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VolkerFitzpatrick offers a range and depth of civil engineering, infrastructure and building services. We contribute to vital parts of the nation's life through projects of strategic importance, while delivering those less visible, yet essential, works required by both private and public sectors. We build, renew, maintain highways, airports, railway infrastructure, and commercial, industrial and educational buildings. As a Project Quantity Surveyor, you'll play a key role in driving commercial success, maximising project value and cash flow while building strong relationships with clients, subcontractors, and suppliers. Acting as the commercial lead on site, you'll provide expert support on contractual and commercial matters, manage costs and project performance, identify risks and opportunities, and help ensure projects are delivered profitably, efficiently, and to the highest standards. About you • On site experience of 3+ years of maintenance contracts, • Experience of onsite measures, • NEC form of contract and subcontract conditions, • Other forms of contract desirable, • Managing others If your past experience doesn't match perfectly with every requirement of the job description, we still encourage you to apply. You may be just the right candidate for us. Why work with us? VolkerFitzpatrick is under the umbrella of VolkerWessels UK which is a multidisciplinary contractor that delivers innovative engineering solutions across the civil engineering and construction sectors including rail, highways, airport, marine, energy, water, and environmental infrastructure. By utilising the specialist skills of each business unit within VolkerWessels UK, VolkerFitzpatrick are able to ensure our staff provide unrivalled resources and expertise to our clients. We offer competitive rewards and benefits, recognising the value we place on our employees. We offer a range of benefits, including: • Competitive salary, • Competitive annual leave and an additional day off on your birthday, • Option to buy additional annual leave, • Private medical care, • Pension, • Life Assurance, • Cycle to Work scheme, • Shopping and restaurants vouchers, rewards, and discounts, • Training and development opportunities-comprehensive skills-based training, • Family friendly polices including enhanced maternity benefits, • Flexible working opportunities, • Employee Assistance programme, • Mental health, physical health, and financial support, • 24/7 Virtual GP service Fairness, inclusion and respect We believe in pushing boundaries in the pursuit of fairness, inclusion and respect. So, our teams can be comfortable that, whatever their background, VolkerWessels UK is a place where they can be themselves and thrive. If you need support with your application, please contact us at Additional Information Note for Recruitment Agencies: Our preference is to hire directly, and we will reach out to our Preferred Supplier List (PSL) agencies if this particular role qualifies for release. We kindly request that you refrain from sending speculative CVs. In the event of speculative CV submissions, no fees will be applicable, and we kindly ask that all inquiries to be directed VolkerWessels UK is committed to maintaining healthy, safe and productive working conditions for its entire staff and therefore a drugs & alcohol screening is mandatory for all. #LI-FS1 JBRP1_UKTJ

Job IntroductionAssociate Principal Scientist / Principal Scientist – Computational Chemistry (IDD)Location: Flexible UK remote working environmentPharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 29,000 employees worldwide across 28 locations in the UK, US, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services.We're proud of the impact we make and just last year, we supported 887 discovery projects, 1,100+ CMC programs, and 1,397 clinical trials across all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,300 global customers. To learn more, visit .The OpportunityWe are seeking an Associate Principal Scientist / Principal Scientist in Computational Chemistry to join our growing Integrated Drug Discovery team.This role offers the opportunity to play a leading scientific role across a broad portfolio of client drug discovery programmes, applying modern computational approaches to support compound design and optimisation from hit identification through candidate selection.Depending on experience and level, you may lead computational activities across multiple projects, act as a subject matter expert within multidisciplinary project teams, contribute to client interactions and help drive the development of new computational capabilities across the organisation.Working closely with medicinal chemists, biologists, DMPK scientists and project leaders, you will apply computational chemistry, molecular modelling, cheminformatics and AI-enabled approaches to solve challenging drug discovery problems and deliver impactful scientific outcomes.The RoleLead computational chemistry activities across integrated drug discovery projects from hit finding through lead optimisation and candidate selection.Design, evaluate and prioritise compounds using molecular modelling, structure-based drug design, virtual screening and cheminformatics approaches.Apply modern computational methodologies including AI/ML, molecular modelling and data-driven design strategies to support project progression.Collaborate closely with medicinal chemistry, biology and DMPK colleagues to guide compound design and decision making.Act as a key scientific contributor within multidisciplinary project teams.Present scientific recommendations and project updates to colleagues, collaborators and client partners.Contribute to the development and implementation of new computational workflows, tools and scientific capabilities.Mentor junior team members and contribute to knowledge sharing across the computational sciences group.Support scientific proposals, publications, conference presentations and business development activities.About YouPhD in Computational Chemistry, Molecular Modelling, Theoretical Chemistry or a related discipline.Significant experience in computational drug discovery within pharmaceutical, biotechnology or CRO environments.Strong track record supporting drug discovery programmes from hit identification through lead optimisation.Experience applying structure-based drug design, molecular modelling, cheminformatics and related computational approaches.Exposure to AI/ML methodologies within drug discovery is highly desirable.Strong understanding of medicinal chemistry and multidisciplinary drug discovery.Experience working effectively within cross-functional project teams.Excellent communication and scientific presentation skills.Key SkillsDeep understanding of computational chemistry and its application within drug discovery.Strong knowledge of medicinal chemistry, biology and DMPK integration.Ability to apply computational approaches to guide compound design and optimisation.Experience interpreting complex scientific data and translating findings into actionable recommendations.Ability to manage multiple scientific priorities in a collaborative environment.Strong stakeholder engagement and communication skills.Why Join Pharmaron?Work across a diverse portfolio of innovative drug discovery programmes.Apply cutting-edge computational chemistry, cheminformatics and AI-enabled technologies.Collaborate with world-class scientists across multiple disciplines.Flexible UK remote working environment.Opportunity to influence the progression of novel therapies from discovery towards the clinic. Salary Competitive Frequency Annual Job Reference ukpharmaron/TP/141/793 Contract Type Permanent Contract Closing Date No expiry date Job Category Scientific (CADD) Division Drug Discovery Location Hoddesdon, United Kingdom Posted on 6 November, 2026

Job IntroductionAssociate Principal Scientist, DMPKLocation: Hoddesdon, Hertfordshire, UKAbout the RolePharmaron is seeking an experienced Associate Principal Scientist, DMPK to join our Integrated Drug Discovery team in Hoddesdon.The Integrated Drug Discovery (IDD) Services group at Pharmaron is responsible for leading and delivering drug discovery projects for our client partners. The team comprises scientific expertise and strategic leadership across medicinal chemistry, CADD, biology, DMPK and translational science. Combined with Pharmaron’s global research capabilities we design and deliver integrated programmes from target identification and hit finding through to IND filing. Working closely with our partners we define strategy, coordinate execution across teams and with an AI enabled accelerated Design–Make–Test–Analyse cycles support the progression of projects and innovative medicines towards the clinic.This is an exciting opportunity for an experienced DMPK scientist to provide scientific leadership across a diverse portfolio of discovery programmes. You will apply your expertise in DMPK, ADME, pharmacokinetics and translational science to guide project strategy, interpret complex datasets and support informed decision-making.About PharmaronPharmaron is a premier R&D service company supporting the life sciences industry. Founded in 2004, Pharmaron has established a broad range of drug research and development capabilities spanning synthetic, medicinal and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry, metabolism, chemical and pharmaceutical development, and clinical development.Our Drug Discovery department in Hoddesdon provides scientific leadership to partners across the life sciences industry. Working in collaboration with Pharmaron’s global capabilities and resources, the multidisciplinary team delivers high-quality small-molecule preclinical candidates across a range of therapeutic areas and routes of administration.Our experienced scientists provide scientific leadership, strategy, molecule design and project oversight, helping our partners progress programmes towards candidate nomination and the clinic.The OpportunityYou will:Provide scientific leadership across integrated DMPK, ADME and PK activities.Develop fit-for-purpose study and screening strategies for small-molecule discovery programmes.Interpret and integrate in vitro ADME, in vivo PK and multidisciplinary project data.Conduct IVIVE, human PK and dose predictions, using state of the art techniques.Translate complex DMPK data into clear recommendations that support project decisions.Troubleshoot scientific and technical issues relating to DMPK and ADME studies.Prepare and present high-quality reports, data summaries and scientific recommendations.Act as a scientific point of contact for clients and multidisciplinary project teams.Coordinate DMPK activities across our global organisation to support timely and effective project delivery.About YouQualifications and ExperienceYou will have:A BSc, MSc, PhD or equivalent experience in pharmacology, pharmaceutical sciences or a related discipline.Significant experience supporting DMPK drug discovery or development programmes.Strong knowledge of in vitro ADME and in vivo PK principles, assays and how physicochemical properties impact these properties.Experience designing studies and interpreting complex PK and ADME datasets.Knowledge of IVIVE, human PK prediction and dose prediction methodologies.Familiarity with PBPK modelling approaches and relevant software is an advantage.Experience applying DMPK science to small-molecule discovery programmes With experience with other modalities an advantage.Experience working within multidisciplinary drug discovery teams.Previous pharmaceutical, biotechnology or CRO experience.Professional AttributesYou will be:Confident in providing scientific direction and technical recommendations.Able to communicate complex findings clearly to scientific teams and clients.Collaborative, client-focused and comfortable working across global teams.Organised and able to manage priorities across multiple projects.Proactive in identifying scientific challenges and developing practical solutions.Committed to scientific quality, continuous improvement and knowledge sharing.Why Join Pharmaron?Join a global, industry-leading drug discovery organisation.Contribute to drug discovery programmes from hit finding through to candidate nomination and IND.Collaborate with specialists across medicinal chemistry, biology, pharmacology, DMPK and translational science.Access Pharmaron’s global scientific capabilities and research platforms.Work in a state-of-the-art scientific environment at our Hoddesdon site.Develop your career within a collaborative and growing organisation.Apply NowIf you are an experienced DMPK scientist who is passionate about applying PK and ADME science to integrated drug discovery, we would love to hear from you.Join Pharmaron and help progress innovative medicines towards the clinic. Salary Competitive Frequency Annual Job Reference ukpharmaron/TP/142/795 Contract Type Permanent Contract Closing Date No expiry date Job Category Scientific (DMPK) Division Drug Discovery Location Hoddesdon, United Kingdom Posted on 9 November, 2026

