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Salary: up to £75,000 Cambridge, travel across the UK as needed Job Details Our client, an international consultancy business, currently have an opportunity for a Commercial Contract Manager, within a fast growing commercial department, this is a unique opportunity, a chance to be truly strategic and shape the future of the organisation. The company have a long and successful history of delivering large projects to various private and public sectors clients and are on a journey to change the way they do business – and looking for ambitious, commercially minded individuals to help them get to the next level! The role holder will have the opportunity to lead the commercial negotiation of new business with both new and existing clients and to shape the strategic direction of the function. You Will • Identify the risks, liabilities, and commitments of contractual agreements; ensure these are clearly understood and that the business fully appreciates any potential impact., • Review, draft, update and maintain contract documents, • Monitor and report performance and compliance against contractual obligations including commercial performance, financial management and contract management, • Monitor customer satisfaction, • Work with the contract delivery teams to ensure that the management of change request process and change implementation is carried out in line with the contracts., • Report on progress of change requests and projects, • Review contract performance, assessing commercial risks and ensuring appropriate steps are taken to manage the risk, • Prevent and resolve contractual disputes, • Assuring adherence to Group Commercial Policy, • Supporting the client engagement teams in all commercial aspects, post contract signature, to achieve the orders, profit and cash budget and overall management of the Client relationship., • Support the delivery streams who are responsible for the delivery of projects and provide clear direction working with the client engagement team. The Person • Experience of working in the civil nuclear industry would be advantageous, • growth minding – looking at maximising value and minimising risk, • Experience of working closely with finance, operations and technical specialists, • Good on both the legals and financials Please reach out to Casey Collins at , if interested.

About the Role Sequential is building a next-generation AI-driven discovery platform to identify and design novel functional actives, including peptides and complex ingredient systems. The platform integrates large-scale biological datasets (>50,000 samples and measurements) spanning multi-omics data, microbiome sequencing, clinical and real-world outcomes. Our goal is to translate biological signals into actionable compound discovery and optimisation, powering a pipeline across: Discovery → Prediction → Design → Validation • We are looking for a Senior Computational Biologist with ML Engineering background to help build, bridge, and functionalise the link between AI-powered biological discovery and real-world clinical outcomes. This role sits across biological discovery and scalable ML engineering. You will own key parts of the end-to-end architecture from data to model to evaluation to deployment, and work closely with ML engineers and software engineers to productise the platform into client-ready outputs. This is a senior role with significant autonomy and technical ownership. The Data You Will Work With The platform is built on a growing dataset of >50,000 biological samples and measurements, including paired pre- and post-treatment observations. The data includes multiple modalities such as microbiome sequencing (16S rRNA sequencing, ITS sequencing, shotgun metagenomics), Multi-omics (proteomics, lipidomics, metabolomics), Clinical and observational data (treatment exposure, formulation and ingredient combinations, clinical outcomes, patient metadata). Datasets include longitudinal measurements, enabling analysis of biological response to interventions (e.g., ingredient exposure, treatment, formulation). 1. Build the discovery engine (data → signal → candidate) ● Develop models that identify novel functional actives from multi-omic datasets ● Detect patterns in biological signatures that correlate with clinical outcomes (e.g., inflammation reduction, microbiome restoration, barrier repair, malodour reduction) ● Create robust feature representations from: o microbiome sequencing (16S/ITS/shotgun) o gene expression / transcriptomics o lipidomics / proteomics / metabolomics o clinical metadata and response data o SNP and risk features (where relevant) 2. Predict mechanism + response ● Build predictive models for: o molecule–microbe interactions o molecule–host pathway effects o omics signature prediction o clinical response forecasting o safety and developability scoring ● Translate model outputs into interpretable mechanistic narratives for R&D teams and external partners. 3. Design and optimise functional complexes ● Implement multi-objective optimisation and scoring frameworks to balance: o efficacy / predicted response o safety and stability constraints o manufacturability and cost o regulatory feasibility ● Support generation of: o intelligent ingredient complexes o repurposed peptides o newly discovered natural peptides 4. Productionise the AI product launch ● Build end-to-end ML pipeline covering ingestion, training, evaluation and deployment ● Develop APIs/services to serve predictions and ranked candidates into internal tools and client outputs ● Create evaluation harnesses to compare predicted vs. observed validation outcomes ● Implement monitoring and governance: drift, data quality checks, model versioning, auditability 5. Collaborate cross-functionally ● Work closely with biology, formulation, and clinical teams to design experiments and validation loops ● Partner with product and commercial teams to shape “client-ready” deliverables (e.g., ranked actives, evidence packs, scientific dossiers) ● Lead and /or partner with ML and software teams to define ownership boundaries code reviews norms, and the path fron prototype to a maintained service. 