75 Best base Jobs in Leatherhead (June 2026)

Global Development Lead, Internal Medicine, Sr. Director (non-MD)

13 days ago

Tadworth

The Global Development Lead (GDL) represents Clinical on the Global Medicine Team and is the single clinical point of accountability for clinical development for assigned asset(s) in Internal Medicine, Research & Development, Pfizer. The individual will lead the cross-function Clinical Development Team including but not limited to clinical, clinical pharmacology, statistics, safety, commercial, patient access, and operations colleagues in the design, execution and interpretation of studies in support of worldwide regulatory submissions. The individual will be accountable for creating and gaining endorsement for the Clinical Development Plan and associated protocol design documents. The GDL is a key partner for other clinical and clinical operations colleagues through the lifecycle of all studies for the assigned asset(s). The GDL may also act as a key partner to external companies in support of Pfizer’s Partner of Choice model. The individual is expected to be an internal subject matter expert in their therapeutic area and in clinical drug development. They may assume responsibility for other clinical leadership opportunities in support of the Obesity portfolio. This may include responsibilities for trial design, execution and reporting of clinical trials for other late-stage assets in the portfolio. In addition, this leader: • May provide specialized monitoring support if required, • Lead efforts on regulatory submissions and contribute to submission deliverables including the SCE, SCS and clinical overview, • In support of assigned projects, provide input for target product profile(s), and regulatory activities including product labels, core data sheets, Investigator Brochures, Development Safety Update Reports, and Periodic Benefit-Risk Evaluation Reports, • Partners effectively with the Medicine Team Lead to negotiate tradeoffs, milestones and ensure delivery of the clinical program in line with agreed timelines and budget, • Responsible for comprehensive clinical development plan to secure approval and reimbursement globally (including China and Japan) along with creating the pediatric investigation plan / pediatric study plan and associated protocol design documents working closely with individual trial clinicians to ensure trial feasibility and optimized operational execution, • Provides product/program specific input for target product profile(s), • Willingness to bring innovative thinking and bold decision making across clinical development programs and individual studies, • Develops specific clinical development enabling strategies including digital / innovation and patient engagement approaches, • Partners with trial clinicians on governance reviews (incl Sci/Ops) for assigned clinical studies. Provides category clinical development strategy input and insights to trial clinicians for assigned clinical studies, • Provides therapy area/indication expertise in support of clinical review of clinical data – including CRF design, assistance in signal interpretation, contextualizing adverse events as required, • Provides specialized medical monitoring support for individual trial team, if required, • Key partner in trial-level statistical analysis plan, table-listings-figures, database release in partnership with statistics and programing, • Develops submission level deliverables (IAP, IARP and submission TLFs). Responsible for submission deliverables including SCE and SCS, • Support appropriate interpretation and communication of clinical trial data, • Review and approve submission level safety narrative plan, • Supports product label development and maintenance, • Engage key external stakeholders e.g., Ad boards, Steering Committees, DMC, Adjudication Committees, patients and patient advocates and other external stakeholders, to drive strategic insight generation to support clinical development strategy and PDD development, • Provides regulatory submission support (DSUR, PBRER) submission disclosure deliverables and product defense, • Ensures compliance with internal SOPs and external regulatory standards, • Review IIR proposals PhD/PharmD • Background in chronic weight management, endocrinology or internal medicine with experience in Phase 1-3 clinical development and translational medicine, • 8+ years of relevant experience and track record of success in academia and/or the biopharmaceutical industry in clinical research and development, • Extensive knowledge of clinical development, global and regional regulation, ICH/GCP, adverse event management, • Demonstrated clinical/medical, administrative, and project management capabilities, as well as effective verbal and written communication skills in relating to individuals both inside and outside the organization, • Demonstrated experience managing and training large teams in clinical development, • Demonstrated experience in designing and launching large teams preferred, • Candidate demonstrates a breadth of diverse leadership experiences and capabilities including the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact, • Medical / Scientific credibility/Excellence – Track record of achievement in pharmaceutical development, able to coordinate and execute clinical development or lifecycle strategy. Demonstrated understanding of the complexities and recent developments in the principal disease areas; confident discussing scientific / mechanistic aspects of drug development, also comfortable discussing commercial and regulatory issues, • Management experience – Able to work in a highly complex matrixed environment and able to influence cross-functional teams, • Leadership – Persuasive and effective leader of staff, • Influencing – Able to manage and motivate internal teams on clinical trials, • Conflict Management – Able to act as mentor / coach to others to improve conflict management skills; steps up to conflicts, seeing them as opportunities; reads situations quickly; can hammer out tough agreements and settle disputes equitably; prepared to take responsibility for a decision made and support this, even although it may be unpopular, • Team Building – Shares wins and success; fosters open dialogue; lets people finish and be responsible for their work; defines success in terms of the whole team; creates strong morale and spirit in his/her team; creates a feeling of belonging to the team, • Accountability – Take personal responsibility for results, pushing self and others to exceed goals and deliver results, • Change agile – Able to demonstrate perspective and poise in the face of uncertainty and effectively get things done amidst organizational change, • Candidate demonstrates a breadth of diverse leadership experiences and capabilities including the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact Up to 30% travel may be required. Relocation support available. This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits. Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future. Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. #J-18808-Ljbffr

Clinical Development Medical Director (Associate Director)