Quantity Surveyor – Northern Home Counties Location: Welwyn Garden City Project / Office Based, with flexibility for occasional remote working Salary: £54,000 – £68,000 + Car or Car Allowance Benefits Office-based, with site visits, 1 day a week from home. 25 days holiday plus Bank Holidays Enhanced pension scheme Car or Car Allowance Supportive Tier 1 culture with long-term stability Genuine progression opportunities within a growing regional team Join a Leading Tier 1 Contractor A.D.S Construction Personnel Ltd are supporting a major Tier 1 contractor in the Northern Home Counties region to recruit an experienced Quantity Surveyor. This role has been created to strengthen the commercial team ahead of a significant increase in tenders and upcoming secured work across Education, Leisure and wider public sector frameworks. This is a people-focused, Investors in People Platinum environment with a strong forward order book, long-standing supply chain relationships and a culture built on trust, collaboration and Perfect Delivery. The Opportunity You'll join a respected commercial team within the London & Home Counties business, supporting both live projects and a growing pipeline of new work. The role suits a QS who is comfortable leading schemes up to £10m , or acting as a number two on larger projects. Experience in PCSA, running your own projects, and working within Tier 1/Tier 2 main contracting will be highly valued. Projects typically span Education, Leisure, Civic Buildings and public sector frameworks — with a strong emphasis on quality, customer service and repeat business. Key Responsibilities Provide accurate financial reporting to support commercial targets Manage subcontractor accounts, ensuring full contractual entitlements Build strong relationships with clients, consultants and supply chain partners Support site teams with contract requirements and commercial guidance Place and manage subcontract orders, ensuring timely payments and issue resolution Monitor subcontractor progress against programme Obtain competitive quotes and understand market trends Assist with CVRs, cost value reconciliations and cashflow forecasting Prepare applications for payment and ensure compliance with WIP and cash targets Monitor internal expenditure against budget Identify opportunities to maximise value and reduce cost Operate commercial systems effectively (including COINS) Support and coach junior commercial team members Manage variations, claims and additional payments Ensure full financial closure of projects in line with reporting timetables Ideal Background Experience delivering 2-stage projects Strong main contracting background Experience on Education or Leisure schemes between £10m–£30m Comfortable leading schemes up to £10m or supporting larger projects NEC4 or JCT experience BSc/HND in Quantity Surveying or similar, and/or RICS membership Strong understanding of construction techniques and commercial reporting Confident producing site records, cost reports and payment documentation Experience with COINS or similar commercial systems Why This Role Stands Out You'll be joining a Tier 1 contractor with national reach, a healthy forward order book and a culture that genuinely invests in its people. The team is inclusive, supportive and ambitious — with clear progression pathways and a strong reputation across Education, Leisure and public sector frameworks. If you're a Quantity Surveyor looking to progress your career in a stable, collaborative and development-focused environment, this role offers the platform to do exactly that. Apply today to discuss this opportunity in more detail. TPBN1_UKTJ

Sector: ConstructionReference: BBBH282033_1793893859Commercial Manager80,000 - 100,000LetchworthAre you a Commercial Manager or a Senior Quantity Surveyor looking for a role where you can take real ownership and shape how a growing main contractor operates? Do you want a long-term position with clear progression, including the opportunity to step into a director-level role as the business expands?On offer is a key position within a close-knit, family-run construction contractor, where you will take responsibility for the commercial function and play a central part in the company's next stage of growth. You will have the autonomy to improve processes, support the team, and make a visible impact on project delivery and profitability.The business delivers a mix of new build and refurbishment projects across sectors including commercial fit out, education, healthcare, industrial and heritage works. With ambitious plans to grow turnover over the next two years, they are looking to bring in an experienced commercial lead to support continued success.In this role you will be predominantly office-based in Letchworth, with regular site visits. You will lead and develop a small commercial team, manage contracts and commercial reporting, and support wider operational decision making across projects in London and beyond.This role would suit a Commercial Manager or Senior QS from a main contractor background, looking for long-term progression, genuine responsibility and the chance to help drive a growing business forward.The Role:Leading the commercial function for a growing main contractorManaging and supporting a small team including QS, junior QS and estimatorContract management, commercial reporting and supporting project deliveryThe Person:Commercial Manager / Senior Quantity Surveyor with main contractor experienceStrong contract knowledge (claims experience beneficial)Able to lead, develop people and take ownership within a small, close-knit businessReference Number: BBBH282033To apply for this role or to be considered for further roles, please click "Apply Now" or contact Reece Mitchell at Rise Technical Recruitment.Rise Technical Recruitment Ltd acts an employment agency for permanent roles and an employment business for temporary roles.The salary advertised is the bracket available for this position. The actual salary paid will be dependent on your level of experience, qualifications and skill set. We are an equal opportunities employer and welcome applications from all suitable candidates.Rise Technical Recruitment Ltd acts an employment agency for permanent roles and an employment business for temporary roles.The salary advertised is the bracket available for this position. The actual salary paid will be dependent on your level of experience, qualifications and skill set and will be decided by our client, the employer. Rise are not responsible or liable for any hiring decisions made by the end client.We are an equal opportunities company and welcome applications from all suitable candidates.

