D&d jobs in CheltenhamCreate job alerts

CLOUD ARCHITECT- Permanent opportunity for a Cloud Architect with active enhanced DV clearance.Salary up to £115,000 DOE + DV Bonus - Cheltenham based offices - To apply, please call Laura Jackson on , or email with an up-to-date CV.WHO ARE WE?We're hiring for Cloud Native Architects to join a cons

Up to £65,000 depending on experience and clearance.Lead cybersecurity operations and strategy within a growing technical environment.Must hold active, or be eligible for, SC clearance.Opportunity to shape policies, manage risk, and guide a dedicated cyber team.Our client is a technology focused or

Key Responsibilities * Maintaining rooms and communal areas to exceptional standards * Conservation-grade dusting and careful handling of valuable and delicate items * Comprehensive laundry care, including fine fabrics * Room refreshes and turndown services * Assisting with informal d

HGV Technician Mobile, Merseyside.Working Hours: Monday - Friday, 07.Carry out on-site servicing and repairs using comprehensive system specialist knowledge and a high diagnostic authority.To attend customer locations daily and manage your efficiently between sites, reacting to urgent and reported d

We are working with a very technical SME client who is actively seeking 2 Infrastructure Engineers to join their team, one at Senior level & one at Lead. They operate within the highly technical fields of cyber technologies and software assurance, with a specific focus on safeguarding national i

Senior & Lead (2 positions). Senior (Eligible for DV), Lead (Actively DV Cleared). We are working with a very technical SME client who is actively seeking 2 Infrastructure Engineers to join their team, one at Senior level & one at Lead.

Senior Mechanical Design Engineer.Join a leading R&D team as a.Senior Mechanical Design Engineer.DFM, DFMEA) to develop innovative, high-performance machinery solutions.Youll be responsible for producing complete manufacturing packages (Machinery) for mechanical System Elements including general

Are you someone who finds joy in helping others live life to the fullest?.She lives with complex health needs and uses a wheelchair, but her life is filled with creativity, laughter, and connection.Provide warm, person-centred care and emotional support.Encourage independence and wellbeing through d

Redline has been retained by a leading process instrumentation manufacturer who are looking for a Engineering Manager to join their R&D team based in Surrey.Due to significant growth, they are seeking an Electronics Team Leader to be responsible for engineering and R&D for highly regulated p

PRINCIPAL DEVOPS ENGINEER- Permanent opportunity for a Lead/ Principal DevOps Engineer with active enhanced DV clearance. PRINCIPAL DEVOPS ENGINEER ESSENTIAL SKILLS- Strong experience operating in an SRE/ DevOps environment - Expertise in containerisation technologies such at Docker or Kubernetes, f

Garden centre experience, specifically within plant area manager experience. It's a tight-knit operation, very hands-on, and a real labour-of-love project, making this role perfect for someone who's passionate about their plants and a strong retail manager. Work closely with the Centre Manager and d

We're looking for a Learning & Development Partner to join our Laser HR team and play a pivotal role in shaping the future of talent across our business. Reporting into the Head of HR for Laser, you'll lead the strategy, design, and delivery of L&D initiatives, with a strong focus on our Ear

Main Responsibilities of the Senior Mechanical Design Engineer based in Lincoln, UK:. Senior Mechanical Design Engineer. An excellent opportunity for an experienced Senior Mechanical Design Engineer to join a global RF technology group as part of a specialist R&D team in the UK.

