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Our client is an established, award-winning architectural practice with a strong reputation across Healthcare, Education, Defence, Heritage and Commercial architecture. Following the successful acquisition of several major projects and frameworks, they are looking to strengthen their established team with an experienced architectural leader who can play a key role in the continued growth and development of the practice. With a significant pipeline of secured work, including major Healthcare and Commercial frameworks, this is an exciting opportunity for an ambitious Associate or Director to progress towards equity partnership within a well-established practice. The successful individual will have the opportunity to take on a strategic position, combining project leadership with business development, client relationship management and the development of new opportunities. The role will involve overseeing a varied portfolio of projects, from Healthcare and Education schemes through to Defence, Commercial refurbishments, new-builds and listed or heritage buildings. Project values typically range from £1m-£2m, with larger schemes extending up to £10m. You will take a leading role in the delivery of projects, maintaining strong relationships with clients, consultants and contractors while providing strategic direction and technical oversight to project teams. All projects are Partner-led, with the successful individual taking responsibility for multiple schemes and providing senior-level input on project delivery, coordination, technical matters and problem solving. The role will combine hands-on project leadership with the wider responsibilities of running and growing an architectural practice. You will oversee project teams, provide technical guidance and support the development of Architects and Architectural Assistants, while maintaining responsibility for project performance, client relationships and the successful delivery of schemes. Alongside project delivery, you will be instrumental in developing existing client relationships, identifying new business opportunities and strengthening the practice's position across its key sectors. The practice places particular importance on experience with Higher-Risk Buildings (HRBs) and Building Regulations Principal Designer (BRPD) responsibilities. Experience in these areas would be highly advantageous, particularly for candidates with a background in Healthcare, Commercial or Education projects. The position would suit an established Associate Architect or Director looking to take the next step in their career, or an experienced Architect with a strong track record of leadership, commercial awareness and business development. There is a genuine opportunity to progress towards equity partnership within a few years, depending on the individual's experience, contribution and ambitions. Salary & Benefits • Salary of £65,000-£70,000, dependent on experience., • Hybrid working - typically 3 days in the office / 2 days remote, • 24 days annual leave plus bank holidays., • Pension scheme., • Private healthcare., • Professional memberships paid for., • Cycle to work and other employee benefits., • Regular networking and industry events., • Office trips and team activities., • Opportunity to lead and influence a growing portfolio of high-quality architectural projects., • Genuine opportunity to progress towards equity partnership within a few years., • Equity ownership and profit share upon appointment as an equity Partner., • Company-funded car upon appointment as an equity Partner., • The opportunity to influence business development, client relationships and the future direction of an established, award-winning practice. Associate Architect Requirements • Qualified Architect with substantial post-Part 3 experience and a strong track record of architectural project delivery., • Proven experience operating at Associate, Director or equivalent senior leadership level, or demonstrable readiness to step into an Associate position with a clear pathway towards partnership., • Strong experience leading projects from concept through to completion, with excellent technical and design capability., • Proven ability to manage client relationships, lead project teams and oversee multiple projects simultaneously., • Experience providing senior technical oversight, coordinating project teams and supporting the development of less experienced Architects and Architectural Assistants., • Demonstrable business development experience, including identifying opportunities, developing client relationships and contributing to the successful acquisition of new work., • Experience working within frameworks and managing relationships with key clients would be highly advantageous., • Strong commercial awareness, with the ability to contribute to financial performance, resource planning and the wider strategic direction of the practice., • Experience working on Higher-Risk Buildings (HRBs), with a strong understanding of the associated technical, regulatory and compliance requirements., • Experience undertaking Building Regulations Principal Designer (BRPD) responsibilities, or a strong understanding of the relevant legislation and requirements., • Good knowledge in either Revit or AutoCAD., • Strong communication, negotiation and leadership skills, with the ability to represent the practice confidently at client meetings and industry events., • A proactive, entrepreneurial approach, with the ambition to help drive the continued growth and success of the business. If you're an experienced architectural leader looking for a role that combines project delivery, strategic influence and business development, this is an excellent opportunity to join an established Oxford practice with a strong pipeline of secured work and a genuine pathway towards equity partnership. Bennett and Game Recruitment are a multi-disciplined technical recruitment agency based in Chichester, West Sussex operating across the UK with specialist teams covering a range of industries. We are acting as a Recruitment Agency in relation to this vacancy, and in accordance with GDPR by applying you are granting us consent to process your data, contact you about the services we offer, and submit your CV for the role you have applied for. JBRP1_UKTJ

Job DescriptionGeneral Summary:The Executive Director, Drug Metabolism & Pharmacokinetics, will lead the DMPK team at our Oxford site and will be part of the Global DMPK and Oxford Site leadership teams. The responsibilities of the role include developing and executing the strategy and operations of the Oxford DMPK team, as well as the scientific and managerial coordination of its groups and employees. This role will optimise interdisciplinary activities within DMPK and integrate activities with those of the other sites and departments, and thus, play a major role in shaping the direction of the overall Vertex portfolio. Using deep scientific expertise and strong leadership skills, this role will provide strategic and scientific direction to help advance the discovery and development of transformational therapies for serious unmet medical needs at Vertex.Key Duties and Responsibilities:Develop a strategy and vision for the Oxford DMPK team that is aligned with the Global DMPK and Vertex R&D vision/missionDevelop and execute DMPK scientific strategies to address ADME challenges in discovery and development programsBuild and maintain strong collaborative partnerships with Medicinal Chemistry, Biology, Preclinical Safety, Clinical Pharmacology, CMC and other R&D disciplines to advance Vertex programs through discovery and development.Represent DMPK function on drug discovery and development teams, at the Oxford site and with Vertex governance bodiesImplement innovative technologies and approaches to enhance scientific impact and/or efficiencies.Provides scientific and managerial leadership to their team in prioritising and executing on key deliverables and project needsEnsure completion of necessary DMPK regulatory documentation and reports to support drug development, including Investigator Brochures, INDs (or equivalent), and marketing applications.Hire, develop, manage and retain key talent to maintain a high-performing team. Develop internal and external sourcing strategies and liaise across sites to best meet project needs. Contribute to developing Global DMPK resource allocation, staffing needs, expenses, and capital budgeting, as well as implementation plans. Participate in the review of business development opportunitiesKnowledge and Skills:Strong management and leadership skills, with emphasis on developing and mentoring junior scientists to create a high-performing teamSuccessful track record and experience in a DMPK lead role on multiple R&D teams across more than one therapeutic area. Extensive experience working with small molecules is a must. Additional expertise and familiarity with one or more other modalities (e.g., protein, antibody and nucleic acid therapeutics, cell and gene therapies) is desired.Deep scientific and strategic expertise in various components of DMPK science such as in vitro and in vivo ADME assays, mass spectrometry and bioanalysis, pharmacokinetic data analysis, biotransformation/disposition pathways, drug interaction risk assessment and human dose and drug interaction predictions. Additional skills in areas such as transporter science, enzymology and PK/PD and PBPK modelling will be a plus.Ability to critically evaluate and implement new science and technology as it relates to the discovery and development of new medicinesExcellent verbal, written and interpersonal communication skills, and ability to develop and grow strong cross-site/function collaborationsEducation and Experience:Proven experience in a similar role is required after a PhD or the equivalent combination of education and experience.At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.Flex Designation:On-Site DesignatedFlex Eligibility Status:In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.#LI-OnsiteCompany InformationVertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.comSummaryLocation: Oxford, United KingdomType: Full time

At the Ellison Institute of Technology (EIT), we’re on a mission to translate scientific discovery into real world impact. We bring together visionary scientists, technologists, engineers, researchers, educators and innovators to tackle humanity’s greatest challenges in four transformative areas: Health, Medical Science & Generative Biology Food Security & Sustainable Agriculture Climate Change & Managing CO₂ Artificial Intelligence & Robotics This is ambitious work - work that demands curiosity, courage, and a relentless drive to make a difference. At EIT, you’ll join a community built on excellence, innovation, tenacity, trust, and collaboration, where bold ideas become real-world breakthroughs. Together, we push boundaries, embrace complexity, and create solutions to scale ideas from lab to society. Welcome to the Generative Biology Institute: Led by Founding Director Jason Chin, the Generative Biology Institute (GBI) at the Ellison Institute of Technologyis tackling the key challenges in making biology engineerable, and thereby releasing the unrivalled power of biology for the benefit of humanity. The vision of GBI is to lay the foundations for engineering biology, and unlock its potential for good. To achieve this, we must overcome two key challenges. First, we need the ability to write in the natural language of biology, enabling the rapid and scalable synthesis of entire genomes with precision. Second, we must understand what to write - determining which DNA sequences will generate biological systems that perform the desired functions. Addressing these challenges will allow us to harness the full power of biology to create transformative solutions across health, agriculture, clean energy and more. The Generative Biology Institute commenced operations in 2025, occupying newly renovated bespoke space in the Oxford Science Park. The team will later move to a purpose-made facility in the Oxford Science Park, currently under construction. Once complete, this state-of-the-art facility will include more than 40,000 m² of research laboratory and office space. It will house over 30 groups and up to 600 employees at scale, focused on solving the two critical challenges in making biology engineerable and applying the solutions to addressing the global challenges encapsulated in EIT’s Humane Endeavours. The AI & Robotics Team The AI & Robotics team at EIT brings together AI research, robotics and scientific expertise to make biological matter computable and testable, at scale, and by any scientist. We build generative and predictive models of biological molecules and systems, physics-grounded simulation and design tools, and autonomous laboratories that generate the data these models learn from and test the designs they propose. Project Monera You will be joining the projectMonera, a joint project across the Generative Biology Institute and the AI & Robotics team building multi-modal generative models of whole organisms, starting with Escherichia coli in order to understand and predict an organism's phenotype from its genome and environment and, in time, to design genomes for a desired function. The team works as one integrated computational and experimental group: experimentalists generate genetic variation and quantitative measurements at scale (growth and fitness, transcriptomics, proteomics, metabolomics), the models are trained and validated on that data, and the results shape the next round of experiments and insights. The experimental work is based in GBI's laboratories in the Oxford Science Park, alongside GBI's automation capability and in daily contact with the AI scientists in the AI & Robotics team. Job Summary We are building a joint experimental computational team focussed on building, training and validating multi-modal biological models. The team will: i) generate experimental perturbation and measurement data at scale, ii) build multi-modal biological models and, iii) use the experimental data they generate to train and validate the multi-modal biological models they build. In this role you will: i) perform experimental genome engineering work to generate genetic variation at scale and/or ii) design and implement scalable biological measurement over one or more modalities. Where appropriate the work will leverage the substantial automation capability within the institute. Your work will be performed under the guidance of Jason Chin. You will be part of a single team composed of AI scientists and synthetic biologists working together. We are looking for colleagues with deep expertise in genome engineering and/or quantitative phenotyping of model bacterial species such as Escherichia coli . The role requires the ability and willingness to work as part of a cross-disciplinary team at the interface of computational and wetlab biology. Our team ethos is based on mutual learning, strong peer-to-peer support, and a deep sense of scientific curiosity and ambition. This is your opportunity to be part of cutting-edge research within an institute dedicated to engineering biology at an unprecedented scale. You will be leveraging GBI’s exceptional facilities, sustained funding, and collaborative environment. You will design and execute experiments, contribute to high-impact publications, and play a key role in the training and mentorship of junior researchers and students. Working at the interface of biology, AI, technology, and engineering, you will help shape GBI’s vision to reimagine what’s possible in biology. Key Responsibilities: Design, execute, and troubleshoot experiments, including the development of novel methodologies and adaptation of existing techniques to new applications. In particular, the successful applicant will utilise genome engineering strategies in the lab to produce a diversity of microbial strains as the source of training and validation data in a high throughput fashion. In addition, they will also design and prototype a range of experimental measurement strategies for characterising these strains at scale. Collaborate with other GBI scientists from other groups expert in synthetic biology, automation, bioinformatics, -omics and machine learning, and AI scientists from the AIR institute, as required. Analyse complex datasets using computational and statistical tools, interpreting results in the context of broader research goals. Contribute intellectually to the research direction by identifying opportunities for innovation and refining research questions. Prepare and publish high-quality scientific papers, reports, presentations, and protocols. Present research at national and international conferences, seminars, and internal meetings. Collaborate with multidisciplinary teams within GBI, EIT, and external partners to advance complementary workstreams. Build and maintain research infrastructure, laboratory capabilities, and cutting-edge technologies. Mentor and support junior researchers, including PhD students and research assistants. Translate research findings into commercial or translational opportunities in alignment with EIT’s mission. Identify and pursue opportunities for intellectual property generation and protection. Ensure research activities comply with EIT’s policies, legal requirements, and best scientific practice. This list is not exhaustive and the role holder may be required to undertake additional tasks and duties commensurate with the role. Relevant, Skills and Experience: Completed a PhD in a relevant field (e.g., synthetic biology, computational biology and AI, microbial genomics, cell biology, genomics, robotics and automation, metabolomics, and proteomics.). Track record of delivering ambitious research projects to a high standard. Strong track record in research, ideally in molecular biology, synthetic biology, or related fields. Skilled in data analysis and interpretation; experience with genomic analysis, automation, or computational tools desirable. Proven ability to work independently, think creatively, and solve complex experimental problems. Experience publishing in high-impact journals and presenting at international conferences. Excellent organisational skills with the ability to manage multiple concurrent projects. Strong written and verbal communication skills, with experience collaborating in multidisciplinary teams. Capacity to build and sustain productive collaborations internally and externally. Resilience, adaptability, and enthusiasm for working in a fast-paced, high-growth research environment. Deep scientific curiosity and the drive to run ambitious experiments at scale, which can be used for the training and validating foundation models for the purpose of understanding and predicting an organism's phenotype from its genome and environment. Basic familiarity with machine-learning concepts is welcome (what a model needs from data: coverage of the variable space, controls, replication, consistent metadata). Our Benefits: Annual Bonus Travel Allowance Enhanced sick pay Pension - Employer contribution 7.5%, minimum employee contribution 5% Life Assurance Income Protection Private Medical Insurance as standard for you, your partner and any dependents. Including hospital Cash Plan Employee discounts Electric car scheme Nursery Salary Sacrifice scheme Cycle to Work Scheme Family Planning Neurodiversity support including advise and assessments Coaching & Therapy services Working Together – What It Involves: You must have the right to work permanently in the UK with a willingness to travel as necessary. In certain cases, we can consider sponsorship, and this will be assessed on a case-by-case basis. You will live in, or within easy commuting distance of, Oxford (or be willing to relocate). #J-18808-Ljbffr

At the Ellison Institute of Technology (EIT), we’re on a mission to translate scientific discovery into real world impact. We bring together visionary scientists, technologists, engineers, researchers, educators and innovators to tackle humanity’s greatest challenges in four transformative areas: • Health, Medical Science & Generative Biology, • Food Security & Sustainable Agriculture, • Climate Change & Managing CO₂, • Artificial Intelligence & Robotics This is ambitious work - work that demands curiosity, courage, and a relentless drive to make a difference. At EIT, you’ll join a community built on excellence, innovation, tenacity, trust, and collaboration, where bold ideas become real-world breakthroughs. Together, we push boundaries, embrace complexity, and create solutions to scale ideas from lab to society. Led by Founding Director Jason Chin, the Generative Biology Institute (GBI) at the Ellison Institute of Technology is tackling the key challenges in making biology engineerable, and thereby unlocking the unrivalled power of biology for the benefit of humanity. The vision of the GBI is to lay the foundations for engineering biology, and unlock its potential for good. To achieve this, we must overcome two key challenges. First, we need the ability to write in the natural language of biology, enabling the rapid and scalable synthesis of entire genomes with precision. Second, we must understand what to write – determining which DNA sequences will generate biological systems that perform the desired functions. Addressing these challenges will allow us to harness the full power of biology to create transformative solutions across health, agriculture, clean energy and more. The Generative Biology Institute commenced operations in 2025, occupying newly renovated bespoke space in the Oxford Science Park. The team will later move to a purpose‑made facility in the Oxford Science Park, currently under construction. Once complete, this state‑of‑the‑art facility will include more than 40,000 m² of research laboratory and office space. It will house over 30 groups and up to 600 employees at scale, focused on solving the two critical challenges in making biology engineerable and applying the solutions to addressing the global challenges encapsulated in EIT’s Humane Endeavours. We are seeking ambitious, creative, and highly skilled Postdoctoral Researchers to join the Zuercher Lab at GBI. The Zuercher Lab, led by Principal Investigator Jerome Zuercher, focuses on two interconnected areas, with many projects involving aspects of both topics (Genome synthesis and Genetic Isolation). A direct consequence of the universality of the genetic code is the possibility for genetic information to be transferred between evolutionarily distant species. Such horizontal transfer of genetic information (as opposed to vertical genetic transfer, where information is passed on from an organism to its progeny) is common in nature and has shaped evolution over billions of years. In the context of genetic engineering, however, this type of genetic spillover is highly concerning. Prevention of interference of artificial genetic information with natural biology is critical to allow biotechnological progress to be both safe and ambitious. Furthermore, biotechnology will play a central role in addressing pressing challenges in food security, pharmaceutical development, sustainable fuel sources, and efficient carbon fixation. Thus, essential parts of the economy will increasingly rely on bioproduction facilities harbouring tailor‑made microbes. It is therefore critical that such facilities are extremely reliable. However, due to the universality of the genetic code, engineered organisms are just as susceptible to viral invasion as natural organisms. In fact, a single viral particle that finds its way into a bioproduction facility can force its operational shutdown. Altering the genetic code of a cell provides an opportunity to render natural and synthetic genetic information incompatible. This breakthrough offers a means to protect the environment from genetically engineered organisms and, vice versa, engineered organisms critical for bioproduction from viral invasion. Through concerted efforts in genome recoding and translational engineering, it was possible to create the first organism with a synthetic genetic code. Since this organism “speaks a different language” than organisms found in nature, it is genetically isolated; it can neither give nor receive genetic information from the environment. The lab continues the development of altered genetic codes to increase the safety of biotechnology and aims to rewrite even the most complex biological systems in alternative synthetic genetic codes. Our ability to write DNA has recently expanded to the genomic scale. The possibility of defining every single base in the genome of a cell enables manipulation of the most fundamental cellular properties, such as the genetic code. However, current genome synthesis methods are slow, narrow in scope, and limited in scale. To date, the genomes of only two bacteria have been successfully synthesized. This project aims to develop methodologies to make the synthesis of model organism genomes (i.e. E. coli) more rapid and enable the synthesis of the genomes of non‑model bacteria to broaden the scope of genome synthesis. The ability to routinely synthesize the genomes of a diverse set of organisms will not only allow reprogramming of the genetic code but also facilitate testing of generative genome designs. Ultimately, the combination of microbial genome synthesis and artificial intelligence will enable biological design at the organism scale with implications in bioproduction, human health, agriculture, and beyond. Learn more at jzlab.bio Applications will be reviewed on a rolling basis. In your cover letter, please clearly explain your fit, interest, and relevant experience for joining the group. All applications must be submitted exclusively though the EIT job portal. If you would like to discuss this role in more detail, prior to submitting an application, please contact Jerome Zuercher at . Due to the volume of applications, the review and decision process may take 3–6 months. • Design, execute, and troubleshoot experiments, including the development of novel methodologies and adaptation of existing techniques to new applications., • Analyse complex datasets using computational and statistical tools, interpreting results in the context of broader research goals., • Contribute intellectually to the research direction by identifying opportunities for innovation and refining research questions., • Prepare and publish high-quality scientific papers, reports, presentations, and protocols., • Present research at national and international conferences, seminars, and internal meetings., • Collaborate with multidisciplinary teams within GBI, EIT, and external partners to advance complementary workstreams., • Build and maintain research infrastructure, laboratory capabilities, and cutting‑edge technologies., • Mentor and support junior researchers, including PhD students and research assistants., • Translate research findings into commercial or translational opportunities in alignment with EIT’s mission., • Identify and pursue opportunities for intellectual property generation and protection., • Ensure research activities comply with EIT’s policies, legal requirements, and best scientific practice. This list is not exhaustive and the role holder may be required to undertake additional tasks and duties commensurate with the role. • Completed a PhD in a relevant field (e.g., synthetic biology, computational biology and AI, microbial, plant and human cell biology, genomics, robotics and automation, and nucleic acids chemistry)., • Track record of delivering ambitious research projects to a high standard., • Strong track record in research, ideally in molecular biology, synthetic biology, or related fields., • Skilled in data analysis and interpretation; experience with genomic analysis, automation, or computational tools desirable., • Proven ability to work independently, think creatively, and solve complex experimental problems., • Experience publishing in high‑impact journals and presenting at international conferences., • Excellent organisational skills with the ability to manage multiple concurrent projects., • Strong written and verbal communication skills, with experience collaborating in multidisciplinary teams., • Capacity to build and sustain productive collaborations internally and externally., • Resilience, adaptability, and enthusiasm for working in a fast‑paced, high‑growth research environment., • Salary: Competitive + travel allowance + bonus, • Enhanced holiday pay, • Pension, • Life Assurance, • Income Protection, • Private Medical Insurance, • Hospital Cash Plan, • Therapy Services, • Perk Box, • Electric Car Scheme, • You must be eligible to work in the UK with a willingness to travel as necessary. We are open to sponsoring employment visas for this role; however, sponsorship is not available for all visa types or in all circumstances. Eligibility will be assessed on a case‑by‑case basis., • You must be based in, or within easy commuting distance of, Oxford (or be willing to relocate)., • During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme., • Our Postdoc roles are set up as a 4‑year fixed‑term contract #J-18808-Ljbffr

