Data scientist jobs in Boston, MassachusettsCreate job alerts

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s ___ and ___. I further attest that all information I submit in my employment application is true to the best of my knowledge. Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Vice President , Global Clinical Lead - Solid Tumor in our Cambridge office. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Here, you will be a vital contributor to our inspiring, bold mission. OBJECTIVES: Responsible for leading as the Global Clinical Lead a large solid tumor oncology franchise that encompass multiple late stage and early phase programs . Ensures ongoing review and agreement of the Therapy Area Strategy and associated documents formulated by the OTAU leader prior to their review and approval by appropriate governance committees. Oversees the development and execution of the Integrated Disease Area Strategy (IDAS) and overall Integrated Global Development Plan (IGDP). Responsible for review of synopses, other relevant clinical study documents and critical Study Results. Provide leadership and oversight of specific OTAU related programs and if applicable other indication specific clinical leads. Responsible for providing guidance to TA leaders on regional specificities within Therapeutic Area. ACCOUNTABILITIES: • Clinical Development team participation and leadership, • Accountable to Oncology Clinical Science Head to provide strategic clinical input on assigned clinical studies., • Consistent with the Takeda R&D Oncology Therapeutic Area Unit strategy, goals and objectives, this leader will partner with the other key functions and leaders and members of Oncology Precision and Translational Medicine, Oncology Portfolio Strategy Group, Global Regulatory Affairs, Quantitative and Clinical Pharmacology, other R&D Functional Line Oncology Therapeutic Area Leads, Global Product Launch Strategy Oncology Franchise Leads, Regional Oncology Franchise Leads, Oncology Drug Development Unit (DDU) and other Oncology extended leadership, to drive the alignment on global clinical research and development strategy as related to internal and external pipeline and non-pipeline initiatives for the Takeda R&D Oncology Community across all regions, • Part of the Oncology Clinical Sciences Leadership Team providing key input in strategic planning and connectivity for the overall Oncology Clinical Sciences group, • Leads the Global Development Team (US, EU, and others) managing both the US/EU Development Team and the Japan/ China Development team for assigned compounds. In some cases may lead the US/EU Development Team but more likely will oversee the study physician and/or clinical scientist leads responsible for leading the team. Emphasis will be on insuring that the development teams are proactively identifying contingencies, potential risks and strategies to address future obstacles., • Directs Development Team strategy and deliverables overseeing the Development Strategy, Clinical Development Plan and Clinical Protocols. Recommends scope, complexity and size, which influence the budget of all aspects of a program. Provides continual critical evaluation of the development strategy to maintain a state-of-the-art development plan that is competitive and consistent with the latest regulatory requirements, proactive identification of challenges, and development of contingency plans to meet them., • Responsible for high impact global decisions: interpreting data from ongoing internal and external studies, assessing the medical and scientific implications and making recommendations that impact regional and global development such as “go/no go” decisions or modification of development plans or study designs that may have a significant impact on timelines or product labeling. Plans clinical development strategies in context of medical/clinical significance considering how a given product will fit in with current treatments, standard of care, and unmet medical need., • Accountable for ensuring regional strategies and trade-offs in regional requirements are well articulated in the global strategy documentation and that stakeholders are appropriately briefed., • Providing strategic input into global development strategies and plans for all compounds in OTAU., • Providing clinical and strategic support to evaluation of external compounds (alliances and in-licensing opportunities), • Primary interface with Medical Affairs team for strategy and to support of product commercial efforts, • Contributing to the creation and maintenance of regional KOL network, • Providing recommendations for GDT leader nominations and reviewers of external compounds as part of business development efforts, • Liaison with Clinical Operations and Project Management for co-ordination of logistics study planning and implementation, • Synopsis / Protocol Development, Study Execution, & Study Interpretation, • Consistent with membership of the Clinical Review Board Committee, responsible for critical review of synopses, protocols, IBs and relevant clinical documents relating to studies in assigned compounds., • Trial Medical Monitoring, • Reviews and assesses overall safety information in conjunction with Pharmacovigilance and Medical Monitor of record for assigned compounds., • External Interactions, • Oversees and leads all clinical science activities involved in interactions with FDA, other regulatory agencies and key opinion leaders relevant to assigned compounds., • Responsible for evaluation of external interactions in the context of overall development strategies using complex problem solving in the region but in context of a global environment., • Proactive identification of challenges and development of contingency plans as appropriate., • Due Diligence, Business Development and Alliance Projects, • Responsible for evaluation of potential business development opportunities in the region but with the context of a global environment., • Conducts due diligence evaluations, of clinical development plans for potential alliances and or in-licensing opportunities., • Serves as clinical contact point for ongoing alliance projects and interface with partner to achieve Takeda’s strategic goals while striving to maintain good working relationship between Takeda and partner., • Assigns and manages clinical science staff who are involved in many of these activities., • Leadership, Task Force Participation, Upper Management Accountability, • Interacts directly with research division based on pertinent clinical and development expertise and in all aspects relating to assigned compound in regional area. Leads TGRD internal teams and global cross-functional teams. Works with functional leadership to prioritize projects within the therapeutic area., • Hires, manages, mentors, motivates, empowers, develops and retains staff to support assigned activities. Conducts performance reviews and drive goal setting and development planning. EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS: Experience • MD or combined MD/PhD or internationally recognized equivalent with minimum 15 years pharmaceutical research experience, including minimum 10 years late phase clinical development experience with a focus on medical oncology, • Clinical Training and Clinical Experience in Hematology/Oncology and/or Medical Oncology especially in solid tumor malignancies, • Strong depth of scientific and clinical understanding and experience in cancer biology especially in immune based therapies., • Experience in conducting and/ or leading multiple clinical trials involving immune based therapies, • Proven experience in successfully leading and supervising direct reports including several physicians, physician scientists, scientists within a clinical development team in a global matrix environment., • Demonstrated ability to foster a high-performance culture and build organizational capabilities., • Strong leadership commitment to diversity, equity and inclusion, with experience in creating an inclusive and collaborative team environment that leverages diverse perspectives., • Previous experience in successfully leading several clinical development team/matrix team with responsibility for Global studies in multiple regions. Clinical Development experience beyond US/EU, • Solid and Multiple experience in preparing and interacting with multiple regulatory agencies including FDA, EMA, and others, • Multiple NDA/MAA submission experience, • Proven ability to lead and manage highly trained medical, scientific, and technical professionals., • Superior communication, strategic, interpersonal and negotiating skills, • Enterprise level leadership with the ability to inspire, motivate and drive results, • Excellent communication both verbally and in writing and influencing skills, with the ability to engage, inspire, and influence stakeholders at all levels, including executive management and external partners., • Ability to proactively predict issues and solve problems, • Ability to drive decision-making within a multi-disciplinary, multi-regional, matrix teams, • Diplomacy and positive influencing abilities across multinational business cultures TRAVEL REQUIREMENTS: • Willingness to travel to various meetings or client sites, including overnight trips. Several international travels may be required., • Requires approximately 25-35 % travel. Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy. #LI-JT1 Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $307,300.00 - $482,900.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Boston, MA Employee Regular Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Our client, a leading organization in the biopharmaceutical industry, is seeking a dedicated and detail-oriented Bench Scientist to join their team. As a Bench Scientist, you will be an integral part of the Molecular Assessment and Profiling group within BioMedicine Design, supporting innovative biotherapeutic development efforts. The ideal candidate will demonstrate strong analytical skills, a passion for scientific discovery, and a commitment to advancing healthcare solutions, which will align successfully within the organization. Job Title: Bench Scientist Location: Cambridge, MA What's the Job? • Independently perform physicochemical, thermal, and colloidal stability assessments of biotherapeutic candidates using established assays, • Critically analyze and interpret experimental data to support the selection of lead biotherapeutic molecules, • Contribute to process improvements aimed at increasing efficiency and throughput within the group, • Accurately document experimental procedures, results, and analyses in electronic notebooks, • BA/BS with 5+ years or MS with 3+ years of relevant experience in biochemistry, biophysics, or related discipline, • Good understanding of protein biochemistry and stability, • Familiarity with protein characterization methods and analytical techniques such as aSEC, DSC, CGE, cIEF, and DLS, • Strong attention to detail with the ability to multitask efficiently, • Opportunity to contribute to impactful biotherapeutic research and development, • Hands-on technical development and scientific growth, • Collaborative and innovative work environment, • Supportive team dedicated to advancing healthcare solutions, • Medical and Prescription Drug Plans, • Dental Plan, • Vision Plan, • Health Savings Account, • Health Flexible Spending Account, • Dependent Care Flexible Spending Account, • Supplemental Life Insurance, • Short Term and Long Term Disability Insurance, • Business Travel Insurance, • 401(k), Plus Match About ManpowerGroup, Parent Company of: Manpower, Experis, Talent Solutions, and Jefferson Wells. ManpowerGroup® (NYSE: MAN), the leading global workforce solutions company, helps organizations transform in a fast-changing world of work by sourcing, assessing, developing, and managing the talent that enables them to win. We develop innovative solutions for hundreds of thousands of organizations every year, providing them with skilled talent while finding meaningful, sustainable employment for millions of people across a wide range of industries and skills. Our expert family of brands – Manpower, Experis, Talent Solutions, and Jefferson Wells – creates substantial value for candidates and clients across more than 75 countries and territories and has done so for over 70 years. We are recognized consistently for our diversity - as a best place to work for Women, Inclusion, Equality and Disability and in 2023 ManpowerGroup was named one of the World's Most Ethical Companies for the 14th year - all confirming our position as the brand of choice for in-demand talent.

Soils Scientist / $80k-$120k + INSANE BONUS STRUCTURE / Great Work Culture, Benefits, and MORE! This Jobot Job is hosted by: Kevin Finlay Are you a fit? Easy Apply now by clicking the "Apply" button and sending us your resume. Salary: $80,000 - $120,000 per year A bit about us: We are a civil engineering consulting firm providing Civil Engineering, Land Surveying, Land Planning and Landscape Architecture services to clients. We have received several awards & recognition over the years and have exciting designs we have created for our clients. Projects/clients include design for Single Home and Multi-Family Residential Developments, Commercial, Industrial, Medical and Education properties. Services: • Civil Engineering, • Boundary & Topographical Surveys, • ALTA Surveys, • Subdivision Plans, • Roadway Construction Surveys, • FEMA, LOMA & LOMR Documentation & Filing, • Elevation Certificates, • Design Layouts, • Landscape Architectural Design Services, • Landscape Plans, • Decentralized Wastewater Designs – STEP Systems, • Advanced Wastewater Designs, • Transportation Engineering, • Hydrologic Determinations Why join us? We offer an excellent benefits package that has been designed to meet the needs of our diverse workforce. Our package provides employees a consistent, competitive level of benefits with the flexibility to support individual growth within the organization. • Competitive Base Salary + STRONG BONUS STRUCTURE; Lucrative bonus structure!, • Full Benefits (Medical, Dental, Vision); Generous PTO, Vacation, Sick, and Holidays!, • Opportunities for growth and advancement, • Awesome culture! Job Details The Soil Scientist conducts detailed site evaluations to support septic system design and land development projects. This role involves performing field investigations, excavating and examining test pits, classifying soils in accordance with state and local guidelines, and preparing accurate soil maps and reports. The Soil Scientist collaborates with civil engineers, environmental specialists, and regulatory agencies to ensure site designs meet environmental and public health standards. This position requires extensive fieldwork, technical expertise in soil morphology and classification, and a strong understanding of onsite wastewater treatment regulations. Interested in hearing more? Easy Apply now by clicking the "Apply" button. Jobot is an Equal Opportunity Employer. We provide an inclusive work environment that celebrates diversity and all qualified candidates receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, age (40 and over), disability, military status, genetic information or any other basis protected by applicable federal, state, or local laws. Jobot also prohibits harassment of applicants or employees based on any of these protected categories. It is Jobot’s policy to comply with all applicable federal, state and local laws respecting consideration of unemployment status in making hiring decisions. Sometimes Jobot is required to perform background checks with your authorization. Jobot will consider qualified candidates with criminal histories in a manner consistent with any applicable federal, state, or local law regarding criminal backgrounds, including but not limited to the Los Angeles Fair Chance Initiative for Hiring and the San Francisco Fair Chance Ordinance. Information collected and processed as part of your Jobot candidate profile, and any job applications, resumes, or other information you choose to submit is subject to Jobot's Privacy Policy, as well as the Jobot California Worker Privacy Notice and Jobot Notice Regarding Automated Employment Decision Tools which are available at jobot.com/legal. By applying for this job, you agree to receive calls, AI-generated calls, text messages, or emails from Jobot, and/or its agents and contracted partners. Frequency varies for text messages. Message and data rates may apply. Carriers are not liable for delayed or undelivered messages. You can reply STOP to cancel and HELP for help. You can access our privacy policy here: jobot.com/privacy-policy

Job Description Summary Senior Principal Scientist / Associate Director, PK Sciences, Therapeutic Areas (DUAL LEVEL POSTING) #LI_Hybrid Location: Cambridge, MA or San Diego (US) We are seeking an enthusiastic and motivated PK Sciences project team representative to develop and implement translational or clinical pharmacology strategies to support the pursuit of transformative new medicines through late clinical development. Our unique organizational structure enables colleagues to work seamlessly in the translational and/or clinical space, offering opportunities for development and bench-to-bedside-to-bench translation. Experience in late discovery and/or clinical area is preferred. The scope of the role potentially includes small molecules, biologics/therapeutic proteins, antibody drug-conjugates, radioligand therapies and/or cell therapies across major therapeutic areas in Novartis, including oncology, immunology, cardiovascular renal metabolism, neuroscience, and global health. This position drives close interdisciplinary collaboration among the PK Science disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), and Operations through PK science sub-teams to achieve a holistic and integrative perspective of the ADME/clinical pharmacology properties of candidates and drugs Job Description Key Responsibilities: • Independently represent the PK Sciences function in cross-functional project teams, interactions with stakeholders within the organization and interactions with regulatory agencies, as appropriate, • Lead a PK Science Subteam with interdisciplinary representation of the major functions from within PK Science and beyond, • Ensures implementation of project strategies and monitors timelines, objectives, and budgets for assigned projects, • Present projects at various institutional review and approval boards, • Proactively contributes to developing drug candidates across Research Development and Commercial continuum, providing expert pharmacokinetic / drug metabolism and clinical pharmacology input, • Develop and execute clinical pharmacology strategies, including input into nonclinical and clinical study design, and analyzing PK and PK/PD data, to support compound development from discovery through late development, • Provide PK, dosage, PK/PD and M&S component of study protocols, reports, project summaries and development plans, and author pharmacokinetic/clinical pharmacology/biopharmaceutics sections/radiation dosimetry of IND/IMPDs and NDA/BLAs as well as prepare appropriate responses to global Health Authority questions, • Use of Artificial intelligence (AI) / Machine Learning (ML) approaches to enable model guided molecular design, preclinical and clinical data automation, authoring regulatory documents, and the use of predictive models, • Is a mentor to or manages junior associates in the organization This role reports to Therapeutic Area Head in PK Sciences within Translational Medicine (TM) in Biomedical Research. PKS is a global organization situated within Translational Medicine (TM), the clinical research arm of Biomedical Research within Novartis. PK Sciences plays a pivotal role in bringing innovative medicines to patients, by building on research advances to develop new therapies, bridging drug discovery and clinical application. PK Science is an enterprise-wide organization, working across both Biomedical Research and the Development organizations to advance the scientific knowledge of pharmacokinetics, metabolism and clinical pharmacology. Essential Requirements: • Ph.D. / Pharm.D. with relevant experience, • Preferred candidates will have a minimum of 5+ yrs at the Senior Principal Scientist Level and 8+ years at the Associate Director level) in clinical pharmacology, drug metabolism and pharmacokinetics or a related background in an industry setting., • Extensive and in-depth knowledge of pharmacokinetics including, drug metabolism and PK/PD evaluation, experience in working in project teams (preferably global) as well as sound awareness of recent developments in drug development and regulatory sciences., • Demonstrated success in working in a cross-functional, matrixed, project-team environment., • An influential Team player and talented negotiator with strong oral and written communication skills., • Proven record of mentorship and/or people management Desirable Requirements: • Hands-on project experience with Artificial intelligence (AI) / Machine Learning (ML) approaches is a plus Leadership / Novartis Behaviors in Action • Delivers results through disciplined execution, continuous improvement, and a strong focus on value and outcomes., • Demonstrates an enterprise mindset and strong ownership by prioritizing resources and decisions for maximum Novartis and patient impact., • Role models Novartis leadership behaviors through visible actions, continuous self reflection, and openness to feedback, • Builds trust through transparent communication, clear accountability, and consistent delivery against commitments., • Empowers others to innovate and improve while maintaining high scientific, ethical, and operational standards. AI fluency: • Brings strong AI and digital fluency, using enterprise tools to enhance insight generation, decision making, and team productivity., • Accountable for the ethical, transparent, and compliant use of AI in line with Novartis AI governance and data protection standards. External eminence: • Acts as an external thought leader, advancing Novartis' reputation in translational science and innovation. Operational excellence: • Drives operational excellence through disciplined execution, continuous improvement, and effective use of resources to maximize PKS and enterprise value., • Acts as a responsible steward of people, data, and digital capabilities, leveraging AI and automation to improve efficiency, quality, and decision speed. This is a dual posting. The final level & title of the offer role would be determined by the hiring team based on the skills, experience & capabilities required to perform the role at the level the role has been offered. The salary for this position is expected to range between: Senior Principal Scientist: $138,600 and $257,400 per year. Associate Director: $145,600 and $270,400 per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click here. EEO Statement: The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility and reasonable accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Salary Range $138,600.00 - $257,400.00 Skills Desired Chemistry, Clinical Pharmacology, Clinical Research, Clinical Study Reports, Clinical Trials, Data Entry, Drug Discovery, Due Diligence, Electronic Components, Gene Therapy, Lifesciences, Medical Research, Microsoft Office, Modeling And Simulation, Patient Care, Physics, Translational Medicine, Waterfall Model

R&D Partners is seeking to hire an Associate Scientist II in Cambridge, MA. Your main responsibilities as an Associate Scientist II: · Support process development, optimization, and scale-up of bioconjuagtion processes. · Support oligonucleotide synthesis method development, optimization and scale-up · Execute laboratory-scale processes to support research and in-house material needs · Perform routine in-process analytical tests (e.g., pH, conductivity, UV, basic chromatography) · Assist in process development for novel chemistries What we are looking for in an Associate Scientist II: · BS in Chemistry, Chemical Engineering, Biochemistry, or a related scientific discipline. · 0-2 years of laboratory experience (academic, co-op, internship, or industrial experience acceptable). · Oligonucleotide experience required. · Experiece with Bioconjugation, anitbodies, and peptides highly preferred. · Familiarity with analytical techniques such as pH, conductivity, HPLC, or LC-MS is preferred. Why Choose R&D Partners? As an employee, you have access to a comprehensive benefits package including: • Medical insurance - PPO, HMO &, • Dental & Vision insurance, • 401k plan, • Employee Assistance Program, • Long-term disability, • Weekly payroll, • Expense reimbursement, • Online timecard approval Pay Scale: $74,314 - $92,906 Dependent on Experience) R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies. R&D Partners is an equal-opportunity employer. If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists visit the 'Contact Us' page. R&D Partners is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. R&D Partners is acting as an Employment Agency in relation to this vacancy. By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data -

About the Role We are seeking a highly motivated Research Scientist to support cutting-edge work at the intersection of AI, machine learning, and biologics discovery. This role focuses on building scalable, data-driven modeling frameworks to accelerate therapeutic design across oligonucleotides and biologic modalities. You will play a key role in advancing AI/ML-assisted discovery pipelines, helping drive innovation in sequence-based modeling, antibody design, and next-generation therapeutics. Location: Open to Remote, within 1 hour of the Cambridge, MA 02142. What You’ll Do • Develop and implement advanced AI/ML models for antibody discovery, including generative protein design and protein language models, • Build and scale machine learning approaches for multi-objective optimization across biologic modalities, • Design sequence-aware predictive models to support oligonucleotide therapeutic development, including exon skipping response, • Create end-to-end computational frameworks covering data ingestion, feature engineering, model training, validation, and deployment, • Curate and integrate diverse datasets, including literature-based and experimental data, • Define and engineer key biological features such as sequence motifs, thermodynamics, and structural attributes, • Establish model benchmarks and collaborate with experimental teams to validate predictions, • Evaluate and integrate new tools and technologies to enhance modeling workflows, • Maintain clean, well-documented codebases and provide guidance to cross-functional teams What We’re Looking For • PhD in Computational Biology, Computational Chemistry, Machine Learning, Biomedical Engineering, or a related field, • 3+ years of relevant experience in industry or highly applicable post-PhD academic research, • Strong background in oligonucleotide chemistry and/or antibody design and characterization, • Experience modeling antibody-antigen interactions, including sequence and structural analysis, • Hands-on expertise with machine learning and deep learning methods such as RNNs, GNNs, Transformers, and generative models, • Proficiency in Python, R, and SQL, along with frameworks like PyTorch, TensorFlow, scikit-learn, or JAX, • Experience working with DNA, RNA, and protein modeling, including structure prediction and design, • Familiarity with cloud platforms, large-scale computing, and data infrastructure tools such as AWS, Docker, GitHub, or GitLab, • Strong communication skills and ability to collaborate across multidisciplinary teams Nice to Have • Experience working in cross-modality therapeutic design (e.g., biologics and oligonucleotides), • Exposure to production-level ML systems and scalable pipelines Why Join • Work on impactful, next-generation therapeutic technologies, • Collaborate with a highly interdisciplinary team of scientists and engineers, • Opportunity to contribute to innovative AI-driven drug discovery programs, • Flexible consideration for strong candidates from academic backgrounds Interested? Apply now to learn more.

