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The Role CSL is looking for a Principal Programmer to take technical ownership of statistical programming across a compound or programme, not just a single study. You’ll be the person who sets how the programming gets done across multiple trials and through to submission, and the one a study team, a CRO or a regulator’s question ultimately lands with. This is still a hands-on role, and you’ll write and validate code when the work calls for it. Most of your impact, though, comes from the decisions upstream: how standards are applied across studies so an integrated analysis comes together cleanly, how CRO work is scoped and held to account, and how a submission package is built so it holds up under review. You’ll work as a peer to biostatistics, data management, medical writing and regulatory leads, and you’ll be in the room early enough to shape a programme’s analysis strategy rather than inherit it. Hybrid Based (3 days a week onsite) in Maidenhead Why It Matters A single well-programmed study is valuable. A programme where every study was built to the same standard, so pooled safety and efficacy analyses come together without months of rework, is what gets a submission over the line. This role sits at that level. You spot the inconsistency between two studies’ ADaM conventions before it becomes an ISS problem, push back on a CRO deliverable that technically meets spec but won’t survive a reviewer, and make the call on the trade-offs between speed, consistency and regulatory defensibility. When an agency query comes back, you’re the one who knows why the data was built the way it was. What You’ll Be Responsible For You’ll lead programming at the programme or compound level, across in-house and outsourced studies, from study setup through integrated analyses and regulatory submission. You’ll set direction for other programmers, internal and external, and help shape how the wider programming function works. • Serve as lead programmer for a compound or programme, overseeing programming across multiple clinical trials and ensuring consistency of standards and approach, • Lead the planning, specification and delivery of integrated analyses (ISS/ISE) and pooled datasets, and own the submission-ready data package, including define.xml, reviewer guides (cSDRG/ADRG) and conformance checks, • Define programming strategy for outsourced studies, set expectations for CROs and hold their deliverables to submission standard, • Act as the programming point of contact for regulatory submissions and agency queries, working with biostatistics and regulatory colleagues on responses, • Lead and mentor other programmers, providing technical direction, review and day-to-day guidance across the programme, • Contribute to departmental standards, macros, tools and process improvement, including the adoption of new approaches such as R-based workflows, • Take on hands-on programming and ad hoc analytical work (exploratory analyses, publication support, regulatory responses) as the programme requires Experience Required • Substantial statistical programming experience in pharmaceutical, biotech, CRO or clinical research settings, including lead programmer responsibility across multiple studies, • Expert SAS proficiency (Base/Macro/Stat/Graph); working experience with R or other languages is a strong plus, • Deep, practical knowledge of current CDISC standards (CDASH, SDTM, ADaM, define.xml) and how to apply them consistently across a programme, • Track record of leading integrated analyses (ISS/ISE) and delivering submission-ready data packages, • Direct experience of supporting regulatory submissions end to end (FDA required; PMDA, NMPA or EMA experience a plus), including responding to agency queries, • Experience of setting direction for and overseeing CRO and vendor programming work, • Experience of leading, mentoring or technically directing other programmers, • BSc in Computer Science, Mathematics, Statistics or a related field (MSc desirable); equivalent experience and certifications will also be considered

Senior Clinical Statistical Programmer (Portfolio Development / Biometrics / Programming) The Role CSL is looking for a Senior Programmer to take technical ownership of one or two clinical trials from first line of code to final submission package. This is a hands-on statistical programming role with real authority attached to it: you'll be the person a study team turns to when the data needs to hold up under regulatory scrutiny, and the person who decides how a dataset gets built, not just who builds it. You'll work alongside statisticians, data managers, medical writers and regulatory colleagues as a peer, not a downstream resource — reading protocols and SAPs early enough to shape how a study's analysis gets structured, then seeing that structure through to submission-ready SDTM and ADaM datasets, TFLs, and supporting documentation. Hybrid Based (3 days a week onsite) in Maidenhead Why It Matters Clinical data is only as useful as the programming behind it is trustworthy. Every regulatory decision downstream — every safety signal caught or missed, every submission accepted or queried — traces back to whether the datasets and outputs were built right the first time. This role sits at that pressure point. You're not just executing specifications; you're often the one writing them, catching the ambiguity in a protocol before it becomes a data problem three months later, and making the judgment calls that keep a study's analysis both scientifically sound and audit-ready. What You'll Be Responsible For You'll lead end-to-end programming for your assigned studies — in-house or outsourced — spanning the full clinical development lifecycle from study setup through analysis, reporting, and regulatory submission. That means building and validating datasets and outputs yourself where the work is done internally, and holding CRO-delivered work to the same bar where it isn't. You'll also be a technical reference point for less experienced programmers, and a contributor to how the wider programming function does its work. · Serve as lead programmer for one or two clinical trials, interpreting protocols, SAPs, data management plans, and CRF specifications to drive study setup and analysis · Design and validate SDTM and ADaM datasets, tables, figures, and listings, in partnership with study statisticians · Review and take ownership of CRO-produced deliverables, ensuring submission-ready quality before they go further · Lead specification and delivery of integrated analyses (e.g. ISS/ISE) and associated outputs when not handled by a CRO · Mentor other programmers on internal processes and standards, and contribute to departmental tools and process improvements · Take on ad hoc analytical work — regulatory query responses, exploratory analyses, publication support — as studies require it Experience Required · Experience of programming in pharmaceutical, biotech, CRO, or clinical research settings · Strong SAS proficiency (Base/Macro/Stat/Graph); familiarity with R or other languages is a plus · Working knowledge of current CDISC standards — CDASH, SDTM, ADaM, define.xml · Track record of producing and validating submission-ready TFLs and datasets, including ad hoc analytical requests · Experience supporting regulatory submissions (FDA required; PMDA, NMPA, or EMA experience a plus) · Comfort working with external vendors and CRO-managed data · BSc in Computer Science, Mathematics, Statistics or a related field — equivalent experience and certifications will also be considered