At the Ellison Institute of Technology (EIT), we’re on a mission to translate scientific discovery into real world impact. We bring together visionary scientists, technologists, engineers, researchers, educators and innovators to tackle humanity’s greatest challenges in four transformative areas: • Health, Medical Science & Generative Biology, • Food Security & Sustainable Agriculture, • Climate Change & Managing CO₂, • Artificial Intelligence & Robotics This is ambitious work - work that demands curiosity, courage, and a relentless drive to make a difference. At EIT, you’ll join a community built on excellence, innovation, tenacity, trust, and collaboration, where bold ideas become real-world breakthroughs. Together, we push boundaries, embrace complexity, and create solutions to scale ideas from lab to society. Welcome to the Generative Biology Institute: Led by Founding Director Jason Chin, the Generative Biology Institute (GBI) at the Ellison Institute of Technology is tackling the key challenges in making biology engineerable, and thereby unlocking the unrivalled power of biology for the benefit of humanity. The vision of the GBI is to lay the foundations for engineering biology, and unlock its potential for good. To achieve this, we must overcome two key challenges. First, we need the ability to write in the natural language of biology, enabling the rapid and scalable synthesis of entire genomes with precision. Second, we must understand what to write - determining which DNA sequences will generate biological systems that perform the desired functions. Addressing these challenges will allow us to harness the full power of biology to create transformative solutions across health, agriculture, clean energy and more. The Generative Biology Institute commenced operations in 2025, occupying newly renovated bespoke space in the Oxford Science Park. The team will later move to a purpose‑made facility in the Oxford Science Park, currently under construction. Once complete, this state‑of‑the‑art facility will include more than 40,000 m² of research laboratory and office space. It will house over 30 groups and up to 600 employees at scale, focused on solving the two critical challenges in making biology engineerable and applying the solutions to addressing the global challenges encapsulated in EIT’s Humane Endeavours. The Zuercher Lab We are seeking ambitious, creative, and highly skilled Postdoctoral Researchers to join the Zuercher Lab at GBI. The Zuercher Lab, led by Principal Investigator Jerome Zuercher, focuses on two interconnected areas, with many projects involving aspects of both topics (Genome synthesis and Genetic Isolation). Genetic Isolation A direct consequence of the universality of the genetic code is the possibility for genetic information to be transferred between evolutionarily distant species. Such horizontal transfer of genetic information (as opposed to vertical genetic transfer, where information is passed on from an organism to its progeny) is common in nature and has shaped evolution over billions of years. In the context of genetic engineering, however, this type of genetic spillover is highly concerning. Prevention of interference of artificial genetic information with natural biology is critical to allow biotechnological progress to be both safe and ambitious. Furthermore, biotechnology will play a central role in addressing pressing challenges in food security, pharmaceutical development, sustainable fuel sources, and efficient carbon fixation. Thus, essential parts of the economy will increasingly rely on bioproduction facilities harbouring tailor‑made microbes. It is therefore critical that such facilities are extremely reliable. However, due to the universality of the genetic code, engineered organisms are just as susceptible to viral invasion as natural organisms. In fact, a single viral particle that finds its way into a bioproduction facility can force its operational shutdown. Altering the genetic code of a cell provides an opportunity to render natural and synthetic genetic information incompatible. This breakthrough offers a means to protect the environment from genetically engineered organisms and, vice versa, engineered organisms critical for bioproduction from viral invasion. Through concerted efforts in genome recoding and translational engineering, it was possible to create the first organism with a synthetic genetic code. Since this organism “speaks a different language” than organisms found in nature, it is genetically isolated; it can neither give nor receive genetic information from the environment. The lab continues the development of altered genetic codes to increase the safety of biotechnology and aims to rewrite even the most complex biological systems in alternative synthetic genetic codes. Genome synthesis Our ability to write DNA has recently expanded to the genomic scale. The possibility of defining every single base in the genome of a cell enables manipulation of the most fundamental cellular properties, such as the genetic code. However, current genome synthesis methods are slow, narrow in scope, and limited in scale. To date, the genomes of only two bacteria have been successfully synthesized. This project aims to develop methodologies to make the synthesis of model organism genomes (i.e. E. coli) more rapid and enable the synthesis of the genomes of non‑model bacteria to broaden the scope of genome synthesis. The ability to routinely synthesize the genomes of a diverse set of organisms will not only allow reprogramming of the genetic code but also facilitate testing of generative genome designs. Ultimately, the combination of microbial genome synthesis and artificial intelligence will enable biological design at the organism scale with implications in bioproduction, human health, agriculture, and beyond. Learn more at jzlab.bio How to Apply Applications will be reviewed on a rolling basis. In your cover letter, please clearly explain your fit, interest, and relevant experience for joining the group. All applications must be submitted exclusively through the EIT job portal. If you would like to discuss this role in more detail, prior to submitting an application, please contact Jerome Zuercher at . Due to the volume of applications, the review and decision process may take 3–6 months. Key Responsibilities: • Design, execute, and troubleshoot experiments, including the development of novel methodologies and adaptation of existing techniques to new applications., • Analyse complex datasets using computational and statistical tools, interpreting results in the context of broader research goals., • Contribute intellectually to the research direction by identifying opportunities for innovation and refining research questions., • Prepare and publish high‑quality scientific papers, reports, presentations, and protocols., • Present research at national and international conferences, seminars, and internal meetings., • Collaborate with multidisciplinary teams within GBI, EIT, and external partners to advance complementary workstreams., • Build and maintain research infrastructure, laboratory capabilities, and cutting‑edge technologies., • Mentor and support junior researchers, including PhD students and research assistants., • Translate research findings into commercial or translational opportunities in alignment with EIT’s mission., • Identify and pursue opportunities for intellectual property generation and protection., • Ensure research activities comply with EIT’s policies, legal requirements, and best scientific practice. This list is not exhaustive and the role holder may be required to undertake additional tasks and duties commensurate with the role. Essential and Desirable Knowledge, Skills and Experience: • Completed a PhD in a relevant field (e.g., synthetic biology, computational biology and AI, microbial, plant and human cell biology, genomics, robotics and automation, and nucleic acids chemistry)., • Track record of delivering ambitious research projects to a high standard., • Strong track record in research, ideally in molecular biology, synthetic biology, or related fields., • Skilled in data analysis and interpretation; experience with genomic analysis, automation, or computational tools desirable., • Proven ability to work independently, think creatively, and solve complex experimental problems., • Experience publishing in high‑impact journals and presenting at international conferences., • Excellent organisational skills with the ability to manage multiple concurrent projects., • Strong written and verbal communication skills, with experience collaborating in multidisciplinary teams., • Capacity to build and sustain productive collaborations internally and externally., • Resilience, adaptability, and enthusiasm for working in a fast‑paced, high‑growth research environment. Our Benefits: • Salary: Competitive + travel allowance + bonus, • Enhanced holiday pay, • Pension, • Life AssuranceIncome Protection, • Private Medical Insurance, • Hospital Cash Plan, • Therapy Services, • Perk Box, • Electric Car Scheme Working Together – What It Involves: • You must be eligible to work in the UK with a willingness to travel as necessary. We are open to sponsoring employment visas for this role; however sponsorship is not available for all visa types or in all circumstances. Eligibility will be assessed on a case‑by‑case basis., • You must be based in, or within easy commuting distance of, Oxford (or be willing to relocate)., • During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme., • Our Postdoc roles are set up as 4 year fixed term contracts #J-18808-Ljbffr

ABOUT ORGANOX: OrganOx is a commercial stage organ technology company dedicated to developing technologies to improve outcomes for patients with acute or chronic organ failure. The company was established as a spin out of the University of Oxford in 2008 and is now part of the Terumo Group. OrganOx is a pioneer in normothermic machine perfusion (NMP). It's flagship platform, the metra®, is available for use in the U.S., Europe, Canada, and Australia. It has been utilized in over 7,000 liver transplants to date to keep donor livers in a metabolically active state outside the body enabling longer preservation times and functional assessment of the organ prior to transplant, leading to an increased number of organs available for transplant. Founded in 1921, Terumo Corporation (TSE:4543) strives to fulfil its mission of “Contributing to Society through Healthcare” by providing a comprehensive range of solutions in the fields of therapeutic procedures, hospital operations, and life sciences in more than 160 countries and regions. Position Summary The Windows Software Manager is responsible for leading the design and development of software at OrganOx, for device-hosted applications and services running on Windows-based platforms, ensuring delivery of robust, high-quality solutions for regulated medical environments. The role combines deep technical expertise developing Graphical User Interfaces (GUI), connectivity solutions and implementing cybersecurity mitigations, with strong leadership of teams, projects and cross-functional stakeholders. Operating with a system-level perspective, the Windows Software Manager takes end-to-end ownership of the application software, driving alignment with quality standards and regulatory compliance requirements. The role also serves as a key technical representative for OrganOx, engaging confidently with external stakeholders including regulatory bodies, partners, and customers. This is an on-site role in Oxford with flexibility. Listed below are the major responsibilities of the role and a brief description of some of the key tasks to be performed. This list is not totally exhaustive. Major Responsibilities Under direction from the Director, Embedded Software Development, the Windows Software Manager will be responsible for: Resource management • Lead and manage a team of Windows software engineers, fostering a high-performance culture of collaboration, continuous improvement, and engineering excellence., • Providing line management, including goal setting, performance reviews, development planning, and ongoing coaching., • Mentor and support engineers in low-level design, debugging, and real-time system development challenges., • Define and maintain an effective team structure, including roles, responsibilities, operating mechanisms, and supporting infrastructure., • Plan and manage resource allocation, including headcount planning, role definition, workload distribution, and optimisation of team utilisation across distributed teams., • Oversee recruitment activities, including identifying hiring needs, interviewing, candidate evaluation, hiring recommendations, onboarding, and probation management., • Maintain visibility of team capabilities (knowledge, skills, and abilities) and develop targeted training and development plans to address gaps and enhance performance., • Facilitate clear and effective communication within the team and across stakeholders, ensuring alignment with wider organisational objectives. Planning • Manage project timelines, resources, and budgets, ensuring projects are delivered on time and within scope., • Guide technical decisions, design reviews., • Ensure robust software integration with cross-functional teams, • Drive Agile or hybrid Software Development Life Cycle (SDLC) practices., • Author and execute a roadmap of developments to improve the Software Engineering function, with emphasis on application-level software., • Financial forecasting and spend tracking against approved department and project budgets. Technical Oversight & Execution • Provide technical leadership for the development of application-level software for Class II and Class III medical devices., • Oversee the full software development lifecycle, including requirements definition, architecture, implementation, testing, and maintenance., • Ensure compliance with applicable regulatory standards and frameworks, including FDA, ISO 13485, IEC 62304, and other relevant safety standards., • Establish and enforce high-quality software engineering practices, including code reviews, architectural governance, and design best practices., • Contribute hands-on expertise in complex or critical technical areas when required., • Drive design principles that support modularity, testability, maintainability, scalability., • Oversee release quality, defect management, and continuous improvement initiatives. Process and tools • SOPs (Standard Operating Procedures) and Work Instructions supporting Software Engineering., • Selection, development, and qualification of Software Engineering tools and systems. Continuous Improvement & Innovation • Stay current with industry trends, emerging technologies, and best practices in software and medical device development., • Continuously improve development processes, tools, and engineering practices., • Drive innovation in IoMT-enabled medical devices, ensuring seamless integration with cloud and connected systems., • Introduce automation, performance optimisation, and data-driven analytics., • Oversee and approve Software Engineering Design History Files (DHF)., • Adhere to the letter and spirit of OrganOx’s Code of Conduct and all other company policies Requirements Skills & Experience • Proven track record in the development, release, and maintenance of Class II/III medical device software or similarly safety-critical systems., • Deep understanding of the Software Development Life Cycle (SDLC), including agile methodologies and comprehensive testing strategies (unit, integration)., • Proven understanding of edge-to-cloud architectures., • Solid experience designing OTA update mechanisms, including safe update strategies (e.g. rollback, validation, compatibility), • Strong working knowledge and application of messaging technologies (e.g. Azure IoT Hub, MQTT, AMQP)., • Solid expertise in C#, C++ and .net framework., • Familiar with Real-Time Operating System (RTOS) concepts (task scheduling, interrupts, concurrency) and Board Support Package (BSP)., • Familiarity with Unified Modelling Language (UML) and object-oriented design principles., • Demonstrated ability to build, lead, and develop high-performing engineering teams with a collaborative leadership approach., • Strong systems-thinking capability, with the ability to view and optimise across software layers under real-world constraints., • Proven problem-solving skills, including proactive identification and mitigation of technical risks., • Experience with model-based and model-driven development, and simulation tools to accelerate development and testing. Strong expertise in IoMT technologies and cloud-based system integration., • Comprehensive knowledge of regulatory standards and frameworks, including IEC 62304, ISO 14971, FDA guidance, ISO 13485 and ISO 62366., • Ability to tailor compliance approaches while maintaining focus on risk, cybersecurity, scalability, maintainability and reliability., • Proven experience managing external technical partners and ensuring quality deliverables across the full product lifecycle., • Track record of driving process improvements to enhance efficiency, compliance, and product quality., • Skilled in both developing innovative solutions and maintaining existing products in line with QMS (Quality Management System) and industry standards., • Highly effective in applying problem-solving techniques (e.g. brainstorming, 5-whys, fishbone), supported by demonstrable structured and rigorous approach to define activities and achieve tangible deliverables with limited supervision, • An effective communicator, who readily engages in a timely and proactive manner, • Passion for innovation and commitment to developing medical devices that improve patient outcomes. Qualifications • Bachelor’s or Master’s degree in Computer Science, Electrical Engineering, or a related field. Benefits At OrganOx, we value innovation, evidence, integrity, teamwork, respect, and passion. We offer competitive compensation and comprehensive benefits, including healthcare and retirement plans. We support work-life balance and provide opportunities for ongoing professional development. We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion or belief, sex, sexual orientation race, or any other characteristics protected by law. #J-18808-Ljbffr

Oxfida (formerly Aioi R&D Lab - Oxford) is an AI R&D company based in Oxford, on a mission to harness AI to understand, predict, and manage risk, helping build a safer, more resilient society. We sit at the intersection of academia and industry, working with Oxford's professors and researchers alongside commercial partners, and combining that expertise with real-world risk data at global scale to turn frontier research into AI that actually ships rather than just gets published. Our work spans AI for insurance underwriting and claims, AI risk governance, privacy-preserving technologies for agentic AI, and quantum optimisation, alongside partnership projects on nature and supply chains and the emerging challenges nobody's solved yet. We build AI products and solutions for insurers, businesses, and public-sector organisations worldwide, and run innovative research projects that push these technologies further, helping people make better decisions in an uncertain world. Trusted AI. Built in Oxford. CODAS is our multi-year sovereign AI research and development programme, bringing together specialist teams and external partners to advance privacy preserving AI, secure AI platforms and new commercial applications. We're looking for dynamic, driven professionals to help us deliver this ambitious programme. You'll need strong credentials, a proactive approach and the confidence to bring clarity and momentum to complex, evolving work. As the CODAS Project Manager, you will coordinate the day to day delivery of the programme across its four interconnected tracks. Working closely with the Programme Director, Track Leads, technical and research specialists, and programme support functions, you will bring structure, pace and discipline to delivery. You will help maintain the integrated programme plan, coordinate milestones and dependencies, manage programme track risks and actions, and ensure stakeholders have a clear and reliable view of progress. • The day to day delivery of CODAS is coordinated effectively across four interconnected tracks, with agreed programme outcomes, milestones and deliverables translated into clear plans and managed effectively through to completion., • The integrated programme plan brings together track level milestones, deliverables, dependencies, resource requirements and target dates in one reliable view., • Programme risks, issues, assumptions and dependencies are identified, managed and escalated promptly through the programme RAID log., • Stakeholders across technical, research, commercial and operational audiences have a clear and reliable view of delivery progress through regular communications and reporting., • Programme governance and change control, owned by the Programme Manager, are supported through track-level coordination and delivery input, enabling effective decision-making by the Programme Director and the Programme Steering Committee., • Cross track dependencies and blockers are coordinated, with clear actions, owners and resolution dates, and material concerns escalated promptly., • 3+ years' experience managing complex technical projects or programmes, ideally within a technology, data, AI or research and development environment., • Proven experience managing delivery end to end, including mobilisation, planning, execution, governance, change control, and delivery reviews., • Experience developing and maintaining integrated delivery plans across multiple workstreams, including milestones, dependencies, resources and delivery forecasts., • Experience managing timelines, budgets, resource requirements, RAID logs, actions, decisions and stakeholder communications., • Comfortable working across both defined contractual deliverables and more exploratory research or innovation activity where plans may evolve as the work progresses., • Experience coordinating delivery across cross functional teams, working closely with technical leads, researchers, programme leadership and specialist functions such as Finance, Legal, Data Protection and Operations., • Experience establishing and supporting effective programme governance, including delivery reviews, senior reporting and steering forums., • Excellent stakeholder management skills, with the confidence to communicate clearly with senior internal stakeholders, technical teams, researchers and external programme partners., • Able to coordinate and influence delivery without direct line management authority, constructively challenging progress and escalating concerns when required., • Experience delivering projects or programmes within insurance, financial services or another regulated industry., • Experience working on publicly funded, grant funded, consortium or multi partner programmes with formal reporting, governance or evidence requirements., • Experience delivering AI, machine learning, data platform, privacy, cyber security or other research and development initiatives., • Familiarity with formal programme reporting and assurance requirements, particularly where delivery progress must align with financial, contractual or audit evidence., • Experience contributing to or developing project management processes, templates, playbooks and knowledge management systems, such as Confluence based resources., • Experience using collaborative planning and delivery tools such as Confluence, Jira, Productive, GitLab or equivalent., • Exposure to structured project management frameworks such as PRINCE2, APM, PMP, Agile, Scrum or equivalent., • Experience improving or automating programme management processes and reporting., • A recognised project management qualification (e.g. PRINCE2, APM PMQ, PMP) is desirable but not essential. We're all about helping you grow, with plenty of support to develop in your current role whilst also creating opportunities to explore new ones and advance your career. We realise that we need to be a good fit for you above all else – so here’s what you can enjoy about AND-E: • Recognised as the Best Large Insurance Employer: We are proud to have been named the Best Large Insurance Employer for 2023 at the prestigious British Insurance Awards., • Unmatched Work-Life Balance., • Competitive Salaries and Benefits Package: We offer competitive salaries that recognise your skills and expertise. We champion choice, flexibility, and balance in both work and home life. Our commitment to diversity, equity, and inclusion ensures everyone feels valued and supported - including embracing neurodiversity and providing the tools needed to thrive. We like to think our benefits package is one of the best, focusing on colleagues' health, wealth, and lifestyle. We offer: • Up to 28 Days annual leave with the option to buy/sell up to 5 days holiday, • Healix Private Medical Insurance Options, • 3 x Annual Salary Life Assurance, • A range of health, wellbeing, and financial support benefits, including money back on health expenses, Employee Assistance Programme, Flu Jab voucher, Virtual GP service, and driving lessons for you and your family., • Additional perks such as a pension advisory service, family-friendly policies, season ticket loan, cycle scheme, and financial flexibility through Wagestream. Subject to company performance and completion of probation Aioi Nissay Dowa Europe is committed to promoting equal opportunities in employment. Employees and job applicants will receive equal treatment regardless of age, disability, gender reassignment, marital or civil partner status, pregnancy or maternity, race, colour, nationality, ethnic or national origin, religion or belief, sex or sexual orientation (Protected Characteristics) At AND-E, equal opportunity is more than a policy-its a promise. We welcome applications from all individuals regardless of age, disability, gender identity, marital status, pregnancy, race, religion, sexual orientation, or any other protected characteristic. Reasonable adjustments: If you require any adjustments to support you during our recruitment process, please let us know. We’re committed to making the process accessible and are happy to help #J-18808-Ljbffr