APX Life Sciences are partnering with a leading biopharma company to find a PV Scientist to support their robust portfolio of both investigational and marketed products. This is a hands-on role where you'll own the science behind the safety data—leading aggregate reports, supporting signal detection, and partnering closely with safety physicians on regulatory responses, IB updates, and DSMB prep. Key Requirements: • 5+ years experience in a hands on PV Scientist role., • Strong background in aggregate report authoring (PSURs, PADERs, DSURs), • Comfortable with MedDRA, Argus, and Excel/PPT, • Ability to work independently and lead projects, • Advanced degree (PharmD, RN, PhD, MPH, NP) strongly preferred A fantastic role for a scientifically driven safety scientist to have real ownership of key deliverables, exposure to governance meetings, and the chance to mentor junior team members. 📍 60% in Boston 💰 Competitive package Reach out to Luis Berkane via LinkedIn or at to hear more. Also, do not hesitate to gently follow up! My inbox is active and I am not ignoring you :)

Scientist/Senior Scientist – Cell Biology (Diabetes) Company Overview GC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor George Church’s lab, a pioneer in synthetic biology, and allows for the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency and speed. GC Therapeutics is based in Cambridge, MA. For additional information, please visit ___ Job Purpose GC Therapeutics is seeking a highly motivated Scientist or Senior Scientist for its diabetes program. This role focuses on conducting genetic screens to identify factors that drive iPSC differentiation into therapeutic cell populations relevant to diabetes as well as establishing assays for molecular and functional characterization. The ideal candidate will have deep expertise in developmental biology, iPSC differentiation and assay development and will contribute to the advancement of the diabetes programs. The role demands hands-on experimental work with cell culture, strategic project planning and cross-functional collaboration to accelerate therapeutic development. Duties and Responsibilities • Culture and maintain iPSC lines and relevant primary cells, including preparation of media, passaging, cryopreservation, and routine quality assessments., • Conduct genetic screens on iPSCs to optimize differentiation protocols for diabetes-relevant therapeutic cell populations., • Design, execute and optimize differentiation workflows using principles of synthetic biology and stem cell biology., • Develop, establish and run molecular, phenotypic and functional assays to characterize differentiated cell populations (e.g. flow cytometry, PCR, fluorescence microscopy, ELISA and other relevant readouts)., • Perform, analyze and interpret experimental data, ensuring comprehensive documentation of methodologies and outcomes., • Troubleshoot differentiation and screening workflows to improve hit rate, throughput and robustness., • Maintain a detailed laboratory journal, summarize results, and create presentations for meetings., • Maintain accurate and complete records, ensuring compliance with documentation management systems., • Collaborate effectively across the GC Therapeutics team to achieve strategic goals. General Laboratory Roles: • Responsible for experimental design, data generation, analysis, and communication of results to supervisor, and team members., • Provide scientific and technical guidance to junior staff, collaborators, or contract research organizations (CROs) for defined projects., • Maintain organized and detailed laboratory journal, summarize results, and create presentations for internal group meetings., • Stay current on relevant scientific literature, emerging technologies and advancements in the field., • Exemplify scientific curiosity and deep expertise with relevant literature and cutting-edge technologies to advance research directions., • Work with other members of the research team and within GCTx to accomplish company goals., • Follow all safe laboratory practices and company policies. Experimental Techniques: Cellular Biology: • Perform cell engineering on iPSCs to screen factors for synthetic biology-based differentiation., • Design and execute synthetic biology-based differentiation of iPSCs., • Optimize iPSC-derived differentiation for therapeutic cell products., • Utilize techniques such as PCR, molecular cloning and plasmid isolation., • Characterize target cell types using next-generation sequencing methods (e.g. library preparation for bulk and single cell RNA-seq) and other gene expression analysis techniques. Qualifications Essential Qualifications: • Ph.D. degree in stem cell biology, cell biology, bioengineering, biochemistry, or related discipline and 5+ years of laboratory work experience in academia or industry., • Strong expertise in cell culture expertise, particularly for iPSCs and cell types relevant to diabetes., • Deep knowledge of development biology and stem cell differentiation principles as applicable to diabetes., • Proven experience in cell-based assay development and molecular biology laboratory techniques., • Strong work ethic with the ability to perform tasks independently and lead junior staff effectively., • Proficient in analysis, presentation, and documentation of scientific data and scientific reports., • Effective communicator with excellent interpersonal skills., • Strong project management and organizational skills and ability to prioritize and multitask., • Ability to work in a laboratory environment approximately 75% of the time including occasional weekend hours. Additional Preferred Qualifications: • Experience in genome editing or high throughput genetic library screening., • Skill to perform animal studies, including rodent handling, dosing., • Ability to analyze next generation sequencing or other genome-scale datasets., • Proven track record and strong publications in stem cell or developmental biology., • Knowledge of R, Python and FlowJo. Pay Range $120,000 - $145,000 (This range reflects the base salary only and does not include additional compensation such as annual bonus and equity awards, which are part of the total compensation package.) Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At GC Therapeutics, our generous competitive benefits package also include generous PTO, paid holidays, Medical, Dental, Vision, 401(k), Life and Disability Insurance and transportation subsidy. Equal Opportunity Workplace: GC Therapeutics is an equal opportunity employer. We provide equal employment opportunities to all applicants for employment and existing employees without regard to ancestry, national origin, place of birth, race, color, gender, sexual orientation, marital status, pregnancy, religion, age, disability, gender identity, results of genetic testing, service in the military or otherwise to the full extent of all federal, state and local laws. GC Therapeutics’ equal employment opportunity policy applies to all terms and conditions of recruiting, hiring, placement, training, compensation, transfer, leave of absence, employment, promotion, layoff and termination of employment.

Downstream Process Development Scientist/Engineer Department Chemistry, Manufacturing & Controls (CMC) Reports To Vice President, CMC Employment Type Contract 12 Month Location Cambridge, MA Position Overview Our client is seeking a highly motivated Downstream Process Development Scientist/Engineer to develop and optimize purification processes for therapeutic antibodies and recombinant proteins produced in mammalian cell culture. Reporting to the Head of CMC, this hands-on role will drive affinity capture resin screening, chromatography method development, and process optimization to enable robust and scalable downstream manufacturing process. Key Responsibilities • Evaluate and optimize affinity capture resins (e.g., Protein A and alternative affinity ligands) to maximize antibody recovery, yield, and resin performance., • Perform resin screening, condition optimization, and scale-down studies to establish robust and scalable purification processes., • Develop and optimize chromatography purification steps, including ion exchange (IEX), hydrophobic interaction (HIC), and mixed-mode chromatography using systems such as ÄKTA., • Design and optimize polishing steps to achieve target product purity and removal of process-related impurities (e.g., host cell proteins, aggregates, DNA)., • Analyze purification samples using common analytical techniques (e.g., HPLC/UPLC, SEC, CE-SDS, ELISA, HCP assays) and accurately interpret data to guide process development decisions., • Maintain thorough experimental documentation and data records to support process development reports, regulatory documentation, and technology transfer., • Collaborate with analytical development and external partners (e.g., CDMOs) to ensure integrated and efficient process development., • Support technology transfer of downstream purification processes to manufacturing partners and assist with process troubleshooting during scale-up. Required Qualifications • B.S., M.S., or Ph.D. in Biotechnology, Chemical Engineering, Bioengineering, or a related field with relevant industry experience (B.S. + 5 years, M.S. + 3 years, or Ph.D. + 1 year)., • Hands-on experience purifying antibodies or recombinant proteins from mammalian cell culture supernatant using chromatography systems (e.g., ÄKTA or equivalent)., • Proficiency with chromatography systems and multiple separation modes, including affinity, ion exchange (IEX), hydrophobic interaction (HIC), and size exclusion chromatography (SEC)., • Perform resin screening, condition optimization, and scale-down studies to establish robust and scalable purification processes., • Experience working with downstream unit operations, such as harvest clarification, chromatography purification, and ultrafiltration/diafiltration (UF/DF); familiarity with viral clearance strategies is a plus., • Experience working in cross-functional teams including upstream development, analytical development, quality and manufacturing., • Strong data analysis and experimental design skills; experience with Design of Experiments (DoE) is a plus., • Ability to analyze and interpret purification data to guide process optimization., • Experience supporting process scale-up and technology transfer to CDMOs or manufacturing partners. Why Join Us • Opportunity to make a direct impact in an innovative biotech and help develop a commercial product, • Highly collaborative, mission-driven culture, • Strong investor support

Title: Contract, Research Scientist, AI/ML Location: Open to Remote, within 1 hour of the Cambridge, MA office. JOB DESCRIPTION The Importance of the Role Client is expanding its capabilities in antisense oligonucleotide (ASO) therapeutics while advancing antibody and biologics discovery across multiple targets. To support this effort, we are integrating advanced machine learning (ML), artificial intelligence (AI), and data driven modeling to accelerate discovery and optimization across modalities. The Research Scientist, AI / ML Biologics will help build reproducible computational frameworks that strengthen AI/ML assisted design pipelines for ASOs and emerging biologic program. The Opportunity to Make a Difference In this role, you will develop sequence aware predictive models to prioritize oligonucleotide therapeutics based on exon skipping response and extend these approaches across diverse ASO modalities. You will also contribute to AI/ML driven antibody discovery by supporting modeling of antibody–antigen sequence, structure, and interactions, helping expand Client’s cross-modality design and decision support capabilities. Key Responsibilities • Design and implement advanced AI/ML approaches for de novo antibody discovery, including finetuning protein language models and developing generative protein design workflows., • Develop, deploy, and scale machine learning methods to support multi-objective optimization of antibodies, antigens, ADCs, and other biologic modalities., • Develop and extend sequence aware machine learning models to prioritize ASO designs by predicted exon skipping response across multiple targets and modalities, including PMO gapmers, siRNA–PMO hybrids, and conjugate designs., • Build a reproducible computational framework including data ingestion, feature engineering, model training, validation, and deployment for biologics., • Curate and harmonize internal and external literature curated datasets and define robust sequence and structure features such as thermodynamics, accessibility, sequence motifs, secondary structure, and additional context that drive model performance., • Establish benchmarks and prospective tests to assess accuracy, robustness, and scalability, and partner with experimental teams to validate predictions., • Evaluate and adopt proprietary and open source tools to enhance modeling workflows and accelerate decision support., • Maintain a clean and well documented codebase, and user guidance for cross-functional teams., • Perform additional related tasks as assigned Required Skills & Education • PhD in Computational Chemistry/Biology, Machine Learning, Biomedical/Chemical Engineering field with 3+ years of directly relevant industry experience., • A strong background in oligonucleotide chemistry, antibody design and characterization., • Proven experience in computational modeling of antibody–antigen sequence, structure, and binding interactions., • Strong expertise in developing and/or adopting probabilistic learning or deep learning models, including Recurrent Neural Networks (RNNs), Graph Neural Networks (GNNs), Transformers, Natural Language Processing models, and Generative AI., • Expert in programming and scripting languages such as Python, R, and SQL, with hands-on experience using modern deep learning frameworks such as PyTorch, Tensorflow, skikit-learn or JAX., • Experience in developing machine learning models for DNA, RNA, and proteins, including language models, structure prediction, and design., • Familiar working with large-scale computing and cloud infrastructures, database systems, and development tools in a production environment., • Familiar with data development, tools, and infrastructure: AWS, database technologies, GitHub, GitLab, and Docker containers, • Ability to effectively communicate and collaborate with a multidisciplinary team, including chemists, biologists, and data scientists to successfully complete scientific projects., • Strong team player with a commitment to continuous learning.

Our Boston based biotechnology client is seeking a highly skilled Senior or Principal Scientist to lead the development, transfer, and validation of bioassay methods supporting innovative gene therapy programs. This role is ideal for a scientifically driven professional who thrives in a dynamic, collaborative environment and is motivated by impactful work in clinical-stage development. This position requires 2-3 days per week onsite in Boston, MA. About the Role The incumbent will be responsible for establishing and managing biological potency assays used for release and stability testing. This position also oversees CRO activities for both GMP and non-GMP sample testing, ensuring high-quality execution and regulatory compliance. You will collaborate closely with cross-functional teams, contribute to analytical CMC documentation, and support regulatory submissions. This is a high-impact role with opportunities to influence analytical strategy and drive scientific excellence. Key Responsibilities • Lead development, transfer, and validation of biological assays for release and stability testing., • Manage laboratory investigations, OOS assessments, and data trending; support manufacturing investigations., • Execute development studies for process and product characterization, including comparability assessments., • Draft, review, and approve SOPs, protocols, reports, and analytical documentation for internal and external QC labs., • Support preparation of analytical CMC content for regulatory submissions, including data summaries and trend analyses., • Collaborate effectively with internal stakeholders and manage external CRO relationships. Skills and Expertise • Strong technical expertise and hands-on experience with cell-based potency assays., • Familiarity with statistical analysis tools (e.g., JMP, Prism, PLA 3.0) is an asset., • Excellent technical writing skills for analytical CMC documents, including change controls, SOPs, protocols, and reports., • Solid understanding of regulatory guidance and GMP requirements for analytical method lifecycle management., • Highly organized, detail-oriented, and capable of strategic thinking., • MS or PhD in Biological Sciences or related field, with a minimum of 10 years of biotech/pharma industry experience., • Extensive hands-on experience in analytical method development, validation, and clinical-stage sample testing., • Strong background in analytical documentation within a regulated environment., • Proficiency in cell-based assays, ddPCR, and ELISA is required., • Experience with HPLC/UPLC or CE-SDS is a plus., • Demonstrated project management, problem-solving, and organizational skills., • Experience managing CDMO/CRO partnerships is required., • Excellent written and verbal communication skills, with the ability to present findings to diverse stakeholders.

Net2Source Inc. is an award-winning total workforce solutions company recognized by Staffing Industry Analysts for our accelerated growth of 300% in the last 3 years with over 5500+ employees globally, with over 30+ locations in the US and global operations in 32 countries. We believe in providing staffing solutions to address the current talent gap – Right Talent – Right Time – Right Place – Right Price and acting as a Career Coach to our consultants. Company: One of Our Clients Job Description: Title: Bench Scientist Duration: 24+ months (Extendable) Location: Cambridge, MA 02140 Pay Rate: $30.00 - 35.00/hr on W2 ROLE SUMMARY We are seeking a highly motivated Associate Scientist to join the Molecular Assessment and Profiling group within BioMedicine Design. This role contributes to the selection of high-quality biotherapeutics candidates by generating characterization data using a suite of established biophysical and analytical methods. ROLE RESPONSIBILITIES • Learn and perform physicochemical, thermal, and colloidal stability assessment of biotherapeutic candidates using a suite of established assays., • Analyze and interpret experimental data to support selection of lead biotherapeutic molecules., • Contribute to improvement activities aimed at increasing efficiency and throughput within the group., • Accurately document experimental procedures, results, and analyses in electronic notebook BASIC QUALIFICATIONS • Bachelor’s degree (BA/BS) with at least one year relevant experience in biochemistry, or a related field, • Proficient in micropipetting and a solid foundation of general laboratory scientific practices, • Knowledgeable with various analytical techniques such as DSC, DLS, aSEC, iCE and cGE, • Strong attention to details (analytical-minded) with the ability to multitask efficiently., • Ability to learn new techniques rapidly and follow established protocols with precision., • Ability to perform tasks under close supervision with frequent review of results., • Excellent verbal and written communication skills PREFERRED QUALIFICATIONS • Experience working with automation is a plus Awards and Accolades: America's Most Honored Businesses (Top 10%) Awarded by USPAAC for the Fastest Growing Business in the US 12th Fastest Growing Staffing Company in USA by Staffing industry Analysts in the US (2020, 2019, 2020) Fastest 50 by NJ Biz (2020, 2019, 2020) INC 5000 Fastest growing for 8 consecutive years in a row (only 1.26% companies make it to this list) Top 100 by Dallas Business Journal (2020 and 2019) Proven Supplier of the Year by Workforce Logiq (2020 and 2019) 2019 Spirit of Alliance Award by Agile1 2018 Best of the Best Platinum Award by Agile1 2018 TechServe Alliance Excellence Awards Winner 2017 Best of the Best Gold Award by Agile1(Act1 Group)

About the Company A soon to launch Third Rock Ventures company is seeking an experienced Peptide Scientist to lead peptide design efforts supporting discovery-stage therapeutic programs. This role will focus on peptide SAR, data interpretation, and lead optimization, working closely with project leadership and cross-functional teams. Responsibilities • Lead and design strategies for peptide therapeutics to support early discovery programs, • Drive structure–activity relationship (SAR) efforts and guide molecule optimization, • Manage and oversee work conducted at external CRO partners, including peptide synthesis, analytics, and related studies, • Review and interpret experimental data to inform molecule design and program strategy, • Present program updates and recommendations to project teams, • Partner closely with project leads and cross-functional teams (biology, pharmacology, DMPK, CMC) to advance programs, • Help define external study plans, timelines, and priorities to support program milestones Qualifications • PhD in chemistry, chemical biology, peptide science, or related field, • Significant experience in therapeutic peptide discovery, • Expertise in metabolic or endocrine indications, • Demonstrated ability to guide molecule design and SAR strategy, • Track record of contributing to advancement of discovery programs, • Experience managing external CRO collaborations, • Strong communication skills and ability to present scientific strategy to multidisciplinary teams Required Skills • Experience in therapeutic peptide discovery and optimization, • Ability to guide peptide design and SAR strategy, • Strong communication skills, • Experience managing external CRO collaborations, • Ability to present scientific strategy to multidisciplinary teams Location • With offices in Boston, San Francisco and Shanghai, the ability to work from one of these locations, but we are open to remote employment for exceptional individuals able to work collaboratively and effectively Equal Opportunity Statement We are committed to diversity and inclusivity.

