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Director, Cardiovascular and metabolic diseases, Clinical Pharmacology Modeling and SimulationFor candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. Do you have the right skills and experience for this role Read on to find out, and make your application. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.The Department of Clinical Pharmacology Modelling & Simulation in Respiratory and Inflammation (CPMS R&I) at GSK is recruiting for a Director–level Clinical Pharmacologist with cardiovascular and metabolic disease expertise.This role sits within the newly established Clinical Pharmacology and Quantitative Medicine (CPQM) organisation, which aims to be a centre of excellence in Model‑Informed Drug Development (MIDD) by integrating clinical pharmacology, digital medicine, translational imaging and mechanistic/systems modelling.You will lead the end‑to‑end application of MIDD across the drug development lifecycle • from first‑in‑human studies through filing and lifecycle management, • and provide clinical pharmacology strategy and evidence‑generation input. This is an opportunity to join a highly regarded, high‑impact team with a strong publication track record, reporting directly to the Respiratory, Immunology & Inflammation Research Unit (RIIRU).Main responsibilities and accountabilities include, but are not limited to:• Design & Execute Model Informed and Clinical Pharmacology strategiesDevelop and implement robust MIDD & ClinPharm evidence strategies to de risk and accelerate RIIRU programs. Aim for faster development, optimal dosing and stronger regulatory positioning across respiratory, inflammation, neurodegeneration and emerging areas — and support business development opportunities.• Ensure robust ways of working and regulatory ready evidenceDraft and review clinical pharmacology regulatory content to support timely approvals and optimal labelling. Maintain up to date knowledge of FDA, EMA, CDE, PMDA and ICH expectations and embed regulatory considerations and best practices into study design and MIDD strategies.• Build cross functional partnershipsWork closely with CPQM peers (digital medicine, translational imaging, MIDD specialists, mechanistic/systems modelling) and cross functional partners (biology, data science, computational biology, clinical, etc.). Maintain strong networks and share best practices in the CPMS community of practice. Build strong network key functions such as AI/ML, biomarkers, biostatistics, clinical operations, data science, computational biology and RWE to embed quantitative approaches into decision making at asset level.• External engagement & scientific leadershipRaise GSK’s profile in MIDD, clinical pharmacology, QSP and AI/ML integration through publications, conference presentations and active participation in scientific and regulatory fora to influence method adoption and regulatory dialogueWhy you?Basic Qualifications:We are looking for a professional with these required skills to achieve our goals:• PhD, MD, or PharmD• 5+ years of industry experience in clinical pharmacology, modelling/simulation and drug development to solve practical problems in pharmaceutical industry.• Experience in pharmacometrics and its application to clinical questions in drug development.Preferred Qualifications:• Experience in Cardiovascular and metabolic diseases.• Demonstrated experience of collaboration in a multi-disciplinary team, using effective communication and taking personal accountability for timely delivery of results.• Evidenced experience making sound judgement in complex situations and adapting to changing business needs by prioritizing multiple tasks.• Experience working with senior stakeholders in a cross functional environment.• Track record of implementation of Model-Informed Drug Discovery and Development (MIDD) approaches to accelerate patient access to novel therapies and to expand therapeutic indications of marketed drugs.• Drive and learning agility to build knowledge on a drug-disease system, symptom progression, standard of care, and trial design.SkillsDrug Design, Drug Development, Drug Discovery Process, Drug Discovery Research, Medication Safety, Molecular Modeling, Pharmaceutical Regulatory Compliance, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacology, Pharmacometrics, Pharmacovigilance, Study Design, Target Validation• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $188,100 to $313,500. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: USA • Massachusetts, • Waltham; GSK HQ; UK, • Hertfordshire, • Stevenage; Baar Onyx; USA, • North Carolina, • Durham; USA, • Pennsylvania, • Upper ProvidenceType: Full time

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. Be one of the first applicants, read the complete overview of the role below, then send your application for consideration. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.The Senior Medical Director, Oncology Clinical Development – Sarcoma, is a senior physician leader within the clinical programme team, providing medical oversight, strategic clinical insight, and a patient-centred perspective across the design, conduct, and interpretation of clinical studies. This role ensures that medical considerations, patient safety, and clinical integrity are consistently applied across studies within a programme.Operating within the clinical strategy defined by the Clinical Development Lead (CDL), the Senior Medical Director partners closely with the Senior Scientist and cross-functional teams to guide the integration of physician expertise into study execution and programme-level decision-making. The role serves as a senior member of the Clinical Matrix Team (CMT), contributing to complex clinical decisions, regulatory interactions, and external scientific engagement.The Senior Medical Director provides matrixed oversight to the clinical team within the programme, supporting consistency of