Aioi Nissay Dowa Europe seeks a CODAS Project Manager in Oxford to coordinate day-to-day delivery of a multi-track synthetic programme. You will work with the Programme Director, track leads, researchers and operations to maintain an integrated plan, manage risks and keep stakeholders informed of progress. You will guide governance, support decision-making, and ensure delivery milestones align with contractual and research goals, across finance, legal and data protection teams. #J-18808-Ljbffr

Design Office Manager Technical Director The Design Office Manager is responsible for leading and managing the design office function, ensuring the efficient delivery of engineering and design projects to agreed quality, cost, and schedule targets. The role provides technical leadership, resource management and continuous improvement across all design activities while ensuring compliance with applicable standards, regulations, and company procedures. • Lead, develop, and manage the design office team., • Establish clear objectives, priorities, and performance expectations for team members., • Support recruitment, onboarding, training, and succession planning activities., • Foster a culture of collaboration, innovation, accountability, and continuous improvement., • Conduct regular performance reviews and support continuous professional development., • Plan, coordinate, and oversee all design activities to ensure successful project execution., • Manage mechanical design resources and workload allocation across multiple projects., • Ensure design outputs meet customer requirements, technical specifications, and regulatory standards., • Review and approve mechanical designs, drawings and technical documentation., • Monitor design progress and resolve technical issues that may impact project delivery., • Work closely with project managers to ensure engineering deliverables are completed on time and within budget., • Develop and maintain project schedules related to design activities., • Identify project risks and implement mitigation plans., • Provide accurate estimates for mechanical design effort, resources, and timelines., • Support customer meetings, design reviews, and technical presentations as required., • Ensure compliance with relevant engineering standards, industry regulations, and company quality management systems., • Maintain design control work flows and document management processes., • Lead design reviews, audits, and verification activities., • Drive lessons learned and continuous improvement initiatives., • Ensure all design records are maintained and controlled appropriately., • Develop and implement best practices for engineering and design processes., • Promote the use of modern design tools, digital engineering methods, and automation technologies., • Identify opportunities to improve efficiency, quality, and productivity within the design office., • Support the implementation of new engineering systems, software, and procedures., • Act as the primary interface between engineering, project management, operations, manufacturing and procurement., • Ensure effective communication of design status and resource requirements., • Build strong relationships with customers, suppliers, and external engineering partners., • Support business development activities by providing technical expertise and proposals input., • On-time delivery of engineering and design deliverables., • Design quality and reduction of engineering errors., • Resource utilisation and workload management., • Customer satisfaction., • Compliance with quality and regulatory requirements., • Team engagement, development, and retention., • Continuous improvement implementation and efficiency gains., • Degree / HND in Engineering or a related discipline., • Significant experience in engineering design and project delivery., • Strong understanding of engineering design processes., • 3 years' experience with CAD (preferably SolidWorks)., • Proven ability to manage multiple projects and competing priorities., • Experience within process related industries such glass, steel, aluminium etc., • Experience with document management systems, EPDM or Vault., • Strong leadership and people management skills., • Excellent communication and stakeholder management abilities., • Strategic thinking and problem-solving capability., • Commercial awareness and budget management., • Strong planning and organisational skills., • Attention to detail and commitment to quality., • Ability to motivate and develop high-performing teams., • Proficiency in engineering software and Microsoft Office applications., • Office-based with occasional travel to customer sites, suppliers, and manufacturing facilities., • May require flexibility to support project deadlines and business priorities. An effective Design Office Manager combines strong technical engineering knowledge with leadership capability, ensuring that engineering teams deliver high-quality, compliant, and innovative designs while meeting business objectives for safety, quality, cost, and delivery. #J-18808-Ljbffr

Join us in our mission to commercialize fusion energy. About Type One Energy: Type One Energy Group is mission‑driven to provide sustainable, affordable fusion power to the world. Established in 2019 and venture‑backed in 2023, the company is led by a team of globally recognized fusion scientists with a strong track record of building state‑of‑the‑art stellarator fusion machines, together with veteran business leaders experienced in scaling companies and commercializing energy technologies. Location: Knoxville (TN) or Oxford (UK) Salary: Highly Competitive Plus Benefits Contract: Permanent, full time Reporting to: Senior Director of Nuclear and Fuel Cycle Type One Energy is seeking a highly motivated Tritium Engineer to support the development of the Infinity Two Fusion Pilot Plant (FPP) Tritium Plant and associated technology demonstration facilities. This role combines process engineering, process modelling, systems engineering, technology development, and program delivery responsibilities. The successful candidate will support the design, modelling, integration, testing, and maturation of tritium fuel cycle systems required for the deployment of Infinity Two and future commercial stellarator power plants. The role will contribute to the development of tritium extraction, processing, storage, isotope separation, fuel clean‑up, detritiation, fuel delivery, and tritium accountancy systems. In parallel, the successful candidate will support the development of technology demonstrators and experimental facilities used to retire technical risk and increase the technology readiness of key fuel cycle systems prior to FPP deployment. The Tritium Engineer will work closely with the wider Tritium Plant organization, systems engineering teams, safety specialists, physics teams, external laboratories, industrial partners, and suppliers to deliver practical engineering solutions supporting the commercialization of fusion energy. The successful candidate will be expected to balance engineering design, process modelling, technology development, and program delivery activities while acting as a key interface between the Tritium Plant organization and external technology partners. • Support the design, development, integration, and deployment of tritium fuel cycle systems for Infinity Two and associated technology demonstrators., • Develop process engineering deliverables including Process Flow Diagrams (PFDs), Piping & Instrumentation Diagrams (P&IDs), engineering specifications, operating philosophies, equipment sizing calculations, and system design documentation., • Develop and maintain process models of tritium fuel cycle systems using engineering simulation tools such as Aspen Plus, Aspen HYSYS, MATLAB, Python, COMSOL, gPROMS, or equivalent platforms., • Perform process engineering analyses including mass and energy balances, process inventories, equipment performance assessments, process optimization studies, and design trade‑off evaluations., • Support the development of plant‑wide fuel cycle models, tritium accountancy methodologies, digital engineering tools, and digital twin capabilities., • Act as a system engineer for assigned fuel cycle subsystems, supporting progression through Conceptual, Preliminary, and Detailed Design phases., • Identify technology gaps, technical risks, and development opportunities and support maturation of fuel cycle technologies through experimental programmes, technology demonstrators, and research and development activities., • Support commissioning, testing, operation, and analysis of prototype facilities and technology demonstration systems, ensuring lessons learned are incorporated into future plant designs., • Work collaboratively with Tritium Scientists, Fuel Cycle Modelers, Systems Engineers, Safety Engineers, and Design Engineers to develop integrated fuel cycle solutions and support long‑term fuel cycle architecture development., • Develop technical scopes of work, specifications, and engineering requirements for suppliers, contractors, and development partners, and support technical oversight of contracted activities., • Review technical deliverables, monitor progress against program milestones, and support project planning, cost estimation, schedule management, and risk mitigation activities., • Act as a technical interface with universities, national laboratories, industrial partners, suppliers, and regulatory stakeholders to support technology development and program execution., • Support hazard assessments, safety analyses, tritium inventory evaluations, and development of operating procedures to ensure compliance with applicable nuclear, industrial, and quality standards. Bachelor's, Master's, or PhD degree in Chemical Engineering, Process Engineering, Nuclear Engineering, Mechanical Engineering, Physics, Chemistry, Materials Science, or related discipline. • Strong understanding of thermodynamics, fluid mechanics, heat transfer, mass transfer, process design, process safety, process control fundamentals., • Experience developing engineering calculations and process simulations., • Experience using process modelling tools such as Aspen Plus, Aspen HYSYS, MATLAB, Python, COMSOL, gPROMS, or equivalent platforms., • Strong analytical and problem‑solving capabilities., • Excellent communication and stakeholder engagement skills., • Ability to work effectively within multidisciplinary engineering teams., • Experience with fusion fuel cycles, tritium systems, hydrogen technologies, isotope separation systems, or advanced nuclear technologies., • Experience designing, commissioning, or operating industrial process plants., • Knowledge of tritium processing technologies, metal hydride systems, getter beds, cryogenic systems, vacuum systems, gas handling systems, catalytic reactors, permeators, or detritiation systems., • Experience with tritium transport modelling tools such as TMAP, FESTIM, or equivalent., • Familiarity with nuclear safety requirements, regulatory frameworks, and design assurance processes., • Experience managing external suppliers, technical contracts, or collaborative development programs., • Chartered Engineer status or progress toward professional registration., • Basic salary and yearly bonus., • Hybrid work policy., • Stock options., • Relocation assistance., • Insurance plans., • Retirement options., • And many more voluntary benefits. Type One Energy is an equal opportunity employer. We value diversity, searching for the best new ideas and remaining open to unique perspectives. Therefore, all qualified applicants will receive consideration for employment independent of race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, age, or any other characteristics protected by applicable federal, state, or local laws. #J-18808-Ljbffr

At Bloom Energy, our vision for a world powered by clean, reliable, and affordable energy is more than just a dream-we're making it reality. For over two decades, we've been at the forefront of the global energy transition, pioneering solutions that empower critical industries to thrive in a rapidly digitizing, energy-intensive world. From revolutionizing power for AI-driven data centers to ensuring resilience for hospitals, electric grids, manufacturing facilities, and utilities, our solid oxide fuel cell (SOFC) and solid oxide electrolyzer (SOEC) technologies are redefining what's possible by delivering energy abundance for all. With more than 30,000 fuel cell modules deployed worldwide, we are the trusted partner for Fortune 100 companies and innovators alike. Our cutting-edge solutions enable unparalleled "time-to-power" capabilities, reliability, and sustainability, ensuring our customers remain ahead in a world where soaring energy demand and intensifying energy scarcity are rapidly becoming the new norm. At Bloom, we thrive on collaboration, bold thinking, and relentless innovation. We believe that, together, we can create a brighter, more sustainable future while tackling the most pressing challenges of the 21st century. We are looking for a Senior Staff Electrical Engineer, NPI, to join our team in one of today's most exciting technologies. This role will report to Director, Development Engineering, and based in Newark, DE. This is a fully on-site, in office role 5 days a week. • Manage new NPI Project transfers to Bloom Manufacturing and CM's., • Ability to communicate clearly & professionally within the team and also with external vendors., • Develop interconnect wiring diagrams/schematics, wire harness drawings, and test procedures., • Ability to lead electrical team., • Failure analysis of electrical components and preventative or corrective action., • Panel layout and prototyping., • Develop Work Instructions., • Develop, and/or work with suppliers to generate test requirements, test fixtures and test software., • Develop and manage BOMs, ECNs, Deviations., • Work within the development team to ensure design for manufacturability., • Develop test equipment from concept to commissioning., • Train manufacturing personnel on test process, test equipment, and test software., • 8+ years experience in Electrical Engineering or New Product Introduction., • The candidate will have worked in oil and gas, energy and power, pharmaceutical production, chemical processing, large capital equipment, or related industry., • Knowledge of fuel cell systems is a plus but is not required, • Experience developing schematics and wire harness CAD (using AutoCAD), • Ability to independently manage projects, • Experience in rapid scale up of a new products., • Understanding of analog and digital circuits, power devices, magnetics, control systems, switchgear, test equipment and instrumentation, • Hands-on experience testing and troubleshooting high power, high voltage equipment in a laboratory environment, • Experienced in development of test equipment which include electro-mechanical assemblies (e.g.: mass & air flow sensors, DC-DC converters), • Excellent hands-on bench/lab skills working with electrical components (PCB, high voltage components, wiring interconnects, and digital/analog I/O), • Strong written, verbal, and interpersonal communication skills, • Ability to work independently in a fast paced start up environment, • BS or MS in Electrical Engineering or related discipline, • Knowledge of Mechanical Assemblies a plus. Bloom Energy is an equal opportunity employer and makes employment decisions on the basis of merit. We are committed to compliance with all applicable laws providing equal employment opportunities. All qualified applicants, will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability. Bloom Energy makes reasonable accommodations, consistent with applicable laws, for the known physical or mental limitations of an otherwise qualified applicant or employee with a disability, who can perform the essential job functions, unless undue hardship would result. Bloom Energy is committed to fair and equitable compensation practices. The total compensation for this position includes standard company benefits and is based on various factors including, but not limited to, relevant skills and experience. #BEI2024 Salary Ranges: $147,600.00 - $212,400.00 Bloom Energy's mission is to make clean, reliable energy affordable for everyone in the world. With roots in NASA's Mars Program, the company's founder, chairman, and Chief Executive Officer, Dr. K.R. Sridhar, developed an innovative fuel cell technology that is shifting the energy paradigm and redefining the electric power market. The Bloom Energy Server is a distributed electric power solution built for the digital age and capable of delivering highly reliable, uninterrupted, 24x7 constant power that is also clean and sustainable. Bloom's unique on-site power generation systems are among the most efficient on the planet, providing significantly reduced operating costs and producing dramatically lower greenhouse gas emissions. By generating power where it is consumed, Bloom Energy offers increased electrical reliability and improved energy security, providing a clear path to energy independence. Some of the largest companies in the world trust Bloom Energy to provide their businesses with clean, reliable and resilient energy. Bloom's customers include many Fortune 100 companies and leaders in manufacturing, data centers, healthcare, retail, higher education, utilities, and other industries. The company, headquartered in San Jose, California, is growing quickly and looking to add to its dynamic team. Stay up to date with Bloom Energy through our social channels. #J-18808-Ljbffr

Senior Finance Manager - 12-Month Maternity Cover We're looking for an experienced Senior Finance Manager to join Ryze Power in Oxford on a 12-month maternity cover, owning month-end, VAT, audit and cash forecasting for HydraB's energy transition business. If you've seen it before, take pride in a clean balance sheet and are happy to take ownership and run with it, this one's for you. The UK's fleets are going zero-emission, and they need the energy to get there. Ryze Power provides it - supplying hydrogen, building EV charging infrastructure and delivering energy services for commercial fleet, industrial and public sector customers across the UK. From hydrogen bought and sold to infrastructure projects delivered on the ground, Ryze is where the transition to zero-emission transport becomes real. As part of HydraB Group, alongside businesses building the vehicles and hydrogen infrastructure behind that shift, Ryze brings it all together for the customer. Finance that keeps pace with that, with no surprises. This role owns that. This is a hands-on, individual contributor role covering Ryze Power's full reporting cycle - month-end close, balance sheet reconciliations, quarterly VAT, audit and cash flow forecasting. Reporting to the Finance Director, you'll own Ryze Power's results and sub-ledgers in Sage Intacct, while Group Finance manages consolidation and treasury. You'll work closely with Ryze's operations and sales teams, Group Finance and Legal. Support is there when you need it, but this role needs someone who can pick things up quickly and run with it from day one. It's a full-time role, based fully on-site in Oxford, 5 days a week. • Lead the monthly, quarterly and annual reporting cycle, producing accurate and timely management accounts, • Own month-end close and balance sheet reconciliations, keeping the control environment strong, • Prepare quarterly VAT returns and manage other statutory and tax filings, • Coordinate the external audit - auditor queries and year-end financial statements, • Manage cash flow forecasting and liquidity planning, working with Group Finance on treasury, • Get to grips with the commercials of the business - stock, fixed assets, project costs and revenue, and hydrogen bought and sold, • Keep Ryze Power's sub-ledgers and intercompany balances accurate and reconciled ahead of Group consolidation, • Oversee invoicing, collections, credit control and supplier payments to keep working capital under control, • Ensure compliance with FRS 102, the Companies Act and Group accounting policies, including fixed asset accounting and capitalisation, • Spot and deliver improvements to finance processes, controls and reporting, • Are ACA, ACCA or CIMA qualified with 5+ years' post-qualification experience, including time as a Finance Manager or similar, • Have owned month-end close, balance sheet reconciliations, VAT and audit hands-on, • Know UK GAAP and FRS 102 well, and have worked in a group structure with intercompany and consolidation reporting, • Have experience in a growing SME, engineering, manufacturing or project-based environment, • Have advanced Excel skills and a high level of accuracy, • Are a natural problem solver who picks things up quickly and can run with it without close supervision, • Are proactive and keep people in the loop - no surprises, • Build good relationships with finance and non-finance colleagues, and can explain the numbers clearly, • Sage Intacct experience, or a similar cloud ERP, • Experience in energy, hydrogen or infrastructure project accounting, • Pension - up to 8% employer contribution, • Private medical & dental, • 25 days holiday + bank holidays, with buy & sell flexibility, • Life assurance - 4x basic salary, • Income protection, • Electric car salary sacrifice scheme, • Cycle to Work scheme, • Critical illness cover, • Employee referral bonus, • Employee Assistance Programme - 24/7, 365 days, • Retail discounts & cashback via Fizz Benefits, • Eyecare vouchers - Specsavers Ryze Power is part of HydraB Group, pioneering the UK's transition to net zero energy and transport - building the hydrogen and electric infrastructure that gets the sector to scale. #J-18808-Ljbffr

