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Senior Pharmacovigilance (PV) Operations Specialist (UK) CellCentric is a clinical-stage biopharmaceutical company with a science-driven and patient-focused mission. Our drug inobrodib is a first-in-class p300/CBP inhibitor that is being developed for the treatment of multiple myeloma and other specific cancers. Our aim is to develop inobrodib as quickly and as effectively as possible for the benefit of patients. Position Summary The Senior Pharmacovigilance (PV) Operations Specialist will have prior experience in preparing the safety data package for submission to regulatory authorities (e.g. FDA, EMA) for a New Drug Application (NDA). The individual will be dynamic and a strong team player, collaborating cross-functionally with CellCentric’s PV Partner, Clinical Research Organisations (CROs) and internal functional teams including Clinical Operations, Medical Affairs, Data Management and Biostatistics, Regulatory and Quality to maintain high standards of patient safety and regulatory compliance. The individual will support the day-to-day operational activities of the Safety and Pharmacovigilance function at CellCentric working across the inobrodib program, ensuring the robust oversight of CellCentric PV Partner who are responsible for safety event processing, quality documentation, and reporting of safety information in compliance with global regulatory requirements. The individual will contribute to the success of the team and organization by delivering on role-specific responsibilities while upholding CellCentric core working behaviors of Trust and Respect, Communication and Feedback, Accountability and Reliability, Objectivity, and Team Balance and Enablement. Key Responsibilities • Lead the preparation, review, and submission of safety data packages for regulatory filings, including NDAs and Integrated Summaries of Safety (ISS), ensuring compliance with FDA, ICH, GVP, and other global regulatory requirements, • Provide safety surveillance across pre-approval and post-marketing phases, including signal detection, trend analysis, benefit–risk evaluation, and contribution to risk management planning, • Oversee and support pharmacovigilance operations, including end-to-end processing of Individual Case Safety Reports (ICSRs) from clinical trials, spontaneous reports, literature, medical information, and post-marketing sources, ensuring accurate data entry, coding (MedDRA, WHO-DD), narrative development, quality review, medical assessment, and compliance with global reporting timelines, • Provide oversight and governance of the CellCentric pharmacovigilance partner and other vendors, ensuring activities are conducted in accordance with CellCentric SOPs, study-level Safety Management Plans, and regulatory requirements, • Support the preparation, review, and submission of expedited and periodic safety reports, including SUSARs, SAEs, DSURs, PSURs/PBRERs, in alignment with defined partner responsibilities, • Maintain inspection-ready safety documentation, including case records and Trial Master File (TMF) components, and lead or support regulatory inspections, audits, and internal quality reviews from a pharmacovigilance perspective, • Support safety data reconciliation activities between pharmacovigilance databases, clinical databases, and CRO systems to ensure data integrity and consistency, • Identify, assess, and escalate safety or compliance risks in a timely manner and lead or support corrective and preventive action (CAPA) activities related to safety operations, • Collaborate cross-functionally with Clinical Operations, Data Management, Biometrics, Medical Affairs, Regulatory Affairs, Quality, and external partners to ensure accurate and timely safety data flow and effective issue resolution, • Participate in and support safety review meetings, signal management discussions, and governance forums as applicable, • Contribute to the development, maintenance, and training of pharmacovigilance SOPs, work instructions, and related training materials, • Bachelor’s degree in life sciences, nursing, pharmacy, public health, or a related field, • (Advanced degree preferred but not required), • Typically 5+ years of experience in pharmacovigilance, with specific experience in CRO, biotech or pharmaceutical company drug safety/clinical safety operations supporting NDA submission, • Experience in biotech or early-stage development environments is preferred, • Experience in both clinical trial and post-marketing safety, • Hands-on experience with ICSR processing and global safety reporting requirements, • Proficiency with PV safety database systems (e.g., Argus, ARISg, Veeva Vault Safety), • Strong knowledge of global pharmacovigilance regulations (FDA, EMA, ICH, CIOMS), • Deep understanding of MedDRA and WHO-Drug coding conventions, • Strong attention to detail and ability to manage multiple priorities in a regulated environment, • Proven ability to work independently and collaboratively in cross-functional teams, • Proficiency in Microsoft Office applications (Excel, Word, PowerPoint), • Experience with audit readiness, including leading or supporting regulatory inspections and internal audits, • Prior experience working with vendors and/or CROs, • Pharmacovigilance or Drug Safety certification (e.g., DIA, PV professional certifications), • Demonstrated integrity, openness, and respect, with the ability to build trust and credibility, • Strong accountability and consistent delivery on commitments, • Trust and Respect: Act with integrity, honesty, and openness to build strong, credible relationships., • Communication and Feedback: Share information clearly, listen actively, and engage in a culture of constructive feedback., • Accountability and Reliability: Take ownership for performance, be dependable, and support others to achieve collective goals., • Objectivity: Align on common objectives and use facts and data to reach fair, effective decisions. At CellCentric, we believe success is built on great teams. By embodying these working behaviors, every member contributes to a high-performing, supportive, and inclusive culture where individuals and the business thrive together. Everything we do is underpinned by our common vision and goal to improve the lives of people with cancer. How to Apply Please send your CV and covering letter to