6 days ago

Tadworth

The Clinical Development Medical Director (Associate Director) is responsible for medical and scientific oversight, data integrity, and quality of clinical trials in Internal Medicine, with direct responsibility for clinical deliverables for one or more studies. They may also supervise and mentor others. • Provides medical monitoring on one or more clinical trials, • Provides timely, study-related medical information and guidance, e.g., on:, • Medical questions from investigator sites, • Medical issues in clinical trial data, • Medical findings in audits or inspections, • Contributes to medical assessments of Quality Events, • Conducts and documents periodic safety data review and ongoing clinical/medical data review, • Reviews Required Safety Text for the Informed Consent Document and significant medical changes in the Informed Consent Document, • Provides clinical support for one or more studies; may be accountable for program level clinical deliverables, • May provide input to the protocol design document; contributes to development of the protocol, including protocol amendments, Protocol Administrative Change Letters, and Dear Investigator Letters, • Supports the study team in internal protocol review governance submissions and interactions; supports the Global Development Lead in study and disease area strategy; may participate in protocol-related KOL and Health Authority interactions, • May develop Study Informed Consent Documents and responses to external stakeholder (e.g., Health Authority and Independent Ethics Committee) requests, • Provides clinical input to the development of the Statistical Analysis Plan and Tables, Listings, and Figures, • Provides clinical input to the development of the clinical data collection strategy, instruments, and data review plan, ensuring alignment with the protocol and SAP, optimized data collection principles, and clinical data review best practice; performs clinical data review; may present data to internal and external stakeholders; partners with site-facing colleagues in support of data issue resolution; ensures all clinical queries are appropriately addressed in support of database lock, • Provides clinical input to the development of the Safety Review Plan and Safety Narrative Plan; reviews safety data and may update clinical documents in response to emerging safety profile; tracks and reconciles Serious Adverse Events; participates in clinical safety data discussion during Safety Review Team meetings in collaboration with Medically Qualified Individual(s); reviews safety narratives, • Provides clinical input to the development of the Risk Management Plan; conducts clinical activities consistent with the approved Plan and partners with key stakeholders to develop and implement risk mitigations, • Supports establishment and management of External Data Monitoring Committees and Adjudication Committees, including chartering, contracting, provision and presentation of data, and documentation and dissemination of Committee recommendations, • Contributes to site selection criteria, provides clinical input to selection of sites, and may deliver protocol training to site-facing colleagues, • Participates in investigator meeting planning and may develop and deliver protocol training; may develop and deliver ongoing protocol training in response to e.g., protocol amendments, emerging data issues, and quality events, • May serve as a clinical point of contact with investigators and study team for questions relating to clinical aspects of the protocol; contributes to clinical response development, delivery, documentation, and curation (e.g., in FAQ), • May author protocol deviation sub-categories; ensures protocol deviations identified during clinical data review are reported; ensures all reported protocol deviations are appropriately managed and reconciled; may lead protocol deviation trends review, • Ensures TMF compliance for clinical documents, • Provides clinical input and review of the Clinical Study Report, • Provides clinical support to disclosure of safety and efficacy data and trial conclusions; may contribute to publications, • Provides clinical support to audits and inspections, including responding to and addressing audit and inspection findings, • May contribute to clinical sections of regulatory filings (e.g., Briefing Documents, Pediatric Investigational Plan, Investigator Brochure, IND/NDA Annual Reports, Periodic Safety Update Reports, responses to Health Authority requests), • Contributes to continuous improvement / process enhancement activities and innovative approaches to maximize effectiveness of clinical trial execution, • May supervise, mentor, or develop others, • As a Medically Qualified Individual (MQI), the successful candidate must have the following qualifications:, • Obtained a primary medical degree (e.g., MD, DO, MBBS, MBChB) from a recognized medical school/university and has some experience in biopharmaceutical industry in clinical research and development., • Been licensed by a licensing body/health authority to prescribe medicines independent of Supervision for at least 2 years post their intern/house officer/foundation period., • Cardiometabolic disease experience, e.g., obesity, diabetes, endocrinology, etc., • Have maintained registration/Medical License to practice and always been in good standing with their Medical Licensing Authority., • Clinical research experience in the biopharmaceutical industry in study design, start-up, conduct, and close-out, including regulatory submissions and inspections., • Scientific productivity via publications, posters, abstracts and/or presentations, • Knowledge of clinical development, global and regional regulation, and ICH/GCP, • Clinical and administrative capabilities; effective verbal and written communication skills, • Track record of achievement in pharmaceutical development; able to execute clinical development during design, start-up, conduct, close-out, and reporting, • Understands the complexities and recent developments in the principal disease areas; competent discussing scientific and regulatory aspects of drug development, • Able to set priorities to deliver milestones according to budgets and priorities, • Effective leader; able to mentor/coach, delegate to, and oversee others; able to develop others’ skills and move them toward autonomy, • Able to resolve conflicts equitably; fosters open dialogue; addresses conflicts; reads situations quickly; negotiates agreements; escalates issues when appropriate; takes responsibility for decisions, • Shares wins and success; defines success in terms of the whole team; develops strong team morale and spirit; creates a sense of belonging, • Takes personal responsibility for delivery of results, • Able to demonstrate perspective and poise in uncertainty and organizational change Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. Global travel may be required Relocation support available Work Location Assignment: Hybrid The annual base salary for this position ranges from $189,200.00 to $315,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future. Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical #J-18808-Ljbffr

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