Job Description Location: Wallingford, Oxfordshire, UK Working Pattern: Full-time, 37.5 hours per week, primarily site-based with flexibility where business needs allow. Occasional travel to other laboratory locations may be required. At Fugro, we unlock insights from the Earth to help our clients design, build and operate their assets safely, sustainably and efficiently. As our Laboratory Programme Lead, you'll play a pivotal role in ensuring the successful delivery of laboratory testing programmes that support major infrastructure, energy and environmental projects around the world. Reporting to the Regional Director/Laboratory Manager, you'll lead a team of programme professionals, drive operational excellence and ensure that complex testing schedules are delivered safely, efficiently and to the highest quality standards. This is an exciting opportunity for a collaborative leader who enjoys bringing people, processes and data together to achieve outstanding results in a fast-paced and purpose-driven environment. Your role and responsibilities: • Lead and develop the Laboratory Programme Management team, creating an inclusive, high-performing environment where people can grow, collaborate and succeed., • Own the laboratory planning and programme management framework, ensuring effective governance, resource planning and schedule control across testing programmes., • Provide oversight of laboratory testing schedules, proactively managing risks, dependencies and delivery challenges to improve predictability and on-time performance., • Act as the key escalation point for programme issues, balancing quality, cost, timelines and stakeholder expectations to achieve the best outcomes., • Build trusted relationships with clients, project teams and laboratory stakeholders, ensuring clear communication and excellent service throughout programme delivery., • Support commercial activities including tenders, proposals, programme financial administration and invoicing, helping to deliver value for both clients and the business., • Drive continuous improvement by monitoring programme performance, analysing KPIs and implementing smarter ways of working across the laboratory function. What you'll need to thrive in this role: Essential: • Degree-level qualification, or equivalent professional experience, in programme management, project management or a related discipline., • Demonstrable experience leading a laboratory programme or commercial laboratory operation, with accountability for end-to-end commercial coordination, client success, profitability, and the delivery of predictable, client-focused laboratory services., • Proven experience leading project delivery within a complex, high-throughput or regulated environment., • Experience managing and developing teams, with a track record of driving performance, workforce planning and continuous improvement., • Strong planning, stakeholder management and problem-solving skills, with the ability to make informed decisions in a dynamic operational environment., • Excellent communication skills and confidence working with clients, operational teams and senior stakeholders. Desirable: • Experience working within an ISO 17025 accredited laboratory or similar regulated environment., • APM PMQ, PMI PMP or equivalent project/programme management certification., • Knowledge of geotechnical, geophysical or related laboratory operations. About Us Do you want to join our Geo-data revolution? Fugro's global reach and unique know-how will put the world at your fingertips. Our love of exploration and technical expertise help us to provide our clients with invaluable insights. We source and make sense of the most relevant Geo-data for their needs, so they can design, build and operate their assets more safely, sustainably and efficiently. But we’re always looking for new talent to take the next step with us. For bright minds who enjoy meaningful work and want to push our pioneering spirit further. For individuals who can take the initiative but work well within a team. Fugro provides a positive work environment as well as projects that will satisfy the most curious minds. We also offer great opportunities to stretch and develop yourself. By giving you the freedom to grow faster, we think you'll be able to do what you do best, better. Which should help us to find fresh ways to get to know the earth better. We encourage you to be yourself at Fugro. So, bring your energy and enthusiasm, your keen eye and can-do attitude. But bring your questions and opinions too. Because to be the world’s leading Geo-data specialist, we need the strength in depth that comes from a diverse, driven team. At Fugro, our people are our superpower. Their variety of viewpoints, experiences, knowledge and talents give us collective strength. Distinctive beliefs and diverse backgrounds are therefore welcome, but discrimination, harassment, inappropriate behaviour and unfair treatment are not. Everybody is to be well-supported and treated fairly. And everyone must be valued and have their voice heard. Crucially, we believe that getting this right brings a sense of belonging, of safety and acceptance, that makes us feel more connected to Fugro’s purpose ‘together we create a safe and liveable world’ – and to each other. Benefits of joining our team • Extensive career & training opportunities both nationally and internationally., • Contributory pension scheme, • Private medical insurance, • Health cash plan, • Group life assurance, • Group income protection, • Electric car scheme, • Cycle to work scheme, • Discounted gym membership, • Discounts platform, • The Fugro Card (pre-paid virtual visa card, which earns cash back automatically when money is spent at any participating retailers), • Enhanced maternity and paternity pay, • Long service awards, • Fugro values awards, • Employee referral bonus scheme #J-18808-Ljbffr

WSP UK is seeking a highly capable Technical Director to lead major groundwater and water resources projects within the Catchment Science team. You will direct modelling, EIA and water quality work, and mentor hydrogeologists while shaping project delivery across the UK and beyond. The role offers progression, strong client leadership, and a hybrid-working environment with two days at home. You will collaborate across disciplines and with international colleagues to deliver integrated outcomes #J-18808-Ljbffr

Research Director Oxford, UK | Biotechnology | RNA Technologies | Scientific Leadership Salary: £120,000 - £150,000 + Bonus + Equity Are you an experienced research leader looking to drive scientific innovation and build high-performing teams within a fast-growing biotechnology company? Proclinical is partnering with an exciting and well-funded biotechnology organisation developing next-generation RNA-based technologies. As part of its continued growth, the company is seeking a Research Director to lead laboratory research operations, develop scientific talent, and deliver ambitious research programmes at the forefront of biotechnology innovation. This is a rare opportunity to play a central leadership role within a highly collaborative and entrepreneurial environment where scientific excellence, operational rigour and team development are equally valued. The Opportunity Reporting directly to the CSO, the Research Director will oversee a multidisciplinary group of scientists and laboratory professionals, ensuring that research objectives are delivered effectively, efficiently and to the highest scientific standards. The successful candidate will combine strong scientific expertise with exceptional leadership skills, bringing experience of managing research teams, building laboratory capabilities and driving programme delivery within industry. Key Responsibilities • Lead, mentor and develop a multidisciplinary research team, • Oversee day-to-day laboratory research activities and operational planning, • Drive delivery of scientific programmes against defined objectives and milestones, • Create a high-performance culture focused on collaboration, accountability and innovation, • Manage research resources, budgets, equipment and external partnerships, • Build and optimise laboratory processes, workflows and operating procedures, • Support recruitment, onboarding and development of scientific talent, • Ensure compliance with laboratory quality, safety and documentation standards, • Collaborate with senior leadership to translate strategic priorities into executable research plans, • Identify risks, remove barriers and enable efficient programme execution About You: • Significant experience leading scientific or research teams within biotechnology, life sciences or related sectors, • A strong track record of people leadership, coaching and team development, • Experience delivering complex research programmes within commercially focused organisations, • Scientific expertise in areas such as molecular biology, RNA biology, synthetic biology, biotechnology, microbiology or related disciplines, • Experience managing laboratory operations, resource allocation and project prioritisation, • A passion for building high-performing teams and research organisations, • Excellent communication and stakeholder management skills, • The ability to thrive in a fast-paced, growth-oriented environment Desirable Experience Experience in one or more of the following areas would be advantageous: • mRNA therapeutics, • RNA technologies, • Cell and gene therapy, • Synthetic biology, • Bioprocess development, • High-throughput biology platforms, • Laboratory automation, • GxP environments and quality systems, • Venture-backed biotechnology companies, • Research scale-up environments What's on Offer? • Opportunity to lead a growing research function within an innovative biotechnology company, • Direct influence on scientific strategy, research delivery and team growth, • Highly visible leadership role with significant organisational impact, • Exposure to cutting-edge RNA and biotechnology innovation, • Excellent career development opportunities, • Competitive salary, bonus and benefits package #J-18808-Ljbffr

Bennett & Game Recruitment Ltd. is seeking an experienced Associate Architect or Director to lead delivery across Healthcare, Education, Defence, Heritage and Commercial schemes. The role blends project leadership with business development, client relations and a pathway toward equity partnership. The role involves overseeing a varied portfolio, from £1m-£2m schemes up to £10m, providing strategic direction and senior input on delivery, coordination and problem solving. #J-18808-Ljbffr

Habitat Energy is a fast growing technology company focussed on the physical and financial optimisation of energy storage and renewable generation assets globally through complex models and trading. By maximising the returns from these assets we aim to drive investment in renewable energy and accelerate the transition to a low carbon world. Our rapidly growing team of 130+ people in Austin, TX, Oxford, UK, and Melbourne, Australia brings together exceptionally talented and passionate people in the domains of energy trading, data science, software engineering and renewable energy management. We are seeking a Senior Project Manager for our Operations team in Oxford to manage contracted battery storage projects from execution through to initial trading revenue, maintaining full lifecycle ownership. As the central interface, you will coordinate clients, contractors, and internal teams to resolve divergent interests, tracking milestones and managing risks to ensure assets are fully registered, configured, and commissioned for immediate market participation. You will independently manage a sophisticated GB asset portfolio while driving continuous improvement of onboarding procedures, plans, and templates to enhance future integration efficiency. This role also includes Client Account Management to identify growth opportunities with current clients. Your responsibilities will include: Comprehensive End-to-End Management of Asset Onboarding and Offboarding Processes: • Serve as the primary external representative and point of contact upon contract execution., • Ensure onboarding procedures adhere to the highest standards., • Coordinate internal and external stakeholders to achieve alignment with Habitat and industry timelines., • Ensure assets are integrated or decommissioned without attributable delays., • Lead effective risk and issue management, structured planning, and transparent communication across all departments. Responsible for the implementation, maintenance and proactive continuous improvement of all Asset Onboarding Processes and associated Procedures: • Develop procedures and plans to support the onboarding and offboarding of all UK-contracted clients., • Deliver onboarding processes that meet best-in-class standards., • Update documentation to align with the latest requirements and industry best practices., • Collaborate with Software, Trading, and Operations teams to update procedures for new services or markets. Advance our Asset Monitoring and Control Capabilities: • Drive continuous improvement of the “control system” to enhance asset monitoring capabilities., • Collaborate with the Software team to acquire insights from systems integrators., • Apply key findings to new sites and internal initiatives., • Support the Operations team in diagnosing and implementing control system refinements., • Respond to operational challenges or enable entry into new markets and services. Report and present Onboarding Objectives: • Track specified onboarding metrics and report on progress in each area., • Identify opportunities for improvement and develop change plans for senior management., • Provide reporting at all levels, including Board Level (reporting to the Director of Trading and Operations)., • Share insights on Asset Owner/EPC/BESS trends to inform the commercial team’s future contract negotiations. Preferred skills and experience: • 5+ years of proven experience in project or programme management., • Demonstrable experience of GB market registration — metering, BSC and Elexon processes, BM Unit registration, and pre-qualification for NESO ancillary services., • Background with construction contracts (familiarity with JCT, NEC, or FIDIC standard forms is advantageous)., • The authority and confidence to chair meetings with clients, contractors, network operators and industry bodies, take control of a plan and direct it back to Habitat's requirements., • Ability to articulate complex technical concepts—such as EPC schedules, Elexon metering, connection agreements, and Grid Code compliance—clearly and accessibly across diverse audiences., • Proactive risk management and structured planning, with a strong history of identifying delivery bottlenecks early and escalating them appropriately., • A genuine self-starter. This role runs its own portfolio with minimal supervision. ‘Nice to have’ skills and experience: • Project or Programme management of at least two GB grid-connected generation or storage assets taken from contract execution through to energisation and commercial operation., • Experience with transmission-connected assets and NESO Bilateral Connection or Construction Agreements., • Working knowledge of Capacity Market obligations and the EMR delivery framework., • Exposure to SCADA or EMS deployment on generation assets, and to the protocols above., • Familiarity with optimisation, tolling or route to market agreements from either side of the table., • Formal project management qualification (APM, PRINCE2, PMP). Ultimately we are looking for someone who is a great fit for our company so we encourage you to apply even if you may not meet every requirement in this posting. We value diversity and our environment is supportive, challenging and focused on the consistent delivery of high quality, meaningful work. In return, we’ll give you a competitive salary, flexible working arrangements and a lot of personal development opportunities. We operate a hybrid working model with at least 1 - 2 days in our offices in Oxford. #J-18808-Ljbffr

Gaithersburg, MD, Radnor, PA, Oxford, UK Clinical Development The Executive Director, Early-Stage Clinical Development, Autoimmune will drive assigned autoimmune programs from pre-clinical stages to proof of concept. They will also contribute to the development of infrastructure within Immunocore’s Clinical Sciences department by leading designated projects and workstreams. As the assets develop into the clinic, the incumbent will build a small team. The successful candidate will spearhead Clinical Development strategic planning and be responsible for the design and medical oversight of assigned clinical studies. This includes protocol development, medical monitoring, medical data review, results interpretation, reporting, and regulatory submissions. Additionally, they will lead innovation in trial design, including the development of biomarker strategies. The incumbent is expected to think strategically at both the program and enterprise levels, with the ability to analyze data, troubleshoot programs, and develop risk mitigation plans As a key in-house autoimmune disease expert for R&D, this role requires strong strategic leadership, advisory skills, and close collaboration with cross-functional teams whilst providing oversight, guidance, and mentorship to junior physicians working in early-stage clinical trials. The Executive Director will interact with all levels of management, peers, and leaders from academic centers involved in key collaborations, as well as external stakeholders in the medical and scientific community and global regulatory authorities. The incumbent will work with outstanding people who together pioneer the research, development and commercialization of bi-specific immune modulating therapies. • Apply deep knowledge of the treatment landscape and emerging areas to shape future clinical development strategies and plans for assigned studies and portfolios. Collaborate closely with Project Leaders, Research, Translational, Regulatory, Clinical Operations, Biostatistics, and Clinical Pharmacology colleagues., • Use extensive drug development expertise to design comprehensive clinical development plans, including key decision points, timely readouts, and risk mitigation for both near and long-term goals. Hold clinical matrix team members accountable for achieving clinical objectives., • As the Clinical Development Program Leader, provide strategic clinical leadership to development teams. Generate integrated product development plans that incorporate scientific rationale, regulatory input, competitive landscape, project and portfolio strategy, and advice from patient advocacy groups., • Coordinate and achieve highly complex program objectives through applying advanced expertise, proactively anticipating issues, and developing mitigating solutions. Understand the impact these objectives have to broader corporate strategy., • Design high-quality and innovative clinical trial protocols (including supporting documents such as Investigator’s Brochure and informed consent) for lead autoimmune programs aligned with the Clinical Development Plan and overall product strategy., • Establish and maintain strong relationships with key opinion leaders and partners to facilitate ongoing clinical development, external collaborations and gather insights into Immunocore programs., • Oversee medical aspects of clinical studies, including implementation, medical/safety monitoring, medical data review, results interpretation, and reporting for assigned studies., • Build and manage relationships with relevant CROs, facilitate a thorough understanding of clinical studies, assist in patient recruitment, and ensure trials are executed on time and within budget., • Partner with Regulatory Affairs to lead regulatory strategy, prepare and review regulatory submissions, respond to IRB/EC questions, and participate in global health agency meetings., • Lead the development of publication plans, present clinical data at key meetings, and publish in high-impact journals., • Mentor and develop team members (e.g., Clinical Study Lead) through training, people management, and leadership development. The ideal candidate is an MD or MD/PhD scientist with a clinical perspective, a track record of exceptional achievements in autoimmune therapy development and expertise in multiple disease areas including dermatology and/or type 1 diabetes. They have: • Thorough understanding of the early drug development process including experience contributing to key clinical documents (e.g., protocols, ICF, IB, DSUR, CRF), reviewing and interpreting clinical data., • A strategic and critical mindset with strong problem-solving and analytical skills, as well as a proven ability in designing innovative clinical trials that have supported successful regulatory filings., • Expertise in presenting key headline data with professional authority, anticipating and addressing questions/concerns from senior leadership in a governance setting., • Established links with the medical community globally and locally, with proven ability to develop close working relationships with opinion leaders., • Working knowledge of GCP, ICH, GDP and relevant CFRs is required; familiarity with MHRA, EMA, and CHMP regulations and guidelines and other international regulatory requirements is a plus., • Solid working knowledge of Microsoft applications such as Excel, Access, Word, and Outlook., • Demonstrated ability to build mutually respectful relationships with colleagues, troubleshoot challenges and provide direction, guidance, and support to the team to achieve near-term goals., • Proven team leadership experience, and a view on talent within the industry; ideally having appointed scientists and domain experts into their team., • Ability to facilitate discussions and collaboration among groups with diverse technical expertise, gain alignment and progress decisions on moderate to high complexity issues., • Capable of providing clear direction and holding teams accountable to deliver timely execution of objectives. Motivate and energize cross functional team members to achieve aggressive goals., • Strong oral and written communication skills, professional presence, and demonstrated ability to engage effectively with stakeholders at all levels including senior leaders., • Foundational people management skills with the ability to oversee and manage the activities of junior physicians and clinical scientists, mentor colleagues, and bring the Immunocore vision and strategy to life for others at all levels., • The ideal candidate is an MD or MD/PhD, ideally with relevant training in treating immune mediated diseases., • 5-8 years of relevant experience in clinical drug development OR 2-5 years of relevant clinical development experience with 5-10 years in clinical practice in a related field., • At least two years of experience as a medical monitor in a biopharmaceutical company, and/or CRO., • Strong understanding of pharmacokinetics, biomarkers, statistical principles, and regulatory requirements and demonstrated experience integrating these disciplines in the context of drug development., • A broad understanding of autoimmune disease area; experience in dermatology and / or type 1 diabetes is highly desirable. Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law. #J-18808-Ljbffr

