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Ramada Encore by Wyndham Newcastle-Gateshead is looking for a Sales Manager to join their team! SUMMARY The hotel sales manager is responsible for achieving/exceeding budgeted room revenue and function room rental targets as measured by calendar month, by quarter, and by year with measurement by budget, market share and annual growth percentage. The sales manager will have primary responsibility and ownership for key accommodation market segments (sales, production, account management) including: Market Segment TR Local Corporate TR Negotiated Global TR Government TR TMC GR Corporate GR CITY WIDE As well as for driving inclusive food & beverage packages including for groups & tours and SMERF groups in conjunction with the Hotel Reservations Manager to maximise total Departmental Revenue. Sales and Business Development activity must be achieved proactively in the main as well as reactively from enquiry and referral. This is a role where internal and as well as external activity, business development and client relationship building needs to have the personal touch (Face to face, telephonic and electronic) through managing a busy diary including hosting on site visits, visiting clients at their premises, establishing and maintaining positive meetings and contact with hotel business agents and travel management companies. This business activity will include booker familiarisation visits, in-house client entertainment on a regular basis as well as attending targeted North East regional business networking events. The Hotel Sales Manager will act as the essential link between client, booker, guest and the hotel to strengthen guest relations and develop hotel loyalty with the aim of driving revenue. Champion Wyndham Rewards to maximise Guest Loyalty and Benefit. The sales manager will be responsible for the creation, upkeep of the corporate trackers and all sales performance trackers in terms of uptake of booking volume, average rates and overall revenue. The sales manager will respond to all RFP (request for pricing) and quote for business, evaluating returns and business impact through Wish, Want, Walk process with discounting levels agreed by the Hotel Revenue Manager and GM. The sales manager will be the Hotel social media Champion – create, upload online content. The sales manager will create, contribute and present their Sales Activity, their success and the impact on hotel revenue at monthly and quarterly BRMS (Wyndham H&R / Ownership) ACTIVITY • Be an ambassador and sales winner for Ramada Encore Newcastle Gateshead to secure new business and guests to showcase the hotel at its best to win new business (B2B). Flexibility of working time and expressing hospitality to our regular and potential guests is a must-have for our sales manager as is professional and appropriate business attire and presentation (self and PPT etc), • Maintain the objective to ensure Guest Book Direct (analyse Booking,com and other bookings, promote Wyndham Rewards at every opportunity., • Maintain trackers to record and measure activity and success., • Plan and host client and guest site visits, entertainment, Familiarisation visits, show case events such as Quarterly Meet the Team., • Maintain an understanding of the hotel’s sales performance: Room Sales by occupancy, average room rate, occupancy and RevPAR: Actual versus budget, versus forecast and verses last year and other trends., • Always have a live and strategic plan to deliver budgeted rooms revenue and adapt fresh tactics to achieved the budgeted room sales using the 2026 Business Plan (Wynview) as the master plan with adaptions as the year progresses., • Plan and undertake a minimum of Six proactive and researched calls per working day to current, lapsed, targeted clients per week i.e. 24 logged calls per month – retaining outcomes., • Respond to all RFP (hotel and brand) within 24 hours of receipt by working closing with Hotel Revenue Manager and Reservations Manager in terms of meeting client need and for the hotel to achieve our RevPAR targets., • Keep shared business trackers, local corporate call logs on a password protected share drive., • Local area networking and local business membership and event attendance: Review, evaluate relevance, register and attend local area net working such as BNI, NE1 business breakfast, Mussel Club, Chamber of Commerce, Newcastle Gateshead Initiative etc., • Attend Client events and Tradeshows in the UK as well as regionally & locally – including evening, weekend and possibly overnight – reasonable expenses whilst staying on business would be agreed., • Keep abreast and update calendar of events (With revenue and reservations support) of all upcoming City-Wide Events at The Glasshouse International, football, sport, concert at St James Park, the Stadium of Light, Gateshead International Stadium as well as all non-accommodation music venues, conference and event venues., • Drive positive PR and create & publish social media activity (weekly) for the hotel, our brand, our team to generate and support a positive business reputation., • Attend and represent the