clinical judgement, safety evaluation, and medical interpretation across studies.PLEASE NOTE: This career opportunity requires an on-site office presence (minimum of two days a week) at one of GSK’s Switzerland (Zug), UK (Stevenage or London HQ) or US (PA or MA) sites.In This Role You Will:Serve as a senior physician leader within the clinical programme, providing medical oversight and clinical insight across study design, conduct, and data interpretationProvide guidance on medical monitoring and safety oversight across studies, ensuring consistent application of clinical judgement and patient safety standardsInterpret complex clinical and safety data, generating insights that inform programme-level decisions led by the CDLPartner with the Senior Scientist and cross-functional teams to ensure medical considerations are integrated across study execution and programme deliveryProvide senior medical input into protocol development and study design, ensuring clinical relevance and patient-centred design within the clinical strategy defined by the CDLServe as a senior member of the CMT, influencing study-level and programme-level decision-makingEngage with investigators, Key External Experts (KEEs), and scientific leaders to support external engagement and represent the programme at advisory boards, steering committees, and scientific forumsProvide medical guidance and mentorship to Medical Directors within the programme, supporting consistency and development of clinical capabilityDetailed Responsibilities:Medical Monitoring and Safety Oversightconsistency in approach, patient safety, and protocol adherenceGuide interpretation of safety data in collaboration with pharmacovigilance, supporting signal detection, escalation, and benefit–risk evaluation across the programmeParticipate in and contribute to safety review forums (e.g., SRT, IDMC), providing senior physician perspective on complex safety questionsEnsure medical monitoring approaches are aligned across studies and consistent with regulatory and organisational standardsStudy Design and ExecutionProvide senior medical input into protocol development across studies, ensuring clinical relevance, feasibility, and alignment with the clinical strategy defined by the CDLGuide clinical aspects of study design and protocol implementation, particularly for complex, high-risk, or multi-study programmesSupport resolution of complex medical questions arising during study conduct, applying clinical judgement to inform programme-level decision-makingEnsure consistency of medical considerations across multiple studies within the programmeData Interpretation and Scientific ContributionInterpret complex clinical data across studies, integrating findings to inform programme-level insights on safety, efficacy, and patient impactContribute to programme-level data interpretation and support CDL-led benefit–risk assessment and clinical positioningGuide development of scientific communications, including publications, congress materials, and clinical summariesMaintain deep understanding of disease biology, evolving treatment paradigms, and competitive landscape to inform clinical interpretation and programme strategyRegulatory and External EngagementContribute senior medical expertise to regulatory interactions and Health Authority discussions, including responses to complex clinical and safety queriesRepresent the programme at advisory boards, steering committees, and external scientific forums, providing senior physician perspective on clinical data and programme directionEngage with KEEs and scientific collaborators to support programme development, scientific exchange, and external credibilityLead or contribute to the clinical and technical diligence assessment of business development opportunitiesCross-Functional Collaboration and Clinical Matrix TeamServe as a senior member of the Clinical Matrix Team (CMT), influencing cross-functional alignment and programme-level decision-makingContribute medical expertise to disease area strategy, integrated evidence planning, and Medical Affairs discussionsCollaborate across functions to ensure alignment on safety, data interpretation, and clinical positioning across the programmeLead or contribute to Oncology Clinical Development-wide initiatives and workstreamsPeople Leadership & Capability DevelopmentProvide oversight, guidance, and mentorship to clinical scientists within the programme, supporting consistency and quality of medical input across studiesSupport development of clinical capability within the medical team, including coaching on medical monitoring, data interpretation, and external engagementContribute to talent development, performance discussions, and capability building within Oncology Clinical DevelopmentBasic Qualifications:Medical degree and completion of advanced specialty training, fellowship or country-equivalent higher-level qualification in medical oncology, pediatric oncology or hematology.Experience in sarcoma oncology, including leading drug development.Clinical and pharmaceutical experience in oncology clinical development, with depth across multiple studies or programmesExperience in medical monitoring, safety evaluation, and clinical data interpretation across clinical studiesUnderstanding of clinical development processes, GCP, ICH guidelines, and global regulatory frameworksExperience operating within cross-functional matrix teams and contributing to complex clinical and programme-level decisionsPreferred Qualifications:Deep expertise in soft tissue sarcoma and osteosarcoma, including experience leading or supporting clinical development programs across early and/or late-stage clinical studies.Strong scientific communication and stakeholder engagement skills, with the ability to influence internal and external audiencesDeep experience in oncology clinical development across multiple studies or programmes, including Phase I–IIIExperience contributing to or leading