Les 68 meilleures offres d'emploi : en tant que investigator, , à Royaume-Uni (avril 2026)

Operations Manager

il y a 12 heures

£30000–£45000 par an

Temps plein

Nine Elms, London

Operations Manager — Produce Network We supply fresh produce to some of London's best restaurants. While most of the city sleeps, our team is at wholesale markets hand-picking produce that lands in restaurant kitchens before breakfast service. It's fast, physical, and relentless — and right now we're a team of 3 doing the work of 10. We need the fourth. This role in one paragraph You'll run the operational engine of a growing wholesale business. Client calls, order coordination, daily reconciliation, bookkeeping, problem-solving, phone ringing — all of it is yours. You're the first person clients speak to and the last person to check that yesterday's numbers add up. If something goes wrong overnight — a wrong delivery, a short order, a supplier issue — you're the one who finds out, fixes it, and makes sure the client knows before they have to chase us. You own the daytime operation the way our Night Operations Manager owns the night. Between the two of you, the business runs 24 hours. What you'll actually do every day You're the client's main contact. Orders come in via WhatsApp, phone, and email. You process them, confirm them, flag anything unusual. When a chef calls at 8:15 AM asking where their herbs are, you already know the answer because you've read the night report and checked the dispatch log. You don't wait for problems to come to you — you call the client before they call you. That's the difference between an assistant and an operator. You coordinate the fix when things go wrong. Produce wholesale is not a clean business. Items get substituted, deliveries run late, a crate arrives damaged. When it happens, you own the resolution: investigate, coordinate with the night team or drivers, arrange the fix (re-delivery, credit note, replacement), close the loop with the client, and log the whole thing. If the same problem shows up three times, you're the person who flags it as a process issue — not just an incident. You reconcile everything, every day. What was ordered vs what was received from suppliers vs what was dispatched vs what was invoiced. Purchase orders matched against supplier invoices. Sales orders matched against customer invoices. Inventory tracked. Shortages flagged before they become emergencies. You produce a daily summary the founder reviews in 5 minutes — clean, accurate, no surprises. If you're the kind of person who finds satisfaction in numbers that balance, this will be your favourite part of the job. You run the books. Day-to-day bookkeeping in QuickBooks or Xero: bank feeds, invoices, bills, categorisation. Debtor chasing — politely on the due date, firmly at 3 days overdue, escalated to the founder at 30 days. Weekly financial summary. Monthly close support. You maintain the product cost data that powers margin tracking — weekly updates, no exceptions. The founder makes pricing and growth decisions based on numbers you produce. They have to be right. You own the phone. The main business line rings and you answer it. Existing clients with questions, prospective clients with enquiries, suppliers with updates. You're professional, you're warm, you handle what you can and route what you can't. For new enquiries, you capture the details, qualify the lead, and hand it to the founder. You support outbound sales — managing the email pipeline, scheduling meetings, preparing documents. When a new account closes, you run the onboarding playbook. Who we're looking for — honestly We're not looking for a CV. We're looking for a specific type of person. You're the person who walks into a room and notices what's broken before anyone tells you. You fix things that aren't your job because leaving them broken bothers you. You write things down because you know you'll forget otherwise. You don't need to be chased — you chase other people. When something goes wrong, your instinct is to understand why, not to find someone to blame. You're comfortable saying "I don't know, but I'll find out" and then actually finding out. You're comfortable making a decision with 80% of the information because waiting for 100% means the client is already unhappy. You're comfortable being wrong sometimes, because you know that the person who never makes a mistake is the person who never does anything. You probably have some experience in operations, admin, or office management — ideally at a small business where you wore multiple hats. Maybe you've worked in food, hospitality, or wholesale. Maybe you haven't, but you've run the back end of something and you know what it feels like when everything depends on you not dropping the ball. Essential: Strong written and spoken English · comfortable with numbers, spreadsheets, and accounting tools · self-directed (you manage yourself, we don't manage you) · able to hold 5 priorities at once without losing any · honest about mistakes · quick to learn new software (Airtable, QuickBooks/Xero, Lemlist) · right to work in the UK. Preferred: Bookkeeping experience or QuickBooks/Xero familiarity · food, hospitality, or wholesale background · complaint handling or fast-paced customer service experience · inventory or stock management exposure. Nice to have: AAT qualification · Airtable or CRM experience · knowledge of the London restaurant scene. Why this job is worth your time Most operations roles are dead ends. This one isn't. Here's why. We're a team of 3, growing fast. The person who takes this role will — within months, not years — understand every part of how a wholesale business works: client management, supply chain, financial control, inventory, sales. That's not because we'll send you on a training course. It's because you'll be doing all of it, every day, from week one. The explicit deal: start at £33k. Hit your 3-month performance review targets and move to £38k. Hit your 12-month targets and move to £45k. These aren't vague promises — they're structured milestones tied to specific outcomes we'll agree together in your first week. The long-term path is Chief Operating Officer. That's not a title we're dangling to attract applicants — it's a gap that actually exists in the business and needs to be filled by someone who's earned it from the inside. The founder wants to focus on growth and strategy. The person who proves they can run the day-to-day operation — and then improve it — becomes the person who runs it permanently. The full picture • Hours: 8 AM – 6 PM, Monday to Friday, • Location: London (on-site, not remote — the work requires being where the operation is), • Salary: £33,000 → £38,000 at 3 months → £45,000 at 12 months, all performance-linked, • Title progression: Operations Manager → Head of Operations → COO, • Team: you'll be the 4th person in a tight, high-trust team, • Culture: direct, honest, fast. We tell each other when things are wrong and we fix them together. No politics, no layers, no waiting for permission