Main area Psychologists Early Intervention in Psychosis/First Episode Psychosis. Grade Band 7 Contract Permanent Hours 22.5 hours per week (Part time - 22.5 hours per week) Job ref 367-ACMS-101557-A Site Rosanne House Welwyn Garden City, AL8 6HG Town Welwyn Garden City Salary £51,657 - £58,785 per annum, pro rata (inclusive of 5% HCAS) Salary period Yearly Closing 22/11/2026 23:59 At Hertfordshire Partnership Foundation Trust we are looking for people to join us who share our values and those of the NHS. Before your application can be considered please take part on our online values questionnaire, which you can find below. When you have finished you will be sent a 'completion code' by email, which will be valid for 6 months and required to submit your application form. We have an exciting opportunity for a Clinical or Counselling Psychologist to join the PATH (Psychosis: Prevention, Assessment and Treatment in Hertfordshire) Service, a specialist Early Intervention in Psychosis team supporting people experiencing their first episode of psychosis. This is an excellent opportunity to become part of adynamic, supportive and forward-thinking multidisciplinary team dedicated to delivering high-quality, evidence-based care in line with NICE guidance. Alongside our commitment to clinical excellence, we are proud to be at the forefront of innovation and research. The service is actively involved in collaborations with the University of Oxford and King's College London, helping to implement novel psychological therapies, digital interventions and emerging technologies that enhance recovery outcomes for people experiencing psychosis. As a member of our team, you will have opportunities to contribute to service development, research and quality improvement initiatives, while working alongside highly skilled and experienced colleagues in a psychologically informed service. This post is suitable for newly qualified Band 7 Clinical or Counselling Psychologists who have keen interest in psychosis. As a specialist services, PATH provides comprehensive assessment and intervention for individuals experiencing psychosis. Psychological therapists play a central role within multidisciplinary team, contributing specialist expertise to formulation, treatment planning and service development. The successful applicant will: • Deliver evidence-based psychological interventions, including CBT, in line with NICE guidance., • Contribute to comprehensive assessments, including the use of psychometric measures where appropriate., • Support multidisciplinary colleagues through psychological formulation, consultation and collaborative care planning., • Play an active role in the continued development of psychologically informed practice across the service. We are committed to supporting the growth and development of our staff. The Trust offers excellent continuing professional development (CPD) opportunities and actively encourages clinicians to develop specialist interests that align with both service and professional goals. As part of your role you will be expected to engage with further training: CBT for Psychosis (CBTp) and Family Intervention for Psychosis (FiP), as well as other specialist courses as required. Hertfordshire Partnership University NHS Foundation Trustare one of just five mental health trusts to achieve an overall rating of ‘Outstanding’ from the Care Quality Commission Our family of over 4,000 members of staff provide health and social care for people with mental ill health, physical ill health and learning disabilities across Hertfordshire, Buckinghamshire, Essex and Norfolk, delivering these services within the community and several inpatient settings. Everything is underpinned by choice, independence and equality, with our Trust values embedded throughout: Welcoming. Kind. Positive. Respectful. Professional. About us - Hertfordshire NHS Partnership Trust Heard. Respected. Included. Together, we help people with mental ill-health, learning disabilities and autism to live life to the fullest. We work throughout Hertfordshire, Buckinghamshire, Norfolk... For detailed job description and person specification please refer to the JD/PS attached. It is anticipated that the post holder will work with people accessing service within East and South East Hertfordshire, but if necessary, it might be a requirement to work more widely within East and North PATH location to support delivery the service. • UK valid driving licence and access to a car, • Doctoral/Masters level training in clinical/counselling psychology, including specific models of psychopathology, clinical psychometrics, two or more distinct psychological therapies and lifespan developmental psychology, as accredited by the BPS and current registration with HCPC, • Professional qualification degree level, which should include knowledge and application of research methodology, • Additional specialist knowledge or training in psychological therapies including CBTp and Family Intervention, • Experience of specialist psychological assessment and treatment of clients across the full range of care settings, including outpatient, community, primary care and in patient settings, clinical experience working in adult mental health, • Experience of working with a wide variety of client groups, across the whole life span’s presenting problems that reflect the full range of clinical severity including maintaining a high degree of professionalism in the face of highly emotive and distressing problems, verbal abuse and the threat of physical abuse, • Knowledge of whole life span development and the impact on emotional, psychological and mental wellbeing, • Knowledge of the theory and practice of at least one evidence based psychological therapy (i.e. CBT, Family Intervention or CFT) relevant to the treatment of adults with complex problems and their families, • Doctoral level knowledge of research methodology, research design and complex, multivariate data analysis as practiced within the clinical fields of psychology, • Experience of multi-disciplinary team working and inter-agency collaboration, • Ability to provide consultation to other professional and non-professional groups, • Ability to teach and train others, using a variety of complex multi-media materials suitable for presentations within public, professional and academic settings, • Ability to take the appropriate action to address any issues or risks, • Awareness of Child and Adult Safeguarding Procedures, • Awareness of current NHS initiatives and Developments, • Knowledge of legislation and the national agenda in relation to Adult Mental Health, • Knowledge and awareness of specific clinical practices and issues relating to clients with mental health problems, • Ability to work autonomously as well as part of a team, • Experience of working in a community mental health setting, • Experience of service quality monitoring e.g. clinical audit, evaluative research, etc., • Experience of teaching, training and/or offering supervision, • Experience of service development/project management, • Ability to communicate orally and in writing, complex, highly technical and/or clinically sensitive information to clients, their families, carers and other professional colleagues both within and outside the NHS, • Ability to work and communicate therapeutically with clients and their families consistent with their level of understanding, culture, background and preferred ways of communicating, • Ability to work and communicate as a responsible participating member of a multi- disciplinary team and the ability to respect and value other members’ contributions and to encourage participation of all involved, • Ability to keep accurate and complete records of activities and communications consistent with legislation, policies and procedures., • Ability to alert line manager / team when direction, policies and strategies are adversely affecting users of services or the public, • Ability to time manage effectively and to work under pressure and to prioritise a clinical workload, • Positive problem solving approach, • Ability to critically evaluate and review developments made by others to determine if and how they could be applied within own area of work, • Ability to establish and maintain professional relationships and boundaries with clients from diverse backgrounds, • Ability to apply psychology in different cultural contexts, • Ability to recognise and report behaviour that undermines equality and diversity, • Car driver (unless you have a disability as defined by the Equality Act 2010 which prevents you from driving), • IT Skills; including the use of Microsoft Office and Outlook, entering data onto electronic patient records, • Ability to travel and work flexibly across different sites in Hertfordshire, • Ability to deliver complex methods of psychological assessment, intervention and management frequently requiring sustained and intense concentration, • Ability to recognise signs of stress and seek the appropriate support, • Ability to work with people whose behaviour is personally challenging, • Ability to comply with BPS/HCPC/BABCP professional standards and current developments in the field of mental health and well-being, • Ability to identify and employ mechanisms of clinical governance as appropriate to support and maintain clinical practice, • Flexible and positive approach to changing circumstances, • Ability to identify own developmental needs and takes responsibility for personal development, • Ability to act consistently with legislation, policies, procedures and other quality approaches and the ability to encourage and develop others to do so Please note, we do not charge fees for job applications, recruitment processes, sponsorship arrangements, or employment offers. Please see the Trust careers vacancy webpage and Trac as the only authorised routes for recruitment communications, applications and verification of job offers. You must have appropriate UK professional registration. This post is subject to the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975 (Amendment) (England and Wales) Order 2020 and it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service. #J-18808-Ljbffr

Scientist, AMS UK – Hoddesdon Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services. We’re proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit To continue our growth as a premier Contract Research Organisation, Pharmaron has opened a new Accelerator Mass Spectrometry (AMS) Laboratory at our Hoddesdon site. We are looking for a Scientist to join this new team. In this role, you will assist in the preparation and analysis of samples generated from clinical AMS-enabled studies, including mass balance, metabolite profiling and identification, and IVPK (absolute bioavailability). This is an exciting opportunity to gain hands‑on experience in a specialised, fast‑growing area of clinical analysis. • Vibrant and dynamic employment – we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and exciting!, • Opportunities to develop your skills and yourself – our rapid growth brings greater opportunities for you to learn and grow faster!, • A great team where we all support each other – enjoy your work – after all you spend about a third of your time here!, • Develop an understanding of analytical techniques used in AMS-enabled clinical studies through hands‑on training, • Perform duties of a Scientist, including: using and maintaining instrumentation, processing clinical samples for AMS analysis and contributing to data processing and QC checking, • With oversight from a scientific supervisor: prepare samples for analysis by AMS, prepare samples using the sample oxidizer and analyse samples by LSC, • Take responsibility for assigned instrumentation or processes as agreed with the Line Manager, • Contribute to the review and QC checking of study data packages and reports before QA submission, • Collaborate with the AMS team and wider Pharmaron stakeholders to ensure project milestones are achieved, • Communicate results and progress updates to key stakeholders, • Address findings from QA audits and inspections, • Participate in continuous improvement and efficiency initiatives with global AMS and metabolism teams, • Maintain and write SOPs, as required, • Work in a tidy, organised, and efficient manner, • Comply with Health & Safety, GCP, SOPs, and Study Plans, • Keep Personal Training File up to date, • Maintain confidentiality at all times, • Accurately record all work in the company timekeeping system, • PhD, MSc or BSc (Hons) in Chemistry, Biochemistry, Physics or related subject, • Experience working in a GxP laboratory setting, • Experience with sample processing and analytical techniques (e.g., HPLC), • Experience working with 14C-labelled materials, • Experience in drug discovery/development, • Experience with 14C-detection methods/instrumentation, • Effective written and verbal communication skills, including the ability to effectively present scientific findings to colleagues and clients, • Experience of coordinating / prioritizing multiple projects to meet internal and external timelines, • Effective problem solving and analysis skills, • Flexible mindset with the ability to take the initiative. Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. #J-18808-Ljbffr

We are seeking an experienced, dynamic and highly motivated Matron to lead our Ophthalmology services within the Surgery, Anaesthetics and Cancer Division. This is an exciting opportunity for a senior nurse with extensive ophthalmology experience to provide visible clinical, professional and operational leadership across our services. As Matron, you will champion high-quality patient care, lead service improvement, support workforce development and ensure delivery of safe, effective and responsive services. Working closely with clinical and operational leaders, you will play a key role in shaping the future of ophthalmology services, including the development of advanced clinical practice roles and innovative models of care. This role includes a clinical component, participation in the Senior Nurse out-of-hours rota and following a year focus on Ophthalmology expanding the portfolio to include Head and Neck services. This is a cross site role. Provisional date for interviews 19th November 2026. You will provide strong professional leadership to nursing teams, ensuring patients remain at the centre of all care delivery. Key responsibilities include: • Leading and developing ophthalmology nursing services., • Maintaining a visible clinical presence and supporting frontline care delivery., • Driving quality improvement, governance, patient safety and patient experience initiatives., • Managing and developing senior nursing staff through appraisal, coaching and workforce planning., • Leading responses to patient feedback, incidents and complaints to improve services., • Supporting education, training and professional development across the workforce., • Developing future workforce models, including Advanced Nurse Practitioner roles., • Managing resources effectively and contributing to budget planning and financial performance., • Working collaboratively with consultants, multidisciplinary teams, community partners and external stakeholders to deliver seamless patient pathways. With a new hospital planned for Watford, work underway to update theatres at St Albans City Hospital and plans for a neighbourhood healthcare centre in Hemel Hempstead, this is an exciting time to join us. We are building on the success of our award-winning virtual hospital and re-imagining models of care, working closely with partners and making the most of advances in digital healthcare. Staff wellbeing and development are a priority, as is the role of innovation in improving clinical care, outcomes and patient experience. Our vision is Excellent patient care, together and our values are to be empowered, compassionate, professional and inclusive. We offer a variety of flexible working options as we recognise the importance of a good work life balance. If you have a disability or long-term health condition and require support or guidance please contact . If you are a Service Leaver, Veteran, Military Reserve, Cadet Force Adult Volunteer, or partner/spouse of those serving please tick "Member of the Armed Forces Community" on the application form. The successful candidate will be accountable for clinical and non-clinical quality within Ophthalmology services and will work in partnership with the Clinical Lead, Head of Nursing and Divisional Senior Management Team to deliver operational and strategic objectives. You will provide professional leadership across the service, support implementation of the Trust Nursing Strategy, lead infection prevention initiatives, oversee workforce development and contribute to long-term service planning. The post holder will also participate in the Senior Nurse out-of-hours rota and work clinically to maintain visibility and credibility within the service. Core hours are typically Monday to Friday, with flexibility required to meet service needs, including participation in the out-of-hours senior nursing rota. • Current and relevant NMC registration., • First level registered nurse., • Post graduate qualification in Ophthalmology., • Evidence of continuous professional development., • Management experience including staff management., • Practice assessor or equivalent teaching qualification., • Evidence of master's level study., • Non Medical Prescriber Course., • Experience at Band 7 or equivalent, • Current knowledge of clinical practice in an acute setting., • Experience working in partnership with multi-disciplinary team., • Knowledge of current developments in nursing and the NHS., • Budget Management., • Lifelong learning, professional education and training., • Workforce planning, recruitment and retention., • Ability to operationalise strategies., • Significant experience managing a ward / unit., • Broad senior clinical and managerial experience relevant to the post., • Success in working collaboratively across professions and services., • Demonstrable success in managing change., • Experience with the introduction of evidence-based practice., • Project management., • Experience obtained in more than one clinical setting., • Research experience, audit experience. This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions. Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website. Applicants must have current UK professional registration. For further information please see NHS Careers website. Closing date: 10 November 2026 Reference number: 360-B-11994 Contract: Permanent Working pattern: Full-time, Flexible working #J-18808-Ljbffr