aspects of regulatory interactions (e.g., IND, scientific advice, NDA/MAA)Demonstrated experience engaging with KEEs, advisory boards, and scientific communities in oncologyTrack record of scientific publications and congress presentationsDeep understanding of oncology disease biology and the evolving treatment landscape across solid tumours and/or haematological malignanciesExperience contributing to clinical and technical diligence for business development opportunities#ESMO2026SkillsClinical Data Interpretation, Clinical Pharmacology, Clinical Trial Designs, Clinical Trials Monitoring, Digital Fluency, Drug Development, Drug Regulatory Affairs, Evidence Based Decision Making, Executive Presence, Hematology and Oncology, Learning Agility, Matrix Leadership, Real World Evidence (RWE), Scientific Presentations, Strategic Direction• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $284,250 to $473,750. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receiveImportant notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: UK – London – New Oxford Street; USA • Massachusetts, • Waltham; UK, • Hertfordshire, • Stevenage; Switzerland, • Zug; USA, • Pennsylvania, • Upper ProvidenceType: Full time

DescriptionFor candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. Applying for this role is straight forward Scroll down and click on Apply to be considered for this position. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.Find out more:Our approach to R&DOverviewCancer is unrelenting, but so are we. At GSK, we are committed to transforming outcomes for people with cancer through innovative science, bold ambition, and strong partnerships across the healthcare ecosystem. We focus our science where it can matter most — advancing care in cancers with high unmet need, grounded in a deep understanding of disease biology and deliberate scientific choices that connect discovery to meaningful impact in the real world.The Medical Director, Oncology Clinical Development • GI is the physician within the clinical programme team, bringing medical expertise, clinical judgement, and a patient-centred perspective to the design, conduct, and interpretation of clinical studies. This role is accountable for medical monitoring and safety oversight, ensuring that patient safety and clinical integrity are maintained throughout study execution.Operating within the clinical strategy defined by the Clinical Development Lead (CDL), the Medical Director partners closely with the Senior Scientist and cross-functional teams to ensure that the physician perspective is fully integrated into study delivery. The role serves as a core member of the Clinical Matrix Team (CMT), contributing to study-level decisions, investigator engagement, and regulatory interactions.For more complex or multi-study programmes, the Medical Director may provide medical guidance to other physicians within the programme and contribute to broader clinical discussions that inform programme-level decisions led by the CDL.In This Role You Will:• Serve as the physician within the clinical programme team, providing medical expertise across study design, conduct, safety oversight, and data interpretation• Lead medical monitoring activities for clinical studies, ensuring patient safety, clinical integrity, and compliance with the protocol and regulatory requirements• Interpret clinical and safety data from a physician perspective, generating insights that inform study-level and programme-level decisions led by the CDL• Partner with the Senior Scientist and cross-functional teams to ensure medical considerations are integrated into study execution and delivery• Contribute medical expertise to protocol development, ensuring clinical relevance, patient safety, and feasibility within the framework defined by the CDL• Serve as a core member of the Clinical Matrix Team (CMT), providing the medical voice in study-level discussions and cross-functional decision-making• Engage with investigators and Key External Experts (KEEs) to support study conduct, scientific exchange, and external representation of the programme• Contribute to regulatory documents, Health Authority interactions, and scientific communications from a physician perspectiveDetailed Responsibilities:Medical Monitoring and Safety Oversight• Lead medical monitoring activities for assigned clinical studies, including real-time clinical decision-making on patient eligibility, protocol-related medical queries, and safety oversight• Conduct and oversee medical review of clinical trial data, both directly and through oversight of delegated medical review activities• Interpret and contextualise safety data in collaboration with pharmacovigilance, ensuring appropriate signal detection, escalation, and benefit–risk assessment at the study level• Participate in safety review forums, including Safety Review Team (SRT) discussions, Independent Data Monitoring Committee (IDMC) data reviews, and internal governance as required• Ensure medical monitoring activities are conducted in compliance with GCP, ICH guidelines, and applicable regulatory frameworksStudy Design and Execution• Provide medical input into protocol development, ensuring clinical relevance, patient safety, and operational feasibility within the clinical strategy defined by the CDL• Apply clinical judgement to support protocol implementation, addressing medical questions that arise during study conduct and ensuring consistency with the study’s scientific objectives• Partner with the Senior Scientist to ensure that medical considerations are fully integrated into study execution, data generation, and operational delivery• Contribute to the development and review of key study documents, including the Informed Consent Form (ICF), protocol deviation management plan (PDMP), and study reference manual (SRM)• Provide medical input into clinical data generation activities, ensuring alignment with study objectives, patient safety