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A clinical-stage biotechnology company headquartered in the Bay Area is seeking a highly skilled, proactive High-Throughput Synthetic Chemist to join its Discovery Synthesis team. This role will support a small-molecule research pipeline through the design and rapid delivery of high-quality compounds (milligram to multi-gram scale). We are particularly interested in chemists who have applied modern synthetic technologies to solve complex problems, including areas such as photocatalysis, electrochemistry, or transition metal catalysis, ideally within high-throughput or parallel experimentation environments. This modern catalysis would be in the specific areas of radical cross couplings (transition metal, photochemical, or electrochemical catalysis). Additional key experience would be with "sp2/sp3" or "sp3/sp3" cross couplings. Location: South San Francisco, CA (Onsite) Key Responsibilities • Design and synthesize small-molecule analogs., • Develop and execute efficient synthetic routes, including multi-step syntheses and late-stage diversification strategies., • Utilize parallel or high-throughput approaches to generate focused compound libraries., • Troubleshoot and optimize challenging reactions with scientific rigor and independence., • Scale synthesis of intermediates and final compounds from milligram to decagram quantities., • Collaborate closely with Medicinal Chemistry and cross-functional project teams to advance program goals., • Coordinate with external CRO partners to plan and troubleshoot synthetic activities., • Purify and characterize compounds using NMR, LC-MS, and related analytical techniques., • Maintain high-quality electronic lab documentation suitable for IP and regulatory standards., • Clearly communicate experimental rationale, progress, and results to internal and external stakeholders.Qualifications, • M.S. or Ph.D. in Organic Chemistry or related discipline with 4+ years of pharmaceutical or biotechnology industry experience., • This modern catalysis would be in the specific areas of radical cross couplings (transition metal, photochemical, or electrochemical catalysis)., • Key experience with "sp2/sp3" or "sp3/sp3" cross couplings., • Strong foundation in modern synthetic organic chemistry with demonstrated application of enabling technologies (e.g., photocatalysis, electrochemistry, transition metal–mediated transformations)., • Experience with parallel synthesis, high-throughput experimentation, or automated reaction platforms., • Proven ability to design and execute robust, scalable multi-step syntheses., • Experience delivering high-quality compounds across varying scales., • Prior experience working effectively with CRO partners., • Excellent documentation practices and strong analytical interpretation skills., • Strong communication skills and collaborative mindset.#IND-SPG Estimated Min Rate: $65.00 Estimated Max Rate: $77.00 What’s In It for You? We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh’s network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh’s extensive talent community that will provide you with access to Yoh’s vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include: • Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week), • Health Savings Account (HSA) (for employees working 20+ hours per week), • Life & Disability Insurance (for employees working 20+ hours per week), • MetLife Voluntary Benefits, • Employee Assistance Program (EAP), • 401K Retirement Savings Plan, • Direct Deposit & weekly epayroll, • Referral Bonus Programs Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. Visit to contact us if you are an individual with a disability and require accommodation in the application process. For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. By applying and submitting your resume, you authorize Yoh to review and reformat your resume to meet Yoh’s hiring clients’ preferences. To learn more about Yoh’s privacy practices, please see our Candidate Privacy Notice:

A clinical-stage biotechnology company headquartered in the Bay Area is seeking a highly skilled, proactive High-Throughput Synthetic Chemist to join its Discovery Synthesis team. This role will support a small-molecule research pipeline through the design and rapid delivery of high-quality compounds (milligram to multi-gram scale). We are particularly interested in chemists who have applied modern synthetic technologies to solve complex problems, including areas such as photocatalysis, electrochemistry, or transition metal catalysis, ideally within high-throughput or parallel experimentation environments. This modern catalysis would be in the specific areas of radical cross couplings (transition metal, photochemical, or electrochemical catalysis). Additional key experience would be with sp2/sp3 or sp3/sp3 cross couplings. Location: South San Francisco, CA (Onsite) Key Responsibilities • Design and synthesize small-molecule analogs., • Develop and execute efficient synthetic routes, including multi-step syntheses and late-stage diversification strategies., • Utilize parallel or high-throughput approaches to generate focused compound libraries., • Troubleshoot and optimize challenging reactions with scientific rigor and independence., • Scale synthesis of intermediates and final compounds from milligram to decagram quantities., • Collaborate closely with Medicinal Chemistry and cross-functional project teams to advance program goals., • Coordinate with external CRO partners to plan and troubleshoot synthetic activities., • Purify and characterize compounds using NMR, LC-MS, and related analytical techniques., • Maintain high-quality electronic lab documentation suitable for IP and regulatory standards., • Clearly communicate experimental rationale, progress, and results to internal and external stakeholders.Qualifications, • M.S. or Ph.D. in Organic Chemistry or related discipline with 4+ years of pharmaceutical or biotechnology industry experience., • This modern catalysis would be in the specific areas of radical cross couplings (transition metal, photochemical, or electrochemical catalysis)., • Key experience with sp2/sp3 or sp3/sp3 cross couplings., • Strong foundation in modern synthetic organic chemistry with demonstrated application of enabling technologies (e.g., photocatalysis, electrochemistry, transition metal–mediated transformations)., • Experience with parallel synthesis, high-throughput experimentation, or automated reaction platforms., • Proven ability to design and execute robust, scalable multi-step syntheses., • Experience delivering high-quality compounds across varying scales., • Prior experience working effectively with CRO partners., • Excellent documentation practices and strong analytical interpretation skills., • Strong communication skills and collaborative mindset.