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About the Role Sequential is building a next-generation AI-driven discovery platform to identify and design novel functional actives, including peptides and complex ingredient systems. The platform integrates large-scale biological datasets (>50,000 samples and measurements) spanning multi-omics data, microbiome sequencing, clinical and real-world outcomes. Our goal is to translate biological signals into actionable compound discovery and optimisation, powering a pipeline across: Discovery → Prediction → Design → Validation • We are looking for a Senior Computational Biologist with ML Engineering background to help build, bridge, and functionalise the link between AI-powered biological discovery and real-world clinical outcomes. This role sits across biological discovery and scalable ML engineering. You will own key parts of the end-to-end architecture from data to model to evaluation to deployment, and work closely with ML engineers and software engineers to productise the platform into client-ready outputs. This is a senior role with significant autonomy and technical ownership. The Data You Will Work With The platform is built on a growing dataset of >50,000 biological samples and measurements, including paired pre- and post-treatment observations. The data includes multiple modalities such as microbiome sequencing (16S rRNA sequencing, ITS sequencing, shotgun metagenomics), Multi-omics (proteomics, lipidomics, metabolomics), Clinical and observational data (treatment exposure, formulation and ingredient combinations, clinical outcomes, patient metadata). Datasets include longitudinal measurements, enabling analysis of biological response to interventions (e.g., ingredient exposure, treatment, formulation). 1. Build the discovery engine (data → signal → candidate) ● Develop models that identify novel functional actives from multi-omic datasets ● Detect patterns in biological signatures that correlate with clinical outcomes (e.g., inflammation reduction, microbiome restoration, barrier repair, malodour reduction) ● Create robust feature representations from: o microbiome sequencing (16S/ITS/shotgun) o gene expression / transcriptomics o lipidomics / proteomics / metabolomics o clinical metadata and response data o SNP and risk features (where relevant) 2. Predict mechanism + response ● Build predictive models for: o molecule–microbe interactions o molecule–host pathway effects o omics signature prediction o clinical response forecasting o safety and developability scoring ● Translate model outputs into interpretable mechanistic narratives for R&D teams and external partners. 3. Design and optimise functional complexes ● Implement multi-objective optimisation and scoring frameworks to balance: o efficacy / predicted response o safety and stability constraints o manufacturability and cost o regulatory feasibility ● Support generation of: o intelligent ingredient complexes o repurposed peptides o newly discovered natural peptides 4. Productionise the AI product launch ● Build end-to-end ML pipeline covering ingestion, training, evaluation and deployment ● Develop APIs/services to serve predictions and ranked candidates into internal tools and client outputs ● Create evaluation harnesses to compare predicted vs. observed validation outcomes ● Implement monitoring and governance: drift, data quality checks, model versioning, auditability 5. Collaborate cross-functionally ● Work closely with biology, formulation, and clinical teams to design experiments and validation loops ● Partner with product and commercial teams to shape “client-ready” deliverables (e.g., ranked actives, evidence packs, scientific dossiers) ● Lead and /or partner with ML and software teams to define ownership boundaries code reviews norms, and the path fron prototype to a maintained service. 12-Month Mission Month 0–3: Foundation & Proof of Concept ● Establish harmonised datasets and core data pipelines with dataset versioning, documented schemas, and baseline QC checks ● Deliver feasibility screening models for active discovery with an agreed split strategy (sample, cohort, and time splits) and reporting baseline ranking metrics (e.g., hit-rate@K, NDCG@K) ● Build initial predictive baselines with clear metrics Month 3–6: Modelling & Optimisation ● Implement multi-criteria scoring + optimisation with a defined objective, weighting strategy, and ablation plan ● Extend predictive models and improve candidate ranking performance ● Develop reproducible experiment tracking and evaluation workflows Month 6–9: Advanced Validation ● Compare predictions against real validation outputs and refine models ● Improve robustness, interpretability, and governance ● Deliver a performance report suitable for internal and external stakeholders Month 9–12: Client Readiness & Pilot Launch ● Finalise v1.0 AI product outputs (ranked candidates + evidence summaries) ● Support pilot client projects and accelerate validation turnaround time ● Contribute to the first commercial-ready “hero” functional complex pipeline What we’re looking for Essential ● Strong Python and experience building ML systems end-to-end with evidence (links to shipped projects, tools, or repos) ● Proven ability to work with large, messy real-world datasets and to define leakage-safe validation splits (e.g., sample, time, cohort) ● Practical knowledge of ML evaluation, validation strategy, and failure modes including error analysis and iteration planning ● Experience with model development using PyTorch / TensorFlow / JAX ● Ability to communicate clearly across technical + scientific stakeholders ● Strong experience leading or coordinating cross-functional teams, and thinking strategically across product and science (prioritisation, tradeoffs, and shipping) ● Comfort deploying models (batch + real-time inference) into production environments or owning the handoff to engineering with clear interfaces Strongly preferred • Experience with biological or high-dimensional scientific datasets (omics, imaging, microbiome, clinical), • Experience with multi-modal learning, embeddings, or representation learning, • Familiarity with optimisation / ranking / multi-objective scoring systems, • Interest in mechanism-driven modelling and scientific interpretability, • Foundation model experience (LLMs and/or biological foundation models) with proof (fine-tuning/adapters or applied FM pipelines, plus how it was evaluated), • A strong portfolio of tool or pipeline development (internal platforms, evaluation harnesses, reproducible workflows) Nice to have • Experience building developer-friendly tooling: CLIs, dashboards, APIs, or reusable libraries used by other scientists/engineers, • Some front-end/product sense (you care about shipping usable tools, not just notebooks), • Experience with causal inference, Bayesian methods, or mechanistic simulation

