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Senior Scientist I - Characterisation | CMC - Oxford Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industrys most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.To characterise the companies biotherapeutic recombinant T-cell receptor based and related molecules using a wide variety of protein characterisation and mass spectrometry methods. To contribute to the development of characterisation methods for the companys biopharmaceutical products, including peptide mapping (LC-MS/MS) and intact mass spectrometry analysis. KEY RESPONSIBILITIES* Supporting drug substance and drug product impurity characterisation and identification* Performing protein sequence and post translational modification identification, including glycosylation analysis. * Supporting drug substance and drug product process development by performing characterisation of process intermediates * Contribute to the Development of characterisation methods of ImmTAX and other products, including peptide mapping (LC-MS/MS) and intact mass analysis * Designing and carrying out biochemical characterisation, chemical stability and comparability studies of biologics/drug products. * Contribute to writing study protocols and reports.* Independently testing and, increasingly, leading lines of investigation. Proposing new experiments based on emerging data and other related information. Providing support on technical aspects to others. * Priorities: establishing priorities for own work and team-based projects; making decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance. * Technical Knowledge: sharing knowledge with the wider team and, across departments representing the department. May also act as a mentor to other colleagues, sharing scientific knowledge. Providing analysis of new techniques and theories from outside the Company to advance the way the company works; sharing these with leaders across the department. * Laboratory records: ensuring that all records and information are up to date, on time and recorded to the correct standard. Supporting and encouraging others to achieve this.* Laboratory equipment: providing technical guidance to others within the team on how to use equipment most effectively.* Reporting: communicating and presenting research findings at meetings with colleagues, senior management and partners.* Adhere to safe working practices in laboratories according to Immunocore EHS policies.PERSON SPECIFICATIONExperience & knowledgeEssential* Experience in development of HPLC based peptide mapping methods and mass spectrometric characterisation of recombinant proteins or antibodies. * Experience of glycosylation analysis of recombinant proteins or antibodies.* Independently coordinated extensive testing of protein biomolecules.* Experienced in the characterisation of proteins expressed in both microbial and mammalian systems.* Understanding of expected post-translational modifications in biological systems.* Worked in a bench-based biopharmaceutical laboratory environment. * Established as an expert amongst peers in one or more of the following areas: o electrophoretic o chromatographic o mass spectrometry* Experienced in assay development * Familiar with biopharmaceutical stability study principles and interpretation thereof* Worked and contributed actively in a diverse team environment* Proposed and driven changes in working practices that have improved efficiency, supported teams through adoption and change* Presented detailed scientific findings and papers to internal and external audiencesDesirable * Experience of glycosylation analysis of recombinant proteins or antibodies* Experience with late stage/commercial biopharmaceutical assay development and characterisation * Familiar with the principles of Good Manufacturing Practise (GMP)* Presented at external conferences* Led a small project team, formally or informally, through a change in practice including project management * Understanding of analytical requirements to support materials for use in clinical trialsEducation & qualifications* Essential: BSc. Or MSc. in biochemistry, biotechnology or related discipline* Desirable: PhD in related discipline

Scientist - Infectious Diseases - Oxford Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industrys most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.The primary purpose of this role is to contribute to cross functional efforts focused on applying the ImmTAX® platform or other modalities to the development of novel treatments for chronic infections, including HIV and HBV and EBV-associated diseases. The team is involved in multiple stages of the drug discovery and development process, from target discovery all the way to clinical trials. Examples of key preclinical research are published in Yang H et al., Mol Ther. 2016; 24,11; Fergusson J et al., Hepatology 2020; 72,5; Wallace Z et al., Mol Ther 2024; 32, 678.The postholder will plan, design and execute experimental investigations to support the advancement of the Company pipeline, processes and technology capabilities, with guidance from their manager, ensuring that project goals are met within time and budget constraints. They will be expected to demonstrate technical proficiency, rigour in assessing their own data and that of others, scientific creativity and independent thought. This position requires participation and presentation of results at internal meetings, sharing information learned at external scientific meetings and establishing productive relationships with colleagues across Research and other departments.Key Responsibilities: * With instruction and guidance from manager - plan, design, and execute assignments to meet project goals within defined timeframes* Execute experiments to address key scientific questions and enable project progression, utilizing range of molecular and cellular techniques including some of the following: NextGen sequencing, DD-PCR, qPCR, cell culture, flow cytometry, ELISpots, ELISAs,* Some work will be conducted in a containment level 3 (CL3 facility) and will require handling of human viruses* Analyse data, interpret results, and make recommendations* Proactively expand scientific/technical knowledge in relevant fields including HIV/HBV/EBV related disease biology and drug development through review of scientific literature/ conference updates, peer to peer mentoring, and attendance at seminars/conferences in line with company strategy* Work effectively in a matrixed team structure and as part of cross functional teams * Participate and present results at internal meetings* Establish relationships and possible collaborations within and outside of the companyEducation, Experience and Knowledge: Essential Qualifications: * PhD in molecular biology, cell biology, genomics, virology, immunology, or related discipline and 0-2 years related experience* Alternatively, a BSc or MSc with significant work experience in relevant scientific areas * Worked in a bench-based laboratory environment and proficient inthe following key techniques:o molecular techniques including some of the following: Droplet Digital PCR, NextGen sequencing, Genomics/Transcriptomics, PCR, Mutagenesis, qPCRo Culturing primary cells and/or cell linesPreferred Qualifications: * Knowledge/expertise of Immunology/HIV/HBV/EBV* Flow cytometry, ELISAs, ELISpots * Viral integration site analysis

