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Job DescriptionMantis Innovation provides managed facility services and turnkey program management with technology-enabled solutions that target the entire building footprint. We look at the entire facility—inside and out—and can impact 70% of what a building operator allocates critical budget dollars toward, including: Strategic electricity and natural gas procurement, renewable energy, and demand response; climate impact reduction and reporting, net zero strategies, and sustainability planning; roofing, solar, HVAC assessment management, pavement, building envelope, data center optimization, and EV charging; lighting/LED retrofits, HVAC/mechanical systems, and BMS/BAS improvements and implementation. The Energy Engineer/Project Developer (Mechanical) supports the evaluation, development, and execution of energy efficiency projects across industrial, manufacturing, pharmaceutical, distribution, and complex commercial facilities. This role focuses on existing mechanical systems' performance, cost, constructability, and operational reliability. This role combines technical field work, engineering analysis, and solution development. The ideal candidate has strong mechanical systems expertise, can confidently interface with customers, and is comfortable balancing both field-based assessments and detailed engineering calculations. The role requires strong independent engineering judgment, the ability to evaluate facilities end-to-end, and the discipline to translate findings into actionable project scopes. The Mechanical Solution Engineer works cross-functionally with Technical Solutions, Mechanical, BMS, and Sales teams to support project development from initial assessment through client delivery. Field Assessment & Existing Conditions Analysis • Evaluate mechanical systems including HVAC, process cooling/heating, and related infrastructure in operating facilities both on-site and using remote tools., • Conduct site assessments independently and document system condition, constraints, and improvement opportunities. Identify and document existing equipment, control strategies, and operational issues., • Analyze system performance, operational risks, and lifecycle considerations., • Interpret utility data, system loads, and operating profiles as inputs to project development. Project Development & Technical Scoping, • Develop clear mechanical project scopes, assumptions, and technical recommendations., • Perform engineering calculations, including load calculations, equipment sizing, and energy savings analyses that meet utility technical review standards., • Support feasibility analysis, cost modeling, and constructability considerations, • Partner with internal engineering, BMS, and service teams to refine solutions, • Ensure recommendations are grounded in operational reality, not theoretical optimizationCross-Functional Collaboration, • Work closely with Mechanical, Service, and BMS teams to align project intent and execution approach., • Support handoff of defined scopes to delivery teams., • Participate in internal technical reviews and problem-solving discussions., • Interface with vendors and contractors as needed during project definition. Client & Stakeholder Communication, • Meet with internal and external stakeholders to review findings, discuss recommended measures, and support solution development., • Communicate technical findings clearly to both technical and non-technical stakeholders, • Support preparation of reports, exhibits, and presentations related to mechanical projects, • Maintain a client-facing presence appropriate to an engineering advisory role., • Coordinate with utility representatives to ensure projects qualify for incentive programs.MINIMUM QUALIFICATIONS, • Bachelor’s degree in Mechanical Engineering or a related engineering discipline, • 2+ years of experience in mechanical engineering, energy audits, facilities engineering, or industrial systems analysis, • Working knowledge of HVAC and mechanical systems in complex facilities, • Strong communication skills and comfort interacting with customers, • Demonstrated ability to perform independent engineering analysis, • Ability to travel locally with occasional national travel (up to ~20%)PREFERRED QUALIFICATIONS, • Experience in industrial, manufacturing, pharmaceutical, or distribution environments., • Experience with building performance standard policies, LEED certification, etc., • Exposure to building automation systems (BMS) and controls integration., • Familiarity with lighting systems or service operations is a plus., • Certified Energy Manager (CEM) or similar technical credential (not required)., • Engineer-in-Training (EIT), PE track, or Professional Engineer (PE).COMPETENCIES, • Strong analytical and problem-solving capability, • Ability to work independently and manage ambiguity, • Clear technical communication skills., • Strong organizational skills with the ability to manage multiple active efforts., • Professional, client-facing presence., • Collaborative mindset with service and delivery teams. MATERIAL AND EQUIPMENT DIRECTLY USED, • Laptop and standard office equipment, • Engineering and data analysis software, • Microsoft Excel and reporting tools, • Personal protective equipment (as required for site visits)WORKING ENVIRONMENT/PHYSICAL ACTIVITIES, • Combination of office, remote, and active facility environments., • Ability to walk job sites, access mechanical rooms, and perform visual inspections.

Job DescriptionMantis Innovation provides managed facility services and turnkey program management with technology-enabled solutions that target the entire building footprint. We look at the entire facility—inside and out—and can impact 70% of what a building operator allocates critical budget dollars toward, including: Strategic electricity and natural gas procurement, renewable energy, and demand response; climate impact reduction and reporting, net zero strategies, and sustainability planning; roofing, solar, HVAC assessment management, pavement, building envelope, data center optimization, and EV charging; lighting/LED retrofits, HVAC/mechanical systems, and BMS/BAS improvements and implementation. The Mechanical Solutions Engineer supports the evaluation, development, and execution of energy efficiency projects across industrial, manufacturing, pharmaceutical, distribution, and complex commercial facilities. This role focuses on existing mechanical systems' performance, cost, constructability, and operational reliability. This role combines technical field work, engineering analysis, and solution development. The ideal candidate has strong mechanical systems expertise, can confidently interface with customers, and is comfortable balancing both field-based assessments and detailed engineering calculations. The role requires strong independent engineering judgment, the ability to evaluate facilities end-to-end, and the discipline to translate findings into actionable project scopes. The Mechanical Solution Engineer works cross-functionally with Technical Solutions, Mechanical, BMS, and Sales teams to support project development from initial assessment through client delivery. Field Assessment & Existing Conditions Analysis • Evaluate mechanical systems including HVAC, process cooling/heating, and related infrastructure in operating facilities both on-site and using remote tools., • Conduct site assessments independently and document system condition, constraints, and improvement opportunities. Identify and document existing equipment, control strategies, and operational issues., • Analyze system performance, operational risks, and lifecycle considerations., • Interpret utility data, system loads, and operating profiles as inputs to project development. Project Development & Technical Scoping, • Develop clear mechanical project scopes, assumptions, and technical recommendations., • Perform engineering calculations, including load calculations, equipment sizing, and energy savings analyses that meet utility technical review standards., • Support feasibility analysis, cost modeling, and constructability considerations, • Partner with internal engineering, BMS, and service teams to refine solutions, • Ensure recommendations are grounded in operational reality, not theoretical optimizationCross-Functional Collaboration, • Work closely with Mechanical, Service, and BMS teams to align project intent and execution approach., • Support handoff of defined scopes to delivery teams., • Participate in internal technical reviews and problem-solving discussions., • Interface with vendors and contractors as needed during project definition. Client & Stakeholder Communication, • Meet with internal and external stakeholders to review findings, discuss recommended measures, and support solution development., • Communicate technical findings clearly to both technical and non-technical stakeholders, • Support preparation of reports, exhibits, and presentations related to mechanical projects, • Maintain a client-facing presence appropriate to an engineering advisory role., • Coordinate with utility representatives to ensure projects qualify for incentive programs.MINIMUM QUALIFICATIONS, • Bachelor’s degree in Mechanical Engineering or a related engineering discipline, • 2+ years of experience in mechanical engineering, facilities engineering, or industrial systems analysis, • Working knowledge of HVAC and mechanical systems in complex facilities, • Strong communication skills and comfort interacting with customers, • Demonstrated ability to perform independent engineering analysis, • Ability to travel locally with occasional national travel (up to ~20%)PREFERRED QUALIFICATIONS, • Experience in industrial, manufacturing, pharmaceutical, or distribution environments., • Experience with building performance standard policies, LEED certification, etc., • Exposure to building automation systems (BMS) and controls integration., • Familiarity with lighting systems or service operations is a plus., • Certified Energy Manager (CEM) or similar technical credential (not required)., • Engineer-in-Training (EIT), PE track, or Professional Engineer (PE). COMPETENCIES, • Strong analytical and problem-solving capability, • Ability to work independently and manage ambiguity, • Clear technical communication skills., • Strong organizational skills with the ability to manage multiple active efforts., • Professional, client-facing presence., • Collaborative mindset with service and delivery teams. MATERIAL AND EQUIPMENT DIRECTLY USED, • Laptop and standard office equipment, • Engineering and data analysis software, • Microsoft Excel and reporting tools, • Personal protective equipment (as required for site visits)WORKING ENVIRONMENT/PHYSICAL ACTIVITIES, • Combination of office, remote, and active facility environments., • Ability to walk job sites, access mechanical rooms, and perform visual inspections.

Job Description Position Summary: TScan Therapeutics is a clinical-stage biotech seeking to revolutionize life-changing therapeutics for patients by identifying novel T cells and epitopes. Reporting to the Head of FP&A, the Sr. Manager, FP&A will support management of the corporate budget/forecasts, assist in long-range planning, and support any ad hoc strategic financial analyses. This role will partner closely with R&D, Clinical, Manufacturing, and G&A teams to drive financial performance, support strategic initiatives, and enhance financial systems and reporting processes. The ideal candidate has a solid technical finance background. The individual should enjoy working in a fast-paced and rapidly growing environment. A team player with a sense of urgency will thrive in this role. Responsibilities: • Participate in company-wide annual budgeting, forecasting, and BvA management reporting activities, • Work with finance leadership in support of the financial long-range plan, • Maintain cash flow forecasting to assist in cash runway management, • Liaise between accounting and FP&A to ensure continuity and transparency across functions., • Partner with program teams to drive plan output for decision-making, • Work with key stakeholders to establish planning and reporting processes, understand system requirements, and build cost models to support business insights and value, • Perform financial analyses and valuations on business initiatives, • Create and refine cost and FTE models, benchmarks, and processes to facilitate key stakeholder decision-making, • Partner closely with the Procurement & Legal team to review vendor agreements, support contract negotiations with financial analysis, ensure purchasing processes align with budget controls and company policies and manage procurement systems (Tipalti), • Bachelor's degree in Accounting or Finance, • 6+ years of prior related accounting experience, with 3-4 years of forecast/modeling experience, • Previous experience in public biotech or pharmaceutical industry preferred, • Prior experience with financial forecasting/budgeting tool and ERP systems preferred (NetSuite, Adaptive), • Self-motivated, strategic, and analytical thinker with superior problem-solving and decision-making skills, • Ability to apply judgment with strong analytical and problem-solving skills; ability to combine attention to detail with an understanding of broader strategic context, • Strong project management skills and experience; ability to prioritize multiple initiatives concurrently with a high degree of accuracy and attention to detail TScan Therapeutics was founded in 2018 by a small group of scientists led by Dr. Stephen Elledge (Harvard Medical School/HHMI). TScan is discovering and developing novel TCR-engineered T cell therapies for the treatment of cancer. TScan’s discovery platform is centered around a breakthrough technology that enables the rapid, comprehensive, and genome-wide identification of the peptide antigen targets of T cell receptors. This technology greatly enhances our ability to understand the specific antigens that drive important disease processes, including tumor cell recognition by the immune system, self-reactivity in autoimmune disorders, and acquired immunity in infectious disease. TScan is using the platform in oncology to discover new TCR/target pairs and to rapidly move novel TCRs into clinical development. Do YOU have the anatomy of a TScanner? Our talented, compassionate and intelligent team is what makes TScan a great place to work. Our brand new offices with approximately 40,000 square feet of premium lab and office space is an environment that supports innovation, camaraderie and professionalism. We are driven, passionate, fun, flexible and team oriented. Sound like you? Apply today. EEO Statement TScan is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. TScan provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with TScan regarding a reasonable accommodation in connection with the hiring process and/or to perform the responsibilities of the position for which the applicant has applied, please contact the recruiter. Pay Transparency TScan Therapeutics’ pay ranges are established based on external market data from third-party compensation surveys and our internal benchmarking. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Individual compensation within this range is commensurate with a candidate’s specific qualifications, including education, overall experience, relevant experience, and specific skills. We strive to ensure that compensation is competitive, equitable, and aligned with the value each TScanner brings to the role. Recruitment & Staffing Agencies TScan Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to TScan Therapeutics or its employees is strictly prohibited unless contacted directly by TScan Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of TScan Therapeutics, and TScan Therapeutics will not owe any referral or other fees with respect thereto.

Job Description PhaseV is a Boston-based technology company that redefines clinical development at scale with its enterprise-ready, multi-modal AI/ML platform — accelerating decisions, de-risking trials, and driving more efficient portfolio strategies. With over $65M raised from Accel, Insight, and others, we are poised to make a significant impact on how drugs are developed and brought to market. Our tools span the entire pharmaceutical development process, from early program and portfolio decision-making through execution on registrational trials. From our Trial Optimizer platform which designs smarter clinical trials, to our ClinOps module, which enhances site selection by integrating patient-level insights, our offerings provide sponsors and CROs with a flexible, scalable toolkit for optimizing every stage of clinical development. We're already collaborating with over 40 biopharma partners, including 7 of the top pharmaceutical companies, as well as multiple CROs and biotechs, with many more in late stage discussions. The Role: We are seeking a dynamic and experienced Alliance Manager in the US to lead our efforts in managing and expanding relationships with key clients. The Alliance Manager will play a critical role in defining engagement strategy, driving revenue growth, and ensuring client satisfaction, at assigned accounts. Your Responsibilities: • Reporting to the Head of Alliance Management, this person will join the Alliance Management team and own strategy implementation at their assigned accounts., • Account Management & Growth: • Develop and execute strategies to drive expansion, up-sell, cross-sell opportunities, and revenue growth within assigned accounts., • Own the land-and-expand motion at assigned accounts, interfacing with Project Management, Business Development, and delivery teams to ensure that ongoing projects are successful and new opportunities are identified., • Act as a trusted advisor to clients, developing and maintaining strong relationships with scientific and business stakeholders • Strategic Planning: • Collaborate with the Head of Alliance Management and extended leadership team to build company strategy and roadmap., • Establish lead generation strategies for each business line and identify necessary assets, materials, and resources to implement these strategies effectively. • Internal Collaboration & Operational Excellence: • Work cross-functionally with product, project management, data science, customer success, and marketing teams to ensure seamless execution of projects at assigned accounts, • Track KPIs, including customer satisfaction, retention, and revenue growth. • Participate in externally-facing marketing, through attendance at conferences and events, solidifying PhaseV brand recognition within assigned accounts, • Develop an in-depth knowledge of company offerings to identify business opportunities. Gain an excellent understanding of the target market and ideal champions within biotech and pharmaceutical organizations. Qualifications: • 5+ years of experience in the biotech or pharmaceutical industry, with a strong focus on project or alliance management, • Solid understanding of strategic account management i.e. expansion, renewals etc., with direct experience beneficial but not required., • Team player with a desire to drive innovation and have a positive impact on the industry., • Strong technical and analytical understanding. Experience with AI/ML solutions through previous roles is a plus., • Ability to clearly communicate with a wide range of stakeholders and translate scientific insights into actionable decisions., • Engaged listener, leverages input and a variety of perspectives to develop solutions Desired Skills: • BS in a relevant field. MS, PhD, MD, or other relevant advanced degree a plus., • Background in biopharma, consulting or in similar roles at AI/ML vendors, with experience serving pharma clients., • Driven, self-motivated individual who is passionate about innovation in drug development., • Expertise in developing and delivering presentations for diverse stakeholders. What We Offer: • Join us on a mission to change the world for the better., • The opportunity to work with an amazing team passionate about making a real-world impact., • Extremely hard and diverse problem setting, in which the team is pushing the envelope., • A collaborative and dynamic startup environment., • Professional growth and development opportunities., • Competitive compensation and equity participation, • Comprehensive benefits, 401(k) match, and flexible hybrid culture

Job Description Company Summary Avalyn is reimagining the future of pulmonary fibrosis treatment with a pipeline of new inhaled formulations of approved medicines designed to reduce systemic exposure and deliver medication directly to the site of disease. Pulmonary fibrosis is characterized by scarring of lung tissue, decline in lung function, and reduced exercise capacity and quality of life, and is associated with increased mortality. Currently approved therapeutic options slow pulmonary fibrosis progression but are associated with significant toxicities that restrict their use and dosing. Avalyn's inhaled approach tackles the underlying pathophysiology of pulmonary fibrosis at its source and is designed to reduce systemic exposure and deliver medication directly to the site of disease. Avalyn's AP01 is an optimized inhaled formulation of pirfenidone, currently being studied in the ongoing MIST Phase 2b study in progressive pulmonary fibrosis (PPF). AP01 has been assessed in over 150 individuals with different forms of pulmonary fibrosis and demonstrated clinical proof-of-concept with improved efficacy and safety compared to historical data with existing therapies. The company completed two Phase 1 studies for AP02, inhaled nintedanib, for the treatment of idiopathic pulmonary fibrosis (IPF) and is planning a Phase 2 clinical trial. For more information, please visit avalynpharma.com and follow us on LinkedIn. Position Summary The Director of Clinical Operations is a senior-level position responsible for overseeing and managing the clinical operations of assigned clinical trials or program of trials. This role plays a critical role in ensuring the successful planning, execution, and monitoring of Avalyn's global clinical trials and studies. This position will report to the VP of Clinical Operations and can be remote-based anywhere in the United States. Key Responsibilities (at the study or program level): • Strategic Leadership: Develop and implement the operations plans and logistics for their assigned study or program of studies aligning with the organization's goals and objectives. Provide leadership and guidance to the clinical operations team, ensuring the successful execution of clinical programs., • Clinical Trial Management: Oversee the planning, initiation, execution, and completion of clinical trials in accordance with applicable regulations, guidelines, and standard operating procedures (SOPs). Coordinate with cross-functional teams, including outside vendors, medical affairs, regulatory affairs, data management, and biostatistics, to ensure seamless trial execution., • Resource Management: Indirectly manage external providers' study or program level resources to support clinical operations. Directly manage internal resources who support the Director's assigned studies or program level of studies. Monitor resource utilization and implement strategies to optimize efficiency and productivity., • Quality Assurance: Ensure compliance with relevant regulatory requirements, Good Clinical Practice (GCP) guidelines, and internal Standard Operating Procedures (SOPs), and other related quality standards. Work directly with the Avalyn Quality Management function to develop and maintain quality management systems to monitor and improve the quality of clinical operations processes., • Strategic Partner/Vendor Management: Oversee the selection, evaluation, and management of external partners/vendors, such as contract research organizations (CROs), central laboratories, and other service providers. Establish strong relationships with partners/vendors and negotiate contracts to ensure cost-effectiveness and high-quality deliverables., • Risk Management: Identify and mitigate risks associated with clinical trials, including protocol deviations, adverse events, and data integrity issues. Implement risk management strategies and develop contingency plans to address potential challenges and ensure patient safety., • Sponsor Oversight and Clinical Trial Management: Develop and implement clinical trial monitoring standards and best practices for effective monitoring of investigational sites and the overall quality and integrity of each assigned clinical trial or program of trials, in accordance with industry standards and practices., • Team Development: Operate as "one team" through clear and transparent communications and appropriate team building strategies. Provide mentoring, coaching, and performance feedback to enhance individual and team capabilities. Foster a culture of collaboration, innovation, and continuous improvement., • Stakeholder Engagement: Collaborate with internal stakeholders, such as senior management, clinical development teams, Key External Experts, and regulatory affairs, to align clinical operations strategies with broader organizational objectives. Establish strong relationships with external stakeholders, including investigators, study sites, and regulatory authorities., • Data Management and Analysis: Working internally/externally with data operations experts to understand the data collection, analysis, and interpretation of clinical trial data., • Business Process Improvement: Contribute to the identification of business process improvement needs or opportunities, and lead or participate in strategic and continuous business improvement initiatives in study planning & set up, study conduct & close out, vendor and CRO selection and management, budget development & management, and other initiatives to support Avalyn clinical development needs., • Personnel Management: Provide direct or indirect line management of clinical operations staff contract or consultant staff on an as-needed basis. Mentor and coach CO and other functional department team members on clinical trial operations. If in a formal line management role, conduct appropriately timed performance reviews, calibration sessions, and feedback discussions. Perform competency assessments and suggest approaches to address identified developmental opportunities., • Collaborate with the VP, Clinical Operations and colleagues from other functional groups with responsibilities in the therapeutic program (Clinical Development, Medical Affairs, Regulatory Affairs, Data Management, Finance, and Program Management) to ensure alignment of resources and tasks management to meet Avalyn business needs and to achieve Avalyn corporate goals. Qualifications and Requirements: • Degree required with a degree in life sciences, medicine, pharmacy, or a related field preferred. A Ph.D., M.D., or equivalent is appreciated but not required., • Extensive experience (typically 10+ years) in clinical operations within the healthcare or pharmaceutical industry, including significant experience in clinical trial management., • Experience in rare diseases and respiratory diseases/research highly preferred., • Strong working knowledge of applicable regulatory guidelines and requirements (e.g., FDA, EMA), as well as ICH-GCP and other relevant industry standards., • Proven leadership and management skills, with the ability to lead and motivate cross-functional teams., • Excellent organizational, planning, and project management abilities, with the capacity to handle multiple priorities and meet tight deadlines or successfully negotiate modifications., • Strong problem-solving and decision-making skills, with a focus on driving inspection readiness, continuous improvement, and operational excellence., • Demonstrated successful experience managing/overseeing Contract Research Organizations (CROs), vendors and other 3rd party suppliers, • Experience working across all phases of clinical development (Phases I – III; phase IV experience helpful), • Working medical and scientific knowledge; experience in the Respiratory Therapeutic Area strongly desirable, • Prior experience as Clinical Research Associate (CRA/monitor), Lead CRA, or Project Manager at either Sponsor, CRO helpful but not required, • Excellent communication and interpersonal skills, with the ability to effectively collaborate with internal and external stakeholders at all levels., • Experience in vendor management and contract negotiation is desirable., • Limited business travel domestically and internationally may be required., • Fully remote position., • Ability to communicate in English (written and verbal). Fluency to read or speak other languages is beneficial. Proposed pay range$215,000—$230,000 USD