We're seeking a senior predictive modeler to join our Property & Casualty Actuarial team to develop scalable analytics and predictive modeling solutions that drive business decisions. In this role, you'll explore and synthesize large, complex datasets; frame hypotheses and research approaches; and build, deploy, and monitor statistical and machine learning models (GLM/GBM preferred) that support pricing, reserving, and other actuarial objectives. You'll combine strong business acumen with advanced quantitative methods and modern software engineering practices-especially Python-based development, testing, and source control-to deliver reliable, production-ready solutions and actionable insights Position Compensation Range: $88,000.00 - $145,000.00 Pay Rate Type: Salary Compensation may vary based on the job level and your geographic work location. Relocation support is offered for eligible candidates. Responsibilities: • Uses actuarial and technical knowledge to manage complex projects as assigned in such areas as product development and pricing., • Creates business application and modeling framework, for new datasets, and discovers insights and relationships from large/complex datasets through investigative research using advanced mathematical and/or statistical techniques., • Explores data using a variety of advanced statistical techniques to proactively identify relationships, create insights and answer business questions or guide future model development., • Builds the hypothesis, identify research data attributes and determine best approach to address business issues., • Combines business/actuarial acumen with mathematical capabilities to build complex predictive models to support business objectives., • Builds complex programs for running mathematical or statistical tests on data and for understanding complex relationships across attributes., • Incorporates findings and provides industry and competitor insights as part of model development and enhancement., • Researches and maintains awareness of industry best practices and business strategies., • Brings new and innovative ideas and approaches to develop business solutions., • Maintains standard documentation on assigned projects/tasks., • Consults with other departments by answering inquiries and providing explanations of a business/actuarial nature., • May be requested to complete other assignments or participate in projects based upon skills, achievements, or experience. Requirements: • Deployed and monitored predictive models in production (preference for GLM/GBM), partnering with actuarial and engineering teams to ensure scalable, governed, and repeatable pricing/reserving workflows., • Advanced programming proficiency with a strong preference for Python; build robust, tested analytics pipelines and model code for end-to-end actuarial use cases (data prep, modeling, validation, and automation)., • Preferred experience in designing and deploying AI/ML solutions to solve business problems, demonstrating a pragmatic approach to solution-selection and an understanding of when a non-AI approach is optimal., • Demonstrated experience providing customer-driven solutions, support, or service., • Demonstrated experience, communicating complex actuarial analysis to business partners., • Advanced knowledge of and demonstrated experience using actuarial software with database tools and statistical tools., • Demonstrated experience with programming languages., • Demonstrated effective communication and problem-solving skills., • In pursuit of Associate or Fellow in Casualty Actuary Society. Offer to selected candidate will be made contingent on the results of applicable background checks * Offer to selected candidate is contingent on signing a non-disclosure agreement for proprietary information, trade secrets, and inventions * Sponsorship will not be considered for this position unless specified in the posting Licenses: *Not Applicable. Travel Requirements *Up to 10%. Physical Requirements *Work that primarily involves sitting/standing. Working Conditions *Not Applicable. We provide benefits that support your physical, emotional, and financial wellbeing. You will have access to comprehensive medical, dental, vision and wellbeing benefits that enable you to take care of your health. We also offer a competitive 401(k) contribution, a pension plan, an annual incentive, 9 paid holidays and a paid time off program (23 days accrued annually for full-time employees). In addition, our student loan repayment program and paid-family leave are available to support our employees and their families. Interns and contingent workers are not eligible for American Family Insurance Group benefits. We are an equal opportunity employer. It is our policy to comply with all applicable federal, state and local laws pertaining to non-discrimination, non-harassment and equal opportunity. We also consider qualified applicants with criminal histories, consistent with applicable federal, state and local law. American Family Insurance is committed to the full inclusion of all qualified individuals. If a reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please email ___ to request a reasonable accommodation. #LI-TB1

Immediate need for a talented Scientist I. This is a 06+ Months Contract opportunity with long-term potential and is located in Waltham, MA (Onsite). Please review the job description below and contact me ASAP if you are interested. Job ID:26-08585 Pay Range: $50 - $56/hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location). Key Responsibilities: • The successful candidate will participate in the development and validation of analytical methods involving cell-based assays, PCR-based assays, and other analytical techniques routinely used to support gene therapy development., • A strong bioassay background is desired, with a minimum of 2-4 years’ experience in an industry setting performing cell-based assays., • Molecular biology experience is also a benefit., • This individual will conduct pre-clinical and clinical lot release and stability testing of viral and non-viral gene therapies., • This role operates within a cGMP environment and requires excellent verbal and written communication skills, strong attention to detail, and the ability to collaborate effectively with cross-functional departments., • We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives., • We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started? Key Requirements and Technology Experience: • Must Have Skills- Hands-on cell-based assay experience Molecular biology expertise, including PCR Assay development experience, • Nice-to-Have Skills ELISA experience (Enzyme-Linked Immunosorbent Assay) Electronic Lab Notebook (ELN) familiarity Experience working in GxP environments Tools / Platforms ELN ELISA JMP or GraphPad Prism, • Education & Experience Bachelor’s degree + 2–4 years of relevant industry experience Master’s degree + ~2 years of relevant experience PhD not required, but candidates with a PhD will be considered, • Works well independently while possessing strong leadership & communication skills and a demonstrated history of building collaborative, lasting relationships that deliver business results, • Ability to work well in a fast-paced environment and handle multiple priorities successfully, • Ability to work closely with cross functional and other internal teams, • High level of energy, drive, enthusiasm, and commitment with a strong bias for action and prioritization, • Outstanding verbal and written communication skills, as well as demonstrated ability to work confidently and respectfully at all levels of an organization, both internally and externally, • Someone who is highly creative with the ability to think out of the box, • Comfortable working with numbers, metrics & spreadsheets, • Able to influence key partners with ideas that build value. Our client is a leading Healthcare Industry and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration. Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. By applying to our jobs you agree to receive calls, AI-generated calls, text messages, or emails from Pyramid Consulting, Inc. and its affiliates, and contracted partners. Frequency varies for text messages. Message and data rates may apply. Carriers are not liable for delayed or undelivered messages. You can reply STOP to cancel and HELP for help. You can access our privacy policy ___.

< Overview: We are seeking a Principal Scientist to join the Protein Sciences team to drive cell line and upstream process development for the production of monoclonal antibodies and antibody-oligo conjugates. The candidate will work across functions to advance molecules from discovery through to clinical readiness and will oversee all activities at selected CDMOs. The candidate will bring deep expertise in cell line development and act as the liaison between Research and CMC to ensure smooth transition from discovery to manufacturing. This position is onsite and will be located at our Kendall Square offices in Cambridge, MA. Responsibilities: • Lead the development, selection, and characterization of stable, high-titer cell lines for the production of monoclonal antibodies and antibody-oligo conjugates., • Evaluate, select, and manage CDMOs to execute regulatory-compliant cell line development activities including clonality documentation and cell bank generation., • Supervise all cell line development processes including construct design, generation of stable pools, clone screening, characterization, and cell line stability., • Analyze protocols, development reports, and other data packages generated by CDMOs., • Ensure activities completed at CDMOs align with project goals, timelines, and quality standards., • Support regulatory filings by authoring and reviewing relevant sections related to cell line development., • Work cross-functionally with internal teams including research, CMC, regulatory, and clinical to ensure seamless transfer of knowledge., • Contribute to a cross-functional team of biologists, chemists, and pharmacologists to drive the strategic direction of research programs across multiple therapeutic modalities. Qualifications: • Ph.D. in Chemical Engineering, Biochemical Engineering, Pharmaceutical Sciences, Biology, or related field with 6-10 years of relevant experience., • Deep expertise in cell line development for production of therapeutic proteins including monoclonal antibodies, antibody-drug conjugates, or antibody-oligo conjugates., • Strong technical background in all aspects of cell line development including molecular biology, vector design, single cell cloning technologies, cell line characterization, and industry-leading antibody production platforms., • Additional expertise in antibody design and protein engineering is a plus., • Proven track record of managing CDMOs and delivering on biologics development programs., • Experience working across multiple projects simultaneously in a fast-paced, cross-functional environment., • Excellent written/oral communication, organizational, and interpersonal skills are required to work effectively across teams. #LI-KB1 #LI-Onsite U.S. Pay Range $147,200.00 - $220,800.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< The Sr. Scientist in Clinical Pharmacology position will support a rapidly expanding clinical portfolio of promising RNAi therapeutics. The candidate in this position should be well versed in PK and PD with strong ability to critically evaluate and interpret data, conduct noncompartmental analysis, and PKPD modeling. In this role, the candidate is expected to have a strong critical thinking ability with excellent oral and written communication skills. Summary of Key Responsibilities • Represent Clinical Pharmacology and provide PKPD support and guidance to early and clinical stage project teams., • Lead the analysis, interpretation, integration and reporting of clinical pharmacokinetic & pharmacodynamic data, • Conduct PK/PD analyses and data visualization to guide development decisions on project teams; ability to use model-based approaches to aid decision making, • Provide PKPD input for regulatory submissions such as briefing documents, IND, CTA and NDA., • Contribute to protocol preparation, study execution, data review/analysis, study reports and regulatory document preparation, • Closely partner with Research, Bioanalytical, Clinical development, Regulatory, Project Management, biostatistics and other R&D functions., • Ph.D. in Pharmacokinetics, Pharmacology, Pharmaceutics or other relevant field with 2-3 years' experience in pharmaceutical industry, or M.D or Pharm.D. with equivalent experience. Level and responsibilities will depend on the individual's experience and interpersonal skills., • Strong knowledge of clinical pharmacology principles in drug development including PKPD, modeling and simulation, ADME concepts, and clinical pharmacology., • Hand-on experience in using R and other data visualization techniques for representation of PKPD data., • Proficient in using Phoenix WinNonlin, Phoenix NLME, R, NONMEM, or other pharmacokinetic, modeling software. Training in application of pharmacometric principles or software would be a plus. $140,300.00 - $189,700.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Job Description Summary Internal Title: Senior Principal Scientist or Associate Director #LI-Hybrid Location: Cambridge, MA USA In this key role you will provide pathology subject matter expertise across drug discovery and development programs throughout the nonclinical and clinical development lifecycle, and/or contributes to department aligned technology development. You will also apply deep scientific judgment to assess the impact, limitations, and value of pathology data to advance projects, inform human risk assessment, and support Novartis portfolio strategy. You will have the opportunity to collaborate broadly across project teams, therapeutic areas, modalities, and external partners while maintaining compliance with Novartis policies, SOPs, GxP, One Quality, and health and safety requirements. Job Description Key Responsibilities: • Generate, evaluate, and interpret GLP and non-GLP pathology data for assigned studies, including determination of adversity where appropriate., • Conduct and/or support postmortem phases of toxicology studies, including pathology peer and scientific review., • Contribute to integrated nonclinical data analyses, interpretation, human risk assessment, and high quality reporting., • Support regulatory submissions through preparation and review of pathology related documentation., • Serve as a pathology contributor or early project team representative for preclinical safety., • Participate in nonclinical study design, protocol writing, and review., • Monitor and review pathology procedures and data generated by CROs and external partners., • Provide scientific and technical interpretation using expertise in clinical pathology, histopathology, histochemistry, morphology, image analysis, transcriptomics, electron microscopy, and related techniques., • Identify and contribute to novel projects or emerging scientific/technical areas aligned with departmental strategy., • Maintain current knowledge of scientific advances, technologies, and methodologies., • Collaborate across therapeutic areas and modalities; identify key connection points to enable project progression. Essential Requirements: • Education: DVM (or equivalent, e.g., BVSc), • Graduate training in pathology, • Preferred candidate will also have a PhD in a relevant biological or toxicologic field and 2 plus years of experience in toxicologic pathology; 5 plus years to be considered at the Associate Director level, • Pathology board certification (e.g., DACVP, ECVP, FRCPath) To be considered at the Associate Director level you will also have: • Demonstrated team leadership, • Ability to supervise direct and develop others, • Experience leading programs, platforms, or initiatives This is a dual posting. The final level & title of the offer role would be determined by the hiring team based on the skills, experience & capabilities required to perform the role at the level the role has been offered. The salary for this position is expected to range between: Senior Principal Scientist I: $176,400 and $327,600 per year. Associate Director: $185,500 and $344,500 per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click ___. EEO Statement: The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility and reasonable accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Salary Range $176,400.00 - $327,600.00 Skills Desired Analytical Thinking, Bioinformatics, Clinical Data Management, Collaboration, Communication Skills, Critical Thinking, Data Analysis, Detail-Oriented, Drug Discovery, Ethics, Laboratory, Lifesciences, Management, Medical Research, Organization, Problem Solving Skills, Regulatory Compliance, Reports Writing, Team Management, Technical Skills, Time Management Skills, Toxicology, Training, Waterfall Model

Ardelyx is a publicly traded commercial biopharmaceutical company founded with a mission to discover, develop and commercialize innovative first-in-class medicines that meet significant unmet medical needs. Ardelyx has two commercial products approved in the United States, IBSRELA (tenapanor) and XPHOZAH (tenapanor). Ardelyx has agreements for the development and commercialization of tenapanor outside of the U.S. Kyowa Kirin commercializes PHOZEVEL (tenapanor) for hyperphosphatemia in Japan. A New Drug Application for tenapanor for hyperphosphatemia has been approved in China with Fosun Pharma. Knight Therapeutics commercializes IBSRELA in Canada.Position Summary:The Associate Director, Stability is a self-motivated individual who works as a member of an integrated team at Ardelyx contracting, designing, managing, and evaluating stability studies at contractors for both drug substance and drug product. This individual should have the breadth of experience required to manage stability studies in early stage as well as in commercial stage. This individual should have a good knowledge of ICH and cGMP guidelines and the ability to contribute to regulatory filings as needed for stability.Please note: this position is hybrid-based out of our Waltham, MA or Newark, CA office and requires a presence on-site 2-3 days per week.Responsibilities: • Develop and implement the strategic direction of stability programs aligned with corporate goals and product life-cycle objectives, • Oversee the design, execution, and management of stability studies (development, registration, and commercial), • Work cross functionally with CMC, supply chain, quality, regulatory, clinical and related teams to achieve stability objectives, • Contract with and manage manufacturing and analytical contractors conducting stability studies including supporting finance in forecasting and expense tracking, • Coordinate and facilitate the movement of material to stability contractors from manufacturing sites as needed, • Initiate and drive stability protocol generation and other quality documents in support of stability studies, • Compile stability study results, perform trend and statistical analyses, and prepare reports to support retest/shelf-life date extensions and storage condition recommendations, • Partner with quality during stability quality events (QEs) or investigations and implementation of CAPAs at contractors, • Author CMC stability documentation for IND, NDA and IMPD filings, covering all phases of clinical development and commercial activities, • Represent the stability function and present work at intra/inter departmental meetingsQualifications:, • B.S. degree in a scientific field, such as chemistry or biology, with 10+ years' experience working in the pharmaceutical industry or equivalent experience, • Excellent working knowledge of small molecule analytical chemistry with prior experience as an analytical scientist desirable, • Flexible and adaptive team player with excellent verbal and written communication skills, • Exceptional organizational skills and meticulous attention to detail, • Extensive experience with small molecule drug product and drug substance stability programs, • Experience managing contractor stability activities, • Extensive experience with ICH and FDA guidelines, • Experience in authoring regulatory submissions (IND, NDA, MAA) and associated reports, • Ability to travel up to 5% domestically or internationallyThe anticipated annualized base pay range for this full-time position is $169,000-$207,000. Ardelyx utilizes industry data to ensure that our compensation is competitive and aligned with our industry peers. Actual base pay will be determined based on a variety of factors, including years of relevant experience, training, qualifications, and internal equity. The compensation package may also include an annual bonus target and equity awards, subject to eligibility and other requirements.Ardelyx also offers a robust benefits package to employees, including a 401(k) plan with generous employer match, 12 weeks of paid parental leave, up to 12 weeks of living organ and bone marrow leave, equity incentive plans, health plans (medical, prescription drug, dental, and vision),life insurance and disability, flexible time off, annual Winter Holiday shut down, and at least 11 paid holidays.Ardelyx is an equal opportunity employer.

Job Description Summary The Principal Scientist, ADPKD Biology Lead is a senior, lab-embedded scientific leader responsible for shaping and executing ADPKD discovery biology strategy across a portfolio of preclinical programs. The role will translate insights from human genetics and disease biology into differentiated target hypotheses, lead target triage and validation in advanced human-relevant model systems, including 3D platforms, and deliver decision-grade biology packages to enable robust, biology-driven portfolio go/no-go decisions and progression to preclinical proof-of-concept. Job Description Internal Position Title: Principal Scientist I/II Position Location: onsite, Cambridge, MA #LI-onsite Position Summary: We are expanding our efforts in autosomal dominant polycystic kidney disease (ADPKD) to delineate key drivers of renal cyst pathophysiology and develop transformative therapies beyond the current standard of care. The Principal Scientist, ADPKD Biology Lead is a senior, lab-embedded scientific leader responsible for shaping and executing ADPKD discovery biology strategy across a portfolio of preclinical programs. The role will translate insights from human genetics and disease biology into differentiated target hypotheses, lead target triage and validation in advanced human-relevant model systems, including 3D platforms, and deliver decision-grade biology packages to enable robust, biology-driven portfolio go/no-go decisions and progression to preclinical proof-of-concept. Key Responsibilities: * Lead a portfolio of renal discovery programs from target hypothesis through preclinical proof-of-concept (PoC) and transition toward clinical candidate selection. * Serve as the ADPKD disease biology lead, defining and evolving discovery biology strategy across the portfolio, including target prioritization and biology-driven go/no-go recommendations. * Lead the triage and validation of novel biological insights emerging from functional genomics, phenotypic screening, and pharmacologic or genetic perturbation studies. * Design fit-for-purpose experimental strategies to establish mechanism of action, pathway engagement, and efficacy-relevant biology in ADPKD. * Maintain a strong understanding of the external scientific and competitive landscape in ADPKD and broader chronic kidney disease; identify emerging targets, modalities, and partnership opportunities to sustain innovation. Essential requirements: * PhD in nephrology, physiology, pharmacology, molecular biology, cell biology, biochemistry, or a related discipline. * Significant postdoctoral and/or industry experience in kidney disease research, typically 8-10+ years, with meaningful drug discovery experience in a pharmaceutical or biotechnology setting. * Deep expertise in ADPKD biology and/or strong experience in the pathophysiology of renal cystogenesis, including areas such as cilia biology, polycystin trafficking, epithelial biology, inflammation, or metabolism. * Demonstrated experience across multiple stages of drug discovery, including target identification and validation, assay strategy, and mechanistic pharmacology. * Strong hands-on understanding of state-of-the-art in vitro methods, including molecular biology, biochemistry, and cellular analytics, as well as translatable cellular disease models in both 2D and 3D systems (advanced kidney organoids). * Proven ability to lead, mentor and develop a high-performing team of scientists, and to coach research associates and junior scientists. * Excellent written and verbal communication skills in English, including the ability to present complex datasets clearly and concisely to diverse audiences Desirable Qualifications: * Expertise with complex renal cell platforms (3D human cyst models/organoids and engineered renal epithelial platforms; primary renal epithelial and stromal co-culture systems (2D and 3D) relevant to cystogenesis). * Proficiency in leveraging large-scale datasets (genetics, next-generation sequencing (NGS), single-cell omics) to inform biology, target selection, and stratification. The salary for this position is expected to range between $108,500 and $201,500 per year for Principal Scientist I, and $126,000 and $234,000 per year for Principal Scientist II. The final salary offered is determined based on factors like, but not limited to, relevant skills andexperience, and upon joining Novartis will be reviewed periodically. Novartis may change the publishedsalary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of therole, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life anddisability benefits, a 401(k) with company contribution and match, and a variety of other benefits. Inaddition, employees are eligible for a generous time off package including vacation, personal days,holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click ___. EEO Statement: The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility and reasonable accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Salary Range $108,500.00 - $201,500.00 Skills Desired Analytical Skill, Analytical Skill, Analytical Thinking, Chemical Biology, Chemistry, Clinical Trials, Collaboration, Communication Skills, Curious Mindset, Data, Data Analysis, Design Of Experiments, Detail-Oriented, Drug Development, Drug Discovery, Ethics, Gene Therapy, Immunology, Inventory Management, Laboratory, Lifesciences, Machine Learning (ML), Management, Medical Research, Molecular Biology {+ 10 more}