considerations, and the Clinical Development Plan (CDP)Data Interpretation and Scientific Contribution• Interpret clinical data from a physician perspective, translating findings into insights on safety, efficacy, and patient impact that inform decision-making by the CDL• Contribute to study-level and programme-level data interpretation, supporting the CDL’s assessment of benefit–risk and clinical positioning• Contribute to the development of scientific communications, including study reports, clinical study summaries, publications, and congress materials• Collaborate with investigators on the evaluation and development of abstracts, posters, and manuscripts derived from clinical programme data• Maintain current knowledge of the asset’s biological mechanism, disease landscape, evolving treatment paradigms, and competitive environment to inform clinical interpretationRegulatory and External Engagement• Contribute medical expertise to regulatory documents and Health Authority interactions, including responses to clinical and safety queries• Support preparation of materials for regulatory submissions, advisory boards, and external engagements, providing the physician perspective on clinical data and safety• Engage with Key External Experts (KEEs), investigators, and scientific collaborators to support study conduct, scientific exchange, and relationship development• Represent the medical perspective at cross-departmental interactions, including Integrated Evidence Team (IET) and Medical Affairs strategy discussions, as delegated by the CDL• Contribute to the clinical and technical diligence assessment of business development opportunities as requestedCross-Functional Collaboration and Clinical Matrix Team• Serve as a core member of the Clinical Matrix Team (CMT), providing medical leadership within study execution• Contribute medical expertise to disease area strategy, integrated evidence planning, and Medical Affairs discussions as appropriate• Collaborate across functions — including Clinical Operations, Biostatistics, Regulatory, and Pharmacovigilance — to ensure alignment on study objectives, patient safety, and data quality• Contribute to Oncology Clinical Development-wide initiatives and workstreamsWorking ModelThis position requires an on-site office -based presence 2 to 3 days a week in the UK (London or Stevenage); Switzerland (Zug); or the US (Upper Providence, PA or Waltham. MA).Basic QualificationsWe are seeking professionals with the following required skills and qualifications to help us achieve our goals:• MD (or equivalent medical degree) with board certification or eligibility in oncology, haematology, or a related specialty• Clinical experience in oncology and/or relevant therapeutic areas, with direct exposure to clinical research or drug development• Demonstrated experience in clinical trial conduct, including medical monitoring, safety review, and clinical data interpretation• Strong working knowledge of clinical development processes, including GCP, ICH guidelines, and global regulatory frameworks• Ability to apply clinical judgement to support study design, patient safety, and real-time medical decision-making within a structured clinical development framework• Experience operating effectively within cross-functional matrix teams in a pharmaceutical, biotechnology, or academic clinical trial environment• Strong scientific communication skills, with the ability to translate clinical data into clear insights for internal and external audiencesPreferred QualificationsIf you have the following characteristics, it would be a plus:• Experience in pharmaceutical or biotechnology clinical development across Phase I–III GI oncology studies• Prior experience contributing to regulatory interactions (e.g., IND submissions, scientific advice, NDA/MAA filings)• Demonstrated experience engaging with Key External Experts (KEEs), investigators, and scientific collaborators in oncology• Track record of contributing to clinical publications, congress presentations, or scientific communications• Deep understanding of oncology disease biology, evolving treatment paradigms, and the competitive landscape across solid tumours and/or haematological malignancies• Experience in medical monitoring across multiple studies or programmes within a clinical development organisation• Familiarity with emerging data and analytics approaches (e.g., real-world evidence, AI-enabled insights) to support clinical interpretation and decision-making#ESMO2026What we value in youWe act with transparency, respect and integrity. We welcome different perspectives and champion inclusion. Bring curiosity, humility and a clear focus on patients. If you are motivated to drive clinical progress and to grow with a team that values collaboration and impact, we encourage you to apply.How to applyPlease submit your CV and a short cover letter that explains how your experience matches the role and what motivates you to join us. We welcome applicants from all backgrounds and look forward to hearing from you.SkillsAnalytical Thinking, Clinical Data Interpretation, Clinical Development, Clinical Pharmacology, Clinical Trial Designs, Clinical Trials Monitoring, Digital Fluency, Drug Regulatory Affairs, Evidence Based Decision Making, Executive Presence, Hematology and Oncology, Learning Agility, Matrix Leadership, Real World Evidence (RWE), Scientific Presentations• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $222,750 to $371,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receiveImportant notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: UK – London – New Oxford Street; USA • Massachusetts, • Waltham; UK, • Hertfordshire, • Stevenage; Switzerland, • Zug; USA, • Pennsylvania, • Upper ProvidenceType: Full time