About Barhale Who are Barhale? Barhale is a business founded on family values, having been established by our Chairman, Dennis Curran, in 1980. We are one of the largest privately owned civil engineering and infrastructure specialists in the UK, with over 40 years of experience in providing design, civil engineering and maintenance services working across multiple sectors, including: Water Transport Built environment Energy We operate as a tier one partner for blue chip, regulated and private clients, working as part of large frameworks, joint ventures and alliances, as well as on individual standalone projects, developing long-term relationships based on delivering to the Barhale values which have been integral to our business since their inception in 1985. Our direct delivery model is at the core of everything we do, as we believe that people are our greatest asset. Therefore, we robustly source, train and retain all our own frontline delivery teams as well as management and support services. We employ over 1,200 employees nationwide. We possess a range of specialist skills to support our civil engineering and infrastructure activities, including: Tunnelling MEICA Temporary and permanent design Steel-fabrication Signs (design and fabrication) Health & safety equipment and products, including PPE Why join Barhale? As Gold Investors in People, we are committed to a high standard of people practices, creating an inclusive environment and ensuring cultural alignment to business strategy, ethos and philosophies. Job security, long-term secured work through various frameworks and large infrastructure schemes A broad range of civil engineering, mechanical and electrical schemes across some of the UK's largest infrastructure projects and clients Strong career progression as demonstrated by our track record in promoting from within, as we believe this is a key driver of our success Role Profile: Quantity Surveyor Reporting to: Senior Quantity Surveyor/Managing Quantity Surveyor Role Overview The Quantity Surveyor provides commercial support to project teams, maintaining accurate commercial information and ensuring compliance with contractual requirements and the Company's objectives. The role involves regular liaison with clients, client representatives and third parties on commercial matters, while actively identifying and realising commercial opportunities and mitigating business risk. Role Purpose To support the successful commercial delivery of projects through effective cost control, reporting, subcontract management and contractual compliance. The role ensures accurate forecasting, cash management and value recovery while contributing to the continuous improvement of commercial processes and practices. Key Accountabilities Commercial Management & Governance Ensure internal commercial processes are adhered to across the business unit Actively seek to improve commercial processes and procedures Maintain an understanding of JV / Alliance commercial processes where applicable and support their development Support compliance with contractual and commercial governance requirements Financial Performance Ensure robust, accurate and timely cost and value reporting at the project and business unit level Produce accurate cash flow reporting Carry out cost management and forecasting activities Update monthly CVRs, cost plans and commercial plans Demonstrate strong earned value and cost analysis capability Contract & Risk Management Ensure main contract terms and conditions are appropriate, with commercial risks identified Manage subcontract letting, negotiation and financial accounting Ensure supply chain engagement under correct contractual terms Prepare applications for payment Liaise with clients and third parties on variations, claims and additional payments Leadership & Capability Contribute to effective collaboration between commercial and operational site teams Share best practice and proactively advise site teams on cost management Work both independently and collaboratively within the commercial team Develop commercial acumen and technical capability Stakeholder Management Build and maintain effective client relationships Work closely with site management to forecast expenditure and cash recovery Liaise with subcontractors, suppliers and third parties on commercial matters Support operational teams in meeting commercial and delivery targets Key Interfaces Senior Quantity Surveyor / Commercial Manager Project Managers and Site Teams Clients and Client Representatives Subcontractors and Suppliers Commercial and Operational Teams Inter-company trading Proactively optimise inter-company trading wherever possible Collaborate effectively within the corporate group entities Success Measures (KPIs) Accuracy and timeliness of cost, value and cash reporting Effective cost control and forecasting Successful recovery of variations and additional payments Compliance with commercial processes and governance Quality of supply chain management and client relationships About you Essential Previous experience in the construction industry HND/degree (or equivalent) in Quantity Surveying Familiarity with ICE/NEC forms of contract and knowledge and understanding of Construction Law Previous experience in commercial management and procurement of subcontractors, including chairing regular meetings, measurement and control cycle, certificates, and accruals calculations. Ability to demonstrate a good knowledge of monthly reporting and earned value analysis. Have knowledge and experience in estimation and cost analysis. Excellent communication, numeric and computer literacy skills, proficient in Microsoft Office Organisation and time management skills, with the ability to work to tight deadlines Ability to work effectively in a team and delegate, but also able to work on own initiative Desirable Member of RICS or other relevant professional body, or working towards CSCS card Caring and investing in you Our values have been embedded at Barhale for over 40 years, and they are our guiding principles regarding how we care and invest in people. Our values are our commitment to being a people-centric company. As a Gold Investors in People company and a Sunday Times 100 Best Company to Work For, we are committed to investing in people. We are passionate about creating a working environment where people are supported throughout their careers, where people can enjoy security and be part of a company that cares about them. From the moment you join us, your well-being and career aspirations will be supported by. Competitive salary Company Pension Life Assurance Private Medical 25 days of annual leave in addition to 8 public bank holidays and loyalty days 8 hours volunteering Employee Assistance Programme to support your mental, physiological and financial wellbeing Flexible benefits via salary sacrifice Company car/green car scheme/car allowance/Van (dependent on position) Leadership & management training and coaching Regular line management engagement and appraisal to support your career progression Development supported by internal and externally delivered training Continuous service awards TPBN1_UKTJ

VolkerFitzpatrick offers a range and depth of civil engineering, infrastructure and building services. We contribute to vital parts of the nation’s life through projects of strategic importance, while delivering those less visible, yet essential, works required by both private and public sectors. We build, renew, maintain highways, airports, railway infrastructure, and commercial, industrial and educational buildings. We have an excellent opportunity for a Senior Planner in the Southern Region of our Building Division. Location – Based at our head office in Hoddesdon, with regular site visits and hybrid working available. A full UK driving licence is essential. As a Senior Planner in our Building Division, you’ll play a pivotal role in both the Pre-Construction and Construction Delivery teams, driving the success of projects ranging from £1M to £100M in Commercial, Education, Health & Life Sciences and Defence sectors Your strategic insight and technical know-how will ensure that every programme is robust, regularly monitored and updated to suit the needs of each project. What You’ll Be Doing In this dynamic and influential role, you’ll be at the heart of project planning, ensuring programmes are realistic, achievable, and aligned with client expectations. Your responsibilities will include: • Develop and produce fully logic linked and integrated ‘bid winning’ tender programmes comprising the design, procurement, construction, testing, commissioning and handover strategies that are compliant with tender requirements, design and chosen methodology without assistance., • Visiting sites regularlyto provide hands-on planning support and resolve challenges., • Monitoring progress and identifying risks early, ensuring proactive solutions are in place., • Providing expert planning adviceacross multiple projects, influencing outcomes and driving excellence., • Bringproven experience in construction planningwithin the main contracting sector., • Have a strong track record of working on tenders and live projectsvalued between£1M and £100M., • Are highly proficient inAsta Powerprojectandideally with experience with P6., • Possess an understanding ofJCT and NEC contract conditionsand their impact on planning., • Have a construction related qualification., • Are a confident communicator and strategic thinker, capable of influencing stakeholders at all levels. If your past experience doesn’t match perfectly with every requirement of the job description, we still encourage you to apply. You may be just the right candidate for us. VolkerFitzpatrick is under the umbrella of VolkerWessels UK which is a multidisciplinary contractor that delivers innovative engineering solutions across the civil engineering and construction sectors including rail, highways, airport, marine, energy, water, and environmental infrastructure. By utilising the specialist skills of each business unit within VolkerWessels UK, VolkerFitzpatrick are able to ensure our staff provide unrivalled resources and expertise to our clients. We offer competitive rewards and benefits, recognising the value we place on our employees. We offer a range of benefits, including: • Competitive salary, • Competitive annual leave and an additional day off on your birthday, • Option to buy additional annual leave, • Private medical care, • Pension, • Life Assurance, • Cycle to Work scheme, • Shopping and restaurants vouchers, rewards, and discounts, • Training and development opportunities-comprehensive skills-based training, • Family friendly polices including enhanced maternity benefits, • Flexible working opportunities, • Employee Assistance programme, • Mental health, physical health, and financial support, • 24/7 Virtual GP service We believe in pushing boundaries in the pursuit of fairness, inclusion and respect. So, our teams can be comfortable that, whatever their background, VolkerWessels UK is a place where they can be themselves and thrive. If you need support with your application, please contact us at Note for Recruitment Agencies: Our preference is to hire directly, and we will reach out to our Preferred Supplier List (PSL) agencies if this particular role qualifies for release. VolkerWessels UK is committed to maintaining healthy, safe and productive working conditions for its entire staff and therefore a drugs & alcohol screening is mandatory for all. #J-18808-Ljbffr

Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services. We’re proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,0 Pharmaron is seeking an experienced medicinal chemistry leader to drive the design and delivery of cutting-edge drug discovery programmes. You will lead end-to-end medicinal chemistry strategy, partnering with global, multidisciplinary teams to deliver high-quality candidates across diverse therapeutic areas. This is a high impact project facing role, ideal for scientific leader with a proven track record of advancing molecules through lead optimisation and a passion for innovation in medicinal chemistry and drug discovery. The Integrated Drug Discovery (IDD) Services group at Pharmaron is responsible for leading and delivering drug discovery projects for our client partners. The team comprises scientific expertise and strategic leadership across medicinal chemistry, CADD, biology, DMPK and translational science. Combined with Pharmaron’s global research capabilities we design and deliver integrated programmes from target identification and hit finding through to IND filing. Working closely with our partners we define strategy, coordinate execution across teams and with an AI enabled accelerated Design–Make–Test–Analyse cycle support the progression of projects and innovative medicines towards the clinic. • Lead and deliver medicinal chemistry strategies from hit identification to candidate selection, • Maintain a high degree of understanding of internal and external developments and approaches to medicinal chemistry design and optimisation, • Drive scientific excellence in compound design, ensuring clear hypotheses and robust data-led decision making, • Provide insightful medicinal chemistry critique across the IDD portfolio, • Work closely with CADD, in vitro biology, in vivo pharmacology and DMPK teams to design and advance compounds across discovery programmes, contributing scientific insight, data interpretation and chemistry leadership, • Provide leadership to global project teams, including close collaboration with China-based experimental teams, • Partner with clients and internal stakeholders to ensure efficient programme delivery, • Communicate programme strategy, progress and outcomes to senior leadership and external partners, • Support business development, proposal development and scientific positioning t, • Represent Pharmaron at International conferences, client meetings and industry events, • Contribute to IP strategy and patent drafting for client projects. You are a scientific leader with deep expertise in medicinal chemistry and experience operating in complex, fast-paced drug discovery environments. • PhD in Chemistry/Medicinal Chemistry (or equivalent experience), • 10+ years in drug discovery within a leading pharma, biotech or CRO, • Proven track record of delivering candidates into clinical development, • Experience of delivering ADC molecules through hit expansion and further optimisation in a discovery and preclinical environment, • Ideally you will also have experience managing external collaborations and client-facing projects, • Outstanding knowledge of medicinal chemistry, including the use of structural information, physicochemical properties and multiple parameter optimisation in compound design., • Knowledge of DMPK, toxicology and chemical conceptsrelevant to decision making and drug design., • Familiarity with modern synthetic chemistry and computational tools, • Strategic thinker with strong problem-solving and decision-making skills, • Collaborative leader, able to influence across functions, cultures and geographies, • Excellent communicator with a client-focused mindset, • Passion for innovation and continuous learning, • Results-driven with high attention to detail and execution Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. • Collaborate with a global network of scientific experts, • Contribute to transformational drug discovery programmes, • Opportunity to shape future capabilities and strategy Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 25,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. • Salary Competitive, • Frequency Annual, • Job Reference ukpharmaron/TP/79/770, • Contract Type Permanent Contract, • Closing Date No expiry date, • Job Category Scientific (Medicinal Chemistry) #J-18808-Ljbffr

We are seeking an experienced and motivated pharmacist to join our Pharmacy team on a full-time, fixed-term basis. Working within Older People's Services, you will provide specialist clinical pharmacy support, expert medicines optimisation advice, and leadership to multidisciplinary teams across the Trust. This role offers the opportunity to influence patient care, support service development, supervise and mentor pharmacy staff, and contribute to audit, research, and quality improvement initiatives. We are looking for a pharmacist with excellent clinical knowledge, strong communication skills, and a passion for delivering high-quality care for older patients. If you are looking to further develop your specialist practice within a supportive and forward-thinking pharmacy department, we would love to hear from you. • Assist the lead pharmacist in the delivery, development and evaluation of a high-quality clinical pharmacy service for Older People., • Provide expert advice on pharmaceutical matters, undertaking risk management and ensuring compliance with medicines legislation., • Participate in clinical audit and practice research., • Undertake training of pharmacy staff and other member of the multi-disciplinary team., • Actively deprescribe as a fully independent pharmacist prescriber and provide training in use of deprescribing tools to support reduction of polypharmacy in frail patients as per the Trust and departmental policies and procedures. With a new hospital planned for Watford, work underway to update theatres at St Albans City Hospital and plans for a neighbourhood healthcare centre in Hemel Hempstead, this is an exciting time to join us. We are building on the success of our award-winning virtual hospital and re-imagining models of care, working closely with partners and making the most of advances in digital healthcare. Staff wellbeing and development are a priority, as is the role of innovation in improving clinical care, outcomes and patient experience. Our vision is Excellent patient care, together and our values are to be empowered, compassionate, professional and inclusive. They capture an important balance across what we must all do as individuals and to support others. We offer a variety of flexible working options as we recognise the importance of a good work life balance. www.westhertshospitals.nhs.uk/flexibleworking If you have a disability or long-term health condition and require support or guidance please contact Date posted: 28 October 2026 Pay scheme: Agenda for change Band: Band 8a Salary: £59,798 to £67,020 a year inc HCA Contract: Fixed term Duration: 12 months Working pattern: Full-time, Flexible working Reference number: 360-C-11967 • MPharm (or equivalent overseas degree)., • Registered with General Pharmaceutical Council., • Certificate in Pharmacy Practice (or equivalent)., • MSc/Diploma in Pharmacy Practice (or equivalent)., • Registered Independent Non-Medical Prescriber., • Management Training., • Management Qualification., • Prescription Monitoring., • Computer and IT Literate., • Need for Confidentiality., • Well-developed therapeutic and clinical pharmacy knowledge in appropriate area., • Up to date knowledge of national pharmacy issues., • Critical appraisal skills., • Preparation of written reports and procedures., • NHS organisational structure., • Health and Safety., • Post qualification experience in hospital pharmacy including experience in the specialty in an acute setting., • Recent experience in providing clinical pharmacy services to Older People., • Experience of working as part of a multidisciplinary team., • Training Pre-reg Pharmacists and Junior Staff., • Audit/research and development., • Project management., • Managing Staff., • Clinical tutoring of postgraduate trainee pharmacists. This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions. Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website. From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants. Applicants must have current UK professional registration. For further information please see NHS Careers website. Employer name: West Hertfordshire Teaching Hospitals NHS Trust Address: Watford General Hospital, Watford, WD18 0HB, United Kingdom Employer's website: .uk Clinical Services Manager: Sital Sanghvi, , West Hertfordshire Teaching Hospitals NHS Trust's privacy notice. #J-18808-Ljbffr

Associate Principal Scientist, Medicinal Chemistry Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services. We’re proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit www.pharmaron.com. We have a new opportunity for an Associate Principal Scientist, Medicinal Chemistry to join the Integrated Drug Discovery (IDD) Services group at our Hoddesdon site. This role is responsible for providing medicinal chemistry expertise, leadership and project support for client projects. The Integrated Drug Discovery (IDD) Services group at Pharmaron is responsible for leading and delivering drug discovery projects for our client partners. The team comprises scientific expertise and strategic leadership across medicinal chemistry, CADD, biology, DMPK and translational science. Combined with Pharmaron’s global research capabilities we design and deliver integrated programmes from target identification and hit finding through to IND filing. Working closely with our partners we define strategy, coordinate execution across teams and with an AI enabled accelerated Design–Make–Test–Analyse cycle support the progression of projects and innovative medicines towards the clinic. • Demonstrate expertise in the core medicinal chemistry skills required to support drug discovery projects with a high degree of independence, including development of structure activity relationships, analysis of data and design of compounds to probe clear hypotheses towards the identification of clinical candidates., • Collaborate effectively with client and China-based experimental teams to enhance project delivery and efficiency, ensuring that scientific work is appropriately documented., • Use expertise to troubleshoot synthetic chemistry challenges, interpret results and plan additional experiments in collaboration with China-based synthetic chemists., • Provide scientific leadership and work with China-based experimental teams to advance drug discovery projects and the development of new capabilities., • Communicate project strategy, plans, results and achievements to internal stakeholders in a timely and open manner., • Keep abreast of scientific literature and the latest computational tools, contributing to the scientific and professional development of the IDD team., • Represent Pharmaron with the highest professional standards as required, e.g. in client interactions and at scientific conferences., • Support IP strategy development and patent application drafting for client projects., • PhD in Chemistry or Medicinal Chemistry, or equivalent industrial experience., • Significant experience in medicinal chemistry gained in academia, Pharma/Biotech and/or CROs., • Experience of hit to lead and lead optimisation phases in drug discovery projects and/or experience of modalities beyond traditional small molecules such as: ADCs or related targeted approaches; oral peptides; and oligonucleotide therapeutics is highly desirable, • Excellent knowledge of medicinal and synthetic organic chemistry, and working knowledge of DMPK/ADME assays and parameters., • Organises and directs own and supervises team efforts, where appropriate., • Demonstrable knowledge and/or experience of the drug discovery process for small molecules, from hit identification through to clinical candidate selection., • Able to critically review relevant scientific literature and assess patent literature, to ensure compounds are novel, and have freedom to operate., • Effective written and verbal communication skills, including the ability to effectively present scientific findings to colleagues and clients, • Strong decision-making and influencing skills, with the ability to work effectively across complex, global and matrix organisations, • Customer focused with the ability to build strategic relationships with internal and external stakeholders Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 25,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. • Salary Competitive, • Frequency Annual, • Job Reference ukpharmaron/TP/79/766, • Contract Type Permanent Contract, • Closing Date No expiry date, • Job Category Scientific (Medicinal Chemistry) #J-18808-Ljbffr