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Vice President , Global Clinical Lead - Solid Tumor in our Cambridge office. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Here, you will be a vital contributor to our inspiring, bold mission. OBJECTIVES: Responsible for leading as the Global Clinical Lead a large solid tumor oncology franchise that encompass multiple late stage and early phase programs . Ensures ongoing review and agreement of the Therapy Area Strategy and associated documents formulated by the OTAU leader prior to their review and approval by appropriate governance committees. Oversees the development and execution of the Integrated Disease Area Strategy (IDAS) and overall Integrated Global Development Plan (IGDP). Responsible for review of synopses, other relevant clinical study documents and critical Study Results. Provide leadership and oversight of specific OTAU related programs and if applicable other indication specific clinical leads. Responsible for providing guidance to TA leaders on regional specificities within Therapeutic Area. ACCOUNTABILITIES: - Clinical Development team participation and leadership - Accountable to Oncology Clinical Science Head to provide strategic clinical input on assigned clinical studies. - Consistent with the Takeda R&D Oncology Therapeutic Area Unit strategy, goals and objectives, this leader will partner with the other key functions and leaders and members of Oncology Precision and Translational Medicine, Oncology Portfolio Strategy Group, Global Regulatory Affairs, Quantitative and Clinical Pharmacology, other R&D Functional Line Oncology Therapeutic Area Leads, Global Product Launch Strategy Oncology Franchise Leads, Regional Oncology Franchise Leads, Oncology Drug Development Unit (DDU) and other Oncology extended leadership, to drive the alignment on global clinical research and development strategy as related to internal and external pipeline and non-pipeline initiatives for the Takeda R&D Oncology Community across all regions - Part of the Oncology Clinical Sciences Leadership Team providing key input in strategic planning and connectivity for the overall Oncology Clinical Sciences group - Leads the Global Development Team (US, EU, and others) managing both the US/EU Development Team and the Japan/ China Development team for assigned compounds. In some cases may lead the US/EU Development Team but more likely will oversee the study physician and/or clinical scientist leads responsible for leading the team. Emphasis will be on insuring that the development teams are proactively identifying contingencies, potential risks and strategies to address future obstacles. - Directs Development Team strategy and deliverables overseeing the Development Strategy, Clinical Development Plan and Clinical Protocols. Recommends scope, complexity and size, which influence the budget of all aspects of a program. Provides continual critical evaluation of the development strategy to maintain a state-of-the-art development plan that is competitive and consistent with the latest regulatory requirements, proactive identification of challenges, and development of contingency plans to meet them. - Responsible for high impact global decisions: interpreting data from ongoing internal and external studies, assessing the medical and scientific implications and making recommendations that impact regional and global development such as “go/no go” decisions or modification of development plans or study designs that may have a significant impact on timelines or product labeling. Plans clinical development strategies in context of medical/clinical significance considering how a given product will fit in with current treatments, standard of care, and unmet medical need. - Accountable for ensuring regional strategies and trade-offs in regional requirements are well articulated in the global strategy documentation and that stakeholders are appropriately briefed. - Providing strategic input into global development strategies and plans for all compounds in OTAU. - Providing clinical and strategic support to evaluation of external compounds (alliances and in-licensing opportunities) - Primary interface with Medical Affairs team for strategy and to support of product commercial efforts - Contributing to the creation and maintenance of regional KOL network - Providing recommendations for GDT leader nominations and reviewers of external compounds as part of business development efforts - Liaison with Clinical Operations and Project Management for co-ordination of logistics study planning and implementation - Synopsis / Protocol Development, Study Execution, & Study Interpretation - Consistent with membership of the Clinical Review Board Committee, responsible for critical review of synopses, protocols, IBs and relevant clinical documents relating to studies in assigned compounds. - Trial Medical Monitoring - Reviews and assesses overall safety information in conjunction with Pharmacovigilance and Medical Monitor of record for assigned compounds. - External Interactions - Oversees and leads all clinical science activities involved in interactions with FDA, other regulatory agencies and key opinion leaders relevant to assigned compounds. - Responsible for evaluation of external interactions in the context of overall development strategies using complex problem solving in the region but in context of a global environment. - Proactive identification of challenges and development of contingency plans as appropriate. - Due Diligence, Business Development and Alliance Projects - Responsible for evaluation of potential business development opportunities in the region but with the context of a global environment. - Conducts due diligence evaluations, of clinical development plans for potential alliances and or in-licensing opportunities. - Serves as clinical contact point for ongoing alliance projects and interface with partner to achieve Takeda’s strategic goals while striving to maintain good working relationship between Takeda and partner. - Assigns and manages clinical science staff who are involved in many of these activities. - Leadership, Task Force Participation, Upper Management Accountability - Interacts directly with research division based on pertinent clinical and development expertise and in all aspects relating to assigned compound in regional area. Leads TGRD internal teams and global cross-functional teams. Works with functional leadership to prioritize projects within the therapeutic area. - Hires, manages, mentors, motivates, empowers, develops and retains staff to support assigned activities. Conducts performance reviews and drive goal setting and development planning. EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS: Experience - MD or combined MD/PhD or internationally recognized equivalent with minimum 15 years pharmaceutical research experience, including minimum 10 years late phase clinical development experience with a focus on medical oncology - Clinical Training and Clinical Experience in Hematology/Oncology and/or Medical Oncology especially in solid tumor malignancies - Strong depth of scientific and clinical understanding and experience in cancer biology especially in immune based therapies. - Experience in conducting and/ or leading multiple clinical trials involving immune based therapies - Proven experience in successfully leading and supervising direct reports including several physicians, physician scientists, scientists within a clinical development team in a global matrix environment. - Demonstrated ability to foster a high-performance culture and build organizational capabilities. - Strong leadership commitment to diversity, equity and inclusion, with experience in creating an inclusive and collaborative team environment that leverages diverse perspectives. - Previous experience in successfully leading several clinical development team/matrix team with responsibility for Global studies in multiple regions. Clinical Development experience beyond US/EU - Solid and Multiple experience in preparing and interacting with multiple regulatory agencies including FDA, EMA, and others - Multiple NDA/MAA submission experience - Proven ability to lead and manage highly trained medical, scientific, and technical professionals. - Superior communication, strategic, interpersonal and negotiating skills - Enterprise level leadership with the ability to inspire, motivate and drive results - Excellent communication both verbally and in writing and influencing skills, with the ability to engage, inspire, and influence stakeholders at all levels, including executive management and external partners. - Ability to proactively predict issues and solve problems - Ability to drive decision-making within a multi-disciplinary, multi-regional, matrix teams - Diplomacy and positive influencing abilities across multinational business cultures TRAVEL REQUIREMENTS: - Willingness to travel to various meetings or client sites, including overnight trips. Several international travels may be required. - Requires approximately 25-35 % travel. Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy. #LI-JT1 Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $307,300.00 - $482,900.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

< Overview The Research Department at Alnylam is seeking a highly motivated and creative scientific leader to join our Next Wave, Target Discovery and Validation team. Our mission is to discover novel genetically informed targets and experimentally validate them to build a strong foundation for future RNAi therapeutics. By working closely with the Alnylam Human Genetics team, we integrate large-scale human genetic insights with deep biological expertise to generate high-confidence therapeutic targets. This role offers a unique opportunity to help shape the strategic direction of the next generation of RNAi medicines. You will collaborate cross-functionally with colleagues in genetics, translational science, RNAi platform, delivery sciences, clinical development, and commercial functions. This position also includes responsibility for managing and mentoring scientists and associate scientists. This position is onsite and will be primarily located in Cambridge, MA. Key Responsibilities • Identify areas of unmet medical need and initiate target identification workflows in collaboration with statistical geneticists and translational science teams, • Design and execute in vitro and in vivo studies to validate candidate targets and elucidate underlying molecular and physiological mechanisms of action, • Analyze, interpret, and present scientific data at internal meetings and contribute to strategic planning discussions, • Lead collaborations with external partners, CROs, and academic institutions, including project strategy, experimental design, planning, data interpretation, and decision-making, • Communicate effectively and collaborate with key stakeholders across the organization, • Manage and mentor junior scientists and associate scientist Qualifications • PhD in biology or a related biomedical field with >10 years of postdoctoral experience and a strong record of high-quality publications, • Successful candidates must demonstrate strong scientific curiosity, flexible mindset, and passion for learning and applying knowledge across diverse therapeutic areas, biological pathways, tissues/cell types, and therapeutic modalities, • Proven expertise in developing and characterizing in vitro, ex vivo, and in vivo models, with a deep understanding of disease biology, pathogenesis, and mechanisms of action, • Experience in interpreting human genetics analyses (e.g., GWAS, PheWAS, Mendelian randomization, eQTL/pQTL/sQTL) to inform therapeutic target discovery is required, • Experience designing and executing experiments to validate genetic variants and their biological consequences is a strong plus, • Thrives in a fast-paced team environment with excellent written and verbal communication skills #LI-JR1 U.S. Pay Range $147,200.00 - $220,800.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Job Description Summary #LI_Hybrid Location: Cambridge or San Diego (USA) We are seeking an enthusiastic and motivated PK Sciences project team representative to develop and implement translational or clinical pharmacology strategies to support the pursuit of transformative new medicines through late clinical development. Our unique organizational structure enables colleagues to work seamlessly in the translational and/or clinical space, offering opportunities for development and bench-to-bedside-to-bench translation. Experience in late discovery into clinical development is preferred. The scope of the role potentially includes small molecules, biologics/therapeutic proteins, antibody drug-conjugates, radioligand therapies and/or cell therapies across major therapeutic areas in Novartis, including oncology, immunology, cardiovascular renal metabolism, neuroscience, and global health. This position drives close interdisciplinary collaboration among the PK Science disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), and Operations through PK science sub-teams to achieve a holistic and integrative perspective of the ADME/clinical pharmacology properties of candidates and drugs. Collaborates effectively with broader, crossdisciplinary project teams to ensure PKS strategies are well integrated into project plans and scientific discussions. Job Description Key responsibilities: • Represent the PK Sciences function in project teams, interactions with stakeholders within the organization and interactions with regulatory agencies, as appropriate, • Proactively contributes to developing drug candidates across Research Development and Commercial continuum, providing expert pharmacokinetic / drug metabolism and clinical pharmacology input, • Work with teams to elucidate the understanding of PK/PD relationships and develop dosing strategies and predictions, • Develop and execute clinical pharmacology strategies, including input into nonclinical and clinical study design, and analyzing PK and PK/PD data, to support compound development from discovery through late development, • Provide PK, dosage, and PK/PD components of study protocols, reports, project summaries and development plans, and author pharmacokinetic/clinical pharmacology/biopharmaceutics sections of IND/IMPDs and NDA/BLAs as well as prepare appropriate responses to Health Authority questions, • Drive close interdisciplinary collaboration among the PK Science disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), through PK science sub-teams., • Works in close collaboration with clinicians and clinical development colleagues to integrate PKS insights into study design, data interpretation, and project decisionmaking, • Use of Artificial intelligence (AI) / Machine Learning (ML) approaches to enable model guided molecular design, preclinical and clinical data automation, authoring regulatory documents, and the use of predictive models This role reports to Therapeutic Area group in PK Sciences within Translational Medicine (TM) in Biomedical Research. PKS is a global organization situated within Translational Medicine (TM), the clinical research arm of Biomedical Research within Novartis. PK Sciences plays a pivotal role in bringing innovative medicines to patients, by building on research advances to develop new therapies, bridging drug discovery and clinical application. PK Science is an enterprise-wide organization, working across both Biomedical Research and the Development organizations to advance the scientific knowledge of pharmacokinetics, metabolism and clinical pharmacology. Essential requirements: • Ph.D. / Pharm.D. with relevant experience in clinical pharmacology, drug metabolism and pharmacokinetics or a related background., • A minimum of 0-2 years of experience in drug discovery and/or development in a relevant environment (academia, CRO, biotech or Pharma). 2+ years of experience preferably in a lead role overseeing ADME/DMPK project strategy, either in discovery or clinical development to be considered for Principal Scientist II, • Extensive and in-depth knowledge of pharmacokinetics including, drug metabolism and PK/PD evaluation, experience in working in project teams (preferably global) as well as sound awareness of recent developments in drug development and regulatory sciences., • Exposure to working in a cross-functional, matrixed, project-team environment., • Strong oral and written communication skills. Desirable Requirements: • Hands-on project experience with Artificial intelligence (AI) / Machine Learning (ML) approaches is a plus Leadership / Novartis Behaviors in Action • Delivers results through disciplined execution, continuous improvement, and a strong focus on value and outcomes., • Demonstrates an enterprise mindset and strong ownership by prioritizing resources and decisions for maximum Novartis and patient impact., • Role models Novartis leadership behaviors through visible actions, continuous self reflection, and openness to feedback, • Builds trust through transparent communication, clear accountability, and consistent delivery against commitments. AI fluency: • Brings strong AI and digital fluency, using enterprise tools to enhance insight generation, decision making, and team productivity. This is a dual posting. The final level & title of the offer role would be determined by the hiring team based on the skills, experience & capabilities required to perform the role at the level the role has been offered. The salary for this position is expected to range between: Principal Scientist I: $108,500 and $201,500 per year. Principal Scientist II: $119,700 and $222,300 per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click here. EEO Statement: The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility and reasonable accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Salary Range $108,500.00 - $201,500.00 Skills Desired Chemistry, Clinical Pharmacology, Clinical Research, Drug Discovery, Initiative, Medical Research, Patient Care, Physiology, Quality Control, R&D (Research And Development), Simulation Software, Translational Medicine

< Talent Acquisition Partner: Jeannine Ripley Hiring Manager: Elena Stamenova Overview Our RNAi Lead Development team is seeking a motivated Associate Scientist II to join our interdisciplinary team, whose mission is pre-clinical evaluation of siRNA-based therapeutics and advancement of our clinical stage pipeline The successful candidate will support RNA sequencing core function and expand next generation sequencing based assay pipeline. This position is onsite and will be primarily located in Cambridge, MA. Key Responsibilities • Support various transcriptomics studies via bulk, small RNA , long read , single cell , spatial and other platforms., • Execute day to day operations for RNASeq sample preparation, including: RNA isolation, library preparation, QC and sequencing., • Responsible for the operation and maintenance of NGS equipment and supplies., • Maintain samples and oversee logistics of data generation and collection., • Prepare protocol and data reports., • Troubleshoot technical problems and participate in the continuing development and optimization of existing and new protocols and technologies., • Train and assist additional personnel as needed., • Adapt to the changing platform needs, in workflow, projects and other tasks as required by the platform. Qualifications • BS in a biological science., • At least 1+ years of hands-on laboratory experience in NGS and/or molecular biology are required., • Experience with laboratory automation including liquid handling systems such as Beckman Coulter or other systems desired. U.S. Pay Range $67,600.00 - $101,400.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview We are seeking an accomplished and motivated Principal Scientist to lead innovation in advanced in vitro modeling to enable RNAi discovery and development. In this role, you will be responsible for designing, validating, and implementing physiologically relevant model systems-such as iPSC-derived models, organoids, and microphysiological systems (MPS)-to enhance biological predictivity, deepen mechanistic understanding, and increase translational confidence across multiple therapeutic areas. The ideal candidate will have a strong background in cellular and molecular biology, experience with complex in vitro model development, and a passion for leveraging advanced systems to drive impactful RNAi therapeutics. This position is onsite and will be primarily located in Cambridge, MA. Key Responsibilities • Lead and mentor the Advanced In Vitro Delivery group, fostering scientific excellence and ensuring the team remains at the forefront of emerging technologies and methodologies., • Shape scientific strategy by staying current with advances in RNAi therapeutics and contributing to the strategic direction of discovery and platform development efforts., • Collaborate cross-functionally with internal teams and CRO partners to develop, validate, and implement advanced in vitro systems-including 2D, 3D, organoid, and organ-on-a-chip models-that are predictive of in vivo siRNA uptake and biological activity., • Drive experimental execution, including design, implementation, and troubleshooting of complex in vitro studies to evaluate siRNA delivery and mechanism of action., • Provide technical leadership in the development and deployment of next-generation in vitro modeling technologies across multiple tissue types., • Adapt and miniaturize advanced cell culture systems for automated, high-throughput screening applications., • Perform and oversee analytical assays, including imaging, ELISA, Western blotting, and cell-based functional assays, to assess siRNA delivery efficiency and receptor-mediated uptake., • Analyze and interpret data, integrating imaging and functional readouts, and effectively communicate results to internal stakeholders and external collaborators., • Partner with discovery teams to integrate validated in vitro models into RNAi screening and lead optimization workflows. Qualifications • Ph.D. in Cell Biology, Pharmacology, or a related discipline with 6+ years of hands-on industry experience in a biotechnology or pharmaceutical environment., • Demonstrated expertise in ex vivo cell assays, microphysiological systems (MPS), primary and iPSC-derived cell culture, and cell-based functional assays., • Strong understanding of in vitro assay development and the application of 2D and 3D culture systems to model and predict in vivo siRNA delivery, uptake, and activity., • Proven experience with 3D culture platforms, including spheroids, organoids, and co-culture models., • Exceptional organizational and analytical skills, with the ability to independently troubleshoot, optimize, and innovate experimental approaches., • Effective team collaborator and communicator, capable of presenting scientific findings clearly to diverse audiences., • Self-driven and proactive, with the ability to lead projects, manage multiple priorities, and adapt to evolving objectives in a fast-paced environment., • Strong project management and leadership skills, with a proven ability to lead teams and deliver results through cross-functional collaboration., • Experience with oligonucleotide or RNAi-based therapeutics is highly desirable., • #LI-JR1 U.S. Pay Range $147,200.00 - $220,800.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the ___.

