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Senior Scientist I - Characterisation | CMC - Oxford Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industrys most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.To characterise the companies biotherapeutic recombinant T-cell receptor based and related molecules using a wide variety of protein characterisation and mass spectrometry methods. To contribute to the development of characterisation methods for the companys biopharmaceutical products, including peptide mapping (LC-MS/MS) and intact mass spectrometry analysis. KEY RESPONSIBILITIES* Supporting drug substance and drug product impurity characterisation and identification* Performing protein sequence and post translational modification identification, including glycosylation analysis. * Supporting drug substance and drug product process development by performing characterisation of process intermediates * Contribute to the Development of characterisation methods of ImmTAX and other products, including peptide mapping (LC-MS/MS) and intact mass analysis * Designing and carrying out biochemical characterisation, chemical stability and comparability studies of biologics/drug products. * Contribute to writing study protocols and reports.* Independently testing and, increasingly, leading lines of investigation. Proposing new experiments based on emerging data and other related information. Providing support on technical aspects to others. * Priorities: establishing priorities for own work and team-based projects; making decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance. * Technical Knowledge: sharing knowledge with the wider team and, across departments representing the department. May also act as a mentor to other colleagues, sharing scientific knowledge. Providing analysis of new techniques and theories from outside the Company to advance the way the company works; sharing these with leaders across the department. * Laboratory records: ensuring that all records and information are up to date, on time and recorded to the correct standard. Supporting and encouraging others to achieve this.* Laboratory equipment: providing technical guidance to others within the team on how to use equipment most effectively.* Reporting: communicating and presenting research findings at meetings with colleagues, senior management and partners.* Adhere to safe working practices in laboratories according to Immunocore EHS policies.PERSON SPECIFICATIONExperience & knowledgeEssential* Experience in development of HPLC based peptide mapping methods and mass spectrometric characterisation of recombinant proteins or antibodies. * Experience of glycosylation analysis of recombinant proteins or antibodies.* Independently coordinated extensive testing of protein biomolecules.* Experienced in the characterisation of proteins expressed in both microbial and mammalian systems.* Understanding of expected post-translational modifications in biological systems.* Worked in a bench-based biopharmaceutical laboratory environment. * Established as an expert amongst peers in one or more of the following areas: o electrophoretic o chromatographic o mass spectrometry* Experienced in assay development * Familiar with biopharmaceutical stability study principles and interpretation thereof* Worked and contributed actively in a diverse team environment* Proposed and driven changes in working practices that have improved efficiency, supported teams through adoption and change* Presented detailed scientific findings and papers to internal and external audiencesDesirable * Experience of glycosylation analysis of recombinant proteins or antibodies* Experience with late stage/commercial biopharmaceutical assay development and characterisation * Familiar with the principles of Good Manufacturing Practise (GMP)* Presented at external conferences* Led a small project team, formally or informally, through a change in practice including project management * Understanding of analytical requirements to support materials for use in clinical trialsEducation & qualifications* Essential: BSc. Or MSc. in biochemistry, biotechnology or related discipline* Desirable: PhD in related discipline

Childrens Senior Support Worker Bicester, Oxfordshire OX26 Employer: Homes2Inspire (part of Shaw Trust Group) Contract: Full-time, Permanent, 40 hours per week Salary: £30,196 - £31,259 per annum (£14.52 - £15.03 per hour) + sleep-in allowance (£46.01 per sleep) + attendance bonus About Homes2Inspire Homes2Inspire are one of the UKs leading providers of childrens homes, caring for over 150 children across 56 homes and 2 semi-independent leaving care facilities. We are proud to be part of the Shaw Trust Group, a charity dedicated to transforming lives across the UK. About the Home: Harris House is a 2 bedded childrens residential home in Bicester, Oxfordshire OX26. It provides a safe, nurturing, and supportive environment by offering emotional and practical support to help children develop life skills and build confidence. Vacancy: As a Senior Support Worker, you will play a key role in supporting the management team and ensuring the smooth running of each shift. You will take responsibility for leading the team, delegating roles and responsibilities to support workers, and maintaining accurate records at all times Effective communication skills, along with the ability to build relationships with others is vital! We are looking for an individual who can lead by example, uphold standards, and ensure that the safeguarding of children and young people underpins all decisions made. As a Senior Support Worker, you will: Safeguard and promote the wellbeing of young people in our care. Support with daily routines, household tasks, and meal preparation. Encourage participation in community activities and hobbies. Transport young people to school, medical appointments, and activities. Act as a positive role model, setting clear boundaries and building trust. Help young people develop life skills, including managing finances. Maintain accurate records and paperwork. Work flexibly, including evenings, weekends, bank holidays, and sleep-ins (12 per week). What Youll Bring Compassion, patience, and a genuine desire to make a difference. Strong communication and interpersonal skills. Ability to remain calm in challenging situations. Experience of working with behaviours that challenge Minimum 1 years' experience working with children and young people QCF Level 3 in Childrens Residential Childcare or an equivalent qualification or be studying towards. Honesty, empathy, and a positive role model. What We Offer Competitive salary (£30,196 - £31,259 per annum). Sleep-in allowance (£46.01 per sleep). Attendance bonuses (up to £1,400 per year). Overtime opportunities available. Comprehensive training and career development pathways. Generous annual leave, with option to purchase 5 extra days. Employee Assistance Programme (EAP) and wellbeing support. Unum Healthcare - App-based access to healthcare reimbursements, mental health support, remote GP, and wellbeing perks Aviva Digicare - Access free healthcare services including Digital GP consultation, Annual Health Check and Mental Health Assessments Refer a Friend bonus Discounts on shopping, cinema, holidays, plus Blue Light Card access. Cycle to Work scheme. Subsidised days out with young people. Recognition awards for long service and attendance. Meals included during shifts . Important Information Drivers with a full UK drivers license are preferred. Sleep-ins are required (average 12 per week). We cannot offer sponsorship . All successful candidates will undergo safer recruitment checks in line with Ofsted requirements. How to Apply If youre looking for a new job in Bicester, Oxfordshire OX26 and are passionate about making a positive impact in young peoples lives, apply today! TPBN1_UKTJ