Description Join us, be part of more. We're so much more than an energy company. We're a family of brands revolutionising how we power the planet. We're energisers. One team of 21,000 colleagues that's energising a greener, fairer future by creating an energy system that doesn't rely on fossil fuels, whilst living our powerful commitment to igniting positive change in our communities. Here, you can find more purpose, more passion, and more potential. That's why working here is #MoreThanACareer. We do energy differently - we do it all. We make it, store it, move it, sell it, and mend it. We have a great opportunity for a Franchise License Manager. To manage and maintain the franchise framework of documents (the 'Franchise System') that define the franchising requirements, including any external accreditations and governance of license renewals and non-compliance of license obligations. This role will include frequent national travel. About the role: • Manage the franchise licence agreements, making amendments as required and ensuring agreements are issued on time, • Manage the licence renewals process, preparing and collating evidence to support renewal / non-renewal, • Ownership of the remedial action process where licence conditions are not met (PILs and Breaches) maintaining accurate records, including corrective action(s) required, timeframe for remediation and monitoring remediation, • Progress remedial actions where appropriate, engaging the relevant legal bodies, • Management of ISO accreditations including audits (internal and franchise) to maintain accreditation, • Management of subscriptions to professional bodies through evaluation of business case for membership, • Owning the Franchise Operations Manual and ongoing maintenance as a key legal document allied to the Franchise Agreement, • Is hyper-aware of changes in the external environment and is able to articulate what those mean for the customer and the team, adapting accordingly, • Enables agility throughout the organisation, • Prioritises decisions based on solving customer problems and improving the customer experience, in cognisance of commercial parameters, • Implements new ways of working that meet customers' needs and promotes customer centricity as a critical value, • Builds diverse capability across the organisation and recognises people who demonstrate critical customer-centric behaviours, • Develops and coaches their people to help them succeed, • Collaborates across boundaries and seeks to understand others to achieve collective goals, • Holds total accountability for their decisions and can defend their prioritiesExperience & Technical Requirements, • QFP, qualified franchise professional, • Proven experience in Legal and Contractual Law, • Extensive experience in franchising, • Experience in a regulated or financial services environment, • Working knowledge of audit, QA, or other compliance functions JBRP1_UKTJ