hotel, our brand and Wyndham Hotels & Resorts at agency visits such as lunch and learn – some regional and national travel with overnight will be required to meet this need., • Assist in the completion of monthly, quarterly, annual business reporting and present online and in person at brand and owner business review meetings as part of the commercial leadership team., • Be conversant about the Hotel top performing accounts (success as well as challenge), • To monitor local Company activity and the local planning authorities to take advantage of any new business opportunities, research, contact and win business., • Attend and present at monthly hotels sales meetings and regional / national meetings. To attend weekly meetings with the General Manager., • Achieve and exceed set objectives set at monthly sales meetings and business., • Assist Reservations (groups & individual) Revenue Management and very occasionally reception in accommodation matters to maximise sales success and guest satisfaction, to win business and build business on the books., • To undertake any reasonable commercial, operational, financial request by your colleague managers, our team and GM to best serve the business, it’s clients and our clients and guests. SYSTEMS (Training provided but proficiency required) • The Job Holder must have previous experience in hotel sales particularly in the corporate sector, • The job holder must be a competent user of hotel systems (Revenue Management systems, PMS, Cvent and be able to use and articulate industry related reports, • Opera Cloud (PMS), Wynview (WH&R financial system) PowerPoint, Excel, Word Wyndham Community (Marketing B2B, management reporting, communications to EMEA and internal colleagues) - Must be proficient (HSM), • Lighthouse: Rate Parity and Rate shopping (HRM), • IDEAS: Pricing and Inventory management (HRM), • SynXis (Channel Management) (HSM, HRM, HresM), • STR: Market share management system (HSM, HRM) SKILLS & COMPETENCIES • Guest and client focused, • Business Acumen with drive for sales, • Self-drive with Get and Go, • Persuasive, • Communication – verbal, written in professional, welcoming, confident & friendly manner, • Networking, • Negotiation, • Impact & Influence, • Ambition, • Energetic, • Positive, • Team spirted The above is designed to help you in the understanding of your role and is not intended to be a definitive list of your duties, as flexibility in meeting the needs of the business, our clients and our guests. The incumbent will work for 4 days a week.

Job Title: Associate Product / Clinical Marketing Manager (Oncology Diagnostics) Status: Full Time Division: Commercial / Marketing Location: London-based (hybrid), remote (EU) considered for exceptional candidates Travel: Ability to travel up to ~25% of the time (primarily for conferences, partner meetings, and launch-related activities) Salary: Competitive Reporting: CEO, with structured, hands-on coaching from an executive-level marketing and commercial strategy consultant with deep experience in oncology and diagnostics Company Today, precision medicine coupled with advanced diagnostics is taking over. However, those innovations in medicine come with an ever-increasing price tag driven by more expensive and complicated solutions making them less accessible unless we do something about it. Signatur Biosciences was established with the mission of making cutting-edge diagnostic tools accessible to more patients around the world. As a startup we have developed a technology to profile complex molecular signatures in a single reaction using qPCR machines already in place in every biomedical lab around the world. Signatur Biosciences is a startup based in London, UK and in Liege, Belgium. We're worried about accessibility in precision diagnostics and are building a team of individuals who share our passion for solving this problem through close collaboration and a sense of urgency. We're building a different kind of company, where employees think like owners, act with authority, and collaborate closely with one another. We are seeking a highly motivated and driven Associate Product / Clinical Marketing Manager to join our team. In this role, under the direction of the CEO and with close, hands-on coaching from an executive-level marketing and commercial strategy consultant with deep experience in oncology diagnostics, you will be responsible for leading and shaping the product marketing and go-to-market strategy, directly contributing to the preparation and execution of product launches, while also developing high-quality marketing content, supporting congress and event preparation, and building competitive and market intelligence. If you are an intellectually curious self-starter with a passion for precision medicine and oncology, we’d love to speak with you! About the role This is an early-career, high-impact role for someone who wants to build a career in precision oncology diagnostics marketing while taking real ownership early. Working closely with the CEO, senior external consultants, and internal R&D, clinical, and regulatory colleagues, you will play a leading role in shaping product