Wrightbus Refurbishment is a forward-thinking after sales division of Wrightbus, dedicated to revolutionizing public transportation with environmentally friendly technology. Our mission is to provide efficient, sustainable, and innovative solutions to reduce our carbon footprint. Wrightbus Refurbishment supports Wrightbus as the fastest growing manufacturing company in Europe. We are therefore recruiting a Paint Sprayer Supervisor for the Bicester, Oxfordshire site. The successful candidate will be responsible to lead and supervise the paint spraying team in delivering high-quality finishes on Wrightbus vehicles, ensuring all work meets company standards, customer specifications, and production schedules. The supervisor will drive performance, maintain safety and compliance, and support continuous improvement across the paint shop. The Role: Supervise daily operations of the paint spraying team, ensuring productivity and quality targets are met. Allocate tasks and manage workflow to align with production schedules. Conduct quality checks on completed work, ensuring adherence to paint specifications and finish standards. Train, mentor, and support paint sprayers to develop skills and maintain high performance. Monitor and enforce health & safety procedures, including PPE usage and safe handling of materials. Liaise with production planners and other supervisors to coordinate vehicle flow and resolve bottlenecks. Maintain accurate records of paint usage, job completion, and team performance. Identify and implement process improvements to enhance efficiency, reduce waste, and improve finish quality. Ensure compliance with environmental regulations and company policies regarding paint materials and disposal. Support root cause analysis and corrective actions for paint-related defects or rework. The Requirements: Proven experience in automotive or industrial paint spraying, ideally in a supervisory or team lead role. Strong understanding of paint application techniques, surface preparation, and finishing standards. Ability to read and interpret technical drawings and paint specifications. Excellent leadership and team management skills. Strong attention to detail and commitment to quality. Good communication and interpersonal skills. Knowledge of health & safety regulations relevant to paint spraying and chemical handling. Ability to work under pressure and meet tight deadlines. Proficient in basic IT systems (e.g., job tracking software, email, spreadsheets). The Benefits: Medicash Scheme Discount with local businesses and high street retailers Career Progression Note: This job description will be subject to review in the light of changing circumstances and may include other duties and responsibilities, as may be determined in consultation with the jobholder. It is not intended to be rigid and inflexible but should be regarded as providing guidelines within which the individual works. Wrightbus is committed to equality of opportunity and to selection on merit. TPBN1_UKTJ

Controls & Instrumentation Technician – Power Station Up to circa £47,000+ benefits + shift allowance Bicester, Oxfordshire MC Technical Recruitment are recruiting for a Controls and Instrumentation Technician to join an energy from waste power station in the Bicester area in Oxfordshire. The C&I Technician will form part of the maintenance team and will be responsible for conducting planned and reactive maintenance work on the sites instruments and control systems to ensure maximum plant availability. Reporting to the EC&I Engineer, responsibilities will include: Fault finding, repair work and planned and unplanned maintenance on all C&I assets to maximise plant availability. This includes pressure, level, temperature and flow sensors, control systems and some electrical equipment such as motors and variable speed drives Collaborating with other Technicians and Engineers to ensure an accurate daily schedule is produced and worked to Work with the site engineering team on plant improvement projects and upgrades Assisting during site outages / shutdowns when required Maintaining accurate maintenance records using the site CMMS The ideal candidate will have: An apprenticeship in electrical/instrumentation engineering or similar A relevant engineering qualification at HNC/ONC level or similar Proven hands-on maintenance experience across control and instrumentation maintenance in a relevant engineering environment – power plant, refinery, paper mill, steel works, chemical, water treatment etc. Experience using CMMS (Computerised Maintenance Management Systems) Knowledge of relevant legislation e.g., health and safety and environmental etc. Salary & benefits This is an exciting opportunity to join the growing energy from waste sector with: A competitive basic salary up to circa £47,000 Shift allowance A site bonus Company pension Overtime If you are interested in this role, please apply via the link below or contact Machaela at MC Technical Recruitment on 01489 533 030 / for a confidential chat. TPBN1_UKTJ