Aftersales Executives Certain Advantage is hiring for Aftersales Executives based in Macclesfield This is an immediate temp role for approximately 2 months could be longer, possibly temp to perm. The Company We’re working with a business that’s a leading Automotive business in Macclesfield. If you’re looking to be part of a forward-thinking and supportive client that values its people, then this is a great temp to perm opportunity, The Role: We’re looking for an enthusiastic and proactive Aftersales Executive to join their existing Aftersales team. If you thrive in a fast-paced environment, have strong organisational and communication skills this is the perfect temp to perm role for you! Key Responsibilities • Handle customer enquiries regarding aftersales services and support, • Schedule and manage service appointments while maintaining optimal customer communication, • Collaborate with service and technical teams to ensure timely service delivery, • Provide customers with updates and resolutions regarding their service experiences, • Promote aftersales products and services to enhance customer satisfaction, • Contribute to achieving aftersales performance targets £12.98 an hour. £30,387, OTE £45,000 Shifts are working 45 hours a week over 5 days. The client is open 7.30am-6.30pm Monday to Friday and 1 in 3 Saturdays. Start date ASAP The Individual The successful candidate will have the following experience: • Previous experience in an aftersales or customer service role in the automotive industry, • Previous Keyloop experience, • Exceptional interpersonal and communication skills, • Strong organisational capabilities with attention to detail, • A customer-focused mindset with a commitment to service excellence, • Ability to work effectively in a team-oriented and fast-paced environment, • A valid driver's licence is essential Working with Certain Advantage We go the extra mile to find the best people for the job. If you’re hunting for a role where you can make an impact and grow your career, we’ll work with you to find it. We work with businesses across the UK to find the best people in Business Support, Legal, Finance, Marketing, HR, IT and Engineering. If this job isn’t for you, head to certainadvantage.co.uk and register for job alerts and career guidance tips.

Graduate Telemarketing Executive (Emailing, calling, LinkedIn and Telemarketing) Certain Advantage is hiring for a Graduate Telemarketing Executive for a fantastic client based in Macclesfield. The role is on a temp to permanent basis, with excellent benefits. £12.64 an hour, plus bonus (Up to £400 a month) The Role: Are you confident on the phone and motivated by results? We’re looking for an enthusiastic Graduate Telemarketing Executive to join a growing team in a hybrid role combining office and home-based working. You’ll play a key part in generating new business opportunities for our clients – making outbound B2B calls, researching potential leads, and booking qualified appointments for sales teams. This is a great opportunity for someone with a passion for communication, persistence, and building relationships. Key Responsibilities: • Making outbound B2B calls to prospective customers across various sectors., • Conduct outbound calling, emailing and LinkedIn outreach to generate qualified leads., • Generating qualified leads and booking appointments for client sales team, • Conducting business research to identify new opportunities and decision-makers, • Maintaining accurate records and follow-ups in the CRM system, • Working towards achievable call and conversion targets The individual We’re looking for people who have: Previous experience in B2B telemarketing, lead generation, or appointment setting preferred but not essential) • Strong business acumen and ability to quickly understand different industries, • Excellent telephone manner, communication and listening skills, • Confident, proactive, and target-driven attitude, • Strong research skills and attention to detail, • Self-motivated with the ability to work independently and as part of a team, • Comfortable using CRM systems and Microsoft Office, • A team player, • Comfortable using LinkedIn and email as part of multichannel outreach strategy Working with Certain Advantage We go the extra mile to find the best people for the job. If you’re hunting for a role where you can make an impact and grow your career, we’ll work with you to find it. We work with businesses across the UK to find the best people in Business Support, Legal, Finance, Marketing, HR, IT and Engineering. If this job isn’t for you, head to certainadvantage.co.uk and register for job alerts and career guidance tips.

