Experience with R is preferred but not essential. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Department of Radiology at the Columbia University Vagelos College of Physicians and Surgeons invites applications for a Director of PET and Molecular Imaging Instrumentation. This leadership role is intended for a PhD-level scientist with deep expertise in molecular imaging and translational human imaging research. The Director of PET and Molecular Imaging Instrumentation will provide scientific vision and leadership for human PET and SPECT imaging research, with a strong emphasis on molecular imaging, theranostics, and first-in-human investigations. The successful candidate will play a central role in advancing innovation, integration, and collaborative research across the CUIMC enterprise. Program Highlights Columbia's Molecular Imaging Program features a world-class PET Center, including two cyclotrons supporting [13N], [15O] target production and dual-target capabilities for [11C] and [18F] isotopes. The program is equipped with three state-of-the-art PET scanners for both clinical and preclinical applications and has a robust infrastructure for isotope production, tracer development, and advanced imaging protocols. Strong industry partnerships provide exciting opportunities for innovation and collaboration in imaging sciences. Responsibilities The Director of PET/SPECT Imaging will be expected to: • Provide scientific and strategic leadership for PET and SPECT imaging research involving human subjects., • Develop, lead, and sustain an independent and/or collaborative research program in molecular imaging, theranostics, or related translational imaging sciences., • Oversee and advance first-in-human and early-phase clinical imaging studies, including novel radiotracers and imaging methodologies., • Collaborate closely with radiochemistry, medical physics, and clinical teams to translate novel imaging agents and technologies from preclinical development to human application., • Define and implement a strategic vision for PET/SPECT imaging innovation, including quantitative imaging, dosimetry, image reconstruction, and multimodality integration (PET/CT, PET/MR, SPECT/CT)., • Collaboratively support PET/SPECT research operations, including protocol development, scanner utilization, and optimization of imaging performance., • Contribute to regulatory and compliance activities related to human imaging research (e.g., IRB, IND/IDE, radiation safety), in partnership with departmental and institutional offices., • Establish and strengthen collaborations across CUIMC, including with the Herbert Irving Comprehensive Cancer Center, Biomedical Engineering, Biomedical Informatics, Neurology, Radiation Oncology, and the Irving Institute for Clinical and Translational Research., • Promote partnerships with industry, funding agencies, and external academic institutions to accelerate innovation and translation. * Publish high-impact, peer-reviewed research and present findings at national and international scientific meetings., • Teach and mentor graduate students, postdoctoral fellows, residents, and junior faculty, contributing to the department's educational mission Qualifications Required • PhD in Medical Physics, Biomedical Engineering, Radiological Sciences, Chemistry, Physics, or a closely related field., • Demonstrated expertise in PET and/or SPECT imaging, molecular imaging science, and quantitative imaging methodologies., • Strong record of peer-reviewed publications., • Experience conducting or supporting human imaging research., • Demonstrated ability to work collaboratively in a multidisciplinary academic environment. Preferred, • Experience in theranostics, radiopharmaceutical development, or translational molecular imaging., • Track record of extramural research funding as Principal Investigator or key collaborator., • Prior leadership or program development experience in an academic imaging environment., • Familiarity with regulatory pathways for human imaging studies (IRB, IND/IDE, radiation safety). Salary Salary range is $430,000 - $550,000. Columbia offers a generous benefits package. Salary will be commensurate with experience and qualifications. Columbia University offers a highly competitive benefits package. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

Associate Research Scientist position available immediately in a leading laboratory investigating host-pathogen interactions. Self-motivated individuals with PhD degree or equivalent with a strong background in one or more areas of immunology, microbiology, cell and molecular biology, and cancer biology are encouraged to apply. PhD with at least five years of wet lab research experience. Candidates should have excellent publication records and demonstrate excellent scientific vigor and integrity, critical thinking, written and oral communication skills and ability to work independently as well as collaboratively in a multidisciplinary team. Experience with rodents is required. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