positioning and go-to-market strategy, and will be directly involved in preparing and executing product launches for SigBio’s oncology diagnostics. Through hands-on execution and structured exposure to senior-level decision-making, a strong performer in this role is expected to grow into a senior marketing leadership position as the company scales. Main Responsibilities Product Positioning (Supported Leadership) • Lead the development and evolution of product positioning for SigBio’s oncology diagnostics, aligned with clinical evidence, access goals, and long-term corporate strategy, • Contribute directly to defining value propositions relative to existing gold-standard tests, including access-expanding and differentiated use cases, • Support corporate strategy workstreams by translating strategic hypotheses into clear, decision-ready marketing narratives and materials Go-To-Market & Product Launch (Leadership) • Play a central role in preparing and executing product launches across RUO (Research use Only) / Early Access and EU regulated pathways, • Contribute to the design and rollout of Early Access / RUO programmes, including positioning, claims framing, and customer-facing materials, • Support EU go-to-market preparation, including launch sequencing, audience targeting, and dissemination strategy, • Map out reimbursement requirements and support Health Technology Assessment (HTA) engagement, in collaboration with external advisors and internal regulatory and clinical teams Marketing Content & Scientific Communication (Ownership) • Develop high-quality marketing materials, including slide decks, one-pagers, and clinical summaries for different audiences (oncologists, pathologists, laboratories, partners), • Translate complex clinical and scientific concepts into clear, credible, and compliant marketing narratives, • Support preparation of materials for scientific congresses and industry events (e.g. ESMO, ASCO), including posters, presentations, and booth content, • Work with Key Opinion Leaders to gather feedback and build advocacy for the product. Competitive & Market Intelligence (Ownership) • Track competing diagnostic tests, emerging technologies, and commercial models in oncology and precision diagnostics, • Monitor relevant scientific publications, clinical guidelines, and market developments, • Contribute to assay portfolio extension strategy by evaluating unmet medical needs, emerging clinical use cases, and market opportunities, • Support strategic assessment of new assay concepts by helping steer development direction based on clinical relevance, commercial potential, and portfolio fit, • Synthesize insights into structured internal updates to inform positioning, go-to-market decisions, portfolio prioritisation, and leadership discussions Technical Expertise • Develop a strong working understanding of molecular diagnostics, precision oncology workflows, and clinical decision-making pathways, • Understand regulatory distinctions (RUO vs regulated IVD) and their implications for marketing claims and communications, • Apply scientific rigor and accuracy to all external-facing materials Project and Product Delivery • Collect, synthesise, and communicate customer and market feedback to inform the development and refinement of diagnostic tests, • Actively contribute to new product development projects by providing market, clinical, and customer insights throughout the development lifecycle, • Support key commercial and strategic initiatives with structured, reliable execution, • Continuously improve internal marketing processes, templates, and content libraries Skills, Experience & Attributes Essential Skills/Experience • Degree in life sciences, biomedical sciences, biotechnology, or a related field, • Early-career profile with high learning agility and intellectual curiosity, • Exposure to oncology and diagnostics, preferably molecular or precision diagnostics, • Strong written and visual communication skills (slides, structured documents), • Ability to work effectively in ambiguous, evolving startup environments Desirable Skills/Experience • Prior experience in a diagnostics, medtech, or healthcare-focused company or agency, • Familiarity with scientific marketing, medical communications, or product marketing, • Exposure to commercialisation or go-to-market projects, • Direct sales exposure (a plus but not required) Key Competencies • Learning agility and intellectual curiosity, • Scientific thinking and attention to detail, • Clear, structured communication, • Ownership mindset and accountability, • Collaboration across technical and commercial teams Benefits • Competitive base salary plus equity participation, • Annual leave, • Health reimbursement, • Pension, • Opportunity for rapid professional growth through direct exposure to company leadership and senior commercial expertise As we continue to grow, our benefits package may evolve. The benefits outlined above are accurate as of the job posting date, but may differ at time of hire. Signatur Biosciences is an equal-opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.

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