A flexible opportunity that works around you whether you're looking for Full or Part-Time. Imagine working for yourself, close to home, at your pace, around your lifestyle and commitments. Our network of over 1200 local Advisors enjoy these benefits, alongside great earnings. Hillarys, established over 50 years ago, remains the UK's leading provider of window furnishings solutions with an annual turnover of £250m. We're still enjoying strong growth and looking for more Advisors to join our team. Our Advisors visit customers at home to advise on and measure for a wide range of products solutions. Once manufactured and delivered, they return to install for a beautiful finish every time. If this is unlike anything you've done before that's ok – most of our self-employed Advisors started from the same position and have gone on to run successful Hillarys businesses for many years with our support – we are the experts after all. If you have a great personality, are approachable, a good communicator and care about great Service, you're already halfway there. We make it easy to find out more so why not join us on a virtual Discovery Session and learn everything you need to know about being a Hillarys Advisor. You can ask a current Advisor and one of our Area Managers any relevant questions – all from the comfort of your armchair with zero commitment! Work for yourself, not by yourself : the benefits of your own local business, within a model that removes the worries: We're experts in advertising so you won't worry about finding customers Have the confidence that over 70% of customers go on to purchase from their Hillarys Advisor You can focus on outstanding Service, ensuring your customers buy, and come back time and again Flexible hours to suit your lifestyle: manage your own diary and the time you want to commit There's a reason that so many Hillarys Advisors are successful. We're just as committed as you to the partnership – that starts with a comprehensive package: Training-for-life, local business support, a plan that's built around you, and all the things you'll need to ensure a professional approach and finish from day one: All the professional and practical Training you'll ever need as you start and develop your business. Comprehensive Sales Toolkit including complete Product samples, Tablet and software Full Installation Toolkit, including all measuring equipment, and tools (including power tools) A professional image – Hillarys branded clothing, and personalised business cards & leaflets This is wrapped into a one-off investment of just £2995 and we've even got flexible ways to pay to help spread the investment. This is unquestionably the most simple and effective way to access the UK's best opportunity. On top of the points above, you'll need to hold a valid UK driving licence to get to customers locally. To find out more complete the application form online, join one of our 45-minute Discovery sessions and learn about how good a fit Hillarys could be for you? TPBN1_UKTJ

A cutting-edge biotech firm in Oxford seeks a Senior Computational Genomics Scientist/Bioinformatician to turn complex genomic data into biological insights.This role entails designing and implementing analysis pipelines, owning analyses from questions to interpretation, and developing bioinformatic

On our Graduate Development Programme, you take the driver's seat in your career. Also check out our Connectr platform for tips and advice on applying - you can even message your questions directly to one of our graduate mentors. Please contact us confidentially at graduates@atkinsrealis.