HV Commissioning Engineer 9 month contract £600/day - Outside IR35 Hertfordshire - site-based • Carry out testing and commissioning of HV electrical equipment, • Support commissioning activities across substations and distribution networks, • Test switchgear, protection systems and associated electrical plant, • Complete commissioning procedures, test sheets and technical documentation, • Identify faults and resolve commissioning issues, • Ensure work complies with approved procedures and safety requirements, • Liaise with project managers, engineers and site teams, • Support energisation, handover and completion activities, • Proven HV testing and commissioning experience, • Experience across 11kV, 33kV and/or 132kV networks, • Knowledge of substation equipment and protection systems, • Ability to interpret electrical drawings and technical documentation, • Experience completing commissioning records and test reports, • Strong understanding of electrical safety and safe systems of work, • Relevant HV authorisations and electrical safety qualifications, • UKPN network experience, • Protection and control testing experience, • Experience commissioning newly installed substation equipment #J-18808-Ljbffr

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. Within Pharma Research & Early Development (pRED), our Ophthalmology teams are redefining how precision medicine can transform the detection and treatment of complex retinal diseases. This is a rare opportunity to build a new function from the ground up — establishing an Ophthalmology Precision Medicine group at our Welwyn site that brings together biomarker science, advanced imaging, clinical expertise, and artificial intelligence. You will have the platform, pipeline, and resources to shape something truly new in one of the most dynamic areas of ophthalmic research. • Build a new Ophthalmology Precision Medicine function from the ground up — defining the vision, structure, and scientific direction for a group that integrates biomarkers, advanced imaging, clinical science, and AI across the pRED Ophthalmology portfolio, • Lead a cross-functional expert team spanning translational medicine, imaging, clinical development, data science, and biomarker disciplines — ensuring precision medicine is at the heart of our Ophthalmology strategy, • Bridge laboratory science and clinical practice by steering the generation of robust fluid- and imaging biomarker strategies that enable project and disease area decisions, • Advance innovation in imaging science by directing cutting-edge ophthalmic imaging approaches including OCT, OCT-A, and FA to inform future clinical practice and therapeutic development, • Enable translational insights through AI and data by integrating preclinical and clinical datasets using classical and next-generation analytical approaches, • Influence portfolio strategy across multiple retinal diseases including neovascular AMD, diabetic macular edema, geographic atrophy, and intermediate AMD — driving the direction and future of clinical development and research, • Represent Roche externally through strong partnerships with scientific experts, investigators, and the broader ophthalmology community — remaining at the forefront of innovation, • You are a board‑certified ophthalmologist (MD or MD/PhD) with deep expertise in ophthalmology, translational medicine, or biomedical sciences, • You are a recognised expert in the retina space, with a strong scientific publication record and standing as a key opinion leader in your field, • You have deep knowledge of ophthalmic imaging technologies (OCT, OCT‑A, FA) and experience with imaging analysis or Reading Centre environments, • You are experienced in integrating preclinical and clinical data to support proof of biology, efficacy, and safety strategies, with some exposure to clinical trials, • You are a collaborative scientific leader who thrives in matrix environments, energised by innovation and the opportunity to build something new, • Experience applying AI or machine learning to ophthalmic imaging analysis or clinical data interpretation, • Prior experience in pharmaceutical drug development programmes for retinal diseases, • Flexible working arrangements may be available for exceptional candidates who wish to maintain some clinical activity alongside this role If building a world‑class precision medicine function and shaping the future of ophthalmic therapy development is the kind of challenge that excites you — apply now and help us bring transformative medicines to patients faster. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life‑changing healthcare solutions that make a global impact. Let’s build a healthier future, together. The statements herein are intended to describe the general nature and level of work being performed by employees, and are not to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. Furthermore, they do not establish a contract for employment and are subject to change at the discretion of Roche Products Ltd. At Roche Products we believe diversity drives innovation and we are committed to building a diverse and flexible working environment. All qualified applicants will receive consideration for employment without regard to race, religion or belief, sex, gender reassignment, sexual orientation, marriage and civil partnership, pregnancy and maternity, disability or age. We recognise the importance of flexible working and will review all applicants’ requests with care. At Roche difference is valued and we are proud to be an equal opportunity employer where you are encouraged to bring your whole self to work. #J-18808-Ljbffr

We are looking for an experienced VAT/US Sales Tax professional to join the Tax team on a six-month fixed-term contract. This is a project-focused role supporting key VAT/US Sales Tax transformation initiatives across EMEA and the US, with particular emphasis on the SAP S/4HANA implementation and strengthening VAT processes and controls across our EMEA entities. You will bring strong technical VAT/US Sales Tax expertise together with practical experience of VAT/Sales Tax processes, ERP systems and tax controls. They will work closely with the EMEA and US Tax teams, Finance, IT and other stakeholders to ensure that VAT/Sales Tax requirements are appropriately designed, tested and implemented within SAP S/4HANA. The role will also undertake a programme of VAT health checks across Illumina's EMEA entities, identifying compliance risks, process gaps and opportunities to simplify, standardise and improve the efficiency of VAT processes., SAP S/4HANA implementation and UAT • Support the EMEA and US Tax teams with VAT/US Sales Tax-related User Acceptance Testing (UAT) for the SAP S/4HANA implementation., • Develop, review and execute VAT/US Sales Tax test scenarios covering key transaction flows and VAT/US Sales Tax requirements., • Validate VAT/US Sales Tax determination, tax codes and VAT treatment across relevant purchase and sales transactions., • Identify, document and help resolve VAT/US Sales Tax-related system defects and configuration issues arising through UAT., • Work with Tax, Finance, IT and project stakeholders to ensure VAT/US Sales Tax requirements are correctly reflected within the new system., • Support testing of end-to-end VAT/US Sales Tax processes, including relevant VAT/Sales Tax reporting and compliance outputs., • Help ensure appropriate documentation and controls are in place ahead of implementation., • Undertake structured VAT health checks across Illumina's EMEA entities., • Review key VAT processes, transaction flows, VAT determination and compliance controls., • Identify potential VAT risks, control weaknesses and areas requiring remediation., • Assess whether existing VAT processes can be simplified, standardised or automated., • Develop practical recommendations and work with the EMEA Tax team and relevant stakeholders to implement improvements., • Identify opportunities to improve the efficiency and consistency of VAT compliance processes across the region., • Document findings, actions and recommendations to provide a clear audit trail and support ongoing VAT governance., • Support the wider Tax team in developing more efficient and scalable VAT processes., • Identify opportunities to reduce manual intervention and improve the use of systems and data within VAT compliance and reporting., • Help standardise VAT processes and controls across EMEA where appropriate., • Provide technical VAT input into wider finance and tax transformation initiatives as required. Significant practical experience in VAT/US Sales Tax, ideally gained within a multinational organisation, Big Four firm or other complex international environment. • Strong knowledge of EU, UK VAT and US Sales Tax principles and cross-border transactions., • Experience of reviewing VAT processes and controls and conducting VAT health checks or similar risk reviews., • Experience working with ERP systems, ideally SAP and preferably SAP S/4HANA., • Previous experience of system implementation, VAT/US Sales Tax configuration testing or UAT would be highly desirable., • Strong understanding of VAT/US Sales Tax determination and typical order-to-cash and procure-to-pay transaction flows., • Ability to translate technical VAT/US Sales Tax requirements into practical system and process requirements., • Strong analytical and problem-solving skills., • Ability to work independently and manage multiple workstreams within a defined project timetable., • Strong communication skills and the ability to work effectively with Tax, Finance, IT and other business stakeholders across different jurisdictions., • Work with internal systems and departments to ensure accurate documentation of tax positions, • Assist with VAT and employment tax compliance as needed At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. The estimated base salary range for the Senior Tax Analyst role based in United Kingdom is GBP 63,800 - 95,600.The range reflects long-term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. This salary range applies to the primary posting location listed above. Should the level or location of the role change during the hiring process, the applicable base pay range will be updated accordingly. Compensation ranges for other locations will differ to reflect local market competitiveness and will be shared with candidates if applicable during the recruitment process. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a thoughtfully designed benefits package that supports your wellbeing, flexibility, and life beyond work-combining globally differentiated offerings with locally tailored programs. This includes support during important life moments, flexible time off, opportunities to give back, and a weeklong company-wide summer shutdown. In the UK, we also offer flexible benefits, a company contribution of 10% into your pension, and private medical insurance, alongside additional benefits to support you and your family. We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina #J-18808-Ljbffr