< Overview We are seeking an associate scientist-II to join our protein sciences team to contribute to our protein production and conjugation efforts. The candidate must be independent, goal oriented, technically competent, and able to efficiently work across multiple projects. We are searching for enthusiastic, innovative, and highly motivated individuals, with scientific background in protein expression, purification, and analytical techniques, who are comfortable working in a fast-paced entrepreneurial environment.The successful candidate will be part of cross-functional teams including biologists, chemists, and pharmacologists and will contribute to advancing research programs across multiple therapeutic modalities This lab-based position is onsite and will be located at 675 W. Kendall St. Cambridge, MA 02142 Key Responsibilities • Work closely with the protein sciences team to engineer and validate binding of antibodies and antibody conjugates at various production scales., • Design, plan, and perform protein binding experiments to support in vitro and in vivo evaluations, contributing to project-related scientific activities with some guidance from team members., • Utilize UV-Vis spectroscopy and HPLC to analyze, quantify, characterize, and formulate protein conjugates., • Contribute to the maintenance of laboratory infrastructure and equipment., • Support group organization, productivity, and expertise through collaboration and idea exchange., • Meet quality, quantity, and timeline expectations for all assigned projects., • Support discovery efforts in protein sciences., • Maintain accurate and complete electronic notebook records., • Communicate experimental plans and data to multiple cross-functional scientific teams. Qualifications • BS/MS degree in biology, biochemistry, biophysics, chemistry, or a related field, with 0-1 years of relevant laboratory experience in a biopharma or academic setting., • Familiarity with protein and/or antibody structure and function., • Experience with protein binding techniches (ELISA, flow cytometry, SPR and/or BLI) preferred., • Experience with instrumentation such as Octet, Biacore, flow cytometers, and UV-Vis spectrometeters preferred., • Experience with protein and protein conjugate analysis (e.g., affinity chromatography, SEC, IEX, SDS-PAGE, UV-Vis spectroscopy) preferred., • Experience with sterile technique and/or handling mammalian cell culture is a plus., • Passion for driving projects from the bench, independently contributing to research goals, and solving challenging problems., • Detail-oriented, self-motivated, and comfortable working on highly technical projects in a multidisciplinary team setting., • Effective written and oral communication skills. #LI-JR1 U.S. Pay Range $67,600.00 - $101,400.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview We are seeking a highly motivated and skilled Principal Associate Scientist to join our innovative Research & Development (ReDev) team focused on advancing next-generation oligonucleotide-based therapeutics. The ideal candidate will bring extensive hands-on expertise in in vitro assay development, immune cell analysis, and molecular characterization, along with a strong passion for translational science. In this role, you will design and execute complex immune assays, perform high-quality multiparametric flow cytometry, and contribute to the evaluation of nucleic acid-based therapeutic platforms addressing significant unmet medical needs. This position is onsite and will be primarily located in Cambridge, MA. Key Responsibilities • Design, optimize, and execute in vitro and ex vivo immune assays to assess immune modulation, including immune cell activation and suppression using primary and engineered immune cells., • Perform multiparametric flow cytometry (e.g., surface markers, intracellular cytokines, phospho-flow) using platforms such as Cytek Aurora or BD LSR/FACSAria; analyze data using FlowJo, OMIQ, or equivalent tools to assess immune subsets, activation states, and biomarker expression., • Develop and perform ELISA, MSD, cytokine profiling, western blot, and qRT-PCR to evaluate target engagement, gene expression, and knockdown efficiency., • Maintain, expand, and functionally characterize primary immune cells and established mammalian cell lines., • Analyze and interpret multi-parametric datasets (e.g., flow cytometry, cytokine panels, gene expression); summarize results in reports and present data to project teams and cross-functional stakeholders., • Collaborate closely with internal platform teams, contribute to method development, assay validation, and protocol optimization/transfer across functional groups. Qualifications • BS or MS in Immunology, Molecular Biology, Cell Biology, or a related discipline with with 8+ (BS) or 5+ (MS) years of hands-on laboratory experience in a biotech or pharmaceutical setting., • Proven expertise in mammalian primary immune cell isolation, culture, and functional immune assays (e.g., T cell activation, proliferation, cytotoxicity)., • Strong proficiency in flow cytometry, including high-parameter panel design, sample preparation, and data analysis; experience with cell sorting is highly desirable., • Skilled in cell culture, ELISA/MSD, cytokine profiling, Western blotting, and qRT-PCR., • Solid understanding of immune pathways, cell phenotyping, and immune assay readouts., • Familiarity with automation platforms (e.g., liquid handlers, high-throughput systems) is a plus., • Demonstrated ability to independently execute experiments, troubleshoot technical issues, and manage timelines effectively. #LI-JR1 U.S. Pay Range $95,600.00 - $143,400.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Contract Clinical Scientist Our neuro-focused biotech client is seeking an experienced Contract Clinical Scientist to support clinical development activities across ongoing studies. This role is ideal for someone who is detail‑oriented, scientifically strong, and comfortable working in a fast‑paced biotech environment where responsibilities evolve with program needs. Previous experience working with seizure diaries is strongly preferred. Key Responsibilities • Review and confirm patient eligibility based on protocol‑defined criteria, • Perform ongoing clinical data review to ensure completeness, consistency, and quality, • Collaborate with Clinical Operations, Data Management, Medical Monitoring, Biostatistics, and other teams to resolve data issues and protocol deviations, • Maintain clear documentation of eligibility assessments and data review activities, • Lead or support review meetings and communicate findings, • Provide scientific input into study plans and processes, • Participate in team discussions and issue resolution, • Advanced degree (M.S., PharmD, Ph.D., or M.D.) in life sciences or a related field, • 10+ years of experience in clinical development, clinical science, or clinical operations, • Neurology experience preferred, • Strong understanding of FDA/EMA regulations and GCP, • Experience with patient‑level data review, EDC systems, and clinical data review tools, • Ability to work independently and collaboratively in a dynamic environment, • Excellent communication skills and attention to detail, • Strong organizational and time‑management abilities, • Passion for high‑quality work and improving patient outcomes

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s ___ and ___. I further attest that all information I submit in my employment application is true to the best of my knowledge. Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Vice President , Global Clinical Lead - Solid Tumor in our Cambridge office. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Here, you will be a vital contributor to our inspiring, bold mission. OBJECTIVES: Responsible for leading as the Global Clinical Lead a large solid tumor oncology franchise that encompass multiple late stage and early phase programs . Ensures ongoing review and agreement of the Therapy Area Strategy and associated documents formulated by the OTAU leader prior to their review and approval by appropriate governance committees. Oversees the development and execution of the Integrated Disease Area Strategy (IDAS) and overall Integrated Global Development Plan (IGDP). Responsible for review of synopses, other relevant clinical study documents and critical Study Results. Provide leadership and oversight of specific OTAU related programs and if applicable other indication specific clinical leads. Responsible for providing guidance to TA leaders on regional specificities within Therapeutic Area. ACCOUNTABILITIES: • Clinical Development team participation and leadership, • Accountable to Oncology Clinical Science Head to provide strategic clinical input on assigned clinical studies., • Consistent with the Takeda R&D Oncology Therapeutic Area Unit strategy, goals and objectives, this leader will partner with the other key functions and leaders and members of Oncology Precision and Translational Medicine, Oncology Portfolio Strategy Group, Global Regulatory Affairs, Quantitative and Clinical Pharmacology, other R&D Functional Line Oncology Therapeutic Area Leads, Global Product Launch Strategy Oncology Franchise Leads, Regional Oncology Franchise Leads, Oncology Drug Development Unit (DDU) and other Oncology extended leadership, to drive the alignment on global clinical research and development strategy as related to internal and external pipeline and non-pipeline initiatives for the Takeda R&D Oncology Community across all regions, • Part of the Oncology Clinical Sciences Leadership Team providing key input in strategic planning and connectivity for the overall Oncology Clinical Sciences group, • Leads the Global Development Team (US, EU, and others) managing both the US/EU Development Team and the Japan/ China Development team for assigned compounds. In some cases may lead the US/EU Development Team but more likely will oversee the study physician and/or clinical scientist leads responsible for leading the team. Emphasis will be on insuring that the development teams are proactively identifying contingencies, potential risks and strategies to address future obstacles., • Directs Development Team strategy and deliverables overseeing the Development Strategy, Clinical Development Plan and Clinical Protocols. Recommends scope, complexity and size, which influence the budget of all aspects of a program. Provides continual critical evaluation of the development strategy to maintain a state-of-the-art development plan that is competitive and consistent with the latest regulatory requirements, proactive identification of challenges, and development of contingency plans to meet them., • Responsible for high impact global decisions: interpreting data from ongoing internal and external studies, assessing the medical and scientific implications and making recommendations that impact regional and global development such as “go/no go” decisions or modification of development plans or study designs that may have a significant impact on timelines or product labeling. Plans clinical development strategies in context of medical/clinical significance considering how a given product will fit in with current treatments, standard of care, and unmet medical need., • Accountable for ensuring regional strategies and trade-offs in regional requirements are well articulated in the global strategy documentation and that stakeholders are appropriately briefed., • Providing strategic input into global development strategies and plans for all compounds in OTAU., • Providing clinical and strategic support to evaluation of external compounds (alliances and in-licensing opportunities), • Primary interface with Medical Affairs team for strategy and to support of product commercial efforts, • Contributing to the creation and maintenance of regional KOL network, • Providing recommendations for GDT leader nominations and reviewers of external compounds as part of business development efforts, • Liaison with Clinical Operations and Project Management for co-ordination of logistics study planning and implementation, • Synopsis / Protocol Development, Study Execution, & Study Interpretation, • Consistent with membership of the Clinical Review Board Committee, responsible for critical review of synopses, protocols, IBs and relevant clinical documents relating to studies in assigned compounds., • Trial Medical Monitoring, • Reviews and assesses overall safety information in conjunction with Pharmacovigilance and Medical Monitor of record for assigned compounds., • External Interactions, • Oversees and leads all clinical science activities involved in interactions with FDA, other regulatory agencies and key opinion leaders relevant to assigned compounds., • Responsible for evaluation of external interactions in the context of overall development strategies using complex problem solving in the region but in context of a global environment., • Proactive identification of challenges and development of contingency plans as appropriate., • Due Diligence, Business Development and Alliance Projects, • Responsible for evaluation of potential business development opportunities in the region but with the context of a global environment., • Conducts due diligence evaluations, of clinical development plans for potential alliances and or in-licensing opportunities., • Serves as clinical contact point for ongoing alliance projects and interface with partner to achieve Takeda’s strategic goals while striving to maintain good working relationship between Takeda and partner., • Assigns and manages clinical science staff who are involved in many of these activities., • Leadership, Task Force Participation, Upper Management Accountability, • Interacts directly with research division based on pertinent clinical and development expertise and in all aspects relating to assigned compound in regional area. Leads TGRD internal teams and global cross-functional teams. Works with functional leadership to prioritize projects within the therapeutic area., • Hires, manages, mentors, motivates, empowers, develops and retains staff to support assigned activities. Conducts performance reviews and drive goal setting and development planning. EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS: Experience • MD or combined MD/PhD or internationally recognized equivalent with minimum 15 years pharmaceutical research experience, including minimum 10 years late phase clinical development experience with a focus on medical oncology, • Clinical Training and Clinical Experience in Hematology/Oncology and/or Medical Oncology especially in solid tumor malignancies, • Strong depth of scientific and clinical understanding and experience in cancer biology especially in immune based therapies., • Experience in conducting and/ or leading multiple clinical trials involving immune based therapies, • Proven experience in successfully leading and supervising direct reports including several physicians, physician scientists, scientists within a clinical development team in a global matrix environment., • Demonstrated ability to foster a high-performance culture and build organizational capabilities., • Strong leadership commitment to diversity, equity and inclusion, with experience in creating an inclusive and collaborative team environment that leverages diverse perspectives., • Previous experience in successfully leading several clinical development team/matrix team with responsibility for Global studies in multiple regions. Clinical Development experience beyond US/EU, • Solid and Multiple experience in preparing and interacting with multiple regulatory agencies including FDA, EMA, and others, • Multiple NDA/MAA submission experience, • Proven ability to lead and manage highly trained medical, scientific, and technical professionals., • Superior communication, strategic, interpersonal and negotiating skills, • Enterprise level leadership with the ability to inspire, motivate and drive results, • Excellent communication both verbally and in writing and influencing skills, with the ability to engage, inspire, and influence stakeholders at all levels, including executive management and external partners., • Ability to proactively predict issues and solve problems, • Ability to drive decision-making within a multi-disciplinary, multi-regional, matrix teams, • Diplomacy and positive influencing abilities across multinational business cultures TRAVEL REQUIREMENTS: • Willingness to travel to various meetings or client sites, including overnight trips. Several international travels may be required., • Requires approximately 25-35 % travel. Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy. #LI-JT1 Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $307,300.00 - $482,900.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Boston, MA Employee Regular Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Medford Campus Sep 23, 2025 $8,530 Tufts Gordon Institute has openings for part-time lecturers at the graduate level to teach a 7-week course EM 252 Business Communications. The part-time lecturer would be teaching an existing course that already has a fully developed curriculum. Preference for teaching the course in person on the Tufts Medford campus, but the possibility to teach online could also be considered. Based within the School of Engineering, the Gordon Institute at Tufts University provides students with the knowledge and skills they need to lead both teams and entire companies through programs taught by faculty who have excelled in industry. TGI develops leaders by bringing together diverse perspectives to tackle real-world challenges. This cross-disciplinary approach enriches how we teach applied business-where technical expertise meets strategic thinking meets human insight. Course Overview Being an effective, inclusive communicator is an essential part of being a successful scientist, engineer, or technical professional. Effective communication is the only way to share the results of your work, to collaborate, to innovate, and to meet your ethical obligations as a practicing professional. You will learn methods to plan and deliver effective business presentations for diverse audiences, including creating clear, engaging slides and data graphics. You will practice and gain confidence in public speaking for in-person and virtual formats. Course Topics • Principles of effective business communication, • Public speaking and delivery of presentations, • Planning content and organization for a presentation, • Design of PowerPoint slides, • Data graphics, • Accessibility in presentations, • Virtual presentations, • Group presentations, • Managing meetings, • Storytelling to engage the audience, • Inclusive presentations for diverse audiences In-Person Format: Either one 3-hour class session or two 90-minutes class sessions per week Online Format: Primarily asynchronous course with once-per-week synchronous online meetings of 45-60 minutes. The ideal candidate has professional experience in communications, leadership, and/or management in an engineering or technical field and previous college-level teaching experience preferred. Candidates should submit their application, including a cover letter, resume, statement of teaching interests through Interfolio. Candidates are encouraged to demonstrate attention to diversity and inclusion as it relates to teaching, research, and scholarship throughout their application. Compensation: The compensation for this part-time Lecturer position in the Tufts Gordon Institute is $8,530 per 2 SHU course.

Job Description Summary LI# Hybrid Internal Job Title: Expert Data Science / Senior Expert Data Science Location: East Hanover, NJ, Cambridge, MA or Durham, NC This position will be located at the East Hanover, NJ, Durham NC, or Cambridge, MA site and will not have the ability to be located remotely. Please note that this role would not provide relocation and only local candidates will be considered. Job Description: We are seeking a talented and motivated Data Scientist to join the Data and Statistical Sciences team within the Novartis Cell and Gene Therapy Scientific Office. The Data and Statistical Sciences team advances Novartis's goal of bringing safe and efficacious cell and gene therapies to market through supporting development scientists with data infrastructure, analytics, and a vision for the future of digital-enabled therapeutic development. The successful candidate will play a key role in establishing data flows and connections from laboratory systems to data science platforms, advancing our understanding of bioprocesses, and contributing to the optimization and improvement of our development processes. Job Description Responsibilities: • Lead efforts to establish data flows and connections from laboratory systems to our data science platform., • Drive cross-functional collaboration across various business domains, including IT, engineering, laboratory teams, to identify data sources and develop data extraction methods that ensure data integrity and security., • Quickly learn the use of tools, data sources, and analytical techniques needed to answer a wide range of critical business and scientific questions., • Design and implement data pipelines to ingest, clean, and transform raw data for analysis., • Leverage statistical and machine learning techniques to analyze integrated data sets, both structured and unstructured, extracting valuable insights into biopharmaceutical manufacturing processes., • Communicate analytical findings to business users through compelling business presentations, interactive visualization tools, and contextual storytelling techniques, ensuring a clear and impactful understanding of the derived insights from data analysis., • Develop and maintain data models and schemas to support ongoing data analysis and reporting needs., • Be adaptable in providing support for a wide array of assessments, including process comparability, when necessary., • Stay abreast of advancements in data technologies and best practices, recommending and implementing improvements to data infrastructure, models, and techniques as needed. This is a dual posting. The final level & title of the offer role would be determined by the hiring team based on the skills, experience & capabilities required to perform the role at the level the role has been offered (Expert Data Science OR Senior Expert Data Science): Expert Level: A minimum of a Bachelor's Degree with 4 years / Masters Degree with 2 years / Recent PhD. A combination of relevant industry experience and education will also be considered. Training and experience demonstrating proficiency in data management will be valued. Senior Expert Level: A minimum of Bachelor's Degree with 7 years / Masters Degree with 5 years/ PhD with 2 years of experience or dedicated postdoc / graduate training in the field of bioprocess or data science. A combination of relevant industry experience and education will also be considered. Training and experience demonstrating proficiency in data management will be valued. • Proficiency in programming languages such as Python or R., • Strong understanding of modeling and statistical concepts., • Excellent teamwork and communication skills, with a collaborative and proactive approach to problem-solving., • Knowledge of bioprocess engineering and biopharmaceutical manufacturing, with optional experience in cell or gene therapy (lentiviral or adenoviral technology)., • Experience with app development platforms like Red Hat OpenShift or Posit Connect is preferred., • Familiarity with web development technologies including JSON, CSS, and HTML is preferred., • Experience with tools and platforms commonly used in the biopharmaceutical industry (e.g., JMP/JSL/SAS, SIMCA, AVEVA PI) is strongly preferred. The salary for this position is expected to range as follows: Expert Data Science: $103,600 and $192,400 per year Senior Expert Data Science: $119,700 and $222,300 per year The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click ___. EEO Statement: The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility and reasonable accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Salary Range $103,600.00 - $192,400.00 Skills Desired Clinical Trials, Computer Programming, Data Analysis, Programming Languages, Reporting, Statistical Analysis

About the Job Senior Scientist, Clinical Development is a scientist with translational expertise leading key scientific studies from concept through to publication, focused on value of FMI’s products in clinical practice and oncology drug development. This role executes on strategic scientific collaborations involving a range of functions and external collaborators, driving studies that establish the clinical validity and utility of products and biomarkers aligned to Clinical Development Plans and FMI enterprise strategy. Working with Clinical Development leadership, this position will execute analysis for and lead studies through conceptualization, narrative building, and writing using clinical cohorts or real-world evidence. This position will also contribute to department strategy and will generate and present evidence to inform biomarker and product prioritization and development. Key Responsibilities • Execute analysis and interpret data for multiple projects and publications supporting Clinical Development Plans (CDPs) and establishing clinical validity and clinical utility of our products., • Lead projects through submission including layout key objectives, figures, and narrative for abstracts and manuscripts, and solicit and incorporate input from key stakeholders with minimal guidance from CDP leads., • Conduct translational research to develop insights into predictive and prognostic biomarkers., • Leverage FMI’s clinical and genomic datasets to link genomic findings with clinical outcomes., • Contribute to protocol and SAP design and review for studies led by Clinical Development., • Support collaboration cross-functionally with internal and external stakeholders and thought leaders (academic and biopharma)., • Ensure studies further the strategic evidence needs of FMI products., • Manage and establish beneficial collaborations with key opinion leaders in oncology., • Continually develop deep domain expertise in genomics from a scientific, clinical and technical standpoint and lend insights to cross-functional teams to further the development of our products and strategy., • Maintain availability to the wider FMI business for clinical development expertise, presenting information and evidence to scientific, medical legal, commercial or other stakeholders as appropriate., • Maintain and deepen disease area-specific clinical and data science expertise., • Build awareness of biomarker and product development and department and business strategy and evaluate strategic alignment and priority of new projects., • Other duties as assigned. Qualifications: Basic Qualifications: • Master’s Degree in life sciences and 7+ year(s) of experience in clinical outcomes and/or genomics in an academic or life sciences industry setting, OR, • Doctorate Degree or Ph.D. in a life science and 5+ year(s) of experience in clinical outcomes and/or genomics in an academic or life sciences industry setting Preferred Qualifications:, • Proficiency with one or more script languages (Python, Perl, etc.) and statistical software package (R, SAS), • Demonstrated experience designing and executing analyses in cancer genomics, • Expertise in translational research linking genomic biomarkers with clinical outcomes, • Experience leading biomedical data analysis (genomics data, clinical outcomes, real-world data, liquid biopsy, RNA and protein expression), • Experience with communicating with academic scientists and treating physicians, • Track record of taking projects from concept to completion, • Lead-authored publications, and demonstrated excellence in writing, • Ability to work independently as well as collaborate and communicate effectively with cross-functional teams; drive agendas, lead discussions, and drive results on cross-functional teams, • Knowledge of oncology, next-generation sequencing, clinical trials, and/or companion diagnostics., • Experience with oncology diagnostic development and product development and validation, • Demonstrated ability to successfully manage multiple concurrent projects in a fast-paced, dynamic environment, • Excellent organizational skills and meticulous attention to detail, • Demonstrated ability to think creatively and problem solve, • Extremely high level of integrity and reliability, • Excellent presentation skills, • Willingness to adhere to all applicable FMI Standard Operating Procedures, policies, processes, and compliance guidelines, • Understanding of HIPAA and the importance of patient data privacy, • Commitment to FMIs values: Integrity, Courage, and Passion The expected salary range for this position based on the primary location of Boston, MA is $143,000 - $179,000 per year. The salary range is commensurate with Foundation Medicine's compensation practice and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for Foundation Medicine's benefits. #LI-Hybrid