Joining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients. At Harwell, you will play a critical role in advancing Moderna’s clinical development programs by leading the development, qualification, validation, and execution of complex cell-based immunoassays that generate high-quality data to support clinical trials across multiple therapeutic areas. Working at the intersection of immunology, assay science, and clinical development, you will serve as a scientific point of contact within the Immuno-assays group, driving assay excellence while collaborating across multidisciplinary teams and external partners. This is an opportunity to apply deep technical expertise while helping shape innovative approaches, technologies, and data generation strategies that support Moderna’s growing pipeline and future platform capabilities, including increasing exposure to advanced digital and AI-enabled scientific workflows. Serve as a scientific point of contact for cell-based immunoassay development activities supporting clinical programs across multiple therapeutic areas. Be responsible for the quality and integrity of assigned projects supporting Moderna clinical trials. Design, develop, optimize, and execute cell-based immunoassays to support clinical development objectives. Lead assay qualification and validation activities to ensure assays meet scientific, regulatory, and operational requirements. Perform clinical sample testing and analysis, generating robust, reproducible, and high-quality datasets. Conduct testing and data analysis in compliance with applicable GCP and GLP requirements. Deliver high-quality data within established timelines and in alignment with current industry expectations and standards. Perform data acquisition and analysis on clinical specimens and communicate findings effectively to stakeholders. Author technical reports, validation reports, study documentation, and supporting scientific materials. Identify, investigate, and resolve quality-related issues, escalating concerns to management when appropriate. Serve as a Subject Matter Expert (SME) on multifunctional project teams as needed. Represent the Immunoassay Team at project meetings, presenting assay results, data interpretation, development progress, timelines, and recommendations. Collaborate with internal colleagues and external partners to evaluate emerging technologies, novel methodologies, and innovative solutions that address complex scientific challenges. Maintain broad knowledge of industry best practices in cell culture, immunoassay development, assay validation, and clinical sample analysis. Stay informed on new technologies, platforms, critical reagents, and scientific advancements relevant to immunoassay development and execution. Support continuous improvement initiatives that enhance assay performance, laboratory efficiency, data quality, and scientific rigor. Coach and train junior laboratory staff on assay execution, technical procedures, best practices, and compliance requirements. Provide constructive input regarding the strengths, development opportunities, and performance of assigned junior associates. Contribute to periodic performance review discussions for junior team members. Foster a collaborative and inclusive laboratory environment that supports knowledge sharing and scientific excellence. Ensure ongoing compliance with safety, quality, regulatory, and laboratory guidelines at all times. Maintain accurate and up-to-date training records and documentation. Support operational needs that may occasionally require overtime work or weekend coverage. Travel as required to attend training programs, technical conferences, scientific meetings, and industry exhibitions. Report directly to the Associate Director, Immuno-assay UK. We obsess over learning. We don’t have to be the smartest, we have to learn the fastest. We behave like owners. The solutions we’re building go beyond any job description. Ph.D. > 2 yrs or BSC/MSc with >6 years’ experience in immunology, or related field conducting assay validation in clinical Immunology under GLP/GCLP environment. A background in infectious diseases, virology, bacteriology or oncology and experience with handling laboratory pathogens as containment level 3 is an advantage. Experience and deep understanding of cell culture and cell-based assays, particularly viral neutralization assays or bacteriology assays. Strong level of understanding and expertise in design and executing efficacy testing in the context of clinical trial The ability to work in a cross-functional work environment is critical; strong leadership skills and independence skills are expected. Excellent written, presentation and interpersonal communication skills; ability to influence and collaborate in a team environment and with external stakeholders. Candidate will be curious in exploring new technology, bold in proposing creative experimental designs and ideas. Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes Possess strong computational skills, preferably experienced with Word, Excel, Power Point, GraphPad Prism Knowledge of system software for data analysis and statistical analysis. Experience of working in a regulated environment with GLP, GCP, ISO standards is required. As we build our company, we have always believed that an in-person culture is critical to our success. This role is 100% onsite, reflecting the importance of being physically present to support the work, collaborate closely with colleagues, and contribute to our site-based operations. Working onsite enables real-time collaboration, strong team connections, direct mentorship, and the hands‑on partnership needed to deliver our mission. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke-free, alcohol-free, and drug-free work environment. At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well‑being resources are designed to support you—at work, at home, and everywhere in between. • Competitive healthcare, plus voluntary benefit programs to support your unique needs, • A holistic approach to well‑being with access to fitness, mindfulness, and mental health support, • Family building benefits, including fertility, adoption, and surrogacy support, • Generous paid time off, including vacation, bank holidays, volunteer days, sabbatical, global recharge days, and a discretionary year‑end shutdown, • Savingsandinvestments to help you plan for the future, • Location‑specific perks and extras The benefits offered may vary depending on the nature of your employment with Moderna and the country where you work. Since our founding in 2010, we have aspired to build the leading mRNA technology platform, theinfrastructure to reimagine how medicines are created and delivered, and a world‑class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our peopleare the driving force behind our scientific progress and our culture.Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. Moderna is committed to equal opportunity in employment and non‑discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodation or adjustments to qualified job applicants with disabilities. Any applicant requiring an accommodation or adjustment in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations and Adjustments team at . #J-18808-Ljbffr

Our client is a fast-growing niche e-commerce fashion retailer, looking to hire a strategic Operations Director to take ownership of distribution and fulfilment through its next stage of growth. This is a hands‑on leadership role at a pivotal moment. You'll deliver a major warehouse upgrade project, bring in automation, and build a high-performing team, all while raising service levels and keeping costs under control. • Set and deliver the end‑to‑end operations strategy, • Lead the warehouse relocation and automation programme from plan to go‑live, • Own the fulfilment centre P&L and the KPIs that drive it, • Build, coach and develop a strong operations team, • Get more from carrier partnerships and take cost out of the supply chain, • A track record leading operations in a high‑growth B2C or e‑commerce business, • Deep expertise in pick-pack-ship fulfilment and logistics, • Strong commercial acumen and a tech‑first approach to problems, • Hands‑on experience of warehouse moves and automation projects, • A drive for operational excellence and a genuine focus on the customer All applicants must have an unrestricted right to work in the UK as our client will not support visa sponsorship for this role. #J-18808-Ljbffr

The New Foscote Hospital, part of the Akessa Health Care Group, is looking for an experienced dynamic and organised ODP or scrub nurse, to join our team. This role is due to a long standing colleagues planned retirement after decades of service at this hospital. This is an exciting time to join a hugely reputable organisation and provide the highest standards of care, with significant investment having been made into the hospital with laminar flow operating rooms. In considering this role please note that: • This appointment is for an energetic and ambitious individual, • Our colleagues lead by example, • Akessa Health Care does not support hybrid working, • Akessa Health Care is expanding and there are ample opportunities for personal and career development in this role., • To assist the Theatre Manager and Deputy Theatre Manager in the delivery, standards and management of patient care within the theatre., • Provide skilled assistance to the surgeons, • Work as part of a multi-disciplinary team, providing high quality pre and post-operative patient-centred care and customer service., • Provide guidance, support and clinical scrub expertise and leadership to the Theatre team, whilst working closely with the senior team to ensure effective use of Theatre resources., • Demonstrate clinical expertise in specialist area and act as a resource to proactively enhance the service to our clients., • Ensure that the theatre is prepared for use on a daily basis in line with quality standards., • Comply with internal procedures to ensure equipment is maintained/serviced in line with manufacturers instructions, reporting any defects and notifying the Theatre Manager and Deputy Theatre Manager., • Ensure that all required documentation (legal, quality or other) is accurately maintained., • In accordance with policies and procedures, ensure that medicines administration and management is carried out appropriately., • Coordinate and maintain adequate stock levels of drugs, stores and implants liaising with the Theatre Manager and / Procurement., • Maintain effective communication across the Hospital, including with patients, team members and Consultants. Akessa Healthcare Group owns and operates several boutique independent hospitals including The New Foscote Hospital, Royal Buckinghamshire Hospital and 107 Harley Street. The New Foscote Hospital has been successfully established in Banbury for over 40 years and has provided services and treatments to thousands of people from across the region. We have over 75 consultants, all of whom are leaders in their specialist fields and choose to hold their private practice here, working alongside our friendly, highly qualified and experienced nursing staff and support teams. The Royal Buckinghamshire Hospital was established in Aylesbury in 1832 and has provided services and treatments to thousands of people from across the region. The ownership of the hospital was transferred to our new management team in January 2023. By joining our existing portfolio, the hospital is now run professionally and provides clinical care to private, insured and NHS patients, with a strong ethos on caring for our staff. Since 2023 the hospital has undergone a multimillion pound refurbishment project. 107 Harley Street, is an outpatient, diagnostic and day-case facility. The Group has had a presence in the Harley Street area since 2010. The treatments offered at this facility includes oral and maxillofacial surgery, dermatology, orthodontics and specialist dentistry, plastic and cosmetic surgery, general surgery and rheumatology. The clinical outcomes of the hospital group are of the highest standards and the latest CQC report rated our hospital standards as good across all parameters. Our organisation has strong IT, operational, clinical governance and accountancy support. All colleagues are encouraged to feel empowered and to have an active voice on the management of their services. Akessa Healthcare is managed and run by clinicians. All colleagues are encouraged to feel empowered and to have an active voice on the management of their services. Our organisation has a strong IT, operational, clinical governance and accountancy support. The team at this hospital group takes great pride in what we do. The clinical outcomes at The New Foscote Hospital are amongst the best in the world. The hospital was rated amongst the top 10 hospitals in UK, both private and NHS, for its patients experiences. • Registered with the NMC or HCPC essential., • Strong clinical background as a Senior Scrub Practitioner in all types of surgery including orthopaedics., • Surgical First Assistant trained/qualified desirable, • Ability to demonstrate high standards of verbal and written communication., • Strong time management and organisational skills., • Ability to work flexibly, take accountability and respond to urgent matters in a calm, well-measured and informed manner., • Ability to present information accurately, clearly and concisely. Full-time, Permanent Depending on experience (Agenda for Change Band 7) • Company events, • Company pension, • Cycle to work scheme, • Discounted or free food, • Employee discount, • Free flu jabs, • Health & wellbeing programme, • Private medical insurance, • Referral programme, • Store discount NMC or HCPC Registration (required) United Kingdom (preferred) In person 10 November 2026 Kaveh Shakib, Medical Director, #J-18808-Ljbffr

The Executive Director, Drug Metabolism & Pharmacokinetics, will lead the DMPK team at our Oxford site and will be part of the Global DMPK and Oxford Site leadership teams. The responsibilities of the role include developing and executing the strategy and operations of the Oxford DMPK team, as well as the scientific and managerial coordination of its groups and employees. This role will optimise interdisciplinary activities within DMPK and integrate activities with those of the other sites and departments, and thus, play a major role in shaping the direction of the overall Vertex portfolio. Using deep scientific expertise and strong leadership skills, this role will provide strategic and scientific direction to help advance the discovery and development of transformational therapies for serious unmet medical needs at Vertex. • Develop a strategy and vision for the Oxford DMPK team that is aligned with the Global DMPK and Vertex R&D vision/mission, • Develop and execute DMPK scientific strategies to address ADME challenges in discovery and development programs, • Build and maintain strong collaborative partnerships with Medicinal Chemistry, Biology, Preclinical Safety, Clinical Pharmacology, CMC and other R&D disciplines to advance Vertex programs through discovery and development., • Represent DMPK function on drug discovery and development teams, at the Oxford site and with Vertex governance bodies, • Implement innovative technologies and approaches to enhance scientific impact and/or efficiencies., • Provides scientific and managerial leadership to their team in prioritising and executing on key deliverables and project needs, • Ensure completion of necessary DMPK regulatory documentation and reports to support drug development, including Investigator Brochures, INDs (or equivalent), and marketing applications., • Hire, develop, manage and retain key talent to maintain a high-performing team., • Develop internal and external sourcing strategies and liaise across sites to best meet project needs. Contribute to developing Global DMPK resource allocation, staffing needs, expenses, and capital budgeting, as well as implementation plans., • Participate in the review of business development opportunities, • Strong management and leadership skills, with emphasis on developing and mentoring junior scientists to create a high-performing team, • Successful track record and experience in a DMPK lead role on multiple R&D teams across more than one therapeutic area. Extensive experience working with small molecules is a must. Additional expertise and familiarity with one or more other modalities (e.g., protein, antibody and nucleic acid therapeutics, cell and gene therapies) is desired., • Deep scientific and strategic expertise in various components of DMPK science such as in vitro and in vivo ADME assays, mass spectrometry and bioanalysis, pharmacokinetic data analysis, biotransformation/disposition pathways, drug interaction risk assessment and human dose and drug interaction predictions. Additional skills in areas such as transporter science, enzymology and PK/PD and PBPK modelling will be a plus., • Ability to critically evaluate and implement new science and technology as it relates to the discovery and development of new medicines, • Excellent verbal, written and interpersonal communication skills, and ability to develop and grow strong cross-site/function collaborations, • Proven experience in a similar role is required after a PhD or the equivalent combination of education and experience. At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. On-Site Designated In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com #J-18808-Ljbffr

Aioi R&D Lab – Oxford is an AI R&D company based in Oxford, on a mission to harness AI to understand, predict, and manage risk, helping build a safer, more resilient society. We sit at the intersection of academia and industry, working with Oxford's professors, researchers, and graduates alongside commercial spinouts and partner companies, to turn frontier research into AI that actually ships rather than just gets published. Our work spans applied AI for insurance and adjacent industries, including supply chains, nature, autonomous driving, and the emerging challenges nobody's solved yet, alongside deep research of our own into agentic AI, privacy-preserving technologies, trustworthy AI, complex systems modelling, and quantum computing. We build AI products and solutions for insurers, businesses, and public-sector organisations worldwide, and run innovative research projects that push these technologies further, helping people make better decisions in an uncertain world. You’ll support the successful delivery of the CODAS R&D Programme: a large-scale, multi-partner, international AI research programme funded by the Japanese government and delivered in collaboration with leading research, technology and industry partners. The role combines project management, programme controls, financial reporting and operational engagement responsibilities. Working closely with the Programme Director, Finance teams, Track Leads and programme partners, the role will coordinate the preparation, validation and delivery of programme financial and operational reporting, ensuring information provided to Japanese stakeholders is accurate, timely and aligned with programme governance, contractual obligations and funding requirements. Leveraging Japanese language skills and an understanding of Japanese business practices, the role will act as a key liaison between UK and Japanese programme teams, facilitating effective communication, financial transparency and operational collaboration while supporting the day-to-day delivery of programme activities and programme milestones. The purpose of the role is to ensure: • Programme financial information, expense reporting and supporting evidence are accurately coordinated, validated and prepared to support reporting to Japanese programme partners and funding bodies., • Financial and operational reporting is delivered in a timely manner, supporting effective programme governance, funding compliance and informed decision-making by the Programme Director., • Strong working relationships are maintained between UK and Japanese stakeholders, enabling effective communication, collaboration and programme delivery., • Programme governance, documentation and reporting activities are effectively coordinated in support of contractual, regulatory and funding obligations., • Coordinate the preparation and submission of programme financial and expense reports to CODAS, NEDO and Japanese programme stakeholders, ensuring expenditure is accurately recorded, appropriately evidenced and reported within required timescales, while supporting the Programme Director in fulfilling programme reporting obligations., • Validate that financial records and supporting documentation are complete, accurate and compliant with programme funding requirements, including quotations, purchase approvals, invoices, proof of payment, timesheets, labour records and other required evidence., • Work closely with Finance teams, Track Leads and programme contributors to resolve discrepancies, obtain missing documentation and improve the quality and accuracy of reporting prior to submission., • Maintain accurate financial reporting trackers, expenditure records and budget monitoring information, ensuring programme spend is effectively tracked against approved budgets and that records remain current, traceable and audit-ready., • Support financial forecasting, expenditure monitoring, audits, funding inspections and information requests by maintaining organised financial records and ensuring supporting evidence can be readily accessed and validated., • Act as the primary operational liaison for programme financial reporting with Japanese stakeholders, using Japanese language skills and an understanding of Japanese business practices and reporting expectations to support effective communication and collaboration., • Demonstrable experience in programme financial reporting, budget monitoring and financial administration, supported by a relevant financial qualification (e.g. CIMA)., • Advanced Excel skills, including Pivot tables, LOOKUP, complex formulas and financial reconciliations, with the ability to build audit ready reporting and maintain high levels of data integrity., • Experience coordinating financial reporting, programme controls or reporting activities within complex projects or programmes., • Experience managing expense reporting, financial records and supporting documentation., • Strong attention to detail, with the ability to validate financial information and audit evidence., • Experience working with Finance teams to prepare management information and programme reports., • Fluent in Japanese and English, with strong written and verbal communication skills., • Strong Excel skills, including Pivot Tables and VLOOKUPs, with experience managing large volumes of data., • Proven ability to work effectively in a fast-paced, deadline-driven environment and manage multiple priorities. We're all about helping you grow, with plenty of support to develop in your current role whilst also creating opportunities to explore new ones and advance your career. We realise that we need to be a good fit for you above all else– so here’s what you can enjoy about AND‑E: • Recognised as the Best Large Insurance Employer: We are proud to have been named the Best Large Insurance Employer for 2023 at the prestigious British Insurance Awards., • Unmatched Work-Life Balance., • Competitive Salaries and Benefits Package: We offer competitive salaries that recognise your skills and expertise. We champion choice, flexibility, and balance in both work and home life. Our commitment to diversity, equity, and inclusion ensures everyone feels valued and supported— including embracing neurodiversity and providing the tools needed to thrive. We like to think our benefits package is one of the best, focusing on colleagues’ health, wealth, and lifestyle. We offer: • Up to 28 Days annual leave with the option to buy/sell up to 5 days holiday*, • Healix Private Medical Insurance Options*, • 3 x Annual Salary Life Assurance*, • A range of health, wellbeing, and financial support benefits, including money back on health expenses, Employee Assistance Programme, Flu Jab voucher, Virtual GP service, and driving lessons* for you and your family., • Additional perks such as a pension advisory service, family-friendly policies, season ticket loan, cycle scheme, and financial flexibility through Wagestream*., • Subject to company performance and completion of probation Aioi Nissay Dowa Europe is committed to promoting equal opportunities in employment. Employees and job applicants will receive equal treatment regardless of age, disability, gender reassignment, marital or civil partner status, pregnancy or maternity, race, colour, nationality, ethnic or national origin, religion or belief, sex or sexual orientation (Protected Characteristics) At AND‑E, equal opportunity is more than a policy—it’s a promise. We welcome applications from all individuals regardless of age, disability, gender identity, marital status, pregnancy, race, religion, sexual orientation, or any other protected characteristic. Reasonable adjustments: If you require any adjustments to support you during our recruitment process, please let us know. We’re committed to making the process accessible and are happy to help #J-18808-Ljbffr

Finance Manager (Financial Modelling and Business Support) for a leading residential developer in the South East. Potensis is pleased to partner with a trusted developer and is recruiting a Finance Manager who will be a key member of the Finance team and help the business achieve its long-term growth plans. Salary information: Potensis provided pay range; actual pay will be based on your skills and experience – talk with your recruiter to learn more. • Preparing month end balance sheet reconciliations and management accounts, monthly journals and account analysis., • Assist in the preparation of the monthly forecasts., • Work as the secondary divisional contact, covering for the Finance Director as required., • Ensure that all cash flow forecasts are as accurate as possible., • Implement and oversee regional financial policies aligned with Group standards to ensure robust governance., • Provide financial insight at local Board and Valuation Review meetings to support strategic decision-making., • Identify and deliver opportunities to streamline financial processes and enhance system efficiency., • Manage the interim and year end process with external auditors through to sign off for the division and prepare divisional reporting returns., • Experience of working within a similar role would be preferred., • Experience of working with accountancy software., • CIMA, ACCA or ACA qualified., • Advanced Microsoft Excel, Financial modelling and proficient IT skills (Word, Outlook)., • Excellent administration and organisation skills., • Strong analytical, numerical, problem-solving abilities., • Excellent written and verbal communication skills. This is an excellent opportunity with a leading residential developer who can offer an excellent all-round package and realistic opportunities for future progression. For further information, please apply today. • Seniority level, • Mid-Senior level, • Employment type, • Full-time, • Job function, • Project Management, • Industries, • Accounting, Financial Services, and Real Estate #J-18808-Ljbffr