Job Description Senior Medical Director, Clinical Development DynamiCure is seeking a talented, independent, and motivated clinician to help build our clinical development group. You will join a small but growing clinical development group contributing to the medical function, including designing, implementing, and communicating global clinical development plans for our vascular normalization and tumor microenvironment programs. You will serve as an internal and external clinical leader, including interactions with key academic advisors, principal investigators, patient groups, regulatory authorities, academic and industry collaborators as well as DynamiCure’s senior management and Board of Directors. As a key contributor you will be a thought partner with the VP of Clinical Development for innovative oncology development strategies, as well as a collaborator with discovery, preclinical and translational researchers focused on development of novel vascular normalization and TME modulators. Reports to: VP, Clinical Development Travel expectations: 20% Key Responsibilities and Activities • Provide oncology drug development expertise to an expanding oncology portfolio, all developed and discovered within DynamiCure., • Provide sound clinical development guidance to key stakeholders across DynamiCure., • Ensure that scientific rigor and innovation continues to be integrated into and drives DynamiCure’s oncology development strategies., • Excellent scientific standing among peers and the ability to address issues with a very high level of scientific rigor and creative solutions., • Adeptly translate oncology development program strategies into clinical study concepts that can be executed without compromising the scientific rigor of the study., • Assist in driving the timely execution of multiple assets and studies within the oncology portfolio., • Ensure excellence in both strategy and execution by partnering closely with clinical operations, biostatistics, data management, program management, and research colleagues., • Work closely with regulatory leaders to support regulatory submissions and develop regulatory strategies., • Responsible for the clinical content of clinical and regulatory documents, including protocols, INDs, CTAs, investigator brochures, CRF’s, annual IND reports, CSR’s, ISS’s, ISE’s, and clinical expert reports., • Serve as Medical Monitor and the Sponsor’s medical representative to multiple vendors and collaborators: CROs, PIs, core laboratories and other organizations involved in the implementation of clinical trials., • Responsible for analysis of clinical data, including safety monitoring in collaboration with PV., • Develop and maintain relationships and serve as medical liaison with key opinion leaders and PIs., • Organize and present at relevant clinical advisory boards, DMC’s and medical/scientific meetings., • Demonstrated capability to lead cross-functional teams., • Able to provide leadership and mentor more junior members of the clinical development team., • Able to present DynamiCure programs to external parties and contribute as needed to business development efforts. Required Education, Experience, Skills, and Competencies • M.D. or D.O. degree and clinical oncology experience required & at least 5 years’ experience working in the biotech and/or pharmaceutical industry; board certification/eligibility in oncology and MD/PhD are strongly preferred., • Hands-on oncology or I/O drug development experience within industry oncology in pharmaceutical and/or biotech company setting either for small molecules or large molecules, • Proven clinical development strategist with hands-on experience with designing, implementing, and conducting clinical trials., • Knowledge of carrying out oncology clinical trials, including knowledge of current treatment landscapes., • Strategic leadership and tactical skills, excellent initiative, and judgment, and demonstrated ability to positively represent the goals of DynamiCure., • Demonstrated ability to develop and maintain excellent working relationships with both internal colleagues and external contacts, including key thought leaders, and investigators., • Proven track record of strong collaboration skills and the ability to partner with others to implement innovative oncology development strategies., • Ability to communicate and work independently with scientific/technical personnel with excellent oral presentation skills., • Ability to think critically and demonstrated troubleshooting and problem-solving skills., • Comfortable in a fast-paced small company environment with minimal direction and able to adjust workload based upon changing priorities. Why Work for DynamiCure Around the Office: • Flexible scheduling around core hours, • Casual dress code, • Unlimited drinks & snacks Benefits: • 20 days Paid Time Off, • 10 paid holidays plus Winter Break, • Paid Family Leave, • Full benefits package including:, • Medical, • Dental, • Vision, • HSA Account with Company contribution, • 401(K) with up to 5% match, • Company paid life and AD&D insurance, • Supplemental life & AD&D insurance, • Company paid short- and long-term disability insurance, • Employee Assistance Program Employee Programs: • Employee Referral Program, • Employee Assistance Program We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, creed, national origin, ancestry, sex, age, handicap or disability, marital status, sexual orientation, gender identity or expression, pregnancy or pregnancy-related condition, genetic information, veteran status, immigration or citizenship status, military obligations, status as a domestic violence victim or a victim of sexual assault or stalking, participation in discrimination complaint-related activities, or any other status protected under applicable federal, state or local law. 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Job DescriptionInstructions for hiring Managers: Use the following template to insert the job-specific content for the role you are requesting. Note: HR will review the posting content and remove any formatting issues (highlights or boxes) before making the post live. Once all fields are completed, submit the requisition for approval. If you only press save, this will not get submitted properly. Nova Biomedical: One Global Brand. One Vision. Together under one name. Advanced Instruments and Nova Biomedical are now united under one brand, Nova Biomedical, marking a major milestone in our journey to deliver greater value to our customers. By combining our strengths, we're accelerating innovation, supporting critical workflows, and delivering world-class service across the biopharmaceutical and clinical markets. About the company At Nova Biomedical, we’re not just building instruments, we’re powering breakthroughs that improve lives. Our smart, science-driven solutions are trusted in over 100 countries to speed drug development and enhance patient care. Our integration brings together more than 70 years of scientific excellence with Nova’s cutting-edge innovation, forming a powerhouse of precision, purpose, and possibility. With FDA-registered, ISO-certified manufacturing, more than 125 FDA approvals, and industry-trusted diagnostics, we’re setting new standards in quality and reliability. Nova Biomedical is proud to be a global leader in osmolality testing and biotechnology and in vitro diagnostic (IVD) instrumentation, dedicated to advancing patient care and scientific discovery with a legacy that continues to shape the future of life sciences. With headquarters in Norwood and Waltham, Massachusetts, and a global team of nearly 2,000 employees, we’re building a collaborative, empowered culture grounded in shared values: Customer Centricity, Ingenuity, Ownership & Accountability, Collaboration, and Integrity. Working at Nova Biomedical means joining a mission-driven organization where your contributions matter. Whether you're in engineering, science, manufacturing, or support, you’ll be part of a team that values innovation, invests in your growth, and is committed to making a real-world impact on global health. Explore what’s next with us at novabiomedical.com or aicompanies.com About the role • Nova Biomedical is seeking an experienced Senior R&D Project Manager to join our Research & Development team in Waltham, Massachusetts supporting the Clinical product portfolio., • The Senior R&D Project Manager will lead and coordinate business-critical R&D projects from inception to completion. The role involves working with cross-functional teams to ensure project goals align with organizational objectives, are completed on time, and stay within budget. The ideal candidate will have a strong background in R&D processes, excellent organizational skills, and a proven ability to manage complex technical projects., • The Senior R&D Project Manager must: be detail-oriented, organized, results-driven, have proven ability to track and complete deadline-driven projects, have outstanding communication/interpersonal skills, be a positive contributor and have a strong commitment to quality. Strong time management, organizational skills, and the ability to multitask are a must. What you’ll do • Manage new product development and sustaining engineering projects through full product lifecycle (from inception through post-launch) for Clinical Whole Blood Meters and Blood Gas Analyzers, including the StatStrip, StatSensor, Prime, Prime Plus, and Allegro product lines., • Establish project schedules and budgets, prioritizing tasks, and ensuring project team members meet expected deliverables for multiple projects simultaneously., • Work closely with Product Management to drive business-critical R&D projects that will enter the new product pipeline or support the existing product portfolio., • Drive definition of project risks and creation of mitigation plans including identification of contingency plans where appropriate. Report project outcomes and/or risks to the appropriate management channels as needed—escalating issues as necessary based on project work plans and requirements., • Drive strict adherence to the Nova Design Control and Stage Gate processes., • Experience Requirements:, • 5-10 years Project Management experience working in a regulated industry, Medical or Pharmaceutical environment preferred., • Demonstrated ability to build effective working relationships throughout the business., • Strong understanding of design control, stage-gate methodologies, and product development life cycles., • Proven ability to manage complex, cross-functional projects with multiple stakeholders., • Expertise in project management tools (e.g., MS Project, Jira, Smartsheet, Confluence, etc.)., • Experience in budget management, risk assessment, and strategic planning., • Excellent leadership, communication, and problem-solving skills., • Experience producing written reports and presenting to management, • Education Requirements:, • Degree in Engineering, Science, or Project Management, • Flexible Medical, Dental, & Vision Coverage, • Competitive 401k company match, • Bonus Program, Generous PTO and paid holidays, • Generous Tuition reimbursement, • Hybrid and flexible work arrangements, • Professional development, engagement and events, • Company marketplace for lunch and snacks in our Norwood, MA, Billerica, MA and Westbrook, ME offices EEO Statement: Nova Biomedical takes pride in being an equal opportunity employer committed to hiring a diverse and inclusive workforce. As a part of our commitment to a diverse and inclusive workforce, Nova Biomedical will continue to take steps to assure that recruitment, hiring, assignment, promotion, compensation, and all other personnel decisions are made and administered without regard to race, religion, color, national origin, citizenship, sex, sexual orientation, gender identity, gender expression, veteran status, age, mental or physical disability, genetic information or any other protected class. Privacy policy

Job DescriptionCompany Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube. Job Description This is a field-based position, and candidates should reside within a commutable distance of the posted city. The Parkinson’s Disease (PD) Account Executive (AE) is responsible for maximizing business opportunities with approved on-market products (drug device combination) for the Parkinson’s Franchise. The PD AE will develop and maintain strategic business relationships with accounts through interactions with approved Movement Disorder Specialists, Neurologists, Advance Practice Providers, Health Care Professionals, nurses, executive level personnel, department managers, and various other support staff. Business relationships will focus on increasing education on product benefits/risks and awareness of current therapeutic gaps, consistent with approved labels, developing new business and expand current business, maximizing resource utilization, and increasing sales aimed at achieving sales plan for the assigned Parkinson’s product portfolio. The PD AE will also focus on building and maintaining successful and compliant working relationships with Parkinson’s Advocacy, Support groups, and other groups that support Parkinson’s patients. Key Job Responsibilities: • Delivers effective on-label technical and scientific presentations/sales calls utilizing approved data and resources to appropriately highlight the benefits and risks of the product and create awareness of product solution addressing gap in therapeutic area - resulting in sales quota achievement., • Leverages opportunities to understand and address customer needs. Builds and maintains relationships across accounts that result in opportunities to benefit patients and HCPs. Consistently partners with AbbVie in-field and in-house teams to identify, design and/or adapt appropriate approaches and tactics., • Serve as lead US Commercial contact with targeted accounts in assigned geography. Appropriately and compliantly addresses needs of customer and patients through expert knowledge of AbbVie’s environment of care approach., • Creates, implements and communicates strategic and tactical plans for targeted accounts. Monitor and report sales progress. Provide routine communications to all internal and external (as applicable) stakeholders., • Attend and actively participate in local neurology society meetings, conferences, patient programs, support groups, advocacy events, etc., some of which occur in the evenings or weekends. Represent AbbVie and assigned products at such venues to build or enhance relationships and education on product, increasing awareness. Channel key information, developments or findings to internal partners/stakeholders. All attendance and communications in these forums are within OEC and Legal guidance with all product discussions on-label., • Based on individual accounts, customers and geographical dynamics, create and development business strategy, territory account plans, align appropriate resources to support tactic execution and adjust as needed., • Remain current on all clinical, market, and payer developments, trends, and issues specific to Parkinson’s Disease., • Complete all AbbVie required training and maintain adherence to all company policies and OEC/Legal procedures., • An essential requirement of your position is to meet health care industry representative (HCIR) credentialing requirements for entry into facilities and organizations that are in your assigned territory. These HCIR credentialing requirements may include, but not limited to, background checks, drug screens, and proof of immunization/vaccination for various diseases., • Represent AbbVie as a partner of choice in the Parkinson’s and Neuroscience space with HCP and Patient Organizations, • Driving a personal auto or company car or truck, or a powered piece of material handling equipmentQualifications, • Bachelor's degree in health, sciences, pharmacy or business-related field preferred or relevant and equivalent industry experience required., • 3+ Years of Health Science Field or Sales experience with a minimum of 2 years in pharmaceutical sales. In lieu of degree 8+ Years of Health Science Sales experience with minimum of 4 years in pharmaceutical sales., • Demonstrated ability to network and partner effectively across functional areas., • Excellent organizational/project management and demonstrated leadership skills., • Proven record of managing multiple stakeholders in complex environments., • An essential requirement of your position is to satisfy all applicable health care industry representative (HCIR) credentialing requirements to gain and maintain entry into facilities and organizations that are in your assigned territory. You must also be in good standing and/or eligible to obtain these credentials., • Parkinson’s, Neuroscience, and/or Specialty pharma with 5+ years of Account Management experience with high level performance, • Specialty Pharmacy product / Medical device and/or medication pump delivery sales experience (i.e., Diabetic pump), • Previous pharma leadership experience or Formal in-house development role in training, marketing, or other areas, • Pharmaceutical launch experience (complex and novel products) in sales, training, marketing, or other roles, • Experience providing education and partnering with Advocacy organizations and support groups, • Consistent top performer, history of successful sales performance in a challenging market space or product portfolio, • Strong business acumen: individual accountability and ownership of territory with ability to multitask in a proactive manner, solving problems and influence without authority, • Proven advanced sales skills, ability to communicate novel or complex products and process while keeping it simple and overcoming customer concerns, advancing sales and gaining new business, • Excellent communication and presentation skills, ability to build credibility and trust in a collaborative manner with both internal and external stakeholders, • History of navigating the matrix environment within accounts and complex customers such as IDNs, Academic Institutions, Hospitals, Large Groups practices, etc. External: Hospitals, Health Systems and Group Practices. Internal: Sales and marketing teams, integrated Managed Health Care, Brand Teams. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: * The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this postingbased on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more orless than the posted range. This range may be modified in the future. * We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. * This job is eligible to participate in our short-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paidand may be modified at the Company’s sole and absolute discretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

Job DescriptionJob Description The Director of Market Access Pricing & Analytics is a key leader within the US Market Access team, responsible for delivering insights that drive pricing, contracting, and reimbursement strategies. This role blends advanced analytics, strategic thinking, and cross-functional leadership to support critical business decisions and improve patient access. The Director will identify opportunities, assess risks, build stakeholder alignment, and translate data into actionable strategies that advance market access objectives. Qualifications Pricing & Contracting (40%) • Develop analytical insights to inform pricing, contracting, and reimbursement strategies across brands and channels., • Build robust financial and business case models to evaluate pricing and contracting opportunities within payer markets and commercial agreements., • Conduct advanced quantitative analyses, including rebate modeling, formulary positioning, competitive dynamics, and scenario planning, ensuring alignment with business and financial goals., • Partner closely with Market Access and Finance to deliver data-driven recommendations supporting contracting strategies., • Collaborate with Legal to draft, review, and execute compliant, high-quality contracts., • Build and enhance forecast and impact models reflecting pricing assumptions, discounts, rebates, and environmental risks., • Analyze segment performance, report trends, and assess implications for the company’s financial outlook., • Create and maintain tools supporting Gross-to-Net (GTN) forecasting, ensuring integration with enterprise financial projections in partnership with Finance and Forecasting teams., • Develop models and analyses to support both in-line and pipeline products., • Conduct and contribute to market access research and analytics to inform pricing, access, and contracting decisions., • Bachelor’s degree required; advanced degree (MBA, MPH, MS, or PhD) preferred., • 8+ years of experience in market access, pricing, analytics, finance, or related pharmaceutical/biotech roles., • Strong expertise in pricing, contracting, reimbursement, and Gross-to-Net modeling., • Advanced analytical, modeling, and forecasting capabilities., • Proven ability to influence cross-functional stakeholders and translate complex data into clear, actionable insights., • Experience managing projects, vendors, and cross-functional initiatives. Additional Information Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $190,000 - $261,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location. Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable) Benefits: • Competitive salary and annual bonus., • Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more., • Generous parental leave and family planning benefits. Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.

Job Description Are you excited about the possibilities of AI to make an impact on the pharmaceutical and life sciences industry? If so, we want to meet you. As an Enterprise Account Executive, you will be tasked with showcasing the value of AI solutions in the sector, specifically in the biologics and small molecule space. This position offers the opportunity to work closely with senior leadership and contribute to expanding commercial activities. The role involves managing complex sales cycles, developing relationships with senior stakeholders, and helping organizations adopt advanced technology solutions. This is a strategic and hands-on role suited for someone comfortable operating in a fast-moving, evolving business setting. Key Responsibilities: • Drive new business opportunities within pharmaceutical organizations, focusing on enterprise-level accounts., • Manage the prospecting of new clients, bringing in new logos and working with the business development representative on pipeline development., • Identify and engage key stakeholders across functions related to product development, technical operations, and manufacturing within the life sciences and pharma industry, • Develop and maintain a strong pipeline through proactive outreach, industry engagement, and collaboration with internal team, • Collaborate cross-functionally with technical and commercial colleagues to support evaluations, pilot initiatives, and customer onboarding, • Contribute to sales planning, forecasting, and market development effort, • Represent the organization at relevant industry events, conferences, and customer meetings as needed Required Experience and Skills: • Demonstrated success in enterprise sales, preferably within the pharmaceutical, life sciences, or related technology sectors., • Experience selling solutions to technical, operational, or scientific teams within regulated industries., • Ability to manage long and complex sales cycles involving multiple stakeholders., • Strong communication, presentation, and negotiation skills., • Proven ability to build credibility and relationships with senior-level decision-makers., • Comfortable working in a growth-oriented and dynamic environment., • If based in Boston, occasional office presence in the co-working is required, • Willingness to travel occasionally based on business needs (mostly within the U.S and occasionally to Europe for strategic customer meetings or industry events), • 25% travel to customers required Preferred Background • Experience working with software or technology solutions supporting pharmaceutical or manufacturing environments., • Experience working in and success in start-up environments, • Ideally at least 5 years of Enterprise Account Executive experience in a similar role, • Familiarity with emerging technologies applied to research, development, or production processes., • Excellent enterprise sales methodologies and account development strategies. Please note we manage applications off LinkedIn so you will receive updates about the status via email. Please note you can be based in the following locations: • Boston, • New Jersey, • New York, • Philadelphia, • Florida, • Washington DC 130K-150K 260-300K OTE

Job Description Compass Therapeutics, Inc. was founded in 2014 and is headquartered in Boston, MA. We are an oncology-focused biopharmaceutical company discovering and developing proprietary antibody-based therapeutics to treat multiple diseases. Our robust pipeline currently includes four clinical assets spanning all phases of development, with novel mechanisms of action, and first-in-class or best-in-class potential across multiple tumor types. Our lead clinical-stage asset, tovecimig, has completed a randomized late-stage biliary tract cancer study and we are preparing for a BLA submission. We are now at an exciting inflection point as we scale our organization to support our first product launch. This is a unique and pivotal moment to join us and help make a meaningful impact on patients' lives. For more information, visit . Our Clinical team is seeking a hands‑on strategic Senior Manager, Clinical Statistical Programmer, reporting to our Director of Biostatistics. The ideal candidate will have a proven track record of successfully leading clinical safety analysis and programming across multiple programs, in a fast-paced environment. This role combines deep technical expertise in SAS and R with ownership of ongoing safety maintenance and leadership in modern data visualization platforms. The individual will support active trials, long‑term safety monitoring, and the integration of complex data streams, including translational and real-world data (RWD). This position works onsite 4 days/week in the Brighton, MA office. Responsibilities • Lead Statistical Programming processes, support Clinical strategies, and manage the execution of programming activities across all of our clinical-stage antibody assets and drug candidates in support of commercialization., • Ensure that Compass Clinical department goals are on track to reach milestones within established timelines, while adhering to quality standards and applicable regulations., • Provide continuous programming support for active studies, ensuring safety outputs (AEs, SAEs, Labs, Vitals) remain current, validated, and inspection readiness., • Lead the production of recurring safety outputs and data packages for Data Safety Monitoring Boards and internal safety review committees., • Oversee medical coding outputs (MedDRA, WHO Drug) and perform clinical-to-safety database SAE reconciliation to ensure data integrity., • Lead the development of interactive dashboards and exploratory tools using platforms such as Spotfire, R Shiny, or R-based frameworks., • Create and maintain customized patient profiles to facilitate efficient medical monitor and safety physician reviews., • Partner with Biostatistics and Clinical Safety teams to translate clinical questions into actionable visual analytics and early trend identification., • Build and maintain reusable SAS/R macros and standard templates to improve programming efficiency and consistency across the portfolio., • Develop and execute periodic data quality checks to identify anomalies, trends, or emerging issues early in the study lifecycle., • Design and maintain complex derived variables and analysis-ready datasets to support evolving reporting requirements., • Ensure all programming documentation and datasets meet high standards for regulatory submissions and audit readiness., • Bachelor's degree in Statistics, Biostatistics, Computer Science, Mathematics, or a related field, and advanced degree is preferred., • 8+ years of clinical statistical programming experience within the Pharmaceutical, Biotech, or CRO industry., • Advanced proficiency in SAS (SDTM/ADaM) and R/Python for clinical trial analysis and data visualization., • In-depth knowledge and proven expertise of clinical safety data structures, medical coding standards, and SAE workflows., • Demonstrated experience leading implementation and maintaining data visualization platforms (e.g., Spotfire, R Shiny) in a clinical environment., • Preferred experience handling translational data (e.g., biomarkers, genomics, or PK/PD integration) and its associated complexities., • Prior experience acting as a programming lead or senior technical contributor with oversight of FTE or vendor-provided deliverables is ideal., • Exposure to post-marketing safety data or the analysis of real-world evidence (RWE) is preferred., • Experience identifying critical risks, ability to provide appropriate solutions and mitigate risks; strong work principles and ethical standards are required., • Strong attention to detail with the ability to balance multiple project objectives in a fast-paced, collaborative work environment. Compass provides employees with a comprehensive and market-leading compensation and benefits package. Our compensation package includes a base salary, discretionary bonus, and meaningful equity participation for every employee. Our innovative benefits offerings support holistic employee health and wellness - from subsidized medical, dental and vision premiums to health reimbursement arrangement, flexible spending accounts, gym membership, employee assistance program, life insurance, and much more. We also offer 401(k) and Roth 401(k) programs with a 6% company match. Additional benefits include company parking, commuter reimbursement, and substantial vacation and leave policies, including summer Fridays, and a winter shut down week. Beyond traditional benefits, we invest in the growth and development of our teams and individuals through programs such as company-wide training, tuition and training reimbursement, recognition awards, and comprehensive performance management. With our Compass Culture Committee, we grow and preserve our culture through: events that build camaraderie and celebrate wins both large and small, diverse employee-driven initiatives, participation in charitable causes, and other programs that align with our values.