Are you an experienced Tax Valuation Professional looking for a new opportunity to showcase your skills and grow your career? All levels from qualified Seniors, to those looking for a Director/Associate Partner move. Our client, a leading professional services firm, is seeking a motivated and talented individual like you to join their team (level open based on experience). With a portfolio of valuation clients, you will play a crucial role in ensuring the timely completion and quality delivery of engagements. This is your chance to support Directors and Partners, build strong client relationships, and drive marketing and business development initiatives. Your responsibilities will include, but not limited to: • Ensuring compliance with the organisation's risk management and client take-on procedures., • Effectively managing valuation engagements from start to finish., • Conducting robust technical valuation analyses for various purposes, such as accounting, tax, commercial, and forensic engagements., • Creating clear and concise valuation reports that are accessible to non-technical readers., • Significant valuation experience gained ideally from another professional services firm., • Proficiency in various valuation techniques, including discounted cash flow, multiples analysis, and intangible asset valuation techniques., • The ability to interpret financial statements within the context of valuations., • Strong commercial acumen and a deep understanding of value drivers for different assets., • Excellent business writing, analytical, and Excel modelling skills., • Effective written and oral communication abilities.

Finance Manager | Location: Cheshire (Hybrid) | £55,000 - £60,000 + 10% bonus | PE Backed Axon Moore have partnered with a PE backed business in Cheshire who are looking for a Finance Manager on a full time permanent basis. They have been a real market leader in their industry for 20+ years and after recently acquiring one of its competitors, are looking to continue that growth journey through organic growth and further acquisitions.Reporting to a high calibre FD, we're looking for a strong leader who can oversee a team of 3 direct reports. Responsibilities include: • Manage a finance team of 3, providing mentoring and development to ensure high performance and growth., • Own the budgeting cycle, produce regular forecasts, and act as a strategic business partner to Marketing, Sales & Operational teams, • Oversee multi-currency treasury activities and deliver both short- and long-term cashflow forecasts., • Manage and drive month-end and year-end close processes, delivering management accounts, statutory accounts, and board reporting., • Produce financial and operational forecasts to support planning, decision-making, and performance monitoring, • Provide meaningful financial insight through analysis, dashboards, and performance reporting., • Maintain strong financial controls, enhance processes and documentation, and review balance sheet reconciliations and journal entries., • Oversee inventory accounting and stock takes to ensure accuracy and completeness. Ideal candidate:, • CIMA/ACCA/ACA qualified, QBE will be considered, • Strong leadership skills with a track record of managing direct reports, • Experience collaborating with stakeholders and communicating financial insights. For more information please apply to this advert or contact Danny Kay at Axon Moore on .