Key responsibilities include providing expert guidance, overseeing records lifecycle processes, and supporting projects that integrate records management into new systems. Ideal candidates will have experience in records management services and strong organisational skills in a digital environment,

Working closely with the Records Lead, you will develop and improve records management practices across the organisation, provide training to staff, and ensure compliance with legislation such as the Public Records Act, Legal Deposit Libraries Act, and UK GDPR. This role would suit someone with a st

We also transport, store and install precious art collections and keep company data and records safe, yet accessible.

A public sector regulatory body in the UK is seeking a Records Management Senior Adviser to ensure compliance with records management legislation. Ideal candidates will possess a relevant qualification and experience in records management, particularly within the public sector.

An independent regulatory body in the UK is seeking a Records Management Senior Adviser to ensure compliance with legislative requirements for records management. The ideal candidate will have a strong background in records management, excellent organizational skills, and the ability to communicate

A global logistics company is seeking a detail-oriented Marketing Analyst for its EMEA Marketing team in the United Kingdom.The role involves analyzing marketing channel performance, compiling monthly reports, and collaborating with teams to optimize digital campaigns.Ideal candidates should have ov

Working closely with the Records Lead, you will develop and improve records management practices across the organisation, provide training to staff, and ensure compliance with legislation such as the Public Records Act, Legal Deposit Libraries Act, and UK GDPR. Experience in records management and d

We also transport, store and install precious art collections and keep company data and records safe, yet accessible.

Fixed Term until 13 April 2026.Interviews will be held week commencing 9 February 2026.An exciting opportunity has arisen to join our successful, dynamic and supportive school team within Eastertoun Primary School nursery class.The school is a non-denominational primary with 8 classes and a nursery

A global logistics company in the UK is looking for a Fine Art Warehouse Manager.The role involves supervising warehouse technicians, ensuring the safety and care of priceless artworks during handling, and complying with health and safety regulations.Ideal candidates will have experience in installa

Please note: PVG member’s records are constantly updated with any new vetting information that arises.

As a BANK Residential Care Worker, you will be emotionally strong and driven to make a difference day to day.Most importantly, you will get to really understand our children and their backgrounds, making sure that their needs are at the centre of everything we do.You will be approachable and detail

Maintain records as required at the project under the direction of the Support Workers/ management. Participate in the support planning and risk management, as facilitated by the lead Support Worker.

To maintain accurate notes and records as and when required.

Working in our Childrens Homes means being a part of a young persons day to day life.This means being there for the highest highs and lowest lows.Our support workers enable our young people to get their childhood back and create pathways to become well rounded adults an incredibly rewarding role.

As the BANK Residential Care Worker, you will be emotionally strong and driven to make a difference day to day.Most importantly, you will get to really understand our children and their backgrounds, making sure that their needs are at the centre of everything we do.You will be approachable and deta

This is a full-time on-site role for a Medical Receptionist with leadership and management skills. Electronic diary management (including appointment scheduling). Attendance at all mandatory and statutory training requirements as indicated by senior management/directors.

To maintain accurate notes and records as and when required.

The National Autistic Society is committed to safeguarding and promoting the welfare of all children and adults who use our services.Successful applicants will be required to complete the relevant safeguarding checks.The National Autistic Society helps create a world that works for autistic people,

Make a Real Difference – Become a Support Worker!.Are you someone who thrives on helping others unlock their potential? Do you believe everyone deserves the chance to live independently and with dignity? If so, they’d love to hear from you!.They’re on the lookout for a compassionate, proactive

Part time, 16 hours per week - flexible shifts, including weekends and sleep-ins.Our client are looking for someone to join their friendly team in Hazlemere and make a real difference every day.You will support two ladies in their own home, helping them live happy, safe, and independent lives.One la

The National Autistic Society is committed to safeguarding and promoting the welfare of all children and adults who use our services.Successful applicants will be required to complete the relevant safeguarding checks.The National Autistic Society helps create a world that works for autistic people,

Offer line management, coaching and supervision for designated staff. Experience of risk management and safeguarding. Effective time management, planning and organisational skills.