Senior Clinical Statistical Programmer (Portfolio Development / Biometrics / Programming) \n The Role \n CSL is looking for a Senior Programmer to take technical ownership of one or two clinical trials from first line of code to final submission package. This is a hands-on statistical programming role with real authority attached to it: you'll be the person a study team turns to when the data needs to hol... \n \n ZIPC1_UKTJ

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CSL is seeking a Senior Clinical Statistical Programmer to take technical ownership of one or two trials from first line of code to submission package. This hands-on role requires shaping data structure, building datasets, and delivering submission‑ready outputs with strong regulatory rigour. You will work alongside statisticians, data managers and regulatory colleagues to ensure datasets and outputs stand up to audit and regulatory scrutiny. #J-18808-Ljbffr

Gattaca is seeking an experienced CAM Programmer to join our Southwark-based manufacturing team.

Location: London SE1 Job Type: Full-time Salary: Up to £80,000 We are seeking an experienced CAM Programmer to join our growing manufacturing team in Southwark. This is a high-impact technical role focused on developing, optimising, and industrialising machining processes for advanced aerospace, defence, energy, and robotics components. You will be responsible for creating efficient CNC programs, validating manufacturing strategies, and supporting production teams to achieve exceptional quality, repeatability, and throughput. Working alongside machinists, engineers, and software developers, you will play a critical role in building one of the most advanced and digitally connected manufacturing facilities in the UK. The ideal candidate combines strong CAM expertise with a passion for precision engineering, continuous improvement, and data-driven manufacturing. • Create, simulate, verify, and optimise CNC programs across a range of machine tools., • Develop machining strategies for complex, high-precision components., • Select tooling, work holding, cutting parameters, and machining methods to maximise efficiency and quality., • Support first article prove-outs and process validation activities., • Continuously improve cycle times, machine utilisation, and manufacturing performance., • Design and refine fixturing and setup strategies to improve repeatability., • Support New Product Introduction (NPI) activities from design review through to production release., • Provide Design for Manufacture (DFM) feedback to engineering teams and customers., • Create and maintain machining documentation, setup sheets, and process standards., • Work closely with operators, machinists, engineers, and MasonOS software teams to improve manufacturing workflows and data collection., • Support the adoption of automation, probing technologies, and advanced machining techniques., • Strong CAM programming experience using Fusion 360, HyperMill, Mastercam, Siemens NX, or equivalent., • Proven experience programming complex CNC milling and/or turning operations., • Deep understanding of machining processes, tooling, work holding, feeds, speeds, and cutting strategies., • Ability to manufacture precision components to tight tolerances (±0.01mm and below where required)., • Experience interpreting complex engineering drawings and GD&T requirements., • Understanding of machining challenging materials such as aluminium, stainless steels, titanium, and Inconel., • Strong problem-solving skills and a continuous improvement mindset., • Comfortable working in a fast-paced, high-growth manufacturing environment., • 5-axis simultaneous machining., • Multi-axis mill-turn programming., • Experience with probing, automation, pallet systems, or lights-out manufacturing., • Knowledge of AS9100 and ISO9001 quality systems., • Aerospace, defence, energy, or other high-specification manufacturing experience., • Interest in robotics, automation, and digital manufacturing technologies., • The opportunity to shape machining strategy within a highly digitalised manufacturing environment., • Work on mission-critical components for aerospace, defence, energy, and robotics customers., • Access to advanced machine tools, automation systems, and proprietary manufacturing software., • Exposure to cutting-edge manufacturing technologies and continuous process development., • A high-performance culture focused on innovation, ownership, and continuous improvement. has context menu #J-18808-Ljbffr