Title: Occupational Hygienist Description: The objective of this engagement is to ensure that occupational health, safety, ergonomics, and human factors principles are fully integrated into the design to eliminate or minimise health risks at source, with particular emphasis on the prevention of occupational disease and long-term health impacts. Key Responsibilities: The successful candidate shall provide occupational design services across all relevant project phases, including concept, preliminary, detailed design, and handover. Health-Focused Design Risk Identification Identify, assess, and mitigate health risks arising from design decisions, including but not limited to: • Noise exposure and control at source, • Vibration exposure (hand-arm and whole-body vibration), • Risks associated with carcinogens and cancer-causing agents, • Respiratory disorders, including exposure to dusts, fumes, vapours, and gases, • Skin reactions and dermatitis, including contact with hazardous substances, • Musculoskeletal disorders (MSDs) arising from poor ergonomics, manual handling, or repetitive tasks, • Exposure to hazardous substances, including COSHH-regulated substances, • Mental illness risks, including work-related stress, cognitive overload, isolation, and psychosocial hazards, • Review of potential exposure pathways for noise, vibration, hazardous substances, and airborne contaminants, • Assessment of engineering controls, substitution, enclosure, isolation, and ventilation, • Evaluation of design measures to eliminate or reduce reliance on administrative controls and PPE, • Assessment of design compliance with applicable occupational health and safety legislation, • Alignment with relevant regulations, codes of practice, and standards relating to:, • Occupational exposure limits, • COSHH / hazardous substances management, • Noise and vibration regulations, • Manual handling and ergonomics, • Health surveillance requirements, • Identification of gaps and non-compliances with recommended corrective actions Consultation and Integration • Liaison with the client, designers, engineers, and other stakeholders, • Participation in design risk workshops (e.g. HAZID, HAZOP, task-based risk assessments), • Attendance at design and coordination meetings as required. (Siemens to specify number), • Integration of occupational health considerations into safety-in-design processes Deliverables As a minimum, the Occupational Hygienist shall provide: • Occupational health design review reports at defined design stages, • Noise, vibration, and hazardous substance risk assessment inputs, • Ergonomic and human factors assessment reports, • Design risk register entries addressing occupational health hazards, • Written recommendations for risk elimination or reduction at design stage, • Contribution to safety-in-design and health-in-design documentation, • Final summary report demonstrating how client focus areas have been addressed, • Onsite assurance of OH hygiene provision - and clinical assessment, • Implement personal and onsite exposure monitoring regime and audit plan Qualifications/Experience: Essential • Appropriate qualifications in occupational health and safety, ergonomics, human factors, or related disciplines, • Proven experience addressing occupational health risks such as noise, Respiration, vibration, hazardous substances, MSDs, and mental health through design, • Knowledge of relevant occupational health legislation and best practice, • Experience working collaboratively within multi-disciplinary, • Experience in undertaking exposure monitoring and developing audit schedules and plans. Desirables • Experience within the construction and or rail industries - applying OH consultation., • Experience of providing written detailed OH reports., • Accredited by SEQOHS (Safe Effective Quality Occupational Health Service JBRP1_UKTJ