Job DescriptionSalary: $152,000 - $183,000 Summary Visterra, Inc. is seeking to hire a Senior Scientist with strong expertise in immunology and a deep understanding of immune-related diseases, along with broad experience in the discovery and development of antibody-based therapeutics. This individual will play a key role in drug discovery programs by conceiving, developing, and implementing assays to support the discovery and validation of therapeutic antibody candidates. The successful candidate will be a collaborative team player, an effective manager, a critical thinker, and a clear communicator. The ideal candidate will have an advanced degree (Ph.D. or equivalent) in immunology, biology, biochemistry, or a related field, along with a minimum of 3 years of post-graduate research experience in a biotechnology or pharmaceutical setting. Prior experience managing early-career research scientists is required. This is a full-time, on-site position located at Visterras headquarters in Waltham, MA. Responsibilities • Design and execute experiments involving immunization strategies, antibody library generation, antibody engineering, and in vitro/in vivo characterization of antibody-antigen interactions., • Provide scientific leadership on project-based team, advancing therapeutic programs from conception through pre-clinical studies., • Effectively contributes to project strategy development by demonstrating a strong understanding of target biology and aligning experimental approaches with overall program goals., • Independently and critically analyze scientific results, troubleshoot methods, and conceive creative solutions and workflows to address challenges., • Document, analyze and interpret data for internal decision making, publications, presentations, patents and regulatory filings., • Develop research plans and manage multiple workflows and, • Manage activities at contract research organizations (CROs)., • Maintain expertise in the field by staying current to relevant literature and attending relevant conferences. Requirements • A Ph.D. or equivalent advanced degree in Immunology, Biochemistry, Biology, Biotechnology, or a related field, with a minimum of three years of post-graduate research experience in the biotechnology or pharmaceutical industry., • Experience working with immune-related diseases, with a strong understanding of disease biology relevant to therapeutic development., • Expertise in antibody discovery, including protein engineering, expression and purification, and automation of screening and characterization workflows., • Skilled in designing and executing in vitro and in vivo studies to investigate disease biology and assess efficacy, PK, PD, and mechanism of action of drug candidates., • Strong data analysis skills, with the ability to interpret complex experimental results and draw meaningful conclusions., • Excellent scientific communication skills, both written and oral, including the ability to clearly present data and concepts in meetings, reports, and publications., • Self-motivated and capable of independent work in a laboratory setting, while also contributing effectively to collaborative team environments. Other Qualifications • Experience with antibody discovery platforms, such as phage display, yeast display, and next-generation sequencing (NGS), as well as antibody binding characterization techniques such as biolayer interferometry (BLI) and surface plasmon resonance (SPR)., • Experience with flow cytometry (FACS) and a range of immunological techniques, such as ELISA, multiplex cytokine assays, and immune cell profiling., • Experience with high-throughput automation technologies, such as a Tecan liquid handling robot., • A proven track record of working in a dynamic team of scientists, early-career research associates Company Visterra is a clinical stage biotechnology company committed to developing innovative antibody-based therapies for the treatment of patients with kidney, immune-mediated and other hard-to-treat diseases. Our proprietary technology platform enables the design and engineering of precision antibody-based product candidates that specifically bind to, and modulate, key disease targets. Applying this technology to disease targets that are not adequately addressed by traditional therapeutic approaches, we are developing a robust pipeline of novel therapies for patients with unmet needs. Visterras pipeline has multiple clinical-stage assets and one approved therapeutic, sibeprenlimab. As a member of the Otsuka family of companies, we are uniquely positioned as a small, dynamic, nimble and innovative organization where individuals and teams are empowered to make big impacts while benefiting from the support, strength, stability and long-term perspective of a 100-year-old global company. Visterra has approximately 105 employees and is located in Waltham, Massachusetts. Visterra provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

Job DescriptionRole Summary • Responsibilities: You will be responsible for developing economic models to inform decisions on the efficient allocation of resources available to healthcare providers, and communicating these insights to a variety of stakeholders, • Salary: $75,000 to $80,000 per annum depending on previous experience and education (please note this is a standardized, non-negotiable salary), • Benefits: Hybrid working options that allow you to work from home up to 50% of your time, generous holiday allowance, flexible working hours, private medical and dental insurance, 401K plan, life insurance, full funding for external training, comprehensive travel insurance and more, • Role Type: Full-time, permanent, • Start Date: We are currently recruiting for start dates starting from Quarter 2 of 2026 and you will be asked to state your availability on your application form, • Location: This role is available in our Boston office About the Role Health Economists at Costello Medical develop economic models to inform decisions on the efficient allocation of resources available to healthcare providers, and communicate these insights to a variety of stakeholders in the healthcare industry. Economic models within the realm of healthcare are quantitative assessments of the impact of healthcare treatments, practices and policies, either through cost-effectiveness analyses or separate cost and benefit considerations. These models are typically built in Microsoft Excel, R, or C++, employing universal mathematical and statistical modelling techniques. Model development can frequently involve fitting statistical distributions and parametric survival curves to clinical data and therefore requires a good knowledge of statistics. In this role, you will typically be working on multiple projects at any one time, starting at around 3 to 4 when joining. The models developed by our Health Economists have real-world implications, aiming to improve the efficiency of healthcare systems by using robust methodological frameworks to inform decision-making. Producing an economic evaluation therefore requires Health Economists to: • Research and critically appraise medical and economic literature, • Liaise with external medical professionals, • Work collaboratively and build relationships with colleagues across healthcare disciplines, • Understand the theoretical health economic framework and apply this to the project at hand, • Build high-quality, technically robust and clinically valid models in Microsoft Excel or other software, • Interpret and analyze model results, producing technically accurate written reports of methodologies and outcomes Hybrid Working Policy: We recognize that home-working can improve work life balance, reduce commuting times and costs, and provide the opportunity to juggle personal commitments. At the same time, we believe that having face-to-face time in the office holds many benefits and is central to ensuring that the community we have created, where people have a workplace they belong to and feel part of, is never lost. Therefore, we offer flexible working arrangements that allow our colleagues to work from home for up to half of the time, measured across a 2-week rolling period. Please note that as part of our wider flexible working policy, employees may work outside of Massachusetts for up to 4 weeks annually. A Day in the Life of a Health Economist To learn more about a typical day for a Health Economist at Costello Medical, please click here: Career Profile We offer many opportunities for personal and professional development at Costello Medical. Please click below to read first-hand accounts from our colleagues about their time with the company: ... Requirements About You Applicants should have a genuine interest in the healthcare industry and a strong desire to contribute to this setting. Essential requirements for the role are: • A degree level or higher qualification in a relevant discipline (minimum GPA 3.3 or equivalent). Relevant disciplines are those that demonstrate a high level of technical and mathematical ability, such as mathematics, economics, physics or computer science, • High school mathematics (minimum B grade or equivalent). AP/IB mathematic courses (minimum B grade or equivalent) are preferential but not required, • Advanced skills in Excel and knowledge of VBA. A willingness to learn new technical and programming skills is important for the role, • Excellent written and oral communication skills and the ability to explain complex modelling techniques and results to non-experts, • The ability to use your initiative and work independently, in addition to working collaboratively within project teams, • A high degree of accuracy and attention to detail, • Strong organizational skills, the ability to plan your own work effectively and demonstrate flexibility to respond to changing deadlines, • Formal degree-level or higher (i.e. postgraduate) training in statistics or modelling (minimum GPA 3.3 or equivalent), • Familiarity with other software (such as R, C++, STATA) What We Offer • A starting salary of $73,000 per annum. This increases to $76,000 for successful candidates who hold a master’s or PhD qualification. Please note that this salary is standardized and non-negotiable, • Private medical insurance with a company contribution, • Dental and vision cover, • 23 days’ vacation leave increasing by 1 day to a maximum of 27 days. 6 public holidays plus 1 floating holiday, • The chance to work from home for up to half of your working time, • Retirement savings via a 401k plan with up to a 5% employer match, • Paid funding for external education and study leave, • Life insurance, • Comprehensive travel insurance, • Flexible and reasonable working hours The Recruitment Process Our recruitment process includes a video interview which can be conducted at your own convenience within the given time frame. Following this, you will also be sent a technical and proofreading assessment. If successful, you will be invited to an interview which will include a short presentation you can prepare for in advance. Our standard recruitment process lasts around 6 weeks, however, this can be adapted if necessary. As an equal opportunity employer, we are committed to fostering a diverse and inclusive workforce and, throughout the recruitment process, there are a number of reasonable adjustments we can provide. Please click here to read more about this and contact the People Team via should you require reasonable adjustments at any stage. We currently have start dates starting from Quarter 2 of 2026, which occur on a monthly basis. Whilst there are no set application deadlines, we strongly recommend applying as early as possible so that we can begin processing your application. The role may close when suitable candidates are found. Please note that this role is available in our Boston office. You can learn more about our office locations here: How to Apply You are required to submit your resume and a cover letter via our online application form. In your cover letter, you must explain why you think you would be suited to the role and why you would like to join Costello Medical, with examples to support both. Your resume should clearly state the dates of all qualifications and grades achieved where applicable. While we embrace Artificial Intelligence (AI) technologies to innovate and improve processes, we want to understand your unique skills and experiences throughout the recruitment process. Therefore, if you use AI to assist with your application, we recommend that you do not rely solely on this technology to generate your application materials. As your role may involve developing new written content from scratch and handling confidential data that cannot be uploaded to AI technology, it is important for us to assess your own skills and abilities. Please contact the Talent Acquisition team at if you have any questions about the role or application process. Visa Sponsorship We welcome applications from international candidates, but we are unfortunately unable to provide visa sponsorship for working visas. Therefore, you must have the right to work in the US independently from the company. However, we are able to consider those on a temporary visa, such as an OPT visa.

Job Description Whether you are working in a Pharmacy looking for additional income, an established healthcare sales professional, or looking to break into Medical Sales, Healthcare Marketing Group, LLC is a great opportunity for you. As a Pharmacy Relationship Manager, you will help drive the growth of our company through building and retaining customer relationships. You can even change the way healthcare is delivered to Americans. Our Pharmacy Savings Card works like GoodRx and SingleCare. With savings of up to 80% off prescriptions, we provide the highest discounts in the industry! We are now seekingPharmacy Relationship Managers in your area!* What does a Pharmacy Relationship Manager do? • Educate Pharmacy Staff about how their customers can save up to 80% on prescriptions, • Provide Savings Cards by engaging with medical offices and educating Office Staff about how their patients can save up to 80% on medications What you need to qualify: • Pharmaceutical/medical sales experience is preferred but not required, • Sales skills with a proven track record, • Exceptional interpersonal skills (building strong relationships), • Excellent verbal and written communication skills, • Ability to work independently to oversee accounts and increase revenue, • Reliable transportation (this position is partially remote and you will be visiting medical professionals in your area) *We are currently hiring Pharmacy Relationship Managers in the San Antonio metropolitan area. Please only apply to one city; your desired territories will be discussed during the interview. Benefits Training and compensation: • We include comprehensive training and ongoing coaching, • Monthly Bonuses, • Great Commission!

Job DescriptionMentor Technical Group (MTG) provides a comprehensive portfolio of technical support and solutions for the FDA-regulated industry. As a world leader in life science engineering and technical solutions, MTG has the knowledge and experience to ensure compliance with pharmaceutical, biotechnology, and medical device safety and efficacy guidelines. With offices in Caguas, Puerto Rico, and Boston, United States, we serve life sciences clients in six global markets: United States, Puerto Rico, Dominican Republic, Mexico, Germany, Canada, and South America. Job Responsibilities: • Experience performing calibrations in Pharmaceutical Industry Environment. Biotechnology preferred., • Strong Knowledge in tolerance calculation, • Experience in Calibration system assessment, • Strong knowledge in process tolerance evaluation., • Process Instrumentation/ Calibration to manage calibration program., • Experience performing calibrations to Bioreactors, Utilities, Formulation, Aseptic Areas., • Experience in Blue Mountain (RAM), Calman, or Procal Software is highly preferred.Must possess experience in:, • Temperature, • Technologies, • Pressure, • Humidity, • Flow, • Mass, • PH, • Conductivity, • Dimension and Electrical, • Knowledge in cGMP, • Associate degree in Instrumentation Engineering Qualifications Requirements/Knowledge/Education/Skills: • AD, Instrumentation Technology, and or Electronics., • While performing the duties of this job, the employee is regularly required to use hands to finger, handle, feel, or operate equipments, tools, or controls. The employee frequently is required to stand, walk, talk, or hear; sit; climb or balance, stoop, kneel, crouch or crawl; and smell. The employee may lift and/or move up to 25-35 pounds and occasionally lift and/or move up to 50 pounds. Specific vision abilities required by this job include close vision, distance vision, color vision, depth perception, and the ability to adjust focus., • He / she may frequently work inside weather conditions, near moving mechanical parts, exposed to wet and or humid conditions, and an odorous atmosphere, may be exposed to fumes and the risk of electrical shock, and occasionally work on ladders in high places, in small spaces, such as lift/metering stations, manholes, tanks and wet wells. The noise level in the work environment is usually moderately loud. Mentor Technical Group es un empleador que ofrece igualdad de oportunidades y todos los solicitantes calificados recibirán consideración para el empleo sin importar raza, color, religión, sexo, orientación sexual, identidad de género, información genética, origen nacional, estado de veterano protegido, estado de discapacidad o cualquier otro grupo protegido por ley. Mentor Technical Group is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law. Powered by JazzHR AgGAvLFjgS

Job DescriptionAt Kelonia Therapeutics, our ambitions are bold: to dramatically expand the benefit and reach of genetic medicines. Our goal is to change what’s possible for genetic medicine by building the capabilities, experience, and commitment to bring life-saving medicine to every patient in need. We are a human-first company, driven by a mission to develop transformative genetic medicines for patients and their loved ones. We have brought together pioneers in cell and gene therapy, guided by extraordinary scientific founders and a team committed to turning breakthrough science into real-world impact. As we grow, we are building a culture that values rigor, collaboration, and care for one another. Are you ready to be a part of our remarkable journey? We're looking for someone exceptional to join our growing team as SVP/VP, Technical Development Operations & Strategy. We’re seeking an inspiring leader to architect and scale Technical Operations across the development lifecycle, including process, analytical, formulation development, internal manufacturing and MSAT, and CDMO management, while ensuring cGMP compliance and advancing critical regulatory submissions. This is an opportunity to shape groundbreaking therapies, build a company from the ground up, and make a transformative impact on patients’ lives. The ideal candidate pairs deep technical expertise with strategic vision and a collaborative spirit. Join us at the forefront of innovation and help write the next chapter in gene therapy. What You Will Do • Drive the overall TDO Strategy, Vision and Strategic Growth to enable success, ensuring alignment with program and corporate milestones including control strategy, PPQ/validation path, and BLA/MAA readiness., • Establish trusted Partnership and Collaboration with Regulatory CMC and Quality., • Lead upstream, downstream, analytical, formulation and fill-finish activities; oversee tech transfer to CDMOs, set phase-appropriate specs/method lifecycle/stability, and lead comparability/bridging., • Own and optimize clinical supply (DS/DP/F&F, packaging/labeling, release/testing, cold-chain distribution) to ensure on-time, in-spec lots., • Own the preparation, review, and submission of CMC sections for global filings (IND/IMPD/CTA, NDA/BLA); author/defend content and lead FDA/EMA/HA meetings., • Partner with QA to run change control, deviations/CAPA, data integrity, and inspection readiness across internal and external sites., • Lead a high-performing, collaborative TDO Strategy team, fostering accountability, speed, and quality., • Cultivate and manage relationships with CDMOs/CMOs via QTAs/TTAs, audits, and KPI dashboards to ensure best-in-class capabilities., • Govern the TDO Strategy budget; model options for throughput, COGS, and yield improvements; communicate trade-offs and recommendations to the exec team and Board.What You Will Bring, • Ph.D. or M.S. in Chemistry, Pharmaceutical Sciences, Biochemical Engineering, or related field with 12–15+ years in CMC/Tech Ops, including small-company leadership through early clinical., • Proven success optimizing established teams/systems: tech transfer, control strategy, stability, comparability, and phase-appropriate validation/PPQ planning., • Expertise in cell & gene therapy/viral vectors or complex biologics; potency/viral safety analytics and chain-of-identity/custody highly preferred., • Regulatory leadership authoring/defending CMC; experience preparing for BLA/MAA strongly preferred., • Deep knowledge of cGMP and ICH Q-series, change control, deviations/CAPA, and inspection readiness, including oversight of external partners., • Excellence in CDMO/CMO governance and running an externalized manufacturing model with measurable KPI improvement., • Clear, concise communicator who aligns cross-functionally (QA, Regulatory, Clinical, Finance) and steers the team with data and judgment.

Job DescriptionScholar Rock is a biopharmaceutical company that discovers, develops, and delivers life-changing therapies for people with serious diseases that have high unmet need. As a global leader in the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins and named for the visual resemblance of a scholar rock to protein structures, the clinical-stage company is focused on advancing innovative treatments where protein growth factors are fundamental. Over the past decade, the company has created a pipeline with the potential to advance the standard of care for neuromuscular disease, cardiometabolic disorders, cancer, and other conditions where growth factor-targeted drugs can play a transformational role. Scholar Rock is the only company to show clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). This commitment to unlocking fundamentally different therapeutic approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. By harnessing cutting-edge science in disease spaces that are historically under-addressed through traditional therapies, Scholar Rock works every day to create new possibilities for patients. Learn more about the company’s approach at ScholarRock.com and follow @ScholarRock and on LinkedIn. Summary of Position: We are seeking a strategic, and highly collaborative Vice President & Global Head of Communications to lead our global communications function. The leader will shape and drive all enterprise, executive and business communications strategies and efforts to strengthen our reputation, engage stakeholders, and advance our business and brand across internal and external audiences. The ideal candidate will bring a bold communications vision, deep experience and perspective to a diverse range of topics and issues, a track record of influencing and enabling business strategy, and the ability to be agile and lead through complexity, change, and opportunity. This position reports to the Chief Operating Officer and will partner closely with the CEO, the entire executive team and key business leaders to ensure communications are aligned, forward-looking, and aligned with our mission to bring medicine to the communities we serve and become the next great commercial biotech company globally. Position Responsibilities: Strategic Communications Leadership • Develop and execute a comprehensive, global communications strategy that supports business priorities, enhances reputation, and drives stakeholder trust., • Architect the corporate re-branding including mission, vision, values, and corporate narrative with the COO, CEO, and executive team., • Evolve the company’s communications platform and messaging to align with the company’s strategic priorities and brand., • Act as a strategic communications advisor to the COO, CEO and executive team and lead all matters of corporate narrative, media positioning, and communications risks., • Serve as steward of the company’s voice, ensuring consistency, clarity, and mission-driven across channels and audiences.Executive Communications, • Partner with the COO, CEO and business leaders to craft impactful narratives that reinforce vision, performance, and values. Shape and oversee all executive messaging, visibility, and thought-leadership., • Work with COO and CEO on internal and external communications, including speaking opportunities, internal employee forums, board communications, media, etc.Investor Communications Partnership, • Work in close partnership with Investor Relations, the CEO and executive team to shape and evolve the company’s investor narrative., • Ensure alignment between financial performance, strategy articulation, and brand reputation., • Support earnings call preparation, shareholder letters, and investor day communications, etc.Media & Public Relations, • Lead the coordination, development and execution of integrated external communications strategies aligned with corporate and business objectives., • Elevate and drive social media strategy, content planning, and performance analytics across platforms., • Draft and oversee press releases, executive communications, thought leadership content, media statements, and corporate messaging materials., • Serve as primary media contact and cultivate relationships with industry, biotech/pharma, and business media., • Lead and a manage issues and crisis communications planning and response, • Develop and maintain strong relationships with key journalists, industry influencers, and thought leaders., • Guide and manage agencies to deliver high-quality work that reflects the company’s strategy, voice, business and goals.Events & Congress Partnership, • Lead communications for all events and congresses to ensure a positive experience and ROI for external customer-facing events. (R&D Day, CureSMA, JPM, etc.), • Work in partnership with key leaders on their event plans and objectives. Partner cross-functionally with Medical Affairs, Patient Advocacy, Marketing, Regulatory, Compliance et al to ensure messaging alignment and compliance, • Oversees the successful execution of external events, from budgeting, negotiating contracts, planning to on-site management.Internal & Employee Communications, • Inspire and inform a global workforce through strategic internal communications aligned with culture, change, and business priorities., • Support executive visibility and alignment through town halls, company intranet, and other leadership cascade tools., • Elevate internal communications using modern and new methods to increase understanding of company priorities, reinforce strategy and values, invite participation, and improve employee engagement.Brand and Marketing Collaboration, • Partner with the CBO and Brand leader to ensure alignment between brand strategy and communications narratives across paid, owned, and earned channels., • Partner with Global Commercialization and Marketing teams to launch products/solutions through storytelling, press releases, media outreach, and high-impact earned channels.Issues & Crisis Management, • Lead enterprise response to reputational issues, crisis events, and sensitive situations with strategic thought, clear guidance, and control., • Ensure the organization is prepared through robust crisis communication planning, risk monitoring, and stakeholder alignment.Team Leadership & Culture, • Design, build and lead a high-performing, global communications team., • Lead with strategy, and guide team on priorities that will make the highest impact., • Operate as a collaborative enterprise leader, modeling partnership and influence across functions and geographies.Candidate Qualifications, • Bachelor's Degree in Communications, Journalism, Public Relations, Marketing, or related field; advanced degree a bonus., • 15+ years of progressive experience in corporate communications, business line communications, or public relations with experience within biotechnology, pharmaceutical, or highly regulated industries, • Proven success in leading integrated communications strategy for a global company, ideally within a public company of similar scale and complexity; and a track record of success in media relations and social media strategy execution., • Expertise in building and evolving corporate narratives that resonate across stakeholder groups — from employees to investors, media, and regulators., • Exceptional writing and storytelling ability, particularly translating complex scientific information into clear, compelling narratives, amplifying purpose through communications., • Strong strategic thinking with ability to execute tactically. Agile leader, with the ability to act quickly and navigate day-to-day requests against strategic priorities., • Experience with modern and novel communication tools, including AI, social media and other methods to reach a large and diverse employee base and significant frontline employee population., • Demonstrated experience partnering directly with executive teams and other executive stakeholders. Ability to navigate complex issues, bring clarity to a situation, and serve as a trusted advisor under pressure., • Strong executive presence and interpersonal savvy; capable of influencing at the highest levels., • Collaborative, enterprise-minded leader who fosters alignment across diverse stakeholders., • Skilled at leading high-performing teams, building followership, and developing future talent.Scholar Rock is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