Accommodation Advisor Salary: £28,995.75 pa + Benefits Location: HMP Bullingdon with support across the wider region. Rebuilding your life after prison is one of the toughest challenges a person can face. But with the right support, it's possible. That's where you come in. We're looking for an Accommodation Advisor to join the team- someone with a rare mix of compassion, resilience, organisation and flexibility. This is for the person who understands that rehabilitation isn't just about offering advice; it's about rolling up your sleeves and proactively supporting individuals on their journey towards securing stable accommodation and rebuilding their lives. About the Role: You will be based from the prison with some cover across probation offices and will work with a caseload of individuals to provide advice and support relevant to their housing needs. You'll carry out initial assessments to understand needs and agree an action plan. This may include support to end/sustain a tenancy, find accommodation or basic budgeting advice. Whilst we don't provide accommodation, we work with organisations that do, and nurturing these relationships is key in this role. You'll travel between sites, meeting people where they are, so no day will be the same and the ability to travel is essential. What You'll Be Doing: Collaborating with key partners: You'll work alongside probation and other stakeholders to secure housing solutions i.e local authorities, housing strategy teams and landlords. Caseload management: You'll manage multiple individuals, balancing their needs while keeping up with all the related admin. Working to KPI's: You'll be responsible for meeting performance targets and deadlines. Success in this role requires strong time management, prioritisation, and a results-driven approach to ensure the best outcomes. Quality Recording: Keep thorough records of all your work on our IT system, ensuring progress is properly tracked. What We're Looking For: Relationship Building: You're able to connect with people at all levels, engaging with key stakeholders within prisons and probation. You will build relationships with service users in a way that's genuine, promotes a sense of trust and is non-judgmental. IT and Administrative skills: Keeping meticulous records of every interaction within strict set timelines to measure client progress and ensure effective interventions. Safeguarding awareness: You are supporting complex individuals at a challenging time in their lives and will need to be able to identify any safeguarding risks. Ownership: You will be the sort of person who thrives on taking ownership, even during the busiest of times and is motivated by getting results. This role will require flexibility to travel when needed. We particularly welcome applications from those with experience in housing and an awareness of housing legislation What We Offer: At Ingeus, we listen to our employees and have developed a benefits package that supports both your personal and professional well-being: 25 days of annual leave plus bank holidays, with the option to trade for additional leave. EAP Support programme available 24/7, including 6 free counselling sessions. Private medical insurance and life assurance . Up to 2 days of Community Giving (volunteering) each year to support a cause that matters to you. Eyecare vouchers to help with glasses or eye care. Exclusive discounts via Perks at Work . Cycle to Work scheme and travel season ticket loan . Long service awards to celebrate your commitment. Salary Finance offering financial education and advice. The opportunity to purchase extra benefits like critical illness cover and dental insurance . Whilst we welcome applications from those with lived experience, this role requires an enhanced DBS check and HMPPS EL1 vetting. As we wait for the necessary background checks to be completed, you'll have plenty of opportunities to shadow your colleagues, ask questions, and learn the ropes. Our Justice division is dedicated to transforming lives and creating safer communities. Our mission is to reduce reoffending, build stronger communities, and help people realise their potential. At Ingeus, we've spent time listening to our employees to build our benefits package; 25 days of annual leave plus bank holidays, with the option to trade for additional leave. EAP Support programme available 24/7, including 6 free counselling sessions. Private medical insurance and life assurance . Up to 2 days of Community Giving (volunteering) each year to support a cause that matters to you. Eyecare vouchers to help with glasses or eye care. Online Shopping discounts Cycle to Work scheme and travel season ticket loan . Long service awards to celebrate your commitment. Salary Finance offering financial education and advice. The opportunity to purchase extra benefits like critical illness cover and dental insurance . We understand that everyone's journey is different, and we're committed to making our recruitment process as inclusive and accessible as possible. If you require any support or adjustments-whether that's help with the application, interview format, or anything else-we're here to listen and work with you to find the best approach. Our goal is to ensure you can showcase your skills and potential in a way that works for you. Please don't hesitate to contact us at to discuss how we can support you If you think you have what it takes, don't delay and apply today - If we receive enough applications, this role may close early. TPBN1_UKTJ

Should you have any questions or wish to apply please do not hesitate to contact Clear IT Recruitment Limited. This is an excellent opportunity to work within a supportive, people-focused practice that forms part of a wider top-40 accountancy group, offering strong progression, high-quality clients,

Machine Learning & Global Health network on machine learning for public policy and global health (EPSRC funded). Postdoc at Oxford: machine learning & global health. Any questions, please get in touch or reach out to anyone from the Machine Learning & Global Health Network: .

Our clients come to us with challenges and questions ranging from deciding on new product development, designing a new price strategy, and much more! NielsenIQ’s Analysts work with our clients to create and present analyses based on the world’s best datasets. Our Analysts are vital to NielsenIQ�

Should you have any questions or wish to apply, please do not hesitate to contact Clear IT Recruitment Limited. This is an excellent opportunity to work within a supportive, people‑focused practice that forms part of a wider top‑40 accountancy group, offering strong progression, high‑quality c