We are seeking an experienced Assistant Quantity Surveyor with a strong construction background and relevant industry qualifications to join our team delivering new modular build projects. The role requires excellent commercial awareness, strong reporting skills and the ability to lead procurement activities across multiple work packages. • Manage all commercial aspects of maintenance projects, including cost planning, forecasting, and financial reporting., • Produce and maintain Cost Value Reconciliations (CVRs), ensuring accuracy and timely submission., • Lead the procurement process, including tendering, bid analysis, negotiation and subcontract appointment., • Prepare and analyse Bills of Quantities, schedules and tender documentation., • Oversee commercial management of Mod Pods, SIP panels, groundworks packages and associated modular build elements., • Manage subcontractor accounts including payments, variations, claims and final accounts., • Support valuation processes, applications for payment, and contractual correspondence., • Work closely with site teams in Basildon and the commercial/technical teams based in Southwark., • Ensure compliance with contract conditions, company procedure and relevant legislation., • Monitor project costs versus budget, ensuring value engineering opportunities are identified and implemented., • Contribute to risk management and maintain accurate commercial records throughout the project lifecycle., • Strong background in construction with relevant Quantity Surveying qualifications (HNC/HND, BSc, or equivalent)., • Proven experience working on modular build projects or modern methods of construction (MMC)., • Experience working with CVRs, Bills of Quantities, procurement and subcontract management., • Understanding of Mod Pods, SIP Panels and groundworks packages., • Strong numerical, analytical and communication skills., • Ability to work across site (Basildon) and office environments, • Excellent commercial judgement and attention to detail., • Competent in cost reporting, contract administration and project forecasting. #J-18808-Ljbffr

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. Within Pharma Research & Early Development (pRED), our Ophthalmology teams are redefining how precision medicine can transform the detection and treatment of complex retinal diseases. This is a rare opportunity to build a new function from the ground up - establishing an Ophthalmology Precision Medicine group at our Welwyn site that brings together biomarker science, advanced imaging, clinical expertise, and artificial intelligence. You will have the platform, pipeline, and resources to shape something truly new in one of the most dynamic areas of ophthalmic research. • Build a new Ophthalmology Precision Medicine function from the ground up - defining the vision, structure, and scientific direction for a group that integrates biomarkers, advanced imaging, clinical science, and AI across the pRED Ophthalmology portfolio., • Lead a cross-functional expert team spanning translational medicine, imaging, clinical development, data science, and biomarker disciplines - ensuring precision medicine is at the heart of our Ophthalmology strategy., • Bridge laboratory science and clinical practice by steering the generation of robust fluid- and imaging biomarker strategies that enable project and disease area decisions., • Advance innovation in imaging science by directing cutting-edge ophthalmic imaging approaches including OCT, OCT-A, and FA to inform future clinical practice and therapeutic development., • Enable translational insights through AI and data by integrating preclinical and clinical datasets using classical and next-generation analytical approaches., • Influence portfolio strategy across multiple retinal diseases including neovascular AMD, diabetic macular edema, geographic atrophy, and intermediate AMD - driving the direction and future of clinical development and research., • Represent Roche externally through strong partnerships with scientific experts, investigators, and the broader ophthalmology community - remaining at the forefront of innovation., • You are a board-certified ophthalmologist (MD or MD/PhD) with deep expertise in ophthalmology, translational medicine, or biomedical sciences., • You are a recognised expert in the retina space, with a strong scientific publication record and standing as a key opinion leader in your field., • You have deep knowledge of ophthalmic imaging technologies (OCT, OCT-A, FA) and experience with imaging analysis or Reading Centre environments., • You are experienced in integrating preclinical and clinical data to support proof of biology, efficacy, and safety strategies, with some exposure to clinical trials., • You are a collaborative scientific leader who thrives in matrix environments, energised by innovation and the opportunity to build something new., • Experience applying AI or machine learning to ophthalmic imaging analysis or clinical data interpretation., • Prior experience in pharmaceutical drug development programmes for retinal diseases., • Flexible working arrangements may be available for exceptional candidates who wish to maintain some clinical activity alongside this role. A healthier future drives us to innovate. Together, more than 100,000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let's build a healthier future, together. The statements herein are intended to describe the general nature and level of work being performed by employees, and are not to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. Furthermore, they do not establish a contract for employment and are subject to change at the discretion of Roche Products Ltd. At Roche Products we believe diversity drives innovation and we are committed to building a diverse and flexible working environment. All qualified applicants will receive consideration for employment without regard to race, religion or belief, sex, gender reassignment, sexual orientation, marriage and civil partnership, pregnancy and maternity, disability or age. We recognise the importance of flexible working and will review all applicants' requests with care. At Roche difference is valued and we are proud to be an equal opportunity employer where you are encouraged to bring your whole self to work. #J-18808-Ljbffr

Location: Hoddesdon, Hertfordshire Department: Pharmaron Drug Discovery Level: Principal Scientist Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the UK, US, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services. We're proud of the impact we make and just last year, we supported 887 discovery projects, 1,100+ CMC programs, and 1,397 clinical trials across all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,300 global customers. To learn more, visit We are seeking an experienced PK/PD Principal Scientist to provide scientific leadership in pharmacokinetic/pharmacodynamic modelling, simulation and quantitative pharmacology across our global drug discovery and development organisation. This is a highly influential opportunity for an established modelling scientist who combines deep technical expertise with the ability to shape scientific strategy, lead complex client programmes and develop organisational capability. You will lead the design and delivery of PK/PD modelling strategies spanning discovery through clinical development. By integrating pharmacokinetic, pharmacodynamic, biomarker, efficacy and safety data, you will provide the quantitative insight needed to support candidate selection, translation to humans, dose and regimen selection, and wider clinical development decisions. Working across global DMPK, discovery and development teams, you will help strengthen our integrated quantitative pharmacology offering while enhancing Pharmaron’s scientific reputation with clients and the wider scientific community. • Provide scientific leadership for the design, execution, interpretation and communication of PK/PD modelling and simulation programmes., • Work with the global DMPK leadership team to define and implement our PK/PD modelling and quantitative pharmacology strategy., • Develop fit-for-purpose models integrating PK data with pharmacology, biomarkers, efficacy and safety endpoints., • Quantify exposure-response relationships and translate modelling results into clear, evidence-based project recommendations., • Apply translational PK/PD approaches to support:, • Candidate selection, • Proof-of-concept strategies, • Prediction of human efficacious doses, • Dose and regimen selection, • Therapeutic index assessment, • Clinical study design, • Provide scientific leadership across compartmental PK, exposure-response, direct and indirect response, mechanistic and semi-mechanistic PK/PD, disease progression and population modelling approaches., • Lead client-facing programmes, including modelling strategy development, scientific discussions, proposals, scopes of work, reports and presentations., • Provide senior scientific input to multidisciplinary project teams and influence decisions through clear quantitative interpretation of preclinical and clinical data., • Mentor, train and provide technical guidance to scientists working in PK/PD modelling and quantitative pharmacology., • Establish appropriate modelling software, workflows, analytical standards, documentation and model-quality practices., • Identify opportunities for scientific innovation, service development and the continued growth of our global PK/PD capabilities., • Build our external scientific profile through publications, conference presentations, webinars and collaboration with Business Development and Marketing., • A BSc or higher degree in a relevant quantitative or scientific discipline, such as mathematics, engineering, bioscience or pharmaceutical sciences., • Significant industry experience delivering PK/PD modelling and simulation programmes., • In-depth knowledge of PK/PD modelling principles and methodologies, including:, • Compartmental PK, • Exposure-response modelling, • Direct and indirect response models, • Mechanistic and semi-mechanistic PK/PD, • Disease progression modelling, • Population modelling approaches, • Experience using relevant modelling and analytical software, such as MATLAB, NONMEM, Monolix, Phoenix WinNonlin, R, or equivalent platforms., • Broad knowledge of PK, DMPK, quantitative pharmacology and translational science across drug discovery and development., • Strong understanding of the biological and pharmacological drivers of drug response, including target engagement, biomarkers, efficacy, safety and sources of variability., • Experience translating modelling outputs into practical recommendations relating to compound progression, dose and regimen selection, study design and risk mitigation., • Strong quantitative skills encompassing model development, parameter estimation, model qualification, simulation, sensitivity and uncertainty assessment, and the interpretation of complex datasets., • Experience working within multidisciplinary and matrix project teams., • A track record of scientific leadership, stakeholder engagement and influencing project decisions., • Evidence of scientific publications and presentations., • Excellent written and verbal communication skills, with the ability to explain complex quantitative findings clearly to scientific and non-specialist audiences., • A PhD in a relevant quantitative or scientific discipline., • Experience working across global teams, cultures and organisational boundaries., • Knowledge of both small molecules and larger or novel modalities, including monoclonal antibodies, antibody-drug conjugates and peptides., • Experience integrating PK, pharmacology, biomarker, efficacy and safety data to inform translational and clinical decisions., • Experience applying quantitative pharmacology analyses to regulatory submissions or interactions with regulatory authorities., • Passionate about scientific innovation and solving complex drug-development challenges., • Comfortable operating both independently and collaboratively., • Able to adapt your communication and working style to different clients, cultures and project environments., • An effective mentor who enjoys developing scientific capability in others., • Confident influencing senior stakeholders and multidisciplinary project teams., • Commercially aware, with an understanding of how scientific excellence supports client relationships and business growth., • Shape the future direction of PK/PD modelling and quantitative pharmacology within a global drug discovery and development organisation., • Influence programmes from early discovery through clinical development., • Work on scientifically diverse client projects across therapeutic areas and molecular modalities., • Collaborate with multidisciplinary scientific teams around the world., • Develop people, modelling capability and innovative quantitative services., • Build your external scientific profile through publications, conferences and industry engagement. Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 25,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. As an Equal Employment Opportunity and Affinemative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences. #J-18808-Ljbffr