Job Description Organizational Summary Contraceptive care is basic healthcare. Yet too many patients in the U.S. struggle to access the care they need, when they need it. Founded in 2014, Upstream USA is a national, nonpartisan nonprofit dedicated to ensuring that equitable, patient-centered contraceptive care is available to everyone. Our Mission and Impact Upstream works to ensure individuals can make fully informed, autonomous decisions about the contraceptive methods that are best for them. We are currently the largest contraceptive organization in the country improving contraceptive care in primary care settings, operating in 37 states and Washington, D.C. While our foundational work focuses on partnering with healthcare organizations offering primary care, such as federally qualified healthcare centers (FQHC) and health systems, we are always evolving. We are actively pursuing additional, innovative paths to ensure every patient has streamlined access to the contraceptive service of their choice, where and when it is most convenient for them. A Different Kind of Nonprofit Supported entirely by venture philanthropy, Upstream operates with a culture of aggressive growth and a laser focus on measurable outcomes. To maintain our independence and nonpartisan stance, we do not accept funding from the government or pharmaceutical companies. • Our 2030 Goal: We are on a mission to partner with organizations that collectively reach 5 million patients of reproductive age. Travel: 25% living in northern US region and 30% living outside the regionPosition Summary The Partnerships and Community Engagement (PCE) Lead plays a vital role in advancing Upstream's mission by supporting the Partnerships and Community Engagement team in cultivating and managing relationships with healthcare organizations and healthcare association partners. This role provides a blend of research, outreach, data management, and operational support to ensure effective recruitment, engagement, and partnership development. The Partnerships and Community Engagement Lead will help identify and qualify potential partners, prepare compelling materials, track progress through the partnership pipeline, and support communications and events that highlight Upstream's work. This role is well-suited for an accomplished professional with solid organizational and relationship-building skills who is eager to expand their business development and healthcare engagement skills. It offers the opportunity to shape partnership strategies, cultivate high-impact external relationships, and drive meaningful progress at the intersection of health equity and organizational growth. The Partnerships and Community Engagement Lead will play a key role in driving cross-functional collaboration, building core skills in prospective partner strategy, and making a direct impact on expanding access to high-quality contraceptive care in diverse communities nationwide. Essential Duties and Responsibilities Partnership Strategy & Execution (60%) • Support the regional partnership pipeline by developing and driving the end-to-end recruitment strategy for key Healthcare Organizations (HCOs) and Aggregators (multi-site organizations, health systems, and associations)., • Support complex partnership development, including identifying, cultivating, and securing high-impact collaborations that align with the organization's strategic goals and mission., • Draft and prepare materials that support recruitment, as directed by the Senior Director of Partnerships and Community Engagement., • Conduct high-level, strategic research on potential partners, market trends, and policy landscapes, creating detailed system maps of key decision-makers and influencers to inform outreach and engagement tactics., • Assist in scheduling and coordinating calls, webinars, and meetings with prospective and current partners., • Track the progress of healthcare organizations and aggregators through the recruitment pipeline and flag next steps for team members within the region., • Develop, negotiate, and finalize all partnership documentation, including Memorandums of Understanding (MOUs), Scopes of Work (SOWs), and data-sharing agreements, in collaboration with legal and program teams., • Spearhead initial outreach and qualification of prospective partners, leveraging techno tools like LinkedIn Sales Navigator and CRM data to move leads effectively through the recruitment funnel., • Design and execute a proactive recruitment strategy to build and strengthen relationships with healthcare organizations within a designated geography., • Support event coordination, such as webinars, conferences, and speaking engagements, to highlight Upstream's work., • Provide general administrative and project support to the regional Partnerships and Community Engagement team, as needed., • 5-6+ years of progressively responsible professional experience in partnership development, strategic sales, or relationship management with a minimum of 2 years in a leadership or self-directed ownership role. Experience in the healthcare, public health, or non-profit sector is highly preferred., • Demonstrated success in developing and sustaining complex partnerships, particularly within the healthcare or health equity space., • Adept at managing multiple, competing priorities and driving projects to completion with a high degree of independence., • Exceptional negotiation, presentation, and written/verbal communication skills, with the ability to articulate complex concepts to diverse audiences (e.g., C-suite executives, community leaders)., • Expert-level proficiency in CRM systems (Salesforce preferred) for pipeline management, reporting, and forecasting., • Ability to work independently and collaboratively across a distributed team. This role will require up to 25% business travel living in the region and up to 30% living outside the region. All Upstreamers can expect a minimum of 8 days of business travel per year to attend 1 annual organizational retreat and 1 or 2 annual team/department meetings. Hiring Range$95,000—$110,000 USD Pay Transparency Final offers for this position will be based upon several factors including the scope of the role, market compensation analysis, position requirements, candidate's experience level and capabilities, fairness in internal pay considerations and will be made within the parameters of Upstream USA's compensation framework and philosophy. Other Upstream Staff Expectations • All Upstreamers must be able to attend work-related in-person meetings and functions as needed., • In our hybrid work environments, there is a basic expectation that our Upstreamers will ensure that their work from home setups will have reliable access to phone and Internet to ensure connectivity to their teams., • At Upstream we gather for moments that matter for training, teaming and connection. Our teams come together for occasional in person meetings and organizational retreats. As part of our hybrid work practices, this travel expectation will be applicable for all Upstreamers, even those based remotely. Upstream USA offers a comprehensive benefit package including medical, dental, vision, life insurance, long and short term disability, 401K with a match, generous vacation, personal, sick and holiday time off, parental leave, professional development, a fitness and cell phone allowance for all full time employees and part time employees who work a minimum of 24 hours per week. Intern positions and contingent worker roles are not eligible for benefits. Hiring Process Candidates who advance in our preliminary review process will have an opportunity to discuss the position, their employment background and lived experience with a member of our talent acquisition team by telephone. Those who advance to subsequent steps in our interview process may participate in up to three rounds of meetings by Zoom or in person and in a thought exercise/case study assignment. Each round could consist of multiple meetings with various Upstreamers. If you need anything in advance of your interviews, please reach out to your recruiter. Our Culture We are dedicated to fostering a fair and accessible talent lifecycle, ensuring that every individual has the opportunity to thrive. From recruitment to career development, we strive to create a workplace where talent is recognized, supported, and empowered to contribute meaningfully. Building a strong, representative workforce is essential to our success, and we prioritize collaboration, transparency, and shared leadership to cultivate an environment where all voices are heard and valued. Our commitment extends beyond hiring—we invest in professional growth, mentorship, and inclusive workplace practices to support long-term success for our employees. You can learn more about our organization on our career site. Upstream Careers Our goal is to attract, develop and retain exceptional people, and to create a work environment that is dynamic, rewarding and enables each of us to realize our potential. Upstream is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, genetic information, gender identity or Veteran status. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. If you have a disability or special need that requires accommodation, please let us know. Upstream USA participates in E-Verify. Upstream Headquarters 2 Oliver Street, Suite 402, Boston, MA 02109 No phone calls please. Be advised that we do not ever conduct hiring interviews via text or email. Please protect yourself by learning more about our hiring practices and common red flags to look out for.

Job Description Why Join Us? As a member of the Parabilis Medicines team, you will be a part of an organization dedicated to creating extraordinary medicines for diseases with urgent unmet needs, harnessing our proprietary peptide platform to transform treatment possibilities for patients. Parabilis is a clinical-stage biopharmaceutical company dedicated to unlocking high-impact protein targets long-considered undruggable. The company has developed a new class of stabilized, cell-penetrant alpha-helical peptides – Helicons™ – capable of modulating intracellular proteins that are inaccessible to traditional drug modalities. Headquartered in Cambridge, Mass., Parabilis is advancing a focused pipeline of multiple first-in-class therapies across both rare and common cancers. Its lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between β-catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/β-catenin-driven tumors. In Phase 1 clinical trials, zolucatetide produced the first-ever clinical evidence that it can directly inhibit this interaction, once previously considered "undruggable" despite its role across multiple cancer types. Parabilis is also advancing investigational degraders of ERG and ARON into clinical development for the treatment of prostate cancer, as well as progressing other preclinical programs. Backed by a recent $305 million Series F financing, Parabilis is entering an exciting phase of growth and execution. What's the opportunity? The Vice President of Biometry will lead Parabilis's biometrics organization, overseeing biostatistics, , statistical programming, data management , clinical data science and Real-World Data to support clinical development programs from early-phase through regulatory submission. This strategic role ensures the integrity, quality, and compliance of all clinical trial data and analyses while driving innovation in data strategy and statistical methodologies. Reporting to our Chief Medical Officer, the successful candidate will serve as a key member of the Development leadership team, partnering closely with Clinical Development, Clinical Operations, Regulatory Affairs, translational/computational biology and other functions to enable data-driven decision-making and successful product development. • Lead and develop the Biometrics organization, including biostatistics, , programming, data management Clinical Data science ensuring high-quality deliverables across all clinical programs and fostering a culture of scientific rigor, accountability, collaboration and innovation., • Oversee design and implementation of statistical methodologies for clinical trials., • Champion innovative methodologies, including adaptive and model-based approaches, to support efficient and agile drug development., • Provide strategic input into drug development strategies in collaboration with program-level and functional leadership, working closely with Clinical Development, Clinical Operations, and Translational Medicine, • Ensure the integrity, high quality and traceability of clinical trial data and the accuracy of all statistical analyses. Leading to compliant deliverables in biometry, • Lead and support biometrics interactions with global health authorities, • Doctoral degree in Biostatistics or related field, • 15+ years of biometrics experience within the biotech or pharmaceutical field., • Proven track record of leading, building, and managing teams., • Demonstrated record of fostering creativity, productivity, and execution with urgency, teamwork and accountability., • Company leader who leads by example, employs expertise and influence to encourage collaboration across departments, levels, and groups to achieve key objectives, • Deep knowledge of clinical trial design, regulatory requirements, and statistical environment., • Excellent problem-solving skills, strategic thinking, and ability to work in a fast-paced, collaborative environment., • Outstanding interpersonal skills, self-awareness, and ability to manage team dynamics., • Ideally, has worked in more than one therapeutic area and has direct experience with innovative Phase 1-3 clinical study designs for oncology, • Comfort with model-based drug development and agile drug development is important, • Appreciation for observational methodologies is preferred, • Ability to articulate complex methodologies to senior executives for their understanding is required with previous experience with presenting to senior executives being ideal. Parabilis is a team of passionate pioneers who are trailblazing the future of precision medicine with the aim of making a meaningful difference in the lives of patients. The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit. • Growth-Minded. We're inventing a new class of medicines—one applicable to therapeutic targets that have been dreamt about, but always considered impossible to drug. Our work requires us to be curious, humble and adaptable., • In(ter)dependent.We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options., • Patient-focused.We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact. As an equal opportunity employer, Parabilis values an inclusive workplace and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law. 30 Acorn Park Drive | Cambridge, MA 02140 |

Job Description Director, Discovery and Translational Development – Solid Biosciences Charlestown, MA Solid Biosciences is a precision genetic medicine company focused on advancing a portfolio of gene therapy candidates targeting rare neuromuscular and cardiac diseases, including Duchenne muscular dystrophy (Duchenne), Friedreich’s ataxia (FA), catecholaminergic polymorphic ventricular tachycardia (CPVT), TNNT2-mediated dilated cardiomyopathy, BAG3-mediated dilated cardiomyopathy, and additional fatal, genetic cardiac diseases. We are advancing a diverse pipeline and delivery platform in the pursuit of uniting experts in science, technology, disease management, and care. Patient-focused and founded by those directly impacted by Duchenne, Solid’s mission is to improve the daily lives of patients living with devastating rare diseases. The Director, Discovery & Translational Development will provide scientific and strategic leadership for AAV-based gene therapy programs targeting neuromuscular diseases, with a primary focus on Duchenne Muscular Dystrophy (DMD). This role sits at the nexus of discovery, translational science, and early clinical development and is accountable for driving data-driven decisions that advance programs from preclinical development through IND and into the clinic. The Director will lead translational strategy, oversee preclinical and IND-enabling studies, and serve as a key scientific partner to Clinical, Regulatory, CMC, Bioanalytics, and Program Management. The successful candidate will combine deep neuromuscular and gene therapy expertise with industry experience and the ability to lead through influence in a highly cross-functional environment. Key Position Responsibilities • Scientific & Translational Leadership, • Own and drive the translational strategy for neuromuscular gene therapy programs, ensuring alignment between preclinical data, biomarker strategy, and clinical interpretation., • Provide scientific leadership for mechanism of action, biodistribution, transgene expression, durability, and functional efficacy across relevant disease models., • Define and oversee biomarker frameworks that link nonclinical data to clinical endpoints and regulatory expectations., • Establish data standards, success criteria, and decision points to support confident program advancement., • Program Ownership & IND-Enabling Execution, • Provide scientific oversight and accountability for IND-enabling studies, including study design, CRO execution, data review, and interpretation., • Contribute to and review regulatory-facing documents (e.g., study reports, investigator brochures, briefing packages, responses to agency questions)., • Partner with Program Management to ensure timelines, risks, and dependencies are clearly defined and proactively managed., • Support development and refinement of Target Product Profiles (TPPs) and program risk-mitigation strategies., • Cross-Functional Leadership, • Serve as a core scientific representative on cross-functional program teams, working closely with Clinical Development, Regulatory Affairs, CMC, Bioanalytics, and Quality., • Communicate complex scientific concepts and data clearly to senior leadership and executive audiences, enabling informed decision-making., • Represent DTD in internal governance forums and, as appropriate, external scientific or regulatory interactions., • Team Leadership & Development, • Provide scientific mentorship and leadership to scientists within DTD, fostering rigor, accountability, and translational thinking., • Guide experimental planning and data interpretation across the team without necessarily being hands-on at the bench., • PhD in Muscle Biology, Neuroscience, Molecular Biology, Cell Biology, Genetics, Pharmacology, or a related life sciences discipline., • Postdoctoral training in neuromuscular disease or gene therapy is preferred., • 8–12+ years of relevant experience, with substantial experience in biotechnology or pharmaceutical industry settings., • Direct experience leading or significantly contributing to neuromuscular disease programs, preferably DMD., • Demonstrated experience advancing AAV gene therapy programs through preclinical development and IND submission., • Experience engaging with or supporting regulatory interactions (FDA, EMA) is strongly preferred., • Deep familiarity with neuromuscular disease models and translational endpoints., • Expertise in molecular, histological, and functional assays relevant to gene therapy., • Strong data interpretation and critical assessment skills; able to integrate complex datasets across modalities., • Deep expertise in neuromuscular disease biology, with a strong emphasis on DMD., • Demonstrated leadership in AAV-based gene therapy development, including translational and IND-supporting work., • Strong translational mindset with the ability to bridge preclinical data to clinical hypotheses and regulatory strategy., • Strategic thinking combined with scientific rigor and attention to detail., • Proven ability to influence across functions and operate effectively in a matrixed organization. The base compensation range for this role is: $217,700 - $250,000 Base salary offered is determined through an internal analysis utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity. Regular employees are eligible to receive both short-term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward individual performance and align incentives to Solid’s long term company performance. Benefits and Solid Advantages At Solid Biosciences we offer a highly competitive total rewards and benefits package, intended to support all aspects of our employees’ lives and well-being. Additionally, for those employees working onsite at our Hood Park Headquarters, we offer a variety of onsite resources to support those working in our offices. • Competitive Health and Dental programs with flexible plan offerings, including FSA and HSA programs, • 401(k) program participation with competitive company matched contributions, • Eligibility to participate in Solid’s Employee Stock Purchase Plan, • Mobile phone subsidy for eligible employees, • Tuition Reimbursement, • Vision Coverage, • Life Insurance, • Voluntary Pet Insurance, • Employee Discount Program on Travel, Entertainment, and Services, • Employee Assistance Programs, • Daily Subsidized Lunch Delivery (onsite @ Hood Park), • Free Onsite Full-Service Gym (onsite @ Hood Park), • Employee Parking (onsite @ Hood Park), • 12 Observed Holidays and a winter shut down, • 15-day PTO Policy and a 40-hour rollover YoY, • 40-hour Sick Policy, • 8 Hour Floating Holiday

Job DescriptionMantis Innovation provides managed facility services and turnkey program management with technology-enabled solutions that target the entire building footprint. We look at the entire facility—inside and out—and can impact 70% of what a building operator allocates critical budget dollars toward, including: Strategic electricity and natural gas procurement, renewable energy, and demand response; climate impact reduction and reporting, net zero strategies, and sustainability planning; roofing, solar, HVAC assessment management, pavement, building envelope, data center optimization, and EV charging; lighting/LED retrofits, HVAC/mechanical systems, and BMS/BAS improvements and implementation. The Energy Engineer/Project Developer (Mechanical) supports the evaluation, development, and execution of energy efficiency projects across industrial, manufacturing, pharmaceutical, distribution, and complex commercial facilities. This role focuses on existing mechanical systems' performance, cost, constructability, and operational reliability. This role combines technical field work, engineering analysis, and solution development. The ideal candidate has strong mechanical systems expertise, can confidently interface with customers, and is comfortable balancing both field-based assessments and detailed engineering calculations. The role requires strong independent engineering judgment, the ability to evaluate facilities end-to-end, and the discipline to translate findings into actionable project scopes. The Mechanical Solution Engineer works cross-functionally with Technical Solutions, Mechanical, BMS, and Sales teams to support project development from initial assessment through client delivery. Field Assessment & Existing Conditions Analysis • Evaluate mechanical systems including HVAC, process cooling/heating, and related infrastructure in operating facilities both on-site and using remote tools., • Conduct site assessments independently and document system condition, constraints, and improvement opportunities. Identify and document existing equipment, control strategies, and operational issues., • Analyze system performance, operational risks, and lifecycle considerations., • Interpret utility data, system loads, and operating profiles as inputs to project development. Project Development & Technical Scoping, • Develop clear mechanical project scopes, assumptions, and technical recommendations., • Perform engineering calculations, including load calculations, equipment sizing, and energy savings analyses that meet utility technical review standards., • Support feasibility analysis, cost modeling, and constructability considerations, • Partner with internal engineering, BMS, and service teams to refine solutions, • Ensure recommendations are grounded in operational reality, not theoretical optimizationCross-Functional Collaboration, • Work closely with Mechanical, Service, and BMS teams to align project intent and execution approach., • Support handoff of defined scopes to delivery teams., • Participate in internal technical reviews and problem-solving discussions., • Interface with vendors and contractors as needed during project definition. Client & Stakeholder Communication, • Meet with internal and external stakeholders to review findings, discuss recommended measures, and support solution development., • Communicate technical findings clearly to both technical and non-technical stakeholders, • Support preparation of reports, exhibits, and presentations related to mechanical projects, • Maintain a client-facing presence appropriate to an engineering advisory role., • Coordinate with utility representatives to ensure projects qualify for incentive programs.MINIMUM QUALIFICATIONS, • Bachelor’s degree in Mechanical Engineering or a related engineering discipline, • 2+ years of experience in mechanical engineering, energy audits, facilities engineering, or industrial systems analysis, • Working knowledge of HVAC and mechanical systems in complex facilities, • Strong communication skills and comfort interacting with customers, • Demonstrated ability to perform independent engineering analysis, • Ability to travel locally with occasional national travel (up to ~20%)PREFERRED QUALIFICATIONS, • Experience in industrial, manufacturing, pharmaceutical, or distribution environments., • Experience with building performance standard policies, LEED certification, etc., • Exposure to building automation systems (BMS) and controls integration., • Familiarity with lighting systems or service operations is a plus., • Certified Energy Manager (CEM) or similar technical credential (not required)., • Engineer-in-Training (EIT), PE track, or Professional Engineer (PE). COMPETENCIES, • Strong analytical and problem-solving capability, • Ability to work independently and manage ambiguity, • Clear technical communication skills., • Strong organizational skills with the ability to manage multiple active efforts., • Professional, client-facing presence., • Collaborative mindset with service and delivery teams. MATERIAL AND EQUIPMENT DIRECTLY USED, • Laptop and standard office equipment, • Engineering and data analysis software, • Microsoft Excel and reporting tools, • Personal protective equipment (as required for site visits)WORKING ENVIRONMENT/PHYSICAL ACTIVITIES, • Combination of office, remote, and active facility environments., • Ability to walk job sites, access mechanical rooms, and perform visual inspections.

Job DescriptionCompany Description We are PrimeVigilance (part of Ergomed Group), a specialised mid-size pharmacovigilance service provider initially established in 2008. We are proud to have achieved global organic growth year after year, with staff based across Europe, North America and Asia all covering services within: Medical Information, Pharmacovigilance, Regulatory Affairs and Quality Assurance. PrimeVigilance provides first class support to our small to large pharmaceutical and biotechnology partners maintaining long lasting relationships and becoming one of the global leaders in its fields. We cover all therapy areas including medical devices. We love investing in our staff by providing an excellent training and development platform. We value employee experience, well-being and mental health and we acknowledge that a healthy work life balance is a critical factor for employee satisfaction and in turn nurtures an environment from which a high-quality client service can be achieved. Come and join us in this exciting journey to make a positive impact in patient’s lives. Job Description The role of business development within the organization is to win new Pharmacovigilance business, guide the overall business strategy and input to the board discussions to shape the business as it prepares for sustained growth and expansion. In order to maximize the potential in the business the (Executive / Senior) Director, Business Development will take responsibility for the business development strategy and client retention in an allocated sales territory or with specified accounts. The (Executive / Senior) Director, Business Development will work closely with the Business Development team and Functional Managers, to cultivate strong, long term relationships with the key decision-makers in life sciences organizations. Therefore, the ability to use scientific rigor and intellect to discuss service solutions with clients and to target new clients is crucial. Role and Responsibilities Initiates, coordinates and develops strategic plans and sales strategies within a specified region. Meets annual sales goals and objectives of a key strategic region. To manage the team to identify new business sales opportunities, and to work with the internal PrimeVigilance Team to respond appropriately to any enquiry, For example a Request for Information (RFI) or a Request for Proposal (RFP) Establish and maintain regular contact and an excellent rapport with future and current clients. Prepare and organize sponsor presentations such as bid defence meetings Manage the collection of critical information for proposal preparation To support the team to understand the RFI/RFP process and to provide detailed input Monitor and track competitor PV activities Plan and attend major industrial events and tradeshows as budgeted and required Identify new markets and research new business opportunities, identifies likely sales points within a specified territory or accounts Coordinate and manage all activities aiming to develop and retain clients Collects, compiles, analyses, and presents data related to business development in the region and reports to the VP as required Provide input and to actively support the VP Encourage open and transparent communication throughout the business development department and the wider organization. Provide reports as required for senior management and demonstrate leadership in best reporting practices Qualifications EDUCATION A minimum of a Bachelor's degree (or equivalent) and a higher level degree (Master or PhD, MBA) desirable/MBA preferred EXPERIENCE · PV Sales experience consistent with influencing and driving multiple stakeholders towards meeting the customer’s needs. · Knowledge of the PV business · Computer competency and familiarity with Microsoft Office & CRM systems · Excellent communication and interpersonal skills · Strong negotiation and analytical skills ·· Good planning, organization and problem-solving abilities. · Strong and effective presentation skills; ability to convincingly present features and benefits of service to clients · Travel according to the needs of the business development strategy and to company meetings as required Additional Information We prioritize diversity, equity, and inclusion by creating an equal opportunities workplace and a human-centric environment where people of all cultural backgrounds, genders and ages can contribute and grow. To succeed we must work together with a human first approach. Why? because our people are our greatest strength leading to our continued success on improving the lives of those around us. We offer: * Training and career development opportunities internally * Strong emphasis on personal and professional growth * Friendly, supportive working environment * Opportunity to work with colleagues based all over the world, with English as the company language Our core values are key to how we operate, and if you feel they resonate with you then PrimeVigilance could be a great company to join! * Quality * Integrity & Trust * Drive & Passion * Agility & Responsiveness * Belonging * Collaborative Partnerships We look forward to welcoming your application. #LI Remote

