Research Scientist, Assay Development
22 days ago
Boston
Job Description About GrapheneDx: GrapheneDx is a new diagnostics technology company with a mission to transform consumer diagnostics. Our employees gain experience in a multidisciplinary, fast-paced start-up and have ample opportunities to acquire new skills, engage with emerging technologies, and collaborate closely with an accomplished team, all within in a supportive and energetic environment. GrapheneDx offers a competitive compensation package including base salary, performance bonuses, paid time off, health and dental benefits, and excellent growth opportunities. GrapheneDx is seeking a Research Scientist who will apply their expertise to advance our R&D efforts in biosensor development and communicate valuable insights to a highly collaborative and dynamic team. Summary: The Research Scientist in Assay Development will design and execute experiments to functionalize sensors with nucleic acid or antibody probes for biomarker detection, contributing to the development of a groundbreaking, point-of-care diagnostic platform. Collaborating closely with a senior scientist and a cross-functional team of materials scientists, electronics engineers, and data scientists, this role drives forward a disruptive diagnostic technology poised to redefine the field. Key Duties and Responsibilities: • Drive the development of a novel GFET-based point-of-care diagnostic platform., • Design, execute, and optimize experiments for biomarker detection, including feasibility, pilot, and process optimization studies., • Perform data analysis, critically interpret results, and prepare reports and presentations tailored to the needs and expertise of internal and external stakeholders., • Collaborate with a cross-functional team of scientists and engineers to design experiments aligned with R&D objectives, ensuring sensor technology integration into scalable diagnostic solutions., • Document, refine, and optimize protocols, creating actionable plans to improve processes and advance R&D milestones, • Ph.D. in Biochemistry, Biology, Chemistry, Electrochemistry, Biophysics, or a related discipline, or a Master’s degree with 1-5 years of relevant academic or industry experience., • Proven experience in creating and developing biosensor immunoassays and/or nucleic acid detection assays through probe hybridization., • Strong problem-solving skills, with the ability to identify challenges and propose alternative approaches., • Excellent organizational and analytical skills, including the ability to summarize and translate data into actionable plans., • Effective oral and written communication skills to convey technical information to both supervisors and team members. Desirable Experience: • Experience with non-optical-, electrical-, or electrochemical-based sensors, especially graphene-based or carbon nanotube-based sensing platforms., • Experience functionalizing GFETs with biological probes, such as nucleic acids or antibodies, to enable biomarker detection., • Experience defining and improving biosensor performance metrics, such as sensitivity, specificity, limit of detection (LOD), and other industry-standard used to quantify biosensor efficacy and reliability., • Proficiency in coding or data visualization using Python, Origin, and/or Minitab for data analysis and visualization., • Working knowledge of statistical analysis and design of experiments., • Ability to coordinate effectively across multiple functional areas., • Highly motivated and adaptable, with the flexibility to thrive in a dynamic and interdependent environment.