Full or Part Time opportunities available.Once 6-month probation is passed).Additional payments for night shifts (£12 per night - £55 for sleep-in).Have you worked in an adult social care or nursing setting?.Experience of being a team leader or have at least 1 year of care experience?.Do

The National Autistic Society is committed to safeguarding and promoting the welfare of all children and adults who use our services.Successful applicants will be required to complete the relevant safeguarding checks.Join Us as a Bank Support Worker.The National Autistic Society helps create a world

Health plan • Discounts in high street shops including technology and cycle to work scheme • No weekend working • Casual dress code • Local and national training opportunities.The organisation, a place to be yourself.Do you want to work for a company that encourages you to bring your whole s

Ability to maintain accurate records and complete clear written reports. IT literacy with confidence using Microsoft Office and case management systems. An engaging opportunity supporting vulnerable adults within dispersed accommodation, delivering person-centred case management, safeguarding, suppo

The National Autistic Society is committed to safeguarding and promoting the welfare of all children and adults who use our services.Successful applicants will be required to complete the relevant safeguarding checks.The National Autistic Society helps create a world that works for autistic people,

As a Bank Receptionist at a Barchester care home, you'll provide the warm welcome that helps to make sure every resident and visitor feels at home with us.As the first point of contact for almost everyone who comes to the home, you'll have a vitally important part to play in creating a positive and

If you take pride in delivering excellent service and keeping processes running efficiently, this opportunity could be an excellent next step.Our client is currently looking for an.This position will play a vital role in customer service and the organisational efficiency of the company.Duties will i

Full time, 39 hours per week – flexible rota including split shifts, sleep-ins, waking nights and weekends.Are you ready to make a real difference every single day? As a Support Worker, you will support people with learning disabilities, autism and mental health needs to live happy, safe and i

We are looking to add Relief Support Workers to our team in Sunderland.Our service supports individuals with learning disabilities and mental health support needs related to communication Committed to helping our clients recognize their strengths, abilities and personal resources, we seek warm, cari

Part time, 16 hours per week - flexible shifts, including weekends and sleep-ins.Our client are looking for someone to join their friendly team in Hazlemere and make a real difference every day.You will support two ladies in their own home, helping them live happy, safe, and independent lives.One la

The successful applicant will be required to undergo an enhanced disclosure from the Criminal Records Bureau.

Home Support Worker – x2 positions.Working between Amberley Nursing Home, Calow, Chesterfield and Fisher Close,.We have a fantastic opportunity for a Home Support Worker to join our teams in Calow, Chesterfield.We have a full time position available.Shifts will be based on rota and will include mo

We are looking for a friendly Support Worker to provide personalised support to adults with a learning disability living at our supported living service in Barrow, Cumbria.You will have a can-do approach with the acknowledgement of positive behaviour support to ensure all service users can enjoy the

We are seeking a warm, caring senior support worker to provide personalised care and support in, our extra care services in Tameside, which enables older people to maintain an active and independent lifestyle.This service enables older people to maintain their wellbeing and to enjoy an active and i

Residential Childcare Support Worker.FTE) per annum with the potential to earn up to £15,647.FTE) per annum with the potential to earn up to £16,229.

At Achieve together, we strive to support and inspire the people we care for to give them the resources, skills and confidence to live their lives independently, and to the fullest.Without our incredible team of Support Workers, we simply wouldn't be who we are today.We're always looking for hard-wo

Waking Night Support Worker Bicester, Oxfordshire, OX26.Homes2Inspire (part of Shaw Trust Group).Full-time, Permanent, 40 hours per week.Homes2Inspire are one of the UKs leading providers of childrens homes, caring for over 150 children across 56 homes and 2 semi-independent leaving.

Care Assistant / Support Worker - Joint Community Rehabilitation (JCR).Lewes, Haven, High Weald, Eastbourne, Hailsham, Seaford.Permanent- Pro-rata | Flexible shifts | 4-week rota.Every other weekend | Shifts: 7am-12pm, 1pm-5pm, 6pm-10pm.Joint Community Rehabilitation (JCR).JCR provides up to 6 weeks

You will have excellent line management support and development from a CQC registered manager.

At Achieve together, we strive to support and inspire the people we care for in order to give them the resources, skills and confidence to live their lives independently, and to the fullest.Without our incredible team of Support Workers, we simply wouldn't be who we are today.We're always on the hun

Elwood Recruitment are looking for Support Workers in Barnet * * Do you have experience supporting adults with disabilities and autism? * Do you live in Barnet or the surrounding areas? * Do you have a passion for supporting vulnerable adults? * Do you have a minimum of