Job Description Natera is a global leader in cell-free DNA testing focused on changing the management of disease in reproductive health, oncology, and organ transplantation. Signatera is a personalized, tumor-informed test for molecular residual disease (MRD) assessment and surveillance monitoring in patients previously diagnosed with cancer. Signatera is covered by Medicare for colorectal cancer, muscle invasive bladder cancer, high-risk breast cancer, ovarian cancer, lung cancer, and immunotherapy response monitoring for any solid tumor. As the Head of GU Oncology Lifecycle Management, you will shape the vision and strategy for Natera's oncology product portfolio in GU cancers. Your leadership will drive a cohesive, cross-functional approach—partnering with medical, sales, business development, and other key teams—to position our products effectively and address critical unmet needs in cancer care. Reporting directly to the VP of Oncology Lifecycle Management, you will own the GU disease area strategy, and make high-impact decisions to maximize the clinical and commercial success of our oncology solutions. PRIMARY RESPONSIBILITIES: • Own the lifecycle planning and success of GU cancers, collaborating with cross-functional teams to develop and execute a strategic plan that drives usage, awareness, and advocacy across key stakeholders worldwide., • Expand Signatera access across GU tumors – prioritize key indications, own evidence roadmaps, close evidence gaps and submit for coverage, • Establish tumor-specific goals to be owned by the lifecycle team and across functions., • Serve as a critical member on clinical / medical teams, helping define and prioritize key indications while identifying and addressing evidence gaps., • Monitor performance & mitigate risks – In close partnership with Marketing team, track performance and deliver against GU commercial and medical goals, identifying potential issues / risks and implement mitigation strategies, • Serve as a critical member on commercial subteams, helping to maximize Natera potential by escalating and addressing critical barriers that limit commercial adoption., • Maintain a deep expertise in the GU cancers space by integrating real-time customer insights, publications, data presentations, competitive and market intelligence., • Shape the value proposition for Natera's oncology products in collaboration with Medical Affairs and Commercial Marketing, leveraging clinical evidence and market dynamics., • Bachelor's degree, Advanced degree preferred (MBA or PhD), • GU oncology market experience strongly preferred, • 8-10 years experience in product marketing, market analytics at a pharmaceutical / biotech company, • Previous KOL management experience preferred, • Working knowledge of oncology molecular testing / biomarkers, • ~25% travel required (advisory boards, congresses, sales / marketing meetings, customer meetings) KNOWLEDGE, SKILLS, AND ABILITIES: • Ability to lead without authority, influence and inspire individuals, • Proven strategic agility with an enterprise mindset and ability to operate with executive presence, • Ability to partner and collaborate across a broad range of internal and external partners, • Strong customer orientation and focus, particularly establishing thought leader relationships, • Proven ability to communicate the complex simply (biomarkers, multiple indications, etc.) Duties are typically performed in a remote home office setting. This position requires the ability to use a computer keyboard, communicate over the telephone/computer, and read printed material. Duties may require working outside normal working hours (evenings and weekends) at times. While the position may be based anywhere in the United States, availability during Pacific time hours is required. Travel required for this position: Yes: Anticipated percent for travel: ~25% travel required (advisory boards, congresses, sales / marketing meetings, customer meetings) The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$1—$1 USD OUR OPPORTUNITY Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! For more information, visit . Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide. All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, we encourage you to read this important information for California residents. Link: Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes. For more information: • BBB announcement on job scams, • FBI Cyber Crime resource page

Job DescriptionMantis Innovation provides managed facility services and turnkey program management with technology-enabled solutions that target the entire building footprint. We look at the entire facility—inside and out—and can impact 70% of what a building operator allocates critical budget dollars toward, including: Strategic electricity and natural gas procurement, renewable energy, and demand response; climate impact reduction and reporting, net zero strategies, and sustainability planning; roofing, solar, HVAC assessment management, pavement, building envelope, data center optimization, and EV charging; lighting/LED retrofits, HVAC/mechanical systems, and BMS/BAS improvements and implementation. The Project Developer (Mechanical) supports the evaluation, development, and execution of energy efficiency projects across industrial, manufacturing, pharmaceutical, distribution, and complex commercial facilities. This role focuses on existing mechanical systems' performance, cost, constructability, and operational reliability. This role combines technical field work, engineering analysis, and solution development. The ideal candidate has strong mechanical systems expertise, can confidently interface with customers, and is comfortable balancing both field-based assessments and detailed engineering calculations. The role requires strong independent engineering judgment, the ability to evaluate facilities end-to-end, and the discipline to translate findings into actionable project scopes. The Mechanical Solution Engineer works cross-functionally with Technical Solutions, Mechanical, BMS, and Sales teams to support project development from initial assessment through client delivery. Field Assessment & Existing Conditions Analysis • Evaluate mechanical systems including HVAC, process cooling/heating, and related infrastructure in operating facilities both on-site and using remote tools., • Conduct site assessments independently and document system condition, constraints, and improvement opportunities. Identify and document existing equipment, control strategies, and operational issues., • Analyze system performance, operational risks, and lifecycle considerations., • Interpret utility data, system loads, and operating profiles as inputs to project development. Project Development & Technical Scoping, • Develop clear mechanical project scopes, assumptions, and technical recommendations., • Perform engineering calculations, including load calculations, equipment sizing, and energy savings analyses that meet utility technical review standards., • Support feasibility analysis, cost modeling, and constructability considerations, • Partner with internal engineering, BMS, and service teams to refine solutions, • Ensure recommendations are grounded in operational reality, not theoretical optimizationCross-Functional Collaboration, • Work closely with Mechanical, Service, and BMS teams to align project intent and execution approach., • Support handoff of defined scopes to delivery teams., • Participate in internal technical reviews and problem-solving discussions., • Interface with vendors and contractors as needed during project definition. Client & Stakeholder Communication, • Meet with internal and external stakeholders to review findings, discuss recommended measures, and support solution development., • Communicate technical findings clearly to both technical and non-technical stakeholders, • Support preparation of reports, exhibits, and presentations related to mechanical projects, • Maintain a client-facing presence appropriate to an engineering advisory role., • Coordinate with utility representatives to ensure projects qualify for incentive programs.MINIMUM QUALIFICATIONS, • Bachelor’s degree in Mechanical Engineering or a related engineering discipline, • 2+ years of experience in mechanical engineering, facilities engineering, or industrial systems analysis, • Working knowledge of HVAC and mechanical systems in complex facilities, • Strong communication skills and comfort interacting with customers, • Demonstrated ability to perform independent engineering analysis, • Ability to travel locally with occasional national travel (up to ~20%)PREFERRED QUALIFICATIONS, • Experience in industrial, manufacturing, pharmaceutical, or distribution environments., • Experience with building performance standard policies, LEED certification, etc., • Exposure to building automation systems (BMS) and controls integration., • Familiarity with lighting systems or service operations is a plus., • Certified Energy Manager (CEM) or similar technical credential (not required)., • Engineer-in-Training (EIT), PE track, or Professional Engineer (PE). COMPETENCIES, • Strong analytical and problem-solving capability, • Ability to work independently and manage ambiguity, • Clear technical communication skills., • Strong organizational skills with the ability to manage multiple active efforts., • Professional, client-facing presence., • Collaborative mindset with service and delivery teams. MATERIAL AND EQUIPMENT DIRECTLY USED, • Laptop and standard office equipment, • Engineering and data analysis software, • Microsoft Excel and reporting tools, • Personal protective equipment (as required for site visits)WORKING ENVIRONMENT/PHYSICAL ACTIVITIES, • Combination of office, remote, and active facility environments., • Ability to walk job sites, access mechanical rooms, and perform visual inspections.

Job DescriptionCompany Description About AbbVie At Allergan Aesthetics, an AbbVie company, we develop, manufacture, and market a portfolio of leading aesthetics brands and products. Our aesthetics portfolio includes facial injectables, body contouring, plastics, skin care, and more. Our goal is to consistently provide our customers with innovation, education, exceptional service, and a commitment to excellence, all with a personal touch. For more information, visit . Follow Allergan Aesthetics on LinkedIn. Job Description If you live and breathe all things Digital, then we want to talk to you! Allergan Aesthetics, one of the largest bio-pharmaceutical companies in the world, is on a mission to transform the medical aesthetics business. Allergan aesthetic brands are iconic, household names and include Botox, CoolSculpting, Juvéderm among others. Allergan Aesthetics is well positioned to disrupt the multibillion-dollar aesthetics market, infusing cutting edge technology, digital marketing mastery and some of the best data scientists in the world. This is an amazing opportunity for a candidate that has a passion for digital marketing. If you want to be a part of an industry-defining team, then we want to hear from you. Allergan is a company that will inspire you to aim high with your ambition. Where you can build bridges all over the world. Where you can power ideas that drive change. And where you will act fast and drive results for customers and patients. Power your future & join our bold team. The Allergan Digital Consultant is responsible for growing Allergan’s Medical aesthetic business by delivering digital marketing consultative support to key Allergan Medical customers. This is a highly visible role both internally and externally as a member of the sales management team with a goal to appropriately promote and protect Allergan’s leadership in the aesthetic market space. • Work with some of Allergan’s top accounts and help them utilize digital marketing strategies and tactics to generate leads and nurture them all the way through to purchase., • Teach these accounts and numerous internal Allergan stakeholders the importance of various digital touchpoints in the Allergan customer journey., • Gain buy in and support for Allergan-product-focused campaigns at the practice level by building close relationships with relevant stakeholders., • Lead both in-market and online training courses to ensure Allergan’s key accounts are well positioned to take advantage of digital marketing channels to help grow their business., • Participate with the sales team in the customer targeting process, which involves the development of strategic digital marketing plans, incorporating consulting services, corporate initiatives, and hands-on account support., • Direct the development of company digital marketing programs. Manage the research, analysis, and monitoring of financial, technological, and demographic factors, and design marketing plans to capitalize on market opportunities with key accounts., • Evaluate the needs and areas of opportunity for Allergan’s key accounts and manage the development, delivery and execution of specific digital marketing enhancement programs based on account objectives., • Act as subject matter expert on best practices for digital marketing capabilities; advise accounts on process and technical execution., • Develop clear pre-call meeting objectives and ensure timely communication and follow up with customers., • Demonstrate leadership in the account selling process and provide long term competitive advantage., • Identify opportunities and speak at local, regional and/or national conferences and society meetings., • Provide oversight of digital operations and makes recommendations/solutions to operational issues.Qualifications Must be local to Detroit, MI Or Boston, MA • Bachelor’s Degree required. Master’s Degree preferred, • 7+ years’ experience in Digital Marketing, • Willingness to travel 25% of the time, • Agency experience preferred, • B2C experience preferred, • Experience working at a corporation a plus, • Sales experience a plus, • Knowledge of the Medical Aesthetic space a plus, • Must have hands-on experience with key digital marketing channels: paid search, paid social, organic social, content marketing, SEO, website optimization, email marketing, and more., • Must have a deep understanding of important digital platforms: Google Analytics, Google Ads, Facebook Ads Manager, Facebook, Instagram, WordPress CMS, marketing automation tools, technical SEO tools, and more., • Must be able to juggle dozens of accounts and projects at once; needs to be somebody who does whatever it takes to get the job done., • Must also be comfortable in a large business setting where overcommunication is needed and necessary., • Need to be able to take complex information, distill into simple, easy-to-understand content, and distribute and communicate across Allergan’s matrix organization., • Able to strategically segment large projects into smaller, actionable deliverables, effectively prioritizing a high volume of work across the business., • Continually seeks opportunities to drive process change and supports organization through change. Identifies opportunities to innovate and evolve while proactively driving new ways of working., • Expert communication, presentation and material preparation skills required., • A proven track record of personal success and ambitious undertakings., • A passion for building, bringing to market, and scaling digital products and services., • Valid driver’s license issued by the state/province in which the individual resides, and a good driving record is required. Additional Information AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

Job Description Benchling Product Manager This role will require regular, on-site presence at our client site in either Cambridge, MA or Norwood, MA This role is not eligible for relocation assistance This role will report to Head of Benchling Practice at Zifo, responsible for overseeing the Benchling rollout at one or multiple customers. The role will partner closely with Customer’s Research and Technical Development scientists to understand their scientific workflows and translate those needs into scalable, consistent Benchling solutions. The role will work closely with implementation consultants to own the end-to-end delivery of assigned projects, from requirements discovery through rollout and adoption, while ensuring solutions align with shared platform standards and long-term data strategy. • Partner with scientific teams to understand their software-related use cases and identify how Benchling can best support their business needs., • Capture user requirements and present them for manager review and approval, ensuring balance between team needs, shared platform standards and long-term scalability., • Leverage knowledge of Benchling product ecosystem to propose potential approaches during requirements gathering., • Lead requirements gathering and design workshops, translating scientific workflows into data models, templates, intake processes, and system configurations., • Analyze and translate end-to-end assay data processes - from raw data capture and metadata enrichment through transformation and reporting - into structured, scalable, Benchling workflows that are intuitive and usable for end users., • Collaborate with implementation partners to hand off requirements, review and validate delivered configurations, and drive iterative refinement through demos and user workshops., • Develop test plans, guide UAT execution, and create documentation and training materials to support user training and onboarding., • Provide user support during rollout and early adoption, • Bachelor’s or Master’s degree in a life sciences, informatics, or related discipline, • At least 5-7 years of experience in pharmaceutical research, biotech, informatics, or product adjacent role, • Hands-on experience using or administering Benchling to support scientific workflows (e.g., schemas, templates, workflow configuration), • Demonstrated ability to gather, refine, and translate user requirements into high quality requirements, design, and data model documentation to support scalable implementation and ongoing platform support, • Strong communication and facilitation skills, with the ability to lead workshops and partner effectively with scientific and technical stakeholders Preferred Qualifications, • Familiarity with R&D lab workflows (e.g. assay development, process development, flow cytometry, next generation sequencing) and a wide variety of laboratory instrumentation., • Experience with business process mapping and leading cross-functional requirements or design workshops, • Proven ability to develop fit-for-purpose data models and solutions rooted in strong product understanding and established industry standards., • Experience creating user documentation, training materials, and delivering user training, • Comfortable working with external implementation partners, • Ability to manage multiple workstreams and deliver high-quality outcomes in a matrixed environment CURIOSITY DRIVEN, SCIENCE FOCUSED, EMPLOYEE BUILT. Our culture is unlike any other, one where we debate, challenge ourselves, and interact with all alike. We are a curious bunch, characterized by our passion to learn and spirit of teamwork. Zifo is a global R&D solutions provider focused on the industries of Pharma, Biotech, Manufacturing QC, Medical Devices, specialty chemicals and other research-based organizations. Our team’s knowledge of science and expertise in technology help Zifo better serve our customers around the globe, including 18 of the Top 20 Biopharma companies. We look for Science – Biotechnology, Pharmaceutical Technology, Biomedical Engineering, Microbiology etc. We possess scientific and technical knowledge and bear professional and personal goals. While we have a “no doors” policy to promote free access within, we do have a tough door to walk in. We search with a two-point agenda – technical competency and cultural adaptability. We offer a competitive compensation package including accrued vacation, medical, dental, vision, 401k with company matching, life insurance, and flexible spending accounts. If you share these sentiments and are prepared for the atypical, then Zifo is your calling! Zifo is an equal opportunity employer, and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Job DescriptionThe Company We are Alloy Therapeutics—a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. MAY THE BEST DRUG WIN. Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, Switzerland, and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture. At Alloy, we have an ethos of “Mentorship-By-Apprenticeship” in all of our positions. We strive to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day. We ask our people who have more flexible accommodations, like this position, to appreciate their colleagues who have less flexibility. We are all one team! The Team Launched in 2023 as a division of Alloy Therapeutics, Alloy Genetic Medicines is revolutionizing the discovery of oligonucleotide therapeutics. Our AntiClastic™ Cyclic RNA platform, built on technology exclusively licensed from Dr. Sudhir Agrawal at Arnay Sciences, overcomes traditional stability and safety barriers by engineering IP-protected, configurable cyclic architectures. These cyclic structures deliver nuclease-resistant therapeutics with greater potency, durability, specificity, and in vivo stability, while reducing immunostimulation. GMED partners with pharmaceutical companies, such as Sanofi, biotech, and academic partners to discover and develop the next generation of RNA medicines. The Role As the Senior Director of Business Development for Alloy Genetic Medicines (GMED), you will support and execute business development activities that drive pipeline expansion across various GMED target audiences, achieving sustainable revenue growth through new opportunities and the development and expansion of strategic partnerships. You will manage the end-to-end sales lifecycle and process for GMED-focused opportunities, from initial outreach through contract execution, in collaboration with GMED’s Chief Business Officer on strategic and enterprise-level partnering. This high-impact role requires an experienced, entrepreneurial, and highly organized individual with a positive attitude and a “no task too small” mentality, comfortable balancing high-level commercial strategy with the hands-on execution required to build, advance, and sustain a healthy partnering pipeline. This role reports directly to the CEO of Genetic Medicines and operates in a dynamic start-up environment. The Senior Director of Business Development will partner with the Chief Business Officer (CBO) of Genetic Medicines, to close complex, enterprise-level deals and on opportunities that span multiple Alloy business units. How You’ll Drive Impact • Discover: Generate and qualify both high-value technology partnering and strategic RNA discovery service opportunities across various GMED target audiences, contributing to a balanced portfolio of partners aligned with GMED’s strategy., • Innovate: Develop and refine custom pitch decks, capability and solution statements, and case studies that translate complex scientific offerings into actionable partner solutions., • Execute: Manage the sales funnel for GMED-focused opportunities, maintaining the CRM as the single source of truth for lead progression, pipeline health, and revenue forecasting., • Collaborate: Partner with internal delivery teams—including the Scientific Team, Alliance Management, Office of Partnerships, and the Chief Business Officer—to ensure a seamless transition from “sold” to “active project.”, • Prospect for and advance new business opportunities, including technology licensing deals and RNA medicine discovery service sales, across various GMED target markets to support divisional revenue targets., • Build and maintain relationships with external partners and influencers across relevant audiences, contributing to a steady stream of qualified partnering opportunities., • Lead the end-to-end process for Requests for Proposals (RFPs), including drafting technical content and coordinating with scientific leads for GMED-aligned prospects., • Provide regular reporting to the CEO on the partnering pipeline, projected revenue, and other decision-quality KPIs, including visibility into partner mix and opportunity scope., • Conduct discovery sessions with prospective partners to translate scientific and strategic needs into tailored GMED offerings., • Represent the division at key industry conferences and networking events relevant to GMED audiences., • Partner with Legal to support the negotiation of Master Service Agreements (MSAs) and other core contracts aligned to GMED opportunities., • Degree (preferably Ph.D.) in life sciences, biochemistry, chemistry, chemical or biomedical engineering, or similar, • Proven track record in Business Development, Strategic Partnerships, or Commercial Operations within the Biotech or Life Sciences sector., • 10+ years of overall biotech industry experience, with 6+ years in Business Development, Sales, Commercial Operations, or Strategic Partnerships., • Experience supporting and leading complex contract negotiations and managing the full sales lifecycle for service-based or platform offerings., • Strong scientific fluency with the ability to bridge technical teams and commercial stakeholders., • Demonstrated ability to manage multiple priorities within a fast-paced, matrixed organization., • Proficiency in CRM systems (e.g., Salesforce, HubSpot) and executive-level reporting., • Strong communication and presentation skills, with the ability to translate complex science into clear commercial narratives. Compensation • Competitive base and equity compensation commensurate with level of experience and independence, • 401(k) company matchHealth & Family, • Generous personal and family medical, dental and vision benefits with 100% of premiums and deductibles covered, • Company-paid disability (STD, LTD) and life insurance, • Paid parental leave, • Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval)Unique Perks, • Unlimited PTO (paid time off) and flexible schedules, • Annual stipend for continuing education with commitment to your career through individualized professional development plan Additionally, this role is eligible for equity compensation, reflecting our commitment to shared success as we work together to make better medicines. We are proud to offer competitive compensation and benefits, aiming to support our team’s professional and personal well-being. If you have any questions about pay or benefits, we’re here to help. Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at . We will make every effort to respond to your request for disability assistance as soon as possible. Powered by JazzHR Ix2gcbhepP

Job DescriptionScholar Rock is a biopharmaceutical company that discovers, develops, and delivers life-changing therapies for people with serious diseases that have high unmet need. As a global leader in the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins and named for the visual resemblance of a scholar rock to protein structures, the clinical-stage company is focused on advancing innovative treatments where protein growth factors are fundamental. Over the past decade, the company has created a pipeline with the potential to advance the standard of care for neuromuscular disease, cardiometabolic disorders, cancer, and other conditions where growth factor-targeted drugs can play a transformational role. Scholar Rock is the only company to show clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). This commitment to unlocking fundamentally different therapeutic approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. By harnessing cutting-edge science in disease spaces that are historically under-addressed through traditional therapies, Scholar Rock works every day to create new possibilities for patients. Learn more about the company’s approach at ScholarRock.com and follow @ScholarRock and on LinkedIn. Summary of Position: The Senior Director, Patient Marketing (US) will play a critical leadership role in the preparation for and execution of Scholar Rock’s first U.S. commercial launch. This role will be accountable for developing and driving the U.S. patient and caregiver marketing strategy and tactical execution for apitegromab, the first and only muscle-targeted therapy for spinal muscular atrophy (SMA). This individual will own the U.S. patient brand strategy from launch through commercialization, ensuring a deeply patient-centric approach across education, engagement, and community presence. The role will lead the development of integrated, compliant, multi-channel patient programs designed to support awareness, understanding, and empowerment throughout the patient journey. As a senior leader on the U.S. Marketing Team, this role will work closely with Patient Services, Medical Affairs, Advocacy, Market Access, Legal, Regulatory, and Compliance to ensure a cohesive, high-quality experience for patients and caregivers. This is a high-impact, high-visibility role with the opportunity to shape how Scholar Rock engages with the SMA community as it brings its first therapy to patients. Position Responsibilities:U.S. Patient Strategy & Launch Execution • Lead the development of the U.S. patient and caregiver brand strategy for apitegromab, grounded in a deep understanding of the SMA community, patient journey, and unmet needs., • Own U.S. patient launch planning, including strategy, messaging, channel mix, and executional roadmap., • Translate strategy into high-quality, compliant patient-facing tactics across digital, community, advocacy-aligned, and experiential channels., • Ensure consistency and excellence across all patient touchpoints while maintaining a strong, authentic patient-centric lens.Patient Engagement & Community Leadership, • Build and maintain strong, trusted relationships within the SMA patient and caregiver community., • Lead the patient ambassador and engagement programs, including long-term retention and stewardship strategies., • Own the U.S. patient conference and event strategy, elevating Scholar Rock’s presence and impact at key national, regional, and local meetings., • Champion innovation in patient engagement, continuously evolving approaches to improve the patient experience across the journey.Cross-Functional Leadership, • Serve as a core member of the U.S. Marketing Team, partnering closely with Patient Services, Medical Affairs, Advocacy, Market Access, Regulatory, Legal, and Compliance., • Ensure strong alignment between patient marketing initiatives and patient support programs, including development of branded patient materials., • Clearly communicate and champion patient brand strategy with internal stakeholders and external partners., • Support field teams with tools, training, and resources to enable effective and compliant patient engagement at the local and regional level.Agency, Budget & Operational Excellence, • Own agency-of-record relationships for patient marketing, driving strategic value, innovation, and executional excellence., • Lead the development of patient-facing assets, event kits, and materials to support consistent execution across the field., • Manage the U.S. patient marketing and patient services marketing budget, demonstrating strong fiscal discipline and accountability., • Oversee launch readiness, promotional review processes, and ongoing optimization of patient tactics., • Conduct regular performance reviews and field training refreshers to ensure awareness, education, and effective use of patient resources.Candidate Requirements, • Bachelor’s degree required; advanced degree preferred., • 10+ years of experience in pharmaceutical or biotechnology marketing, with significant experience in U.S. patient/consumer marketing., • Demonstrated success leading patient marketing strategy and execution in specialty or rare disease environments., • Experience in neurology, neuromuscular disease, or rare disease strongly preferred., • Previous experience supporting or leading a product launch strongly preferred., • Deep commitment to patient centricity with the ability to translate insight into impactful, compliant engagement., • Strong understanding of regulatory, legal, and compliance requirements for patient-facing communications., • Proven ability to lead agencies, manage budgets, and operate effectively in a matrixed organization., • Excellent communication, influence, and stakeholder-management skills., • Entrepreneurial mindset with comfort operating in a first-launch, high-growth environment., • Willingness to travel as needed (anticipated up to ~30%).Scholar Rock is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

Job Description Biocytogen Boston Corp is a fast-growing biotech company at the forefront of innovation, equipped with broad cutting-edge technologies. Our expertise spans a wide range of therapeutic areas, including immuno-oncology , inflammatory and autoimmune diseases, neurology, cardiovascular and metabolic disorders, and more. At Biocytogen, you will have the unique opportunity to engage in both scientific and business endeavors, driving the licensing and commercialization of cutting-edge antibody assets across multiple therapeutic fields. The successful candidate will possess a strong understanding of business development and licensing and play a key role in driving strategic growth and exploring new business opportunities for the organization. Job Responsibilities: • Establish external business opportunities for out-licensing, co-development, and other structured transactions., • Lead the development and presentation of business cases of prioritized external opportunities with recommendations to management team with robust analyses, key assumptions, and risks, as well as internal and external input where necessary., • Initiate, lead and present external opportunities with limited supervision., • Lead driving cross-functional due diligence and alliance management, coordinate with R&D, CMC, Clinical, Regulatory, Operations, and Finance and executive reporting, in some instances be the main BD contact person., • Follow BD operations and transactions including proposals and TS developments,negotiations, deal closure and alliance management., • Contribute to the definition and revision of business development & licensing strategy that is in line with overall corporate and portfolio strategies., • Ph.D. in pharmacology, immunology, cancer biology, or a related biomedical science field, • Strong background in antibody drug discovery, with a deep understanding of target validation and hit-to-lead optimization, • Proven ability to interpret complex biological data (affinity, specificity, and in vivo efficacy) and translate it into a compelling therapeutic and licensing narrative, • Familiarity with current antibody modalities, including monoclonal antibodies (mAbs), bispecific antibodies, and ADCs, • Strong strategic thinking skills to align internal scientific platform capabilities with pharmaceutical partner pipeline gaps, • Medical Insurance, • Dental Insurance, • Vision Insurance, • Health Reimbursement Accounts, • Life and AD&D Insurance, • Short & Long Term Disability Insurance, • 401K with Company Match, • Paid Time Off, • Paid Sick Days & Holidays BIOCYTOGEN is an Equal Opportunity Employer. Employment opportunities at BIOCYTOGEN BOSTON CORP are based upon one’s qualifications and capabilities to perform the essential functions of a particular job. All employment opportunities are provided without regard to race, color religion, sex, national origin, ancestry, age, sexual orientation, gender identity and expression, veteran status, military status, disability, mental illness, genetic information, or any other characteristic protected by law. This Equal Employment Opportunity policy governs all aspects of employment, including, but not limited to, recruitment, hiring, selection, job assignment, promotions, transfers, compensation, discipline, termination, layoff, access to benefits and training, and all other conditions and privileges of employment.