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage, UK. Please make an application promptly if you are a good match for this role due to high levels of interest. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.Director, Oncology Translational Medicine, Clinical BiomarkersJob Purpose:The Director, Oncology Translational Medicine, Clinical Biomarkers is responsible for the development and effective implementation of biomarker and translational medicine strategies to support the clinical development of late-stage oncology assets.As a key member of a Clinical Matrix Team (CMT), the Clinical Biomarker Director will collaborate with the Clinical Biomarker Executive Director to establish clear decision-making criteria, define patient segmentation strategies, and integrate these into clinical development plans.You will leverage cutting-edge technologies and methodologies to discover and clinically validate biomarkers, ensuring the biomarker strategy is fully aligned with the clinical plan. This integration will optimise decision-making in drug development and enable the identification of the right patient populations for our medicines.Key responsibilities:Collaborating closely with the Clinical Biomarker Executive Director to drive the design, alignment, and execution of clinical biomarker and translational medicine strategies focused on identifying predictive biomarkers that enable clinical success.Validating and implementing biomarker strategies, including target engagement, pharmacodynamic, and proof-of-mechanism biomarkers, for clinical-phase programs to support patient stratification, dose selection, and enable clinical go/no-go decisions.Participating in tumor-specific Biomarker Matrix teams, with responsibility for executing clinical biomarker strategies for late-stage oncology programs, while working closely with internal and external stakeholders, as well as disease area strategy teams.Representing Translational Medicine at Clinical Development Matrix Teams (CMT) to establish biomarker-driven decision-making criteria and their seamless integration into clinical study designs, aligning with clinical study objectivesSupporting disease area strategies and translational objectives by defining biomarker priorities, areas of interest, and generating decision-enabling evidence packages informed by real-world datasets, internal and external data and partnerships (For e.g., research collaborations, KEE consultations).Identifying cutting-edge science and technological advances to incorporate into biomarker strategies for guiding indication selection, patient enrichment, and combination strategies.Overseeing and/or developing sample testing plans and delivering high-quality biomarker data packages to inform clinical development and regulatory strategies.Managing effective relationships with clinical and scientific operations, diagnostics, medical science, medical affairs, regulatory, portfolio management, and commercial functions.Supporting the expansion of mechanism and disease understanding to generate insights for indication expansion and scientific exchange as needed.Defining and studying mechanisms of resistance to enable reverse translation, inform next-line strategies, support patient enrichment, and influence life cycle management of assets.Contributing to the company’s scientific credibility through publications and presentations.Why You?Basic Qualifications:We are looking for professionals with the following required skills and experience:Ph.D. or equivalent with 7+ years or M.Sc. with 10+ years of drug development experience in the pharmaceutical industry, with a solid background in Oncology clinical biomarkers, expertise in late-phase oncology studies, and translational research within clinical development.Strong expertise in cancer biology, and clinical development, including the therapeutic landscape, approved and investigational agents, and diagnostic approaches in solid tumor and haematological malignancies.Experience in leading cross-functional teams and designing and executing strategic biomarker plans including development of regulated biomarker assays.Experience conducting clinical trials and working as part of clinical study teams.Experience designing and executing translational biomarker plans for clinical trials. Explores and onboards innovative technologies to advance translational research and new biomarker developmentExperience collaborating effectively with Data Sciences to analyze high-dimensional preclinical and clinical data to guide clinical decisions and inform asset strategy.Hands-on experience implementing a broad range of biomarker platforms such as flow cytometry, molecular diagnostics including NGS, FISH and PCR, IHC/IF, liquid biopsy / ctDNA approaches, and multi-omic biomarker analyses.undefinedDirect successful translation of pre-clinical research to human clinical trials, leveraging learnings from genomic, transcriptomic, and proteomic analyses of both preclinical models and patient samples.Experience influencing teams and key leaders, with a track record of success.Preferred Qualifications:The following qualifications would be advantageous:M.D., Ph.D. or equivalent doctoral degree in a relevant scientific discipline.Experience with high-dimensional dataset analysis.Prior experience with diagnostic development and regulatory interactions.Experience with digital pathology, AI/ML-enabled biomarker analyses, external scientific partnerships, and mentoring or developing scientific colleagues.Strong sense of urgency and excellent skills in prioritization, planning as well as timely execution in a very fast-paced environmentStrong interpersonal skills and ability to thrive in a matrixed environment. Dependable and trustworthy, willing to take ownership and responsibilityExcellent communication, problem-solving, matrix project-management, and presentation skills.LI-GSK *LI-Hybrid *SkillsAnalytical Thinking, Clinical Data Interpretation, Clinical Data Review, Clinical Development, Clinical Trial Designs, Clinical Trials Monitoring, Digital Fluency, Drug Regulatory Affairs, Executive Presence, Hematology and Oncology, Learning Agility, Matrix Leadership, Real World Evidence (RWE), Scientific Presentations• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $189,750 to $316,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: USA • Pennsylvania, • Upper Providence; GSK HQ; UK, • Hertfordshire, • Stevenage; WalthamType: Full time