#IND-SPG Estimated Min Rate: $65.00 Estimated Max Rate: $77.00 What’s In It for You? We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh’s network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh’s extensive talent community that will provide you with access to Yoh’s vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include: • Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week), • Health Savings Account (HSA) (for employees working 20+ hours per week), • Life & Disability Insurance (for employees working 20+ hours per week), • MetLife Voluntary Benefits, • Employee Assistance Program (EAP), • 401K Retirement Savings Plan, • Direct Deposit & weekly epayroll, • Referral Bonus Programs Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. Visit to contact us if you are an individual with a disability and require accommodation in the application process. For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. By applying and submitting your resume, you authorize Yoh to review and reformat your resume to meet Yoh’s hiring clients’ preferences. To learn more about Yoh’s privacy practices, please see our Candidate Privacy Notice:

Job DescriptionSalary: $90K-$95K, DOE Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to support the life sciences industry with specialized laboratory services delivered by professional scientistsadvancing research, fostering collaboration, and accelerating innovation with quality and a commitment to excellence. We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation. Cogent Scientific offers competitive pay (with relocation bonus as needed), attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment.We aim to recruit the best people who stand out among their peers and embody our Core Values: Client Focused: We only succeed when our clients succeed. Outstanding: We deliver meticulous results through outstanding performance. Good: We act ethically and morally. Employee-Centric: We honor and support our employees. Nimble: We are prepared to adapt in an ever-changing industry. Team-Oriented: We collaborate with each other and with our clients. We currently have a role available for a Bioanalytical Chemistat our South San Francisco site. Job duties include, but are not limited to: • Support Bio-Analysis sample preparation, design and perform mass-spec analysis as well as data analysis/interpretation from in-vivo studies from triple-quad mass spectrometers (Sciex 7500)., • Experience operating, maintaining Sciex 7500 Qtrap, triple-quad mass spectrometers, or Orbitrap instruments is required., • Must be able to work independently to design and execute experiments, and has a track record of conceiving creative solutions in the lab to answer complex questions., • Must be proficient in troubleshooting mass spec and LC systems from common vendors., • Experience with cell culture, PK, and Bio-Analysis of ADC drugs from complex matrices (plasma, tissue)., • Characterization of recombinant proteins, antibodies, and ADCs using intact-MS and peptide mapping for routine QC using high-res mass spec platforms (Oribtrap)., • Must have a minimum of 2-5 years of hands-on laboratory experience working with mass spectrometry focused approaches in a discovery setting to support drug development., • Extensive hands-on experience operating and maintaining LCMS instrumentation as well as SEC/HIC or U/HPLC systems, and proficient in the software used for data analysis (Protein Metrics, Skyline, Biopharma Finder) is required., • Experience in analytical characterization using SEC/HIC, U/HPLC, cIEF, CE, as well as experience running nano-LCMS instruments for proteomics is desirable., • Work closely with a team of scientists to support the development, optimization, and execution of analytical assays for protein characterization and bioanalysis to guide large molecule therapeutic design., • Experience with high throughput plate-based assays working on both large and small molecules is beneficial., • Collaborate with the team to meet timelines and deliverables., • The successful candidates demonstrates a "can-do" attitude and brings innovative ideas to challenging projects to contribute to a collaborative and cross-functional organization, • Perform general lab maintenance and instrument calibrations., • Must be experienced with molecular biology, analytical techniques, and general lab practices, and presenting and interpreting complex datasets in Excel and Prism., • Maintain a high level of productivity in a laboratory setting, this role is 100% on site in South San Francisco and is lab based, but will have opportunities to represent data with project teams., • Experience with analyzing and reporting analytical data, presenting data to colleagues and collaborators, and being a subject area expert in mass spec and analytical approaches is highly advantageous., • Experience with R for data visualization is advantageous. Job requirements include, but are not limited to: • Minimum of a BSc with 2-5 years industry experience or MSc with 1-2 years industry experience in a mass spec focused lab on antibodies/ADCs/ proteomics or in a relevant scientific discipline focused on mass spec and ADCs., • Team player mentality with strong written and verbal communication skills. Must have good organizational skills and must be detail oriented., • The ideal candidate will be enthusiastic and self-motivated, with the strong interpersonal, communication, and organizational skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery. Cogent Scientific provides equal employment opportunities to all applicants and does not discriminate based on any legally protected characteristic. Additionally, if you require a reasonable accommodation during the application or interview process, please let us know. This job posting will close by 4/30/2026 or when a candidate is identified, whichever comes first.