168 Best website Jobs in Memphis, Tennessee (May 2026)

Scientist or Postdoc Position and Wet Lab Lead Role

3 days ago

Memphis

Position Overview Join an excellent team of researchers dedicated to coming closer to the mission of St. Jude Children’s Research Hospital, that no child will die at the dawn of life. The QAI4Bio (Quantum AI for Biology) Lab led by Dr. Christoph Gorgulla within the Center of Excellence for Data-Driven Discovery in the Structural Biology Department of St. Jude seeks a skilled and highly motivated wet lab Scientist or Postdoc with experience in ligand discovery. Our research group is focused on developing state-of-the-art computational methods for ligand/drug discovery, using machine learning, high-performance/cloud computing, quantum chemistry and quantum computing. Our lab also includes a wet lab dedicated to experimentally verifying the computationally predicted results in real-world drug discovery projects. St. Jude was named #2 on Forbes America's Dream Employers 2026 (). As a (wet lab) Scientist or Postdoc, you will play a pivotal role in our team. This position is at the frontier of drug discovery, focusing to a large extend on the experimental validation of protein-ligand interactions. We will be targeting proteins associated with a range of areas, including epigenetic regulation, cancer, and other areas. You will work on producing high-quality proteins, designing and performing binding assays by biophysical methods (SPR, MST, ITC, BLI) or Fluorescence-based (i.e. FP, TR-FRET) methods, and optimizing workflows for ligand discovery. Depending on your skills, you might also work on structural studies (NMR, X-ray, cryo-EM, …) and use the state-of-the-art core facilities and centers dedicated to structural studies at St. Jude. In your role as lab manager you will be in charge of the day-to-day operations of the wet lab. Our lab is new, and you will be the first full-time team member in our wet lab. In addition, there is the “dry lab” where the computational/theoretical researchers will be located. In our lab, you will have the opportunity to lead collaborative projects, mentor junior scientists and students, and contribute to high-impact publications. Collaboration is at the heart of our work, and you will closely work with our computational and other wet-lab colleagues to validate and experimentally verify the predicted hit and lead compounds. By working together in a collaborative and intellectually stimulating environment, you will have the opportunity to contribute to multiple ligand/drug discovery projects and make a lasting impact on the lives of children and the world. Preferred starting date: Spring 2026 Job Responsibilities • Leading the wet lab experiments of our ligand/drug discovery projects with minimal to moderate supervision., • Protein Production: Express and purify target proteins of interest, predominantly using bacterial expression systems, and in cases needed insect, or mammalian systems. Ensure production meets quality standards for downstream structural and functional studies., • Binding Assays: Design and execute ligand-binding experiments, with a focus on biophysical assays and fluorescence-based assays, but also including cell-based assays. Optimize assay conditions for robust and reproducible results., • Wet Lab Leadership/Management: Manage day-to-day operations of the wet lab. Mentoring and training wet lab members, including postdocs, graduate students, and technicians. Oversee equipment maintenance and inventory of reagents., • Identify, process, organize, summarize, review, and report relevant data., • Interacting with computational team members (who will mostly identify the hit and lead compounds computationally)., • Manuscript preparation, submission, and the review process will be part of the responsibilities (under the supervision of the PI), ensuring that the lab’s findings are disseminated to the scientific community., • Actively collaborate with interdepartmental teams, fostering interdisciplinary approaches to solving complex scientific challenges., • Present research findings to internal and external audiences (e.g. conferences), contributing to the hospital’s mission of advancing pediatric research. About St. Jude St. Jude Children’s Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. The first and only National Cancer Institute (NCI)-designated Comprehensive Cancer Center devoted solely to children. Our 300 faculty work across the spectrum of basic, translational, clinical, and population science in a highly collaborative multidisciplinary environment that includes a Nobel laureate and members of the National Academy of Science and the National Academy of Medicine. St. Jude is ranked on Fortune Magazine’s “Best Workplaces in Health Care & Biopharma” and Glassdoor’s “Best Places to Work”. St. Jude is one of the best-funded research institutes in the US with an annual budget of over $2 billion per year (). What We Will Offer You Working at St. Jude is a remarkable experience in many ways, and you will be provided with many special perks. • Mission and Purpose: At St. Jude, working is more than just a job — it’s a calling. Each member of St. Jude is united by a shared purpose: finding cures and saving children. In addition to the meaningful work you will undertake, we offer a range of perks to enhance your experience., • Community and Belonging: St. Jude is like a warm family that welcomes you, to a large part because it is a Children’s hospital., • The Best of Both Worlds – Industry and Academia: St. Jude provides academic freedom in research and industrial efficiency and resources. We have access to world-class shared resources/facilities led by expert scientists, coupled with state-of-the-art technology and funding, accelerating research productivity., • Professional Growth: You will have access to opportunities to enhance your professional growth in terms of scientific skills, soft skills, and your career (St. Jude has well defined career path)., • Diversity: St. Jude is dedicated to fostering an inclusive and diverse scientific community, where everyone’s contributions are valued. More information is available here., • Competitive Compensation: Embark on your journey with a competitive salary (depending on experience) comprehensive benefits and generous relocation assistance, reflecting our commitment to recognize and invest in talent. Furthermore, in Memphis/Tennessee, there is no income tax., • Personalized Guidance: Dr. Gorgulla is committed to providing hands-on mentorship tailored to your needs and career aspirations. Whether you are refining scientific techniques or soft skills, you will have his full support., • Modern Buildings and Spaces: Our research group and wet lab is located in the newest building of the campus, the Inspiration 4 – Advanced Research Center, that cost of $400 million to construct. Top Employer About Memphis St. Jude is located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food, and culture. Living in Memphis provides several unique advantages, including: For a video with testimonials about how new St. Jude members experienced Memphis, see here: Compensation • Salary (depending on experience), • St. Jude offers a generous moving allowance to cover your costs related to your move to Memphis., • St. Jude provides temporary housing at reduced costs for several months after your move. Requirements • PhD in chemistry, biochemistry, biophysics or structural biology, drug discovery, or a related area. How to Apply If you are interested in the above position, please apply via LinkedIn and submit: • Cover letter (PDF format, "FirstName LastName - CĹ.pdf", sent via LinkedIn Message), • CV (PDF format, named as "FirstName LastName - CV.pdf", sent via LinkedIn Application System)

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