Job Description Biocytogen is a comprehensive research and discovery service provider for biotech and pharmaceutical industry and academic institutions. Its service platform integrates preclinical studies with innovative animal models, CRISPR-based gene editing, and animal supplies, with the current focus on immuno-oncology and oncology. We are looking for a highly motivated research associate with the ability to work both independently and in a collaborative manner. Biocytogen is a fast-growing company and has an abundance of opportunities available for you to grow your career. Biocytogen is committed to nurturing junior scientists to progress within our organization, providing a supportive environment for career advancement. This opportunity is ideal for individuals who can recognize and seize learning opportunities. Job Responsibilities: ● Perform preclinical pharmacology studies in rodents. Tasks include drug administration via multiple routes (IV, IP, SC, PO etc), blood and tissue collection, and tumor volume measurement. Experience with small animal surgery is a plus. ● Communicate and coordinate with other scientists on a project team to draft, finalize, and implement study protocols. Follow protocols and independently execute tasks. ● Collect and record data. Prepare summaries of experimental procedures and results and present data in team meetings. ● Develop, perform, interpret, and troubleshoot a broad range of in vitro assays including immune cell profiling, cytokine profiling, functional assays using primary cells, as well as cytotoxicity/apoptosis assays using primary and/or cultured cells. ● Innovate and expand our assay portfolio by identifying, evaluating, and implementing new assay technologies through literature research, academic collaborations, and adaptation from other groups within the company. Requirements ● Bachelor’s or Master’s degree with 1-3 years of academic or industry research experience. Demonstrated experience in small animal handling and pharmacology is highly preferred. ● Experience with small animal handling, drug administration, and blood and tissue collection is preferred. ● Experience in cell biology, biochemistry, and/or molecular biology, in particular assay development and execution, is required. This includes cell-based assays, tissue culture, biochemical assay technologies, and protein and RNA expression analysis. ● Experience with cell culture and in vitro assays is desirable. ● Experience in primary immune cell-based assays is strongly preferred. ● Experience in flow cytometry (FACS) analysis is preferred. ● Demonstrate ability for quality execution, attention to detail, and proficiency in multi-tasking in a fast-paced environment. ● Collaborative team player. Be flexible and prioritize tasks based on team and company goals. ● Communicate effectively at all levels, within teams, with internal and external collaborators. ● Strong organizational skills. Maintain research data and records with the highest integrity. ● Ability to multitask in a fast-paced environment. Benefits • Medical Insurance, • Dental Insurance, • Vision Insurance, • Health Reimbursement Accounts, • Life and AD&D Insurance, • Short & Long Term Disability Insurance, • 401K with Company Match, • Paid Time Off, • Paid Sick Days & Holidays BIOCYTOGEN is an Equal Opportunity Employer. Employment opportunities at BIOCYTOGEN BOSTON CORP are based upon one’s qualifications and capabilities to perform the essential functions of a particular job. All employment opportunities are provided without regard to race, color religion, sex, national origin, ancestry, age, sexual orientation, gender identity and expression, veteran status, military status, disability, mental illness, genetic information, or any other characteristic protected by law. This Equal Employment Opportunity policy governs all aspects of employment, including, but not limited to, recruitment, hiring, selection, job assignment, promotions, transfers, compensation, discipline, termination, layoff, access to benefits and training, and all other conditions and privileges of employment.

Job DescriptionAre you looking to join a company where your contributions truly matter, and where you'll be part of a supportive, innovative team? MMS is a award-winning, data-focused clinical research organization (CRO). We pride ourselves on being a Great Place to Work certified organization, recognized for our exceptional culture and industry best employee retention rate. We support the pharmaceutical, biotech, and medical device industries with our proven, scientific approach to complex trial data and regulatory submission challenges. With a global footprint across four continents, MMS not only maintains an industry-leading customer satisfaction rating but also fosters a collaborative and inclusive work environment where employees can thrive. Join us at MMS and be part of a team that is shaping the future of clinical research. Discover more about our exciting opportunities and why MMS is a great place to advance your career. Visit or follow MMS on LinkedIn. This person will participate in the development, writing, and management of highly technical nonclinical documents. This is a full-time, remote position. Roles and Responsibilities: • Strong experience with development and writing of nonclinical documents (eg, Module 2.4 and 2.6 eCTD submission documents, Investigator’s Brochure [IB], Nonclinical Study Reports, Meeting Requests, Briefing Documents, RTQs), • Lead projects independently with minimal oversight, lead the writing (structure, content and messaging) of nonclinical documents, ensure the nonclinical package aligns with current regulatory guidelines and meets scientific integrity, • Ability to author based on highly technical sources such as GLP and non-GLP nonclinical study reports, in vivo and in vitro nonclinical data, • Ability to develop a mapping plan for the placement of nonclinical studies within structure of Module 2.4 and 2.6 eCTD submission documents, • Interpret and analyze applicable pharmacokinetics, pharmacology, and toxicology data (eg, Prism files, bioanalytical reports, clinical pathology reports, PK/TK evaluation reports), • Collaborate with cross-functional teams such as project management, safety, efficacy, biostats, regulatory operations, and CMC, • Demonstrated ability to lead others to complete complex projects, • Ability to complete documents according to sponsor’s format, processes, and according to regulatory guidelines, • Ability to effectively operate in an environment that requires negotiation, persuasion, collaboration, and analytical judgment, • Organizational expert within the nonclinical subject area, • Excellent written/oral communication and strong time and project management skills, • Ability to attend regular team meetings, lead client meeting and CRMs, • Ability to work in various client systems (eg, SharePoint, Veeva RIM, PleaseReview, EndNote), templates and toolbars, • Strong understanding of regulatory guidances as it applies to nonclinical submission documents and drug development (eg, ICH, FDA and EMA regulations and guidelines, GLP, GCP, GMP and GDP)Requirements:, • BS + in pharmacology, toxicology, biology or chemistry, or related field, with industry experience within regulatory writing, regulatory affairs, laboratory sciences, quality assurance/control, • Knowledge of GLP, ICH guidelines, and applicable regulatory requirements, • 2+ years of pharmaceutical regulatory nonclinical writing experience, • Strong writing and analytical skills, • Proficiency with MS Office applications., • Hands-on experience with clinical trial and pharmaceutical development preferred wgnsSFcAsl

< Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enhance the market's knowledge of hATTR amyloidosis. In addition, this important role will be a collaborative partner to the local strategic team that supports the account. The BAE (TTR BAE) will be principally responsible for identifying and/or targeting healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption within their assigned territory. The BAE will be responsible for achieving territory targets and other business objectives through account and customer strategies, while also partnering & collaborating very closely with internal and external stakeholders to effectively manage all aspects of the regional business. Achievement of targets will be grounded in Alnylam's core values-our unwavering commitment to people, a sense of urgency, passion for excellence, innovation and discovery, and an open culture-while upholding the highest standards of integrity. This position reports to the Regional Business Director within its respective area. Key Responsibilities • Identify and/or target healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption., • Continuously assesses sales opportunities and challenges within territory and accounts to maintain and grow their business., • Effectively prioritizes and manages time, activities, and resources to optimize access to and development of accounts with the most sales potential., • Builds and maintains relationships with physicians by maximizing their time through pre-call planning, leveraging insights to tailor a call plan, and conducting post-call analysis to continually refine and enhance their approach., • Proactively builds effective working relationships with internal/external stakeholders; can drive agreement/decisions from multiple stakeholders; can read people's emotions and flex communication style. Adjusts their approach based on different stakeholder needs, concerns, or audience member to drive alignment and meet their work goals., • Effectively communicates and closely collaborates with stakeholders across commercial, compliance, legal, market access, and patient care centers to help ensure access at site of care., • Builds individual account plans for key accounts and physicians including how to approach those customers, achieve sales goals, and maximize sales results., • Collaborates with key accounts and physicians to drive patient identification through market development and physician education; develop a territory strategy to retain customers., • Effectively utilizes resources such as programs, in-services, and in office presentations to impact territory results., • Demonstrates and upholds the highest standards of integrity and compliance., • Additional responsibilities as required to support business needs and organizational priorities. Qualifications • 4-year degree from an accredited college or university required. MBA/Science Degree preferred., • 5+ years of progressive and successful business experience in biotech or the specialty pharmaceutical industry., • Experience in Cardiology, • A successful track record of strong sales performance., • Specialty product launch experience, • Understanding of buy and bill and specialty channel distribution is preferred., • Hospital / Institution knowledge and expertise with pharmacy formulary processes., • Experience in driving, leading and delivering upon territory-level cross functional business planning and influencing without authority., • Demonstrates adherence to all company policies, industry regulations, and ethical standards, ensuring compliant business practices at all times., • Excellent communication and listening skills., • Collaboration:Builds strong relationships with internal teams, contributes insights, and independently and proactively engages cross-functional partners to solve issues., • Customer Focus:Consistently tailors brand messaging by learning customer needs and preferences while deepening product knowledge and market knowledge, • Execution:Takes ownership of territory, aligns goals with regional objectives, and develops detailed, customer-focused business plans that are continuously reviewed for impact., • Critical Thinking:Utilizes data analysis tools to identify sales trends, anticipate risks, refine strategies, and make informed decisions with growing independence., • Must be comfortable spending 60% of time traveling; some overnight travel required including travel to Boston, congresses and within large geographical territories., • Driving is an essential duty of the job; candidates must have a valid driver's license to be considered and be insurable., • Must live within assigned territory. #LI-Remote #LI-ST1 U.S. Pay Range $144,500.00 - $195,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Join us as Associate Director, Statistics in our Cambridge, MA office. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. This patient focus drives the organization to create the medicines patients need and the innovations that will deliver genuine improvements to their lives. Takeda insists on a high standard for innovation in order to deliver true value to patients, healthcare providers, payers and other stakeholders. The R&D Data and Quantitative Sciences organization influences senior leadership and stakeholders to advance Takeda’s R&D pipeline. Central to Takeda’s R&D operating model are the pillars of Data & Quantitative Sciences, which are leveraged to support the imperative of becoming a data-driven and scientifically and quantitatively disciplined rigorous organization. R&D Data & Quantitative Sciences encompasses several global functions, including Quantitative Pharmacology and Translational Sciences, Statistics & Quantitative Sciences, Programming, Patient Safety & Pharmacovigilance, and Strategic Operations The Statistics and Quantitative Sciences (SQS) department integrates data science, analytics, and quantitative methods to enhance efficiency and precision throughout the drug discovery and development lifecycle. It leverages cutting-edge technology, machine learning, AI, and statistical methods to analyze complex datasets, generate predictive models, and provide actionable insights. It collaborates cross-functionally to ensure scientific rigor and compliance with regulatory standards in all decision-making processes. Lead delivery for one or more assets at GPT level or specialty area in preclinical, clinical, translational Facilitate execution and delivery collaboration cross functionally in Global Project Teams (GPTs), generally within DQS and R&D, and with external vendors Lead and be accountable for asset level delivery strategies being implemented with effective risk identification and mitigation Must have degree in statistics/biostatistics or in other equivalent quantitative sciences along with the following specific credentials: PHD with ~ 5 years experience Scientific understanding of drug R&D to inform methodological input with product team or in a platform Ability to Identify and research new innovative approaches and leverage fit-for-purpose methods in to programs Lead and be accountable for asset level strategies being implemented Demonstrate mentorship, matrix or direct management of small team of SQS colleagues This position is currently classified as “ hybrid” in accordance with Takeda’s Hybrid and Remote Work policy. No Phone Calls or Recruiters Please. #The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. S. based employees may be eligible for short-term and/ or long-term incentives. S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Full time

< Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enhance the market's knowledge of hATTR amyloidosis. In addition, this important role will be a collaborative partner to the local strategic team that supports the account. The BAE (TTR BAE) will be principally responsible for identifying and/or targeting healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption within their assigned territory. The BAE will be responsible for achieving territory targets and other business objectives through account and customer strategies, while also partnering & collaborating very closely with internal and external stakeholders to effectively manage all aspects of the regional business. Achievement of targets will be grounded in Alnylam's core values-our unwavering commitment to people, a sense of urgency, passion for excellence, innovation and discovery, and an open culture-while upholding the highest standards of integrity. This position reports to the Regional Business Director within its respective area. Key Responsibilities • Identify and/or target healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption., • Continuously assesses sales opportunities and challenges within territory and accounts to maintain and grow their business., • Effectively prioritizes and manages time, activities, and resources to optimize access to and development of accounts with the most sales potential., • Builds and maintains relationships with physicians by maximizing their time through pre-call planning, leveraging insights to tailor a call plan, and conducting post-call analysis to continually refine and enhance their approach., • Proactively builds effective working relationships with internal/external stakeholders; can drive agreement/decisions from multiple stakeholders; can read people's emotions and flex communication style. Adjusts their approach based on different stakeholder needs, concerns, or audience member to drive alignment and meet their work goals., • Effectively communicates and closely collaborates with stakeholders across commercial, compliance, legal, market access, and patient care centers to help ensure access at site of care., • Builds individual account plans for key accounts and physicians including how to approach those customers, achieve sales goals, and maximize sales results., • Collaborates with key accounts and physicians to drive patient identification through market development and physician education; develop a territory strategy to retain customers., • Effectively utilizes resources such as programs, in-services, and in office presentations to impact territory results., • Demonstrates and upholds the highest standards of integrity and compliance., • Additional responsibilities as required to support business needs and organizational priorities. Qualifications • 4-year degree from an accredited college or university required. MBA/Science Degree preferred., • 5+ years of progressive and successful business experience in biotech or the specialty pharmaceutical industry., • Experience in Cardiology, • A successful track record of strong sales performance., • Specialty product launch experience, • Understanding of buy and bill and specialty channel distribution is preferred., • Hospital / Institution knowledge and expertise with pharmacy formulary processes., • Experience in driving, leading and delivering upon territory-level cross functional business planning and influencing without authority., • Demonstrates adherence to all company policies, industry regulations, and ethical standards, ensuring compliant business practices at all times., • Excellent communication and listening skills., • Collaboration:Builds strong relationships with internal teams, contributes insights, and independently and proactively engages cross-functional partners to solve issues., • Customer Focus:Consistently tailors brand messaging by learning customer needs and preferences while deepening product knowledge and market knowledge, • Execution:Takes ownership of territory, aligns goals with regional objectives, and develops detailed, customer-focused business plans that are continuously reviewed for impact., • Critical Thinking:Utilizes data analysis tools to identify sales trends, anticipate risks, refine strategies, and make informed decisions with growing independence., • Must be comfortable spending 60% of time traveling; some overnight travel required including travel to Boston, congresses and within large geographical territories., • Driving is an essential duty of the job; candidates must have a valid driver's license to be considered and be insurable., • Must live within assigned territory. #LI-Remote #LI-ST1 U.S. Pay Range $144,500.00 - $195,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Vice President , Global Clinical Lead - Solid Tumor in our Cambridge office. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Responsible for leading as the Global Clinical Lead a large solid tumor oncology franchise that encompass multiple late stage and early phase programs . Ensures ongoing review and agreement of the Therapy Area Strategy and associated documents formulated by the OTAU leader prior to their review and approval by appropriate governance committees. Responsible for review of synopses, other relevant clinical study documents and critical Study Results. Provide leadership and oversight of specific OTAU related programs and if applicable other indication specific clinical leads. Accountable to Oncology Clinical Science Head to provide strategic clinical input on assigned clinical studies. Consistent with the Takeda R&D Oncology Therapeutic Area Unit strategy, goals and objectives, this leader will partner with the other key functions and leaders and members of Oncology Precision and Translational Medicine, Oncology Portfolio Strategy Group, Global Regulatory Affairs, Quantitative and Clinical Pharmacology, other R&D Functional Line Oncology Therapeutic Area Leads, Global Product Launch Strategy Oncology Franchise Leads, Regional Oncology Franchise Leads, Oncology Drug Development Unit (DDU) and other Oncology extended leadership, to drive the alignment on global clinical research and development strategy as related to internal and external pipeline and non-pipeline initiatives for the Takeda R&D Oncology Community across all regions Part of the Oncology Clinical Sciences Leadership Team providing key input in strategic planning and connectivity for the overall Oncology Clinical Sciences group Leads the Global Development Team (US, EU, and others) managing both the US/EU Development Team and the Japan/ China Development team for assigned compounds. In some cases may lead the US/EU Development Team but more likely will oversee the study physician and/or clinical scientist leads responsible for leading the team. Emphasis will be on insuring that the development teams are proactively identifying contingencies, potential risks and strategies to address future obstacles. Provides continual critical evaluation of the development strategy to maintain a state-of-the-art development plan that is competitive and consistent with the latest regulatory requirements, proactive identification of challenges, and development of contingency plans to meet them. Responsible for high impact global decisions: interpreting data from ongoing internal and external studies, assessing the medical and scientific implications and making recommendations that impact regional and global development such as “go/no go” decisions or modification of development plans or study designs that may have a significant impact on timelines or product labeling. Plans clinical development strategies in context of medical/clinical significance considering how a given product will fit in with current treatments, standard of care, and unmet medical need. Primary interface with Medical Affairs team for strategy and to support of product commercial efforts Contributing to the creation and maintenance of regional KOL network Liaison with Clinical Operations and Project Management for co-ordination of logistics study planning and implementation ~ Consistent with membership of the Clinical Review Board Committee, responsible for critical review of synopses, protocols, IBs and relevant clinical documents relating to studies in assigned compounds. ~ Trial Medical Monitoring ~ Reviews and assesses overall safety information in conjunction with Pharmacovigilance and Medical Monitor of record for assigned compounds. ~ Oversees and leads all clinical science activities involved in interactions with FDA, other regulatory agencies and key opinion leaders relevant to assigned compounds. Due Diligence, Business Development and Alliance Projects Serves as clinical contact point for ongoing alliance projects and interface with partner to achieve Takeda’s strategic goals while striving to maintain good working relationship between Takeda and partner. Assigns and manages clinical science staff who are involved in many of these activities. ~ Leadership, Task Force Participation, Upper Management Accountability Works with functional leadership to prioritize projects within the therapeutic area. Hires, manages, mentors, motivates, empowers, develops and retains staff to support assigned activities. Conducts performance reviews and drive goal setting and development planning. MD or combined MD/PhD or internationally recognized equivalent with minimum 15 years pharmaceutical research experience, including minimum 10 years late phase clinical development experience with a focus on medical oncology ~ Clinical Training and Clinical Experience in Hematology/Oncology and/or Medical Oncology especially in solid tumor malignancies ~ Strong depth of scientific and clinical understanding and experience in cancer biology especially in immune based therapies. ~ Experience in conducting and/ or leading multiple clinical trials involving immune based therapies ~ Proven experience in successfully leading and supervising direct reports including several physicians, physician scientists, scientists within a clinical development team in a global matrix environment. ~ Demonstrated ability to foster a high-performance culture and build organizational capabilities. ~ Strong leadership commitment to diversity, equity and inclusion, with experience in creating an inclusive and collaborative team environment that leverages diverse perspectives. ~