Job DescriptionSalary: $143,000 - $164,000 Summary The Scientist, Preclinical Development is responsible for supporting activities related to transitioning drug development candidates from research into early development to enable clinical studies. Visterra is seeking a flexible candidate with broad-based knowledge of immunology; knowledge/experience in antibody therapeutics and preclinical development are preferred but not required. This role will be responsible for activities related to drug development candidates. They will be expected to design and perform in vitro and ex vivo cell-based assays in lab to support the evaluation of specificity and safety of drug development candidates. They will assist in advancing the teams understanding of programs transitioning from research to development, which includes working cross-functionally with research teams to understand the biology of targets, as well as performing independent literature research on target pharmacology, diseases of interest, and key/relevant biomarkers to support program development. The ideal candidate would have a Ph.D in biochemistry, molecular biology, immunology or related field with 0-3 years of experience post-graduation, although candidates with a B.S. or M.S. in these fields who have at least 5 years of research experience in either academic or biotech settings- particularly those with experience in antibody therapeutics- are also encouraged to apply. This is a full-time position based on-site at Visterras facility in Waltham, MA, with anywhere from 20-80% of time allocated to working in the lab, based on departmental and program needs. Responsibilities • Work cross-functionally with research teams to support transfer of program knowledge and assays from research to development, • Conduct specificity/binding experiments, ex vivo cytokine secretion assays, potency and other cell-based functional assays to help characterize and support new programs entering the development phase, • Designs, analyzes and interprets quantitative pharmacology and in vitro, ex vivo and in vivo PK/PD/RO studies and communicates results to teams and management., • Review, analyze, graph, interpret and present data at internal and/or cross functional team meetings, • Write/review study reports to support IND or CTA filings, • Provide support for regulatory submissions as needed, • Perform independent literature reviews on relevant diseases, biomarkers, and therapeutics to advance understanding of nonclinical programs, • Oversee external contractors to leverage appropriate preclinical in-vitro and in-vivo models and procedures to support development programs., • Other duties and responsibilities as required by departmental and business needs Requirements • At least 5 years of research experience, either in an academic or biotech setting; experience with biologics is highly desirable, • An M.S. or Ph.D. in Immunology, Biology, Biochemistry, or related field is preferable, although candidates with a Bachelor of Science (BS) degree with significant research experience are also encouraged to apply, • Ability to execute and troubleshoot experiments independently, document results, and perform quality review of data from both internal and outsourced studies, • Excellent written and verbal communication skills, • Demonstrated ability to perform as a team player and complete tasks according to established deadlines, • The ability to think critically, synthesize and extract simple principles from complex datasets, communicate effectively across a broad spectrum of audiences, • Familiarity with Microsoft Office, including Teams, as well as Prism GraphPad preferred, • Limited travel to attend conferences and/or industry events that support the candidates professional development will be expected (<5%) Company Visterra is a clinical stage biotechnology company committed to developing innovative antibody-based therapies for the treatment of patients with kidney, immune-mediated and other hard-to-treat diseases. Our proprietary technology platform enables the design and engineering of precision antibody-based product candidates that specifically bind to, and modulate, key disease targets. Applying this technology to disease targets that are not adequately addressed by traditional therapeutic approaches, we are developing a robust pipeline of novel therapies for patients with unmet needs. Visterras pipeline has multiple clinical-stage assets and one approved therapeutic, sibeprenlimab. As a member of the Otsuka family of companies, we are uniquely positioned as a small, dynamic, nimble and innovative organization where individuals and teams are empowered to make big impacts while benefiting from the support, strength, stability and long-term perspective of a 100-year-old global company. Visterra has approximately 105 employees and is located in Waltham, Massachusetts. Visterra provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

Job DescriptionAbout Synolo Therapeutics:Synolo Therapeutics, an early-stage biotechnology company launched by RA Ventures, is pioneering the development of precision-targeted immunotherapies for cancer. Powered by computational protein design and proprietary technologies that yield biological data sets at unprecedented scale and resolution, we are building a pipeline of first-in-class multi-specific biologics with novel functionalities. Synolo was founded by pioneers in the field of protein design and engineering, synthetic biology, DNA sequencing, immunology, and biologics drug discovery and development. About RA Capital:RA Capital Management funds and builds healthcare and life science companies using an evidence-based investment approach informed by TechAtlas, a think tank within RA Capital which analyzes scientific and clinical data from academic literature and industry sources to anticipate how breakthroughs might impact industry stakeholders, physicians, patients, and policymakers. TechAtlas' analyses are captured in a unique collection of competitive landscapes, or ‘maps’, that identify competitive therapeutics, diagnostics, research tools, and/or technological capabilities in a given area. About the Role:Synolo Therapeutics is seeking a collaborative and technically strong Senior Scientist or Principal Scientist to join our Biologics Discovery team. This role is a great fit for an antibody discovery and engineering expert who enjoys hands-on work at the bench, leads through influence and scientific excellence, and thrives in a fast-moving, early-stage biotech environment. In this role, you will play a key part in advancing Synolo’s in-house biologics platform, including the discovery, engineering, and characterization of multispecific antibody therapeutics. You will have meaningful ownership of scientific direction and execution, working closely with cross-functional partners across discovery and development. As a member of a highly engaged team, you will help shape scientific strategy, support strong execution, and contribute to a collaborative, thoughtful, and results-driven culture.Key Responsibilities: • Drive discovery and platform efforts: Lead research activities within the in-house biologics team, achieve project milestones, and advance platform development for biologic discovery and multispecific antibody engineering., • Design and build libraries: Develop antibody libraries using in silico and rational approaches, • Antibody isolation and optimization: Experimentally isolate antibodies with desired properties through discovery workflows and analyze antibody sequences resulting from these workflows. Improve antibody leads through humanization, affinity maturation/optimization, and other engineering strategies to enhance performance and overall quality. Partner with Protein Science and Immunology teams to design, engineer, and refine multi-specific antibody constructs to maximize functionality, • Communicate and collaborate: Present results, recommendations, and next steps to project teams and cross-functional stakeholders to drive alignment, momentum, and program success.Qualifications & Skills:, • Strong knowledge of canonical antibody sequence classes and structural concepts, including experience with alternative formats such as scFvs, VHHs, and multispecific formats., • Hands-on expertise with yeast or phage display methods for antibody engineering, including library construction, panning/sorting, and sequence analysis., • Proficiency with next-generation sequencing (NGS) and its application to antibody discovery and optimization workflows., • Experience with handling significant numbers of sequences and related data, and proficiency in software to process antibody sequence-related data (Geneious Biologics, PipeBio, etc.), • Excellent communication and interpersonal skills, with the ability to build productive working relationships across functions and with external contractors, consultants, and CROs.Education & Experience:, • We recognize that great careers aren’t always linear and welcome applicants from a variety of backgrounds., • PhD, MS, or BS in Biochemistry, Molecular Biology, Biomedical Engineering, Chemical Engineering, or a related field, with a minimum of 12 years (BS), 8 years (MS), or 3 years (PhD) of relevant industry experience., • Title will be commensurate with experience.Preferred Experience:, • Experience interfacing with protein design scientists and ML-related workflows, • Experience with automation and automated workflows for both data-handling and liquid-handling systems

Job DescriptionAt Toyota Research Institute (TRI), we’re on a mission to improve the quality of human life. We’re developing new tools and capabilities to amplify the human experience. To lead this ground-breaking shift in mobility, we’ve built an extraordinary team in Automated Driving, Energy & Materials, Human-Centered AI, Human Interactive Driving, Large Behavioral Models, and Robotics. The MissionMake general-purpose robots a reality. The ChallengeWe envision a future where robots assist with household chores and cooking, aid the older population in maintaining their independence, and enable people to spend more time on the activities they enjoy most. To achieve this, robots need to be able to operate optimally in messy, unstructured environments. Our mission is to answer the question “What will it take to create truly general-purpose robots that can accomplish a wide variety of tasks in settings like human homes with minimal human supervision?”. We believe the answer lies in cultivating large-scale datasets of physical interactions from diverse sources and using the latest advances in machine learning to learn general-purpose robot behaviors from them. The TeamOur goal is to revolutionize the field of robotic manipulation, enabling long-horizon dexterous behaviors to be efficiently taught, learned, and improved over time in diverse, real-world environments.Our team has deep multi-functional expertise across hardware, simulation, perception, controls, and machine learning, and we measure our success in terms of fundamental capabilities' development, as well as research impact via open-source software and publications. Our north star is fundamental technological advancement in building robots, which can flexibly perform a wide variety of tasks in diverse environments with minimal human supervision. Come join us and let’s make general-purpose robots a reality. Some of our ongoing work is highlighted here. The OpportunityWe’re looking for a driven research scientist or research engineer with a strong background in embodied machine learning and a “make it happen” mentality. The ideal candidate is able to work independently when needed, but works well witha larger integrated group at the latest of state-of-the-art robotics and machine learning. Experience with robots or other embodied systems (such as autonomous vehicles) is strongly preferred, particularly in the manipulation domain.If our mission of revolutionizing robotics through machine learning resonates with you, then let’s talk about how we can create the next generation of AI-powered capable robots together.Responsibilities • Work as part of a dynamic, closely-knit research team building useful robots and general-purpose robot foundation models., • Implement, extend, and create innovative methods for robot behavior learning from a mixture of interactive embodied data and online data sources., • Design and implement high-performance machine-learning pipelines and optimize data and learning stacks for scalability, efficiency, and performance., • Be a key member of the team and play a critical role in rapid progress measured by both the development of internal capabilities and high-impact external publication., • Collaborate with internal research scientists and our partner labs at top academic research universities including MIT, Stanford, Berkeley, CMU, Columbia, and Princeton to drive pioneering research at scale.Qualifications, • 4+ years of relevant industry experience or a PhD., • Experience training large models and deploying them on embodied systems., • Strong software development skills in Python, familiarity with mixed C++/Python codebases, and a focus on clean, maintainable code., • Extensive experience with Machine Learning using a major framework such as PyTorch or TensorFlow. Familiarity with data pipelines, model serving and optimization, cloud training, and dataset management., • Strong understanding of the state-of-the-art in robot learning, including vision-language-action (VLA) models, reinforcement learning, and/or computer vision., • Practical experience with robots and the system integration challenges inherent in conducting research and deploying onto physical hardware platforms., • An ability to adapt quickly and switch between modes of rapid prototyping and robust implementation as required., • A consistent track record of impact, either via first author research publications at top-tier machine learning or robotics conferences (RSS, NeuRIPS, ICML, ICLR, CoRL, ICRA, IROS, …), or via relevant contributions to successful industry initiatives.Bonus Qualifications, • Experience with robotic middleware such as ROS 2 and common communication methods and protocols., • Experience with modern ML infrastructure pipelines, approaches, and tools., • Experience with VR-based teleoperation for real-time robot control.

Job DescriptionAbout SimpliSafe SimpliSafe is a leading innovator in home security, on a mission to make every home a safe home. We build user-centric hardware, software, and services that protect what matters most, with a hybrid work model and a highly collaborative, low-ego culture. We're embracing a hybrid work model that enables our teams to split their time between office and home. Hybrid for us means we expect our teams to come together in our state-of-the-art office on two core days, typically Tuesday, Wednesday, or Thursday – working together in person and choosing where they work for the remainder of the week. We all benefit from flexibility and get to use the best of both worlds to get our work done. Why are we hiring? Well, we're growing and thriving. So, we need smart, talented, and humble people who share our values to join us as we disrupt the home security space and relentlessly pursue our mission of keeping Every Home Secure. Why this role exists We're scaling AI and machine learning across our products, devices, and operations. To do this well, we need a Principal Product Manager who understands not only how to apply AI in user experiences, but also how models, data, and pipelines are built, deployed, and operated in production—including on resource-constrained, edge hardware. You will lead our highest-impact AI initiatives end-to-end: defining where to invest, shaping model and data requirements, partnering with MLOps and ML engineering on deployment (cloud and edge), and driving continuous improvement after launch. What you'll own • Vision & strategy, • Define and communicate the multi-year roadmap for key AI/ML capabilities across SimpliSafe., • Identify and prioritize AI opportunities where models and data can materially improve safety, customer experience, or efficiency—on both devices and cloud services., • Make build-vs-buy decisions for AI capabilities in partnership with data science and engineering., • End-to-end AI systems (cloud & edge), • Partner with data scientists, ML engineers, and MLOps to design and deliver end-to-end ML solutions—from problem framing through data, training, evaluation, deployment, and monitoring., • Work with hardware and embedded teams to shape edge AI/ML experiences (e.g., on-device detection, low-latency decisions, bandwidth-aware designs)., • Define model-level requirements (metrics, latency, cost, guardrails) and connect them to business outcomes (e.g., false alarm reduction, detection accuracy, handle time, CSAT)., • Translate product needs into requirements for ML platform capabilities (model serving, observability, experiment tracking, human-in-the-loop tools)., • Generative AI & LLMs, • Lead product direction for LLM and multimodal use cases (e.g., text, vision, sensor data)., • Decide when to use prompt engineering, RAG, fine-tuning, or traditional ML—and how to evaluate quality, safety, and hallucinations., • Design workflows that incorporate human review and escalation where needed., • Execution & leadership, • Drive cross-functional execution across product, engineering, data science, hardware/firmware, operations, and go-to-market., • Establish feedback loops (customer feedback, annotation programs, operational input) and use them to guide retraining and iteration., • Operate at Principal level: set direction across multiple teams and mentor other PMs., • Risk, ethics & communication, • Ensure ethical and responsible use of AI, including privacy, bias, explainability, and safety guardrails., • Communicate how AI systems work, their benefits, and their limitations to executives and non-technical stakeholders.What we're looking for, • 8+ years of product management experience, including significant ownership of AI/ML or data-intensive products., • Clear track record of shipping production ML systems (not just integrating third-party AI APIs), in close partnership with data science, ML engineering, and MLOps., • Principal-level impact: leading cross-team initiatives, shaping strategy, and influencing senior stakeholders., • Strong understanding of core ML concepts and lifecycle: data, labeling, training/validation, evaluation metrics, deployment, monitoring, and retraining., • ML experience with at least one of following: computer vision or sensor data, LLM-powered applications (prompting, RAG, fine-tuning, evaluation) and/or hardware or edge products (e.g., on-device models, connectivity/latency trade-offs)., • Familiarity with modern ML infrastructure (cloud platforms, model serving, CI/CD for ML, monitoring/alerting)., • Comfortable going deep into data, metrics, and model behavior—not just the UX layer., • Excellent communicator who can make complex AI topics clear to diverse audiences., • Prior hands-on experience as a data scientist, ML engineer, or MLOps engineer., • Experience with ML platforms (feature stores, pipeline orchestration, experiment tracking)., • Experience in regulated or safety-critical environments.About You, • You are excited to go deep under the hood: data, pipelines, model choices, failure modes—not just the UX layer., • You're comfortable in non-deterministic environments where experiments fail, models drift, and iteration is the norm., • You combine data-driven decision making with sound judgment when data is incomplete., • You're an exceptional communicator who can explain complex AI systems to diverse audiences and bring them along in the decision., • You lead through influence, building alignment across product, engineering, data science, operations, and leadership., • You are a continuous learner who keeps up with AI/ML advancements and can distinguish lasting foundations from short-lived hype.What Values You'll Share, • Customer Obsessed – Building deep empathy for our customers, putting them at the core of our work, and developing strong, long-term relationships with them., • Aim High – Always challenging ourselves and others to raise the bar., • No Ego – Maintaining a "no job too small" attitude, and an open, inclusive, and humble style., • One Team – Taking a highly collaborative approach to achieving success., • Lift As We Climb – Investing in developing others and helping those around us succeed., • Lean & Nimble – Working with agility and efficiency to experiment in an often ambiguous environment.What We Offer, • A mission- and values-driven culture and a safe, inclusive environment where you can build, grow, and thrive., • A comprehensive total rewards package that supports your wellness and provides security for SimpliSafers and their families., • Free SimpliSafe system and professional monitoring for your home. This target annual base pay range represents our good-faith estimate of what we expect to pay for this role. We use a market-based compensation approach to set our target annual base pay ranges and make adjustments annually. We carefully tailor individual compensation packages, including base pay, taking into consideration employees' job-related skills, experience, qualifications, work location, and other relevant business factors. Beyond base pay, we offer a Total Rewards package that may include participation in our annual bonus program, equity, and other forms of compensation, in addition to a full range of medical, retirement, and lifestyle benefits. More details can be found here. We're committed to fair and equitable pay practices, as well as pay transparency. We regularly review our programs to ensure they remain competitive and aligned with our values. We wholeheartedly embrace and actively seek applications from all individuals, no matter how they identify. We are committed to cultivating a diverse and inclusive workplace, and we believe our work is enriched when we incorporate a multitude of perspectives, backgrounds, and experiences. We want everyone who works here to thrive and contribute to not only our mission of keeping every home secure, but also to making our workplace safe and supportive for others. If a reasonable accommodation may be needed to fully participate in the job application or interview process, to perform the essential functions of a position, or to receive other benefits and privileges of employment, please contact .

Job Description Shift is the leading AI platform for insurance. Shift combines generative, agentic, and predictive AI to transform underwriting, claims, and fraud and risk - driving operational efficiency, exceptional customer experiences and measurable business impact. Trusted by the world's leading insurers, Shift delivers AI when and where it matters most, at scale and with proven results. Our culture is built on innovation, trust, and a drive to transform the insurance industry through our SaaS platform. We come from more than 50 different countries and cultures and together we are creating the future of insurance. About the Team • This role is part of our Data Science team which is the largest team in our organization consisting of over 200+ Data Scientists throughout the world., • Our Data Scientists work in a full lifecycle role and on a broad range of subjects acquiring extensive technical and professional experience in data science, data engineering, coding, business understanding and client engagement., • Our company is small enough that each person's achievements has an impact on our overall performance, yet big enough to be a world leader and innovator in our domain., • Your role will be to actively contribute to the US- Insurance roadmap and clients, and working on various data types such as structured data, free text, documents and images., • Build and productionize data pipelines (structured, text, documents, images) optimized for LLMs and multi-modal models., • Design, develop and deploy LLM-based solutions (RAG, embeddings, instruction tuning) for subrogation, claims handling, document understanding, and related use cases., • Experiment with the latest in Agentic AI technologies (Langchain/Langgraph, OpenAI Agent SDK, MCP, A2A) and develop MVP for the next generation of autonomous subrogation solutions., • Develop "Chain-of-Thought" and "ReAct" prompting strategies to ensure the agent can justify its liability percentages based on the Comparative Negligence laws of different jurisdictions., • Create custom "tools" for the agent, allowing it to query internal databases, call external weather APIs, or calculate impact force based on telemetry data., • Establish rigorous evaluation frameworks (LLM-as-a-judge) to ensure the agent's decisions are unbiased, legally sound, and explainable., • Ensure responsible-AI practices: privacy, hallucination mitigation, explainability and compliance. We are looking for candidates with diverse skills to help us build excellent technology solutions for our clients and be proficient in the following skills: • Expert proficiency in production-level object-oriented programming (OOP) for building scalable and reliable systems., • Proven hands-on experience with Large Language Models (LLMs) and generative AI techniques (including RAG, embeddings, prompt engineering, and model tuning), leveraging frameworks such as OpenAI/Anthropic or open-source variants., • Solid foundation in ML fundamentals with practical experience in the full machine learning lifecycle, including model evaluation, monitoring, versioning, and deployment in production environments., • Experience designing and implementing robust data pipelines for document, OCR, and multi-modal data workflows., • Agentic Frameworks: Experience with integrating frameworks like LangChain/LangGraph, OpenAI Agent SDK, CrewAI, A2A/MCP with Databricks or Azure-hosted models (e.g., DBRX, OpenAI GPT-5.3, Anthropic Claude, Google Gemini)., • Databricks Ecosystem: Deep expertise in Mosaic AI (formerly MosaicML), Unity Catalog, and Delta Lake. Good understanding of Spark data architecture is a plus., • Experience using MLflow for the full lifecycle: from experiment tracking and prompt engineering in the AI Playground to model evaluation. #LI-MG1 #LI-HYBRID The range listed is for base compensation. Your actual base salary will vary based on factors including location and individual qualifications objectively assessed during the interview process. In addition to base salary, your total rewards package will include additional components such as incentive pay, equity, and benefits. If you're interviewing for this role, speak with your Talent Acquisition Partner to learn more about the specific details for this position. US Base Salary Pay Range$80,000—$110,000 USD To support our permanent, full time employees at every stage of their careers and lives, we provide a competitive total rewards and benefits package. Here are the global benefits we'd like to highlight: • Flexible remote and hybrid working options, • Competitive Salary and a variable component tied to personal and company performance, • Multiple Learning and Development opportunities, including Focus Fridays, a half-day each month to focus on learning and personal growth, • Generous PTO and paid holidays, • Mental health benefits At Shift we strive to be a diverse and inclusive workforce. We welcome applications from and hire people who will contribute to the diversity of our company, without regard to race, color, religion, marital status, age, national or ethnic origin, physical or mental disability, medical condition, pregnancy, genetic information, gender identity or expression, sexual orientation, or other non-merit criteria. Shift Technology is committed to providing reasonable accommodations for qualified individuals with disabilities in our application and employment process. Should you require accommodation, please email and we will work with you to meet your accessibility needs. Please be aware of scammers and only trust correspondence that comes from emails ending in "shift-technology.com". We will never do initial outreach to you via Whatsapp/Text/SMS, never ask for banking information or personal identification numbers (ex. Social Security Number) as part of our recruitment process. Shift Technology does not accept unsolicited CVs from recruiters or employment agencies in response to the Shift Technology Careers page or a Shift Technology social media post. Any unsolicited CVs, including those submitted directly to hiring managers, are deemed to be the property of Shift Technology.