Scientist - Infectious Diseases - Oxford Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industrys most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.The primary purpose of this role is to contribute to cross functional efforts focused on applying the ImmTAX® platform or other modalities to the development of novel treatments for chronic infections, including HIV and HBV and EBV-associated diseases. The team is involved in multiple stages of the drug discovery and development process, from target discovery all the way to clinical trials. Examples of key preclinical research are published in Yang H et al., Mol Ther. 2016; 24,11; Fergusson J et al., Hepatology 2020; 72,5; Wallace Z et al., Mol Ther 2024; 32, 678.The postholder will plan, design and execute experimental investigations to support the advancement of the Company pipeline, processes and technology capabilities, with guidance from their manager, ensuring that project goals are met within time and budget constraints. They will be expected to demonstrate technical proficiency, rigour in assessing their own data and that of others, scientific creativity and independent thought. This position requires participation and presentation of results at internal meetings, sharing information learned at external scientific meetings and establishing productive relationships with colleagues across Research and other departments.Key Responsibilities: * With instruction and guidance from manager - plan, design, and execute assignments to meet project goals within defined timeframes* Execute experiments to address key scientific questions and enable project progression, utilizing range of molecular and cellular techniques including some of the following: NextGen sequencing, DD-PCR, qPCR, cell culture, flow cytometry, ELISpots, ELISAs,* Some work will be conducted in a containment level 3 (CL3 facility) and will require handling of human viruses* Analyse data, interpret results, and make recommendations* Proactively expand scientific/technical knowledge in relevant fields including HIV/HBV/EBV related disease biology and drug development through review of scientific literature/ conference updates, peer to peer mentoring, and attendance at seminars/conferences in line with company strategy* Work effectively in a matrixed team structure and as part of cross functional teams * Participate and present results at internal meetings* Establish relationships and possible collaborations within and outside of the companyEducation, Experience and Knowledge: Essential Qualifications: * PhD in molecular biology, cell biology, genomics, virology, immunology, or related discipline and 0-2 years related experience* Alternatively, a BSc or MSc with significant work experience in relevant scientific areas * Worked in a bench-based laboratory environment and proficient inthe following key techniques:o molecular techniques including some of the following: Droplet Digital PCR, NextGen sequencing, Genomics/Transcriptomics, PCR, Mutagenesis, qPCRo Culturing primary cells and/or cell linesPreferred Qualifications: * Knowledge/expertise of Immunology/HIV/HBV/EBV* Flow cytometry, ELISAs, ELISpots * Viral integration site analysis

Senior Scientist I - Characterisation | CMC - Oxford Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industrys most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.To characterise the companies biotherapeutic recombinant T-cell receptor based and related molecules using a wide variety of protein characterisation and mass spectrometry methods. To contribute to the development of characterisation methods for the companys biopharmaceutical products, including peptide mapping (LC-MS/MS) and intact mass spectrometry analysis. KEY RESPONSIBILITIES* Supporting drug substance and drug product impurity characterisation and identification* Performing protein sequence and post translational modification identification, including glycosylation analysis. * Supporting drug substance and drug product process development by performing characterisation of process intermediates * Contribute to the Development of characterisation methods of ImmTAX and other products, including peptide mapping (LC-MS/MS) and intact mass analysis * Designing and carrying out biochemical characterisation, chemical stability and comparability studies of biologics/drug products. * Contribute to writing study protocols and reports.* Independently testing and, increasingly, leading lines of investigation. Proposing new experiments based on emerging data and other related information. Providing support on technical aspects to others. * Priorities: establishing priorities for own work and team-based projects; making decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance. * Technical Knowledge: sharing knowledge with the wider team and, across departments representing the department. May also act as a mentor to other colleagues, sharing scientific knowledge. Providing analysis of new techniques and theories from outside the Company to advance the way the company works; sharing these with leaders across the department. * Laboratory records: ensuring that all records and information are up to date, on time and recorded to the correct standard. Supporting and encouraging others to achieve this.* Laboratory equipment: providing technical guidance to others within the team on how to use equipment most effectively.* Reporting: communicating and presenting research findings at meetings with colleagues, senior management and partners.* Adhere to safe working practices in laboratories according to Immunocore EHS policies.PERSON SPECIFICATIONExperience & knowledgeEssential* Experience in development of HPLC based peptide mapping methods and mass spectrometric characterisation of recombinant proteins or antibodies. * Experience of glycosylation analysis of recombinant proteins or antibodies.* Independently coordinated extensive testing of protein biomolecules.* Experienced in the characterisation of proteins expressed in both microbial and mammalian systems.* Understanding of expected post-translational modifications in biological systems.* Worked in a bench-based biopharmaceutical laboratory environment. * Established as an expert amongst peers in one or more of the following areas: o electrophoretic o chromatographic o mass spectrometry* Experienced in assay development * Familiar with biopharmaceutical stability study principles and interpretation thereof* Worked and contributed actively in a diverse team environment* Proposed and driven changes in working practices that have improved efficiency, supported teams through adoption and change* Presented detailed scientific findings and papers to internal and external audiencesDesirable * Experience of glycosylation analysis of recombinant proteins or antibodies* Experience with late stage/commercial biopharmaceutical assay development and characterisation * Familiar with the principles of Good Manufacturing Practise (GMP)* Presented at external conferences* Led a small project team, formally or informally, through a change in practice including project management * Understanding of analytical requirements to support materials for use in clinical trialsEducation & qualifications* Essential: BSc. Or MSc. in biochemistry, biotechnology or related discipline* Desirable: PhD in related discipline

For further information, call me on. Information Services, Government Administration, and Defense and Space Manufacturing.