Telemarketing Executive / Business Development Representative (Emailing, calling, LinkedIn and Telemarketing) Certain Advantage is hiring for a Telemarketing Executive/Business Development Representative for a fantastic client based in Macclesfield. The role is on a temp to permanent basis, with excellent benefits. £12.64 an hour, plus bonus (Up to £400 a month) The Role: Are you confident on the phone and motivated by results? We’re looking for an enthusiastic Telemarketing Executive / Business Development Representative to join a growing team in a hybrid role combining office and home-based working. You’ll play a key part in generating new business opportunities for our clients – making outbound B2B calls, researching potential leads, and booking qualified appointments for sales teams. This is a great opportunity for someone with a passion for communication, persistence, and building relationships. Key Responsibilities: Making outbound B2B calls to prospective customers across various sectors. Conduct outbound calling, emailing and LinkedIn outreach to generate qualified leads. Generating qualified leads and booking appointments for client sales team Conducting business research to identify new opportunities and decision-makers Maintaining accurate records and follow-ups in the CRM system Working towards achievable call and conversion targets Building strong relationships with clients through clear and professional communicationHybrid – Office based in Macclesfield (2 days a week at home and 3 days in the office). Monday–Thursday 8.30am–5.00pm, Friday 8.30am–1.00pm (36.5 hours per week) Early Friday finish, regular team, and social events. The individual We’re looking for people who have: Previous experience in B2B telemarketing, lead generation, or appointment setting preferred but not essential) Strong business acumen and ability to quickly understand different industries Excellent telephone manner, communication and listening skills Confident, proactive, and target-driven attitude Strong research skills and attention to detail Self-motivated with the ability to work independently and as part of a team Comfortable using CRM systems and Microsoft Office A team player Comfortable using LinkedIn and email as part of multichannel outreach strategy Working with Certain Advantage We go the extra mile to find the best people for the job. If you’re hunting for a role where you can make an impact and grow your career, we’ll work with you to find it. We work with businesses across the UK to find the best people in Business Support, Legal, Finance, Marketing, HR, IT and Engineering. If this job isn’t for you, head to (url removed) and register for job alerts and career guidance tips

Aftersales Executives Certain Advantage is hiring for Aftersales Executives based in Macclesfield This is an immediate temp role for approximately 2 months could be longer, possibly temp to perm. The Company We’re working with a business that’s a leading Automotive business in Macclesfield. If you’re looking to be part of a forward-thinking and supportive client that values its people, then this is a great temp to perm opportunity, The Role: We’re looking for an enthusiastic and proactive Aftersales Executive to join their existing Aftersales team. If you thrive in a fast-paced environment, have strong organisational and communication skills this is the perfect temp to perm role for you! Key Responsibilities Handle customer enquiries regarding aftersales services and support Schedule and manage service appointments while maintaining optimal customer communication Collaborate with service and technical teams to ensure timely service delivery Provide customers with updates and resolutions regarding their service experiences Promote aftersales products and services to enhance customer satisfaction Contribute to achieving aftersales performance targets £12.98 an hour. £30,387, OTE £45,000 Shifts are working 45 hours a week over 5 days. The client is open 7.30am-6.30pm Monday to Friday and 1 in 3 Saturdays. Start date ASAP The Individual The successful candidate will have the following experience: Previous experience in an aftersales or customer service role in the automotive industry Previous Keyloop experience Exceptional interpersonal and communication skills Strong organisational capabilities with attention to detail A customer-focused mindset with a commitment to service excellence Ability to work effectively in a team-oriented and fast-paced environment A valid driver's licence is essential Working with Certain Advantage We go the extra mile to find the best people for the job. If you’re hunting for a role where you can make an impact and grow your career, we’ll work with you to find it. We work with businesses across the UK to find the best people in Business Support, Legal, Finance, Marketing, HR, IT and Engineering. If this job isn’t for you, head to (url removed) and register for job alerts and career guidance tips