Job Description Shift is the leading AI platform for insurance. Shift combines generative, agentic, and predictive AI to transform underwriting, claims, and fraud and risk - driving operational efficiency, exceptional customer experiences and measurable business impact. Trusted by the world's leading insurers, Shift delivers AI when and where it matters most, at scale and with proven results. Our culture is built on innovation, trust, and a drive to transform the insurance industry through our SaaS platform. We come from more than 50 different countries and cultures and together we are creating the future of insurance. About the Team • This role is part of our Data Science team which is the largest team in our organization consisting of over 200+ Data Scientists throughout the world., • Our Data Scientists work in a full lifecycle role and on a broad range of subjects acquiring extensive technical and professional experience in data science, data engineering, coding, business understanding and client engagement., • Our company is small enough that each person's achievements have an impact on our overall performance, yet big enough to be a world leader and innovator in our domain., • Your role will be to actively contribute to the US Health roadmap and clients, and working on various data types such as structured claims data, free text, documents and images., • Build and productionize data pipelines (structured, text, documents, images) optimized for LLMs and multi-modal models., • Design, develop and deploy LLM-based solutions (RAG, embeddings, instruction tuning) for claims handling, document understanding, and related use cases., • Experiment with the latest in Agentic AI technologies (Langchain/Langgraph, OpenAI Agent SDK, MCP, A2A) and develop MVP for the next generation of payment integrity solutions., • Create custom "tools" for the agent, allowing it to query internal databases, call external weather APIs, or calculate impact force based on telemetry data., • Establish rigorous evaluation frameworks (LLM-as-a-judge) to ensure the agent's decisions are unbiased, legally sound, and explainable., • Ensure responsible-AI practices: privacy, hallucination mitigation, explainability and compliance. We are looking for candidates with diverse skills to help us build excellent technology solutions for our clients and be proficient in the following skills: • Expert proficiency in production-level object-oriented programming (OOP) for building scalable and reliable systems., • Proven hands-on experience with Large Language Models (LLMs) and generative AI techniques (including RAG, embeddings, prompt engineering, and model tuning), leveraging frameworks such as OpenAI/Anthropic or open-source variants., • Solid foundation in ML fundamentals with practical experience in the full machine learning lifecycle, including model evaluation, monitoring, versioning, and deployment in production environments., • Experience designing and implementing robust data pipelines for document, OCR, and multi-modal data workflows., • Agentic Frameworks: Experience with integrating frameworks like LangChain/LangGraph, OpenAI Agent SDK, CrewAI, A2A/MCP with Databricks or Azure-hosted models (e.g., DBRX, OpenAI GPT-5.3, Anthropic Claude, Google Gemini)., • Databricks Ecosystem: Deep expertise in Mosaic AI (formerly MosaicML), Unity Catalog, and Delta Lake. Good understanding of Spark data architecture is a plus., • Experience using MLflow for the full lifecycle: from experiment tracking and prompt engineering in the AI Playground to model evaluation. #LI-MG1 #LI-HYBRID The range listed is for base compensation. Your actual base salary will vary based on factors including location and individual qualifications objectively assessed during the interview process. In addition to base salary, your total rewards package will include additional components such as incentive pay, equity, and benefits. If you're interviewing for this role, speak with your Talent Acquisition Partner to learn more about the specific details for this position. US Base Salary Pay Range$90,000—$115,000 USD To support our permanent, full time employees at every stage of their careers and lives, we provide a competitive total rewards and benefits package. Here are the global benefits we'd like to highlight: • Flexible remote and hybrid working options, • Competitive Salary and a variable component tied to personal and company performance, • Multiple Learning and Development opportunities, including Focus Fridays, a half-day each month to focus on learning and personal growth, • Generous PTO and paid holidays, • Mental health benefits At Shift we strive to be a diverse and inclusive workforce. We welcome applications from and hire people who will contribute to the diversity of our company, without regard to race, color, religion, marital status, age, national or ethnic origin, physical or mental disability, medical condition, pregnancy, genetic information, gender identity or expression, sexual orientation, or other non-merit criteria. Shift Technology is committed to providing reasonable accommodations for qualified individuals with disabilities in our application and employment process. Should you require accommodation, please email and we will work with you to meet your accessibility needs. Please be aware of scammers and only trust correspondence that comes from emails ending in "shift-technology.com". We will never do initial outreach to you via Whatsapp/Text/SMS, never ask for banking information or personal identification numbers (ex. Social Security Number) as part of our recruitment process. Shift Technology does not accept unsolicited CVs from recruiters or employment agencies in response to the Shift Technology Careers page or a Shift Technology social media post. Any unsolicited CVs, including those submitted directly to hiring managers, are deemed to be the property of Shift Technology.

Senior Data Scientist with the following duties: collaborate with a diverse set of users and partners across multiple functions to translate unstructured, complex business problems into appropriate data, modelling and analytical solutions; lead data science projects through the data, analytics & mac

Medford Campus Oct 09, 2025 $12,035 Tufts Gordon Institute has openings for part-time lecturers at the undergraduate level to teach EM 52: Technical and Managerial Communication. The part-time lecturer would be teaching an existing course with fully developed curriculum and working with a team of other part-time and full-time faculty teaching the same course. Responsibilities include attending weekly online meetings with the faculty team, leading engaging class sessions, providing feedback on assignments, and supporting student learning through office hours. Based within the School of Engineering, the Gordon Institute at Tufts University provides students with the knowledge and skills they need to lead both teams and entire companies through programs taught by faculty who have excelled in industry. TGI develops leaders by bringing together diverse perspectives to tackle real-world challenges. This cross-disciplinary approach enriches how we teach applied business-where technical expertise meets strategic thinking meets human insight. Course Overview Being an effective communicator is an essential part of being an effective scientist, engineer, or technical professional. Effective, inclusive communication is the only way to share the results of your work, to collaborate, to innovate, and to meet your ethical obligations as a practicing professional. After taking this course, students will understand the importance of effective, inclusive communication in all aspects of professional practice and have a foundation of communication skills and habits. Course Topics • Purpose, audience, and communications decisions, • The writing process, • Document planning, outlining, organization, and format, • Reports, summaries, data graphics, presentation slides, • Intellectual property, research, and use of sources, • Oral communication and presentation skills, • Interpersonal communication, • Critiquing and feedback, • AI literacy and use of AI for communication, • Cross-cultural communication Two 75-minute class sessions per week (26 total class sessions) taught in person at the Tufts Medford campus. The ideal candidate will have professional experience in communications, leadership, and/or management in an engineering, technical, or related field. Previous college-level teaching experience at the undergraduate level is also preferred. The candidate will have a strong commitment to discussion-based and experiential learning. Candidates should submit their application, including a cover letter, resume, statement of teaching interests through Interfolio. Candidates are encouraged to demonstrate attention to diversity and inclusion as it relates to teaching, research, and scholarship throughout their application. Compensation: The compensation for this part-time Lecturer position in the Tufts Gordon Institute is $12,035 per 3 SHU course.

The Team and Leader Statement Executive Technology Services is an executive-level advisory service that delivers expert insight and guidance tailored to each member's context and most critical initiatives. EITL consists of 7 areas of expertise (domains) that cover several areas within IT: Applications, Data & Analytics, Enterprise Architecture, Infrastructure & Operations, Program & Portfolio Management, Security & Risk, Sourcing & Vendor Management. Gartner's Executive Partners specialize in one of the 7 domain areas and equip business leaders with indispensable insights, advice and tools to achieve their mission-critical priorities today and build the successful organizations of tomorrow. Our Associates enjoy a collaborative work environment, exceptional career development as well as unlimited growth potential. If you like working with a generous, supportive, high-performing team, Gartner is where you want to be. Job description • You will manage a portfolio of 25-30 clients, typically Chief Data Officers, from Fortune 100 organizations and large high-tech companies., • As their Executive Partner, you will be delivering value through regular briefings, workshops, roundtables, webinars and by attending relevant Gartner events, etc., • As someone with previous practitioner experience, you will use your knowledge and expertise, along with additional Gartner resources and research, to coach and mentor your clients on critical initiatives and obstacles for today and tomorrow specifically within the Data & Analytics space., • Collaboration is key. You will work closely with several internal Gartner teams to ensure value is delivered. These can include sales teams, analysts, client support managers, and your peers across other domains., • This role is a client-facing position that requires a high level of Executive presence and ability to build trust and deliver value., • You will be responsible for member retention and for contributing toward growth in the region through direct support of Gartner Sales in prospect cultivation, account plan development and value demonstration activities., • This is a predominantly work-from-home role, though there will be some client and internal travel involved. Essential must-have skills We'd love to talk to you if you have: • 15+ years' experience with a primary focus in an executive Data & Analytics leadership role such as, Chief Data Officer (CDO), Chief Analytics Officer (CAO), Chief Data Scientist, Data Scientist, VP/Sr. VP Business Intelligence and/or Analytics/Business Analytics within a Fortune 500 company., • Modern technical skills and subject matter expertise such as:, • CDO Focus: Advising on enterprise-wide data and information strategy, governance, control, policy development & data optimization, • Information Management Focus: Leadership perspective in Business Intelligence, Analytics, and Master Data Management approach in key industry verticals, • Data Science Focus: Artificial Intelligence, Generative AI, Large Language Models, Natural Language Processing (NLP), Machine Learning, Conceptual Modeling, Statistical Analysis, Internet of Things (IoT), AI/BOTS, • Experience in one or more of the following application disciplines is also desired: Agile/Bimodal IT, DevOps, Lean Development, Mobile app development, Cloud app deployment, Integration Strategy and API Management, App Maintenance Methods and Outsourcing, App Portfolio Management, • Minimum bachelor's degree required #LI-MB2 Who are we? At Gartner, Inc. (NYSE:IT), we guide the leaders who shape the world. Our mission relies on expert analysis and bold ideas to deliver actionable, objective business and technology insights, helping enterprise leaders and their teams succeed with their mission-critical priorities. Since our founding in 1979, we've grown to 21,000 associates globally who support ~14,000 client enterprises in ~90 countries and territories. We do important, interesting and substantive work that matters. That's why we hire associates with the intellectual curiosity, energy and drive to want to make a difference. The bar is unapologetically high. So is the impact you can have here. What makes Gartner a great place to work? Our vast, virtually untapped market potential offers limitless opportunities - opportunities that may not even exist right now - for you to grow professionally and flourish personally. How far you go is driven by your passion and performance. We hire remarkable people who collaborate and win as a team. Together, our singular, unifying goal is to deliver results for our clients. Our teams are inclusive and composed of individuals from different geographies, cultures, religions, ethnicities, races, genders, sexual orientations, abilities and generations. We invest in great leaders who bring out the best in you and the company, enabling us to multiply our impact and results. This is why, year after year, we are recognized worldwide as a great place to work. What do we offer? Gartner offers world-class benefits, highly competitive compensation and disproportionate rewards for top performers. In our hybrid work environment, we provide the flexibility and support for you to thrive - working virtually when it's productive to do so and getting together with colleagues in a vibrant community that is purposeful, engaging and inspiring. Ready to grow your career with Gartner? Join us. Gartner believes in fair and equitable pay. A reasonable estimate of the base salary range for this role is 160,000 USD - 194,000 USD. Please note that actual salaries may vary within the range, or be above or below the range, based on factors including, but not limited to, education, training, experience, professional achievement, business need, and location. In addition to base salary, employees will participate in either an annual bonus plan based on company and individual performance, or a role-based, uncapped sales incentive plan. Our talent acquisition team will provide the specific opportunity on our bonus or incentive programs to eligible candidates. We also offer market leading benefit programs including generous PTO, a 401k match up to $7,200 per year, the opportunity to purchase company stock at a discount, and more. The policy of Gartner is to provide equal employment opportunities to all applicants and employees without regard to race, color, creed, religion, sex, sexual orientation, gender identity, marital status, citizenship status, age, national origin, ancestry, disability, veteran status, or any other legally protected status and to seek to advance the principles of equal employment opportunity. Gartner is committed to being an Equal Opportunity Employer and offers opportunities to all job seekers, including job seekers with disabilities. If you are a qualified individual with a disability or a disabled veteran, you may request a reasonable accommodation if you are unable or limited in your ability to use or access the Company's career webpage as a result of your disability. You may request reasonable accommodations by calling Human Resources at +1 (203) 964-0096 or by sending an email to___. Job Requisition ID:97027 By submitting your information and application, you confirm that you have read and agree to the country or regional recruitment notice linked below applicable to your place of residence. Gartner Applicant Privacy Link: ___ For efficient navigation through the application, please only use the back button within the application, not the back arrow within your browser.

Job Locations US-MA-Newton ID 2026-18979 Job Function Research & Development Bruker is one of the world's leading analytical instrumentation companies enabling scientist to make breakthrough discoveries and develop new application that improve the quality of human life. Our high-performance products and high-value life science and diagnostic solutions are trusted by leading businesses, institutes, and scientists worldwide. Today, more than 11,000 employees at over 90 locations are working on this permanent challenge to make the world a better place. Bruker Spatial Genomics (BSG, a Bruker subsidiary) is focused on opening a new frontier in spatial 3D genomics and multiomic analyses. We are committed to the development of a novel technology platform allowing progress in genome-wide visualization of spatially resolved 3D chromosome and chromatin architecture in individual cells and cell populations in situ. We bring together the premier spatial omics approach, jebFISHTM, with leading-edge imaging, data acquisition and analysis capability. Our pioneering in situ technology enables examination of some of the most important questions in genomics and gene expression at the single cell and sub-cellular level. We aim to find the best talent in the field to join and contribute to this extraordinary endeavor, becoming a critical member of this groundbreaking opportunity. Bruker Spatial Genomics is looking for a Staff Scientist for their R&D team. The position and ideal candidate is described as follows: • The candidate will be a key contributor to optimization and development of advanced bioassays for determination of chromosome and chromatin architecture through the use of spatial omics approaches., • This is a unique multi-disciplinary position that will work closely with a variety of disciplines including scientists and engineers with molecular biology, general wet lab, or imaging experience. As part of our team, you will design and conduct cutting edge approaches and experiments to map spatial gene activity and expression and develop new technologies for multiomic integration. You will conceptualize and oversee technique invention, optimization, and transfer of the leading approach to in situ imaging of gene activity, localization, and expression in diverse tissue (FF and FFPE) and cell types., • The ideal candidate should have demonstrated wet lab experience working independently in a biophysics, chemistry, biochemistry, or molecular biology laboratory, have exceptional attention to detail, be creative, and be able to critically analyze data and communicate results to the team. This position must be able to independently make decisions on work direction., • They should be enthusiastic to work as part of a team in a fast-paced startup environment, and must bring a can-do attitude and sense of purpose to the job., • Support and spearhead the method development and optimization of novel molecular biology assay schemes for spatial omic applications including molecular barcoding, fluorophore marking, nucleic acid hybridization, amplification and sequencing techniques, and probe library preparation., • Support the optimization of probe chemistry and probe-based sequencing with spatial multi-omic profiling applications., • Help develop the optimization of sample preparation methods such as tissue/cell fixation and permeabilization in diverse tissue (FF and FFPE) and cell types., • Independently plan and execute experiments, accurately record details, provide in-depth analysis, and report results through documentation and presentations., • Assist/lead in the analysis of large and complex data sets, including developing routines for streamlined and automated data pipelines., • Prepare assay reagents and other components., • Work within multidisciplinary teams at all stages of product development., • Assist with research projects to profile spatial genomics. Collaborate with other team members on research studies., • Support and lead elements of the development, verification and validation of product related kits and reagents., • Analyze specimens on imaging instrumentation. Analyze research data and assist with data interpretation., • Interface directly with product development teams to transfer and optimize new technologies., • Prepare research reports and share findings with the team. Write protocols, develop procedures, and maintain accurate records., • Clearly communicate and present results; contribute data for making critical design decisions. Educational/Experience requirements: PhD in biophysics, chemical/biomolecular engineering, molecular biology, biochemistry, cell biology, or a related field and 5+ years of hands-on molecular biology experience in an industrial setting. • Proficient in standard molecular biology techniques such as sample preparation, nucleic acid amplification and purification (RNA/DNA), qPCR, and DNA sequencing or similar molecular biology techniques. Experience with applying microscopy to answer biological problems., • Knowledge of advanced fluorescence in situ hybridization (FISH) or other in situ fluorescence probed-based techniques. Understanding of basic absorption and emission spectroscopy., • Highly motivated with excellent attention to detail. Good communication (oral and written) and collaboration skills., • Experience in cell culture and tissue (FF and FFPE) preparation techniques., • Experience in troubleshooting and optimization of molecular biology assays including reagent formulation and workflow optimization., • Experience with experimental design and data analysis. Must be capable of performing complex multi-step experiments with detailed and diligent attention to technique and protocols with accurate record keeping., • Experience with multiplexed, multiomic imaging technologies in tissues and cells., • Experience in product development including product release., • Familiarity with basic statistical data and error analysis. Familiarity with single cell and/or spatial transcriptomics, fixation chemistry, Design of Experiments (DOE)., • Advanced fluorescence imaging techniques. Experience in microscopy image analysis., • Familiarity with different cell and tissue segmentation software and programs, • Experience with use and troubleshooting of automated equipment, preferably for imaging applications. At Bruker, base salary is part of our total compensation. The estimated base salary range for this full-time position is between $107,100 and $190,000 provides an opportunity to progress as you grow and develop within a role. The base salary for the role will depend on a several job-related factors, including, but not limited to education, training, experience, the geographic location of the successful candidate, skills, competencies, job-related knowledge and travel requirements for this position. Full-time employees may also be eligible for a performance-related incentive in addition to a full range of benefits including 401(k) with company match, an employee stock purchase plan, medical and dental plans, life insurance, short-term and long-term disability insurance, employee assistance program and paid time off including vacation, sick time and holidays, and more. Bruker is an equal-opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other legally protected characteristics. Certain positions at Bruker require compliance with export control laws and as a result, all interviewed candidates for all positions will be screened pre-interview to determine their eligibility in light of export control restrictions #LI-RD1

About the Job: The Scientist I, Assay Development supports the late-stage development and optimization of next generation sequencing (NGS) based assays in our clinical labs. Leveraging strong working knowledge of molecular biology, the incumbent in this position partners closely with other scientists and stakeholders cross functionally on high throughput automation and advancing NGS. The Scientist I prepares and analyzes human specimens, conducts laboratory experiments within guidelines and operates and maintains complex scientific equipment, such as high throughput liquid handlers. Additionally, the Scientist I evaluates and summarizes results, contributes to reports, presents data, and remains up-to-date with current publications relative to methods and techniques within relevant areas of research to leverage and integrate these. The Scientist I will work within the Assay Development group to help drive updates to Foundation Medicine’s comprehensive genomic profiling (CGP) assay. The main responsibilities of the Scientist I will be to contribute to the planning, execution and analysis of the laboratory experiments for the assessment and development of assay improvements. This role will have the unique opportunity to work cross-functionally in a product development environment to advance Foundation Medicine’s market-leading CGP tests focused at improving outcomes for cancer patients. Key Responsibilities: • Independently execute specialized and complex molecular biology techniques, including NGS workflows., • Collaborate with molecular biologists, computational scientists and regulatory scientists to support the feasibility and development of clinical oncology NGS diagnostic assays., • Design and conduct required feasibility and development and validation work, and help to draft standard operating protocols., • Operate complex laboratory equipment such as laboratory automation equipment., • Utilize data analysis interpretation and troubleshooting to identify methods to optimize assay features., • Author detailed, accurate, and accessible records of experimental data and protocols, plans and reports within the Quality Management System as needed., • Prepare reports and presentations to communicate results in group meetings., • Train and mentor research assistants and/or research associates on optimal processes and standard operating procedures., • Other duties as assigned. Qualifications: Basic Qualifications: • Bachelor’s Degree in Molecular Biology or a related life science fields and 6+ years of experience, • OR, • Master's Degree in Molecular Biology or a related life science field and 2+ years of experience, • OR, • PhD and 0 years of experience Preferred Qualifications:, • Advanced Degree (Master’s Degree+) in Molecular Biology or a related life science field, • Extensive experience with molecular biology techniques and an understanding of the practices and principals of NGS, including DNA-seq, NGS library preparation and target-enrichment, • Experience developing, implementing and supporting high complexity clinical assays, • Experience within the following regulated environments: Food and Drug Administration – Quality System Regulation, Clinical Laboratory Improvements Amendments, International Organization for Standardization and CAP, and in writing standard operating procedures, validation protocols and data reports within these environments, • A “results-oriented attitude”, demonstrated through a history of meeting individual and collaborative project deadlines, • Scientific thought process and understanding of assay parameters illustrating approaches to problem solving to inform assay troubleshooting and or optimization., • Good interpersonal skills that include excellence in written communication, oral communication, collaboration, and problem solving with other departments and colleagues, • Understanding of HIPAA and the importance of patient data privacy, • Commitment to reflect FMI’s values: Integrity, Courage, and Passion The expected salary range for this position based on the primary location of Boston is $102,000 - $124,000 per year. The salary range is commensurate with FMI’s compensation practice and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for FMI benefits.