Senior Clinical Statistical Programmer (Portfolio Development / Biometrics / Programming)The RoleCSL is looking for a Senior Programmer to take technical ownership of one or two clinical trials from first line of code to final submission package. This is a hands-on statistical programming role with real authority attached to it: you'll be the person a study team turns to when the data needs to hold up under regulatory scrutiny, and the person who decides how a dataset gets built, not just who builds it. You'll work alongside statisticians, data managers, medical writers and regulatory colleagues as a peer, not a downstream resource — reading protocols and SAPs early enough to shape how a study's analysis gets structured, then seeing that structure through to submission-ready SDTM and ADaM datasets, TFLs, and supporting documentation.*Hybrid Based (3 days a week onsite) in Maidenhead*Why It MattersClinical data is only as useful as the programming behind it is trustworthy. Every regulatory decision downstream — every safety signal caught or missed, every submission accepted or queried — traces back to whether the datasets and outputs were built right the first time. This role sits at that pressure point. You're not just executing specifications; you're often the one writing them, catching the ambiguity in a protocol before it becomes a data problem three months later, and making the judgment calls that keep a study's analysis both scientifically sound and audit-ready.What You'll Be Responsible ForYou'll lead end-to-end programming for your assigned studies — in-house or outsourced — spanning the full clinical development lifecycle from study setup through analysis, reporting, and regulatory submission. That means building and validating datasets and outputs yourself where the work is done internally, and holding CRO-delivered work to the same bar where it isn't. You'll also be a technical reference point for less experienced programmers, and a contributor to how the wider programming function does its work.· Serve as lead programmer for one or two clinical trials, interpreting protocols, SAPs, data management plans, and CRF specifications to drive study setup and analysis· Design and validate SDTM and ADaM datasets, tables, figures, and listings, in partnership with study statisticians· Review and take ownership of CRO-produced deliverables, ensuring submission-ready quality before they go further· Lead specification and delivery of integrated analyses (e.g. ISS/ISE) and associated outputs when not handled by a CRO· Mentor other programmers on internal processes and standards, and contribute to departmental tools and process improvements· Take on ad hoc analytical work — regulatory query responses, exploratory analyses, publication support — as studies require itExperience Required· Experience of programming in pharmaceutical, biotech, CRO, or clinical research settings· Strong SAS proficiency (Base/Macro/Stat/Graph); familiarity with R or other languages is a plus· Working knowledge of current CDISC standards — CDASH, SDTM, ADaM, define.xml· Track record of producing and validating submission-ready TFLs and datasets, including ad hoc analytical requests· Experience supporting regulatory submissions (FDA required; PMDA, NMPA, or EMA experience a plus)· Comfort working with external vendors and CRO-managed data· BSc in Computer Science, Mathematics, Statistics or a related field — equivalent experience and certifications will also be considered #J-18808-Ljbffr

Job Title: AI Trainee Engineer – £45,000–£75,000 – Job Programme This is a self-funded programme that leads to employment, fees apply. Job Guarantee Complete the programme and get a job, or get your course fees back. Looking to start a career in AI Engineering? We are offering a structured pathway into AI Engineering, designed to help you enter one of the fastest-growing sectors in tech with no prior experience. This opportunity includes training, support, and access to our specialised recruitment support for job roles across the UK. No prior experience required. Train online at your own pace and become job-ready in as little as a few weeks. Our programme includes: • Official AWS Certified Cloud Practitioner certification, • Training in Python, Machine Learning, and AI systems, • Hands-on projects using real-world AI tools and technologies, • Professional CV and LinkedIn support, • Interview preparation, • Dedicated recruitment support until placed, • Personalised 1-1 tutor support, • Hands-on projects to build your AI portfolio Flexible, affordable, achievable To make things easier, we offer flexible payment options, allowing you to spread the cost of your training over 12 months so you can get qualified without financial pressure. Salary expectations: • AI Engineer: £45,000 – £60,000, • Machine Learning Engineer: £60,000 – £75,000, • Progression into senior AI roles with higher earning potential We support you into employment We focus on outcomes, not just training. ITOL Recruit has over 15 years of experience supporting candidates into roles across AI, machine learning, and data science roles. From the beginning of your journey to the end, you are supported by qualified tutors, and at the end, our specialised recruitment team helps you secure your first job role. Apply now to get started.

CSL in Maidenhead is seeking a Principal Programmer to take technical ownership of statistical programming across a programme of trials. You’ll set how the programming is done across multiple studies, lead both in-house and CRO work, and ensure submission-ready data packages. You will mentor other programmers and shape standards for integrated analyses, while remaining hands-on when required. This hybrid role is based in Maidenhead with three days onsite. #J-18808-Ljbffr

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Senior Clinical Statistical Programmer to own the programming for one or two trials from setup to submission, collaborating with statisticians, data managers and regulatory colleagues.

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