Analyst II – LC-MS / Peptide Analysis
5 days ago
North Charleston
NxtGen is a growing cGMP analytical testing laboratory specializing in peptide and protein characterization. We are seeking an Analyst II to support routine analytical testing with a focus on LC-MS and peptide analysis. This role is ideal for candidates with hands-on experience who can operate independently and contribute to data quality, method execution, and laboratory efficiency. Key Responsibilities • Perform routine and non-routine LC-MS analysis (Agilent systems preferred) for peptide identification, characterization, and impurity profiling, • Conduct HPLC/UPLC testing for purity, related substances, and method-based analysis, • Prepare samples, solvents, calibration standards, and system suitability solutions, • Process, review, and verify analytical data for accuracy and completeness, • Generate and review analytical reports in accordance with internal procedures, • Perform basic troubleshooting of LC-MS and chromatographic systems, • Support method transfer, verification, and routine method execution, • Assist with investigations (e.g., OOS/OOT) and deviation documentation as needed, • Support endotoxin (LAL) and sterility testing as required, • Maintain complete and compliant documentation in accordance with GDP and ALCOA+, • Follow SOPs, cGMP/GLP requirements, and safety procedures, • Maintain a clean, organized, and audit-ready laboratory environment Qualifications • Bachelor or Master’s degree in Chemistry, Biochemistry, or related field, • 2–5 years of analytical laboratory experience, • Hands-on experience with LC-MS and HPLC/UPLC systems (Agilent preferred), • Experience with peptide analysis strongly preferred, • Familiarity with data processing and chromatographic/mass spectral interpretation, • Strong attention to detail and documentation skills Why Join NxtGen • Work in a peptide-focused analytical laboratory with advanced instrumentation, • Expand expertise in LC-MS, impurity profiling, and peptide characterization, • Be part of a growing, collaborative, and fast-paced environment, • Contribute to cGMP-compliant testing for commercial and research clients Working Conditions • Environment: Laboratory setting with exposure to chemicals, biological materials, and laboratory equipment., • Schedule: Monday – Friday, 7:00 AM – 3:30 PM., • Location: North Charleston, SC., • PPE: Required use of personal protective equipment (lab coat, gloves, safety glasses). Equal Employment Opportunity NxtGen is a Disabled and Veteran Equal Employment Opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. Benefits • Competitive salary, • Health, dental, and vision insurance, • 401(k) with company match, • Paid time off and holidays, • Employee Purchase Program