About the Job The Senior Scientist, Assay Development helps lead the development, optimization, and deployment of NGS-based projects and initiatives on a cross-functional team that distill the latest advances in genomic science, technology, and clinical data into innovative, best-in-class clinical diagnostic tools or data products and enable oncologists to determine the best treatment throughout each patient’s journey with cancer. This position works closely with the Early Research, Technology, Quality, Regulatory, and Operations teams in development of next generation sequencing (NGS)-based assays and has the opportunity to mentor junior members of the team. This is a regulated position and additional information may be available from QA on the qualifications for this role pertaining to regulatory guidelines. Regular onsite work at a designated FMI location is an essential function of this role. The Senior Scientist, Assay Development role is an opportunity for an individual to contribute across functions and have a significant impact on FMI. The position is part of the Assay Development team, a sub-team of Product Development, and Research & Development at Foundation Medicine. This individual will help lead the development, optimization, and deployment of NGS-based projects and initiatives on a cross-functional team that distill the latest advances in genomic science, technology, and clinical data into innovative, best-in-class clinical diagnostic tools or data products and enable oncologists to determine the best treatment throughout each patient’s journey with cancer. They will work closely with our Early Research, Technology, Quality, Regulatory, and Operations teams in development of next generation sequencing (NGS)-based assays and will have the opportunity to mentor junior members of the team. This role requires strong working knowledge of molecular biology and NGS workflows, a collaborative approach to science, and strong communication and writing skills. Key Responsibilities • Meet regularly with a multidisciplinary team of Scientists, Engineers, Computational Biologists and other stakeholders to develop clinical NGS assays., • Develop and optimize the NGS platform and execute upon action steps identified in stakeholder meetings., • Guide, coach, direct, and develop direct reports, if applicable., • Add creative approaches in assay troubleshooting, optimization and problem solving., • Lead the development, optimization, and deployment of genomic methodologies including high throughput automation and NGS-based systems and workflows., • Lead, author, and execute development studies for novel diagnostic next generation sequencing assays., • Work collaboratively with the Early Research team to guide technology transfer into development., • Lead training and performance qualification testing during tech transfer between the development and operations teams., • Lead product documentation in fulfillment of Quality System Requirements design control, including CDx assay requirements, functional specifications, performance and study results, and data management., • Partner collaboratively with the Quality Assurance and Regulatory Teams to ensure that all procedural and submission documentation meets audit and accreditation standards., • Establish and validate performance parameters, quality control, and stability specifications for critical reagents., • Conduct investigations and analyses to troubleshoot and enhance existing methods, improving assay capabilities and technical robustness., • Author detailed, accurate, and accessible records of experimental data, present results at group meetings, to external collaborators., • Contribute scientific understanding to identify assay parameters and deliver this information throughout projects and initiatives described above., • Work across teams to assist in the setting up of a new R&D laboratory space., • Other duties as assigned. Qualifications: Basic Qualifications: • Bachelor’s Degree in Molecular Biology, Biochemistry, or Genetics and 11+ years of experience, • OR, • Master’s Degree and 7+ years of experience., • OR, • PhD and 5+ years of experience. Preferred Qualifications:, • PhD or equivalent in Molecular Biology, Biochemistry, or Genetics, • 8+ years of commercial science experience in Molecular Biology or Biochemistry, • Extensive experience with the practices and principles of Next Generation Sequencing (NGS), including DNA-sequencing and target-enrichment, • Extensive experience in standard molecular biology techniques and an understanding of the practices and principals of clinical specimen extractions (including FFPE, blood and tissue), • Strong experience in the development and/or implementation of high complexity clinical genomic assays within a regulated environment, • Experience writing standard operating procedures (SOPs), study protocols, and reports that fit within requirements of Food and Drug Administration – Quality System Requirements, Clinical Laboratory Improvement Amendments, College of American Pathologists, and International Organization for Standardization, • Experience with robotic liquid handlers, lab automation and instrumentation, • Demonstrated history of successfully managing multiple concurrent initiatives and maintaining one’s own workflow, • Demonstrated results orientation through successfully making traction on projects both working independently and collaboratively in a dynamic, fast paced team environment, • Demonstrated ability to clearly communicate scientific results in internal and external presentations and publications, • Ability to understand and analyze data generated on NGS platforms, • Strong interpersonal skills that include excellent collaboration and creative skills, • Excellent verbal and written communication skills including the ability to interpret and communicate complex scientific results to diverse and multi-disciplinary teams, • Strong problem-solving skills with other departments and colleagues, • Excellent organization and attention to detail, • Understanding of HIPAA and the importance of patient data privacy, • Commitment to reflect FMI's values: Integrity, Courage, and Passion The expected salary range for this position based on the primary location of Boston, MA is $140,000 - $165,000 per year. The salary range is commensurate with FMI’s compensation practice and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for FMI benefits. #LI-Onsite

The Position A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche. This role is in Analytical Data Science, a core function within Product Development Data Sciences (PDD) that provides strategic leadership and scientific rigor across Development at Roche. PDD Analytical Data Science teams are mobilized across the portfolio to generate data-driven insights, identify opportunities for scale, and implement impactful solutions. PDD Analytical Data Science is recognized as a leading hub for top industry talent, operating as an agile workforce to deliver regulatory commitments across the portfolio. We identify, influence, and adopt industry-leading digital and automation solutions, develop analytical approaches to support exploratory analyses, and align statistical programming practices across both early- and late-stage clinical development. The Opportunity The Data Scientist in the Data Science Acceleration (DSX) team is responsible for developing scalable tools, environments, and workflows that enable efficient, high-quality statistical computing across Product Development Data Sciences (PDD). This role focuses on creating and maintaining next-generation capabilities that support automation of programming workflows, generation of reusable coding macros, and advanced data visualization. Working closely with statistical programmers, biostatisticians, and clinical scientists, the Data Scientist translates scientific and operational needs into robust, modular, and user-friendly solutions that streamline evidence generation and support faster, more reliable decision-making across the development pipeline. • You provide strategic and technical leadership in the design and evolution of Roche's next-generation statistical computing platforms, ensuring they meet the future needs of PDD and the broader organization, • You anticipate emerging industry trends, technologies, and regulatory shifts, and translate them into forward-looking data science capabilities, frameworks, and standards, • You lead large-scale, cross-functional initiatives that redefine how clinical, operational, or real-world data are processed, visualized, and interpreted for decision-making, • You serve as a senior technical advisor to platform owners, programming and statistical leadership, and governance teams on complex topics involving infrastructure, automation, and scientific computing, • You guide technical vision, architectural decisions, and resource planning for high-impact tooling and infrastructure projects across DSX, • You resolve complex, system-level challenges across disciplines by applying deep scientific computing expertise and systems thinking, • You influence internal policy and development standards, and drive adoption of best practices that scale across teams, functions, and geographies, • You communicate complex technical ideas clearly to senior-level stakeholders and shape decisions on investment, tooling strategy, and portfolio priorities, • You foster a culture of technical excellence, collaboration, and innovation through mentorship, internal community building, and knowledge sharing Who you are: • You hold a PhD or Master's degree in Computer Science, Data Science, Statistics, Bioinformatics, Engineering, or a related quantitative field, • You have a minimum of 8 years of experience in data science, statistical computing, or platform development, with a demonstrated track record of impact at organizational or cross-functional levels, • You are a recognized expert in building and scaling scientific or statistical software systems, with deep understanding of clinical research environments and regulatory implications, • You bring expertise in multiple programming environments (e.g., Python, R) and development practices for reproducible, compliant, and high-performance computing, • You have demonstrated leadership of major programs or cross-functional initiatives with technical complexity and strategic significance, • You demonstrate capacity for independent thinking and ability to make decisions based upon sound principles, • You bring excellent strategic agility including problem-solving and critical thinking skills, and agility that extends beyond the technical domain, • You demonstrate respect for cultural differences when interacting with colleagues in the global workplace, • You have excellent verbal and written communication skills, including the ability to influence senior stakeholders and explain technical strategy with clarity and confidence, • You have proven experience leading global, cross-functional projects or workstreams, demonstrating effective coordination across time zones and diverse stakeholder groups Preferred Qualifications: • Experience shaping the architecture and long-term roadmap of enterprise-scale data science platforms or statistical computing environments, • Demonstrated ability to influence regulatory and quality frameworks in the context of digital and analytical tools, • Strategic understanding of healthcare data ecosystems, including real-world data, translational pipelines, and high-dimensional data integration, • Proven ability to drive tool adoption and cultural change through technical leadership, stakeholder engagement, and thoughtful design, • Engagement with external scientific or developer communities (e.g., open-source contributions, industry consortia, conference presentations), • Experience guiding investment and resource decisions for high-impact tooling or analytics initiatives, • Ability to synthesize organizational priorities and translate them into impactful, technically sound solutions at scale #PDDT #PDDBoston Relocation benefits are not available for this posting The expected salary range for this position based on the primary location of Boston is $189,400 - $351,800.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form ___.

Job DescriptionCompany Description The work we do at Eurofins Professional Scientific Services matters, and so do our employees. At Eurofins PSS, we put a focus on your professional growth. We provide our employees the ability to break into the biopharmaceutical industry and grow from the bottom up. We have the supportive teams and tools available to invest in you while also affording you work-life balance and a competitive benefits package. Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies. If you’re looking for a rewarding career, a place to call home, apply with us today! Job Description We are seeking a Biomolecule Production Scientist to support mammalian cell culture, transient transfection, and protein production workflows directly on a client site. This role is ideal for someone with a strong background in biochemistry or a related field who thrives in a collaborative, fast-paced laboratory environment. Key Responsibilities: • Maintain mammalian cell lines using aseptic technique and ensure consistent supply for twice-weekly transient transfection processes., • Perform transient transfections and purify antibodies/proteins using automated equipment under supervision., • Assist with molecular biology tasks such as cloning and plasmid preparation after training., • Accurately document experimental procedures and results in client-provided Electronic Lab Notebooks (ELNs)., • Analyze and summarize data upon training and contribute to troubleshooting and continuous improvement efforts.Qualifications, • B.S. in Biochemistry or a related field., • 0–2 years of relevant laboratory experience., • Proficiency in aseptic technique and mammalian cell culture., • Basic understanding of molecular biology techniques., • Strong communication skills and the ability to work effectively in a team environment., • Authorization to work in the United States indefinitely without restriction or sponsorship Additional Information What to Expect in the Hiring Process: • 10-15 Minute Phone Interview with Region Recruiter, • 45-60 Minute Virtual Interview with Manager and/or Group Leader What we offer: • Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options, • Life and disability insurance, • 401(k) with company match, • Paid vacation and holidays, • Yearly goal-based bonus & eligibility for merit-based increases

Job DescriptionSalary: About Aura: Aura Biosciences is a clinical-stage biotechnology company focused on developing precision therapies for solid tumors that aim to preserve organ function. Our lead candidate, bel-sar (AU-011), is currently in late-stage development for primary choroidal melanoma and in early-stage development in other ocular oncology indications and bladder cancer. Aura Biosciences is headquartered in Boston, MA. Our mission is to grow as an innovative global oncology company that positively transforms the lives of patients. For more information, visit aurabiosciences.com. Follow us on X (formerly Twitter) @AuraBiosciences and visit us on LinkedIn. Position Summary: Aura is seeking an experienced and highly collaborative Senior QC Scientist to support late-stage product development and drive Process Excellence initiatives. This role is critical to ensuring analytical readiness for commercial manufacturing through strong partnership with Contract Development and Manufacturing Organizations (CDMOs) and cross-functional internal teams. The ideal candidate is a seasoned analytical chemist with deep expertise in method validation, transfer, optimization, and troubleshooting in a cGMP-regulated pharmaceutical environment. This individual thrives in complex, fast-paced settings and brings both technical depth and the ability to influence and collaborate across organizations. Key Responsibilities Analytical Method Life Cycle Management & Validation • Lead analytical method activities to CDMOs, including transfer as appropriate, validation and authoring validation protocols and reports., • Manage and review work performed under method validation protocols, method performance, and any required third party activities., • Provide on-site technical readiness support and serve as SME during validation campaigns., • Troubleshoot and resolve technical challenges related to method life cycle management and validation in partnership with CDMO and internal stakeholders., • Monitor and trend analytical method performance in collaboration with Analytical Development (AD)., • Support quality systems activities, including change controls, deviation investigations, CAPAs, OOS investigations, and method improvements., • Perform statistical analyses to support method validation, qualification studies, and critical material qualification., • Author and review GMP documentation, including:, • Method transfer protocols and reports, as required, • Validation protocols and reports, • Test methods and best-practice documents, • Maintain comprehensive documentation of validation and transfer activities., • Partner closely with Analytical Development, MS&T, Quality Assurance, and external testing laboratories., • Lead training for new analytical methods at external labs and support QC analysts in execution, data analysis, and technical review. Subject matter expertise in analytical methods relevant to biologics and/or advanced therapeutics, including but not limited to: • qPCR, • ELISA, • Potency assays Qualifications • B.Sc., M.Sc., or Ph.D. in Analytical Chemistry, Pharmaceutical Sciences, or related scientific discipline, • Minimum of 10 years of pharmaceutical industry experience, with significant exposure to cGMP manufacturing and late-phase method validation, • Demonstrated expertise in:, • Analytical method validation and lifecycle management, • Process validation support, • Technology transfer and troubleshooting, • Proficiency in statistical software (e.g., JMP or equivalent), • Strong communication, negotiation, and stakeholder management skills, • Ability to operate independently, prioritize dynamically, and succeed in a fast-paced environment, • Willingness to travel to CDMO sites as needed Salary & Benefit Information: Salary Range: $150,000/yr - $215,000/yr (Placement within the listed range depends on many factors including, but not limited to: geographic location, degree, years of experience, and internal company equity) Health insurance with FULL premium coverage 401K with company match Employee Stock Purchase Program (ESPP) Competitive paid time off (PTO) Company-paid short & long-term disability insurance and life insurance

Job DescriptionSalary: $152,000 - $183,000 TheSenior Scientist, Research position is a key member of the Genomics Platform team and will be involved in bioinformatics analyses of genomics and multi-omics datasets to support our drug discovery and therapeutic development at Visterra. Reporting to the Executive Director of Research, this person will play a lead role in developing and applying advanced computational approaches to analyze and interpret genetics, genomics and multi-omics datasets to support our drug development decisions. We are seeking an experienced bioinformatician to develop and adapt data-driven approaches to analyze single cell multi-omics, spatial transcriptomics, genetics and other high-content datasets to aid target identification, disease characterization and mechanism-of-action studies to derive biological insights supporting drug candidate discovery and development. Responsibilities • Develop and implement advanced machine learning and computational strategies, including deep learning, graph-based methods, and probabilistic modeling, to extract insights genomics datasets, including single-cell, spatial and genetic modalities., • Collaborate with internal and external scientists and clinicians to drive insights from multi-omic data, supporting novel therapeutic development., • Develop new bioinformatics strategies efforts to address key target identification questions on underlying biological mechanisms of disease., • Leverage and extend best practices from genomics, statistics, and data science to process and analyze internal and public multi-omics data and derive biological insights that will impact program strategy., • Manage existing high-dimensional data resources and ingest new public and internal datasets for use by team members., • Clearly communicate complex data findings to colleagues and senior management., • Engage in research discussions, proactively suggesting innovative solutions to impact discovery and clinical programs., • Stay current with advancements in computational biology by reviewing literature, evaluating new technologies, and implementing relevant methodologies., • Present research findings at conferences and publish in scientific journals., • Participate in research team meetings, and proactively suggest new ways to impact programs from discovery through the clinic., • Maintain expertise in the field by staying current with relevant literature, proactively evaluate new technologies, and implement in-house where appropriate. Requirements • PhD. in Computational Biology, Bioinformatics, Computer Science, or a related field with 4+ years of experience, or a M.S. with 10 years of relevant experience., • Expertise in single-cell genomics (scRNA-seq), spatial transcriptomics, genetics or other large-scale multi-dimensional genomics analyses., • Deep experience implementing workflows to process high-throughput -omics data and performing downstream analyses that generate biological insights., • Proven track record of evaluating and using public biology databases, with an understanding of how to utilize large datasets to drive discovery and development, • Deep understanding in computational single cell toolsets such as Seurat, Scanpy, and other relevant methods., • Strong programming skills in Python and/or R for bioinformatics applications., • Familiarity with cloud computing services, such as AWS, is, • Excellent collaboration and interpersonal skills for multi-disciplinary teamwork., • Strong problem-solving abilities, analytical thinking, and intellectual curiosity., • Exceptional written and verbal communication skills, with the ability to present complex ideas clearly to diverse audiences., • Passion for developing computational technologies for biological research and translating findings into therapeutic applications in precision medicine and translational research. Management responsibilities: This position may include supervisory responsibilities. Travel: Possible travel to local and national conferences Company Visterra is a clinical stage biotechnology company committed to developing innovative antibody-based therapies for the treatment of patients with kidney, immune-mediated and other hard-to-treat diseases. Our proprietary technology platform enables the design and engineering of precision antibody-based product candidates that specifically bind to, and modulate, key disease targets. Applying this technology to disease targets that are not adequately addressed by traditional therapeutic approaches, we are developing a robust pipeline of novel therapies for patients with unmet needs. Visterras pipeline has multiple clinical-stage assets and one approved therapeutic, sibeprenlimab. As a member of the Otsuka family of companies, we are uniquely positioned as a small, dynamic, nimble and innovative organization where individuals and teams are empowered to make big impacts while benefiting from the support, strength, stability and long-term perspective of a 100-year-old global company. Visterra has approximately 105 employees and is located in Waltham, Massachusetts.