JAM Recruitment Ltd is seeking a HV Commissioning Engineer for a 9 month contract in Hertfordshire, site-based. The role offers £600/day outside IR35 and requires hands-on testing and commissioning of HV equipment. You'll support substations and distribution networks, interpret electrical drawings, complete test reports, and ensure compliance with safety procedures while coordinating with project teams on energisation and handover activities. #J-18808-Ljbffr

Welwyn Garden City, United Kingdom | Posted on 22/10/2026 Location: Welwyn Garden City (HQ) – Office-based initially, with flexible and hybrid working options available Salary: £70,860 - £89,826 per annum (inclusive of a 10% Market Rate Supplement, reviewed annually) Annual pay award currently pending, anticipated circa 3%. Grade: A7 Department: Estates and Facilities / Professional Are you a proven, strategic Facilities and Estate Operations leader looking to make a direct impact on public safety and community well-being? Hertfordshire Constabulary is seeking an experienced Head of Estate Operations to lead, transform, and manage our operational estate. In this pivotal senior management role, you will hold direct responsibility for ensuring our diverse portfolio of owned and leased properties operates safely, efficiently, and in full compliance with statutory legislation. Reporting directly to the Director of Estates and Facilities, you will oversee both strategic planning and daily operational delivery—ensuring our facilities effectively support frontline operational policing while achieving best value for money. • Operational Leadership: Accountable for the operational estate, driving collaboration across departments to ensure effective delivery in line with organizational policies., • Statutory Compliance & H&S: Maintain rigorous compliance standards across all property assets. Identify emerging legislation, perform physical audits, and implement processes to manage and report on risk effectively., • Financial & Commercial Management: Oversee a £2.0m direct and £9.0m indirect budget. Manage procurement, invoice validation, cash flow forecasting, and contract performance (KPIs/SLAs) across total facilities management (TFM) framework agreements., • Strategic Collaboration: Partner with the Director of Estates and Facilities on long-term estate strategy, and collaborate with the Head of Capital Projects to design specifications aligned with the Police & Crime Commissioner’s Sustainability Charter., • Continuous Improvement: Audit reactive works to identify failure trends, develop remedial strategies, and optimize continuous service improvement., • Team Leadership & Development: Lead, mentor, and empower departmental staff, conducting PDRs and promoting organic career development within the Estates team., • Degree in Facilities Management OR a time-served Engineering Apprenticeship with a Trade Qualification in Electrical or Mechanical Engineering (ONC/OND/BTEC Level 3)., • NEBOSH General Certificate in Occupational Health and Safety., • Professional membership in a relevant industry body (e.g., IWFM/BIFM, RICS, or CIOB)., • Senior Management Experience: Managing a Total Facilities Management (TFM) model, including hard and soft services (engineering maintenance, cleaning, catering, waste management, security, grounds, etc.)., • Financial & Project Acumen: Proven track record in managing substantial budgets and delivering capital works/refurbishments. Strong understanding of CDM regulations, Planning, and Building Control., • Client-Side Leadership: Experience managing diverse work programs, contractor performance, and growth opportunities within high-density sites., • Licence Requirement: A valid UK Driving Licence (required to travel across regional sites)., • Purpose-Driven Work: Every decision you make directly supports operational policing and community safety across Hertfordshire., • Competitive Package: High-value salary package including a 10% Market Rate Supplement (reviewed annually) plus a pending pay award., • Work-Life Balance: Hybrid and flexible working options following initial onboarding and orientation at HQ., • Pension & Benefits: Access to a generous local government pension scheme, health and wellness initiatives, and staff support networks., • Vetting: This post is subject to Management Vetting (MV) checks., • Medical Assessment: Appointment may be subject to pre-employment health screening. #J-18808-Ljbffr

Pharmaron is a global contract research and manufacturing organization (CRO/CDMO)helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the UK, US, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services. We're proud of the impact we make and just last year, we supported 887 discovery projects, 1,100+ CMC programs, and 1,397 clinical trialsacross all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,300 global customers. To learn more, visit www.pharmaron.com Our Hoddesdon campus comprises more than 5,000 m² of purpose-built R&D space and houses established Drug Discovery, Process Chemistry and Analytical Chemistry teams, alongside Drug Product Development and state-of-the-art GMP facilities. We offer a highly supportive and collaborative environment that enables our employees to develop and achieve their full potential. The Integrated Drug Discovery (IDD) Services group at Pharmaron is responsible for leading and delivering drug discovery projects for our client partners. The team comprises scientific expertise and strategic leadership across medicinal chemistry, CADD, biology, DMPK and translational science. Combined with Pharmaron’s global research capabilities we design and deliver integrated programmes from target identification and hit finding through to IND filing. Working closely with our partners we define strategy, coordinate execution across teams and with an AI enabled accelerated Design–Make–Test–Analyse cycles support the progression of projects and innovative medicines towards the clinic. This Director in DMPK is a high-impact leadership role at the forefront of multi-modality drug discovery, where you will shape DMPK strategy, drive scientific excellence and deliver client programmes from target identification through to IND. Working across a global, AI-enabled platform, you will help accelerate innovative medicines towards the clinic. With a rapidly expanding department and portfolio, our Drug Discovery DMPK function is seeking experienced scientific leaders with a passion for leading DMPK science and strengthening the capabilities of our research teams. As a Director in DMPK, you will provide expert guidance and delivery across DMPK, ADME, modelling and PKPD science for integrated drug discovery projects. You will lead DMPK input into multidisciplinary project teams, work directly with client partners and collaborate internationally across Pharmaron to drive project progression and enhance our overall DMPK capabilities. • Act as the frontline DMPK discipline contact, providing leadership and influence in the design of successful DMPK, PKPD, modelling and progression strategies for multiple drug discovery projects., • Lead DMPK strategy from hit finding and lead optimisation through to candidate selection, nomination and IND-enabling activities., • Work collaboratively within cross-disciplinary matrix teams and with client partners to support the design, identification and optimisation of candidate molecules., • Develop and present scientific plans, strategies, results and achievements to external partners, internal stakeholders and senior management., • Support new business opportunities by defining strategic DMPK requirements and contributing to proposals and client discussions., • Interpret and integrate data across disciplines to guide project decisions, including the optimisation of ADME and PK properties, DDI assessments, formulation recommendations and PKPD or PBPK modelling., • Ensure robust human PK and dose predictions throughout the project lifecycle to guide programme direction and assess clinical potential., • Provide scientific leadership and expert technical direction across the department, applying innovation to scientific problem-solving and the enhancement of Pharmaron’s DMPK services., • Supervise and mentor DMPK colleagues, supporting their scientific and professional development., • PhD or equivalent experience in a relevant scientific discipline, such as pharmacology or pharmaceutical sciences., • Significant experience working on DMPK drug discovery and development projects, with a strong track record of scientific delivery., • In-depth understanding of mechanistic DMPK and ADME science, with knowledge of related drug discovery disciplines., • Multi- year experience working within multidisciplinary matrix teams and leading DMPK strategy across integrated projects and through milestones., • Expertise in scientific problem-solving and the interpretation of complex DMPK and ADME data., • Excellent written and verbal communication skills, with the ability to influence internal and external stakeholders., • Experience of supervising or mentoring scientific colleagues., • Experience of working across multiple modalities and /or experience in modelling and simulation would be advantageous. This is not simply an opportunity to inherit an established function. It is an opportunity to build, shape and lead a business with significant strategic potential. You will have the chance to: • Directly influence a diverse portfolio of drug discovery programmes across different therapeutic areas and scientific approaches., • Work closely with biotechnology and pharmaceutical partners to solve complex scientific challenges and accelerate innovative medicines towards the clinic., • Shape your career within a global organisation committed to scientific excellence, innovation and continued capability development., • Join an expanding and collaborative team that supports one another and places excellence at the heart of everything it does., • Annual performance-related bonus., • Pension scheme with employer contribution., • Option for private medical insurance scheme., • Life assurance and income protection benefits., • Generous annual leave entitlement (with options to purchase additional days and transfer remaining days to following year*), plus public holidays., • Employee Assistance Programme., • Professional membership support and continuous learning opportunities., • Access to Pharmaron's global scientific network and career development pathways. Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 25,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. As an Equal Employment Opportunity and Affimiative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences. • Job Category Scientific (Drug Discovery) #J-18808-Ljbffr

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Part-Time Cleaner North Hertfordshire & Cambridgeshire | Flexible Hours | Own Car Essential Join a new cleaning business where standards matter.We are a new, growing cleaning business building our reputation on.We are looking for a reliable and conscientious.This is not a role for someone who simply

This is a casual, project-based opportunity ideal for anyone interested in taking part in research on a part time basis, depending on their availability and profile fit.

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MULTI-DROP DELIVERY DRIVERS WANTED - Harlow £170-£200 PER DAY + MILEAGE/ 44,000 per annum Full-Time | Permanent Opportunity | Paid Training | No Delivery Experience Required We are looking for reliable, responsible and motivated individuals to join our delivery team on a permanent self-employed ba

Should you require specialist assistance to support you in this application process please contact the branch as indicated above We have a zero-tolerance policy towards sexual harassment, as defined by the Equality Act 2010 , and we take proactive steps to prevent it.

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Amazon Flex Delivery Driver - Earn £14 to £18* per hour.Deliver packages on your schedule and get paid weekly.Flexible hours and get access to a wide range of deals & discounts.Deliver with us this winter as a seasonal delivery partner.To continue delivering smiles to all our customers