Description This is an Institutional Account Manager position in a startup Pharma organization being built to launch a cardiovascular product in the critical care space. Reporting to the Syneos Health Area Business Director, the Account Manager will be responsible for engaging key stakeholders within complex hospital accounts, institutional systems and integrated delivery networks (IDNs). Responsibilities: • Maximize relationships with key academic institutions, IDNs and GPOs and leverage these relationships to generate increased demand and access for the product by targeting appropriate prescribers and decision influencers within the hospital., • Partner with health systems to influence heads of departments, service line leaders, RNs, floor directors, and hospital pharmacy to secure formulary access and pull through of product utilization in the Hospital., • Increase adoption and pull through of institutional/GPO contracts., • Partner with administrators within health systems to remove barriers to appropriate use of product., • Achieve and/or exceed targeted sales goals in an assigned territory by developing, implementing and executing an integrated territory business plan encompassing key accounts with the goal of maximizing sales., • Establish and maintain professional relationships with targeted physicians to maximize new business opportunities., • Achieve success in a complex, matrixed selling environment in which the need for collaboration and cross-functional discipline is critical. Cross-functional partners may consist of Market Access, Medical, Marketing and Operations colleagues., • Use data tools and insights, and other informational sources to determine strategies and tactics for business decision-making., • Demonstrate account-based selling skills (including group presentations, etc.). Build relationships in institutions aligned with customer segmentation., • Plan and organize activities to ensure regular and consistent coverage of the territory according to a plan of action., • Develop a complete understanding of the health care delivery system within each assigned customer, including the physician hierarchy, key pharmacy personnel, clinical nursing staff, etc., • Collaboratively build account plans with field colleagues and leadership, that will increase demand and patient care., • Develop deep product and competitor knowledge and understanding of local and regional market trends., • Manage territory budget to support sales and marketing activities., • Complete all administrative tasks in a timely manner., • Execute the company brand strategy and tactics within their assigned geographic area., • Participation in required training and development programs., • BA/BS degree required., • 5+ years pharmaceutical/biotech sales experience., • 2+ years cardiovascular sales experience in the Hospital setting is required., • Hospital/Institutional experience highly preferred., • Knowledge of formulary approval process and driving formulary approvals is preferred., • Must live within territory or within territory boundaries., • Proven track record of success in a high science competitive selling environment., • Ability to identify key decision makers, develop positive relationships and strong customer dedication., • Self-starter, highly motivated to succeed., • Strong communication, business analytics and account management skills. Why Syneos Health? Here, the work is challenging, and the pace is exhilarating. By joining one of our commercial teams, you're empowered to succeed with the support, resources, and autonomy that you need. The diversification and breadth of our new and existing partnerships create a multitude of career paths and employment opportunities. Syneos Health has launched more sales teams in the last 5 years across all major therapeutic areas than the top 25 pharma companies combined. Join our game-changing, global company dedicated to creating better, smarter, faster ways to get biopharmaceutical therapies to patients. Experience the thrill of knowing that your everyday efforts are contributing to improving patients' lives around the world. Work Here Matters Everywhere | How are you inspired to change lives? Syneos Health companies are affirmative action/equal opportunity employers (Minorities/Females/Veterans/Disabled) Syneos Health has a voluntary COVID-19 vaccination policy. We strongly encourage all employees to be fully vaccinated. Additionally, certain local governments or Syneos Health customers may have vaccine requirements that apply to some of our employees. These employees are required to submit proof of vaccination to Syneos Health and maintain compliance with these requirements. At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position will include a competitive compensation package, Health benefits to include Medical, Dental and Vision, Company match 401k, flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos Health complies with all applicable federal, state, and municipal paid sick time requirements. 400003347

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide. This role is within the Global Regulatory Affairs (GRA) Chemistry Manufacturing & Controls (CMC) and Devices organization, and will contribute to the team’s delivery of critical functions as follows: With minimal supervision, develops and leads the execution of regulatory CMC investigational, registration and/or post-approval strategies for assigned products. RA CMC member on the Global Regulatory CMC team. May serve as or act as the delegate for the GRA CMC Product Lead at Regulatory, Pharmaceutical Development, and Commercial project teams throughout clinical development and commercial lifecycle. Can apply and adapt this understanding to projects to enhance probability of regulatory success and regulatory compliance. Ability to draw from prior experience, precedents and other regulatory intelligence beyond regulations. With minimal supervision, develops, plans, executes and manages regulatory submissions per the GRA CMC Product Team technical regulatory strategy Independently defines CMC content (data and documentation) requirements for regulatory submissions and reviews this content for conformance with established requirement. With supervision, may represent Takeda RA CMC in Health Authority meetings and support CMC preparation activities for meetings with Health Authorities on CMC related matters. Interacts directly with international Health Authorities on administrative procedural topics, as required. Evaluates change proposals for global regulatory impact. As a GRA CMC member, ensures regulatory compliance with HA regulations. Ensures project team colleagues, line management, and key stakeholders are apprised of developments that may impact regulatory success, exercising sound judgement and communicating in a professional and timely manner. Reviews, provides regulatory CMC input and approves – as needed – technical protocols, reports, etc. to ensure alignment with global regulatory requirements and standards. When in a GRA CMC Product Team lead role, prepares and maintains relevant regulatory documentation (e.g., technical regulatory strategy documents, storyboards, risk assessments, etc.) and provides tactical regulatory guidance to product teams in line with global regulatory strategies. Accountable for development and / or commercial products approvals and meeting targets for projects/products within respective modalities. Supports and/ or leads assigned global regulatory submissions (e.g., Works effectively across a complex matrix environment with stakeholders to ensure effective strategies are implemented and project execution is on target. Proactively communicates CMC regulatory strategies, key issues and risks through assigned programs / products development activities and LCM in adequate and timely manner to cross-functional programs/ products teams and management level within GRA CMC, GRA, PS, GMS and QA - as appropriate. BS/BA Degree in a Scientific Discipline, Advanced Degree (M.10+ years of overall biopharmaceutical/device industry experience with 5+ years pharmaceutical Regulatory CMC or Device experience, including experience leading a major variation/amendment, supporting an initial IND/IMPD preparation, or supporting an initial NDA/BLA. Equivalent industry experience in Pharmaceutical Development, Analytical Development, Production, Quality Assurance can be considered). ~ Understanding of scientific principles and regulatory CMC requirements relevant to global drug development and post-market support. ~ Proven ability to understand and communicate regulatory strategy to drug development, registration, and post-market support teams. ~ Base regulatory strategy recommendations on precedents and other regulatory intelligence as well as regulations and guidelines. ~ Able to deal with issues of critical importance with minimal supervision. At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. This position is currently classified as hybrid following Takeda's Hybrid and Remote Work policy. #The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. S. based employees may be eligible for short-term and/ or long-term incentives. S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others.

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide. Takeda is committed to creating better health for people and a brighter future for the world. Guided by our OneOncology vision, we are advancing a rapidly growing oncology portfolio with potentially first-in-class and best-in-class therapies, including antibody-drug conjugates (ADCs), complex biologics and small molecules. Our goal is to accelerate access to transformative medicines and make a lasting impact on patients worldwide. Join Takeda as a Senior Director, Global Regulatory Lead – Oncology, where you will be part of the global regulatory team. In this influential role, you will lead a top-priority program, building cross-functional teams capable of translating complex challenges and ideas into actionable strategies. You will set global regulatory direction, provide expert guidance, and lead late-stage projects to ensure innovative and robust strategies are in place from development through registration and launch readiness for high-impact oncology programs. * Lead global regulatory strategy for assigned programs across development stages. Provide strategic, operational and tactical regulatory insight on one or multiple complex global oncology projects in clinical development with focus on innovative ways of addressing barriers to development strategies as well as accelerating access of our products to patients * Will be responsible for complex and potentially multiple projects within the Oncology TAU. Interfaces with the Global Project Team (GPT) to lead and support cross-functional company objectives. * Serve as global regulatory lead (GRL)/ Franchise global regulatory lead (GRL) on cross-functional teams for priority programs, providing strategic input and regulatory expertise. * Leads the Global Regulatory Teams (GRT) accountable for the development of innovative global strategies in line with applicable regulations to achieve business objectives for development of Oncology products. When necessary, seeks expert advice and technical support from functional stakeholders and senior management. * Acts independently under the direction of a Global Regulatory Portfolio Lead and/or TA Head. May participate in or lead regulatory and company initiatives. Based on experience and scientific strengths, expands knowledge of TA and provides coaching and mentoring for GRT members. * Ensures alignment of global regulatory strategies with Leadership Team. Presents meaningful regulatory assessments and regulatory recommendations to management. * Ensure project team colleagues, line management, and key stakeholders are apprised of developments that may impact regulatory success, exercise sound judgement and communicating in a professional and timely manner. * Accountable for US FDA submissions and approvals of project(s) of responsibility. May serve as the primary FDA point of contact for projects of responsibility. * Accountable for independently ensuring all submission types are executed on time with high quality, including major submissions (NDA/BLA/MAA) * For the project(s) of responsibility, collaborate with all Takeda regions to ensure a global regulatory strategy is created and executed upon for all projects within area of responsibility. * Partner with global market access colleagues to lead interactions with joint regulatory/health agency/HTA bodies on product specific value evidence topics, as applicable. * Develop/author and execute global regulatory strategies for complex strategies. May oversee execution. * Monitor and anticipate trends that impact both the regulatory and access environments to strengthen product development plan(s) and adopt regulatory strategies in a timely manner. * Responsible for demonstrating Takeda leadership behaviors. * May lead regulatory assessment as part of due diligence teams for licensing opportunities. * Identify and propose solutions to management for any resource gaps for assigned project(s). * BSc/BA Degree, scientific discipline strongly preferred. * Advanced degree in a scientific discipline (PharmD/PhD/MD) strongly preferred * 12+ years of pharmaceutical industry experience. This is inclusive of 10 years of regulatory experience or combination of 8+ years regulatory and/or related experience. * Experience in reviewing, authoring, or managing components of regulatory submissions including for Late-Stage assets. * Solid working knowledge of drug development process and regulatory requirements. Knowledge of FDA, EU, Canada, ROW and post-marketing a plus. * Understand and interpret complex scientific issues across multiple projects as it related to regulatory requirements and strategy. * Understands and interprets scientific data as it relates to regulatory requirements and strategy for assigned projects and provides knowledge and expertise to guide team in established and building appropriate regulatory strategy. * Strong oral and written communications, managing and adhering to timelines, negotiation skills, integrity and adaptability. * Demonstrates acceptable skills with increasing independence in the area of regulatory strategy such as understanding broad concepts within regulatory * Strong and independent skills in regulatory strategy such as understanding broad concepts within regulatory affairs and implications across the organization and globally; proactively identifies regulatory issues; offers creative solutions and strategies, including risk mitigation strategies. * Must work well with others and within global teams. * Able to bring working teams together for common objectives. * Acceptable and independent skills in the area of regulatory strategy such as understanding broad concepts within regulatory affairs and implications across the organization and globally; proactively identifies regulatory issues; offers creative solutions and strategies, including risk mitigation strategies. At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work. Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. This position is currently classified as hybrid following Takeda's Hybrid and Remote Work policy. #LI-Hybrid #LI-AA1 Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $212,000.00 - $333,190.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, <

< Overview The Strategic Account Lead (SAL) roleleads strategic engagement and contracting with target key accounts in order to drive growth, revenue, and joint value creation for Alnylam and the customer by enabling and optimizingaccess toAlnylam products and driving innovation for patients and health care providers. Key Responsibilities The Strategic Account Lead (SAL) will provide innovative, influential account engagement to shape and deliver the strategy for Alnylam Strategic Accounts in order to achieve access, create value and deliver profitable growth for Alnylam. • Lead the development and execution of the comprehensive account strategy for target accounts to bring the best of Alnylam to the customer and to maximize profitability, revenue growth and market share for Alnylam, • Analyze and synthesize information from multiple sources to identify and prioritize business opportunities across the account by applying relevant frameworks and analytical methods, • Work with the Alnylam Leadership Team to co-develop and agree on strategies, programs objectives and KPIs for target regional accounts aligned with organizational and brand priorities and the wider business strategy, • Support the account team with the prioritization of solutions, programs and specific pull-through tactics to ensure sustainable growth and mutual value creation, • Anticipate likely market and customer developments, identify third party influence factors and shape the account strategy accordingly, • Partner with target healthcare systems and organized customers to foster innovation in care through the adoption of Alnylam's products, • Engage senior level stakeholders to influence policies, decisions and perceptions to enable patients to effectively navigate the treatment journey and ensure appropriate use of Alnylam products, • Facilitate the introduction of new products and indications with institutional stakeholders by ensuring adequate budget allocation at the strategic account level, • Leverage a range of strategies and tactics to maximize the level and quality of access for Alnylam products, • Identify programs to partner with the Organized Customer to enhance the system of care and clinical decision making, • Provide insights, education and information about scientific, clinical and technological innovation, • Facilitate strategic partnership with account stakeholders to create mutual value for Alnylam and customers and deliver strategic goals, • Identify and maintain strong relationships with senior business stakeholders (Chief, VP, Director) in target accounts to support access for Alnylam's products across the company portfolio, • Strengthen the perception of Alnylam as a strategic partner by sharing insights and information to support patient identification and improving the delivery of care by establishing treatment pathways and protocols, • Provide clear direction to other field teams to identify and prioritize stakeholders within their target accounts, • Negotiate, review and agree contracts, incorporating solutions to strengthen partnerships with strategic account stakeholders, • Collaborate with other functional and business leaders to ensure adequate Voice of the Customer to inform strategic planning across all stakeholders and channels, • Support the delivery of account goals for National accounts, working closely with the Strategic Accounts Team, • Support the execution and pull through of contracting and initiatives with national organized customers to ensure value maximization, • Measure, report and communicate value delivered for national organized customers in order to strengthen customer partnership, • Share insights gathered through customer engagement Qualifications * • Bachelor's degree, emphasis in Accounting, Marketing, Business Administration or equivalent work experience in business management, ideally complemented by an MBA, • Minimum 7 years of experience in B2B selling in a life sciences environment, • Previous account management experience with health systems and/or hospitals/ IDNs, • High level of confidence and capability to understand and communicate complex scientific concepts to a range of stakeholders, plus executive presence and communication skills to engage with a C-Suite audience, • Expertise and understanding of dynamic market access value models such as value-based propositions and budget impact and cost effectiveness models, etc, • Strong interpersonal skills including written and oral communication skills, ability to synthesize data, interpret and translate into compelling and clear commercial strategies and plans, • Demonstrated ability to successfully mobilize a cross-functional team, including interpersonal skills to foster collaboration and succeed in a highly matrixed environment by leading without direct authority, • Understanding of the IDN environment, including coverage and reimbursement, pricing and contracting, formulary management and health technology assessment, • Strong analytical skills and ability to think critically, challenge conclusions and underlying assumptions, • Ability to synthesize multi-source information (qualitative and quantitative) to develop strategic plans, • Knowledge of value based healthcare and outcome based models, • Executive presence and the ability to interact and negotiate with C-suite customers, • Highly proficient in Microsoft; Excel, Word, and PowerPoint Additional Preferred Experience * • Master's degree: Master of Business Administration (MBA) preferred, • Active membership of relevant pharmaceutical associations would be beneficial #LI-ST1 #LI-Remote U.S. Pay Range $204,000.00 - $276,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide. The Senior Manager, Clinical Partner Outsourcing (CPO) ensures seamless execution of clinical studies by developing robust supplier contracts through commercial negotiations and resolving commercial and operational challenges. This role is responsible for ensuring a high level of fiscal discipline as well as enhancing cross-functional collaboration, and ensuring studies start on time, aligned to business requirements and Takeda standards and with the right commercial structures in place. Responsible for the development and finalization of study level contracts and change orders in partnership with key functions and aligned with Master Service Agreements, to ensure predictable delivery, quality and alignment to Takeda’s requirements, values and policies. Lead ballparking, contracting and commercial management of complex clinical studies, understanding study requirements and translating into robust supplier contracts across a broad category of suppliers supporting R&D activities for assigned therapeutic areas and studies Apply appropriate commercial constructs, aligned to business requirements, to enable study start, even with evolving assumptions Utilize cost models and workbooks to validate contract pricing and budget assumptions for complex agreements and develop enhancements to improve validation capabilities Manage contract amendments throughout the study lifecycle Support study teams in completing final reconciliation at study closeout Develop close collaborative working relationships with clinical operations and other key stakeholders to improve understanding and engagement Generate preliminary cost estimates to support Study Execution Teams (SET) in budget planning Collaborate with study teams to address commercial/contractual challenges, proactively identify potential issues, develop contingency plans and escalate to Clinical Partner Outsourcing/SPO leadership as necessary Escalate issues through the appropriate channels when local resolution is not achievable Drive operational support & issue resolution by supporting teams in addressing operational and performance-related supplier issues Ensure consistency between contractual agreement and operational implementation Serve as a SME and lead continuous improvement initiatives to enhance performance and efficiency, identify best practices through industry benchmarking. Ensure compliance with all applicable internal policies and procedures, regulations, support inspection readiness of all regulated activities. Lead or participate in special projects and initiatives to support the business Bachelors degree required; g MBA) or certifications (e.g PMP, CPA) preferred ~7+ years of experience in the pharmaceutical industry or clinical research environment ~ Proven experience in clinical procurement, contract management, or supplier relationship management ~ Strong knowledge of clinical trial processes and regulatory requirements ~ Experience in contract negotiations, financial analysis and budget management. ~ Familiarity with CRO and clinical outsourcing models, including financial and commercial constructs ~ Sound understanding of GCP, ICH guidelines, and clinical trial regulations ~ Strong strategic thinking and project management skills ~ This position is currently classified as “remote” by Takeda’s Hybrid and Remote Work policy. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. S. based employees may be eligible for short-term and/ or long-term incentives. S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Full time An employer who violates this law shall be subject to criminal penalties and civil liability.

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Objective / Purpose: • Defines, develops and leads global strategies to maximize global regulatory success towards achievement of program objectives for complex and/or multiple projects., • Provides strategic and tactical advice to teams to achieve timely and efficient development and maintenance of programs, while ensuring compliance with applicable regulatory requirements., • Is a leader both in the department and within R&D, contributing to cross-functional initiatives and influencing the field as applicable., • Provides leadership and development for direct reports, including those that serve as global regulatory leads responsible for the design and execution of global regulatory strategies in collaboration with their regional counterparts. Accountabilities: • The Director will be responsible for complex or highly complex or multiple projects. Leads the Global Regulatory Teams (GRTs) and applicable sub-working groups, such as the Label Working Group, and represents GRTs at project team meetings. Defines strategies and provides tactical guidance to teams and collaborates cross-functionally to ensure the global regulatory strategy is updated and executed, ensuring global regulatory compliance and/or oversees direct reports or junior staff responsible., • Ensures global regulatory strategies defined within the GRT are effectively implemented and maintained in line with changing regulatory and business needs and anticipates such changes to lead adaptations to regulatory strategy., • Ensures project team colleagues, line management, and key stakeholders are apprised of developments that may impact regulatory success, exercising sound judgement and communicating in a professional and timely manner., • Proactively anticipates risks and responsible for developing solutions to identified risks and discussing with team and management; understands probabilities of technical success for the solutions., • Accountable for all US FDA submissions and approvals of project(s) of responsibility or oversees direct reports responsible. The Director will lead all submission types., • Accountable for building global regulatory strategies as defined within the GRT and ensure those are effectively implemented and maintained in line with changing regulatory and business needs., • Direct point of contact with health authorities, leads and manages FDA meetings. Manages direct reports or junior staff as needed., • Accountable for working with regulatory regional leads, other functions and vendors to ensure global regulatory submissions are provided to local Takeda affiliates in compliance with local regulations and to maintain compliance for products., • Oversee vendor responsibility for regulatory activities and submissions related to projects within scope., • Participates with influence in or leads departmental and cross-functional task-forces and initiatives., • Lead regulatory reviewer in due diligence for licensing opportunities., • Partner with global market access colleagues to Lead interactions with joint regulatory/health agency/HTA bodies on product specific value evidence topics, as applicable., • Monitor and anticipate trends that impact both the regulatory and access environments to strengthen product development plan(s) and adopt regulatory strategies in a timely manner., • Responsible for demonstrating Takeda leadership behaviors. Education & Competencies: • Bachelor’s Degree, scientific discipline strongly preferred, • Advanced degree in a scientific discipline (PharmD/PhD/MD) strongly preferred, • 8+ years of pharmaceutical industry experience. This is inclusive of 6 years of regulatory experience or combination of 4+ years regulatory and/or related experience., • Preferred experience in reviewing, authoring, or managing components of regulatory submissions., • Solid working knowledge of drug development process and regulatory requirements. Knowledge of FDA, EU, Canada, ROW and post-marketing a plus., • Understand and interpret complex scientific issues across multiple projects as it relates to regulatory requirements and strategy., • Understands and interprets scientific data as it relates to regulatory requirements and strategy for assigned projects and provides knowledge and expertise to guide team in established and building appropriate regulatory strategy., • Strong oral and written communications, managing and adhering to timelines, negotiation skills, integrity and adaptability., • Demonstrates strong skills with increasing independence in the area of regulatory strategy such as understanding broad concepts within regulatory affairs and implications across the organization and globally; proactively identifies regulatory issues; offers creative solutions and strategies, including risk mitigation strategies., • Must work well with others and within global teams., • Able to bring working teams together for common objectives., • Acceptable and independent skills in the area of regulatory strategy such as understanding broad concepts within regulatory affairs and implications across the organization and globally; proactively identifies regulatory issues; offers creative solutions and strategies, including risk mitigation strategies. This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy. Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $177,000.00 - $278,080.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Boston, MA Employee Regular Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide. This role is within the Global Regulatory Affairs (GRA) Chemistry Manufacturing & Controls (CMC) and Devices organization, and will contribute to the team’s delivery of critical functions as follows: With minimal supervision, develops and leads the execution of regulatory CMC investigational, registration and/or post-approval strategies for assigned products. RA CMC member on the Global Regulatory CMC team. May serve as or act as the delegate for the GRA CMC Product Lead at Regulatory, Pharmaceutical Development, and Commercial project teams throughout clinical development and commercial lifecycle. Can apply and adapt this understanding to projects to enhance probability of regulatory success and regulatory compliance. Ability to draw from prior experience, precedents and other regulatory intelligence beyond regulations. With minimal supervision, develops, plans, executes and manages regulatory submissions per the GRA CMC Product Team technical regulatory strategy Independently defines CMC content (data and documentation) requirements for regulatory submissions and reviews this content for conformance with established requirement. With supervision, may represent Takeda RA CMC in Health Authority meetings and support CMC preparation activities for meetings with Health Authorities on CMC related matters. Interacts directly with international Health Authorities on administrative procedural topics, as required. Evaluates change proposals for global regulatory impact. As a GRA CMC member, ensures regulatory compliance with HA regulations. Ensures project team colleagues, line management, and key stakeholders are apprised of developments that may impact regulatory success, exercising sound judgement and communicating in a professional and timely manner. Reviews, provides regulatory CMC input and approves – as needed – technical protocols, reports, etc. to ensure alignment with global regulatory requirements and standards. When in a GRA CMC Product Team lead role, prepares and maintains relevant regulatory documentation (e.g., technical regulatory strategy documents, storyboards, risk assessments, etc.) and provides tactical regulatory guidance to product teams in line with global regulatory strategies. Accountable for development and / or commercial products approvals and meeting targets for projects/products within respective modalities. Supports and/ or leads assigned global regulatory submissions (e.g., Works effectively across a complex matrix environment with stakeholders to ensure effective strategies are implemented and project execution is on target. Proactively communicates CMC regulatory strategies, key issues and risks through assigned programs / products development activities and LCM in adequate and timely manner to cross-functional programs/ products teams and management level within GRA CMC, GRA, PS, GMS and QA - as appropriate. BS/BA Degree in a Scientific Discipline, Advanced Degree (M.10+ years of overall biopharmaceutical/device industry experience with 5+ years pharmaceutical Regulatory CMC or Device experience, including experience leading a major variation/amendment, supporting an initial IND/IMPD preparation, or supporting an initial NDA/BLA. Equivalent industry experience in Pharmaceutical Development, Analytical Development, Production, Quality Assurance can be considered). ~ Understanding of scientific principles and regulatory CMC requirements relevant to global drug development and post-market support. ~ Proven ability to understand and communicate regulatory strategy to drug development, registration, and post-market support teams. ~ Base regulatory strategy recommendations on precedents and other regulatory intelligence as well as regulations and guidelines. ~ Able to deal with issues of critical importance with minimal supervision. At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. This position is currently classified as hybrid following Takeda's Hybrid and Remote Work policy. #The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. S. based employees may be eligible for short-term and/ or long-term incentives. S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others.