100000 Please double check you have the right level of experience and qualifications by reading the full overview of this opportunity below. • 140000 per annum + bonus / car allowance Hertfordshire, EnglandPermanentOur client is a leading civil engineering, groundworks and infrastructure contractor delivering complex projects across the UK. Due to continued growth and an expanding project portfolio, they are seeking an experienced Commercial Director to lead the commercial function and drive performance across the business.This is a high-profile leadership appointment for an accomplished commercial professional with a proven track record within groundworks, civil engineering and infrastructure environments.The RoleReporting into the senior leadership team, the Commercial Director will take full responsibility for the commercial operation of the business, ensuring strong financial performance, effective governance and commercial excellence throughout the project lifecycle.Key responsibilities include:Leading and managing the entire commercial function.Overseeing projects from tender stage through to final account and post-completion.Managing all procurement and buying activities.Driving commercial strategy and business performance.Full P&L responsibility.Producing and managing cashflow and pipeline forecasts.Overseeing management accounts and commercial reporting.Ensuring robust commercial governance and risk management.Supporting business growth and maintaining strong client relationships.Candidate ProfileThe successful candidate will be able to demonstrate:Significant experience within groundworks, civil engineering and infrastructure contracting.A strong background in senior commercial leadership roles.Extensive experience managing the full commercial lifecycle of major projects.Strong working knowledge of NEC forms of contract.Experience within a self-delivery contractor, Tier 1 contractor, or ideally both.Exceptional commercial acumen with proven responsibility for profitability, forecasting and financial control.The leadership skills to build, mentor and develop high-performing commercial teams.Location & TravelBased from the Hertfordshire office with regular travel to project locations as required.Projects are located across Suffolk, the Midlands, Manchester and Scotland.Travel expenses will be covered where applicable.Working ArrangementThis is a hands-on leadership position requiring a regular presence within the business and across project sites.Primarily office and site-based.Five days per week working from office, project locations or other business locations as required.Flexible working may be considered in exceptional circumstances but is not offered as a standard remote-working arrangement.PackageA highly attractive and fully negotiable executive package is available for the right individual, reflecting the importance and seniority of this appointment. xrnqpay To be successful in this role, candidates must possess a demonstrable track record of commercial leadership within the groundworks, civil engineering or infrastructure sectors.

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. Submit your CV and any additional required information after you have read this description by clicking on the application button. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.Find out more:Our approach to R&DWe are seeking an experienced Medical Director Clinical Development- Respiratory to join GSK’s Respiratory, Immunology & Inflammation Research Unit. In addition to providing clinical and scientific leadership to clinical and translational studies or programs for asset-level projects, you will contribute to the assessment of potential mechanisms and targets, target validation programs, life-cycle expansion, and innovative clinical development opportunities. You will work cross-functionally to develop and execute clinical development plans (CDPs) and contribute to above-project development of foundational and real-world data, and translational and biomarker capabilities, within a department that prioritizes understanding mechanism and unmet need alongside innovative clinical development, helping us deliver differentiated medicines that change the course of disease and improve patients’ lives.In the Respiratory, Immunology, and Inflammation Research Unit (RIIRU), our enduring purpose is to leverage immune science to address underlying organ dysfunction and disease. We are trailblazing a pipeline of medicines to dramatically improve how we cure and care for patients. We are a diverse team of industry-leading experts who channel our passion for scientific exploration into true value for patients and GSK. We drive the end-to-end R&D journey, fueling early discovery and our mid-stage pipeline while also advancing our late-stage medicines to launch. We are combining field-leading data sets, capabilities, and methods with decades of knowledge, to transform our success in how we innovate new medicines.Working model:This role is hybrid. You will be on-site at one of the posted locations at least two days per week. Remote work is available on other days.Position Summary:This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:Support alignment of translational and clinical plans and study designs with project strategies to ensure quality design and execution of the CDP. Develop sections of core regulatory documents.Generate the data and evidence required to determine a target’s potential efficacy, safety profile, key areas of differentiation and route to becoming a medicine with value to patients in the shortest possible timeframe.Define and deliver the clinical