At Sir Robert McAlpine, we are proud to be building Britain's future heritage. We have an exciting opportunity for a Digital Construction Manager to join our team on a major project in Oxford, delivering state-of-the-art laboratories and research facilities. Our Team improves predictability and construction project performance with smart, digital tools and services which enable faster project delivery with greater quality, consistency and efficiency. As a team we value creativity, innovation, digital leadership & collaborative relationships. In the 158 years since our foundation, Sir Robert McAlpine has worked on some of the country's most iconic buildings and projects. Our success through the decades has been down to our people - we're a family-owned business with a culture that brings out the best in individuals and teams. Right now, we're excited about continuing our legacy. This is where to achieve more from your career, by proudly building Britain's future heritage with us. The Main responsibilities of the Digital Construction Manager will be: • To cover multiple Digital/BIM/Information Management tasks for the lifecycle of a construction project on site, including work winning, design phase, pre-construction phase, construction phase, handover and soft landings, • Work closely with the wider project team, client team and trade sub-contractors. Having regular contact with the Principal Digital Construction Manager and Director for Digital Construction, • Lead and facilitate the integration of Digital Construction implementation, driving the SRM digital construction strategy and business culture in a manner which upholds the Visions and Values of the Company, • Line managing, coaching and mentoring Digital construction staff and supporting personnel development., • Relevant BIM Qualifications/Courses, • 3 years minimum experience implementing BIM within the construction industry, • Working knowledge of Revit, Navisworks, Solibri, Viewpoint 4 Projects and COBie, • Knowledge of industry standards ISO19650, • Excellent communicator and ability to manage challenging scenarios, • Desirable skills in data analytics and reporting, • A natural affinity for being ambitious, dynamic and a strong team player We're ready to invest in you and your future, and offer wide-ranging, performance-related progression opportunities. Our competitive rewards packages feature flexible benefits to fit your lifestyle and priorities. We'd love you to join us in proudly building Britain's future heritage. Sir Robert McAlpine is focused on being a truly inclusive employer, even if you don't meet every single requirement, we'd still love to hear from you. Especially if you're part of a group that is under-represented in Construction. Our goal is for Sir Robert McAlpine to proportionally represent the diversity of the working population in society. As a family-run business with strong family values, our aim is to ensure that Sir Robert McAlpine is a supportive, empowering and inclusive environment for every member of our team. #J-18808-Ljbffr

Our client is an established, award-winning architectural practice with a strong reputation across Healthcare, Education, Defence, Heritage and Commercial architecture. Following the successful acquisition of several major projects and frameworks, they are looking to strengthen their established team with an experienced architectural leader who can play a key role in the continued growth and development of the practice. With a significant pipeline of secured work, including major Healthcare and Commercial frameworks, this is an exciting opportunity for an ambitious Associate or Director to progress towards equity partnership within a well-established practice. The successful individual will have the opportunity to take on a strategic position, combining project leadership with business development, client relationship management and the development of new opportunities. The role will involve overseeing a varied portfolio of projects, from Healthcare and Education schemes through to Defence, Commercial refurbishments, new-builds and listed or heritage buildings. Project values typically range from £1m-£2m, with larger schemes extending up to £10m. You will take a leading role in the delivery of projects, maintaining strong relationships with clients, consultants and contractors while providing strategic direction and technical oversight to project teams. All projects are Partner-led, with the successful individual taking responsibility for multiple schemes and providing senior-level input on project delivery, coordination, technical matters and problem solving. The role will combine hands-on project leadership with the wider responsibilities of running and growing an architectural practice. You will oversee project teams, provide technical guidance and support the development of Architects and Architectural Assistants, while maintaining responsibility for project performance, client relationships and the successful delivery of schemes. Alongside project delivery, you will be instrumental in developing existing client relationships, identifying new business opportunities and strengthening the practice's position across its key sectors. The practice places particular importance on experience with Higher-Risk Buildings (HRBs) and Building Regulations Principal Designer (BRPD) responsibilities. Experience in these areas would be highly advantageous, particularly for candidates with a background in Healthcare, Commercial or Education projects. The position would suit an established Associate Architect or Director looking to take the next step in their career, or an experienced Architect with a strong track record of leadership, commercial awareness and business development. There is a genuine opportunity to progress towards equity partnership within a few years, depending on the individual's experience, contribution and ambitions. • Salary of £65,000-£70,000, dependent on experience., • Hybrid working - typically 3 days in the office / 2 days remote, • 24 days annual leave plus bank holidays, • Pension scheme, • Private healthcare., • Professional memberships paid for., • Cycle to work and other employee benefits., • Regular networking and industry events., • Office trips and team activities., • Opportunity to lead and influence a growing portfolio of high-quality architectural projects., • Genuine opportunity to progress towards equity partnership within a few years., • Equity ownership and profit share upon appointment as an equity Partner., • Company-funded car upon appointment as an equity Partner. The opportunity to influence business development, client relationships and the future direction of an established, award-winning practice. • Qualified Architect with substantial post-Part 3 experience and a strong track record of architectural project delivery., • Proven experience operating at Associate, Director or equivalent senior leadership level, or demonstrable readiness to step into an Associate position with a clear pathway towards partnership., • Strong experience leading projects from concept through to completion, with excellent technical and design capability., • Proven ability to manage client relationships, lead project teams and oversee multiple projects simultaneously., • Experience providing senior technical oversight, coordinating project teams and supporting the development of less experienced Architects and Architectural Assistants., • Demonstrable business development experience, including identifying opportunities, developing client relationships and contributing to the successful acquisition of new work., • Experience working within frameworks and managing relationships with key clients would be highly advantageous., • Strong commercial awareness, with the ability to contribute to financial performance, resource planning and the wider strategic direction of the practice., • Experience working on Higher-Risk Buildings (HRBs), with a strong understanding of the associated technical, regulatory and compliance requirements., • Experience undertaking Building Regulations Principal Designer (BRPD) responsibilities, or a strong understanding of the relevant legislation and requirements., • Good knowledge in either Revit or AutoCAD., • Strong communication, negotiation and leadership skills, with the ability to represent the practice confidently at client meetings and industry events., • A proactive, entrepreneurial approach, with the ambition to help drive the continued growth and success of the business. If you're an experienced architectural leader looking for a role that combines project delivery, strategic influence and business development, this is an excellent opportunity to join an established Oxford practice with a strong pipeline of secured work and a genuine pathway towards equity partnership. #J-18808-Ljbffr

Replimune’s mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care because patient’s lives depend on it. At Replimune, we live by our values: United: We Collaborate for a Common Goal. Audacious: We Are Bold. Dedicated: We Give Our Full Commitment. Candid: We Are Honest With Each Other. People are at the center of everything we do, and when it comes to our employees, we make it personal. With a deep sense of purpose, a strong and evolving culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to impact on the lives of patients, caregivers and themselves. Join us, as we reshape the future. The Associate Director - Process Development is responsible for managing the Process Development team at Replimune’s Milton Park facility. The Process Development team at the Milton Park facility collaborates with their PD colleagues in the US to characterize and improve process steps within the cGMP production processes by executing robust bench scale process experiments. The Process Development team at Milton Park is also responsible for the generation of materials to support other departments/studies (assay controls, assay buffers, preclinical / tox material, etc.). The Associate Director will ensure that all work is planned, performed, and reported in an efficient and compliant manner. This position is based in our Milton Park location and typically has a 5-day on-site expectation. • Leading the Process Development group at Replimune’s Milton Park facility, UK., • Ensuring lab work is executed as per experimental design instructions (SOP, protocol, batch record, etc.) in a safe and efficient manner., • Production of suitable material for QC / AD assay controls, preclinical and toxicology studies, etc., • Author / reviewer of reports, protocols, SOPs, batch records, etc., • Drive continuous improvement in our cGMP process steps through application of experimental findings., • Supervises timely creation, completion and archiving records, protocols and technical reports to document the development, characterization and technology transfer pf production processes., • Ensure effective, high-quality, timely and appropriate documentation in laboratory notebooks., • Milton Park PD representative for cross-functional site leadership / administrative meetings., • Practices and promotes safe work habits and adheres to safety procedures and guidelines, • PD representative for audits of Milton Park facility., • Provide regular updates of Milton Park PD group activities to senior management., • Keeps up to date with current technologies and trends in biologics processing, • Some travel may be required, both in country and international., • Bachelor’s degree in applicable field with advanced degree preferred., • A minimum of 10 years’ experience (BS) or 6 to 8 years (MS/PhD) in biologics process development or manufacturing, • Thorough understanding of current regulatory requirements and practical experience in support of cGMP operations, • Proven leadership in managing and motivating team members to achieve goals, • Ability to interface effectively with management and other groups or project teams, • Excellent verbal and written communication skills Replimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of a novel portfolio of oncolytic immunotherapies. Replimune’s proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit www.replimune.com. We are an Equal Opportunity Employer. #J-18808-Ljbffr

Prolific is not just another player in the AI space – we are building the biggest pool of quality human data in the world. Over 35,000 AI developers, researchers, and organizations use Prolific to gather data from paid study participants with a wide variety of experiences, knowledge, and skills. We're looking for Operations and PMO leaders with hands‑on experience in operations, project governance, portfolio management, and operational planning to join our Expert Network as subject matter experts. If you have the necessary experience, we'll send you a quick 10- to 15-minute test to assess your skills and suitability for our research tasks. If successful, you'll be invited to join Prolific as a participant, where you'll get paid to share your expertise with researchers and organisations who need real‑world planning and operations insight. Researchers looking for your skills tend to pay up to $200 per hour. You must be prepared to complete paid tasks that require one hour of uninterrupted work, though many are shorter. • Professional Experience: Director‑level or above experience in an Operations or PMO function across sectors such as Manufacturing, Healthcare, Retail, Technology, Professional Services, Financial Services, Utilities, or Government., • Domain Knowledge: deep background in one or more areas such as project governance, resource planning, portfolio management, capacity planning, or operational strategy., • Planning Tool Experience: current or recent hands‑on use of a planning or PPM platform such as Microsoft Project, Planview, Smartsheet, Jira, or ServiceNow., • Analytical Thinking: the ability to draw on complex planning workflows and portfolio experience to answer research questions and provide clear, nuanced expert insight., • Communication: exceptional written communication skills and a high level of attention to detail when responding to questions on project governance, operational planning, or portfolio management topics., • A PayPal account to receive payment from our clients, • Answering Research Questions: share your expert perspective on topics such as project prioritisation, resource allocation, portfolio governance, and operational planning processes., • Scenario Review: apply your real‑world experience to assess and respond to planning and PMO scenarios, such as programme governance cycles, capacity reviews, milestone escalations, and budget forecasting workflows., • Surveys & Interviews: participate in structured surveys or interviews where your domain expertise informs research into planning practices and PMO operations., • Product & Process Feedback: provide informed feedback on tools, workflows, and processes related to planning and portfolio management platforms in operations and PMO contexts., • Framework Input: contribute subject matter expertise to help research teams better understand how Operations and PMO functions use and evaluate planning tools and governance frameworks. Joining our platform as a Prolific participant will give you the chance to influence the AI models of the future using professional legal expertise. Once you pass our assessment, you can join Prolific in just 15 minutes, and start enjoying competitive pay rates, flexible hours, and the ability to work from home. We've built a unique platform that connects researchers and companies with a global pool of participants, enabling the collection of high-quality, ethically sourced human behavioural data and feedback. This data is the cornerstone of developing more accurate, nuanced, and aligned AI systems. We believe that the next leap in AI capabilities won't come solely from scaling existing models, but from integrating diverse human perspectives and behaviours into AI development. By providing this crucial human data infrastructure, Prolific is positioning itself at the forefront of the next wave of AI innovation – one that reflects the breadth and the best of humanity. • Website, • Youtube By submitting your application, you agree that Prolific may collect your personal data for recruiting and global organisation planning. Prolific's Candidate Privacy Notice explains what personal information Prolific may process, where Prolific may process your personal information, its purposes for processing your personal information, and the rights you can exercise over Prolific use of your personal personal information. #J-18808-Ljbffr

Job Summary: Responsible for leading and managing an independent research group within the Generative Biology Institute (“GBI”), delivering a program of bold, ambitious and transformational research which is broadly aligned with GBI’s vision of making biology engineerable and unlocking its potential for good Generative Biology Institute The vision of the GBI is to lay the foundations for engineering biology, and unlock its potential for good. To achieve this, we must overcome two key challenges. First, we need the ability to write in the natural language of biology, enabling the rapid and scalable synthesis of entire genomes with precision. Second, we must understand what to write, determining which DNA sequences will generate biological systems that perform the desired functions. Addressing these challenges will allow us to harness the full power of biology to create transformative solutions across health, agriculture, clean energy and more. Part of the Ellison Institute of Technology, Oxford (“EIT”), GBI is led by founding Director Jason Chin. It will house 30 groups and more than 500 researchers at scale, focused on solving the two critical challenges in making biology engineerable and applying the solutions to addressing the global challenges encapsulated in EIT’s Humane Endeavors. GBI will have sustained and substantial funding to support the unique scale and ambition of its ground-breaking vision for engineering biology. GBI researchers will also be supported by cutting edge facilities including mass spectrometry, flow cytometry, sequencing, automation, scientific computing, bioinformatics, and machine learning. GBI will also have access to substantial compute resources that can be leveraged to further accelerate progress. The environment at GBI will allow researchers to undertake ambitious, long-term, collaborative research, and we will actively support the translation of research to commercial applications, where appropriate. GBI will commence operations in 2025. The team will work from a purpose-made facility in the Oxford Science Park, currently under construction. Once complete, this state-of-the-art facility will include more than 40,000 m² of research laboratory and office space. Ahead of the launch of GBI in Q4 2025, we are now accepting applications for PrincipalInvestigator positions at all levels, including Senior PrincipalInvestigator (equivalent to Tenured Professor) and PrincipalInvestigator (equivalent to a Tenure-Track Professor) as we build a world-class faculty. We expect to make 5 or more appointments before the end of 2026, with further appointments in 2027 and 2028 as we scale. Ellison Institute of Technology, Oxford (“EIT”) EIT’s purpose is to have a global impact by fundamentally reimagining the way science and technology translate into end-to-end solutions and delivering these solutions in programs and platforms that respond to humanity’s most challenging problems. EIT is investing significant resources in a new world-class research and development facility in the Oxford Science Park, including GBI. EIT is committed to cultivating a community where excellence is achieved through collaboration, trust, innovation and tenacity. We foster an environment where everyone’s experience and expertise are valued. We are curious and resilient in our efforts to drive long-term, sustainable innovation to meet humanity’s most enduring challenges. Key Responsibilities: • To set the research direction for your group and ensuring research activity is consistent with that direction and directly relevant to GBI’s vision., • To recruit and manage a group of outstanding researchers, which may include postdocs, doctoral students (in partnership with the University of Oxford, we are establishing a doctoral programme in Generative Biology with up to 20 fully funded doctoral student positions per year), research assistants and other scientists., • To mentor highly promising early career researchers to achieve the group’s goals and progress their aligned career objectives., • To collaborate with other groups within GBI and with colleagues within the broader EIT family to deliver bold, ambitious and transformational research that would not be possible within an individual group., • To help shape the facilities in GBI as part of the scientific strategy for delivering GBI’s vision. Essential Knowledge, Skills and Experience: • A PhD in a relevant scientific discipline, such as synthetic biology, computational biology and AI, microbial, plant and human cell biology, genomics, robotics and automation, and nucleic acids chemistry., • A strong publication record in your field, demonstrating the ability to deliver bold, ambitious and transformational advances., • Track record of building and managing collaborations, both internally and with external academic and/or industry partners, to enhance research capabilities., • Strong communication and leadership skills, with the ability to engage with senior researchers, technical teams, and external stakeholders., • We welcome applications from researchers who have experience running their own group as a Professor, Associate Professor, or Assistant Professor, and from those seeking their first independent position., • We also actively encourage applications from those who have worked in an commercial setting, such as a biotech and companies leveraging AI for research., • Assessment of applicants with respect to knowledge skills and experience criteria will be calibrated for career stage. Our proposition for our PrincipalInvestigators: • Research groups will be supported by substantial core funding, for posts, consumables, and equipment matched to the needs of the project., • Additional posts can be made available to support specific research projects, particularly for ambitious collaborative projects across groups., • Group leaders will have the ability to also supervise graduate students and participate in the doctoral program in generative biology being established through the University of Oxford-EIT alliance., • Access to cutting-edge facilities and infrastructure, initially including mass-spectrometry, flow cytometry, imaging, automation and, sequencing, with intention to expand facilities, in line with GBI’s scientific strategy, as we scale., • Access to significant compute capacity and capability, including in partnership with EIT’s AI team., • Group leaders will be encouraged to publish work from their group., • Opportunity to translate research with commercial application into a separate company in partnership with GBI’s translational team and with financial and operational support from EIT., • Where appropriate, we will support applications for faculty appointments at Oxford University, building on the University of Oxford-EIT Alliance We offer the following benefits: • Globally competitive salary and bonus., • Pension and travel allowance., • Training and development opportunities., • Additional benefits including enhanced holiday pay, life assurance, income protection, private medical insurance, hospital cash plan, therapy services, perk box. Terms of Appointment: • You must be eligible to work in the UK with a willingness to travel as necessary. We are open to sponsoring employment visas for this role; however sponsorship is not available for all visa types or in all circumstances. Eligibility will be assessed on a case-by-case basis., • You must be based in, or within easy commuting distance of, Oxford., • During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of our work. Your application Please submit a CV (no more than 3 pages, including a list of up to ten key publications), and cover letter explaining why you would like to join GBI (no more than 2 pages) Please submit a proposal (no more than 5 pages) of the research that you would like to undertake at GBI covering: • The research questions that you would like answer over a 5-10 year period and how this relates to the vision of GBI., • How this relates to your previous work., • The challenges that you need to overcome and the resources that you would need in order to be successful., • How you would intend to partner with colleagues at GBI and with the broader EIT family. We are interested in all research that is consistent with GBI’s vision. Some relevant areas include: • Molecular and Cellular Design and Evolution., • Enzyme design., • Design of molecular assemblies and machines., • Experimental accelerated evolution., • Robotics, automation and autonomous labs., • Genome mining and informatics-based discovery., • Computational AI sequence to function., • Modelling and building genetic and cellular circuits., • Cellular design., • Expanding chemistry in biology., • Nitrogen fixation., • Carbon fixation., • Programming cellular assemblies and synthetic tissues., • Scalable error free DNA and genome synthesis., • Microbial Genome Synthesis and Design., • Gb-scale Genome Synthesis for plants, human cells and animals., • Combinatorial synthetic genomics., • DNA delivery., • Predictive models of DNA sequence to function, at the scale of genes and genomes., • Human health applications and delivery mechanisms. We will be recruiting PrincipalInvestigators over the next 2–3 years, with applications reviewed every one to six months as part of a rolling selection process. #J-18808-Ljbffr