Are you a recent graduate with a passion for business and the drive to succeed? The UK's largest supplier of electrical equipment to business and trade customers is offering an exciting opportunity to join their comprehensive graduate programme designed to cultivate the next generation of sales leaders and managers. About the Company The company you'll be joining recognises the importance of nurturing talent and building a strong succession plan. Their graduate sales and business management programme was established over a decade ago to bring in bright and ambitious graduates who are eager to learn about business operations. They seek individuals who are money-motivated and aspire to become effective salespeople and future managers. Graduate Training Programme: First 6 months Develop a core knowledge of how the business operates - warehouse, logistics, supply chain, administration, IT software, and marketing. Get hands-on with the vast product range and learn about different manufacturers and the electrical distribution industry. Start building relationships, making deals and advising customers face-to-face over the trade counter e.g. electricians, contractors and tradespeople. Begin your formal sales training course and network with other Graduate Trainees. Complete workbook assessments to underpin your learning and development and receive financial incentives for each one passed to a required standard.6-12 months Move to internal sales account management, engaging with business customers over the phone e.g. construction companies, local government authorities, housing developers and hotels. Learn business development strategies and how to target and win new trading accounts.12 months and beyond Progress to a diverse business-to-business field sales management position, with increased earning potential and bigger bonuses. Travel locally in your company car, meeting clients, discussing projects, and arranging social activities. Work towards running your own business in the group, learning about staff management, purchasing, profit and loss, etc. The business operates in a decentralised manner, allowing local managers to make informed decisions that drive the business forward.Apply Today to Find Out More If you're ready to kick-start your career in a company that values innovation, autonomy, and career development, this is the graduate program for you. We seek graduates who are money-motivated, relationship builders, competitive, and driven. If you have a passion for sales and the ability to build lasting relationships, apply today! Please note, a full UK driving licence is required for this role

Spanish Speaking Telemarketing Executive / Business Development Representative (Emailing, calling, LinkedIn and Telemarketing) Certain Advantage is hiring for a Spanish Speaking Telemarketing Executive/Business Development Representative for a fantastic client based in Macclesfield. The role is on a permanent basis, with excellent benefits. £25,000 basic £29,500 OTE (Up to £400 a month) The Role: Are you confident on the phone and motivated by results? We’re looking for an enthusiastic Spanish Speaking Telemarketing Executive / Business Development Representative to join a growing team in a hybrid role combining office and home-based working. You will be contacting Spanish-speaking businesses and decision-makers to introduce products/services and generate qualified leads. This is a great opportunity for someone with a passion for communication, persistence, and building relationships. Key Responsibilities: Making outbound calls to Spanish-speaking prospects. Conduct outbound calling, emailing and LinkedIn outreach to generate qualified leads. Generating qualified leads and booking appointments for client sales team. Conducting business research to identify new opportunities and decision-makers. Maintaining accurate records and follow-ups in the CRM system. Working towards achievable call and conversion targets. Building strong relationships with clients through clear and professional communication. Occasionally supporting the English-speaking team when needed. Hybrid – Office based in Macclesfield (2 days a week at home and 3 days in the office). Monday–Thursday 8.30am–5.00pm, Friday 8.30am–1.00pm (36.5 hours per week) Early Friday finish, regular team, and social events. The individual We’re looking for people who have: Previous experience in B2B telemarketing, lead generation, or appointment setting preferred but not essential) Fluent in Spanish (native or business-level). Strong business acumen and ability to quickly understand different industries. Excellent telephone manner, communication and listening skills. Confident, proactive, and target-driven attitude. Strong research skills and attention to detail. Self-motivated with the ability to work independently and as part of a team. Comfortable using CRM systems and Microsoft Office. A team player. Comfortable using LinkedIn and email as part of multichannel outreach strategy Working with Certain Advantage We go the extra mile to find the best people for the job. If you’re hunting for a role where you can make an impact and grow your career, we’ll work with you to find it. We work with businesses across the UK to find the best people in Business Support, Legal, Finance, Marketing, HR, IT and Engineering. If this job isn’t for you, head to (url removed) and register for job alerts and career guidance tips