pillars of the translational table.Deliver clinical development and study timelines and endpoints, including pharmacology, mechanism, and clinical efficacy endpoints, enabling key decision points and Go/No Go criteria for the CDPEstablish and maintain relationships with program counterparts in Biology, Translational Sciences, Commercial, Regulatory, Clinical Operations, Market Access, Medical Affairs and Statistics.Contribute to the implementation and embedding of strategic initiatives and various organizational initiatives in Clinical Development.Clinical Development Strategy and Study & Program Design Provide effective support and oversight of R&D evidence generation strategy, plan, and activities to ensure patient safety and on-time, in-full study delivery. Contribute to the study team discussions on indication planning and incorporate input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc.) to contribute to vital deliverables including early medicine profile, target validation, translational plans, candidate selection.Design clinical development plans, study protocols, and associated documents across all phases of development, reflecting internal and external stakeholder input (e.g., patients, evidence generation, regulators, payors, pharmacovigilance).Bring clinical expertise to regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.Provide medical monitoring and oversight of the safety of study participants on behalf of the Sponsor during the study, together with Pharmacovigilance Physician.Accountable for medical governance across the project to ensure scientific integrity and overall safety of the study subjects across the study.Clinical Leadership Accountable for leading the Clinical Matrix Team (CMT) for a program. Serves as a clinical point of contact both internally and externally for an indication of an asset or for a clinical study. Represents the CMT at Early/Medicine Development Teams or clinical study at CMT.Actively leads the end-to-end clinical development strategy for an early program and may contribute to later stages.Serve as the primary Clinical point of contact for an investigational agent (early development) or clinical study for internal and external stakeholders, including regulatory agencies, key opinion leaders, and clinical investigators and with the relevant internal review boards (e.g., Technical Review or Governance) and/or Protocol Review Board.Assist with clinical evaluation of business development opportunitiesStay abreast of advancements in research, clinical trial methodologies, competitive environment, and regulatory space in the relevant disease area to maintain GSK’s competitive edge.Identify and highlight transformational opportunities, where projects can offer highly significant benefit to patients in ways not possible with existing approaches.Gather and supports the integration of inputs from across disciplines (scientific, clinical commercial, regulatory) to contribute to clinical components of the Medicine Profile (MP).Consistently contribute to solving study and overall clinical development challenges.Demonstrate ability to influence others at project, departmental and inter-departmental levels, as appropriateCreating Innovative Scientific and Technical SolutionsEmbrace challenge as an opportunity for creativity and use new learning and digital tools to create innovative approaches to science and technical solutions.Promote an environment for others to generate ideas for improvement and proactively drives innovation, beyond taking advantage of opportunities that arise.Influencing and Inspiring Others and Managing Conflict Consistently achieves desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support.Able to consistently inspire others by setting a positive example, communicating a compelling vision, and creating an environment where team members feel valued and motivated.Manage conflicts effectively and independently, negotiating mutually acceptable solutions.Enterprise Mindset, Strategic Thinking and Navigating Ambiguity Demonstrate enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.Analyzes, interprets and critically evaluates data, information, and digital content to interpret complex information, anticipate obstacles and identify potential solutions.Demonstrate flexibility and adaptability in changing environments, able to analyze incomplete information, identify potential risks and implications, and make informed decisions.Why You? Basic Qualifications:We are looking for professionals with these required skills to achieve our goalsMedical DegreeCompletion of a formal postgraduate clinical training, clinical residency or specialty training in Internal Medicine, Pathology, etcDemonstrated experience in clinical trial conduct, including medical monitoring, safety review, and clinical data interpretationStrong working knowledge of clinical development processes, including GCP, ICH guidelines, and global regulatory frameworks Ability to apply clinical judgement to support study design, patient safety, and real-time medical decision-making within a structured clinical development framework Experience operating effectively within cross-functional matrix teams in a pharmaceutical, biotechnology, or academic clinical trial environment Strong scientific communication skills, with the ability to translate clinical data into clear insights for internal and external audiencesPreferred Qualifications: In addition to the above, you will stand out if you bring the followingCompletion of advanced specialty training, fellowship or country-equivalent higher-level qualification leading to recognition as a medical specialist through formal certification, board certification, or country specific professional designationRobust knowledge of pulmonary hypertension research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution highly preferredExperience in pharmaceutical or biotechnology clinical development across early phase