Medical Director, Medical Safety

il y a 14 jours

London

If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description: The Global Safety Physician serves as the safety expert accountable for the global safety strategy and overall safety profile for Jazz Pharmaceuticals product/s (investigational and marketed) throughout their lifecycle. This includes supporting major pre- and post-marketing safety deliverables including signal, benefit-risk evaluation and risk management activities for specific products. This individual must effectively interface cross-functionally at all levels in the organization as well as with external Regulatory Authorities. This individual will work together with PV management to ensure the safety assessment of priority product/s, including review of aggregate safety analyses and scientific literature, preparing safety reports and communicating changes in the product risk profile to internal and external stakeholders. The ability to work in a dynamic, changing environment to meet corporate and patient needs is essential. Essential Functions Job Responsibilities and Requirements: Lead the preparation and review of safety-related section(s) for product/s. Documents include review of specific clinical, regulatory, and scientific documents including protocols, informed consent/assent forms, case report forms (CRFs), statistical plans, clinical study reports/synopses, integrated summaries of safety, New Drug or Biologic License Applications (NDA/BLA), Marketing Authorization Applications (MAA), Common Technical Document (CTD) submissions, Regulatory Agency responses, IRB/EC requests, briefing books, manuscripts/journal articles and other documents as needed, ensuring safety profile reflected for assigned product/s. Be a key member, as the safety representative, to a Global Regulatory Team and to a Core Development Team. Interface with Risk Evaluation and Mitigation Strategy (REMS) team to optimize risk management of assigned products from a PV perspective. Where relevant, support creation and maintenance of Company Core Safety Information (CCSI) and ensure implementation of CCSI in all Reference Safety Information (RSI) including Investigator Brochures (IBs), Company Core Data Sheet (CCDS), national labels and other associated product labeling. Support review of medical/scientific literature to identify literature relevant for signal detection activities and aggregate reporting for assigned product/s, as needed. Support signal detection activities to ensure signal identification, evaluation, validation, for assigned product including individual and aggregate data analyses; interpretation of safety signals and trends; documentation and communication of safety assessments (written and verbal) of safety risks in collaboration with CRSO and PV management. Participate in or Lead a Safety Management Team (SMT) for an assigned product. Contribute to the preparation and review of pre- and post- marketing aggregate safety reports IND Annual Reports, and 6-monthly Suspected Unexpected Serious Adverse Reactions (SUSARs) Line Listing Reports and ensure consistent communication of safety profile/topics across various regulatory safety documents for assigned product/s. Contribute to preparation of Risk Management Plans (RMPs) for assigned products ensuring identification of risks, appropriate risk minimization and effectiveness measures in accord with regulatory requirements. Provide guidance with adverse event (MedDRA) and drug (WHO Drug) coding for clinical and postmarketing safety data. Demonstrate or gain knowledge of current and applicable global PV regulations and guidelines (e.g., CIOMS, EMA, FDA, ICH, etc.), SOPs and quality standards. Provide safety expertise to due diligence activities, if/ as needed. Keeps abreast of new PV/safety regulations and guidance from the regulatory authorities. Required Knowledge, Skills, and Abilities Minimum Requirements Minimum 2-5 years of Clinical Development, Medical Affairs or Drug Safety/Pharmacovigilance experience; other relevant medical affairs experience may be considered. Excellent knowledge of drug development process. Requires a high level of initiative and independence. Must have excellent written and oral communication skills, resourcefulness and personal organization skills together with demonstrated cross-functional teamwork. Computer literacy with proficiency in external Regulatory Databases, Microsoft Excel, PowerPoint and Word. Some national/international travel may be required. Leadership Skills Enterprise and Proactive Mindset—demonstrate collaborative spirit, understanding the benefit of working with others cross functionally, in a dynamic environment. Set & Achieve Goals: Understand business objectives and effectively translate them into strategies, while skillfully navigating obstacles and resistance to change. Inspire & Mobilize Others: Serve as a positive role model – create followership and effectively mobilize and influence others, both on your teams and across the organization. Understanding of target product profile; clinical designs and/or global PV regulatory environment with working knowledge of international regulations, initiatives, standards and Good Clinical and Pharmacovigilance practices (GCP, GVP). Exposure to working relationship with the FDA, EMA and other regulatory authorities is preferred. Working knowledge of safety databases (ARISg, ARGUS, or other safety database applications) and electronic data capture systems a plus. MedDRA trained and working knowledge of MedDRA and WHO Drug coding dictionaries a plus. Ability to manage multiple tasks with deadlines in fast-pace environment. Required/Preferred Education and Licenses MD required; medical licensure in at least one region preferred; clinical research and/or fellowship training in internal medicine, oncology, neurology, or other relevant specialty is a plus. #LI-Remote Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. FOR US BASED CANDIDATES ONLY Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $(phone number removed) - $(phone number removed) Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis. At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here

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