We are recruiting on behalf of a growing advertising business in Macclesfield who are looking for a Sales Executive to join their team. This role is focused on building relationships, making sales, and earning commission through consistent performance. If you have telesales experience and enjoy turning conversations into long-term clients, this is a strong opportunity to progress your career. The Role You will make calls to businesses, develop relationships, understand client needs, and offer solutions that deliver. You will work with the marketing team to prepare proposals and manage your pipeline to consistently meet and exceed targets. Staying informed on market activity and opportunities is an important part of the role. Success in this position is directly linked to your effort and results. The Candidate The client is looking for someone with previous telesales experience in any sector. You should be confident on the phone, able to build rapport quickly, target-driven, organised, and motivated by commission. Ambition and a desire to progress in sales are essential. What’s On Offer * A starting salary of £25,000 with uncapped commission and realistic earnings of £40,000 plus * Monday to Friday working hours from 9:00am to 4:30pm * Clear progression opportunities within a growing business * A supportive team environment * Benefits including pension If you are professional, motivated, and ready to turn your skills into tangible results, this is an excellent opportunity. Apply today to take the next step in your sales career

Sales Executive - Corporate Advertising Sector Location: Macclesfield (Office-Based with Hybrid Incentive) Salary: Up to £27,000 basic salary OTE: £45,000-£50,000 (Year 1) Job Type: Full-time, Permanent About the Role We're looking for a confident and motivated Sales Executive to join a specialist advertising sales team focused on corporate clients. You will be selling premium advertising solutions within a professional sector, offering high-value packages that support businesses' marketing and branding goals. This role is ideal for a driven salesperson who enjoys building strong relationships with key decision-makers in a B2B environment. Key Responsibilities Sell advertising space and marketing solutions to corporate clients Make outbound calls to prospects and build long-term business relationships Manage your sales pipeline and activity using a CRM system Work towards ambitious sales targets within a positive, team-focused cultureWhat You'll Love Up to £27,000 basic salary Realistic first-year OTE of £45,000-£50,000 Comprehensive training and ongoing coaching Opportunity to sell premium advertising packages Clear progression routes within the business Supportive and target-driven team environmentIdeal Candidate Strong communicator with excellent relationship-building skills Comfortable selling higher-value advertising solutions to business clients Organised, motivated, and results-driven Experience in B2B sales or advertising is advantageous but not essential

Telemarketing Executive / Business Development Representative (Emailing, calling, LinkedIn and Telemarketing) Certain Advantage is hiring for a Telemarketing Executive/Business Development Representative for a fantastic client based in Macclesfield. The role is on a temp to permanent basis, with excellent benefits. £12.64 an hour, plus bonus (Up to £400 a month) The Role: Are you confident on the phone and motivated by results? We’re looking for an enthusiastic Telemarketing Executive / Business Development Representative to join a growing team in a hybrid role combining office and home-based working. You’ll play a key part in generating new business opportunities for our clients – making outbound B2B calls, researching potential leads, and booking qualified appointments for sales teams. This is a great opportunity for someone with a passion for communication, persistence, and building relationships. Key Responsibilities: Making outbound B2B calls to prospective customers across various sectors. Conduct outbound calling, emailing and LinkedIn outreach to generate qualified leads. Generating qualified leads and booking appointments for client sales team Conducting business research to identify new opportunities and decision-makers Maintaining accurate records and follow-ups in the CRM system Working towards achievable call and conversion targets Building strong relationships with clients through clear and professional communicationHybrid – Office based in Macclesfield (2 days a week at home and 3 days in the office). Monday–Thursday 8.30am–5.00pm, Friday 8.30am–1.00pm (36.5 hours per week) Early Friday finish, regular team, and social events. The individual We’re looking for people who have: Previous experience in B2B telemarketing, lead generation, or appointment setting preferred but not essential) Strong business acumen and ability to quickly understand different industries Excellent telephone manner, communication and listening skills Confident, proactive, and target-driven attitude Strong research skills and attention to detail Self-motivated with the ability to work independently and as part of a team Comfortable using CRM systems and Microsoft Office A team player Comfortable using LinkedIn and email as part of multichannel outreach strategy Working with Certain Advantage We go the extra mile to find the best people for the job. If you’re hunting for a role where you can make an impact and grow your career, we’ll work with you to find it. We work with businesses across the UK to find the best people in Business Support, Legal, Finance, Marketing, HR, IT and Engineering. If this job isn’t for you, head to (url removed) and register for job alerts and career guidance tips