12-Month Mission Month 0–3: Foundation & Proof of Concept ● Establish harmonised datasets and core data pipelines with dataset versioning, documented schemas, and baseline QC checks ● Deliver feasibility screening models for active discovery with an agreed split strategy (sample, cohort, and time splits) and reporting baseline ranking metrics (e.g., hit-rate@K, NDCG@K) ● Build initial predictive baselines with clear metrics Month 3–6: Modelling & Optimisation ● Implement multi-criteria scoring + optimisation with a defined objective, weighting strategy, and ablation plan ● Extend predictive models and improve candidate ranking performance ● Develop reproducible experiment tracking and evaluation workflows Month 6–9: Advanced Validation ● Compare predictions against real validation outputs and refine models ● Improve robustness, interpretability, and governance ● Deliver a performance report suitable for internal and external stakeholders Month 9–12: Client Readiness & Pilot Launch ● Finalise v1.0 AI product outputs (ranked candidates + evidence summaries) ● Support pilot client projects and accelerate validation turnaround time ● Contribute to the first commercial-ready “hero” functional complex pipeline What we’re looking for Essential ● Strong Python and experience building ML systems end-to-end with evidence (links to shipped projects, tools, or repos) ● Proven ability to work with large, messy real-world datasets and to define leakage-safe validation splits (e.g., sample, time, cohort) ● Practical knowledge of ML evaluation, validation strategy, and failure modes including error analysis and iteration planning ● Experience with model development using PyTorch / TensorFlow / JAX ● Ability to communicate clearly across technical + scientific stakeholders ● Strong experience leading or coordinating cross-functional teams, and thinking strategically across product and science (prioritisation, tradeoffs, and shipping) ● Comfort deploying models (batch + real-time inference) into production environments or owning the handoff to engineering with clear interfaces Strongly preferred • Experience with biological or high-dimensional scientific datasets (omics, imaging, microbiome, clinical), • Experience with multi-modal learning, embeddings, or representation learning, • Familiarity with optimisation / ranking / multi-objective scoring systems, • Interest in mechanism-driven modelling and scientific interpretability, • Foundation model experience (LLMs and/or biological foundation models) with proof (fine-tuning/adapters or applied FM pipelines, plus how it was evaluated), • A strong portfolio of tool or pipeline development (internal platforms, evaluation harnesses, reproducible workflows) Nice to have • Experience building developer-friendly tooling: CLIs, dashboards, APIs, or reusable libraries used by other scientists/engineers, • Some front-end/product sense (you care about shipping usable tools, not just notebooks), • Experience with causal inference, Bayesian methods, or mechanistic simulation

Join Our Inclusive Learning Community as a Communication Support Worker (CSW) Are you passionate about supporting Deaf learners and fluent in British Sign Language (BSL)? Do you want to make a real difference in a vibrant, inclusive college environment? If so, we would love to hear from you! We’re looking for a dedicated Communication Support Worker (CSW) to join our team on a full-time, term-time basis (37 hours/week). In return, you’ll receive a competitive salary of £21,890 per annum - £23,593 per annum (equivalent to a full year salary of £25,192 - £27,152 per annum), plus a fantastic range of staff benefits. Why Join us? We’re more than just a college—we’re a community. With campuses in Cambridge and Huntingdon, we offer state-of-the-art facilities, a dynamic learning environment, and a strong reputation for excellence. We’re proud to be recognised with Investors in People Gold status, reflecting our commitment to staff development and wellbeing. What You’ll Be Doing As a CSW, you’ll play a vital role in helping Deaf and hard-of-hearing students thrive. You’ll: Work closely with teaching staff to support learners across a range of vocational subjects Promote independence, confidence, and inclusion Help students access the curriculum and reach their full potential Use your initiative and empathy to support learners in a flexible, responsive way ✅ What We’re Looking For We’re seeking someone who: Holds a Level 3 qualification in BSL (Signature, CACDP, SEG, or Scottish equivalent) Ideally has a formal CSW qualification Has GCSE Grade C or equivalent in English and Maths Brings experience working with Deaf learners or those with SEND Is compassionate, adaptable, and committed to inclusive education Perks & Benefits Here’s just a taste of what you’ll enjoy as part of our team: Generous holidays: 27 days + bank holidays + Christmas closure Excellent pension schemes (TPS 28.68%, LGPS 20.10%) Free gym membership & discounted fitness classes Discounted or fully funded college courses BUPA health cash plan & occupational health services Subsidised on-site Costa, Starbucks & restaurants Free parking with EV charging ️ High street & online discounts with (email address removed) Free 24/7 counselling via Employee Assistance Programme Ongoing training & development opportunities In return for the above you can expect to receive: A dedicated team of consultants available 24/7 to help you with the easy onboarding process Guaranteed Payment Scheme CPD Courses and certificates as part of the My-Progression Channel Market leading rates of pay TeacherActive Referral Scheme – Receive up to £100 when you refer a friend Our staff are paid on a PAYE basis, so you can rest assured that you’re paying the right level of TAX and National Insurance and there’s no messing around with admin charges coming out of your hard earned cash. If you are interested in this position, then click ‘APPLY NOW’ and I will be in touch regarding this fantastic opportunity. EMAIL : (url removed) CONTACT NUMBER : All applicants will be contacted to discuss suitability and then invited to register with TeacherActive. Registration involves an enhanced DBS check, ID checks and will require you to supply good professional references. We pride ourselves on excellent service. We can provide a wide range of opportunities in schools and other educational institutions, with good rates of pay, at times to suit your needs. Regular external audits have shown repeatedly that our standards are exceptional. We are passionate about finding the right staff for each environment. TeacherActive is an equal opportunities employer, and operates as an Employment Business in providing temporary or contract job-seeking services