Content & Communications Manager (Partnership for Education) Salary: £35,200 - £45,700 per annum Location: Cambridge, UK with hybrid working Contract: Permanent Hours: Full time, 35 hours per week Do you have exceptional writing skills? Do you thrive when translating complex research, programmes and ideas into clear, engaging and accessible content to reach specific audiences? We are Cambridge University Press & Assessment, a world-leading academic publisher and assessment organisation and a proud part of the University of Cambridge. As part of our commitment to quality education for all, we have a dedicated team that works hand-in-hand with governments and organisations transforming education across whole regions and nations: Partnership for Education. As Content & Communications Manager for the Partnership for Education, you will be at the heart of shaping Cambridge's global voice on education reform. Drawing on policy and evidence, you'll create compelling thought leadership content and impact stories. You'll weave data and human stories into narratives that demonstrate how our work improves outcomes for teachers, learners and entire education systems. About the role Working alongside colleagues across the business, you'll: • Lead strategic storytelling and long‑form editorial content:, • Develop and deliver content marketing and thought‑leadership strategies aligned with our International Education priorities., • Research, plan, write and edit compelling case studies that blend data with human stories to bring our impact to life., • Produce authoritative content such as op‑eds, reports and speeches for senior leaders., • Create content across channels:, • Write and optimise website content, news stories, landing pages and copy that clearly articulate complex value propositions., • Translate long‑form content into multichannel assets for social, email and campaigns; ensure SEO/AEO best practice supports discoverability and engagement., • Turn complex insights into powerful narratives: Work closely with research, technical and delivery colleagues to distil research, monitoring and evaluation outputs into accessible and compelling content for governments and donor audiences. Additional responsibilities and accountabilities include: • Shaping visual storytelling:, • Briefing and collaborating with designers, photographers and videographers to deliver impactful visual assets, including infographics, photography and data‑led visuals., • Managing suppliers and upholding editorial excellence, • Commissioning and managing freelancers, ensuring outputs meet brand, accuracy, accessibility and narrative standards., • Championing our editorial style guide, tone of voice and quality standards across all content. This position has been classified as a hybrid role, requiring the selected candidate to typically spend 40-60% of their time collaborating and connecting face-to-face at their dedicated location. Aside from our hybrid principles, other flexible working requests will be considered from the first day of employment, including other work arrangements should you require adjustments due to a disability or long-term health condition. About You You'll be an experienced, proactive and audience focused storyteller who is confident working with complex subject matter. You'll bring: • Solid previous experience in content, communications or editorial roles, ideally within policy, education, international development or complex organisations., • Exceptional writing and editing skills across long‑form, product copy, digital content and short‑form channels and a passion for accuracy, Plain English, accessibility and brand guardianship., • Experience turning research and strategic insights into compelling, credible narratives., • Strong stakeholder engagement skills and confidence interviewing senior leaders and external partners., • Experience creating content in multiple languages for multiple audiences around the world., • An eye for effective design., • Strong organisational and time management skills and experience managing agencies, designers and freelancers., • Awareness of the education sector. If you meet the above minimum requirements, we encourage you to apply. Your application will be even stronger if you can also demonstrate the following desirable criteria: • Arabic language skills, • Knowledge of government stakeholders, • Awareness of AI copywriting developments and ethics, • Familiarity with SEO/AEO and content performance measurement and knowledge of data privacy and accessibility requirements. For a detailed job description, please refer to the link at the bottom of the advert on our careers site. We are a Disability Confident (DC) employer that is committed to equality and inclusion ensuring our recruitment process is accessible to all. The DC scheme's Offer of an Interview commitment applies to applicants who opt in, and disclose a disability or a long-term health condition, and best meet the minimum criteria for the role. In instances where interviewing all qualifying candidates is not practicable, we prioritise those who best meet the minimum criteria, as we would for applicants who do not have a disability or long-term health condition. Cambridge University Press & Assessment is an approved UK employer for the sponsorship of eligible roles and applicants under the Skilled Worker visa route. Please refer to the gov uk website for guidance to understand your own eligibility based on the role you are applying for. Rewards and benefits We will support you to be at your best in work and to live well outside of it. In addition to competitive salaries, we offer a world-class, flexible rewards package, featuring family-friendly and planet-friendly benefits including: • 28 days annual leave plus bank holidays, • Private medical and Permanent Health Insurance, • Discretionary annual bonus, • Group personal pension scheme, • Life assurance up to 4 x annual salary, • Green travel schemes Ready to pursue your potential? Apply now. We aim to support candidates by making our interview process clear and transparent. The closing date for all applications will be Friday 27 March. We will review applications on an ongoing basis, and shortlisted candidates can expect first interviews to take place on 7 and 8 April and final interviews on 14 April. If you are shortlisted and progressed through the stages, you can expect: • First stage virtual interview via MS Teams with the hiring manager and another colleague you'll be working closely with in the team., • Final stage interview: in-person at our offices in Cambridge with the hiring manager and the Director of Marketing & Communications, followed by informal coffee with several further members of the team. You will be provided with a brief to complete a role related task during the interview, there is no preparation required in advance. If you require any reasonable adjustments during the recruitment process due to a disability or a long-term health condition, there will be an opportunity for you to inform us via the online application form. We will do our best to accommodate your needs. Please note that successful applicants will be subject to satisfactory background checks including DBS due to working in a regulated industry. We are committed to an equitable recruitment process. As such, applications must be submitted via our official online application procedure. Please refrain from sending your CV directly to our recruiters. If you experience technical difficulties or require additional support with submitting your online application, contact the Recruiter. Why join us Joining us is your opportunity to pursue potential. You will belong to a collaborative team that is exploring new and better ways to serve students, teachers and researchers across the globe – for the benefit of individuals, society and the world. Sharing our mission will inspire your own growth, development and progress, in an environment which embraces difference, change and aspiration. Cambridge University Press & Assessment is committed to being a place where anyone can enjoy a successful career, where it is safe to speak up, and where we learn continuously to improve together. We welcome applications from all candidates, regardless of demographic characteristics (age, disability, educational attainment, ethnicity, gender, marital status, neurodiversity, religion, sex, gender identity and sexual identity), cultural, or social class/background. We believe better outcomes come through diversity of thought, background and approach. We welcome applications from people from all backgrounds and communities, actively seeking to employ people from a wide range of different communities. Content & Communications Manager - Apply now