studiesClinical experience in relevant specialty and/or relevant therapeutic areas, with direct exposure to clinical research or drug development in industry or postgraduate workKnowledge of and experience in the execution of clinical and/or translational studies including generation and analysis of human translational data and conduct of preclinical biological experiments in relevant model systems.Experience working with global regulatory agencies and managing global clinical trials in relevant disease areaPrior experience contributing to regulatory interactions (e.g., IND submissions, scientific advice, NDA/MAA filings)Demonstrated experience engaging with Key External Experts (KEEs), investigators, and scientific collaborators in aging disease areasDemonstrated ability to work collaboratively in cross-functional teams and a matrix environment to design and execute trials to regulatory standards.Experience in contributing to IND/CTA, NDA, BLA, or MAA submissionsSkillsClinical Development, Communication, Drug Regulatory Affairs, Evidence Based Decision Making, Good Clinical Practice (GCP), Influencing Without Authority, Learning Agility, People Management, Project Management, Scientific Presentations, Strategic Thinking• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $222,750 to $371,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receiveImportant notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. xrnqpay This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: UK • London; USA, • Massachusetts, • Waltham; UK, • Hertfordshire, • Stevenage; Stevenage; USA, • Pennsylvania, • Upper ProvidenceType: Full time

Job IntroductionDirector, Strategic Partnerships, CMCLocation: Remote (UK)About PharmaronPharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the UK, US, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services.We're proud of the impact we make and just last year, we supported 887 discovery projects, 1,100+ CMC programs, and 1,397 clinical trials across all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,300 global customers. To learn more, visit .As a Director, Strategic Partnerships, CMC, you will play a key role in driving the growth of Pharmaron’s small molecule CMC business by building and expanding strategic relationships with major pharmaceutical clients.This is a highly visible, client-facing role where you will combine deep industry knowledge with strong commercial acumen to develop long-term partnerships across the full drug development lifecycle from early development through clinical and commercial manufacturing.You will work closely with internal scientific and business development teams across the US and Europe, positioning Pharmaron as a trusted strategic partner and delivering tailored solutions that align with client needs.Key Roles and Responsibilities· Develop and strengthen strategic relationships with multinational pharmaceutical (Big Pharma) clients· Identify and drive growth opportunities across small molecule CMC services, including drug substance and drug product· Deliver against sales and revenue targets, contributing to overall business growth· Collaborate with global Business Development teams to define and execute account strategies· Lead and support proposal development (enquiry to contract), ensuring alignment with client requirements and internal capabilities· Partner closely with scientific and operational teams to deliver integrated, client-focused solutions· Identify and drive cross-selling opportunities across Pharmaron’s end-to-end service offering· Monitor market trends, competitor activity, and client pipelines to shape strategic direction· Support contractual and commercial discussions, including confidentiality agreements and key terms· Establish and lead governance frameworks with key clients, including regular operational and executive-level reviews· Act as an internal expert, contributing to capability development and strategic growth initiativesRequirements· PhD in Organic Chemistry or a related scientific discipline· Extensive experience (10+ years) within a Big Pharma environment, ideally in process chemistry, drug substance development, or CMC· Strong knowledge of the drug development lifecycle, particularly small molecule CMC· Proven track record in building strategic partnerships and delivering commercial results· Strong business acumen, with the ability to translate scientific expertise into client value· Experience working within matrix organisations and cross-functional teams· Excellent communication, negotiation, and stakeholder management skills· Ability to operate strategically while delivering measurable outcomesWhat We OfferAt Pharmaron, you will take on a high-impact, strategic role at the forefront of our growing CMC business. You will have the opportunity to shape long-term partnerships with leading pharmaceutical companies while working within a collaborative, global environment.We offer a competitive salary, comprehensive benefits, and the opportunity to contribute to a dynamic, fast-growing organisation where your expertise directly supports the delivery of innovative medicines. xrnqpay Why Should You Apply?· Play a key role in shaping strategic partnerships with global pharmaceutical leaders· Work at the intersection of science, strategy, and commercial growth· Be part of a fast-growing CRO with a strong global presence· Collaborate with experienced scientific and business leaders across regions· Contribute directly to the growth of Pharmaron’s integrated CMC offering Considering applying for this job Do not delay, scroll down and make your application as soon as possible to avoid missing out. Salary Competitive Frequency Annual Job Reference ukpharmaron/TP/142/693 Contract Type Permanent Contract Closing Date No expiry date Job Category Business Development & Marketing (BD) Division Business Development & Commercial Location Hoddesdon, United Kingdom Posted on 18 June, 2026