An independent Oxford construction consultancy is looking to appoint a Senior Quantity Surveyor to join its growing cost management team. The successful Senior Quantity Surveyor will work across a varied portfolio of science, education, commercial and residential projects throughout Oxford and the wider region. The Senior Quantity Surveyor will take ownership of commissions from early feasibility and cost planning through procurement, construction and final account. Working directly with clients, consultants and contractors, the Senior Quantity Surveyor will provide clear commercial advice, manage project costs and help shape procurement strategy. The Senior Quantity Surveyor will also support junior colleagues while building strong relationships with clients across Oxford's property and development market. This position would suit a Senior Quantity Surveyor who wants greater autonomy within a smaller, hands-on consultancy environment, while retaining access to technically interesting and varied projects. • Degree qualified in Quantity Surveying, Commercial Management or a related construction discipline, • Strong UK PQS / construction consultancy experience, • MRICS qualified or actively working towards chartership, • Proven pre- and post-contract cost management experience, • Confident preparing cost plans, tender documentation and procurement advice, • Experience managing valuations, variations and final accounts, • Good knowledge of JCT contracts and UK procurement routes, • Experience across science, education, commercial or residential projects would be advantageous, • Strong client-facing, reporting and communication skills, • Able to manage several commissions with limited supervision, • Comfortable mentoring junior Quantity Surveyors, • Ambitious Senior Quantity Surveyor looking to progress towards Associate level, • £70,000 - £80,000 per annum, • Oxford-based position, • Varied and technically interesting project portfolio, • Direct client and project responsibility, • Strong professional development support, • Opportunity to mentor junior team members, • Clear progression towards Associate level, • Collaborative consultancy environment with greater project autonomy Reference #DM23274 Quantity Surveyor / Project Manager / Project Management / Employers Agent / Surveying / Construction / Building Surveyor / MRICS / MICOB / MAPM / FRICS / Contract Administration / Associate Director / Construction Consultancy #J-18808-Ljbffr

At the Ellison Institute of Technology (EIT), we're on a mission to translate scientific discovery into real world impact. We bring together visionary scientists, technologists, engineers, researchers, educators and innovators to tackle humanity's greatest challenges in four transformative areas: • Health, Medical Science & Generative Biology, • Food Security & Sustainable Agriculture, • Climate Change & Managing CO₂, • Artificial Intelligence & Robotics This is ambitious work - work that demands curiosity, courage, and a relentless drive to make a difference. At EIT, you'll join a community built on excellence, innovation, tenacity, trust, and collaboration, where bold ideas become real-world breakthroughs. Together, we push boundaries, embrace complexity, and create solutions to scale ideas from lab to society. Led by Founding Director Jason Chin, the Generative Biology Institute (GBI) at the Ellison Institute of Technology is tackling the key challenges in making biology engineerable, and thereby releasing the unrivalled power of biology for the benefit of humanity. The vision of GBI is to lay the foundations for engineering biology, and unlock its potential for good. To achieve this, we must overcome two key challenges. First, we need the ability to write in the natural language of biology, enabling the rapid and scalable synthesis of entire genomes with precision. Second, we must understand what to write - determining which DNA sequences will generate biological systems that perform the desired functions. Addressing these challenges will allow us to harness the full power of biology to create transformative solutions across health, agriculture, clean energy and more. The Generative Biology Institute commenced operations in 2025, occupying newly renovated bespoke space in the Oxford Science Park. The team will later move to a purpose-made facility in the Oxford Science Park, currently under construction. Once complete, this state-of-the-art facility will include more than 40,000 m² of research laboratory and office space. It will house over 30 groups and up to 600 employees at scale, focused on solving the two critical challenges in making biology engineerable and applying the solutions to addressing the global challenges encapsulated in EIT's Humane Endeavours. The AI & Robotics team at EIT brings together AI research, robotics and scientific expertise to make biological matter computable and testable, at scale, and by any scientist. We build generative and predictive models of biological molecules and systems, physics grounded simulation and design tools, and autonomous laboratories that generate the data these models learn from and test the designs they propose. You will be joining the project Monera, a joint project across the Generative Biology Institute and the AI & Robotics team building multi-modal generative models of whole organisms, starting with Escherichia coli in order to understand and predict an organism's phenotype from its genome and environment and, in time, to design genomes for a desired function. The team works as one integrated computational and experimental group: experimentalists generate genetic variation and quantitative measurements at scale (growth and fitness, transcriptomics, proteomics, metabolomics), the models are trained and validated on that data, and the results shape the next round of experiments and insights. The experimental work is based in GBI's laboratories in the Oxford Science Park, alongside GBI's automation capability and in daily contact with the AI scientists in the AI & Robotics team. We are building a joint experimental computational team focussed on building, training and validating multi-modal biological models. The team will: i) generate experimental perturbation and measurement data at scale, ii) build multi-modal biological models and, iii) use the experimental data they generate to train and validate the multi-modal biological models they build. In this role you will: i) perform experimental genome engineering work to generate genetic variation at scale and/or ii) design and implement scalable biological measurement over one or more modalities. Where appropriate the work will leverage the substantial automation capability within the institute. Your work will be performed under the guidance of Jason Chin. You will be part of a single team composed of AI scientists and synthetic biologists working together. We are looking for colleagues with deep expertise in genome engineering and/or quantitative phenotyping of model bacterial species such as Escherichia coli. The role requires the ability and willingness to work as part of a cross-disciplinary team at the interface of computational and wetlab biology. Our team ethos is based on mutual learning, strong peer-to-peer support, and a deep sense of scientific curiosity and ambition. This is your opportunity to be part of cutting-edge research within an institute dedicated to engineering biology at an unprecedented scale. You will be leveraging GBI's exceptional facilities, sustained funding, and collaborative environment. You will design and execute experiments, contribute to high-impact publications, and play a key role in the training and mentorship of junior researchers and students. Working at the interface of biology, AI, technology, and engineering, you will help shape GBI's vision to reimagine what's possible in biology. • Design, execute, and troubleshoot experiments, including the development of novel methodologies and adaptation of existing techniques to new applications. In particular, the successful applicant will utilise genome engineering strategies in the lab to produce a diversity of microbial strains as the source of training and validation data in a high throughput fashion. In addition, they will also design and prototype a range of experimental measurement strategies for characterising these strains at scale, • Collaborate with other GBI scientists from other groups expert in synthetic biology, automation, bioinformatics, -omics and machine learning, and AI scientists from the AIR institute, as required., • Analyse complex datasets using computational and statistical tools, interpreting results in the context of broader research goals, • Contribute intellectually to the research direction by identifying opportunities for innovation and refining research questions, • Prepare and publish high-quality scientific papers, reports, presentations, and protocols, • Present research at national and international conferences, seminars, and internal meetings, • Collaborate with multidisciplinary teams within GBI, EIT, and external partners to advance complementary workstreams, • Build and maintain research infrastructure, laboratory capabilities, and cutting-edge technologies, • Mentor and support junior researchers, including PhD students and research assistants, • Translate research findings into commercial or translational opportunities in alignment with EIT's mission, • Identify and pursue opportunities for intellectual property generation and protection, • Ensure research activities comply with EIT's policies, legal requirements, and best scientific practice This list is not exhaustive and the role holder may be required to undertake additional tasks and duties commensurate with the role. • Completed a PhD in a relevant field (e.g., synthetic biology, computational biology and AI, microbial genomics, cell biology, genomics, robotics and automation, metabolomics, and proteomics.), • Track record of delivering ambitious research projects to a high standard, • Strong track record in research, ideally in molecular biology, synthetic biology, or related fields, • Skilled in data analysis and interpretation; experience with genomic analysis, automation, or computational tools desirable, • Proven ability to work independently, think creatively, and solve complex experimental problems, • Experience publishing in high-impact journals and presenting at international conferences, • Excellent organisational skills with the ability to manage multiple concurrent projects, • Strong written and verbal communication skills, with experience collaborating in multidisciplinary teams, • Capacity to build and sustain productive collaborations internally and externally, • Resilience, adaptability, and enthusiasm for working in a fast-paced, high-growth research environment, • Deep scientific curiosity and the drive to run ambitious experiments at scale, which can be used for the training and validating foundation models for the purpose of understanding and predicting an organism's phenotype from its genome and environment, • Basic familiarity with machine-learning concepts is welcome (what a model needs from data: coverage of the variable space, controls, replication, consistent metadata), • Annual Bonus, • Travel Allowance, • Enhanced sick pay, • Pension - Employer contribution 7.5%, minimum employee contribution 5%, • Life Assurance, • Income Protection, • Private Medical Insurance as standard for you, your partner and any dependents. Including hospital Cash Plan, • Employee discounts, • Electric car scheme, • Nursery Salary Sacrifice scheme, • Cycle to Work Scheme, • Family Planning, • Neurodiversity support including advise and assessments, • Coaching & Therapy services, • You must have the right to work permanently in the UK with a willingness to travel as necessary. In certain cases, we can consider sponsorship, and this will be assessed on a case-by-case basis, • You will live in, or within easy commuting distance of, Oxford (or be willing to relocate) #J-18808-Ljbffr

The Executive Director, Drug Metabolism & Pharmacokinetics, will lead the DMPK team at our Oxford site and will be part of the Global DMPK and Oxford Site leadership teams. The responsibilities of the role include developing and executing the strategy and operations of the Oxford DMPK team, as well as the scientific and managerial coordination of its groups and employees. This role will optimise interdisciplinary activities within DMPK and integrate activities with those of the other sites and departments, and thus, play a major role in shaping the direction of the overall Vertex portfolio. Using deep scientific expertise and strong leadership skills, this role will provide strategic and scientific direction to help advance the discovery and development of transformational therapies for serious unmet medical needs at Vertex. • Develop a strategy and vision for the Oxford DMPK team that is aligned with the Global DMPK and Vertex R&D vision/mission, • Develop and execute DMPK scientific strategies to address ADME challenges in discovery and development programs, • Build and maintain strong collaborative partnerships with Medicinal Chemistry, Biology, Preclinical Safety, Clinical Pharmacology, CMC and other R&D disciplines to advance Vertex programs through discovery and development., • Represent DMPK function on drug discovery and development teams, at the Oxford site and with Vertex governance bodies, • Implement innovative technologies and approaches to enhance scientific impact and/or efficiencies., • Provides scientific and managerial leadership to their team in prioritising and executing on key deliverables and project needs, • Ensure completion of necessary DMPK regulatory documentation and reports to support drug development, including Investigator Brochures, INDs (or equivalent), and marketing applications., • Hire, develop, manage and retain key talent to maintain a high-performing team., • Develop internal and external sourcing strategies and liaise across sites to best meet project needs. Contribute to developing Global DMPK resource allocation, staffing needs, expenses, and capital budgeting, as well as implementation plans., • Participate in the review of business development opportunities Strong management and leadership skills, with emphasis on developing and mentoring junior scientists to create a high-performing team Successful track record and experience in a DMPK lead role on multiple R&D teams across more than one therapeutic area. Extensive experience working with small molecules is a must. Additional expertise and familiarity with one or more other modalities (e.g., protein, antibody and nucleic acid therapeutics, cell and gene therapies) is desired. Deep scientific and strategic expertise in various components of DMPK science such as in vitro and in vivo ADME assays, mass spectrometry and bioanalysis, pharmacokinetic data analysis, biotransformation/disposition pathways, drug interaction risk assessment and human dose and drug interaction predictions. Additional skills in areas such as transporter science, enzymology and PK/PD and PBPK modelling will be a plus. Ability to critically evaluate and implement new science and technology as it relates to the discovery and development of new medicines Excellent verbal, written and interpersonal communication skills, and ability to develop and grow strong cross-site/function collaborations, Proven experience in a similar role is required after a PhD or the equivalent combination of education and experience. At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. On-Site DesignatedFlex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. #J-18808-Ljbffr

Senior Finance Manager - 12-Month Maternity Cover We’re looking for an experienced Senior Finance Manager to join Ryze Power in Oxford on a 12-month maternity cover, owning month-end, VAT, audit and cash forecasting for HydraB’s energy transition business. If you’ve seen it before, take pride in a clean balance sheet and are happy to take ownership and run with it, this one’s for you. The UK’s fleets are going zero-emission, and they need the energy to get there. Ryze Power provides it - supplying hydrogen, building EV charging infrastructure and delivering energy services for commercial fleet, industrial and public sector customers across the UK. From hydrogen bought and sold to infrastructure projects delivered on the ground, Ryze is where the transition to zero-emission transport becomes real. As part of HydraB Group, alongside businesses building the vehicles and hydrogen infrastructure behind that shift, Ryze brings it all together for the customer. Finance that keeps pace with that, with no surprises. This role owns that. This is a hands‑on, individual contributor role covering Ryze Power’s full reporting cycle - month-end close, balance sheet reconciliations, quarterly VAT, audit and cash flow forecasting. Reporting to the Finance Director, you’ll own Ryze Power’s results and sub-ledgers in Sage Intacct, while Group Finance manages consolidation and treasury. You’ll work closely with Ryze’s operations and sales teams, Group Finance and Legal. Support is there when you need it, but this role needs someone who can pick things up quickly and run with it from day one. It’s a full-time role, based fully on‑site in Oxford, 5 days a week. • Lead the monthly, quarterly and annual reporting cycle, producing accurate and timely management accounts, • Own month-end close and balance sheet reconciliations, keeping the control environment strong, • Prepare quarterly VAT returns and manage other statutory and tax filings, • Coordinate the external audit - auditor queries and year-end financial statements, • Manage cash flow forecasting and liquidity planning, working with Group Finance on treasury, • Get to grips with the commercials of the business - stock, fixed assets, project costs and revenue, and hydrogen bought and sold, • Keep Ryze Power’s sub-ledgers and intercompany balances accurate and reconciled ahead of Group consolidation, • Oversee invoicing, collections, credit control and supplier payments to keep working capital under control, • Ensure compliance with FRS 102, the Companies Act and Group accounting policies, including fixed asset accounting and capitalisation, • Spot and deliver improvements to finance processes, controls and reporting, • Are ACA, ACCA or CIMA qualified with 5+ years’ post-qualification experience, including time as a Finance Manager or similar, • Have owned month-end close, balance sheet reconciliations, VAT and audit hands‑on, • Know UK GAAP and FRS 102 well, and have worked in a group structure with intercompany and consolidation reporting, • Have experience in a growing SME, engineering, manufacturing or project-based environment, • Have advanced Excel skills and a high level of accuracy, • Are a natural problem solver who picks things up quickly and can run with it without close supervision, • Are proactive and keep people in the loop - no surprises, • Build good relationships with finance and non‑finance colleagues, and can explain the numbers clearly, • Experience in energy, hydrogen or infrastructure project accounting, • Pension - up to 8% employer contribution, • 25 days holiday + bank holidays, with buy & sell flexibility, • Life assurance - 4x basic salary, • Electric car salary sacrifice scheme, • Cycle to Work scheme, • Employee Assistance Programme - 24/7, 365 days Ryze Power is part of HydraB Group, pioneering the UK’s transition to net zero energy and transport - building the hydrogen and electric infrastructure that gets the sector to scale #J-18808-Ljbffr

the accountants fuelling ambitious businesses. We’re a full service, tech-enabled firm, working with entrepreneurs and businesses to help them achieve their goals, and make an impact in the world. We’re growing fast and are bringing like-minded advisors together to form a full-service tech-enabled accounting partner for thousands of SMEs. Our team use their incredible expertise alongside intuitive technology to help businesses and entrepreneurs plan better and grow faster. Our mission is to become the UK’s leading tech-enabled accounting firm for SMEs. We have ambitious goals and our high-calibre team work hard to achieve them. We are one team with one agenda, working collaboratively in a respectful environment to deliver a great service to our clients. So if you join us, you’ll not only be working on exciting client challenges, you’ll also be helping us shape the future of accounting. Join us in our Business Tax team and become an instrumental force in shaping our clients' financial success. Your role will encompass not only navigating client through the nuances of Business Tax Compliance with a view to also providing strategic advice across various Business Tax facets. This is your chance to shine and lead in a dynamic environment. Are you an accomplished Business Tax professional looking for a senior leadership role with the opportunity to influence and shape tax strategy? Join us as an Associate Director/Director in Business Tax, where you will take a lead in driving growth, advising high-profile clients, and delivering strategic insights. This is a senior position that offers the chance to make a significant impact both within the firm and for our clients. • Leadership of complex Business Tax engagements: You will lead the team in managing complex Business Tax engagements, overseeing the preparation and review of tax returns, and ensuring compliance with ever-changing legislation and regulations., • Strategic Tax Advisory: You will provide high-level tax advisory services, delivering strategic tax advice on business transactions and ensuring that our clients are always positioned to optimise their tax outcomes., • Business Development: You will play a key role in business development initiatives, including client pitches, writing thought leadership articles, and representing the firm at industry events. Collaborating with our marketing and sales teams, you will help drive growth in the Business Tax service line., • Team Leadership and Development: You will mentor and lead the Business Tax team, fostering a culture of learning and development. This includes providing training on the latest tax developments and ensuring that all team members are performing at their best., • Client Relationship Management: As a senior leader, you will nurture and manage relationships with key clients, ensuring their ongoing satisfaction and identifying opportunities for further collaboration. Your extensive experience in Corporate Tax within a leading Accountancy Practice has equipped you for this influential role. • CTA/ACA/ACCA qualified (or equivalent), with substantial post-qualification experience, • Have proven leadership experience, managing complex tax engagements and advising clients at a senior level, • Possess strong business development skills, with a track record of generating new business and deepening client relationships, • Are an effective communicator, able to influence and collaborate with stakeholders across all levels of the organisation, • Have outstanding project management skills, capable of overseeing multiple large-scale projects simultaneously, • Thrive in a hybrid-working environment, working effectively both remotely and in the office, while maintaining a strong connection with your team and clients When you join Gravita, we’ll support you on your own growth journey. We want to be the place you learn, grow and unlock your true potential. We’ll work with you to build a progression plan to outline how you’ll grow at our company and everything we’ll do to help you get there. We’re also passionate about learning and development, to help you focus on your future. • Our standard working week is a 37.5-hour week on a hybrid basis (with up to 50% of your time across the month home based and the other 50% office-based), • Core working hours are 10am - 4pm Monday to Friday, • Flexible working and happy employees are at the top of our list here at Gravita and we have been working hard to support our teams through the fast-paced changes., • Your development won’t be forgotten, our development support is extraordinary for a firm of our size., • It's a busy, fast-paced environment here at Gravita. Feel free to check out our social media channels (Instagram, X, LinkedIn and Glassdoor). #J-18808-Ljbffr