Based in Cambridge, we are looking to recruit a Primary Teacher / Key Stage Lead for our excellent outstanding SEN school. Location : Cambridge Hours : Full time – term time only Salary : £35000 - £48000 per annum depending on experience Main Duties: * Be responsible for delivering a broad and balanced curriculum to a small class of pupils (no more than 10) * To take into consideration a range of curriculum approaches and specialist programmes so that the full needs of the learners are met. * To organise the classroom, its resources, pupil groupings and displays in order to provide a stimulating learning environment. * To share in the writing, evaluation and updating of pupil’s individual education plans and individual behaviour plans and contribute to termly and annual reports * Adhere to the school planning and record keeping systems and submit them for monitoring purposes on request. * To contribute to the recording of events and progress. * To manage and direct the support staff working within lessons. * Promote good communications with parents via home-school books, telephone calls and meetings. * To work effectively as a member of a multidisciplinary team, liaising with the Pastoral Manager, Key Stage Leads, School Leadership Team and Therapists as appropriate. * Keep up to date with developments in education, particularly related to ASC. * Adhere to all school policies and procedures and contribute to these in areas of responsibility. * Ensure regular completion and accuracy of * Incident Forms * Bullying Logs * Prejudice Logs * Be responsible for ensuring the completion, accuracy, quality and delivery of the end of term reports to parents, including up to date and accurate progress data * Check all Health and Safety Risk Assessments for Key Stage trips and outings for detail and accuracy * Establish regular Key Stage meetings to track and monitor: * Timetabling issues * Curriculum * Teaching and Learning matters * Staffing and Learner Matters * Organise Parents’ Evenings * Organise the Assembly rota, including external speakers and members of SLT, and disseminate any topics for delivery to relevant staff and learner groups * Organise any other meetings relevant to Key Stage for learners, parents and staff where deemed necessary * Provide regular staff supervision meetings for those you line manage, together with an annual appraisal * Participate in the school’s Lesson Observation Schedule, providing feedback to teachers on lessons delivered in the relevant Key Stage Person Spec * Qualified Teacher Status. * A good honours degree or equivalent * Experience of working with children and young people with a range of special educational needs The position is subject to an Enhanced DBS disclosure. As part of our commitment to safeguarding and promoting the welfare of the children and young people, the successful candidate is expected to undergo an enhanced DBS check. We are an equal opportunity employer and select staff on merit, irrespective of age, disability, gender reassignment, marriage & civil partnership, race, sex, sexual orientation, religion or belief. Refresh Recruitment Limited does not presently hold a Sponsorship License and while this status is reviewed regularly there is no present proposal to apply for such a License

The Head of Monitoring & Evaluation (M&E) will oversee AllChild’s programme monitoring processes, lead internal and external evaluation work and contribute to our evidence-led and impact-focused culture. We are seeking a collaborative project and people manager, with strong quantitative data manag

The postholder will help maintain high standards of experience for its beneficiaries and contribute to building a credible and transparent evidence base that strengthens the organisation’s long‑term sustainability and its influence on policy, research and knowledge sharing. Develop structured pr

The Equity Monitoring and Evaluation Manager drives delivery against Wellcome’s Equity Framework by designing, embedding and overseeing monitoring, evaluating and learning (MEL) approaches. Equity Monitoring and Evaluation Manager page is loaded## Equity Monitoring and Evaluation Managerlocations:

In collaboration with our Fellows and partners, we’re growing talent and developing skills for the future, driving innovation, and building global partnerships, and influencing policy and engaging the public. With a diverse workforce and an inclusive and supportive culture, we look to attract cand

Develop structured processes and timelines for sharing monitoring and evaluation findings with NSC team members to inform programme planning, recruitment and retention work. Clean and manage datasets - Working with the CRM Manager, develop dashboards for sharing live monitoring and evaluation data

The Head of Monitoring & Evaluation (M&E) will oversee AllChild's programme monitoring processes, lead internal and external evaluation work and contribute to our evidence-led and impact-focused culture. We are seeking a collaborative project and people manager, with strong quantitative data managem