A growing consultancy is seeking a Senior DevOps Engineer to enhance infrastructure for critical national security projects.Located in Bristol, Cheltenham, or Manchester, this role entails designing secure cloud infrastructures and managing Kubernetes clusters.Ideal candidates should have a robust D

DevOps Engineer / Cloud Consultant / DevOps Consultant / AWS / Azure / Kubernetes / CI/CD / Ansible / Terraform / Docker / Python / Cheltenham / Security Cleared / DV / DV Cleared / Enhanced Clearance.

Full-time Team Leader vacancy at GAIL's.If leading a team to success makes you smile and puts a spring in your step, then please read on!.We are looking for Team Leaders who have a passion to join the GAIL’s family and for supporting and.With no day being the same, you must be organised and.As app

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SEMH Chesham House school- Bury, Greater Manchester.Start date Easter 2026 / September 2026 for the right candidate.Are you a passionate and resilient leader ready to make a real difference?.Chesham House School is seeking an inspiring Assistant Headteacher to help lead our specialist SEMH pro

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Day shifts - 24 -36 hours per week 8am - 8pm (including every other weekend).Night Shifts - 36 hours per week 8pm - 8am (including every other weekend).Are you a naturally caring person and want to help make a difference in people’s lives? .If you are kind, compassionate and committed, w

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Wilt u deel uitmaken van Europa's toonaangevende premium gezondheids - en welzijnsgroep ?.Onze teamleden zijn de ambassadeurs van ons bedrijf en het hart van wat we doen.Wij zijn op zoek naar een gepassioneerde Sales Consultant om ons team te versterken !.Als Sales Consultant ben je 70% van je rol b

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Health Consultants Inc has over 30 years experience as a leading healthcare provider with international acclaim.We run 2 clinics in central London with Marylebone Physiotherapy & Sports Medicine being recognised as providing gold standard care for musculoskeletal disorders and incorporating the late

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Software Engineer - Edinburgh Company DescriptionA bit about usFounded and headquartered in Switzerland, Avaloq is continuously expanding its global footprint with around 2,500 colleagues in 12 countries, and more than 170 clients in 35 countries.We are an industry-leading provider of wealth manage

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Software Engineer - Onsite, Oxford.Our client is a pioneering company developing cutting-edge software platforms that enable process optimisation and automation in additive manufacturing and beyond.Design, develop, and maintain novel software platforms for:.Data management, traceability, visualisati

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По доходам среди всех мобильных приложений мы входим в топ-3 в мире, а в Европе мы первые.Наши игры установили 2,3 миллиарда раз (треть населения Земли), каждый день в н

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Aveni is redefining how financial institutions use AI.We build real, production-ready agentic systems that reshape how banks, advisers and financial services firms operate, replacing fragmented processes with intelligent, end-to-end workflows.We have been recognised as Fintech of the Year for two co

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Are you a junior engineer with a passion for Embedded Systems and C++?.Imagine having the opportunity to shape the future of a burgeoning RTOS company with your decisions.Are you eager to work with cutting-edge technology in the field of software development and embedded systems? Look no further!.As

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We are looking to hire a skilled Software Developer to join our dynamic and innovative team.As a Software Developer, you will be responsible for designing, implementing, and maintaining high-performance, scalable software solutions using Python and related technologies.You will collaborate closely w

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Low Latency C++ Engineer | Crypto Trading Powerhouse.Up to £185,000 DOE + RSUs + Bonus + Benefits.Fully Remote (must be based in the UK).Want to help shape the future of crypto trading?.This is a chance to join one of the world’s leading crypto trading platforms and a team known for its cutting-e

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CMS, Service Portal, Front-End Development, Quality & Testing.The Junior ServiceNow Developer will support the design, development, and testing of ServiceNow CMS and Service Portal solutions within a regulated retail environment.The role is delivery-focused, working under the guidance of senior deve

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The company are a multi-national group, being No 1 in Europe for what they do! With a number of awards and recognitions, with great career progression and opportunities across the business!.Are you a Software Engineer looking for your next challenge?.We have several exciting opportunities for Softwa

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Graduate OR mid-level Embedded C++ Software Engineer.West Sussex (BN postcode) – 4 days onsite per week.Must hold a valid driving licence (site is rural).As an Embedded Software Engineer, you will:.Develop embedded software in C/C++, with exposure to Rust, Python, and Linux environments.Work with

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