We are inviting applications for an Associate Research Scientist position in energy storage, emphasizing advanced lithium metal battery technology. The project aims to develop high-performance electrolytes and anodes for lithium metal batteries. The successful candidate will work in a multidisciplinary team of senior and junior scientists in materials science. The position is available immediately and will remain open until it is filled. Applicants should send a CV and a list of reference, and a cover letter summarizing the candidate's past experiences and future goals. Applications should be submitted through the Academic Search and Recruiting (ASR) system on the Columbia University portal. Candidates must have a PhD in materials science, chemistry, chemical engineering and relevant disciplines. Experience in battery chemistry and manufacturing is preferred, but not required. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The Vagelos College of Physicians and Surgeons (VP&S) is seeking a new Director of the Center for Radiation Research (CRR). This key leadership role will oversee and drive the development, implementation and management of radiation research initiatives within VP&S, as well as in the Department of Radiation Oncology, where it will be administratively based. The Center will serve as the translational "bench' research hub for the Department and the Director will report to the Department Chair. The Center Director will play an important role in VP&S scientific leadership, participating in the VP&S Scientific Council of Center and Institute Directors, the Herbert Irving Cancer Center leadership team, and in key University programmatic initiatives. The successful candidate will be expected to be a world-class radiation scientist with a history of pioneering research accomplishments, leadership experience and a proven track record in identifying outstanding young researchers and fostering their careers. The Center is located at two campuses - CUIMC and at the Columbia University Nevis Laboratories in Westchester County. The latter houses the CRR's Radiation Research Accelerator Facility (RARAF, ___), the only accelerator facility in the United States dedicated to the pre-clinical study of the biologic effects of ionizing radiation. Major programs include pre-clinical research into heavy-ion charged particle and FLASH radiotherapy; understanding the biological effects of very low doses of radiation including radiation risks associated with CT scans, space radiation and nuclear power/events, and a new research portfolio leveraging far ultraviolet (far-UVC) light as a tool to control the spread of airborne-mediated microbial diseases. Candidates who are leaders in these or other areas of radiation biology, including DNA repair, radiation radiosensitizers and radio-immune modulation, are strongly encouraged to apply. The CRR currently has a total staff of 41, including 10 PhD faculty, 3 of whom are tenured, and has been internationally recognized as the premier radiation research program. Strategic Leadership: Provide strategic direction and leadership for the radiation research program, aligning objectives with the Department and institutional goals and priorities. Research Oversight: Oversee all aspects of radiation research activities including project planning, execution and evaluation in close collaboration with the Department Chair. Research Management: Manage human, financial and physical resources effectively to support the success of radiation research endeavors in collaboration with the Department Administrator and Chair. Collaboration: Foster collaboration and partnerships with internal and external stakeholders including faculty, researchers, clinicians, industry partners and funding agencies. Faculty Support: Provide mentorship and support to faculty members engaged in radiation research, facilitating their professional growth and development. Grant Writing: Assist faculty members in identifying funding opportunities and preparing grant proposals to secure external research funding. Regulatory Compliance: Ensure compliance with all relevant regulatory requirements, ethical standards and institutional policies governing radiation research. Education and Training: Contribute to the education and training of students, residents, fellows and other trainees in radiation research methodologies and practices. Quality Assurance: Implement quality assurance measures to uphold the integrity, accuracy and validity of radiation research findings. Communication: Serve as a spokesperson for the radiation research program, promoting its achievements and impact through publications, presentations and other communication channels. Applicants should have a PhD, MD, MD/PhD or equivalent degree, substantial national and international stature and expertise in managing large-scale research programs. The candidate is expected to provide leadership for the Center for Radiation Research in the Department of Radiation Oncology and articulate a vision for its continued growth, supported with a firm commitment to the recruitment of multiple new faculty members and facilities to match the recruitments. • Distinguished record of scholarly achievements, including a significant publication record in leading scientific journals and a demonstrated ability to secure external research funding., • Demonstrated international leadership in the field of radiation sciences through organization of conferences and serving on funding and award committees., • Demonstrated expertise in radiation sciences and research methodologies., • Proven leadership experience in academic or research settings., • Strong interpersonal, communication and collaboration skills., • Track record of securing research funding and publishing in peer-reviewed journals., • Knowledge of regulatory requirements and ethical considerations in research., • Leadership experience in academic or research settings with a proven track record of fostering collaboration and promoting excellence., • Strong commitment to graduate and/or medical education including a record of effective teaching and mentorship. Experience in mentorship of junior scientists and mid-career scientists will be considered as a plus., • Excellent communication and interpersonal skills with the ability to engage effectively with diverse stakeholders. Columbia University is an Equal Opportunity Employer / Disability / Veteran Pay Transparency Disclosure The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

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