Manpower Recruitment has teamed up with an established education environment in Oxford and are looking for a Full Time Marketing Manager. This is a permanent full‑time position with a salary up to £45 k per annum depending on experience. This is an office‑based role, working Monday – Friday from 8:30 am – 5 pm (or 9 am – 5:30 pm) with one hour lunch break. The working time can be discussed further during the interview. Please note, with the environment closing for Christmas, interviews will be taken place early January 2026. Reporting to the Director of Admissions, the Marketing Manager will deliver effective marketing campaigns to recruit students into the environment, at all entry points for both day and boarding. In a dynamic role with both marketing and communications responsibilities, the Marketing Manager will implement the day‑to‑day marketing activities and create, research, and monitor content for marketing and communications material. The Marketing Manager will line up to manage the Marketing and Communication Executive and will be responsible for organising the activities within the marketing team, allocating tasks, and ensuring there is appropriate marketing support available when it is required. The Marketing Manager will work closely with the various marketing and communications teams. The Marketing Manager will work closely with our internal Admissions Manager & Admissions Team to monitor applications, student numbers and report on campaign lead quality. • Lead, develop and implement a cost‑effective, integrated marketing and communications plan to achieve recruitment targets and engage key stakeholders., • Drive initiatives to increase domestic and international enquiries, visits and applications in collaboration with the Admissions Team and the Global Recruitment Team (GRT) in the UK and abroad., • Lead and drive innovation in marketing strategy to strengthen future recruitment pipelines, identify new opportunities, implementing best practices, and developing solutions to emerging challenges., • Plan and deliver all marketing activities, including recruitment events, digital, social media, PR, email and print for both UK and international audiences., • Manage the annual marketing budget, ensuring accurate forecasting, reporting and KPI tracking; measure and optimise marketing performance, providing regular reports to the Principal and Director of Admissions & Marketing., • Maintain brand integrity, ensuring quality and consistency across all communications and materials., • Own and optimise the school’s website, ensuring regular updates and strong performance., • Support retention by creating and sharing engaging content about school life across multiple channels., • Build, engage and manage the school’s Alumni community., • Select and manage external agencies and suppliers to deliver effective marketing outcomes., • Support internal teams, Regional Managers and overseas partners by providing high‑quality marketing collateral., • Conduct ongoing market research to ensure competitiveness and inform strategic planning., • Excellent marketing strategic planning skills., • Excellent organisational and project management skills., • Strong interpersonal and stakeholder management skills – the Marketing Manager will be working with many people in and out of the school from students to senior managers., • Outstanding attention to detail and a high level of accuracy., • Flexibility and resilience – this is a fast moving, target driven, focused environment where priorities can change according to changes in recruitment patterns., • Excellent management skills, motivating and leading marketing across the school., • Digital marketing proficiency, including analysing data reports, social media management across a variety of channels, ability to create and run efficient paid advertising, efficient use of email marketing and social media tools., • Excellent copy writing, editing and grammar skills, with the ability to adapt style and create compelling messages accurately and effectively., • Excellent events management skills (including physical and online events)., • Develop a marketing strategy, marketing plan and content plan., • Copy writing and editing., • Advertising (creating both digital and print adverts and advertising plans)., • WordPress and analytics platforms such as Google Analytics., • Mailchimp email marketing campaigns., • Paid media and SEO., • Experience in the UK independent school sector. If interested, please get in contact with a Manpower Representative. #J-18808-Ljbffr

Job Summary: Responsible for leading and managing an independent research group within the Generative Biology Institute (“GBI”), delivering a program of bold, ambitious and transformational research which is broadly aligned with GBI’s vision of making biology engineerable and unlocking its potential for good Generative Biology Institute The vision of the GBI is to lay the foundations for engineering biology, and unlock its potential for good. To achieve this, we must overcome two key challenges. First, we need the ability to write in the natural language of biology, enabling the rapid and scalable synthesis of entire genomes with precision. Second, we must understand what to write, determining which DNA sequences will generate biological systems that perform the desired functions. Addressing these challenges will allow us to harness the full power of biology to create transformative solutions across health, agriculture, clean energy and more. Part of the Ellison Institute of Technology, Oxford (“EIT”), GBI is led by founding Director Jason Chin. It will house 30 groups and more than 500 researchers at scale, focused on solving the two critical challenges in making biology engineerable and applying the solutions to addressing the global challenges encapsulated in EIT’s Humane Endeavors. GBI will have sustained and substantial funding to support the unique scale and ambition of its ground-breaking vision for engineering biology. GBI researchers will also be supported by cutting edge facilities including mass spectrometry, flow cytometry, sequencing, automation, scientific computing, bioinformatics, and machine learning. GBI will also have access to substantial compute resources that can be leveraged to further accelerate progress. The environment at GBI will allow researchers to undertake ambitious, long-term, collaborative research, and we will actively support the translation of research to commercial applications, where appropriate. GBI will commence operations in 2025. The team will work from a purpose-made facility in the Oxford Science Park, currently under construction. Once complete, this state-of-the-art facility will include more than 40,000 m² of research laboratory and office space. Ahead of the launch of GBI in Q4 2025, we are now accepting applications for PrincipalInvestigator positions at all levels, including Senior PrincipalInvestigator (equivalent to Tenured Professor) and PrincipalInvestigator (equivalent to a Tenure-Track Professor) as we build a world-class faculty. We expect to make 5 or more appointments before the end of 2026, with further appointments in 2027 and 2028 as we scale. Ellison Institute of Technology, Oxford (“EIT”) EIT’s purpose is to have a global impact by fundamentally reimagining the way science and technology translate into end-to-end solutions and delivering these solutions in programs and platforms that respond to humanity’s most challenging problems. EIT is investing significant resources in a new world-class research and development facility in the Oxford Science Park, including GBI. EIT is committed to cultivating a community where excellence is achieved through collaboration, trust, innovation and tenacity. We foster an environment where everyone’s experience and expertise are valued. We are curious and resilient in our efforts to drive long-term, sustainable innovation to meet humanity’s most enduring challenges. Key Responsibilities: • To set the research direction for your group and ensuring research activity is consistent with that direction and directly relevant to GBI’s vision., • To recruit and manage a group of outstanding researchers, which may include postdocs, doctoral students (in partnership with the University of Oxford, we are establishing a doctoral programme in Generative Biology with up to 20 fully funded doctoral student positions per year), research assistants and other scientists., • To mentor highly promising early career researchers to achieve the group’s goals and progress their aligned career objectives., • To collaborate with other groups within GBI and with colleagues within the broader EIT family to deliver bold, ambitious and transformational research that would not be possible within an individual group., • To help shape the facilities in GBI as part of the scientific strategy for delivering GBI’s vision. Essential Knowledge, Skills and Experience: • A PhD in a relevant scientific discipline, such as synthetic biology, computational biology and AI, microbial, plant and human cell biology, genomics, robotics and automation, and nucleic acids chemistry., • A strong publication record in your field, demonstrating the ability to deliver bold, ambitious and transformational advances., • Track record of building and managing collaborations, both internally and with external academic and/or industry partners, to enhance research capabilities., • Strong communication and leadership skills, with the ability to engage with senior researchers, technical teams, and external stakeholders., • We welcome applications from researchers who have experience running their own group as a Professor, Associate Professor, or Assistant Professor, and from those seeking their first independent position., • We also actively encourage applications from those who have worked in an commercial setting, such as a biotech and companies leveraging AI for research., • Assessment of applicants with respect to knowledge skills and experience criteria will be calibrated for career stage. Our proposition for our PrincipalInvestigators: • Research groups will be supported by substantial core funding, for posts, consumables, and equipment matched to the needs of the project., • Additional posts can be made available to support specific research projects, particularly for ambitious collaborative projects across groups., • Group leaders will have the ability to also supervise graduate students and participate in the doctoral program in generative biology being established through the University of Oxford-EIT alliance., • Access to cutting-edge facilities and infrastructure, initially including mass-spectrometry, flow cytometry, imaging, automation and, sequencing, with intention to expand facilities, in line with GBI’s scientific strategy, as we scale., • Access to significant compute capacity and capability, including in partnership with EIT’s AI team., • Group leaders will be encouraged to publish work from their group., • Opportunity to translate research with commercial application into a separate company in partnership with GBI’s translational team and with financial and operational support from EIT., • Where appropriate, we will support applications for faculty appointments at Oxford University, building on the University of Oxford-EIT Alliance We offer the following benefits: • Globally competitive salary and bonus., • Pension and travel allowance., • Training and development opportunities., • Additional benefits including enhanced holiday pay, life assurance, income protection, private medical insurance, hospital cash plan, therapy services, perk box. Terms of Appointment: • You must be eligible to work in the UK with a willingness to travel as necessary. We are open to sponsoring employment visas for this role; however sponsorship is not available for all visa types or in all circumstances. Eligibility will be assessed on a case-by-case basis., • You must be based in, or within easy commuting distance of, Oxford., • During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of our work. Your application Please submit a CV (no more than 3 pages, including a list of up to ten key publications), and cover letter explaining why you would like to join GBI (no more than 2 pages) Please submit a proposal (no more than 5 pages) of the research that you would like to undertake at GBI covering: • The research questions that you would like answer over a 5-10 year period and how this relates to the vision of GBI., • How this relates to your previous work., • The challenges that you need to overcome and the resources that you would need in order to be successful., • How you would intend to partner with colleagues at GBI and with the broader EIT family. We are interested in all research that is consistent with GBI’s vision. Some relevant areas include: • Molecular and Cellular Design and Evolution., • Enzyme design., • Design of molecular assemblies and machines., • Experimental accelerated evolution., • Robotics, automation and autonomous labs., • Genome mining and informatics-based discovery., • Computational AI sequence to function., • Modelling and building genetic and cellular circuits., • Cellular design., • Expanding chemistry in biology., • Nitrogen fixation., • Carbon fixation., • Programming cellular assemblies and synthetic tissues., • Scalable error free DNA and genome synthesis., • Microbial Genome Synthesis and Design., • Gb-scale Genome Synthesis for plants, human cells and animals., • Combinatorial synthetic genomics., • DNA delivery., • Predictive models of DNA sequence to function, at the scale of genes and genomes., • Human health applications and delivery mechanisms. We will be recruiting PrincipalInvestigators over the next 2–3 years, with applications reviewed every one to six months as part of a rolling selection process. #J-18808-Ljbffr

Ellison Institute of Technology and Chemistry Research Laboratory, Oxford Applications are invited for a Senior Project Manager to support delivery of the Wellcome Synthetic Human Genome (SynHG) programme, a five-year, £10 million multi-centre research initiative led by Professor Jason Chin and funded by the Wellcome Trust. The SynHG programme aims to develop the foundational and scalable tools, technology and methods needed to synthesise large sections of human genomes/chromosomes. Through programmable synthesis of genetic material the aim is to unlock a deeper understanding of life, leading to potential acceleration of the development of safe, targeted, cell‑based therapies, and opening entire new fields of research in human health. The project aims to achieve reliable genome design and synthesis – engineering cells to have specific functions – which will be a major milestone in modern biology. The programme is also supported by a dedicated social science research strand that will explore the societal and ethical implications of synthetic human genome research. The programme is delivered through a partnership between the University of Oxford and the Generative Biology Institute (GBI), part of the Ellison Institute of Technology (EIT), where Professor Chin serves as Founding Director. SynHG brings together a multidisciplinary consortium of researchers from the University of Oxford, the University of Manchester, Imperial College London, the MRC Laboratory of Molecular Biology, and the University of Kent. The Senior Project Manager will play a pivotal role in the planning, coordination, and delivery of the Wellcome SynHG programme across all sites. The successful candidate will work closely with Professor Chin and the programme's co-investigators: Professor Patrick Cai (University of Manchester), Professor Tom Ellis (Imperial College London), Dr Julian Sale (MRC Laboratory of Molecular Biology, Cambridge), and Professor Joy Zhang (University of Kent), to oversee programme planning, milestone tracking, governance processes, budget monitoring, risk management, and funder reporting to ensure delivery of programme objectives on time and within budget. The role will involve coordinating activities across multiple institutions and workstreams, maintaining programme plans and reporting frameworks, supporting governance committees and advisory boards, and providing high-quality analysis and reporting to support decision‑making by programme leadership. This is an exciting opportunity to contribute to a pioneering scientific initiative at the front‑end of genome engineering and synthetic biology. Find out more about SynHG at: Find out more about the GBI at: Applicants should hold a degree‑level qualification, or possess equivalent professional experience, in project management, science, engineering, life sciences, or a related discipline. You will have experience managing complex projects or programmes involving multiple stakeholders, institutions, and workstreams. Experience supporting large-scale research programmes, scientific collaborations, or externally funded projects is highly desirable. The successful candidate will demonstrate excellent organisational and communication skills, strong attention to detail, and the ability to manage competing priorities in a fast‑paced environment. You will be comfortable working with senior academic leaders, researchers, operational teams, and external partners, and will have experience of budget monitoring, risk management, reporting, and stakeholder engagement. Experience of working within a university, research institute, or scientific innovation environment would be advantageous, as would familiarity with major research funders and multidisciplinary research programmes. Experience working in the field of synthetic biology, engineering biology, or molecular biology is highly desirable. The post‑holder will spend the majority of time in Oxford, and will also be expected to spend time at the other institutions. #J-18808-Ljbffr

Ellison Institute of Technology and Chemistry Research Laboratory, Oxford Applications are invited for a Senior Project Manager to support delivery of the Wellcome Synthetic Human Genome (SynHG) programme, a five-year, £10 million multi-centre research initiative led by Professor Jason Chin and funded by the Wellcome Trust. The SynHG programme aims to develop the foundational and scalable tools, technology and methods needed to synthesise large sections of human genomes/chromosomes. Through programmable synthesis of genetic material the aim is to unlock a deeper understanding of life, leading to potential acceleration of the development of safe, targeted, cell‑based therapies, and opening entire new fields of research in human health. The project aims to achieve reliable genome design and synthesis – engineering cells to have specific functions – which will be a major milestone in modern biology. The programme is also supported by a dedicated social science research strand that will explore the societal and ethical implications of synthetic human genome research. The programme is delivered through a partnership between the University of Oxford and the Generative Biology Institute (GBI), part of the Ellison Institute of Technology (EIT), where Professor Chin serves as Founding Director. SynHG brings together a multidisciplinary consortium of researchers from the University of Oxford, the University of Manchester, Imperial College London, the MRC Laboratory of Molecular Biology, and the University of Kent. The Senior Project Manager will play a pivotal role in the planning, coordination, and delivery of the Wellcome SynHG programme across all sites. The successful candidate will work closely with Professor Chin and the programme's co-investigators: Professor Patrick Cai (University of Manchester), Professor Tom Ellis (Imperial College London), Dr Julian Sale (MRC Laboratory of Molecular Biology, Cambridge), and Professor Joy Zhang (University of Kent), to oversee programme planning, milestone tracking, governance processes, budget monitoring, risk management, and funder reporting to ensure delivery of programme objectives on time and within budget. The role will involve coordinating activities across multiple institutions and workstreams, maintaining programme plans and reporting frameworks, supporting governance committees and advisory boards, and providing high-quality analysis and reporting to support decision‑making by programme leadership. This is an exciting opportunity to contribute to a pioneering scientific initiative at the front‑end of genome engineering and synthetic biology. Find out more about SynHG at: Find out more about the GBI at: Applicants should hold a degree‑level qualification, or possess equivalent professional experience, in project management, science, engineering, life sciences, or a related discipline. You will have experience managing complex projects or programmes involving multiple stakeholders, institutions, and workstreams. Experience supporting large-scale research programmes, scientific collaborations, or externally funded projects is highly desirable. The successful candidate will demonstrate excellent organisational and communication skills, strong attention to detail, and the ability to manage competing priorities in a fast‑paced environment. You will be comfortable working with senior academic leaders, researchers, operational teams, and external partners, and will have experience of budget monitoring, risk management, reporting, and stakeholder engagement. Experience of working within a university, research institute, or scientific innovation environment would be advantageous, as would familiarity with major research funders and multidisciplinary research programmes. Experience working in the field of synthetic biology, engineering biology, or molecular biology is highly desirable. The post‑holder will spend the majority of time in Oxford, and will also be expected to spend time at the other institutions. #J-18808-Ljbffr

Ryze Power, part of HydraB Group, is seeking a Senior Finance Manager for a 12-month maternity cover in Oxford. You will own the full reporting cycle, including month-end close, VAT, audit and cash forecasting, reporting to the Finance Director and coordinating with Group Finance. This hands-on role requires strong UK GAAP knowledge, 5+ years post-qualification, and experience with a growing SME in energy or project-based environments. On-site, 5 days a week in Oxford. #J-18808-Ljbffr

Oxford Engineering is looking for a Quality Engineer to deliver professional quality engineering service to the business with primary focus on Manufacturing Quality Control requirements. • A minimum of five years recent experience as a Quality Engineer or equivalent related function., • PC literate with competence in Microsoft Office., • Ability to train employees in quality related subjects., • Sound knowledge of inspection techniques, including:, • The ability to interpret complex mechanical engineering drawings and determine appropriate measuring techniques., • The ability to produce credible inspection and associated reports., • Good project management and liaising regularly with both customers and suppliers., • Mechanical Engineering Apprenticeship., • Good knowledge of programming CMMs, supported by a certificate of competence in CMM programming issued by the CMM manufacturer or agent. PC-DMIS programming ability., • CMM: Hexagon S Chrome with tactile & laser heads, • ISO 9000 Auditor Qualification, • Liaising with Customers and Suppliers on quality related issues, • Manufacturing liaison and reporting shortfalls to Manufacturing supervision., • Training Operators in all aspects of inspection techniques and equipment. Including the preparation of inspection equipment work instruction., • Assisting in effective management of the entire measurement and test equipment calibration system., • Setting of adjustable M&TE for use by Manufacturing Operators., • Recommending and pursuing (when sanctioned) improvements to both Inspection and Quality techniques and equipment., • Translation of Customer quality requirements into detailed Manufacturing instructions., • Compiling routine final inspection trend analysis and reports., • Compilation of Inspection report blanks., • Managing Non-Conformances and Customer Complaints through 8Ds/5Whys, • Compilation and submission of various Customer documentation packs, • System and process audits up to completion as scheduled., • Supplier audits including reporting and recommendations., • Creation of Quality Control Plans/LTQRS on specific customer projects., • Other related duties as determined by Operations Director (In addition to the annually defined Departmental KPIs) • No parts waiting final inspection for longer than 24 hours., • Completion of audits as scheduled, • Reporting to Operations Director, • Role type:Permanent Position, • Holidays:23 days per annum + 8 Bank Holidays, • Pension:4% Matched Scheme –After Probation #J-18808-Ljbffr

We are seeking an experienced and highly motivated Project Controls Directorto lead the planning and scheduling discipline across a portfolio of major programmes and projects. As an Associate Director, you will provide strategic leadership across planning and project controls functions, working clos

An established international environmental advisory firm is seeking senior hires (Director and Principal level) into its Project Finance practice. The roles require leading lender-facing ESIA / ESDD for complex international projects, focusing on financing and investment decisions.

Are you ready to architect enterprise-grade Tax and Treasury data models in SAP S/4HANA that power real-time decisions and ensure compliance at global scale? This role shapes the data foundations that enable precise tax reporting, resilient treasury operations and confident financial stewardship, ul

Partnering with Program Directors and the Philanthropic Partnerships Director to ensure accurate forecast inputs, clear review of the actual spend and ongoing uplift of the financial literacy across the organisation. Director of Finance | $150K-$180K | Remote (US/UK/EU). Flexibility, with the abilit

Oversee and/or participate in the project development process working with Sponsors and functional Directors to negotiate and deliver quality product(s), assessing resource and financial and safety requirements, assigning resources, overseeing trial conduct, information, and data confidentiality, an

Turner & Townsend seeks an experienced Associate Director to lead Planning and Project Controls across a portfolio of major programmes.

An international non-profit organization seeks a Director of Finance to lead financial operations and embed sustainability into decision-making. Responsibilities include overseeing investment decisions and partnering with program directors.

Define and align program-level vendor strategies in partnership with Clinical Operational Program Heads, Portfolio Innovation Directors, Procurement, and alliance stakeholders. Excellent communication, planning, project management, analytical, and problem-solving capabilities. We are seeking an expe