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Defines, develops and leads global strategies to maximize global regulatory success towards achievement of program objectives for complex and/or multiple projects. Provides strategic and tactical advice to teams to achieve timely and efficient development and maintenance of programs, while ensuring compliance with applicable regulatory requirements. Is a leader both in the department and within R&D, contributing to cross-functional initiatives and influencing the field as applicable. Provides leadership and development for direct reports, including those that serve as global regulatory leads responsible for the design and execution of global regulatory strategies in collaboration with their regional counterparts. The Associate Director will be responsible for complex or highly complex or multiple projects. Leads the Global Regulatory Teams (GRTs) and applicable sub-working groups, such as the Label Working Group, and represents GRTs at project team meetings. Defines strategies and provides tactical guidance to teams and collaborates cross-functionally to ensure the global regulatory strategy is updated and executed, ensuring global regulatory compliance and/or oversees direct reports or junior staff responsible. Ensures global regulatory strategies defined within the GRT are effectively implemented and maintained in line with changing regulatory and business needs and anticipates such changes to lead adaptations to regulatory strategy. Ensures project team colleagues, line management, and key stakeholders are apprised of developments that may impact regulatory success, exercising sound judgement and communicating in a professional and timely manner. Proactively anticipates risks and responsible for developing solutions to identified risks and discussing with team and management; Accountable for all US FDA submissions and approvals of project(s) of responsibility or oversees direct reports responsible. Accountable for building global regulatory strategies as defined within the GRT and ensure those are effectively implemented and maintained in line with changing regulatory and business needs. Accountable for working with regulatory regional leads, other functions and vendors to ensure global regulatory submissions are provided to local Takeda affiliates in compliance with local regulations and to maintain compliance for products. Oversee vendor responsibility for regulatory activities and submissions related to projects within scope. Lead regulatory reviewer in due diligence for licensing opportunities. Partner with global market access colleagues to Lead interactions with joint regulatory/health agency/HTA bodies on product specific value evidence topics, as applicable. Monitor and anticipate trends that impact both the regulatory and access environments to strengthen product development plan(s) and adopt regulatory strategies in a timely manner. Bachelor’s Degree, scientific discipline strongly preferred ~ Advanced degree in a scientific discipline (PharmD/PhD/MD) strongly preferred ~6+ years of pharmaceutical industry experience. This is inclusive of 4+ years of regulatory experience ~ Preferred experience in reviewing, authoring, or managing components of regulatory submissions. ~ Solid working knowledge of drug development process and regulatory requirements. Understand and interpret complex scientific issues across multiple projects as it relates to regulatory requirements and strategy. ~ Understands and interprets scientific data as it relates to regulatory requirements and strategy for assigned projects and provides knowledge and expertise to guide team in established and building appropriate regulatory strategy. ~ Demonstrates strong skills with increasing independence in the area of regulatory strategy such as understanding broad concepts within regulatory affairs and implications across the organization and globally; proactively identifies regulatory issues; offers creative solutions and strategies, including risk mitigation strategies. ~ Acceptable and independent skills in the area of regulatory strategy such as understanding broad concepts within regulatory affairs and implications across the organization and globally; proactively identifies regulatory issues; offers creative solutions and strategies, including risk mitigation strategies. This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. S. based employees may be eligible for short-term and/ or long-term incentives. S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Full time An employer who violates this law shall be subject to criminal penalties and civil liability.

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide. Objective / Purpose: The GI-Drug Discovery Unit at Takeda is a team of experienced, innovative and collaborative drug discovery scientists building an industry-leading portfolio of drugs for inflammatory and GI diseases with high unmet medical need. We are seeking a leader with significant experience in building and leading biology and cross-functional drug discovery teams to establish a new group focused on chronic autoimmune diseases. The Director Inflammatory Drug Discovery • Will be responsible for developing industry-leading therapeutics for patients with inflammatory diseases by leading a research group focused on drug development from target identification through to candidate selection., • Will recruit, retain, and develop a large team of world class, highly innovative in vitro and in vivo research biologists focused on understanding the molecular, cellular and organ-level drivers of inflammatory disease processes, and identifying and developing drug candidates., • Will be scientific research thought leader within the Drug Discovery Unit (DDU), working within a highly matrixed environment to build an industry-leading preclinical and early clinical therapeutic pipeline for Inflammatory Diseases., • Will set the discovery portfolio goals for high priority autoimmune diseases and ensure alignment with key stakeholders in inflammatory disease research, the clinical development team, and other Takeda stakeholders., • Will be accountable for defining the preclinical elements of multiple drug discovery programs, in partnership with other research leaders across Takeda and the early clinical development team within the GI and Inflammation Therapeutic Area., • Will interface with the business development group to identify strategically important innovative external opportunities, • Will help maintain the Takeda culture that promotes creativity, open communication, collaboration, collegiality, and a high sense of urgency. Maintain the highest quality of scientific foundations of the company’s drug discovery process. Accountabilities: Describe the primary duties and responsibilities of the job. Include only the essential functions of the job. Approximately 5 – 10 bulleted task statements should be identified. • Forms a strong partnership with clinical and commercial team colleagues for disease area strategic alignment and is accountability for formulation and delivery of mid-long term innovative strategies to build a sustainable and innovative Inflammation disease area pipeline, • The Director Inflammation Drug Discovery will lead a team of researchers in early target discovery through candidate selection and partner with the therapeutic area Translational team in the development and delivery of robust early development plans supporting programs through early clinical proof-of-concept., • The appointee will partner with the Center for External Innovation at Takeda for the identification and assessment of external platform and pipeline opportunities and be accountable for due diligence evaluation and recommendations on external opportunities in Inflammation diseases., • Is seen as an international subject matter expert and identified as a global Takeda thought leader in the field of Inflammatory disease research and keeps up up-to-date with scientific, drug discovery and development and the external competitive environment., • Represents Takeda and fosters a presence in the global inflammation and immunology scientific community through scientific meetings., • Ensures and encourages diversity and supports individual colleagues and their reports in career development., • Ensure that all Inflammation disease area Global Product Teams are resourced for optimal scientific support for research studies, mechanistic understanding, disease area evolution and competitive landscape understanding., • Creative, collaborative, proactive and confident individual with proven leadership qualities, as demonstrated by performance., • Demonstrated ability to work across functions, regions and cultures and adheres to Takeda’s values, • Excellent communicator, able to persuasively convey both ideas and data, orally, in presentation and written format, • Proven skills as an effective team player who can engender credibility and confidence within and outside the company, • Ability to distil complex issues and ideas down to simple comprehensible terms, • Demonstrates leadership presence and confidence, • Embraces and demonstrates a diversity and inclusion mindset and role models these behaviors for the organization, • Builds teams across functions and geographies with individuals who have the right skills and experience to deliver on key organizational initiatives., • Invests time in helping others to enhance their skills and perform at a higher level., • Effectively navigates the dynamics of external and internal environments and leads others by creating and inspiring and engaging workplace., • Cultivates a broad network of relationships throughout Takeda, with affiliates and external partners, • Effectively represents function in negotiations with the ability to resolve conflict in a constructive manner., • Creative scientific thinker with excellent understanding of emerging technologies that enhance disease understanding and human-focused drug development programs, • Identifies opportunities and anticipates changes in the business landscape through an understanding and ongoing assessment of the disease area-specific competitive landscape, • Forward thinking with the ability to recommend, influence and implement organizational change and continuous innovation., • Ability to take risks implementing innovative solutions, accelerating time to market., • Comfortable challenging the status quo and bringing forward innovative solutions., • Role models respect and inclusion, creating a culture that fosters innovation. Education & Competencies (Technical and Behavioral): • PhD degree in Immunology or a closely related discipline with 10+ years drug development experience in highly competitive biopharmaceutical companies, • or MS with 16+ years experience, or BS with 18+ years experience, • Expert scientific knowledge in autoimmune and inflammatory disease research with experience in lymphocyte biology is highly desired, • Highly experienced in exploratory drug development with proven biopharmaceutical industry experience leading innovative therapeutic programs and with expertise in small molecule and/or biologics drug development, • 10 years of direct line management and cross-functional project leadership experience required, • Highly knowledgeable and experienced in all aspects of Inflammation Disease drug discovery through to candidate selection/IND, including contributing to regulatory documentation., • Shows cross-cultural understanding to utilize the diverse talents and has demonstrated ability to manage matrix teams to maximize the organizational productivity., • Has strong leadership skills and acumen., • Has excellent written and verbal communication skills in English., • Capable of leading a matrixed team comprised of scientists from within Takeda as well as external collaborators., • Has significant experience of participation in BD diligence activities in the preclinical discovery function ADDITIONAL INFORMATION * The position will be based in Cambridge, MA . This position is currently classified as “hybrid” by Tak]]>

< Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enhance the market's knowledge of hATTR amyloidosis. In addition, this important role will be a collaborative partner to the local strategic team that supports the account. The BAE (TTR BAE) will be principally responsible for identifying and/or targeting healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption within their assigned territory. The BAE will be responsible for achieving territory targets and other business objectives through account and customer strategies, while also partnering & collaborating very closely with internal and external stakeholders to effectively manage all aspects of the regional business. Achievement of targets will be grounded in Alnylam's core values-our unwavering commitment to people, a sense of urgency, passion for excellence, innovation and discovery, and an open culture-while upholding the highest standards of integrity. This position reports to the Regional Business Director within its respective area. Key Responsibilities • Identify and/or target healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption., • Continuously assesses sales opportunities and challenges within territory and accounts to maintain and grow their business., • Effectively prioritizes and manages time, activities, and resources to optimize access to and development of accounts with the most sales potential., • Builds and maintains relationships with physicians by maximizing their time through pre-call planning, leveraging insights to tailor a call plan, and conducting post-call analysis to continually refine and enhance their approach., • Proactively builds effective working relationships with internal/external stakeholders; can drive agreement/decisions from multiple stakeholders; can read people's emotions and flex communication style. Adjusts their approach based on different stakeholder needs, concerns, or audience member to drive alignment and meet their work goals., • Effectively communicates and closely collaborates with stakeholders across commercial, compliance, legal, market access, and patient care centers to help ensure access at site of care., • Builds individual account plans for key accounts and physicians including how to approach those customers, achieve sales goals, and maximize sales results., • Collaborates with key accounts and physicians to drive patient identification through market development and physician education; develop a territory strategy to retain customers., • Effectively utilizes resources such as programs, in-services, and in office presentations to impact territory results., • Demonstrates and upholds the highest standards of integrity and compliance., • Additional responsibilities as required to support business needs and organizational priorities. Qualifications • 4-year degree from an accredited college or university required. MBA/Science Degree preferred., • 5+ years of progressive and successful business experience in biotech or the specialty pharmaceutical industry., • Experience in Cardiology, • A successful track record of strong sales performance., • Specialty product launch experience, • Understanding of buy and bill and specialty channel distribution is preferred., • Hospital / Institution knowledge and expertise with pharmacy formulary processes., • Experience in driving, leading and delivering upon territory-level cross functional business planning and influencing without authority., • Demonstrates adherence to all company policies, industry regulations, and ethical standards, ensuring compliant business practices at all times., • Excellent communication and listening skills., • Collaboration:Builds strong relationships with internal teams, contributes insights, and independently and proactively engages cross-functional partners to solve issues., • Customer Focus:Consistently tailors brand messaging by learning customer needs and preferences while deepening product knowledge and market knowledge, • Execution:Takes ownership of territory, aligns goals with regional objectives, and develops detailed, customer-focused business plans that are continuously reviewed for impact., • Critical Thinking:Utilizes data analysis tools to identify sales trends, anticipate risks, refine strategies, and make informed decisions with growing independence., • Must be comfortable spending 60% of time traveling; some overnight travel required including travel to Boston, congresses and within large geographical territories., • Driving is an essential duty of the job; candidates must have a valid driver's license to be considered and be insurable., • Must live within assigned territory. #LI-Remote #LI-ST1 U.S. Pay Range $144,500.00 - $195,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

< Overview: We are seeking a Director, Field Reimbursement Lead - East to manage a regional team of field reimbursement directors. The Field Reimbursement Team is a critical component of the commercial strategy and will work in close collaboration with Sales, Patient Services, Strategic Account Management and Market Access to support Alnylam's patient-focused vision of harnessing a revolution in biology for human health. This field-based position will report to the Senior Director, Field Reimbursement and requires 50-75% travel. The successful candidate must be passionate about science and deeply motivated by the quest of delivering value to patients with the long-term success of the company in mind. This individual will have a deep and board understanding of access and reimbursement across the healthcare landscape, as well as cross-functional business knowledge to optimize access and deliver an excellent customer experience. Key Responsibilities: • Hire, lead, and empower an experienced and talented team of field reimbursement directors skilled in access, coverage, and reimbursement across all sites of care including physician office, ambulatory infusion center, hospital outpatient department and home treatment, • Foster and inspire a collaborative, inclusive and high-performing team culture that encourages accountability and embraces innovation with a purposeful sense of urgency, • Provide regular performance feedback, coaching and professional development to team members, • Partner with the Senior Director, Field Reimbursement in the development of strategy, tactics and messaging that align to Market Access priorities as well as in the creation of key performance metrics, • Utilize analytics and reporting dashboards to identify access and reimbursement issues within the region and collaborate closely with leadership from Sales, Patient Services, Strategic Account Management, and Market Access in the development of strategic solutions and action plans, • Deliver consistent guidance via team calls, field ride alongs, and meeting engagements to ensure the team is compliantly and effectively leveraging tools and materials to educate healthcare professionals, • Serve as the escalation point for regional access and reimbursement challenges, • Maintain strategic relationships with Medicare Administrative Contractors (MACs) within the region to ensure optimal coverage for Alnylam therapies and monitor Local Coverage Determinations (LCDs) and National Coverage Determinations (NCDs), • Ensure team's compliance with the appropriate ways of working across diverse cross-functional partnerships Qualifications: • Bachelor's degree required, • 10+ years of pharmaceutical/biotech experience required, • 8+ years of field reimbursement experience within a 'buy and bill' environment required, • 3+ years of leading a field reimbursement team or experience managing a field- based team preferred, • In-depth knowledge of both medical benefit and pharmacy benefit across all payer types (Medicare, Medicaid, commercial and VA/DoD) and sites of care (physician office, ambulatory infusion center, hospital outpatient department and home treatment), • Established relationships with Medicare Administrative Contractors (MACs) highly preferred, • Proven ability to identify key access and reimbursement barriers to treatment and design effective resolution plans, • Demonstrated ability to work in a highly collaborative matrix, • Desire to work in a fast-paced, energetic environment, • Self-starter who is enthusiastic about rare disease and Alnylam's core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, • Must reside in or live in close proximity to designated area of responsibility #LI-ST1 #LI-Remote U.S. Pay Range $204,000.00 - $276,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: ___ AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Defines, develops and leads global strategies to maximize global regulatory success towards achievement of program objectives for complex and/or multiple projects. Provides strategic and tactical advice to teams to achieve timely and efficient development and maintenance of programs, while ensuring compliance with applicable regulatory requirements. Is a leader both in the department and within R&D, contributing to cross-functional initiatives and influencing the field as applicable. Provides leadership and development for direct reports, including those that serve as global regulatory leads responsible for the design and execution of global regulatory strategies in collaboration with their regional counterparts. The Director will be responsible for complex or highly complex or multiple projects. Leads the Global Regulatory Teams (GRTs) and applicable sub-working groups, such as the Label Working Group, and represents GRTs at project team meetings. Defines strategies and provides tactical guidance to teams and collaborates cross-functionally to ensure the global regulatory strategy is updated and executed, ensuring global regulatory compliance and/or oversees direct reports or junior staff responsible. Ensures global regulatory strategies defined within the GRT are effectively implemented and maintained in line with changing regulatory and business needs and anticipates such changes to lead adaptations to regulatory strategy. Ensures project team colleagues, line management, and key stakeholders are apprised of developments that may impact regulatory success, exercising sound judgement and communicating in a professional and timely manner. Proactively anticipates risks and responsible for developing solutions to identified risks and discussing with team and management; Accountable for all US FDA submissions and approvals of project(s) of responsibility or oversees direct reports responsible. The Director will lead all submission types. Accountable for building global regulatory strategies as defined within the GRT and ensure those are effectively implemented and maintained in line with changing regulatory and business needs. Direct point of contact with health authorities, leads and manages FDA meetings. Manages direct reports or junior staff as needed. Accountable for working with regulatory regional leads, other functions and vendors to ensure global regulatory submissions are provided to local Takeda affiliates in compliance with local regulations and to maintain compliance for products. Oversee vendor responsibility for regulatory activities and submissions related to projects within scope. Lead regulatory reviewer in due diligence for licensing opportunities. Partner with global market access colleagues to Lead interactions with joint regulatory/health agency/HTA bodies on product specific value evidence topics, as applicable. Monitor and anticipate trends that impact both the regulatory and access environments to strengthen product development plan(s) and adopt regulatory strategies in a timely manner. Bachelor’s Degree, scientific discipline strongly preferred ~ Advanced degree in a scientific discipline (PharmD/PhD/MD) strongly preferred ~8+ years of pharmaceutical industry experience. This is inclusive of 6 years of regulatory experience or combination of 4+ years regulatory and/or related experience. ~ Preferred experience in reviewing, authoring, or managing components of regulatory submissions. ~ Solid working knowledge of drug development process and regulatory requirements. Understand and interpret complex scientific issues across multiple projects as it relates to regulatory requirements and strategy. ~ Understands and interprets scientific data as it relates to regulatory requirements and strategy for assigned projects and provides knowledge and expertise to guide team in established and building appropriate regulatory strategy. ~ Strong oral and written communications, managing and adhering to timelines, negotiation skills, integrity and adaptability. ~ Demonstrates strong skills with increasing independence in the area of regulatory strategy such as understanding broad concepts within regulatory affairs and implications across the organization and globally; proactively identifies regulatory issues; offers creative solutions and strategies, including risk mitigation strategies. ~ Acceptable and independent skills in the area of regulatory strategy such as understanding broad concepts within regulatory affairs and implications across the organization and globally; proactively identifies regulatory issues; offers creative solutions and strategies, including risk mitigation strategies. This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. S. based employees may be eligible for short-term and/ or long-term incentives. S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Full time An employer who violates this law shall be subject to criminal penalties and civil liability.

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Purpose * Leveraging a proven track record of leading at least 3 discovery programs to clinic, The Global Therapeutic Research Lead (G-TRL) is a pipeline critical strategic leader responsible for driving Research projects to the clinic. The individual will sit on the Neuroscience Drug Discovery Unit (NS DDU) Leadership Team. * Leader for at least one or more of Takeda’s top priority small molecule projects with substantial clinical and commercial potential with a clear accelerated path to the clinic. * You will provide mentorship to team members to elevate enterprise thinking and capabilities of our drug discovery talent across the global Research function. * As project lead, the G-TRL builds a connected view of the project within the Neuroscience TA strategy and treatment paradigm and can represent all core expertise at depth and align with stakeholders and sponsors across the organization including Research, Clinical Development and Commercial stakeholders and executive level governance committees. * G-TRLs are responsible for creating the medicine vision, early asset strategy and managing multiple external partnerships that accelerate delivery of the project. * G-TRLs will establish smart, fast, and critical path minded practices for groups, including integrating new strategies and competitive industry ways of working. * G-TRL will advise on the continuous infusion of new Research projects aligned to strategy to generate a sustainable Research Engine generating a steady flow of high-quality INDs every year. Accountabilities * Lead and manage one or more ‘Top 10’ drug discovery molecule projects, overseeing the entire drug discovery process from target identification to preclinical development. (Top 10 projects are well validated targets that are focused on strategically aligned modalities with substantial clinical and commercial potential) * Responsible for the articulation and ownership of the project strategy, developed in partnership with internal stakeholders. * Contribute to strategy for future portfolio investment, particularly within the Inflammation and Immunology area including advising on which projects should be Top 10 projects. * Evaluate and prioritize potential drug candidates based on scientific, medical, and commercial considerations. * Represent all core expertise for project. * Partner with Clinical and Translational teams to refine asset strategy. * Ensure alignment to the therapeutic area strategy (i.e., Clinical Development). * Understand and align with commercial team for asset commercial value within the Neuroscience Therapeutic Area (NS TA). * Provide guidance and mentorship to global project team members, stimulating enterprise thinking and fostering their professional growth and development. * Mentor future and more junior project leads and elevate drug discovery capability across Research. * Collaborate with cross-functional teams and partners (e.g., DMPK, Pharmaceutical Sciences) within and outside Takeda to drive project delivery. * Pipeline and enterprise impact through effective partnering with multiple internal and external collaborators. * Provide strategic, process, and operational leadership for successful Top 10 Project delivery. * Foster a culture of innovation and scientific excellence within the matrixed drug discovery team, promoting collaboration, knowledge sharing, and continuous learning. * Become a world leading scientific expert in the projects you lead. * Oversee the design and execution of experiments, data analysis, and interpretation to enable decision-making and optimize drug discovery efforts. * Stay abreast of the latest advancements in drug discovery, emerging technologies, and industry trends, applying this knowledge to enhance drug discovery strategies. * Build and maintain relationships with key stakeholders, including academic institutions, research organizations, and industry partners inclusive of serving on joint external governance committees across the globe. * Represent Takeda externally for the Neuroscience Drug Discovery Unit and play a key role in evaluating external opportunities, serving as an effective ambassador for Takeda’s global business development brand. Education & Competencies (Technical and Behavioral): * Advanced degree in health or life sciences (e.g., Ph.D., M.D., D.V.M.) * Expected to have at least 10-12 years industry and relevant subject matter expertise within Immunology and Inflammation and at least 10-12 years global management experience, including working effectively with matrix teams. * Extensive experience in leading drug discovery teams and managing drug discovery/development projects, preferably in a pharmaceutical or biotechnology setting covering gastroenterology and inflammation. * Deep understanding of the drug discovery process, including target identification, hit-to-lead optimization, and preclinical development, anticipating, and removing roadblocks. * Proven track record of leading numerous projects, ideally 5+ projects, across discovery from target inception to Candidate Nomination or beyond. * Played a major role in 3+ INDs. * Has delivered clinical development assets in small molecules and have insight into oligonucleotide and biologic modalities * Excellent and inclusive leadership with the ability to inspire and motivate diverse teams towards achieving ambitious goals. * Reputation as a proactive, solutions-oriented leader who engages relevant expertise no matter where it resides. * Strong business acumen and understanding of the pharmaceutical industry, including regulatory requirements and commercial considerations with relevant knowledge and expertise for specific modalities. * Exceptional communication and presentation skills, with the ability to effectively communicate complex scientific concepts to diverse audiences. * Proven ability to build and maintain collaborative relationships with internal and external stakeholders across a matrixed organization. * Strong problem-solving and decision-making abilities, with a focus on data-driven decision making. * Demonstrated success in building and managing strategic partnerships with academic institutions, research organizations, and industry collaborators. * As part of our global R&D strategy, and unique to the Research organization’s strong lab presence in Shonan, Japan, this role may include the opportunity for a temporary or long-term international assignment in Japan, subject to business needs and final candidate selection. Candidates interested in global exposure are encouraged to apply. This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $238,000.00 - $374,000.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement <